• 26935 Citations
  • 93 Scopus h-Index
1973 …2019
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Research Output 1973 2019

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Article
80 Citations (Scopus)

Engineered measles virus as a novel oncolytic viral therapy system for hepatocellular carcinoma

Blechacz, B., Splinter, P. L., Greiner, S., Myers, R., Peng, K-W., Federspiel, M. J., Russell, S. J. & La Russo, N. F., Dec 2006, In : Hepatology. 44, 6, p. 1465-1477 13 p.

Research output: Contribution to journalArticle

Measles virus
Hepatocellular Carcinoma
Viruses
Carcinoembryonic Antigen
Cell Line
57 Citations (Scopus)

Enhanced autoreactivity of T-lymphocytes in primary sclerosing cholangitis

Lindor, K. D., Wiesner, R. H., La Russo, N. F. & Homburger, H. A., 1987, In : Hepatology. 7, 5, p. 884-888 5 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
T-Lymphocytes
Mixed Lymphocyte Culture Test
Cytotoxic T-Lymphocytes
Lymphocyte Activation
28 Citations (Scopus)
Bile Acids and Salts
Feces
Healthy Volunteers
Diet
Gas Chromatography
18 Citations (Scopus)

Epidermal growth factor protects the apical junctional complexes from hydrogen peroxide in bile duct epithelium

Guntaka, S. R., Samak, G., Seth, A., La Russo, N. F. & Rao, R., Sep 2011, In : Laboratory Investigation. 91, 9, p. 1396-1409 14 p.

Research output: Contribution to journalArticle

Tight Junctions
Bile Ducts
Epidermal Growth Factor
Hydrogen Peroxide
Epithelium
9 Citations (Scopus)

Epigenetics in the Primary Biliary Cholangitis and Primary Sclerosing Cholangitis

Cheung, A. C., La Russo, N. F., Gores, G. J. & Lazaridis, K. N., May 1 2017, In : Seminars in Liver Disease. 37, 2, p. 159-174 16 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangitis
Epigenomics
Genes
Genome-Wide Association Study
1 Citation (Scopus)

Erratum: Human Oggl, a protein involved in the repair of 8-oxoguanine, is inhibited by nitric oxide (Cancer Research (September 1, 2001) (6388-6393))

Jaiswal, M., La Russo, N. F., Nishioka, K., Nakabeppu, Y. & Gores, G. J., Oct 15 2001, In : Cancer Research. 61, 20, p. 7705 1 p.

Research output: Contribution to journalArticle

Nitric Oxide
Research
Neoplasms
Proteins
8-hydroxyguanine

Ethynylestradiol inhibits bile flow and biliary protein secretion but stimulates release of lysosomal enzymes into bile

Lopez del Pino, V., Carter, J. & La Russo, N. F., 1979, In : Gastroenterology. 76, 5 II, p. 1118 1 p.

Research output: Contribution to journalArticle

Bile
Enzymes
Proteins
8 Citations (Scopus)

ETS proto-oncogene 1 transcriptionally up-regulates the cholangiocyte senescence-associated protein cyclin-dependent kinase inhibitor 2A

O'Hara, S. P., Splinter, P. L., Trussoni, C. E., Lorenzo Pisarello, M. J., Loarca, L., Splinter, N. S., Schutte, B. F. & La Russo, N. F., Mar 24 2017, In : Journal of Biological Chemistry. 292, 12, p. 4833-4846 14 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase Inhibitor p16
Sclerosing Cholangitis
Proto-Oncogenes
Up-Regulation
Luciferases

Evidence suggesting lysosomes may modulate effects of estrogens on the liver

Lopez Del Pino, V., Kost, L. & La Russo, N. F., 1980, In : Gastroenterology. 78, 5 II, p. 1312 1 p.

Research output: Contribution to journalArticle

Lysosomes
Estrogens
Liver
2 Citations (Scopus)

Examining the increased IgM production and ursodeoxycholic acid treatment in PBC

Lazaridis, K. N. & La Russo, N. F., Feb 2005, In : Gastroenterology. 128, 2, p. 498-500 3 p.

