Peizhou Jiang, MS, PhD

  • 506 Citations
  • 11 Scopus h-Index
20022018

Research output per year

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Research Output

  • 506 Citations
  • 11 Scopus h-Index
  • 27 Article
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Article
2017

Impaired endo-lysosomal membrane integrity accelerates the seeding progression of α-synuclein aggregates

Jiang, P., Gan, M., Yen, S. H., McLean, P. J. & Dickson, D. W., Dec 1 2017, In : Scientific Reports. 7, 1, 7690.

Research output: Contribution to journalArticle

18 Scopus citations

Parkinson’s disease: experimental models and reality

Jiang, P. & Dickson, D. W., Nov 18 2017, (Accepted/In press) In : Acta Neuropathologica. p. 1-20 20 p.

Research output: Contribution to journalArticle

32 Scopus citations
2016

Genetic modification of H2AX renders mesenchymal stromal cell–derived dopamine neurons more resistant to DNA damage and subsequent apoptosis

Jiang, P., Huang, P., Yen, S. H., Zubair, A. & Dickson, D. W., Dec 1 2016, In : Cytotherapy. 18, 12, p. 1483-1492 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Histones facilitate α-synuclein aggregation during neuronal apoptosis

Jiang, P., Gan, M., Yen, S. H., McLean, P. J. & Dickson, D. W., Dec 21 2016, (Accepted/In press) In : Acta Neuropathologica. p. 1-12 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Proaggregant nuclear factor(s) trigger rapid formation of α-synuclein aggregates in apoptotic neurons

Jiang, P., Gan, M., Yen, S. H., Moussaud, S., McLean, P. J. & Dickson, D. W., Jul 1 2016, In : Acta neuropathologica. 132, 1, p. 77-91 15 p.

Research output: Contribution to journalArticle

9 Scopus citations
2015

Extracellular ATP induces intracellular alpha-synuclein accumulation via P2X1 receptor-mediated lysosomal dysfunction

Gan, M., Moussaud, S., Jiang, P. & McLean, P. J., Feb 1 2015, In : Neurobiology of aging. 36, 2, p. 1209-1220 12 p.

Research output: Contribution to journalArticle

16 Scopus citations
2014
15 Scopus citations

Nutrient deprivation induces α-synuclein aggregation through endoplasmic reticulum stress response and SREBP2 pathway

Jiang, P., Gan, M., Lin, W. L. & Yen, S. H. C., 2014, In : Frontiers in Aging Neuroscience. 6, OCT, 268.

Research output: Contribution to journalArticle

16 Scopus citations
2013

Adenosine monophosphate-activated protein kinase overactivation leads to accumulation of α-synuclein oligomers and decrease of neurites

Jiang, P., Gan, M., Ebrahim, A. S., Castanedes-Casey, M., Dickson, D. W. & Yen, S. H. C., May 1 2013, In : Neurobiology of aging. 34, 5, p. 1504-1515 12 p.

Research output: Contribution to journalArticle

46 Scopus citations
11 Scopus citations
2010

ER stress response plays an important role in aggregation of -synuclein

Jiang, P., Gan, M., Ebrahim, A. S., Lin, W. L., Melrose, H. L. & Yen, S. H. C., Dec 15 2010, In : Molecular neurodegeneration. 5, 1, 56.

Research output: Contribution to journalArticle

52 Scopus citations
2008

Cathepsin D is the main lysosomal enzyme involved in the degradation of α-synuclein and generation of its carboxy-terminally truncated species

Sevlever, D., Jiang, P. & Yen, S. H. C., Sep 9 2008, In : Biochemistry. 47, 36, p. 9678-9687 10 p.

Research output: Contribution to journalArticle

161 Scopus citations

Using leucine zipper to facilitate α-synuclein assembly

Jiang, P., Ko, L. W., Jansen, K. R., Golde, T. E. & Yen, S. H., Sep 1 2008, In : FASEB Journal. 22, 9, p. 3165-3174 10 p.

Research output: Contribution to journalArticle

7 Scopus citations
2007

Oxidative stress-induced phosphorylation, degradation and aggregation of α-synuclein are linked to upregulated CK2 and cathepsin D

Takahashi, M., Ko, L. W., Kulathingal, J., Jiang, P., Sevlever, D. & Yen, S. H. C., Aug 1 2007, In : European Journal of Neuroscience. 26, 4, p. 863-874 12 p.

Research output: Contribution to journalArticle

81 Scopus citations
2005

A modified method of nuclear transfer for investigating early development of mouse embryos reconstructed with cumulus cell nuclei

Shen, X. M., Qiao, G. L., Jiang, P. Z., Li, X., Huang, H. & Yao, K. T., Jun 2005, In : Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA. 25, 6, p. 613-618 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
1 Scopus citations

Proteome analysis of antiproliferative mechanism of 12-O- tetradecanoylphorbol 13-acetate on cultured nasopharyngeal carcinoma CNE2 cells

Jiang, P., Gan, M., Huang, H., Shen, X., Wang, S. & Yao, K., Mar 1 2005, In : Journal of Proteome Research. 4, 2, p. 599-605 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Proteomics-based identification of proteins with altered expression induced by 12-O-tetradecanoylphorbol 13-acetate in nasopharyngeal carcinoma CNE2 cells

Jiang, P. Z., Gan, M., Huang, H., Shen, X. M., Wang, S. & Yao, K. T., Feb 1 2005, In : Acta Biochimica et Biophysica Sinica. 37, 2, p. 97-106 10 p.

Research output: Contribution to journalArticle

11 Scopus citations
2004
2003

Establishment of transgenic mouse models carrying human polymeric immunoglobulin receptor gene

Lü, L. C., He, Y., Lan, K., Shen, X. M., Huang, H., Jiang, P. Z., Wang, S., Xu, S. J. & Yao, K. T., Feb 2003, In : Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA. 23, 2, p. 127-129 3 p.

Research output: Contribution to journalArticle

2002

Construction of transgenic mice carrying enhanced green fluorescent protein gene by seminiferous tubule microinjection.

Shen, X. M., Qiao, G. L., Zhang, L., Jiang, P. Z., Huang, H. & Yao, K. T., Mar 2002, In : Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA. 22, 3, p. 250-253 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Establishment of transgenic Xenopus laevis by intracytoplasmic sperm injection

Jiang, P. Z., Feng, X. L., Huang, H., Shen, X. M., Shi, J. L. & Yao, K. T., Aug 2002, In : Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA. 22, 8, p. 673-677 5 p.

Research output: Contribution to journalArticle

1 Scopus citations
1 Scopus citations

Rapid isolation of cancer cells from tumor tissue by micromanuiplator and extraction of tiny amount of RNA.

Jiang, P. Z., Shen, X. M., Huang, H., Shi, Y. M. & Yao, K. T., Jun 2002, In : Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA. 22, 6, p. 551-553 3 p.

Research output: Contribution to journalArticle

2 Scopus citations