• 26904 Citations
  • 93 Scopus h-Index
1973 …2019
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Research Output 1973 2019

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Article
2000
2 Citations (Scopus)

Biliary tract physiology

Prall, R. T. & La Russo, N. F., 2000, In : Current Opinion in Gastroenterology. 16, 5, p. 432-436 5 p.

Research output: Contribution to journalArticle

Biliary Tract
Bile
Bile Ducts
Bile Acids and Salts
Nervous System
8 Citations (Scopus)

Current therapies and clinical controversies in the management of primary sclerosing cholangitis.

Prall, R. T., Lindor, K. D., Wiesner, R. H. & La Russo, N. F., Apr 2000, In : Current Gastroenterology Reports. 2, 2, p. 99-103 5 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Liver Transplantation
Intrahepatic Bile Ducts
Extrahepatic Bile Ducts
Cholangiocarcinoma
1 Citation (Scopus)

Defining the relationship between antoimmune disease and primary sclerosing cholangitis

Talwalkar, J. A., La Russo, N. F. & Lindor, K. D., 2000, In : American Journal of Gastroenterology. 95, 11, p. 3024-3026 3 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
HLA Antigens
Inflammatory Bowel Diseases
Cellular Immunity
Autoimmune Diseases
49 Citations (Scopus)

Expression of aquaporin-4 water channels in rat cholangiocytes

Marinelli, R. A., Pham, L. D., Tietz, P. S. & La Russo, N. F., 2000, In : Hepatology. 31, 6, p. 1313-1317 5 p.

Research output: Contribution to journalArticle

Aquaporin 4
Aquaporins
Secretin
Membranes
Bile
492 Citations (Scopus)

Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism

Jaiswal, M., La Russo, N. F., Burgart, L. J. & Gores, G. J., Jan 1 2000, In : Cancer Research. 60, 1, p. 184-190 7 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
DNA Repair
DNA Damage
Nitric Oxide
Cytokines
132 Citations (Scopus)

Magnetic resonance cholangiography in patients with biliary disease: Its role in primary sclerosing cholangitis

Angulo, P., Pearce, D. H., Johnson, C. D., Henry, J. J., La Russo, N. F., Petersen, B. T. & Lindor, K. D., 2000, In : Journal of Hepatology. 33, 4, p. 520-527 8 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangiography
Magnetic Resonance Spectroscopy
Endoscopic Retrograde Cholangiopancreatography
Factor IX
26 Citations (Scopus)

Modified culture conditions enhance expression of differentiated phenotypic properties of normal rat cholangiocytes

Salter, K. D., Roman, R. M., La Russo, N. F., Fitz, J. G. & Doctor, R. B., 2000, In : Laboratory Investigation. 80, 11, p. 1775-1778 4 p.

Research output: Contribution to journalArticle

Bile Ducts
Culture Media
Cell Differentiation
Phenotype
Cell Line
114 Citations (Scopus)

Oral budesonide in the treatment of primary sclerosing cholangitis

Angulo, P., Batts, K. P., Jorgensen, R. A., La Russo, N. F. & Lindor, K. D., 2000, In : American Journal of Gastroenterology. 95, 9, p. 2333-2337 5 p.

Research output: Contribution to journalArticle

Budesonide
Sclerosing Cholangitis
Therapeutics
Femur Neck
Gastroenterology
40 Citations (Scopus)

Perfused rat intrahepatic bile ducts secrete and absorb water, solute, and ions

Masyuk, A. I., Gong, A. Y., Kip, S., Burke, M. J. & La Russo, N. F., 2000, In : Gastroenterology. 119, 6, p. 1672-1680 9 p.

Research output: Contribution to journalArticle

Intrahepatic Bile Ducts
Ions
Taurocholic Acid
Water
Bile Acids and Salts
12 Citations (Scopus)
Microsatellite Instability
Tumor Suppressor Genes
Carcinogenesis
22 Citations (Scopus)

Rab3D, a small GTP-binding protein implicated in regulated secretion, is associated with the transcytotic pathway in rat hepatocytes

Larkin, J. M., Woo, B., Balan, V., Marks, D. L., Oswald, B. J., La Russo, N. F. & Mc Niven, M. A., 2000, In : Hepatology. 32, 2, p. 348-356 9 p.

Research output: Contribution to journalArticle

Transcytosis
Guanosine Triphosphate
Hepatocytes
Carrier Proteins
Cytoplasm
287 Citations (Scopus)
Sclerosing Cholangitis
Cholangiocarcinoma
Serum
Tumor Biomarkers
Bile Ducts
1999
5 Citations (Scopus)

Biliary tract physiology

Prall, R. T. & La Russo, N. F., 1999, In : Current Opinion in Gastroenterology. 15, 5, p. 423-429 7 p.

