Noralane Morey Lindor, MD

  • 18858 Citations
  • 66 h-Index
1992 …2019
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Research Output 1992 2019

2019
4 Citations (Scopus)

Discovery of common and rare genetic risk variants for colorectal cancer

Huyghe, J. R., Bien, S. A., Harrison, T. A., Kang, H. M., Chen, S., Schmit, S. L., Conti, D. V., Qu, C., Jeon, J., Edlund, C. K., Greenside, P., Wainberg, M., Schumacher, F. R., Smith, J. D., Levine, D. M., Nelson, S. C., Sinnott-Armstrong, N. A., Albanes, D., Alonso, M. H., Anderson, K. & 179 othersArnau-Collell, C., Arndt, V., Bamia, C., Banbury, B. L., Baron, J. A., Berndt, S. I., Bézieau, S., Bishop, D. T., Boehm, J., Boeing, H., Brenner, H., Brezina, S., Buch, S., Buchanan, D. D., Burnett-Hartman, A., Butterbach, K., Caan, B. J., Campbell, P. T., Carlson, C. S., Castellví-Bel, S., Chan, A. T., Chang-Claude, J., Chanock, S. J., Chirlaque, M. D., Cho, S. H., Connolly, C. M., Cross, A. J., Cuk, K., Curtis, K. R., de la Chapelle, A., Doheny, K. F., Duggan, D., Easton, D. F., Elias, S. G., Elliott, F., English, D. R., Feskens, E. J. M., Figueiredo, J. C., Fischer, R., FitzGerald, L. M., Forman, D., Gala, M., Gallinger, S., Gauderman, W. J., Giles, G. G., Gillanders, E., Gong, J., Goodman, P. J., Grady, W. M., Grove, J. S., Gsur, A., Gunter, M. J., Haile, R. W., Hampe, J., Hampel, H., Harlid, S., Hayes, R. B., Hofer, P., Hoffmeister, M., Hopper, J. L., Hsu, W. L., Huang, W. Y., Hudson, T. J., Hunter, D. J., Ibañez-Sanz, G., Idos, G. E., Ingersoll, R., Jackson, R. D., Jacobs, E. J., Jenkins, M. A., Joshi, A. D., Joshu, C. E., Keku, T. O., Key, T. J., Kim, H. R., Kobayashi, E., Kolonel, L. N., Kooperberg, C., Kühn, T., Küry, S., Kweon, S. S., Larsson, S. C., Laurie, C. A., Le Marchand, L., Leal, S. M., Lee, S. C., Lejbkowicz, F., Lemire, M., Li, C. I., Li, L., Lieb, W., Lin, Y., Lindblom, A., Lindor, N. M., Ling, H., Louie, T. L., Männistö, S., Markowitz, S. D., Martín, V., Masala, G., McNeil, C. E., Melas, M., Milne, R. L., Moreno, L., Murphy, N., Myte, R., Naccarati, A., Newcomb, P. A., Offit, K., Ogino, S., Onland-Moret, N. C., Pardini, B., Parfrey, P. S., Pearlman, R., Perduca, V., Pharoah, P. D. P., Pinchev, M., Platz, E. A., Prentice, R. L., Pugh, E., Raskin, L., Rennert, G., Rennert, H. S., Riboli, E., Rodríguez-Barranco, M., Romm, J., Sakoda, L. C., Schafmayer, C., Schoen, R. E., Seminara, D., Shah, M., Shelford, T., Shin, M. H., Shulman, K., Sieri, S., Slattery, M. L., Southey, M. C., Stadler, Z. K., Stegmaier, C., Su, Y. R., Tangen, C. M., Thibodeau, S. N., Thomas, D. C., Thomas, S. S., Toland, A. E., Trichopoulou, A., Ulrich, C. M., Van Den Berg, D. J., van Duijnhoven, F. J. B., Van Guelpen, B., van Kranen, H., Vijai, J., Visvanathan, K., Vodicka, P., Vodickova, L., Vymetalkova, V., Weigl, K., Weinstein, S. J., White, E., Win, A. K., Wolf, C. R., Wolk, A., Woods, M. O., Wu, A. H., Zaidi, S. H., Zanke, B. W., Zhang, Q., Zheng, W., Scacheri, P. C., Potter, J. D., Bassik, M. C., Kundaje, A., Casey, G., Moreno, V., Abecasis, G. R., Nickerson, D. A., Gruber, S. B., Hsu, L. & Peters, U., Jan 1 2019, In : Nature Genetics. 51, 1, p. 76-87 12 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Long Noncoding RNA
Preclinical Drug Evaluations
Genome-Wide Association Study
Haplotypes
1 Citation (Scopus)

