Prashanthi D Vemuri, PhD

  • 10197 Citations
  • 53 Scopus h-Index
19992021
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Research Output 2004 2019

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Article
2013
48 Citations (Scopus)

Selective worsening of brain injury biomarker abnormalities in cognitively normal elderly persons with β-amyloidosis

Knopman, D. S., Jack, C. R. J., Wiste, H. J., Weigand, S. D., Vemuri, P. D., Lowe, V., Kantarci, K. M., Gunter, J. L., Senjem, M. L., Mielke, M. M., Roberts, R. O., Boeve, B. F. & Petersen, R. C., Aug 2013, In : JAMA Neurology. 70, 8, p. 1030-1038 9 p.

Research output: Contribution to journalArticle

Amyloidosis
Positron-Emission Tomography
Brain Injuries
Fluorodeoxyglucose F18
Biomarkers
41 Citations (Scopus)

Thrombogenic microvesicles and white matter hyperintensities in postmenopausal women

Raz, L., Jayachandran, M., Tosakulwong, N., Lesnick, T. G., Wille, S. M., Murphy, M., Senjem, M. L., Gunter, J. L., Vemuri, P. D., Jack, C. R. J., Miller, V. M. & Kantarci, K. M., Mar 5 2013, In : Neurology. 80, 10, p. 911-918 8 p.

Research output: Contribution to journalArticle

Platelet Activation
White Matter
Confidence Intervals
Activation
Random Allocation
1537 Citations (Scopus)

Tracking pathophysiological processes in Alzheimer's disease: An updated hypothetical model of dynamic biomarkers

Jack, C. R. J., Knopman, D. S., Jagust, W. J., Petersen, R. C., Weiner, M. W., Aisen, P. S., Shaw, L. M., Vemuri, P. D., Wiste, H. J., Weigand, S. D., Lesnick, T. G., Pankratz, V. S., Donohue, M. C. & Trojanowski, J. Q., Feb 2013, In : The Lancet Neurology. 12, 2, p. 207-216 10 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Biomarkers
Tauopathies
Amyloid
Brain Stem
2012
373 Citations (Scopus)

An operational approach to National Institute on Aging-Alzheimer's Association criteria for preclinical Alzheimer disease

Jack, C. R. J., Knopman, D. S., Weigand, S. D., Wiste, H. J., Vemuri, P. D., Lowe, V., Kantarci, K. M., Gunter, J. L., Senjem, M. L., Ivnik, R. J., Roberts, R. O., Rocca, W. A., Boeve, B. F. & Petersen, R. C., Jun 2012, In : Annals of Neurology. 71, 6, p. 765-775 11 p.

Research output: Contribution to journalArticle

National Institute on Aging (U.S.)
Alzheimer Disease
Biomarkers
Positron-Emission Tomography
Population
41 Citations (Scopus)
Myelin Basic Protein
Oligodendroglia
Pathology
Extracellular Fluid
Brain
17 Citations (Scopus)
Chromosomes, Human, Pair 9
Amyotrophic Lateral Sclerosis
Open Reading Frames
Neuroimaging
Parkinsonian Disorders
226 Citations (Scopus)
Parkinsonian Disorders
Age of Onset
Frontotemporal Dementia
Chromosomes, Human, Pair 9
Neuroimaging
165 Citations (Scopus)

Diagnostic neuroimaging across diseases

Klöppel, S., Abdulkadir, A., Jack, C. R. J., Koutsouleris, N., Mourão-Miranda, J. & Vemuri, P. D., Jun 2012, In : NeuroImage. 61, 2, p. 457-463 7 p.

Research output: Contribution to journalArticle

Neuroimaging
Uncertainty
Psychiatry
Disease Progression
Schizophrenia
89 Citations (Scopus)

Effect of lifestyle activities on alzheimer disease biomarkers and cognition

Vemuri, P. D., Lesnick, T. G., Przybelski, S. A., Knopman, D. S., Roberts, R. O., Lowe, V., Kantarci, K. M., Senjem, M. L., Gunter, J. L., Boeve, B. F., Petersen, R. C. & Jack, C. R. J., Nov 2012, In : Annals of Neurology. 72, 5, p. 730-738 9 p.

