Petras P Dzeja, PhD

  • 6246 Citations
  • 40 Scopus h-Index
1980 …2019

Research output per year

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Research Output

Article

<sup>18</sup>O-assisted <sup>31</sup>P NMR and mass spectrometry for phosphometabolomic fingerprinting and metabolic monitoring

Nemutlu, E., Zhang, S., Terzic, A. & Dzeja, P. P., 2015, In : Issues in Toxicology. 2015-January, 21, p. 255-286 32 p.

Research output: Contribution to journalArticle

1 Scopus citations

18O-assisted dynamic metabolomics for individualized diagnostics and treatment of human diseases

Nemutlu, E., Zhang, S., Juranic, N. O., Terzic, A., Macura, S. I. & Dzeja, P. P., 2012, In : Croatian Medical Journal. 53, 6, p. 529-534 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

31P NMR correlation maps of 18O/16O chemical shift isotopic effects for phosphometabolite labeling studies

Juranić, N., Nemutlu, E., Zhang, S., Dzeja, P. P., Terzic, A. & Macura, S. I., Jul 2011, In : Journal of Biomolecular NMR. 50, 3, p. 237-245 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity

Kazak, L., Rahbani, J. F., Samborska, B., Lu, G. Z., Jedrychowski, M. P., Lajoie, M., Zhang, S., Ramsay, L. A., Dou, F. Y., Tenen, D., Chouchani, E. T., Dzeja, P., Watson, I. R., Tsai, L., Rosen, E. D. & Spiegelman, B. M., Mar 1 2019, In : Nature Metabolism. 1, 3, p. 360-370 11 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Adenylate kinase: Kinetic behavior in intact cells indicates it is integral to multiple cellular processes

Dzeja, P. P., Zeleznikar, R. J. & Goldberg, N. D., 1998, In : Molecular and Cellular Biochemistry. 184, 1-2, p. 169-182 14 p.

Research output: Contribution to journalArticle

119 Scopus citations

Adenylate kinase 1 deficiency induces molecular and structural adaptations to support muscle energy metabolism

Janssen, E., De Groof, A., Wijers, M., Fransen, J., Dzeja, P. P., Terzic, A. & Wieringa, B., Apr 11 2003, In : Journal of Biological Chemistry. 278, 15, p. 12937-12945 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

Adenylate kinase 1 gene deletion disrupts muscle energetic economy despite metabolic rearrangement

Janssen, E., Dzeja, P. P., Oerlemans, F., Simonetti, A. W., Heerschap, A., De Haan, A., Rush, P. S., Terjung, R. R., Wieringa, B. & Terzic, A., Dec 1 2000, In : EMBO Journal. 19, 23, p. 6371-6381 11 p.

Research output: Contribution to journalArticle

111 Scopus citations

Adenylate kinase AK1 knockout heart: Energetics and functional performance under ischemia-reperfusion

Pucar, D., Bast, P., Gumina, R. J., Lim, L., Drahl, C., Juranic, N., Macura, S. I., Janssen, E., Wieringa, B., Terzic, A. & Dzeja, P. P., 2002, In : American Journal of Physiology - Heart and Circulatory Physiology. 283, 2 52-2

Research output: Contribution to journalArticle

48 Scopus citations
211 Scopus citations

Adenylate kinase-catalyzed phosphoryl transfer couples ATP utilization with its generation by glycolysis in intact muscle

Zeleznikar, R. J., Dzeja, P. P. & Goldberg, N. D., 1995, In : Journal of Biological Chemistry. 270, 13, p. 7311-7319 9 p.

Research output: Contribution to journalArticle

102 Scopus citations

Adenylate kinase-catalyzed phosphotransfer in the myocardium: Increased contribution in heart failure

Dzeja, P. P., Vitkevicius, K. T., Redfield, M. M., Burnett, J. C. J. & Terzic, A., May 28 1999, In : Circulation Research. 84, 10, p. 1137-1143 7 p.

Research output: Contribution to journalArticle

159 Scopus citations

Adenylate kinase phosphotransfer communicates cellular energetic signals to ATP-sensitive potassium channels

Carrasco, A. J., Dzeja, P. P., Alekseev, A. E., Pucar, D., Zingman, L. V., Abraham, M. R., Hodgson, D., Bienengraeber, M., Puceat, M., Janssen, E., Wieringa, B. & Terzic, A., Jun 19 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 13, p. 7623-7628 6 p.

