Petras P Dzeja, PhD

  • 6237 Citations
  • 40 Scopus h-Index
1980 …2019

Research output per year

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Research Output

1980

Changes in energy transduction efficiency in mitochondria isolated from ischemic myocardium.

Toleikis, A., Dzeja, P. P. & Praskevicius, A., 1980, In : Advances in myocardiology. 2, p. 327-337 11 p.

Research output: Contribution to journalArticle

1 Scopus citations
1985

The effect of adenylate kinase activity on the rate and efficiency of energy transport from mitochondria to hexokinase

Dzeja, P. P., Kalvenas, A., Toleikis, A. & Praskevicius, A., 1985, In : Biochemistry International. 10, 2, p. 259-265 7 p.

Research output: Contribution to journalArticle

30 Scopus citations
1988

Functional alterations in the mitochondrial site of adenylate kinase and creatine kinase energy transport systems induced by myocardial ischemia and adriblastin

Toleikis, A. J., Kalvenas, A. A., Dzeja, P. P., Praskevicius, A. K. & Jasaitis, A. A., 1988, In : Biokhimiya. 53, 4

Research output: Contribution to journalArticle

9 Scopus citations
1990

Changes in adenylate kinase isozyme activity in the ischemic rabbit heart

Vitkevicius, K. T. & Dzeja, P. P., Aug 1990, In : Bulletin of Experimental Biology and Medicine. 110, 2, p. 1039-1040 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Effect of elemental sulphur on the activity of adenylate kinase and performance of isolated rabbit heart

Dagys, A. I., Vitkevicius, K. T., Balciunas, G. A., Gendviliene, V. I., Dzeja, P. P. & Toleikis, A. I., 1990, In : Byulleten Eksperimentalnoi Biologii i Meditsiny. 108, 10, p. 377-379 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Effect of elementary sulfur on adenylate kinase activity and working of the isolated rabbit heart

Dagys, A. I., Vitkevičius, K. T., Balčiunas, G. A., Gendviliene, V. I., Dzeja, P. P. & Toleikis, A. I., Oct 1990, In : Bulletin of Experimental Biology and Medicine. 110, 4, p. 1355-1357 3 p.

Research output: Contribution to journalArticle

1995

Adenylate kinase-catalyzed phosphoryl transfer couples ATP utilization with its generation by glycolysis in intact muscle

Zeleznikar, R. J., Dzeja, P. P. & Goldberg, N. D., 1995, In : Journal of Biological Chemistry. 270, 13, p. 7311-7319 9 p.

Research output: Contribution to journalArticle

102 Scopus citations
1996

Suppression of creatine kinase-catalyzed phosphotransfer results in increased phosphoryl transfer by adenylate kinase in intact skeletal muscle

Dzeja, P. P., Zeleznikar, R. J. & Goldberg, N. D., 1996, In : Journal of Biological Chemistry. 271, 22, p. 12847-12851 5 p.

Research output: Contribution to journalArticle

81 Scopus citations
1998

Adenylate kinase: Kinetic behavior in intact cells indicates it is integral to multiple cellular processes

Dzeja, P. P., Zeleznikar, R. J. & Goldberg, N. D., 1998, In : Molecular and Cellular Biochemistry. 184, 1-2, p. 169-182 14 p.

Research output: Contribution to journalArticle

119 Scopus citations

Mitochondrial ATP-sensitive K+ channels modulate cardiac mitochondrial function

Holmuhamedov, E. L., Jovanović, S., Dzeja, P. P., Jovanović, A. & Terzic, A., Nov 1998, In : American Journal of Physiology - Heart and Circulatory Physiology. 44, 5

Research output: Contribution to journalArticle

317 Scopus citations

Phosphotransfer reactions in the regulation of ATP-sensitive K+ channels

Dzeja, P. P. & Terzic, A., 1998, In : FASEB Journal. 12, 7, p. 523-529 7 p.

Research output: Contribution to journalArticle

128 Scopus citations
1999

Adenylate kinase-catalyzed phosphotransfer in the myocardium: Increased contribution in heart failure

Dzeja, P. P., Vitkevicius, K. T., Redfield, M. M., Burnett, J. C. J. & Terzic, A., May 28 1999, In : Circulation Research. 84, 10, p. 1137-1143 7 p.

