• 27379 Citations
  • 94 Scopus h-Index
1973 …2020

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Article

Polycystic liver disease: The interplay of genes causative for hepatic and renal cystogenesis

Masyuk, T. V., Masyuk, A. I. & La Russo, N. F., Jun 1 2018, In : Hepatology. 67, 6, p. 2462-2464 3 p.

Research output: Contribution to journalArticle

Polycystic liver diseases: Advanced insights into the molecular mechanisms

Perugorria, M. J., Masyuk, T. V., Marin, J. J., Marzioni, M., Bujanda, L., La Russo, N. F. & Banales, J. M., Dec 11 2014, In : Nature Reviews Gastroenterology and Hepatology. 11, 12, p. 750-761 12 p.

Research output: Contribution to journalArticle

34 Scopus citations

Polymicrobial cholangitis and kaposi's sarcoma in blood product transfusion-related acquired immune deficiency syndrome

Cockerill, F. R., Hurley, D. V., Malagelada, J. R., Larusso, N. F., Edson, R. S., Katzmann, J. A., Banks, P. M., Wiltsie, J. C., Davis, J. P., Lack, E. E., Ishak, K. G. & Van Scoy, R. E., Jun 1986, In : The American Journal of Medicine. 80, 6, p. 1237-1241 5 p.

Research output: Contribution to journalArticle

29 Scopus citations

Pouchitis after ileal pouch-anal anastomosis for ulcerative colitis occurs with increased frequency in patients with associated primary sclerosing cholangitis

Penna, C., Dozois, R., Tremaine, W., Sandborn, W., LaRusso, N., Schleck, C. & Ilstrup, D., Jan 1 1996, In : Gut. 38, 2, p. 234-239 6 p.

Research output: Contribution to journalArticle

Open Access
405 Scopus citations

Primary sclerosing cholangitis: Natural history, prognostic factors and survival analysis

Wiesner, R. H., Grambsch, P. M., Dickson, E. R., Ludwig, J., Maccarty, R. L., Hunter, E. B., Fleming, T. R., Fisher, L. D., Beaver, S. J. & Larusso, N. F., Oct 1989, In : Hepatology. 10, 4, p. 430-436 7 p.

Research output: Contribution to journalArticle

490 Scopus citations

Primary sclerosing cholangitis: Findings on cholangiography and pancreatography

MacCarty, R. L., LaRusso, N. F., Wiesner, R. H. & Ludwig, J., Jan 1 1983, In : Radiology. 149, 1, p. 39-44 6 p.

Research output: Contribution to journalArticle

278 Scopus citations

Primary sclerosing cholangitis: A progressive disease?

Porayko, M. K., LaRusso, N. F. & Wiesner, R. H., Feb 1991, In : Seminars in Liver Disease. 11, 1, p. 18-25 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

Primary sclerosing cholangitis: Summary of a workshop

LaRusso, N. F., Shneider, B. L., Black, D., Gores, G. J., James, S. P., Doo, E. & Hoofnagle, J. H., Sep 1 2006, In : Hepatology. 44, 3, p. 746-764 19 p.

Research output: Contribution to journalArticle

202 Scopus citations

Primary sclerosing cholangitis: Refinement and validation of survival models

Dickson, E. R., Murtaugh, P. A., Wiesner, R. H., Grambsch, P. M., Fleming, T. R., Ludwig, J., LaRusso, N. F., Malinchoc, M., Chapman, R. W., Kaplan, M. M., Maddrey, W. C., Williams, R., Farrant, M. & Langworthy, A., Dec 1992, In : Gastroenterology. 103, 6, p. 1893-1901 9 p.

Research output: Contribution to journalArticle

224 Scopus citations

Primary sclerosing cholangitis

Ueno, Y. & LaRusso, N. F., Aug 1 1994, In : Journal of gastroenterology. 29, 4, p. 531-543 13 p.

Research output: Contribution to journalArticle

19 Scopus citations

Primary sclerosing cholangitis: Value of cholangiography in determining the prognosis

Craig, D. A., MacCarty, R. L., Wiesner, R. H., Grambsch, P. M. & LaRusso, N. F., Jan 1 1991, In : American Journal of Roentgenology. 157, 5, p. 959-964 6 p.