Research output: Contribution to journalArticle

201 Scopus citations

A pharmaco-metabonomic study on chronic kidney disease and therapeutic effect of Ergone by UPLC-QTOF/HDMS

Zhao, Y. Y., Chen, H., Tian, T., Chen, D. Q., Bai, X., Wei, F. & Dzeja, P. P., Dec 23 2014, In : PLoS One. 9, 12, e115467.

Research output: Contribution to journalArticle

49 Scopus citations

ATPase activity of the sulfonylurea receptor: A catalytic function for the K(ATP) channel complex

Bienengraeber, M., Alekseev, A. E., Abraham, M. R., Carrasco, A. J., Moreau, C., Vivaudou, M., Dzeja, P. P. & Terzic, A., 2000, In : FASEB Journal. 14, 13, p. 1943-1952 10 p.

Research output: Contribution to journalArticle

124 Scopus citations

ATPase of the sulfonylurea receptor and KATP channel gating

Zingman, L. V., Alekseev, A. E., Bienengraeber, M., Dzeja, P. P. & Terzic, A., 2001, In : Clinical Pharmacology and Therapeutics. 69, 2

Research output: Contribution to journalArticle

ATP-sensitive K+ channel knockout compromises the metabolic benefit of exercise training, resulting in cardiac deficits

Kane, G. M., Behfar, A., Yamada, S., Terzic, C. M., O'Cochlain, F., Reyes, S., Dzeja, P. P., Miki, T., Seino, S. & Terzic, A., Dec 2004, In : Diabetes. 53, SUPPL. 3

Research output: Contribution to journalArticle

88 Scopus citations
16 Scopus citations
12 Scopus citations

Cardiac resynchronization therapy induces adaptive metabolic transitions in the metabolomic profile of heart failure

Nemutlu, E., Zhang, S., Xu, Y. Z., Terzic, A., Zhong, L., Dzeja, P. P. & Cha, Y-M., Jun 1 2015, In : Journal of Cardiac Failure. 21, 6, p. 460-469 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Cardiac system bioenergetics: Metabolic basis of the frank-starling law

Saks, V., Dzeja, P. P., Schlattner, U., Vendelin, M., Terzic, A. & Wallimann, T., Mar 2006, In : Journal of Physiology. 571, 2, p. 253-273 21 p.

Research output: Contribution to journalArticle

180 Scopus citations

Cellular energetics in the preconditioned state: Protective role for phosphotransfer reactions captured by 18O-assisted 31P NMR

Pucar, D., Dzeja, P. P., Bast, P., Juranic, N., Macura, S. I. & Terzic, A., Nov 30 2001, In : Journal of Biological Chemistry. 276, 48, p. 44812-44819 8 p.

Research output: Contribution to journalArticle

76 Scopus citations

Changes in adenylate kinase isozyme activity in the ischemic rabbit heart

Vitkevicius, K. T. & Dzeja, P. P., Aug 1990, In : Bulletin of Experimental Biology and Medicine. 110, 2, p. 1039-1040 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Changes in energy transduction efficiency in mitochondria isolated from ischemic myocardium.

Toleikis, A., Dzeja, P. P. & Praskevicius, A., 1980, In : Advances in myocardiology. 2, p. 327-337 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Compartmentation of membrane processes and nucleotide dynamics in diffusion-restricted cardiac cell microenvironment

Alekseev, A. E., Reyes, S., Selivanov, V. A., Dzeja, P. P. & Terzic, A., Feb 2012, In : Journal of Molecular and Cellular Cardiology. 52, 2, p. 401-409 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Compromised energetics in the adenylate kinase AK1 gene knockout heart under metabolic stress

Pucar, D., Janssen, E., Dzeja, P. P., Juranic, N., Macura, S. I., Wieringa, B. & Terzic, A., Dec 29 2000, In : Journal of Biological Chemistry. 275, 52, p. 41424-41429 6 p.

Research output: Contribution to journalArticle

68 Scopus citations

Coupling of cell energetics with membrane metabolic sensing: Integrative signaling through creatine kinase phosphotransfer disrupted by M-CK gene knock-out

Roselle Abraham, M., Selivanov, V. A., Hodgson, D. M., Pucar, D., Zingman, L. V., Wieringa, B., Dzeja, P. P., Alekseev, A. E. & Terzic, A., Jul 5 2002, In : Journal of Biological Chemistry. 277, 27, p. 24427-24434 8 p.