Shared heritability and functional enrichment across six solid cancers

Jiang, X., Finucane, H. K., Schumacher, F. R., Schmit, S. L., Tyrer, J. P., Han, Y., Michailidou, K., Lesseur, C., Kuchenbaecker, K. B., Dennis, J., Conti, D. V., Casey, G., Gaudet, M. M., Huyghe, J. R., Albanes, D., Aldrich, M. C., Andrew, A. S., Andrulis, I. L., Anton-Culver, H., Antoniou, A. C. & 313 othersAntonenkova, N. N., Arnold, S. M., Aronson, K. J., Arun, B. K., Bandera, E. V., Barkardottir, R. B., Barnes, D. R., Batra, J., Beckmann, M. W., Benitez, J., Benlloch, S., Berchuck, A., Berndt, S. I., Bickeböller, H., Bien, S. A., Blomqvist, C., Boccia, S., Bogdanova, N. V., Bojesen, S. E., Bolla, M. K., Brauch, H., Brenner, H., Brenton, J. D., Brook, M. N., Brunet, J., Brunnström, H., Buchanan, D. D., Burwinkel, B., Butzow, R., Cadoni, G., Caldés, T., Caligo, M. A., Campbell, I., Campbell, P. T., Cancel-Tassin, G., Cannon-Albright, L., Campa, D., Caporaso, N., Carvalho, A. L., Chan, A. T., Chang-Claude, J., Chanock, S. J., Chen, C., Christiani, D. C., Claes, K. B. M., Claessens, F., Clements, J., Collée, J. M., Correa, M. C., Couch, F. J., Cox, A., Cunningham, J. M., Cybulski, C., Czene, K., Daly, M. B., deFazio, A., Devilee, P., Diez, O., Gago-Dominguez, M., Donovan, J. L., Dörk, T., Duell, E. J., Dunning, A. M., Dwek, M., Eccles, D. M., Edlund, C. K., Edwards, D. R. V., Ellberg, C., Evans, D. G., Fasching, P. A., Ferris, R. L., Liloglou, T., Figueiredo, J. C., Fletcher, O., Fortner, R. T., Fostira, F., Franceschi, S., Friedman, E., Gallinger, S. J., Ganz, P. A., Garber, J., García-Sáenz, J. A., Gayther, S. A., Giles, G. G., Godwin, A. K., Goldberg, M. S., Goldgar, D. E., Goode, E. L., Goodman, M. T., Goodman, G., Grankvist, K., Greene, M. H., Gronberg, H., Gronwald, J., Guénel, P., Håkansson, N., Hall, P., Hamann, U., Hamdy, F. C., Hamilton, R. J., Hampe, J., Haugen, A., Heitz, F., Herrero, R., Hillemanns, P., Hoffmeister, M., Høgdall, E., Hong, Y. C., Hopper, J. L., Houlston, R., Hulick, P. J., Hunter, D. J., Huntsman, D. G., Idos, G., Imyanitov, E. N., Ingles, S. A., Isaacs, C., Jakubowska, A., James, P., Jenkins, M. A., Johansson, M., Johansson, M., John, E. M., Joshi, A. D., Kaneva, R., Karlan, B. Y., Kelemen, L. E., Kühl, T., Khaw, K. T., Khusnutdinova, E., Kibel, A. S., Kiemeney, L. A., Kim, J., Kjaer, S. K., Knight, J. A., Kogevinas, M., Kote-Jarai, Z., Koutros, S., Kristensen, V. N., Kupryjanczyk, J., Lacko, M., Lam, S., Lambrechts, D., Landi, M. T., Lazarus, P., Le, N. D., Lee, E., Lejbkowicz, F., Lenz, H. J., Leslie, G., Lessel, D., Lester, J., Levine, D. A., Li, L., Li, C. I., Lindblom, A., Lindor, N. M., Liu, G., Loupakis, F., Lubiński, J., Maehle, L., Maier, C., Mannermaa, A., Marchand, L. L., Margolin, S., May, T., McGuffog, L., Meindl, A., Middha, P., Miller, A., Milne, R. L., MacInnis, R. J., Modugno, F., Montagna, M., Moreno, V., Moysich, K. B., Mucci, L., Muir, K., Mulligan, A. M., Nathanson, K. L., Neal, D. E., Ness, A. R., Neuhausen, S. L., Nevanlinna, H., Newcomb, P. A., Newcomb, L. F., Nielsen, F. C., Nikitina-Zake, L., Nordestgaard, B. G., Nussbaum, R. L., Offit, K., Olah, E., Olama, A. A. A., Olopade, O. I., Olshan, A. F., Olsson, H., Osorio, A., Pandha, H., Park, J. Y., Pashayan, N., Parsons, M. T., Pejovic, T., Penney, K. L., Peters, W. H. M., Phelan, C. M., Phipps, A. I., Plaseska-Karanfilska, D., Pring, M., Prokofyeva, D., Radice, P., Stefansson, K., Ramus, S. J., Raskin, L., Rennert, G., Rennert, H. S., van Rensburg, E. J., Riggan, M. J., Risch, H. A., Risch, A., Roobol, M. J., Rosenstein, B. S., Rossing, M. A., De Ruyck, K., Saloustros, E., Sandler, D. P., Sawyer, E. J., Schabath, M. B., Schleutker, J., Schmidt, M. K., Setiawan, V. W., Shen, H., Siegel, E. M., Sieh, W., Singer, C. F., Slattery, M. L., Sorensen, K. D., Southey, M. C., Spurdle, A. B., Stanford, J. L., Stevens, V. L., Stintzing, S., Stone, J., Sundfeldt, K., Sutphen, R., Swerdlow, A. J., Tajara, E. H., Tangen, C. M., Tardon, A., Taylor, J. A., Teare, M. D., Teixeira, M. R., Terry, M. B., Terry, K. L., Thibodeau, S. N., Thomassen, M., Bjørge, L., Tischkowitz, M., Toland, A. E., Torres, D., Townsend, P. A., Travis, R. C., Tung, N., Tworoger, S. S., Ulrich, C. M., Usmani, N., Vachon, C. M., Van Nieuwenhuysen, E., Vega, A., Aguado-Barrera, M. E., Wang, Q., Webb, P. M., Weinberg, C. R., Weinstein, S., Weissler, M. C., Weitzel, J. N., West, C. M. L., White, E., Whittemore, A. S., Wichmann, H. E., Wiklund, F., Winqvist, R., Wolk, A., Woll, P., Woods, M., Wu, A. H., Wu, X., Yannoukakos, D., Zheng, W., Zienolddiny, S., Ziogas, A., Zorn, K. K., Lane, J. M., Saxena, R., Thomas, D., Hung, R. J., Diergaarde, B., McKay, J., Peters, U., Hsu, L., García-Closas, M., Eeles, R. A., Chenevix-Trench, G., Brennan, P. J., Haiman, C. A., Simard, J., Easton, D. F., Gruber, S. B., Pharoah, P. D. P., Price, A. L., Pasaniuc, B., Amos, C. I., Kraft, P. & Lindström, S., Dec 1 2019, In : Nature Communications. 10, 1, 431.

Research output: Contribution to journalArticle

cancer
Nucleic Acid Regulatory Sequences
Tumors
Neoplasms
Genes
2018
11 Citations (Scopus)

Assessment of the Clinical Relevance of BRCA2 Missense Variants by Functional and Computational Approaches

Guidugli, L., Shimelis, H., Masica, D. L., Pankratz, V. S., Lipton, G. B., Singh, N., Hu, C., Monteiro, A. N. A., Lindor, N. M., Goldgar, D. E., Karchin, R., Iversen, E. S. & Couch, F. J., Jan 1 2018, (Accepted/In press) In : American Journal of Human Genetics.

Research output: Contribution to journalArticle

Virulence
Homologous Recombination
Endophenotypes
Recombinational DNA Repair
DNA
1 Citation (Scopus)
genetic research
Genetic Research
Spouses
research results
spouse
2 Citations (Scopus)

Cohort Profile: The Colon Cancer Family Registry Cohort (CCFRC)

Colon Cancer Family Registry Cohort Investigators , Apr 1 2018, In : International Journal of Epidemiology. 47, 2

Research output: Contribution to journalArticle

Medical History Taking
Preschool Children
New Zealand
Colonic Neoplasms
Canada

Comprehensive annotation of BRCA1 and BRCA2 missense variants by functionally validated sequence-based computational prediction models

Hart, S., Hoskin, T., Shimelis, H., Moore, R. M., Feng, B., Thomas, A., Lindor, N. M., Polley, E., Goldgar, D. E., Iversen, E., Monteiro, A. N. A., Suman, V. J. & Couch, F. J., Jun 8 2018, (Accepted/In press) In : Genetics in Medicine. p. 1-10 10 p.

Research output: Contribution to journalArticle

Politics
Computer Simulation
Area Under Curve
BRCA2 Protein
Confidence Intervals

Current Approaches to Cancer Genetic Counseling Services for Spanish-Speaking Patients

Augusto, B., Kasting, M. L., Couch, F. J., Lindor, N. M. & Vadaparampil, S. T., Jun 7 2018, (Accepted/In press) In : Journal of Immigrant and Minority Health. p. 1-4 4 p.

Research output: Contribution to journalArticle

Genetic Services
Genetic Counseling
Hispanic Americans
Neoplasms
Communication Barriers

Developing a Process for Returning Medically Actionable Genomic Variants to Latino Patients in a Federally Qualified Health Center

Shaibi, G. Q., Kullo, I. J., Singh, D. P., Sharp, R. R., De Filippis, E. A., Cuellar, I., Hernandez, V., Levey, S., Radecki Breitkopf, C., Olson, J. E., Cerhan, J. R., Mandarino, L. J., Thibodeau, S. N. & Lindor, N. M., Jan 1 2018, (Accepted/In press) In : Public Health Genomics.