Research output: Contribution to journalArticle

Cognition
Life Style
Alzheimer Disease
Biomarkers
Positron-Emission Tomography
53 Citations (Scopus)

Focal atrophy on MRI and neuropathologic classification of dementia with Lewy bodies

Kantarci, K. M., Ferman, T. J., Boeve, B. F., Weigand, S. D., Przybelski, S., Vemuri, P. D., Murray, M. E., Senjem, M. L., Smith, G. E., Knopman, D. S., Petersen, R. C., Jack, C. R. J., Parisi, J. E. & Dickson, D. W., Aug 7 2012, In : Neurology. 79, 6, p. 553-560 8 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Atrophy
Alzheimer Disease
Dementia
Lewy Bodies
37 Citations (Scopus)

Imaging and acetylcholinesterase inhibitor response in dementia with Lewy bodies

Graff-Radford, J., Boeve, B. F., Pedraza, O. D., Ferman, T. J., Przybelski, S., Lesnick, T. G., Vemuri, P. D., Senjem, M. L., Smith, G. E., Knopman, D. S., Lowe, V., Jack, C. R. J., Petersen, R. C. & Kantarci, K. M., Aug 2012, In : Brain. 135, 8, p. 2470-2477 8 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Cholinesterase Inhibitors
Positron-Emission Tomography
Dementia
Alzheimer Disease
91 Citations (Scopus)

Indicators of amyloid burden in a population-based study of cognitively normal elderly

Mielke, M. M., Wiste, H. J., Weigand, S. D., Knopman, D. S., Lowe, V., Roberts, R. O., Geda, Y. E., Swenson-Dravis, D. M., Boeve, B. F., Senjem, M. L., Vemuri, P. D., Petersen, R. C. & Jack, C. R. J., Oct 9 2012, In : Neurology. 79, 15, p. 1570-1577 8 p.

Research output: Contribution to journalArticle

Amyloid
Population
ROC Curve
Genotype
Amyloidosis
201 Citations (Scopus)

Non-stationarity in the "resting brain's" modular architecture

Jones, D. T., Vemuri, P. D., Murphy, M., Gunter, J. L., Senjem, M. L., Machulda, M. M., Przybelski, S. A., Gregg, B. E., Kantarci, K. M., Knopman, D. S., Boeve, B. F., Petersen, R. C. & Jack, C. R. J., Jun 28 2012, In : PLoS One. 7, 6, e39731.

Research output: Contribution to journalArticle

magnetic resonance imaging
Brain
dementia
brain
nervous system
54 Citations (Scopus)
Alzheimer Disease
Magnetic Resonance Imaging
Biomarkers
Brain
83 Citations (Scopus)

Shapes of the trajectories of 5 major biomarkers of Alzheimer disease

Jack, C. R. J., Vemuri, P. D., Wiste, H. J., Weigand, S. D., Lesnick, T. G., Lowe, V., Kantarci, K. M., Bernstein, M. A., Senjem, M. L., Gunter, J. L., Boeve, B. F., Trojanowski, J. Q., Shaw, L. M., Aisen, P. S., Weiner, M. W., Petersen, R. C. & Knopman, D. S., Jul 2012, In : Archives of Neurology. 69, 7, p. 856-867 12 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Biomarkers
Amyloid
Positron-Emission Tomography
Alzheimer's Disease
182 Citations (Scopus)

Short-term clinical outcomes for stages of NIA-AA preclinical Alzheimer disease

Knopman, D. S., Jack, C. R. J., Wiste, H. J., Weigand, S. D., Vemuri, P. D., Lowe, V., Kantarci, K. M., Gunter, J. L., Senjem, M. L., Ivnik, R. J., Roberts, R. O., Boeve, B. F. & Petersen, R. C., May 15 2012, In : Neurology. 78, 20, p. 1576-1582 7 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Dementia
Amyloid
National Institute on Aging (U.S.)
Aptitude
2011
181 Citations (Scopus)

Age-related changes in the default mode network are more advanced in Alzheimer disease

Jones, D. T., Machulda, M. M., Vemuri, P. D., McDade, E. M., Zeng, G., Senjem, M. L., Gunter, J. L., Przybelski, S. A., Avula, R. T., Knopman, D. S., Boeve, B. F., Petersen, R. C. & Jack, C. R. J., Oct 18 2011, In : Neurology. 77, 16, p. 1524-1531 8 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Education
Frontal Lobe
Atrophy
Alleles
82 Citations (Scopus)

Altered functional connectivity in asymptomatic MAPT subjects A comparison to bvFTD

Whitwell, J. L., Josephs, K. A., Avula, R., Tosakulwong, N., Weigand, S. D., Senjem, M. L., Vemuri, P. D., Jones, D. T., Gunter, J. L., Baker, M., Wszolek, Z. K., Knopman, D. S., Rademakers, R. V., Petersen, R. C., Boeve, B. F. & Jack, C. R. J., Aug 30 2011, In : Neurology. 77, 9, p. 866-874 9 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Microtubule-Associated Proteins
Parietal Lobe
Temporal Lobe
Cerebral Cortex
61 Citations (Scopus)

