• 26846 Citations
  • 93 Scopus h-Index
1973 …2019
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Research Output 1973 2019

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69 Citations (Scopus)

{A figure is presented}The Utility of Lens Culinaris Agglutinin-Reactive α-Fetoprotein in the Diagnosis of Hepatocellular Carcinoma: Evaluation in a United States Referral Population

Leerapun, A., Suravarapu, S. V., Bida, J. P., Clark, R. J., Sanders, E. L., Mettler, T. A., Stadheim, L. M., Aderca, I., Moser, C. D., Nagorney, D. M., La Russo, N. F., de Groen, P. C., Menon, K. V. N., Lazaridis, K. N., Gores, G. J., Charlton, M. R., Roberts, R. O., Therneau, T. M., Katzmann, J. A. & Roberts, L. R., Mar 2007, In : Clinical Gastroenterology and Hepatology. 5, 3, p. 394-402 9 p.

Research output: Contribution to journalArticle

Fetal Proteins
Hepatocellular Carcinoma
Referral and Consultation
Population
lentil lectin
56 Citations (Scopus)

Abnormalities in tests of copper metabolism in primary sclerosing cholangitis

Gross, J. B., Ludwig, J., Wiesner, R. H., McCall, J. T. & La Russo, N. F., 1985, In : Gastroenterology. 89, 2, p. 272-278 7 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Copper
Liver
Fibrosis
Hepatolenticular Degeneration
53 Citations (Scopus)

Abnormalities of chemical tests for copper metabolism in chronic active liver disease: differentiation from Wilson's disease

La Russo, N. F., Summerskill, W. H. J. & McCall, J. T., 1976, In : Gastroenterology. 70, 5 I, p. 653-655 3 p.

Research output: Contribution to journalArticle

Hepatolenticular Degeneration
Ceruloplasmin
Pigmentation
Cornea
Liver Diseases
19 Citations (Scopus)

Absence of strand breaks in deoxyribonucleic acid treated with metronidazole

La Russo, N. F., Tomasz, M., Kaplan, D. & Mueller, M., 1978, In : Antimicrobial Agents and Chemotherapy. 13, 1, p. 19-24 6 p.

Research output: Contribution to journalArticle

Metronidazole
DNA
Viscosity
Dithionite
Bacteriophage T7
81 Citations (Scopus)

Absence of the intestinal microbiota exacerbates hepatobiliary disease in a murine model of primary sclerosing cholangitis in mice

Tabibian, J. H., O'Hara, S. P., Trussoni, C. E., Tietz, P. S., Splinter, P. L., Mounajjed, T., Hagey, L. R. & La Russo, N. F., 2015, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Ursodeoxycholic Acid
Microbiota
Biochemistry
Galactosidases
1 Citation (Scopus)

Academic internal medicine: challenges and opportunities - Part II

Costa, S. T., Brater, D. C., Coughlin, J. R., Danoff, D., Goode, L. D., Hazzard, W. R., La Russo, N. F., Matherlee, K. R., Spurrier, B. R. & Stolp-Smith, S. C., 2000, In : American Journal of Medicine. 108, 7, p. 601-608 8 p.

Research output: Contribution to journalArticle

Quality of Health Care
Internal Medicine
Medical Schools
Teaching Hospitals
Genetic Therapy
328 Citations (Scopus)

A cellular micro-RNA, let-7i, regulates toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection

Chen, X. M., Splinter, P. L., O'Hara, S. P. & La Russo, N. F., Sep 28 2007, In : Journal of Biological Chemistry. 282, 39, p. 28929-28938 10 p.