Research output: Contribution to journalArticle

Hyperlipidemias
Hispanic Americans
Community Health Planning
Clinical Decision Support Systems
Community Health Centers
2 Citations (Scopus)

DNA mismatch repair protein deficient non-neoplastic colonic crypts: a novel indicator of Lynch syndrome

Pai, R., Dudley, B., Karloski, E., Brand, R. E., O’Callaghan, N., Rosty, C., Buchanan, D. D., Jenkins, M. A., Thibodeau, S. N., French, A. J., Lindor, N. M. & Pai, R. K., Jun 8 2018, (Accepted/In press) In : Modern Pathology. p. 1-11 11 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
DNA Mismatch Repair
Colorectal Neoplasms
Proteins
Protein Deficiency
4 Citations (Scopus)

Evidence-based assessments of clinical actionability in the context of secondary findings: Updates from ClinGen's Actionability Working Group

on behalf of the ClinGen Resource, Nov 1 2018, In : Human Mutation. 39, 11, p. 1677-1685 9 p.

Research output: Contribution to journalArticle

Genomics
Medical Genetics
Decision Support Techniques
Practice Guidelines
Genes

Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies

Pande, M., Joon, A., Brewster, A. M., Chen, W. V., Hopper, J. L., Eng, C., Shete, S., Casey, G., Schumacher, F., Lin, Y., Harrison, T. A., White, E., Ahsan, H., Andrulis, I. L., Whittemore, A. S., John, E. M., Win, A. K., Makalic, E., Schmidt, D. F., Kapuscinski, M. K. & 8 othersOchs-Balcom, H. M., Gallinger, S., Jenkins, M. A., Newcomb, P. A., Lindor, N. M., Peters, U., Amos, C. I. & Lynch, P. M., Apr 1 2018, In : PLoS One. 13, 4, e0196245.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Genetic Predisposition to Disease
colorectal neoplasms
Genetic Markers
breast neoplasms
2 Citations (Scopus)

Interaction between polymorphisms in aspirin metabolic pathways, regular aspirin use and colorectal cancer risk: A case-control study in unselected white European populations

Sheth, H., Northwood, E., Ulrich, C. M., Scherer, D., Elliott, F., Barrett, J. H., Forman, D., Roland Wolf, C., Smith, G., Jackson, M. S., Santibanez-Koref, M., Haile, R., Casey, G., Jenkins, M., Win, A. K., Hopper, J. L., Le Marchand, L., Lindor, N. M., Thibodeau, S. N., Potter, J. D. & 2 othersBurn, J. & Timothy Bishop, D., Feb 1 2018, In : PLoS One. 13, 2, e0192223.

Research output: Contribution to journalArticle

aspirin
Metabolic Networks and Pathways
case-control studies
Polymorphism
colorectal neoplasms

Leptin gene variants and colorectal cancer risk: Sex-specific associations

Chun, K. A., Kocarnik, J. M., Hardikar, S. S., Robinson, J. R., Berndt, S. I., Chan, A. T., Figueiredo, J. C., Lindor, N. M., Song, M., Schoen, R. E., Hayes, R. B., Potter, J. D., Nassir, R., Bézieau, S., Marchand, L. L., Slattery, M. L., White, E., Peters, U. & Newcomb, P. A., Oct 1 2018, In : PLoS One. 13, 10, e0206519.

Research output: Contribution to journalArticle

Leptin
leptin
colorectal neoplasms
Colorectal Neoplasms
Genes
21 Citations (Scopus)

Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations

EMBRACE, GEMO Study Collaborators & HEBON, May 1 2018, In : Human Mutation. 39, 5, p. 593-620 28 p.

Research output: Contribution to journalArticle

Mutation
Population
Research Personnel
Germ-Line Mutation
Genetic Testing

Physical activity and the risk of colorectal cancer in Lynch syndrome

Dashti, S. G., Win, A. K., Hardikar, S. S., Glombicki, S. E., Mallenahalli, S., Thirumurthi, S., Peterson, S. K., You, Y. N., Buchanan, D. D., Figueiredo, J. C., Campbell, P. T., Gallinger, S., Newcomb, P. A., Potter, J. D., Lindor, N. M., Le Marchand, L., Haile, R. W., Hopper, J. L., Jenkins, M. A., Basen-Engquist, K. M. & 2 othersLynch, P. M. & Pande, M., Jan 1 2018, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Colorectal Neoplasms
Metabolic Equivalent
DNA Mismatch Repair
Colonic Neoplasms
2 Citations (Scopus)

Pragmatic tools for sharing genomic research results with the relatives of living and deceased research participants

Wolf, S. M., Scholtes, E., Koenig, B. A., Petersen, G. M., Berry, S. A., Beskow, L. M., Daly, M. B., Fernandez, C. V., Green, R. C., Leroy, B. S., Lindor, N. M., O’Rourke, P., Radecki Breitkopf, C., Rothstein, M. A., Ness, B. V. & Wilfond, B. S., Jan 1 2018, In : Journal of Law, Medicine and Ethics. 46, 1, p. 87-109 23 p.

Research output: Contribution to journalComment/debate

Research
Consensus
Consent Forms
Organized Financing
Information Storage and Retrieval
3 Citations (Scopus)

The Return of Actionable Variants Empirical (RAVE) Study, a Mayo Clinic Genomic Medicine Implementation Study: Design and Initial Results

Kullo, I. J., Olson, J. E., Fan, X., Jose, M., Safarova, M., Radecki Breitkopf, C., Winkler, E., Kochan, D. C., Snipes, S., Pacyna, J. E., Carney, M., Chute, C. G., Gupta, J., Jose, S., Venner, E., Murugan, M., Jiang, Y., Zordok, M., Farwati, M., Philogene, M. & 7 othersSmith, E., Shaibi, G. Q., Caraballo, P., Freimuth, R., Lindor, N. M., Sharp, R. R. & Thibodeau, S. N., Nov 1 2018, In : Mayo Clinic Proceedings. 93, 11, p. 1600-1610 11 p.

Research output: Contribution to journalArticle

Medicine
Electronic Health Records
Genes
Cardiovascular Diseases
Penetrance
2017
5 Citations (Scopus)

Alcohol consumption and the risk of colorectal cancer for mismatch repair gene mutation carriers

Ghazaleh Dashti, S., Buchanan, D. D., Jayasekara, H., Ouakrim, D. A., Clendenning, M., Rosty, C., Winship, I. M., MacRae, F. A., Giles, G. G., Parry, S., Casey, G., Haile, R. W., Gallinger, S., Le Marchand, L., Thibodeau, S. N., Lindor, N. M., Newcomb, P. A., Potter, J. D., Baron, J. A., Hopper, J. L. & 2 othersJenkins, M. A. & Win, A. K., Mar 1 2017, In : Cancer Epidemiology Biomarkers and Prevention. 26, 3, p. 366-375 10 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Alcohol Drinking
Colorectal Neoplasms
Mutation
Genes

Clinical verification of genetic results returned to research participants: findings from a Colon Cancer Family Registry

Laurino, M. Y., Truitt, A. R., Tenney, L., Fisher, D., Lindor, N. M., Veenstra, D., Jarvik, G. P., Newcomb, P. A. & Fullerton, S. M., Jan 1 2017, In : Molecular Genetics and Genomic Medicine. 5, 6, p. 700-708 9 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Registries
Genetic Research
Research
Research Personnel
4 Citations (Scopus)

From the laboratory to the clinic: sharing BRCA VUS reclassification tools with practicing genetics professionals

Augusto, B. M., Lake, P., Scherr, C. L., Couch, F. J., Lindor, N. M. & Vadaparampil, S. T., Nov 9 2017, (Accepted/In press) In : Journal of Community Genetics. p. 1-7 7 p.