Antemortem differential diagnosis of dementia pathology using structural MRI: Differential-STAND

Vemuri, P. D., Simon, G., Kantarci, K. M., Whitwell, J. L., Senjem, M. L., Przybelski, S. A., Gunter, J. L., Josephs, K. A., Knopman, D. S., Boeve, B. F., Ferman, T. J., Dickson, D. W., Parisi, J. E., Petersen, R. C. & Jack, C. R. J., Mar 15 2011, In : NeuroImage. 55, 2, p. 522-531 10 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Lewy Body Disease
Dementia
Differential Diagnosis
Pathology
81 Citations (Scopus)

Cognitive reserve and Alzheimer's disease biomarkers are independent determinants of cognition

Vemuri, P. D., Weigand, S. D., Przybelski, S. A., Knopman, D. S., Smith, G. E., Trojanowski, J. Q., Shaw, L. M., Decarli, C. S., Carmichael, O., Bernstein, M. A., Aisen, P. S., Weiner, M., Petersen, R. C. & Jack, C. R. J., May 2011, In : Brain. 134, 5, p. 1479-1492 14 p.

Research output: Contribution to journalArticle

Cognitive Reserve
Cognition
Alzheimer Disease
Biomarkers
Reading
86 Citations (Scopus)

Diffusion tensor imaging and cognitive function in older adults with no dementia

Kantarci, K. M., Senjem, M. L., Avula, R., Zhang, B., Samikoglu, A. R., Weigand, S. D., Przybelski, S. A., Edmonson, H. A., Vemuri, P. D., Knopman, D. S., Boeve, B. F., Ivnik, R. J., Smith, G. E., Petersen, R. C. & Jack, C. R. J., Jul 5 2011, In : Neurology. 77, 1, p. 26-34 9 p.

Research output: Contribution to journalArticle

Diffusion Tensor Imaging
Anisotropy
Cognition
Dementia
Executive Function
94 Citations (Scopus)

Disrupted thalamocortical connectivity in PSP: A resting-state fMRI, DTI, and VBM study

Whitwell, J. L., Avula, R., Master, A., Vemuri, P. D., Senjem, M. L., Jones, D. T., Jack, C. R. J. & Josephs, K. A., Sep 2011, In : Parkinsonism and Related Disorders. 17, 8, p. 599-605 7 p.

Research output: Contribution to journalArticle

Progressive Supranuclear Palsy
Motor Cortex
Magnetic Resonance Imaging
Thalamus
Basal Ganglia
141 Citations (Scopus)

Effect of APOE ε4 status on intrinsic network connectivity in cognitively normal elderly subjects

Machulda, M. M., Jones, D. T., Vemuri, P. D., McDade, E., Avula, R., Przybelski, S., Boeve, B. F., Knopman, D. S., Petersen, R. C. & Jack, C. R. J., Sep 2011, In : Archives of Neurology. 68, 9, p. 1131-1136 6 p.

Research output: Contribution to journalArticle

Gyrus Cinguli
Sex Education
Temporal Lobe
Seeds
Parietal Lobe
51 Citations (Scopus)

Effects of hardware heterogeneity on the performance of SVM Alzheimer's disease classifier

Abdulkadir, A., Mortamet, B., Vemuri, P. D., Jack, C. R. J., Krueger, G. & Klöppel, S., Oct 1 2011, In : NeuroImage. 58, 3, p. 785-792 8 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Magnetic Resonance Imaging
Neuroimaging
Sample Size
Meta-Analysis
158 Citations (Scopus)

Evidence for ordering of Alzheimer disease biomarkers

Jack, C. R. J., Vemuri, P. D., Wiste, H. J., Weigand, S. D., Aisen, P. S., Trojanowski, J. Q., Shaw, L. M., Bernstein, M. A., Petersen, R. C., Weiner, M. W. & Knopman, D. S., Dec 2011, In : Archives of Neurology. 68, 12, p. 1526-1535 10 p.