Research output: Contribution to journalArticle

Cholagogues and Choleretics
Immunologic Memory
Ursodeoxycholic Acid
Biliary Liver Cirrhosis
Immunoglobulin M
105 Citations (Scopus)

Exosomes in the pathogenesis, diagnostics and therapeutics of liver diseases

Masyuk, A. I., Masyuk, T. V. & La Russo, N. F., Sep 2013, In : Journal of Hepatology. 59, 3, p. 621-625 5 p.

Research output: Contribution to journalArticle

Exosomes
Liver Diseases
Liver
Therapeutics
Multivesicular Bodies
9 Citations (Scopus)

Experimental models to study cholangiocyte biology

Tietz, P. S., Chen, X. M., Gong, A. Y., Huebert, R. C., Masyuk, A., Masyuk, T., Splinter, P. L. & La Russo, N. F., 2002, In : World Journal of Gastroenterology. 8, 1, p. 1-4 4 p.

Research output: Contribution to journalArticle

Bile Ducts
Theoretical Models
Cryptosporidium parvum
Biliary Tract
Bile
119 Citations (Scopus)

Expression and localization of aquaporin water channels in rat hepatocytes. Evidence for a role in canalicular bile secretion

Huebert, R. C., Splinter, P. L., Garcia, F., Marinelli, R. A. & La Russo, N. F., Jun 21 2002, In : Journal of Biological Chemistry. 277, 25, p. 22710-22717 8 p.

Research output: Contribution to journalArticle

Aquaporins
Bile
Rats
Hepatocytes
Cell membranes
27 Citations (Scopus)

Expression and subcellular localization of aquaporin water channels in the polarized hepatocyte cell line, WIF-B

Gradilone, S. A., Tietz, P. S., Splinter, P. L., Marinelli, R. A. & La Russo, N. F., Aug 18 2005, In : BMC Physiology. 5

Research output: Contribution to journalArticle

Aquaporins
Hepatocytes
Cell Line
Bile
B-Lymphocytes
49 Citations (Scopus)

Expression of aquaporin-4 water channels in rat cholangiocytes

Marinelli, R. A., Pham, L. D., Tietz, P. S. & La Russo, N. F., 2000, In : Hepatology. 31, 6, p. 1313-1317 5 p.

Research output: Contribution to journalArticle

Aquaporin 4
Aquaporins
Secretin
Membranes
Bile
110 Citations (Scopus)

Familial occurrence of primary sclerosing cholangitis and ulcerative colitis

Quigley, E. M. M., La Russo, N. F., Ludwig, J., MacSween, R. N., Birnie, G. G. & Watkinson, G., 1983, In : Gastroenterology. 85, 5, p. 1160-1165 6 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Ulcerative Colitis
Siblings

Farther, faster, and (hopefully) better!

Link, A. M. & La Russo, N. F., 1992, In : Gastroenterology. 103, 3, p. 1099-1101 3 p.

Research output: Contribution to journalArticle

Peer Review
9 Citations (Scopus)

Fibrolamellar hepatocellular carcinoma presenting with budd-chiari syndrome, right atrial thrombus, and pulmonary emboli

Asrani, S. K. & La Russo, N. F., Mar 2012, In : Hepatology. 55, 3, p. 977-978 2 p.

Research output: Contribution to journalArticle

Budd-Chiari Syndrome
X Ray Computed Tomography
Liver Neoplasms
Embolism
Heart Atria
19 Citations (Scopus)

Fluid-phase endocytosis by intrahepatic bile duct epithelial cells isolated from normal rat liver

Ishii, M., Vroman, B. & La Russo, N. F., 1990, In : Journal of Histochemistry and Cytochemistry. 38, 4, p. 515-524 10 p.