Research output: Contribution to journalArticle

Patient Education
Research
Counselors
Postcards
3 Citations (Scopus)

Germline miRNA DNA variants and the risk of colorectal cancer by subtype

Lindor, N. M., Larson, M. C., DeRycke, M. S., McDonnell, S. K., Baheti, S., Fogarty, Z. C., Win, A. K., Potter, J. D., Buchanan, D. D., Clendenning, M., Newcomb, P. A., Casey, G., Gallinger, S., Le Marchand, L., Hopper, J. L., Jenkins, M. A., Goode, E. L. & Thibodeau, S. N., Mar 1 2017, In : Genes Chromosomes and Cancer. 56, 3, p. 177-184 8 p.

Research output: Contribution to journalArticle

MicroRNAs
Colorectal Neoplasms
DNA
DNA Mismatch Repair
Neoplasms
4 Citations (Scopus)

Long-term weight loss after colorectal cancer diagnosis is associated with lower survival: The Colon Cancer Family Registry

Kocarnik, J. M., Hua, X., Hardikar, S., Robinson, J., Lindor, N. M., Win, A. K., Hopper, J. L., Figueiredo, J. C., Potter, J. D., Campbell, P. T., Gallinger, S., Cotterchio, M., Adams, S. V., Cohen, S. A., Phipps, A. I. & Newcomb, P. A., 2017, (Accepted/In press) In : Cancer.

Research output: Contribution to journalArticle

Colonic Neoplasms
Registries
Weight Loss
Colorectal Neoplasms
Weights and Measures
12 Citations (Scopus)

Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer

Rodriguez-Broadbent, H., Law, P. J., Sud, A., Palin, K., Tuupanen, S., Gylfe, A., Hänninen, U. A., Cajuso, T., Tanskanen, T., Kondelin, J., Kaasinen, E., Sarin, A. P., Ripatti, S., Eriksson, J. G., Rissanen, H., Knekt, P., Pukkala, E., Jousilahti, P., Salomaa, V., Palotie, A. & 36 othersRenkonen-Sinisalo, L., Lepistö, A., Böhm, J., Mecklin, J. P., Al-Tassan, N. A., Palles, C., Martin, L., Barclay, E., Farrington, S. M., Timofeeva, M. N., Meyer, B. F., Wakil, S. M., Campbell, H., Smith, C. G., Idziaszczyk, S., Maughan, T. S., Kaplan, R., Kerr, R., Kerr, D., Passarelli, M. N., Figueiredo, J. C., Buchanan, D. D., Win, A. K., Hopper, J. L., Jenkins, M. A., Lindor, N. M., Newcomb, P. A., Gallinger, S., Conti, D., Schumacher, F., Casey, G., Aaltonen, L. A., Cheadle, J. P., Tomlinson, I. P., Dunlop, M. G. & Houlston, R. S., Jun 15 2017, In : International Journal of Cancer. 140, 12, p. 2701-2708 8 p.

Research output: Contribution to journalArticle

Random Allocation
Hyperlipidemias
Colorectal Neoplasms
Confidence Intervals
Odds Ratio
63 Citations (Scopus)

Molecular biomarkers for the evaluation of colorectal cancer: Guideline from The American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and the American Society of Clinical Oncology

Sepulveda, A. R., Hamilton, S. R., Allegra, C. J., Grody, W., Cushman-Vokoun, A. M., Funkhouser, W. K., Kopetz, S. E., Lieu, C., Lindor, N. M., Minsky, B. D., Monzon, F. A., Sargent, D. J., Singh, V. M., Willis, J., Clark, J., Colasacco, C., Rumble, R. B., Temple-Smolkin, R., Ventura, C. B. & Nowak, J. A., May 1 2017, In : Journal of Clinical Oncology. 35, 13, p. 1453-1496 44 p.

Research output: Contribution to journalArticle

Molecular Pathology
Colorectal Neoplasms
Biomarkers
Guidelines
Epidermal Growth Factor Receptor
8 Citations (Scopus)

Molecular biomarkers for the evaluation of colorectal cancer: Guideline from the American society for clinical pathology, college of American pathologists, association for molecular pathology, and American society of clinical oncology

Sepulveda, A. R., Hamilton, S. R., Allegra, C. J., Grody, W., Cushman-Vokoun, A. M., Funkhouser, W. K., Kopetz, S. E., Lieu, C., Lindor, N. M., Minsky, B. D., Monzon, F. A., Sargent, D. J., Singh, V. M., Willis, J., Clark, J., Colasacco, C., Bryan Rumble, R., Temple-Smolkin, R., Ventura, C. B. & Nowak, J. A., May 1 2017, In : Archives of Pathology and Laboratory Medicine. 141, 5, p. 625-657 33 p.

Research output: Contribution to journalArticle

Clinical Pathology
Medical Oncology
Molecular Pathology
Colorectal Neoplasms
Biomarkers
2 Citations (Scopus)

Molecular biomarkers for the evaluation of colorectal cancer: Guideline summary from the American society for clinical pathology, college of American pathologists, association for molecular pathology, and American society of clinical oncology

Sepulveda, A. R., Hamilton, S. R., Allegra, C. J., Grody, W., Cushman-Vokoun, A. M., Funkhouser, W. K., Kopetz, S. E., Lieu, C., Lindor, N. M., Minsky, B. D., Monzon, F. A., Sargent, D. J., Singh, V. M., Willis, J., Clark, J., Colasacco, C., Rumble, R. B., Temple-Smolkin, R., Ventura, C. B. & Nowak, J. A., May 1 2017, In : Journal of Oncology Practice. 13, 5, p. 333-337 5 p.

Research output: Contribution to journalArticle

Clinical Pathology
Medical Oncology
Molecular Pathology
Colorectal Neoplasms
Biomarkers
20 Citations (Scopus)

Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and American Society of Clinical Oncology

Sepulveda, A. R., Hamilton, S. R., Allegra, C. J., Grody, W., Cushman-Vokoun, A. M., Funkhouser, W. K., Kopetz, S. E., Lieu, C., Lindor, N. M., Minsky, B. D., Monzon, F. A., Sargent, D. J., Singh, V. M., Willis, J., Clark, J., Colasacco, C., Rumble, R. B., Temple-Smolkin, R., Ventura, C. B. & Nowak, J. A., Mar 1 2017, In : Journal of Molecular Diagnostics. 19, 2, p. 187-225 39 p.

Research output: Contribution to journalReview article

Molecular Pathology
Colorectal Neoplasms
Biomarkers
Epidermal Growth Factor Receptor
Guidelines
3 Citations (Scopus)

Molecular Biomarkers for the Evaluation of Colorectal Cancer

Sepulveda, A. R., Hamilton, S. R., Allegra, C. J., Grody, W., Cushman-Vokoun, A. M., Funkhouser, W. K., Kopetz, S. E., Lieu, C., Lindor, N. M., Minsky, B. D., Monzon, F. A., Sargent, D. J., Singh, V. M., Willis, J., Clark, J., Colasacco, C., Rumble, R. B., Temple-Smolkin, R., Ventura, C. B. & Nowak, J. A., Mar 1 2017, In : American Journal of Clinical Pathology. 147, 3, p. 221-260 40 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Biomarkers
Epidermal Growth Factor Receptor
Guidelines
Molecular Pathology
4 Citations (Scopus)

Non-BRCA familial breast cancer: review of reported pathology and molecular findings

Keeney, M. G., Couch, F. J., Visscher, D. W. & Lindor, N. M., Jun 1 2017, In : Pathology. 49, 4, p. 363-370 8 p.