Research output: Contribution to journalArticle

159 Scopus citations
40 Scopus citations

Structural plasticity of the cardiac nuclear pore complex in response to regulators of nuclear import

Terzic, C. M., Gacy, A. M., Bortolon, R., Dzeja, P. P., Puceat, M., Jaconi, M., Prendergast, F. G. & Terzic, A., Jun 11 1999, In : Circulation Research. 84, 11, p. 1292-1301 10 p.

Research output: Contribution to journalArticle

47 Scopus citations
2000

Adenylate kinase 1 gene deletion disrupts muscle energetic economy despite metabolic rearrangement

Janssen, E., Dzeja, P. P., Oerlemans, F., Simonetti, A. W., Heerschap, A., De Haan, A., Rush, P. S., Terjung, R. R., Wieringa, B. & Terzic, A., Dec 1 2000, In : EMBO Journal. 19, 23, p. 6371-6381 11 p.

Research output: Contribution to journalArticle

111 Scopus citations

ATPase activity of the sulfonylurea receptor: A catalytic function for the K(ATP) channel complex

Bienengraeber, M., Alekseev, A. E., Abraham, M. R., Carrasco, A. J., Moreau, C., Vivaudou, M., Dzeja, P. P. & Terzic, A., 2000, In : FASEB Journal. 14, 13, p. 1943-1952 10 p.

Research output: Contribution to journalArticle

124 Scopus citations

Compromised energetics in the adenylate kinase AK1 gene knockout heart under metabolic stress

Pucar, D., Janssen, E., Dzeja, P. P., Juranic, N., Macura, S. I., Wieringa, B. & Terzic, A., Dec 29 2000, In : Journal of Biological Chemistry. 275, 52, p. 41424-41429 6 p.

Research output: Contribution to journalArticle

68 Scopus citations

Failing energetics in failing hearts

Dzeja, P. P., Redfield, M. M., Burnett, J. C. J. & Terzic, A., 2000, In : Current Cardiology Reports. 2, 3, p. 212-217 6 p.

Research output: Contribution to journalArticle

86 Scopus citations

Mitochondrial K(ATP) channels: Probing molecular identity and pharmacology

Terzic, A., Dzeja, P. P. & Holmuhamedov, E. L., 2000, In : Journal of Molecular and Cellular Cardiology. 32, 11, p. 1911-1915 5 p.

Research output: Contribution to journalArticle

21 Scopus citations
2001

Adenylate kinase phosphotransfer communicates cellular energetic signals to ATP-sensitive potassium channels

Carrasco, A. J., Dzeja, P. P., Alekseev, A. E., Pucar, D., Zingman, L. V., Abraham, M. R., Hodgson, D., Bienengraeber, M., Puceat, M., Janssen, E., Wieringa, B. & Terzic, A., Jun 19 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 13, p. 7623-7628 6 p.

Research output: Contribution to journalArticle

201 Scopus citations

ATPase of the sulfonylurea receptor and KATP channel gating

Zingman, L. V., Alekseev, A. E., Bienengraeber, M., Dzeja, P. P. & Terzic, A., 2001, In : Clinical Pharmacology and Therapeutics. 69, 2

Research output: Contribution to journalArticle

Cellular energetics in the preconditioned state: Protective role for phosphotransfer reactions captured by 18O-assisted 31P NMR

Pucar, D., Dzeja, P. P., Bast, P., Juranic, N., Macura, S. I. & Terzic, A., Nov 30 2001, In : Journal of Biological Chemistry. 276, 48, p. 44812-44819 8 p.

Research output: Contribution to journalArticle

76 Scopus citations

Directed Inhibition of Nuclear Import in Cellular Hypertrophy

Terzic, C. M., Gacy, A. M., Bortolon, R., Dzeja, P. P., Puceat, M., Jaconi, M., Prendergast, F. G. & Terzic, A., Jun 8 2001, In : Journal of Biological Chemistry. 276, 23, p. 20566-20571 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Mitochondria: Gateway for cytoprotection

Dzeja, P. P., Holmuhamedov, E. L., Ozcan, C., Pucar, D., Jahangir, A. & Terzic, A., Oct 26 2001, In : Circulation Research. 89, 9, p. 744-746 3 p.