Research output: Contribution to journalArticle

62 Scopus citations

Primary Sclerosing Cholangitis

Dickson, E. R., Larusso, N. F. & Wiesner, R. H., Jan 1 1984, In : Hepatology. 4, 1 S, p. 33S-35S

Research output: Contribution to journalArticle

30 Scopus citations

Primary sclerosing cholangitis and celiac disease. A novel association

Hay, J. E., Wiesner, R. H., Shorter, R. G., LaRusso, N. F. & Baldus, W. P., Jan 1 1988, In : Annals of internal medicine. 109, 9, p. 713-717 5 p.

Research output: Contribution to journalArticle

115 Scopus citations

Primary Sclerosing Cholangitis Risk Estimate Tool (PREsTo) Predicts Outcomes of the Disease: A Derivation and Validation Study Using Machine Learning

Eaton, J. E., Vesterhus, M., McCauley, B. M., Atkinson, E. J., Schlicht, E. M., Juran, B. D., Gossard, A. A., La Russo, N. F., Gores, G. J., Karlsen, T. H. & Lazaridis, K. N., Jan 1 2019, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

8 Scopus citations

Primary sclerosing cholangitis with normal serum alkaline phosphatase activity

Balasubramaniam, K., Wiesner, R. H. & LaRusso, N. F., Nov 1988, In : Gastroenterology. 95, 5, p. 1395-1398 4 p.

Research output: Contribution to journalArticle

82 Scopus citations

Principles to promote physician satisfaction and work-life balance.

Shanafelt, T. D., West, C. P., Poland, G. A., LaRusso, N. F., Menaker, R. & Bahn, R. S., Dec 2008, In : Minnesota medicine. 91, 12, p. 41-43 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

Proceedings: Mechanism of action of chenodeoxycholic acid in gallstone dissolution.

Northfield, T. C., Larusso, N. F., Thistle, J. L. & Hofmann, A. F., Oct 1 1973, In : Gut. 14, 10, p. 826-827 2 p.

Research output: Contribution to journalArticle

7 Scopus citations
33 Scopus citations

Prospective randomized comparison of mezlocillin therapy alone with combined ampicillin and gentamicin therapy for patients with cholangitis

Gerecht, W. B., Henry, N. K., Hoffman, W. W., Muller, S. M., LaRusso, N. F., Rosenblatt, J. E. & Wilson, W. R., Jan 1 1989, In : Archives of internal medicine. 149, 6, p. 1279-1284 6 p.

Research output: Contribution to journalArticle

53 Scopus citations

Prospective trial of penicillamine in primary sclerosing cholangitis

LaRusso, N. F., Wiesner, R. H., Ludwig, J., MacCarty, R. L., Beaver, S. J. & Zinsmeister, A. R., Oct 1988, In : Gastroenterology. 95, 4, p. 1036-1042 7 p.

Research output: Contribution to journalArticle

141 Scopus citations
45 Scopus citations

Proteolytic cleavage and nuclear translocation of fibrocystin is regulated by intracellular Ca2+ and activation of protein kinase C

Hiesberger, T., Gourley, E., Erickson, A., Koulen, P., Ward, C. J., Masyuk, T. V., Larusso, N. F., Harris, P. C. & Igarashi, P., Nov 10 2006, In : Journal of Biological Chemistry. 281, 45, p. 34357-34364 8 p.

Research output: Contribution to journalArticle

56 Scopus citations

Purification and immunological quantification of rat liver lysosomal glycosidases

De Groen, P. C., LeSage, G. D., Tietz, P. S. & LaRusso, N. F., Jan 1 1989, In : Biochemical Journal. 264, 1, p. 115-123 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Purification and partial characterization of a heat-resistant, cytosolic neuropeptidase from rat liver

Janas, R. M., Marks, D. L. & LaRusso, N. F., Jan 31 1994, In : Biochemical and Biophysical Research Communications. 198, 2, p. 574-581 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Purification of lysosomes from guinea pig gastric mucosal cells by uptake of triton WR-1339

Madson, T. H., LaRusso, N. F. & Dozois, R. R., Jan 1 1981, In : Gastroenterology. 80, 5 II, 1 p.

Research output: Contribution to journalArticle

Purinergic regulation of acid/base transport in human and rat biliary epithelial cell lines

Zsembery, Á., Spirl, C., Granato, A., Larusso, N. E., Okolicsanyi, L., Crepaldi, G. & Strazzabosco, M., Oct 13 1998, In : Hepatology. 28, 4 I, p. 914-920 7 p.