Research output: Contribution to journalArticle

Molecular Pathology
Breast Neoplasms
Hereditary Neoplastic Syndromes
Genes
Neoplasm Genes
40 Citations (Scopus)

Prevalence and penetrance of major genes and polygenes for colorectal cancer

Win, A. K., Jenkins, M. A., Dowty, J. G., Antoniou, A. C., Lee, A., Giles, G. G., Buchanan, D. D., Clendenning, M., Rosty, C., Ahnen, D. J., Thibodeau, S. N., Casey, G., Gallinger, S., Le Marchand, L., Haile, R. W., Potter, J. D., Zheng, Y., Lindor, N. M., Newcomb, P. A., Hopper, J. L. & 1 othersMacInnis, R. J., Mar 1 2017, In : Cancer Epidemiology Biomarkers and Prevention. 26, 3, p. 404-412 9 p.

Research output: Contribution to journalArticle

Penetrance
Colorectal Neoplasms
Genes
Mutation
DNA Mismatch Repair
20 Citations (Scopus)

Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis

May-Wilson, S., Sud, A., Law, P. J., Palin, K., Tuupanen, S., Gylfe, A., Hänninen, U. A., Cajuso, T., Tanskanen, T., Kondelin, J., Kaasinen, E., Sarin, A. P., Eriksson, J. G., Rissanen, H., Knekt, P., Pukkala, E., Jousilahti, P., Salomaa, V., Ripatti, S., Palotie, A. & 34 othersRenkonen-Sinisalo, L., Lepistö, A., Böhm, J., Mecklin, J. P., Al-Tassan, N. A., Palles, C., Farrington, S. M., Timofeeva, M. N., Meyer, B. F., Wakil, S. M., Campbell, H., Smith, C. G., Idziaszczyk, S., Maughan, T. S., Fisher, D., Kerr, R., Kerr, D., Passarelli, M. N., Figueiredo, J. C., Buchanan, D. D., Win, A. K., Hopper, J. L., Jenkins, M. A., Lindor, N. M., Newcomb, P. A., Gallinger, S., Conti, D., Schumacher, F., Casey, G., Aaltonen, L. A., Cheadle, J. P., Tomlinson, I. P., Dunlop, M. G. & Houlston, R. S., Oct 1 2017, In : European Journal of Cancer. 84, p. 228-238 11 p.

Research output: Contribution to journalArticle

Mendelian Randomization Analysis
Colorectal Neoplasms
Fatty Acids
Monounsaturated Fatty Acids
Dietary Fats
6 Citations (Scopus)

Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes

DeRycke, M. S., Gunawardena, S., Balcom, J. R., Pickart, A. M., Waltman, L. A., French, A. J., McDonnell, S., Riska, S. M., Fogarty, Z. C., Larson, M. C., Middha, S., Eckloff, B. W., Asmann, Y., Ferber, M. J., Haile, R. W., Gallinger, S., Clendenning, M., Rosty, C., Win, A. K., Buchanan, D. D. & 6 othersHopper, J. L., Newcomb, P. A., Le Marchand, L., Goode, E. L., Lindor, N. M. & Thibodeau, S. N., Jan 1 2017, In : Molecular Genetics and Genomic Medicine. 5, 5, p. 553-569 17 p.

Research output: Contribution to journalArticle

Neoplasm Genes
Colorectal Neoplasms
DNA Mismatch Repair
Genes
Mutation
3 Citations (Scopus)

Targeted sequencing of established and candidate colorectal cancer genes in the Colon Cancer Family Registry Cohort

Colon Cancer Family Registry (CCFR), Nov 1 2017, In : Oncotarget. 8, 55, p. 93450-93463 14 p.

Research output: Contribution to journalArticle

Neoplasm Genes
Colonic Neoplasms
Registries
Colorectal Neoplasms
Germ-Line Mutation
19 Citations (Scopus)

Timing of aspirin and other nonsteroidal anti-inflammatory drug use among patients with colorectal cancer in relation to tumor markers and survival

Hua, X., Phipps, A. I., Burnett-Hartman, A. N., Adams, S. V., Hardikar, S., Cohen, S. A., Kocarnik, J. M., Ahnen, D. J., Lindor, N. M., Baron, J. A. & Newcomb, P. A., Aug 20 2017, In : Journal of Clinical Oncology. 35, 24, p. 2806-2813 8 p.

Research output: Contribution to journalArticle

Tumor Biomarkers
Aspirin
Colorectal Neoplasms
Anti-Inflammatory Agents
Survival
17 Citations (Scopus)

Whole-Genome Sequencing in Healthy People

Lindor, N. M., Thibodeau, S. N. & Burke, W., Jan 1 2017, In : Mayo Clinic Proceedings. 92, 1, p. 159-172 14 p.

Research output: Contribution to journalReview article

Genome
Inborn Genetic Diseases
Genetic Testing
Ethics
Delivery of Health Care
2016
6 Citations (Scopus)

Association of a let-7 miRNA binding region of TGFBR1 with hereditary mismatch repair proficient colorectal cancer (MSS HNPCC)

Xicola, R. M., Bontu, S., Doyle, B. J., Rawson, J., Garre, P., Lee, E., De la Hoya, M., Bessa, X., Clofent, J., Bujanda, L., Balaguer, F., Castellví-Bel, S., Alenda, C., Jover, R., Ruiz-Ponte, C., Syngal, S., Andreu, M., Carracedo, A., Castells, A., Newcomb, P. A. & 6 othersLindor, N. M., Potter, J. D., Baron, J. A., Ellis, N. A., Caldes, T. & Lor, X. L., Aug 1 2016, In : Carcinogenesis. 37, 8, p. 751-758 8 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
MicroRNAs
Microsatellite Repeats
Colorectal Neoplasms
3' Untranslated Regions
43 Citations (Scopus)