Research output: Contribution to journalArticle

43 Scopus citations

Signaling in channel/enzyme multimers: ATPase transitions in SUR module gate ATP-sensitive K + conductance

Zingman, L. V., Alekseev, A. E., Bienengraeber, M., Hodgson, D., Karger, A. B., Dzeja, P. P. & Terzic, A., Aug 2 2001, In : Neuron. 31, 2, p. 233-245 13 p.

Research output: Contribution to journalArticle

165 Scopus citations
2002

Adenylate kinase AK1 knockout heart: Energetics and functional performance under ischemia-reperfusion

Pucar, D., Bast, P., Gumina, R. J., Lim, L., Drahl, C., Juranic, N., Macura, S. I., Janssen, E., Wieringa, B., Terzic, A. & Dzeja, P. P., 2002, In : American Journal of Physiology - Heart and Circulatory Physiology. 283, 2 52-2

Research output: Contribution to journalArticle

48 Scopus citations

Coupling of cell energetics with membrane metabolic sensing: Integrative signaling through creatine kinase phosphotransfer disrupted by M-CK gene knock-out

Roselle Abraham, M., Selivanov, V. A., Hodgson, D. M., Pucar, D., Zingman, L. V., Wieringa, B., Dzeja, P. P., Alekseev, A. E. & Terzic, A., Jul 5 2002, In : Journal of Biological Chemistry. 277, 27, p. 24427-24434 8 p.

Research output: Contribution to journalArticle

126 Scopus citations

Energetic communication between mitochondria and nucleus directed by catalyzed phosphotransfer

Dzeja, P. P., Bortolon, R., Terzic, C. M., Holmuhamedov, E. L. & Terzic, A., Jul 23 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 15, p. 10156-10161 6 p.

Research output: Contribution to journalArticle

117 Scopus citations

Kir6.2 is required for adaptation to stress

Zingman, L. V., Hodgson, D. M., Bast, P. H., Kane, G. M., Terzic, C. M., Gumina, R. J., Pucar, D., Bienengraeber, M., Dzeja, P. P., Miki, T., Seino, S., Alekseev, A. E. & Terzic, A., Oct 1 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 20, p. 13278-13283 6 p.

Research output: Contribution to journalArticle

248 Scopus citations
186 Scopus citations
2003

Adenylate kinase 1 deficiency induces molecular and structural adaptations to support muscle energy metabolism

Janssen, E., De Groof, A., Wijers, M., Fransen, J., Dzeja, P. P., Terzic, A. & Wieringa, B., Apr 11 2003, In : Journal of Biological Chemistry. 278, 15, p. 12937-12945 9 p.

Research output: Contribution to journalArticle

35 Scopus citations
82 Scopus citations

Impaired intracellular energetic communication in muscles from creatine kinase and adenylate kinase (M-CK/AK1) double knock-out mice

Janssen, E., Terzic, A., Wieringa, B. & Dzeja, P. P., Aug 15 2003, In : Journal of Biological Chemistry. 278, 33, p. 30441-30449 9 p.

Research output: Contribution to journalArticle

51 Scopus citations

Knockout of Kir6.2 negates ischemic preconditioning-induced protection of myocardial energetics

Gumina, R. J., Pucar, D., Bast, P., Hodgson, D. M., Kurtz, C. E., Dzeja, P. P., Miki, T., Seino, S. & Terzic, A., Jun 1 2003, In : American Journal of Physiology - Heart and Circulatory Physiology. 284, 6 53-6

Research output: Contribution to journalArticle

118 Scopus citations

Phosphotransfer networks and cellular energetics

Dzeja, P. P. & Terzic, A., Jun 2003, In : Journal of Experimental Biology. 206, 12, p. 2039-2047 9 p.