Research output: Contribution to journalArticle

43 Scopus citations

Quantitative assessment of the rat intrahepatic biliary system by three-dimensional reconstruction

Masyuk, T. V., Ritman, E. L. & LaRusso, N. F., Jan 1 2001, In : American Journal of Pathology. 158, 6, p. 2079-2088 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

Quantitative importance of biliary excretion to the turnover of hepatic lysosomal enzymes

Nakano, A., Marks, D. L., Tietz, P. S., De Groen, P. C. & Larusso, N. F., Jul 1995, In : Hepatology. 22, 1, p. 262-266 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Rab3D, a small GTP-binding protein implicated in regulated secretion, is associated with the transcytotic pathway in rat hepatocytes

Larkin, J. M., Woo, B., Balan, V., Marks, D. L., Oswald, B. J., LaRusso, N. F. & McNiven, M. A., Jan 1 2000, In : Hepatology. 32, 2, p. 348-356 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Randomized clinical trial of long-acting somatostatin for autosomal dominant polycystic kidney and liver disease

Hogan, M. C., Masyuk, T. V., Page, L. J., Kubly, V. J., Bergstralh, E. J., Li, X., Kim, B., King, B. F., Glockner, J., Holmes, D. R., Rossetti, S., Harris, P. C., LaRusso, N. F. & Torres, V. E., Jun 1 2010, In : Journal of the American Society of Nephrology. 21, 6, p. 1052-1061 10 p.

Research output: Contribution to journalArticle

221 Scopus citations

Rapid Dissolution of Gallstones by Methyl Tert-Butyl Ether: Preliminary Observations

Allen, M. J., Borody, T. J., Bugliosi, T. F., May, G. R., Larusso, N. F. & Thistle, J. L., Jan 24 1985, In : New England Journal of Medicine. 312, 4, p. 217-220 4 p.

Research output: Contribution to journalArticle

195 Scopus citations

Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter

Lazaridis, K. N., Pham, L., Tietz, P., Marinelli, R. A., DeGroen, P. C., Levine, S., Dawson, P. A. & LaRusso, N. F., Dec 1 1997, In : Journal of Clinical Investigation. 100, 11, p. 2714-2721 8 p.

Research output: Contribution to journalArticle

Open Access
204 Scopus citations

Rat hepatocyte aquaporin-8 water channels are down-regulated in extrahepatic cholestasis

Carreras, F. I., Gradilone, S. A., Mazzone, A., García, F., Huang, B. Q., Ochoa, J. E., Tietz, P. S., LaRusso, N. F., Calamita, G. & Marinelli, R. A., May 1 2003, In : Hepatology. 37, 5, p. 1026-1033 8 p.

Research output: Contribution to journalArticle

57 Scopus citations

Rat hepatocytes transport water mainly via a non-channel-mediated pathway

Yano, M., Marinelli, R. A., Roberts, S. K., Balan, V., Pham, L., Tarara, J. E., De Groen, P. C. & LaRusso, N. F., Mar 22 1996, In : Journal of Biological Chemistry. 271, 12, p. 6702-6707 6 p.

Research output: Contribution to journalArticle

47 Scopus citations

Recent advances in the isolation of liver cells

Alpini, G., Phillips, J. O., Vroman, B. & Larusso, N. F., Aug 1994, In : Hepatology. 20, 2, p. 494-514 21 p.

Research output: Contribution to journalArticle

143 Scopus citations

Recurrence of primary sclerosing cholangitis following liver transplantation

Graziadei, I. W., Wiesner, R. H., Batts, K. P., Marotta, P. J., Larusso, N. F., Porayko, M. K., Eileen Hay, J., Gores, G. J., Charlton, M. R., Ludwig, J., Poterucha, J. J., Steers, J. L. & Krom, R. A. F., Jan 1 1999, In : Hepatology. 29, 4, p. 1050-1056 7 p.