Research output: Contribution to journalArticle

Biliary Tract
Bile
Bile Ducts
Bile Acids and Salts
Electrolytes
65 Citations (Scopus)

Cholangiocarcinomas express Fas ligand and disable the Fas receptor

Que, F., Phan, V. A., Phan, V. H., Celli, A., Batts, K., La Russo, N. F. & Gores, G. J., 1999, In : Hepatology. 30, 6, p. 1398-1404 7 p.

Research output: Contribution to journalArticle

CD95 Antigens
Fas Ligand Protein
Cholangiocarcinoma
Apoptosis
Cell Death
83 Citations (Scopus)
Cryptosporidium parvum
Fas Ligand Protein
Epithelium
Apoptosis
Neutralizing Antibodies
23 Citations (Scopus)

GUDC inhibits cytochrome c release from human cholangiocyte mitochondria

Que, F., Phan, V. A., Phan, V. H., La Russo, N. F. & Gores, G. J., May 15 1999, In : Journal of Surgical Research. 83, 2, p. 100-105 6 p.

Research output: Contribution to journalArticle

Cytochromes c
Mitochondria
Apoptosis
Ursodeoxycholic Acid
Caspase 3
6 Citations (Scopus)

Human intestinal and biliary cryptosporidiosis

Chen, X. M. & La Russo, N. F., Oct 1999, In : World Journal of Gastroenterology. 5, 5, p. 424-429 6 p.

Research output: Contribution to journalArticle

Cryptosporidium parvum
Cryptosporidiosis
266 Citations (Scopus)

Long-term results of patients undergoing liver transplantation for primary sclerosing cholangitis

Graziadei, I. W., Wiesner, R. H., Marotta, P. J., Porayko, M. K., Eileen Hay, J., Charlton, M. R., Poterucha, J. J., Rosen, C. B., Gores, G. J., La Russo, N. F. & Krom, R. A. F., 1999, In : Hepatology. 30, 5, p. 1121-1127 7 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Liver Transplantation
Graft Survival
Pathologic Constriction
Recurrence
779 Citations (Scopus)

Medical progress: Biliary tract cancers

De Groen, P. C., Gores, G. J., La Russo, N. F., Gunderson, L. L. & Nagorney, D. M., Oct 28 1999, In : New England Journal of Medicine. 341, 18, p. 1368-1378 11 p.

Research output: Contribution to journalArticle

Biliary Tract Neoplasms
X Ray Computed Tomography
Cholangiography
Biliary Tract
59 Citations (Scopus)

Oral nicotine in treatment of primary sclerosing cholangitis. A pilot study

Angulo, P., Bharucha, A. E., Jorgensen, R. A., DeSotel, C. K., Sandborn, W. J., La Russo, N. F. & Lindor, K. D., 1999, In : Digestive Diseases and Sciences. 44, 3, p. 602-607 6 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Nicotine
Cotinine
Therapeutics
Biochemistry
264 Citations (Scopus)

Recurrence of primary sclerosing cholangitis following liver transplantation

Graziadei, I. W., Wiesner, R. H., Batts, K. P., Marotta, P. J., La Russo, N. F., Porayko, M. K., Eileen Hay, J., Gores, G. J., Charlton, M. R., Ludwig, J., Poterucha, J. J., Steers, J. L. & Krom, R. A. F., 1999, In : Hepatology. 29, 4, p. 1050-1056 7 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Liver Transplantation
Recurrence
Pathologic Constriction
Liver
129 Citations (Scopus)

Secretin induces the apical insertion of aquaporin-1 water channels in rat cholangiocytes

Marinelli, R. A., Tietz, P. S., Pham, L. D., Rueckert, L., Agre, P. & La Russo, N. F., Jan 1999, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 276, 1 39-1

Research output: Contribution to journalArticle

Aquaporin 1
Aquaporins
Secretin
Bile
Cell Membrane
9 Citations (Scopus)
Sclerosing Cholangitis
Pathology
Cholagogues and Choleretics
Cholestasis
Immunosuppressive Agents
103 Citations (Scopus)

The relative role of the Child-Pugh classification and the Mayo natural history model in the assessment of survival in patients with primary sclerosing cholangitis

Kim, W. R., Poterucha, J. J., Wiesner, R. H., La Russo, N. F., Lindor, K. D., Petz, J., Therneau, T. M., Malinchoc, M. & Dickson, E. R., 1999, In : Hepatology. 29, 6, p. 1643-1648 6 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Natural History
Survival
Confidence Intervals
Liver Cirrhosis
51 Citations (Scopus)

Time course of histological progression in primary sclerosing cholangitis

Angulo, P., Larson, D. R., Therneau, T. M., La Russo, N. F., Batts, K. P. & Lindor, K. D., Nov 1999, In : American Journal of Gastroenterology. 94, 11, p. 3310-3313 4 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Biopsy
Liver
Observation
Clinical Trials
1998
58 Citations (Scopus)

Anatomy of the human biliary system studied by quantitative computer- aided three-dimensional imaging techniques

Ludwig, J., Ritman, E. L., La Russo, N. F., Sheedy, P. F. & Zumpe, G., 1998, In : Hepatology. 27, 4, p. 893-899 7 p.