Research output: Contribution to journalArticle

Cryptosporidium parvum
Toll-Like Receptor 4
MicroRNAs
Toll-Like Receptors
Infection
57 Citations (Scopus)

Activation of Trpv4 Reduces the Hyperproliferative Phenotype of Cystic Cholangiocytes From an Animal Model of ARPKD

Gradilone, S. A., Masyuk, T. V., Huang, B. Q., Banales, J. M., Lehmann, G. L., Radtke, B. N., Stroope, A., Masyuk, A. I., Splinter, P. L. & La Russo, N. F., Jul 2010, In : Gastroenterology. 139, 1

Research output: Contribution to journalArticle

Autosomal Recessive Polycystic Kidney
TRPV Cation Channels
Polycystic Kidney Diseases
Animal Models
Phenotype
2 Citations (Scopus)

Acute administration of ursodeoxycholic acid decreases biliary cholesterol secretion in man

Sama, C., Lopez, V., La Russo, N. F. & Thistle, J. L., 1980, In : Gastroenterology. 79, 5 II, p. 1052 1 p.

Research output: Contribution to journalArticle

Ursodeoxycholic Acid
Cholesterol
45 Citations (Scopus)

Advances in primary sclerosing cholongitis

Lindor, K. D., Wiesner, R. H., MacCarty, R. L., Ludwig, J. & La Russo, N. F., 1990, In : The American journal of medicine. 89, 1, p. 73-80 8 p.

Research output: Contribution to journalArticle

Intrahepatic Bile Ducts
Extrahepatic Bile Ducts
Sclerosing Cholangitis
Poisons
Ulcerative Colitis
97 Citations (Scopus)

Agonist-induced coordinated trafficking of functionally related transport proteins for water and ions in cholangiocytes

Tietz, P. S., Marinelli, R. A., Chen, X. M., Huang, B., Cohn, J., Kole, J., Mc Niven, M. A., Alper, S. & La Russo, N. F., May 30 2003, In : Journal of Biological Chemistry. 278, 22, p. 20413-20419 7 p.

Research output: Contribution to journalArticle

Aquaporin 1
Carrier Proteins
Ions
Cystic Fibrosis
Water
2 Citations (Scopus)

A learner-centered academic career development curriculum.

McDonald, F. S., Schultz, H. J. & La Russo, N. F., May 2002, In : Academic medicine : journal of the Association of American Medical Colleges. 77, 5, p. 463 1 p.

Research output: Contribution to journalArticle

Staff Development
Medical Faculties
academic career
curriculum development
Internship and Residency
46 Citations (Scopus)

Alterations in hepatocyte lysosomes in experimental hepatic copper overload in rats

Myers, B. M., Prendergast, F. G., Holman, R., Kuntz, S. M. & La Russo, N. F., 1993, In : Gastroenterology. 105, 6, p. 1814-1823 10 p.

Research output: Contribution to journalArticle

Lysosomes
Copper
Hepatocytes
Liver
Membrane Fluidity
74 Citations (Scopus)

Alterations in the structure, physicochemical properties, and pH of hepatocyte lysosomes in experimental iron overload

Myers, B. M., Prendergast, F. G., Holman, R., Kuntz, S. M. & La Russo, N. F., 1991, In : Journal of Clinical Investigation. 88, 4, p. 1207-1215 9 p.

Research output: Contribution to journalArticle

Iron Overload
Lysosomes
Hepatocytes
Iron
Membrane Fluidity
96 Citations (Scopus)
Alternative Splicing
Bile Acids and Salts
Sodium
Ileum
Hepatocytes
66 Citations (Scopus)

A mouse model of autosomal recessive polycystic kidney disease with biliary duct and proximal tubule dilatation

Woollard, J. R., Punyashtiti, R., Richardson, S., Masyuk, T. V., Whelan, S., Huang, B. Q., Lager, D. J., Van Deursen, J., Torres, V., Gattone, V. H., La Russo, N. F., Harris, P. C. & Ward, C. J., Aug 2007, In : Kidney International. 72, 3, p. 328-336 9 p.

Research output: Contribution to journalArticle

Autosomal Recessive Polycystic Kidney
Dilatation
Kidney
Bile Ducts
Liver
5 Citations (Scopus)

An aluminum silicate binding assay for quantitationof degradation of cholecystokinin octapeptide and other short peptides

Janas, R. M., Marks, D. L. & La Russo, N. F., 1992, In : Analytical Biochemistry. 206, 1, p. 6-11 6 p.