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170

Dunning, A. M., Michailidou, K., Kuchenbaecker, K. B., Thompson, D., French, J. D., Beesley, J., Healey, C. S., Kar, S., Pooley, K. A., Lopez-Knowles, E., Dicks, E., Barrowdale, D., Sinnott-Armstrong, N. A., Sallari, R. C., Hillman, K. M., Kaufmann, S., Sivakumaran, H., Marjaneh, M. M., Lee, J. S., Hills, M. & 228 othersJarosz, M., Drury, S., Canisius, S., KBolla, M., Dennis, J., Wang, Q., LHopper, J., Southey, M. C., Broeks, A., Schmidt, M. K., Lophatananon, A., Muir, K., Beckmann, M. W., Fasching, P. A., Dos-Santos-Silva, I., Peto, J., Sawyer, E. J., Tomlinson, I., Burwinkel, B., Marme, F., Guénel, P., Truong, T., Bojesen, S. E., Flyger, H., Gonzlez-Neira, A., Perez, J. I. A., Anton-Culver, H., Eunjung, L., Arndt, V., Brenner, H., Meindl, A., Schmutzler, R. K., Brauch, H., Hamann, U., Aittomki, K., Blomqvist, C., Ito, H., Matsuo, K., Bogdanova, N., Dörk, T., Lindblom, A., Margolin, S., Kosma, V. M., Mannermaa, A., Tseng, C. C., Wu, A. H., Lambrechts, D., Wildiers, H., Chang-Claude, J., Rudolph, A., Peterlongo, P., Radice, P., Olson, J. E., GGiles, G., Milne, R. L., Haiman, C. A., Henderson, B. E., Goldberg, M. S., Teo, S. H., Yip, C. H., Nord, S., Borresen-Dale, A. L., Kristensen, V., Long, J., Zheng, W., Pylks, K., Winqvist, R., Andrulis, I. L., Knight, J. A., Devilee, P., Seynaeve, C., Figueroa, J., Sherman, M. E., Czene, K., Darabi, H., Hollestelle, A., Van Den Ouweland, A. M. W., Humphreys, K., Gao, Y. T., Shu, X. O., Cox, A., Cross, S. S., Blot, W., Cai, Q., Ghoussaini, M., Perkins, B. J., Shah, M., Choi, J. Y., Kang, D., Lee, S. C., Hartman, M., Kabisch, M., Torres, D., Jakubowska, A., Lubinski, J., Brennan, P., Sangrajrang, S., Ambrosone, C. B., Toland, A. E., Shen, C. Y., Wu, P. E., Orr, N., Swerdlow, A., McGuffog, L., Healey, S., Lee, A., Kapuscinski, M., John, E. M., Terry, M. B., Daly, M. B., Goldgar, D. E., Buys, S. S., Janavicius, R., Tihomirova, L., Tung, N., Dorfling, C. M., Van Rensburg, E. J., Neuhausen, S. L., Ejlertsen, B., OHansen, T. V., Osorio, A., Benitez, J., Rando, R., Weitzel, J. N., Bonanni, B., Peissel, B., Manoukian, S., Papi, L., Ottini, L., Konstantopoulou, I., Apostolou, P., Garber, J., Rashid, M. U., Frost, D., Izatt, L., Ellis, S., Godwin, A. K., Arnold, N., Niederacher, D., Rhiem, K., Bogdanova-Markov, N., Sagne, C., Stoppa-Lyonnet, D., Damiola, F., Sinilnikova, O. M., Mazoyer, S., Isaacs, C., MClaes, K. B., De Leeneer, K., De La Hoya, M., Caldes, T., Nevanlinna, H., Khan, S., Mensenkamp, A. R., Hooning, M. J., Rookus, M. A., Kwong, A., Olah, E., Diez, O., Brunet, J., Pujana, M. A., Gronwald, J., Huzarski, T., Barkardottir, R. B., Laframboise, R., Soucy, P., Montagna, M., Agata, S., Teixeira, M. R., Kyung Park, S., Lindor, N. M., Couch, F. J., Tischkowitz, M., Foretova, L., Vijai, J., Offit, K., Singer, C. F., Rappaport, C., MPhelan, C., Greene, M. H., Mai, P. L., Rennert, G., Imyanitov, E. N., Hulick, P. J., Phillips, K. A., Piedmonte, M., Mulligan, A. M., Glendon, G., Bojesen, A., Thomassen, M., Caligo, M. A., Yoon, S. Y., Friedman, E., Laitman, Y., Borg, A., Von Wachenfeldt, A., Ehrencrona, H., Rantala, J., Olopade, O. I., Ganz, P. A., Nussbaum, R. L., Gayther, S. A., LNathanson, K., Domchek, S. M., Arun, B. K., Mitchell, G., Karlan, B. Y., Lester, J., Maskarinec, G., Woolcott, C., Scott, C., Stone, J., Apicella, C., Tamimi, R., Luben, R., Khaw, K. T., Helland, S., Haakensen, V., Dowsett, M., Pharoah, P. D. P., Simard, J., Hall, P., Garca-Closas, M., Vachon, C. M., Chenevix-Trench, G., Antoniou, A. C., Easton, D. F. & Edwards, S. L., Mar 29 2016, In : Nature Genetics. 48, 4, p. 374-386 13 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Phenotype
Estrogen Receptors
Transcriptional Silencer Elements
Alleles
3 Citations (Scopus)

Cholecystectomy and the risk of colorectal cancer by tumor mismatch repair deficiency status

Shang, J., Reece, J. C., Buchanan, D. D., Giles, G. G., Figueiredo, J. C., Casey, G., Gallinger, S., Thibodeau, S. N., Lindor, N. M., Newcomb, P. A., Potter, J. D., Baron, J. A., Hopper, J. L., Jenkins, M. A. & Win, A. K., Aug 1 2016, In : International Journal of Colorectal Disease. 31, 8, p. 1451-1457 7 p.

Research output: Contribution to journalArticle

Cholecystectomy
Colorectal Neoplasms
DNA Mismatch Repair
Registries
Neoplasms
11 Citations (Scopus)

Clinicopathologic risk factor distributions for MLH1 promoter region methylation in CIMP-positive tumors

Levine, A. J., Phipps, A. I., Baron, J. A., Buchanan, D. D., Ahnen, D. J., Cohen, S. A., Lindor, N. M., Newcomb, P. A., Rosty, C., Haile, R. W., Laird, P. W. & Weisenberger, D. J., Jan 1 2016, In : Cancer Epidemiology Biomarkers and Prevention. 25, 1, p. 68-75 8 p.

Research output: Contribution to journalArticle

CpG Islands
Genetic Promoter Regions
Methylation
Phenotype
Neoplasms
13 Citations (Scopus)

Comparison of Prediction Models for Lynch Syndrome among Individuals with Colorectal Cancer

Lynch Syndrome prediction model validation study group, Feb 1 2016, In : Journal of the National Cancer Institute. 108, 2, djv308.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Colorectal Neoplasms
Mutation
Population
Area Under Curve
24 Citations (Scopus)

Cross-cancer genome-wide analysis of lung, ovary, breast, prostate, and colorectal cancer reveals novel pleiotropic associations

Colorectal Transdisciplinary (CORECT) Study, Ovarian Cancer Association Consortium (OCAC), The PRACTICAL Consortium, Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON), African American Breast Cancer Consortium (AABC) & African Ancestry Prostate Cancer Consortium (AAPC), Sep 1 2016, In : Cancer Research. 76, 17, p. 5103-5114 12 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Colorectal Neoplasms
Lung Neoplasms
Prostatic Neoplasms
Genome
9 Citations (Scopus)

CYP24A1 variant modifies the association between use of oestrogen plus progestogen therapy and colorectal cancer risk

Garcia-Albeniz, X., Rudolph, A., Hutter, C., White, E., Lin, Y., Rosse, S. A., Figueiredo, J. C., Harrison, T. A., Jiao, S., Brenner, H., Casey, G., Hudson, T. J., Thornquist, M., Le Marchand, L., Potter, J., Slattery, M. L., Zanke, B., Baron, J. A., Caan, B. J., Chanock, S. J. & 36 othersBerndt, S. I., Stelling, D., Fuchs, C. S., Hoffmeister, M., Butterbach, K., Du, M., James Gauderman, W., Gunter, M. J., Lemire, M., Ogino, S., Lin, J., Hayes, R. B., Haile, R. W., Schoen, R. E., Warnick, G. S., Jenkins, M. A., Thibodeau, S. N., Schumacher, F. R., Lindor, N. M., Kolonel, L. N., Hopper, J. L., Gong, J., Seminara, D., Pflugeisen, B. M., Ulrich, C. M., Qu, C., Duggan, D., Cotterchio, M., Campbell, P. T., Carlson, C. S., Newcomb, P. A., Giovannucci, E., Hsu, L., Chan, A. T., Peters, U. & Chang-Claude, J., Jan 19 2016, In : British Journal of Cancer. 114, 2, p. 221-229 9 p.