Research output: Contribution to journalArticle

349 Scopus citations

Targeting nucleotide-requiring enzymes: Implications for diazoxide-induced cardioprotection

Dzeja, P. P., Bast, P., Ozcan, C., Valverde, A., Holmuhamedov, E. L., Van Wylen, D. G. L. & Terzic, A., Apr 1 2003, In : American Journal of Physiology - Heart and Circulatory Physiology. 284, 4 53-4

Research output: Contribution to journalArticle

88 Scopus citations
2004

ATP-sensitive K+ channel knockout compromises the metabolic benefit of exercise training, resulting in cardiac deficits

Kane, G. M., Behfar, A., Yamada, S., Terzic, C. M., O'Cochlain, F., Reyes, S., Dzeja, P. P., Miki, T., Seino, S. & Terzic, A., Dec 2004, In : Diabetes. 53, SUPPL. 3

Research output: Contribution to journalArticle

88 Scopus citations
12 Scopus citations

Mapping hypoxia-induced bioenergetic rearrangement and metabolic signalling by 18O-assisted 31P NMR and 1 NMR spectroscopy

Pucar, D., Dzeja, P. P., Bast, P., Gumina, R. J., Drahl, C., Lim, L., Juranic, N., Macura, S. I. & Terzic, A., Jan 2004, In : Molecular and Cellular Biochemistry. 256-257, 1-2, p. 281-289 9 p.

Research output: Contribution to journalArticle

34 Scopus citations
84 Scopus citations

Phosphotransfer dynamics in skeletal muscle from creatine kinase gene-deleted mice

Dzeja, P. P., Terzic, A. & Wieringa, B., Jan 2004, In : Molecular and Cellular Biochemistry. 256-257, 1-2, p. 13-27 15 p.

Research output: Contribution to journalArticle

53 Scopus citations
2006
16 Scopus citations

Cardiac system bioenergetics: Metabolic basis of the frank-starling law

Saks, V., Dzeja, P. P., Schlattner, U., Vendelin, M., Terzic, A. & Wallimann, T., Mar 2006, In : Journal of Physiology. 571, 2, p. 253-273 21 p.

Research output: Contribution to journalArticle

179 Scopus citations
2007

Defective metabolic signaling in adenylate kinase AK1 gene knock-out hearts compromises post-ischemic coronary reflow

Dzeja, P. P., Bast, P., Pucar, D., Wieringa, B. & Terzic, A., Oct 26 2007, In : Journal of Biological Chemistry. 282, 43, p. 31366-31372 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Integrated and Organized Cellular Energetic Systems: Theories of Cell Energetics, Compartmentation, and Metabolic Channeling

Saks, V., Monge, C., Anmann, T. & Dzeja, P. P., Nov 22 2007, Molecular System Bioenergetics: Energy for Life. Wiley-VCH Verlag GmbH & Co. KGaA, p. 59-109 51 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

25 Scopus citations

Integration of Adenylate Kinase and Glycolytic and Glycogenolytic Circuits in Cellular Energetics

Dzeja, P. P., Chung, S. & Terzic, A., Nov 22 2007, Molecular System Bioenergetics: Energy for Life. Wiley-VCH Verlag GmbH & Co. KGaA, p. 265-301 37 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

31 Scopus citations
302 Scopus citations

Mitochondria-nucleus energetic communication: Role for phosphotransfer networks in processing cellular information

Dzeja, P. P. & Terzic, A., 2007, Handbook of Neurochemistry and Molecular Neurobiology: Brain Energetics. Integration of Molecular and Cellular Processes. Springer US, p. 641-666 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Scopus citations

System Analysis of Cardiac Energetics-Excitation-Contraction Coupling: Integration of Mitochondrial Respiration, Phosphotransfer Pathways, Metabolic Pacing, and Substrate Supply in the Heart

Saks, V., Dzeja, P. P., Guzun, R., Aliev, M. K., Vendelin, M., Terzic, A. & Wallimann, T., Nov 22 2007, Molecular System Bioenergetics: Energy for Life. Wiley-VCH Verlag GmbH & Co. KGaA, p. 367-405 39 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Scopus citations
2008

Developmental restructuring of the creatine kinase system integrates mitochondrial energetics with stem cell cardiogenesis

Chung, S., Dzeja, P. P., Faustino, R. S. & Terzic, A., Dec 2008, Annals of the New York Academy of Sciences. Vol. 1147. p. 254-263 10 p. (Annals of the New York Academy of Sciences; vol. 1147).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

30 Scopus citations