Research output: Contribution to journalArticle

Intrahepatic Bile Ducts
Endocytosis
Epithelial Cells
Liver
Acid Phosphatase
11 Citations (Scopus)
Bile Duct Diseases
Caroli Disease
Intrahepatic Bile Ducts
Extrahepatic Bile Ducts
Cholangiocarcinoma
3 Citations (Scopus)
Biological Transport
Cell Polarity
Cell membranes
Bile Ducts
Actins

Foreword

La Russo, N. F., 1991, In : Seminars in Liver Disease. 11, 1

Research output: Contribution to journalArticle

39 Citations (Scopus)

Functional polarity of Na+/H+ and Cl-/HCO3/- exchangers in a rat cholangiocyte cell line

Spirlì, C., Granato, A., Zsembery, À., Anglani, F., Okolicsànyi, L., La Russo, N. F., Crepaldi, G. & Strazzabosco, M., 1998, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 275, 6 38-6

Research output: Contribution to journalArticle

Chloride-Bicarbonate Antiporters
Amiloride
Protein Isoforms
Cell Line
Membranes

Fusion innovation

La Russo, N. F., Spurrier, B. & Farrugia, G., Jan 1 2015, In : T and D. 69, 1

Research output: Contribution to journalArticle

Fusion
Innovation
2 Citations (Scopus)

Gaining acceptance to gastroenterology: How the review process works

La Russo, N. F. & Link, A. M., 1993, In : Gastroenterology. 104, 5, p. 1252-1254 3 p.

Research output: Contribution to journalArticle

Gastroenterology
70 Citations (Scopus)

Gallbladder disease in patients with primary sclerosing cholangitis

Brandt, D. J., MacCarty, R. L., Charboneau, J. W., La Russo, N. F., Wiesner, R. H. & Ludwig, J., 1988, In : American Journal of Roentgenology. 150, 3, p. 571-574 4 p.

Research output: Contribution to journalArticle

Gallbladder Diseases
Sclerosing Cholangitis
Gallbladder
End Stage Liver Disease
Gallstones
7 Citations (Scopus)

Gastroenterology: An international journal

La Russo, N. F. & Link, A. M., 1995, In : Gastroenterology. 108, 3, p. 625-626 2 p.

Research output: Contribution to journalArticle

Gastroenterology
2 Citations (Scopus)

Gastroenterology's editors-in-chief: historical and personal perspectives of their editorships.

Fordtran, J. S., Goyal, R. K., Feldman, M., Soll, A. H., Trier, J. S., Ockner, R. K., La Russo, N. F., Podolsky, D. K., Brenner, D. A., Rustgi, A. K. & Omary, M. B., Jul 2013, In : Gastroenterology. 145, 1, p. 16-31 16 p.

Research output: Contribution to journalArticle

Gastroenterology
Personality

Gene expression and polarized distribution of membrane acid/base carriers in a differentiated rat cholangiocyte cell line (NRC-1)

Spirli, C., Granato, A., Zsembery, A., Okolicsanyi, L., La Russo, N. F. & Strazzabosco, M., 1997, In : Italian Journal of Gastroenterology and Hepatology. 29, 1, p. 99 1 p.

Research output: Contribution to journalArticle

Gene Expression
Cell Line
Acids
Membranes
70 Citations (Scopus)

Glucagon induces the plasma membrane insertion of functional aquaporin-8 water channels in isolated rat hepatocytes

Gradilone, S. A., García, F., Huebert, R. C., Tietz, P. S., Larocca, M. C., Kierbel, A., Carreras, F. I., La Russo, N. F. & Marinelli, R. A., Jun 1 2003, In : Hepatology. 37, 6, p. 1435-1441 7 p.

Research output: Contribution to journalArticle

Aquaporins
Glucagon
Hepatocytes
Cell Membrane
Permeability
117 Citations (Scopus)
Buthionine Sulfoximine
Glutathione
Apoptosis
Oxidative Stress
Proteins
23 Citations (Scopus)

GUDC inhibits cytochrome c release from human cholangiocyte mitochondria

Que, F., Phan, V. A., Phan, V. H., La Russo, N. F. & Gores, G. J., May 15 1999, In : Journal of Surgical Research. 83, 2, p. 100-105 6 p.