Research output: Contribution to journalArticle

Aluminum Silicates
Sincalide
Assays
Degradation
Peptides
58 Citations (Scopus)

Anatomy of the human biliary system studied by quantitative computer- aided three-dimensional imaging techniques

Ludwig, J., Ritman, E. L., La Russo, N. F., Sheedy, P. F. & Zumpe, G., 1998, In : Hepatology. 27, 4, p. 893-899 7 p.

Research output: Contribution to journalArticle

Three-Dimensional Imaging
Biliary Tract
Anatomy
Microvilli
Liver
4 Citations (Scopus)

AN IMPROVED METHOD FOR FÆCAL COLLECTION: THE FÆCAL FIELD-KIT

Hoffman, N. E., La Russo, N. F. & Hofmann, A. F., Jun 23 1973, In : The Lancet. 301, 7817, p. 1422-1423 2 p.

Research output: Contribution to journalArticle

Specimen Handling
Feces

An Octogenarian with Acute Epigastric Pain: More Than Meets the Eye

Lynn, A., Tabibian, J. H. & La Russo, N. F., Feb 1 2016, In : Gastroenterology. 150, 2, p. e5-e6

Research output: Contribution to journalArticle

Choledocholithiasis
Incidental Findings
X Ray Computed Tomography
Acute Pain
Abdominal Pain
19 Citations (Scopus)

A novel incentive system for faculty in an academic medical center

Brandt, T. L., Romme, C. R., La Russo, N. F. & Lindor, K. D., Nov 5 2002, In : Annals of Internal Medicine. 137, 9, p. 738-743 6 p.

Research output: Contribution to journalArticle

Motivation
Physicians
Efficiency
Health Services Accessibility
Aptitude
54 Citations (Scopus)

Apical organelle discharge by Cryptosporidium parvum is temperature, cytoskeleton, and intracellular calcium dependent and required for host cell invasion

Chen, X. M., O'Hara, S. P., Huang, B. Q., Nelson, J. B., Lin, J. J. C., Zhu, G., Ward, H. D. & La Russo, N. F., Dec 2004, In : Infection and Immunity. 72, 12, p. 6806-6816 11 p.

Research output: Contribution to journalArticle

Cryptosporidium parvum
Cytoskeleton
Organelles
Parasites
Calcium
71 Citations (Scopus)

A pilot study of pentoxifylline for the treatment of primary sclerosing cholangitis

Bharucha, A. E., Jorgensen, R., Lichtman, S. N., La Russo, N. F. & Lindor, K. D., 2000, In : American Journal of Gastroenterology. 95, 9, p. 2338-2342 5 p.

Research output: Contribution to journalArticle

Pentoxifylline
Sclerosing Cholangitis
Tumor Necrosis Factor Receptors
Serum
Therapeutics
82 Citations (Scopus)

Apolipoproteins of high, low, and very low density lipoproteins in human bile

Sewell, R. B., Mao, S. J. T., Kawamoto, T. & La Russo, N. F., 1983, In : Journal of Lipid Research. 24, 4, p. 391-401 11 p.

Research output: Contribution to journalArticle

Plasma (human)
VLDL Lipoproteins
Apolipoproteins
Bile
Apoproteins
21 Citations (Scopus)

AQP4 Transfected into Mouse Cholangiocytes Promotes Water Transport in Biliary Epithelia

Splinter, P. L., Masyuk, A. I., Marinelli, R. A. & La Russo, N. F., Jan 2004, In : Hepatology. 39, 1, p. 109-116 8 p.

Research output: Contribution to journalArticle

Epithelium
Aquaporins
Water
Transcytosis
Mammals
38 Citations (Scopus)

Aquaporin-1 facilitates angiogenic invasion in the pathological neovasculature that accompanies cirrhosis

Huebert, R. C., Vasdev, M. M., Shergill, U., Das, A., Huang, B. Q., Charlton, M. R., La Russo, N. F. & Shah, V., Jul 2010, In : Hepatology. 52, 1, p. 238-248 11 p.