Research output: Contribution to journalArticle

268 Scopus citations
Open Access
65 Scopus citations

Regulation of biliary secretion through apical purinergic receptors in cultured rat cholangiocytes

Schlenker, T., Romac, J. M. J., Sharara, A. I., Roman, R. M., Kim, S. J., Larusso, N., Liddle, R. A. & Gregory Fitz, J., Dec 9 1997, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 273, 5 36-5, p. G1108-G1117

Research output: Contribution to journalArticle

70 Scopus citations

Regulation of Ca2+ signaling in rat bile duct epithelia by inositol 1,4,5-trisphosphate receptor isoforms

Hirata, K., Dufour, J. F., Shibao, K., Knickelbein, R., O'Neill, A. F., Bode, H. P., Cassio, D., St-Pierre, M. V., LaRusso, N. F., Leite, M. F. & Nathanson, M. H., Jan 1 2002, In : Hepatology. 36, 2, p. 284-296 13 p.

Research output: Contribution to journalArticle

59 Scopus citations

Release of Luminal Exosomes Contributes to TLR4-Mediated Epithelial Antimicrobial Defense

Hu, G., Gong, A. Y., Roth, A. L., Huang, B. Q., Ward, H. D., Zhu, G., LaRusso, N. F., Hanson, N. D. & Chen, X. M., Apr 1 2013, In : PLoS pathogens. 9, 4, e1003261.

Research output: Contribution to journalArticle

83 Scopus citations

Role for Krüppel-Like Transcription Factor 11 in Mesenchymal Cell Function and Fibrosis

Mathison, A., Grzenda, A., Lomberk, G., Velez, G., Buttar, N., Tietz, P., Hendrickson, H., Liebl, A., Xiong, Y. Y., Gores, G., Fernandez-Zapico, M., LaRusso, N. F., Faubion, W., Shah, V. H. & Urrutia, R., Sep 16 2013, In : PloS one. 8, 9, e75311.

Research output: Contribution to journalArticle

17 Scopus citations

Role of the Intestinal Microbiome in Cholestatic Liver Disease

La Russo, N. F., Tabibian, J. H. & O'Hara, S. P., Mar 1 2017, In : Digestive Diseases. 35, 3, p. 166-168 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Sampling intestinal content with a sequestering capsule. A noninvasive technique for determining bile acid kinetics in man

Hoffman, N. E., Larusso, N. F. & Hofmann, A. F., Dec 1 1976, In : Mayo Clinic proceedings. 51, 3, p. 171-175 5 p.

Research output: Contribution to journalArticle

Sclerosing cholangitis

Marotta, P. J., LaRusso, N. F. & Wiesner, R. H., Dec 1997, In : Bailliere's Clinical Gastroenterology. 11, 4, p. 781-800 20 p.

Research output: Contribution to journalArticle

9 Scopus citations

Secretin induces the apical insertion of aquaporin-1 water channels in rat cholangiocytes

Marinelli, R. A., Tietz, P. S., Pham, L. D., Rueckert, L., Agre, P. & LaRusso, N. F., Jan 1 1999, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 276, 1 39-1, p. G280-G286

Research output: Contribution to journalArticle

131 Scopus citations
160 Scopus citations

Secretin stimulates exocytosis in isolated bile duct epithelial cells by a cyclic AMP-mediated mechanism

Kato, A., Gores, G. J. & LaRusso, N. F., Jan 1 1992, In : Journal of Biological Chemistry. 267, 22, p. 15523-15529 7 p.

Research output: Contribution to journalArticle

126 Scopus citations

Selection and timing of liver transplantation in primary biliary cirrhosis and primary sclerosing cholangitis

Wiesner, R. H., Porayko, M. K., Dickson, E. R., Gores, G. J., Larusso, N. F., Hay, J. E., Wahlstrom, H. E. & Krom, R. A. F., Nov 1992, In : Hepatology. 16, 5, p. 1290-1299 10 p.

Research output: Contribution to journalArticle

134 Scopus citations

Serum lipid and fat-soluble vitamin levels in primary sclerosing cholangitis

Jorgensen, R. A., Lindor, K. D., Sartin, J. S., LaRusso, N. F. & Wiesner, R. H., Apr 1995, In : Journal of clinical gastroenterology. 20, 3, p. 215-219 5 p.

Research output: Contribution to journalArticle

61 Scopus citations

Simple method for simultaneous specific activity measurements in a mixture of radiolabeled bile acids

Belobaba, D. T. E., Carlson, G. L. & LaRusso, N. F., Apr 21 1979, In : Journal of Chromatography A. 172, 1, p. 410-416 7 p.

Research output: Contribution to journalArticle

2 Scopus citations