Research output: Contribution to journalArticle

126 Scopus citations

Decline of phosphotransfer and substrate supply metabolic circuits hinders ATP cycling in aging myocardium

Nemutlu, E., Gupta, A., Zhang, S., Viqar, M., Holmuhamedov, E., Terzic, A., Jahangir, A. & Dzeja, P. P., Sep 17 2015, In : PLoS One. 10, 9, e0136556.

Research output: Contribution to journalArticle

5 Scopus citations

Defective metabolic signaling in adenylate kinase AK1 gene knock-out hearts compromises post-ischemic coronary reflow

Dzeja, P. P., Bast, P., Pucar, D., Wieringa, B. & Terzic, A., Oct 26 2007, In : Journal of Biological Chemistry. 282, 43, p. 31366-31372 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial alzheimer's disease

Trushina, E. D., Nemutlu, E., Zhang, S., Christensen, T., Camp, J., Mesa, J., Siddiqui, A., Tamura, Y., Sesaki, H., Wengenack, T. M., Dzeja, P. P. & Poduslo, J. F., Feb 29 2012, In : PLoS One. 7, 2, e32737.

Research output: Contribution to journalArticle

149 Scopus citations

Developmental enhancement of adenylate kinase-AMPK metabolic signaling axis supports stem cell cardiac differentiation

Dzeja, P. P., Chung, S., Faustino, R. S., Behfar, A. & Terzic, A., 2011, In : PLoS One. 6, 4, e19300.

Research output: Contribution to journalArticle

36 Scopus citations

Directed Inhibition of Nuclear Import in Cellular Hypertrophy

Terzic, C. M., Gacy, A. M., Bortolon, R., Dzeja, P. P., Puceat, M., Jaconi, M., Prendergast, F. G. & Terzic, A., Jun 8 2001, In : Journal of Biological Chemistry. 276, 23, p. 20566-20571 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Doppler Strain Imaging Closely Reflects Myocardial Energetic Status in Acute Progressive Ischemia and Indicates Energetic Recovery After Reperfusion

Korinek, J., Sengupta, P. P., Wang, J., Romero-Corral, A., Boukatina, A. E., Vitek, J., Krishnamoorthy, V. K., Cha, S. S., Dzeja, P. P., Terzic, A., Khandheria, B. K. & Belohlavek, M., Aug 2008, In : Journal of the American Society of Echocardiography. 21, 8, p. 961-968 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Dynamic phosphometabolomic profiling of human tissues and transgenic models by 18O-assisted 31P NMR and mass spectrometry

Nemutlu, E., Zhang, S., Gupta, A., Juranic, N. O., Macura, S. I., Terzic, A., Jahangir, A. & Dzeja, P. P., Apr 1 2012, In : Physiological Genomics. 44, 7, p. 386-402 17 p.

Research output: Contribution to journalArticle

15 Scopus citations

Effect of elemental sulphur on the activity of adenylate kinase and performance of isolated rabbit heart

Dagys, A. I., Vitkevicius, K. T., Balciunas, G. A., Gendviliene, V. I., Dzeja, P. P. & Toleikis, A. I., 1990, In : Byulleten Eksperimentalnoi Biologii i Meditsiny. 108, 10, p. 377-379 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Effect of elementary sulfur on adenylate kinase activity and working of the isolated rabbit heart

Dagys, A. I., Vitkevičius, K. T., Balčiunas, G. A., Gendviliene, V. I., Dzeja, P. P. & Toleikis, A. I., Oct 1990, In : Bulletin of Experimental Biology and Medicine. 110, 4, p. 1355-1357 3 p.

Research output: Contribution to journalArticle

Electron spray ionization mass spectrometry and 2D 31P NMR for monitoring 18O/16O isotope exchange and turnover rates of metabolic oligophosphates

Nemutlu, E., Juranic, N., Zhang, S., Ward, L. E., Dutta, T., Nair, K. S., Terzic, A., Macura, S. I. & Dzeja, P. P., May 2012, In : Analytical and Bioanalytical Chemistry. 403, 3, p. 697-706 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Energetic communication between mitochondria and nucleus directed by catalyzed phosphotransfer

Dzeja, P. P., Bortolon, R., Terzic, C. M., Holmuhamedov, E. L. & Terzic, A., Jul 23 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 15, p. 10156-10161 6 p.

Research output: Contribution to journalArticle

117 Scopus citations

Energy metabolism plasticity enables stemness programs

Folmes, C., Nelson, T. J., Dzeja, P. P. & Terzic, A., Apr 2012, In : Annals of the New York Academy of Sciences. 1254, 1, p. 82-89 8 p.