Research output: Contribution to journalArticle

Cerebrospinal Fluid
Alzheimer Disease
Biomarkers
Alzheimer's Disease
Mild Cognitive Impairment
17 Citations (Scopus)
Atrophy
Alzheimer Disease
Cognitive Dysfunction
Sex Education
Temporal Lobe
74 Citations (Scopus)

Transforming cerebrospinal fluid Aβ42 measures into calculated Pittsburgh compound B units of brain Aβ amyloid

Weigand, S. D., Vemuri, P. D., Wiste, H. J., Senjem, M. L., Pankratz, V. S., Aisen, P. S., Weiner, M. W., Petersen, R. C., Shaw, L. M., Trojanowski, J. Q., Knopman, D. S. & Jack, C. R. J., Mar 2011, In : Alzheimer's and Dementia. 7, 2, p. 133-141 9 p.

Research output: Contribution to journalArticle

Amyloid
Positron-Emission Tomography
Cerebrospinal Fluid
Alzheimer Disease
Neuroimaging
2010
324 Citations (Scopus)

Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer's disease

Jack, C. R. J., Wiste, H. J., Vemuri, P. D., Weigand, S. D., Senjem, M. L., Zeng, G., Bernstein, M. A., Gunter, J. L., Pankratz, V. S., Aisen, P. S., Weiner, M. W., Petersen, R. C., Shaw, L. M., Trojanowski, J. Q. & Knopman, D. S., Nov 2010, In : Brain. 133, 11, p. 3336-3348 13 p.

Research output: Contribution to journalArticle

Amyloid
Atrophy
Alzheimer Disease
Magnetic Resonance Imaging
Brain
122 Citations (Scopus)

Dementia with Lewy bodies and Alzheimer disease: Neurodegenerative patterns characterized by DTI

Kantarci, K. M., Avula, R., Senjem, M. L., Samikoglu, A. R., Zhang, B., Weigand, S. D., Przybelski, S. A., Edmonson, H. A., Vemuri, P. D., Knopman, D. S., Ferman, T. J., Boeve, B. F., Petersen, R. C. & Jack, C. R. J., Jun 1 2010, In : Neurology. 74, 22, p. 1814-1821 8 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Diffusion Magnetic Resonance Imaging
Dementia
Alzheimer Disease
Amygdala
116 Citations (Scopus)

Effect of apolipoprotein E on biomarkers of amyloid load and neuronal pathology in Alzheimer disease

Vemuri, P. D., Wiste, H. J., Weigand, S. D., Knopman, D. S., Shaw, L. M., Trojanowski, J. Q., Aisen, P. S., Weiner, M., Petersen, R. C. & Jack, C. R. J., Mar 2010, In : Annals of Neurology. 67, 3, p. 308-316 9 p.

Research output: Contribution to journalArticle

Apolipoproteins E
Amyloid
Cerebrospinal Fluid
Alzheimer Disease
Biomarkers
152 Citations (Scopus)

Gray and white matter water diffusion in the syndromic variants of frontotemporal dementia

Whitwell, J. L., Avula, R., Senjem, M. L., Kantarci, K. M., Weigand, S. D., Samikoglu, A., Edmonson, H. A., Vemuri, P. D., Knopman, D. S., Boeve, B. F., Petersen, R. C., Josephs, K. A. & Jack, C. R. J., Apr 2010, In : Neurology. 74, 16, p. 1279-1287 9 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Primary Progressive Nonfluent Aphasia
Water
Diffusion Tensor Imaging
Frontal Lobe
48 Citations (Scopus)

Role of structural MRI in Alzheimer's disease

Vemuri, P. D. & Jack, C. R. J., 2010, In : Alzheimer's Research and Therapy. 2, 4, 23.

Research output: Contribution to journalArticle

Alzheimer Disease
Magnetic Resonance Imaging
Biomarkers
Atrophy
Pathology
108 Citations (Scopus)

Serial MRI and CSF biomarkers in normal aging, MCI, and AD

Vemuri, P. D., Wiste, H. J., Weigand, S. D., Knopman, D. S., Trojanowski, J. Q., Shaw, L. M., Bernstein, M. A., Aisen, P. S., Weiner, M., Petersen, R. C. & Jack, C. R. J., Jul 13 2010, In : Neurology. 75, 2, p. 143-151 9 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Biomarkers
Sample Size
Genotype
Clinical Trials
2009
166 Citations (Scopus)

Distinct anatomical subtypes of the behavioural variant of frontotemporal dementia: A cluster analysis study

Whitwell, J. L., Przybelski, S. A., Weigand, S. D., Ivnik, R. J., Vemuri, P. D., Gunter, J. L., Senjem, M. L., Shiung, M. M., Boeve, B. F., Knopman, D. S., Parisi, J. E., Dickson, D. W., Petersen, R. C., Jack, C. R. J. & Josephs, K. A., Nov 2009, In : Brain. 132, 11, p. 2932-2946 15 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Cluster Analysis
Frontal Lobe
Temporal Lobe
Atrophy
260 Citations (Scopus)