Research output: Contribution to journalArticle

Three-Dimensional Imaging
Biliary Tract
Anatomy
Microvilli
Liver
13 Citations (Scopus)
Intrahepatic Bile Ducts
Ducts
Rats
Epithelial Cells
Cells
11 Citations (Scopus)

Cholangiocyte-specific rat liver proteins identified by establishment of a two-dimensional gel protein database

Tietz, P., De Groen, P. C., Anderson, N. L., Sims, C., Esquer-Blasco, R., Meheus, L., Raymackers, J., Dauwe, M. & La Russo, N. F., 1998, In : Electrophoresis. 19, 18, p. 3207-3212 6 p.

Research output: Contribution to journalArticle

Protein Databases
Liver
Rats
Gels
Proteins
68 Citations (Scopus)

Cryptosporidium parvum is cytopathic for cultured human biliary epithelia via an apoptotic mechanism

Chen, X. M., Levine, S. A., Tietz, P., Krueger, E., Mc Niven, M. A., Jefferson, D. M., Mahle, M. & La Russo, N. F., 1998, In : Hepatology. 28, 4 I, p. 906-913 8 p.

Research output: Contribution to journalArticle

Cryptosporidium parvum
Epithelium
Cryptosporidiosis
Sporozoites
Sclerosing Cholangitis
30 Citations (Scopus)

Different susceptibility of mice to immune-mediated cholangitis induced by immunization with carbonic anhydrase II

Ueno, Y., Ishii, M., Takahashi, S., Igarashi, T., Toyota, T. & La Russo, N. F., May 1998, In : Laboratory Investigation. 78, 5, p. 629-637 9 p.

Research output: Contribution to journalArticle

Carbonic Anhydrase II
Cholangitis
Immunization
Inbred DBA Mouse
Bovine Serum Albumin
39 Citations (Scopus)

Functional polarity of Na+/H+ and Cl-/HCO3/- exchangers in a rat cholangiocyte cell line

Spirlì, C., Granato, A., Zsembery, À., Anglani, F., Okolicsànyi, L., La Russo, N. F., Crepaldi, G. & Strazzabosco, M., 1998, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 275, 6 38-6

Research output: Contribution to journalArticle

Chloride-Bicarbonate Antiporters
Amiloride
Protein Isoforms
Cell Line
Membranes
117 Citations (Scopus)
Buthionine Sulfoximine
Glutathione
Apoptosis
Oxidative Stress
Proteins
145 Citations (Scopus)

Heterogeneity of the proliferative capacity of rat cholangiocytes after bile duct ligation

Alpini, G., Glaser, S. S., Ueno, Y., Pham, L., Podila, P. V., Caligiuri, A., LeSage, G. & La Russo, N. F., Apr 1998, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 274, 4 37-4

Research output: Contribution to journalArticle

Intrahepatic Bile Ducts
Secretin
Bile Ducts
Ligation
Epithelial Cells
43 Citations (Scopus)

Purinergic regulation of acid/base transport in human and rat biliary epithelial cell lines

Zsembery, Á., Spirl, C., Granato, A., La Russo, N. F., Okolicsanyi, L., Crepaldi, G. & Strazzabosco, M., 1998, In : Hepatology. 28, 4 I, p. 914-920 7 p.

Research output: Contribution to journalArticle

Adenosine Triphosphate
Epithelial Cells
Cell Line
Acids
Purinergic Agonists
1997
32 Citations (Scopus)

Aquaporin water channels in liver: Their significance in bile formation

Marinelli, R. A. & La Russo, N. F., Nov 1997, In : Hepatology. 26, 5, p. 1081-1084 4 p.

Research output: Contribution to journalArticle

Aquaporins
Bile
Liver
76 Citations (Scopus)

Are patients with cirrhotic stage primary sclerosing cholangitis at risk for the development of hepatocellular cancer?

Harnois, D., Gores, G. J., Ludwig, J., Steers, J. L., La Russo, N. F. & Wiesner, R. H., Sep 1997, In : Journal of Hepatology. 27, 3, p. 512-516 5 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Liver Neoplasms
Hepatocellular Carcinoma
Liver Transplantation
Cholangiocarcinoma
104 Citations (Scopus)

Bcl-2 is overexpressed and alters the threshold for apoptosis in a cholangiocarcinoma cell line

Harnois, D., Que, F., Celli, A., La Russo, N. F. & Gores, G. J., Oct 1997, In : Hepatology. 26, 4, p. 884-890 7 p.