Research output: Contribution to journalArticle

63 Scopus citations
82 Scopus citations

Failing energetics in failing hearts

Dzeja, P. P., Redfield, M. M., Burnett, J. C. J. & Terzic, A., 2000, In : Current Cardiology Reports. 2, 3, p. 212-217 6 p.

Research output: Contribution to journalArticle

86 Scopus citations

First and second trimester urinary metabolic profiles and fetal growth restriction: An exploratory nested case-control study within the infant development and environment study

Luthra, G., Vuckovic, I., Bangdiwala, A., Gray, H., Redmon, J. B., Barrett, E. S., Sathyanarayana, S., Nguyen, R. H. N., Swan, S. H., Zhang, S., Dzeja, P. P., Macura, S. I. & Nair, K. S., Feb 8 2018, In : BMC Pregnancy and Childbirth. 18, 1, 48.

Research output: Contribution to journalArticle

3 Scopus citations

Functional alterations in the mitochondrial site of adenylate kinase and creatine kinase energy transport systems induced by myocardial ischemia and adriblastin

Toleikis, A. J., Kalvenas, A. A., Dzeja, P. P., Praskevicius, A. K. & Jasaitis, A. A., 1988, In : Biokhimiya. 53, 4

Research output: Contribution to journalArticle

9 Scopus citations

Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity

Kazak, L., Chouchani, E. T., Lu, G. Z., Jedrychowski, M. P., Bare, C. J., Mina, A. I., Kumari, M., Zhang, S., Vuckovic, I., Laznik-Bogoslavski, D., Dzeja, P. P., Banks, A. S., Rosen, E. D. & Spiegelman, B. M., 2017, (Accepted/In press) In : Cell Metabolism.

Research output: Contribution to journalArticle

52 Scopus citations

Glycolytic network restructuring integral to the energetics of embryonic stem cell cardiac differentiation

Chung, S., Arrell, D. K., Faustino, R. S., Terzic, A. & Dzeja, P. P., Apr 2010, In : Journal of Molecular and Cellular Cardiology. 48, 4, p. 725-734 10 p.

Research output: Contribution to journalArticle

91 Scopus citations

Glycolytic Stimulation Is Not a Requirement for M2 Macrophage Differentiation

Wang, F., Zhang, S., Vuckovic, I., Jeon, R., Lerman, A., Folmes, C., Dzeja, P. P. & Herrmann, J., Sep 4 2018, In : Cell Metabolism. 28, 3, p. 463-475.e4

Research output: Contribution to journalArticle

29 Scopus citations

Guided stem cell cardiopoiesis: Discovery and translation

Behfar, A., Faustino, R. S., Arrell, D. K., Dzeja, P. P., Terzic, C. M. & Terzic, A., Oct 2008, In : Journal of Molecular and Cellular Cardiology. 45, 4, p. 523-529 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

Impaired intracellular energetic communication in muscles from creatine kinase and adenylate kinase (M-CK/AK1) double knock-out mice

Janssen, E., Terzic, A., Wieringa, B. & Dzeja, P. P., Aug 15 2003, In : Journal of Biological Chemistry. 278, 33, p. 30441-30449 9 p.

Research output: Contribution to journalArticle

51 Scopus citations

Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages to Sustain Cell Viability and Pro-Inflammatory Activity

Wang, F., Zhang, S., Jeon, R., Vuckovic, I., Jiang, X., Lerman, A., Folmes, C., Dzeja, P. P. & Herrmann, J., Jan 1 2018, (Accepted/In press) In : EBioMedicine.

Research output: Contribution to journalArticle

22 Scopus citations

Kir6.2 is required for adaptation to stress

Zingman, L. V., Hodgson, D. M., Bast, P. H., Kane, G. M., Terzic, C. M., Gumina, R. J., Pucar, D., Bienengraeber, M., Dzeja, P. P., Miki, T., Seino, S., Alekseev, A. E. & Terzic, A., Oct 1 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 20, p. 13278-13283 6 p.

Research output: Contribution to journalArticle

248 Scopus citations

Knockout of Kir6.2 negates ischemic preconditioning-induced protection of myocardial energetics

Gumina, R. J., Pucar, D., Bast, P., Hodgson, D. M., Kurtz, C. E., Dzeja, P. P., Miki, T., Seino, S. & Terzic, A., Jun 1 2003, In : American Journal of Physiology - Heart and Circulatory Physiology. 284, 6 53-6

Research output: Contribution to journalArticle

118 Scopus citations