Research output: Contribution to journalArticle

Cytochromes c
Mitochondria
Apoptosis
Ursodeoxycholic Acid
Caspase 3

Hail to the chief-Keith Lindor, our new AASLD president

Shah, V., Gores, G. J. & La Russo, N. F., Feb 1 2016, In : Hepatology. 63, 2, p. 357-359 3 p.

Research output: Contribution to journalArticle

21st Century History
20th Century History
Medical Societies
Gastroenterology
79 Citations (Scopus)

HDAC6 inhibition restores ciliary expression and decreases tumor growth

Gradilone, S. A., Radtke, B. N., Bogert, P. S., Huang, B. Q., Gajdos, G. B. & La Russo, N. F., Apr 1 2013, In : Cancer Research. 73, 7, p. 2259-2270 12 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Cilia
Cholangiocarcinoma
Growth
Neoplasms
20 Citations (Scopus)

HDAC6 is overexpressed in cystic cholangiocytes and its inhibition reduces cystogenesis

Gradilone, S. A., Habringer, S., Masyuk, T. V., Howard, B. N., Masyuk, A. I. & La Russo, N. F., Mar 2014, In : American Journal of Pathology. 184, 3, p. 600-608 9 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Cysts
Cell Cycle
Liver
Pharmacology
2 Citations (Scopus)

Health reform: A community experience using design research as a guide

Severson, M. A., Wood, D. L., Chastain, C. N., Lee, L. G., Rees, A. C., Agerter, D. C., Holtz, C., Broers, J. K., Savoleinen, K. H., Spurrier, B. R. & La Russo, N. F., 2011, In : Mayo Clinic Proceedings. 86, 10, p. 973-980 8 p.

Research output: Contribution to journalArticle

Research Design
Health
Delivery of Health Care
Costs and Cost Analysis
Patient-Centered Care
42 Citations (Scopus)

Hepatic artery and portal vein remodeling in rat liver: Vascular response to selective cholangiocyte proliferation

Masyuk, T. V., Ritman, E. L. & La Russo, N. F., Apr 1 2003, In : American Journal of Pathology. 162, 4, p. 1175-1182 8 p.

Research output: Contribution to journalArticle

Hepatic Veins
Hepatic Artery
Portal Vein
Blood Vessels
Liver
51 Citations (Scopus)

Hepatic cystogenesis is associated with abnormal expression and location of ion transporters and water channels in an animal model of autosomal recessive polycystic kidney disease

Banales, J. M., Masyuk, T. V., Bogert, P. S., Huang, B. Q., Gradilone, S. A., Lee, S. O., Stroope, A. J., Masyuk, A. I., Medina, J. F. & La Russo, N. F., Dec 2008, In : American Journal of Pathology. 173, 6, p. 1637-1646 10 p.

Research output: Contribution to journalArticle

Autosomal Recessive Polycystic Kidney
Polycystic Kidney Diseases
Aquaporins
Ion Channels
Cysts
12 Citations (Scopus)

Hepatic extraction of renin: Quantitation and characterization in the isolated perfused rat liver

Keiser, J. A., Romero, J. C., Kost, L. J. & La Russo, N. F., 1987, In : Hepatology. 7, 6, p. 1254-1261 8 p.