Research output: Contribution to journalArticle

Progestins
Colorectal Neoplasms
Estrogens
Hormones
Therapeutics
3 Citations (Scopus)

Estimating cumulative risks for breast cancer for carriers of variants in uncommon genes

Lindor, N. M., Hopper, J. & Dowty, J., Mar 9 2016, (Accepted/In press) In : Familial Cancer. p. 1-4 4 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Genes
Penetrance
Health Personnel
Counseling
3 Citations (Scopus)

Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

Vigorito, E., Kuchenbaecker, K. B., Beesley, J., Adlard, J., Agnarsson, B. A., Andrulis, I. L., Arun, B. K., Barjhoux, L., Belotti, M., Benitez, J., Berger, A., Bojesen, A., Bonanni, B., Brewer, C., Caldes, T., Caligo, M. A., Campbell, I., Chan, S. B., Claes, K. B. M., Cohn, D. E. & 126 othersCook, J., Daly, M. B., Damiola, F., Davidson, R., Pauw, A. D., Delnatte, C., Diez, O., Domchek, S. M., Dumont, M., Durda, K., Dworniczak, B., Easton, D. F., Eccles, D., Edwinsdotter Ardnor, C., Eeles, R., Ejlertsen, B., Ellis, S., Evans, D. G., Feliubadalo, L., Fostira, F., Foulkes, W. D., Friedman, E., Frost, D., Gaddam, P., Ganz, P. A., Garber, J., Garcia-Barberan, V., Gauthier-Villars, M., Gehrig, A., Gerdes, A. M., Giraud, S., Godwin, A. K., Goldgar, D. E., Hake, C. R., Hansen, T. V. O., Healey, S., Hodgson, S., Hogervorst, F. B. L., Houdayer, C., Hulick, P. J., Imyanitov, E. N., Isaacs, C., Izatt, L., Izquierdo, A., Jacobs, L., Jakubowska, A., Janavicius, R., Jaworska-Bieniek, K., Jensen, U. B., John, E. M., Vijai, J., Karlan, B. Y., Kast, K., Investigators, KC. F., Khan, S., Kwong, A., Laitman, Y., Lester, J., Lesueur, F., Liljegren, A., Lubinski, J., Mai, P. L., Manoukian, S., Mazoyer, S., Meindl, A., Mensenkamp, A. R., Montagna, M., Nathanson, K. L., Neuhausen, S. L., Nevanlinna, H., Niederacher, D., Olah, E., Olopade, O. I., Ong, K. R., Osorio, A., Park, S. K., Paulsson-Karlsson, Y., Pedersen, I. S., Peissel, B., Peterlongo, P., Pfeiler, G., Phelan, C. M., Piedmonte, M., Poppe, B., Pujana, M. A., Radice, P., Rennert, G., Rodriguez, G. C., Rookus, M. A., Ross, E. A., Schmutzler, R. K., Simard, J., Singer, C. F., Slavin, T. P., Soucy, P., Southey, M., Steinemann, D., Stoppa-Lyonnet, D., Sukiennicki, G., Sutter, C., Szabo, C. I., Tea, M. K., Teixeira, M. R., Teo, S. H., Terry, M. B., Thomassen, M., Tibiletti, M. G., Tihomirova, L., Tognazzo, S., van Rensburg, E. J., Varesco, L., Varon-Mateeva, R., Vratimos, A., Weitzel, J. N., McGuffog, L., Kirk, J., Toland, A. E., Hamann, U., Lindor, N. M., Ramus, S. J., Greene, M. H., Couch, F. J., Offit, K., Pharoah, P. D. P., Chenevix-Trench, G. & Antoniou, A. C., Jan 1 2016, In : PLoS One. 11, 7, p. e0158801

Research output: Contribution to journalArticle

ovarian neoplasms
Ovarian Neoplasms
mutation
Mutation
Single Nucleotide Polymorphism
11 Citations (Scopus)

Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer

CCFR and GECCO, Oct 1 2016, In : PLoS Genetics. 12, 10, e1006296.

Research output: Contribution to journalArticle

smoking
colorectal neoplasms
Alcohol Drinking
alcohol
Colorectal Neoplasms
17 Citations (Scopus)

Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the colon cancer family registry cohort

Rosty, C., Clendenning, M., Walsh, M. D., Eriksen, S. V., Southey, M. C., Winship, I. M., Macrae, F. A., Boussioutas, A., Poplawski, N. K., Parry, S., Arnold, J., Young, J. P., Casey, G., Haile, R. W., Gallinger, S., Le Marchand, L., Newcomb, P. A., Potter, J. D., Derycke, M., Lindor, N. M. & 6 othersThibodeau, S. N., Baron, J. A., Win, A. K., Hopper, J. L., Jenkins, M. A. & Buchanan, D. D., 2016, In : BMJ Open. 6, 2, e010293.

Research output: Contribution to journalArticle

Germ-Line Mutation
Colonic Neoplasms
Registries
Colorectal Neoplasms
Mutation
32 Citations (Scopus)