Research output: Contribution to journalArticle

B-Cell Leukemia
Cholangiocarcinoma
B-Cell Lymphoma
Apoptosis
Cell Line
23 Citations (Scopus)

Characterization of apical and basolateral plasma membrane domains derived from cultured rat cholangiocytes

Tietz, P., Levine, S., Holman, R., Fretham, C. & La Russo, N. F., Dec 15 1997, In : Analytical Biochemistry. 254, 2, p. 192-199 8 p.

Research output: Contribution to journalArticle

Cell membranes
Rats
Cell Membrane
Isopycnic Centrifugation
Intrahepatic Bile Ducts
52 Citations (Scopus)
Rodentia
Apoptosis
Caspase 1
Peptide Hydrolases
In Vitro Techniques

Gene expression and polarized distribution of membrane acid/base carriers in a differentiated rat cholangiocyte cell line (NRC-1)

Spirli, C., Granato, A., Zsembery, A., Okolicsanyi, L., La Russo, N. F. & Strazzabosco, M., 1997, In : Italian Journal of Gastroenterology and Hepatology. 29, 1, p. 99 1 p.

Research output: Contribution to journalArticle

Gene Expression
Cell Line
Acids
Membranes
52 Citations (Scopus)

Interactions between chronic liver disease and inflammatory bowel disease

Loftus, Jr, E. V., Sandborn, W. J., Lindor, K. D. & La Russo, N. F., Dec 1997, In : Inflammatory Bowel Diseases. 3, 4, p. 288-302 15 p.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Liver Diseases
Chronic Disease
Inflammatory Bowel Disease 3
Inflammatory Bowel Disease 4
52 Citations (Scopus)
Sodium-Glucose Transport Proteins
Monosaccharides
Reverse Transcriptase Polymerase Chain Reaction
Glucose
Bile
116 Citations (Scopus)

Molecular and functional heterogeneity of cholangiocytes from rat liver after bile duct ligation

Alpini, G., Ulrich, C., Roberts, S., Phillips, J. O., Ueno, Y., Podila, P. V., Colegio, O., LeSage, G. D., Miller, L. J. & La Russo, N. F., Feb 1997, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 272, 2 35-2

Research output: Contribution to journalArticle

Bile Ducts
Ligation
Cystic Fibrosis Transmembrane Conductance Regulator
Liver
Biliary Tract
202 Citations (Scopus)

Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter

Lazaridis, K. N., Pham, L., Tietz, P., Marinelli, R. A., DeGroen, P. C., Levine, S., Dawson, P. A. & La Russo, N. F., Dec 1 1997, In : Journal of Clinical Investigation. 100, 11, p. 2714-2721 8 p.

Research output: Contribution to journalArticle

Bile Acids and Salts
Taurocholic Acid
Liver
Transcytosis
sodium-bile acid cotransporter
70 Citations (Scopus)

Regulation of biliary secretion through apical purinergic receptors in cultured rat cholangiocytes

Schlenker, T., Romac, J. M. J., Sharara, A. I., Roman, R. M., Kim, S. J., La Russo, N. F., Liddle, R. A. & Gregory Fitz, J., 1997, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 273, 5 36-5

Research output: Contribution to journalArticle

Purinergic Receptors
Adenosine Triphosphate
Bile
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
Bumetanide
9 Citations (Scopus)

Sclerosing cholangitis

Marotta, P. J., La Russo, N. F. & Wiesner, R. H., Dec 1997, In : Bailliere's Clinical Gastroenterology. 11, 4, p. 781-800 20 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Biliary Liver Cirrhosis
Cholestasis
Biliary Tract
Portal Hypertension
2 Citations (Scopus)

Search for medical treatment for primary biliary cirrhosis

La Russo, N. F., 1997, In : Lancet. 350, 9084, p. 1046 1 p.

Research output: Contribution to journalArticle

Cholagogues and Choleretics
Ursodeoxycholic Acid
Biliary Liver Cirrhosis
Immunosuppressive Agents
Methotrexate
158 Citations (Scopus)
Aquaporin 1
Aquaporins
Secretin
Cell membranes
Rats
107 Citations (Scopus)

The pathobiology of biliary epithelia

Roberts, S. K., Ludwig, J. & La Russo, N. F., 1997, In : Gastroenterology. 112, 1, p. 269-279 11 p.

Research output: Contribution to journalArticle

Theoretical Models
Epithelium
Cell Physiological Phenomena
Allergy and Immunology
Bile
1996
Ice
ice
apoptosis
Chemical activation
Apoptosis