Research output: Contribution to journalArticle

Renin
Liver
Enzyme Inhibitors
Liver Extracts
Taurocholic Acid
3 Citations (Scopus)

Hepatic metabolism and biliary excretion of metronidazole

La Russo, N. F., Lindmark, D. G. & Muller, M., 1976, In : Gastroenterology. 70, 5

Research output: Contribution to journalArticle

Metronidazole
Hepatobiliary Elimination
61 Citations (Scopus)
Cholecystokinin
Peptides
Liver
Tetragastrin
Sincalide
14 Citations (Scopus)

Hepatic processing of recombinant human renin: Mechanisms of uptake and degradation

Marks, D. L., Kost, L. J., Kuntz, S. M., Romero, J. C. & La Russo, N. F., 1991, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 261, 2 24-2

Research output: Contribution to journalArticle

Renin
Liver
Lysosomes
Bile
Hepatocytes
123 Citations (Scopus)

Hepatic processing of transforming growth factor β in the rat: Uptake, metabolism, and biliary excretion

Coffey, R. J., Kost, L. J., Lyons, R. M., Moses, H. L. & La Russo, N. F., 1987, In : Journal of Clinical Investigation. 80, 3, p. 750-757 8 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Transforming Growth Factor beta
Liver
Bile
Lysosomes
142 Citations (Scopus)

Hepatobiliary carcinoma associated with primary sclerosing cholangitis and chronic ulcerative colitis

Wee, A., Ludwig, J., Coffey, R. J., La Russo, N. F. & Wiesner, R. H., 1985, In : Human Pathology. 16, 7, p. 719-726 8 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Ulcerative Colitis
Carcinoma
Neoplasms
Bile Ducts
34 Citations (Scopus)

Hepatobiliary disease in inflammatory bowel disease

Balan, V. & La Russo, N. F., 1995, In : Gastroenterology Clinics of North America. 24, 3, p. 647-669 23 p.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Colonic Pouches
Cholangiocarcinoma
Colectomy
Biliary Tract
20 Citations (Scopus)

Hepato-renal pathology in Pkd2ws25/- mice, an animal model of autosomal dominant polycystic kidney disease

Stroope, A., Radtke, B., Huang, B., Masyuk, T., Torres, V., Ritman, E. & La Russo, N. F., Mar 2010, In : American Journal of Pathology. 176, 3, p. 1282-1291 10 p.

Research output: Contribution to journalArticle

Autosomal Dominant Polycystic Kidney
Animal Models
Pathology
Kidney
Liver
145 Citations (Scopus)

Heterogeneity of the proliferative capacity of rat cholangiocytes after bile duct ligation

Alpini, G., Glaser, S. S., Ueno, Y., Pham, L., Podila, P. V., Caligiuri, A., LeSage, G. & La Russo, N. F., Apr 1998, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 274, 4 37-4

Research output: Contribution to journalArticle

Intrahepatic Bile Ducts
Secretin
Bile Ducts
Ligation
Epithelial Cells
196 Citations (Scopus)

High-dose ursodeoxycholic acid as a therapy for patients with primary sclerosing cholangitis

Harnois, D., Angulo, P., Jorgensen, R. A., La Russo, N. F. & Lindor, K. D., May 2001, In : American Journal of Gastroenterology. 96, 5, p. 1558-1562 5 p.

Research output: Contribution to journalArticle

Ursodeoxycholic Acid
Sclerosing Cholangitis
Placebos
Survival
Therapeutics
20 Citations (Scopus)

HIV-1 tat protein suppresses cholangiocyte toll- like receptor 4 expression and defense against cryptosporidium parvum

O'Hara, S. P., Small, A. J., Gajdos, G. B., Badley, A. D., Chen, X. M. & La Russo, N. F., Apr 15 2009, In : Journal of Infectious Diseases. 199, 8, p. 1195-1204 10 p.

Research output: Contribution to journalArticle

tat Gene Products
Cryptosporidium parvum
Toll-Like Receptor 4
HIV-1
Cryptosporidiosis
1 Citation (Scopus)

Hormones and microtubular binding agents selectively alter biliary lysosomal protein excretion

Sewell, R. B., Kost, L. J., Carter, J. A. & La Russo, N. F., 1981, In : Gastroenterology. 80, 5 II, p. 1281 1 p.

Research output: Contribution to journalArticle

Hormones
lysosomal proteins