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

Couch, F. J., Kuchenbaecker, K. B., Michailidou, K., Mendoza-Fandino, G. A., Nord, S., Lilyquist, J., Olswold, C., Hallberg, E., Agata, S., Ahsan, H., Aittomäki, K., Ambrosone, C., Andrulis, I. L., Anton-Culver, H., Arndt, V., Arun, B. K., Arver, B., Barile, M., Barkardottir, R. B., Barrowdale, D. & 229 othersBeckmann, L., Beckmann, M. W., Benitez, J., Blank, S. V., Blomqvist, C., Bogdanova, N. V., Bojesen, S. E., Bolla, M. K., Bonanni, B., Brauch, H., Brenner, H., Burwinkel, B., Buys, S. S., Caldes, T., Caligo, M. A., Canzian, F., Carpenter, J., Chang-Claude, J., Chanock, S. J., Chung, W. K., Claes, K. B. M., Cox, A., Cross, S. S., Cunningham, J. M., Czene, K., Daly, M. B., Damiola, F., Darabi, H., De La Hoya, M., Devilee, P., Diez, O., Ding, Y. C., Dolcetti, R., Domchek, S. M., Dorfling, C. M., Dos-Santos-Silva, I., Dumont, M., Dunning, A. M., Eccles, D. M., Ehrencrona, H., Ekici, A. B., Eliassen, H., Ellis, S., Fasching, P. A., Figueroa, J., Flesch-Janys, D., Försti, A., Fostira, F., Foulkes, W. D., Friebel, T., Friedman, E., Frost, D., Gabrielson, M., Gammon, M. D., Ganz, P. A., Gapstur, S. M., Garber, J., Gaudet, M. M., Gayther, S. A., Gerdes, A. M., Ghoussaini, M., Giles, G. G., Glendon, G., Godwin, A. K., Goldberg, M. S., Goldgar, D. E., González-Neira, A., Greene, M. H., Gronwald, J., Guénel, P., Gunter, M., Haeberle, L., Haiman, C. A., Hamann, U., Hansen, T. V. O., Hart, S., Healey, S., Heikkinen, T., Henderson, B. E., Herzog, J., Hogervorst, F. B. L., Hollestelle, A., Hooning, M. J., Hoover, R. N., Hopper, J. L., Humphreys, K., Hunter, D. J., Huzarski, T., Imyanitov, E. N., Isaacs, C., Jakubowska, A., James, P., Janavicius, R., Jensen, U. B., John, E. M., Jones, M., Kabisch, M., Kar, S., Karlan, B. Y., Khan, S., Khaw, K. T., Kibriya, M. G., Knight, J. A., Ko, Y. D., Konstantopoulou, I., Kosma, V. M., Kristensen, V., Kwong, A., Laitman, Y., Lambrechts, D., Lazaro, C., Lee, E., Le Marchand, L., Lester, J., Lindblom, A., Lindor, N. M., Lindstrom, S., Liu, J., Long, J., Lubinski, J., Mai, P. L., Makalic, E., Malone, K. E., Mannermaa, A., Manoukian, S., Margolin, S., Marme, F., Martens, J. W. M., Mcguffog, L., Meindl, A., Miller, A., Milne, R. L., Miron, P., Montagna, M., Mazoyer, S., Mulligan, A. M., Muranen, T. A., Nathanson, K. L., Neuhausen, S. L., Nevanlinna, H., Nordestgaard, B. G., Nussbaum, R. L., Offit, K., Olah, E., Olopade, O. I., Olson, J. E., Osorio, A., Park, S. K., Peeters, P. H., Peissel, B., Peterlongo, P., Peto, J., Phelan, C. M., Pilarski, R., Poppe, B., Pylkäs, K., Radice, P., Rahman, N., Rantala, J., Rappaport, C., Rennert, G., Richardson, A., Robson, M., Romieu, I., Rudolph, A., Rutgers, E. J., Sanchez, M. J., Santella, R. M., Sawyer, E. J., Schmidt, D. F., Schmidt, M. K., Schmutzler, R. K., Schumacher, F., Scott, R., Senter, L., Sharma, P., Simard, J., Singer, C. F., Sinilnikova, O. M., Soucy, P., Southey, M., Steinemann, D., Stenmark-Askmalm, M., Stoppa-Lyonnet, D., Swerdlow, A., Szabo, C. I., Tamimi, R., Tapper, W., Teixeira, M. R., Teo, S. H., Terry, M. B., Thomassen, M., Thompson, D., Tihomirova, L., Toland, A. E., Tollenaar, R. A. E. M., Tomlinson, I., Truong, T., Tsimiklis, H., Teulé, A., Tumino, R., Tung, N., Turnbull, C., Ursin, G., Van Deurzen, C. H. M., Van Rensburg, E. J., Varon-Mateeva, R., Wang, Z., Wang-Gohrke, S., Weiderpass, E., Weitzel, J. N., Whittemore, A., Wildiers, H., Winqvist, R., Yang, X. R., Yannoukakos, D., Yao, S., Zamora, M. P., Zheng, W., Hall, P., Kraft, P., Vachon, C. M., Slager, S. L., Chenevix-Trench, G., Pharoah, P. D. P., Monteiro, A. A. N., García-Closas, M., Easton, D. F. & Antoniou, A. C., Apr 27 2016, In : Nature Communications. 7, 11375.

Research output: Contribution to journalArticle

estrogens
loci
breast
Estrogen Receptors
Genes
35 Citations (Scopus)

Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk

Zeng, C., Matsuda, K., Jia, W. H., Chang, J., Kweon, S. S., Xiang, Y. B., Shin, A., Jee, S. H., Kim, D. H., Zhang, B., Cai, Q., Guo, X., Long, J., Wang, N., Courtney, R., Pan, Z. Z., Wu, C., Takahashi, A., Shin, M. H., Matsuo, K. & 87 othersMatsuda, F., Gao, Y. T., Oh, J. H., Kim, S., Jung, K. J., Ahn, Y. O., Ren, Z., Li, H. L., Wu, J., Shi, J., Wen, W., Yang, G., Li, B., Ji, B. T., Gruber, S. B., Schumacher, F. R., Stenzel, S. L., Casey, G., Hopper, J. L., Jenkins, M. A., Kim, H. R., Jeong, J. Y., Park, J. W., Tajima, K., Cho, S. H., Kubo, M., Shu, X. O., Lin, D., Zeng, Y. X., Zheng, W., Brenner, H., Schoen, R. E., Küry, S., Baron, J. A., Berndt, S. I., Bezieau, S., Caan, B. J., Carlson, C. S., Chan, A. T., Chang-Claude, J., Chanock, S. J., Conti, D. V., Curtis, K., Duggan, D., Fuchs, C. S., Gallinger, S., Giovannucci, E. L., Haile, R. W., Harrison, T. A., Hayes, R. B., Hoffmeister, M., Hsu, L., Hudson, T. J., Hunter, D. J., Hutter, C. M., Jackson, R. D., Jiao, S., Le Marchand, L., Lemire, M., Lindor, N. M., Ma, J., Newcomb, P. A., Peters, U., Potter, J. D., Qu, C., Seminara, D., Slattery, M. L., Thibodeau, S. N., White, E., Zanke, B. W., Blalock, K., Campbell, P. T., Edlund, C. K., Figueiredo, J., Gauderman, W. J., Gong, J., Green, R. C., Harju, J. F., Jacobs, E. J., Li, L., Lin, Y., Manion, F. J., Moreno, V., Mukherjee, B., Raskin, L., Severi, G. & Thomas, D. C., Jun 1 2016, In : Gastroenterology. 150, 7, p. 1633-1645 13 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Genes
Prokaryotic Initiation Factor-3
Eukaryotic Initiation Factor-3
Eukaryotic Initiation Factors
12 Citations (Scopus)

Knowledge and Uptake of Genetic Counseling and Colonoscopic Screening Among Individuals at Increased Risk for Lynch Syndrome and their Endoscopists from the Family Health Promotion Project

Patel, S. G., Ahnen, D. J., Kinney, A. Y., Horick, N., Finkelstein, D. M., Hill, D. A., Lindor, N. M., MaCrae, F. & Lowery, J. T., Feb 9 2016, (Accepted/In press) In : American Journal of Gastroenterology.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Family Health
Genetic Counseling
Health Promotion
Genetic Testing
17 Citations (Scopus)

Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer

Jarvis, D., Mitchell, J. S., Law, P. J., Palin, K., Tuupanen, S., Gylfe, A., Hänninen, U. A., Cajuso, T., Tanskanen, T., Kondelin, J., Kaasinen, E., Sarin, A. P., Kaprio, J., Eriksson, J. G., Rissanen, H., Knekt, P., Pukkala, E., Jousilahti, P., Salomaa, V., Ripatti, S. & 37 othersPalotie, A., Järvinen, H., Renkonen-Sinisalo, L., Lepistö, A., Böhm, J., Meklin, J. P., Al-Tassan, N. A., Palles, C., Martin, L., Barclay, E., Farrington, S. M., Timofeeva, M. N., Meyer, B. F., Wakil, S. M., Campbell, H., Smith, C. G., Idziaszczyk, S., Maughan, T. S., Kaplan, R., Kerr, R., Kerr, D., Buchanan, D. D., Win, A. K., Hopper, J. L., Jenkins, M. A., Lindor, N. M., Newcomb, P. A., Gallinger, S., Conti, D., Schumacher, F., Casey, G., Taipale, J., Aaltonen, L. A., Cheadle, J. P., Dunlop, M. G., Tomlinson, I. P. & Houlston, R. S., Jul 12 2016, In : British Journal of Cancer. 115, 2, p. 266-272 7 p.

Research output: Contribution to journalArticle

Mendelian Randomization Analysis
Adiposity
Colorectal Neoplasms
Waist-Hip Ratio
Body Mass Index