MRI and CSF biomarkers in normal, MCI, and AD subjects: Predicting future clinical change

Vemuri, P. D., Wiste, H. J., Weigand, S. D., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W., Knopman, D. S., Petersen, R. C. & Jack, C. R. J., Jul 2009, In : Neurology. 73, 4, p. 294-301 8 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Biomarkers
Aptitude
Proportional Hazards Models
Neuroimaging
187 Citations (Scopus)

MRI and CSF biomarkers in normal, MCI, and AD subjects: Diagnostic discrimination and cognitive correlations

Vemuri, P. D., Wiste, H. J., Weigand, S. D., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W., Knopman, D. S., Petersen, R. C. & Jack, C. R. J., Jul 2009, In : Neurology. 73, 4, p. 287-293 7 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Biomarkers
Information Storage and Retrieval
Neuroimaging
Cognition
77 Citations (Scopus)

Two distinct subtypes of right temporal variant frontotemporal dementia

Josephs, K. A., Whitwell, J. L., Knopman, D. S., Boeve, B. F., Vemuri, P. D., Senjem, M. L., Parisi, J. E., Ivnik, R. J., Dickson, D. W., Petersen, R. C. & Jack, C. R. J., Nov 2009, In : Neurology. 73, 18, p. 1443-1450 8 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Pathology
Prosopagnosia
tau Proteins
Behavioral Symptoms
2008
300 Citations (Scopus)

Alzheimer's disease diagnosis in individual subjects using structural MR images: Validation studies

Vemuri, P. D., Gunter, J. L., Senjem, M. L., Whitwell, J. L., Kantarci, K. M., Knopman, D. S., Boeve, B. F., Petersen, R. C. & Jack, C. R. J., Feb 1 2008, In : NeuroImage. 39, 3, p. 1186-1197 12 p.

Research output: Contribution to journalArticle

Validation Studies
Alzheimer Disease
Libraries
Demography
Apolipoproteins E
112 Citations (Scopus)
Neurofibrillary Tangles
Magnetic Resonance Imaging
Alzheimer Disease
Atrophy
Pathology
219 Citations (Scopus)

MRI correlates of neurofibrillary tangle pathology at autopsy: A voxel-based morphometry study

Whitwell, J. L., Josephs, K. A., Murray, M. E., Kantarci, K. M., Przybelski, S. A., Weigand, S. D., Vemuri, P. D., Senjem, M. L., Parisi, J. E., Knopman, D. S., Boeve, B. F., Petersen, R. C., Dickson, D. W. & Jack, C. R. J., Sep 2 2008, In : Neurology. 71, 10, p. 743-749 7 p.

Research output: Contribution to journalArticle

Neurofibrillary Tangles
Autopsy
Pathology
Atrophy
Alzheimer Disease
63 Citations (Scopus)

The anatomic correlate of prosopagnosia in semantic dementia

Josephs, K. A., Whitwell, J. L., Vemuri, P. D., Senjem, M. L., Boeve, B. F., Knopman, D. S., Smith, G. E., Ivnik, R. J., Petersen, R. C. & Jack, C. R. J., Nov 11 2008, In : Neurology. 71, 20, p. 1628-1633 6 p.

Research output: Contribution to journalArticle

Prosopagnosia
Frontotemporal Dementia
Temporal Lobe
Amygdala
Atrophy
2005
13 Citations (Scopus)

Automatic detection of three-dimensional vascular tree centerlines and bifurcations in high-resolution magnetic resonance angiography

Zhang, L., Chapman, B. E., Parker, D. L., Roberts, J. A., Guo, J., Vemuri, P. D., Moon, S. M. & Noo, F., Oct 2005, In : Investigative Radiology. 40, 10, p. 661-671 11 p.

Research output: Contribution to journalArticle

Magnetic Resonance Angiography
Blood Vessels
Costs and Cost Analysis
Skeleton
29 Citations (Scopus)
Signal-To-Noise Ratio
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
2004
2 Citations (Scopus)

Statistics-based approach for aneurysm volume measurements

Vemuri, P. D., Kholmovski, E. G., Goodrich, K. C., Zhang, L., Tsuruda, J. S. & Parker, D. L., Aug 2004, In : Journal of Magnetic Resonance Imaging. 20, 2, p. 340-346 7 p.

Research output: Contribution to journalArticle

Aneurysm
Intracranial Aneurysm
Datasets