Research output: Contribution to journalArticle

Aquaporin 1
Fibrosis
Blister
Liver
Endothelial Cells
37 Citations (Scopus)

Aquaporin-1 promotes angiogenesis, fibrosis, and portal hypertension through mechanisms dependent on osmotically sensitive MicroRNAs

Huebert, R. C., Jagavelu, K., Hendrickson, H. I., Vasdev, M. M., Arab, J. P., Splinter, P. L., Trussoni, C. E., La Russo, N. F. & Shah, V., Oct 2011, In : American Journal of Pathology. 179, 4, p. 1851-1860 10 p.

Research output: Contribution to journalArticle

Aquaporin 1
Portal Hypertension
MicroRNAs
Fibrosis
Bile Ducts
42 Citations (Scopus)

Aquaporin-8 is involved in water transport in isolated superficial colonocytes from rat proximal colon

Laforenza, U., Cova, E., Gastaldi, G., Tritto, S., Grazioli, M., La Russo, N. F., Splinter, P. L., D'Adamo, P., Tosco, M. & Ventura, U., Oct 2005, In : Journal of Nutrition. 135, 10, p. 2329-2336 8 p.

Research output: Contribution to journalArticle

aquaporins
colon
Colon
Water Movements
Aquaporin 3
57 Citations (Scopus)

Aquaporins in the hepatobiliary system

Masyuk, A. I. & La Russo, N. F., Feb 2006, In : Hepatology. 43, 2 SUPPL. 1

Research output: Contribution to journalArticle

Aquaporins
Gluconeogenesis
Liver
Biliary Tract
Bile
32 Citations (Scopus)

Aquaporin water channels in liver: Their significance in bile formation

Marinelli, R. A. & La Russo, N. F., Nov 1997, In : Hepatology. 26, 5, p. 1081-1084 4 p.

Research output: Contribution to journalArticle

Aquaporins
Bile
Liver
76 Citations (Scopus)

Are patients with cirrhotic stage primary sclerosing cholangitis at risk for the development of hepatocellular cancer?

Harnois, D., Gores, G. J., Ludwig, J., Steers, J. L., La Russo, N. F. & Wiesner, R. H., Sep 1997, In : Journal of Hepatology. 27, 3, p. 512-516 5 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Liver Neoplasms
Hepatocellular Carcinoma
Liver Transplantation
Cholangiocarcinoma
242 Citations (Scopus)

A revised natural history model for primary sclerosing cholangitis

Kim, W. R., Therneau, T. M., Wiesner, R. H., Poterucha, J. J., Benson, J. T., Malinchoc, M., La Russo, N. F., Lindor, K. D. & Dickson, E. R., 2000, In : Mayo Clinic Proceedings. 75, 7, p. 688-694 7 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Natural History
Survival
Aspartate Aminotransferases
Bilirubin
48 Citations (Scopus)

ATP binding cassette transporter gene expression in rat liver progenitor cells

Ros, J. E., Roskams, T. A. D., Geuken, M., Havinga, R., Splinter, P. L., Petersen, B. E., La Russo, N. F., Van Der Kolk, D. M., Kuipers, F., Faber, K. N., Müller, M. & Jansen, P. L. M., Jul 1 2003, In : Gut. 52, 7, p. 1060-1067 8 p.

Research output: Contribution to journalArticle

ATP-Binding Cassette Transporters
Hepatocytes
Stem Cells
Gene Expression
Liver

AUTO-ANTICORPS ANTI-CYTOPLASME DES POLYNUCLEAIRES: UN MARQUEUR BIOLOGIQUE COMMUN A LA RECTOCOLITE HEMORRAGIQUE ET A LA CHOLANGITE SCLEROSANTE PRIMITIVE

Translated title of the contribution: Neutrophil cytoplasmic antibodies: A link between primary sclerosing cholangitis and ulcerative colitis: CommentDuerr, R. H., Targan, S. R., Landers, C. J., La Russo, N. F., Lindsay, K. L., Wiesner, R. H. & Shanahan, F., 1991, In : Gastroenterologie Clinique et Biologique. 15, 12, p. 990-991 2 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Ulcerative Colitis
Autoantibodies
Cytoplasm
Reference Values
54 Citations (Scopus)

Autosomal recessive polycystic kidney disease and congenital hepatic fibrosis: Summary statement of a First National Institutes of Health/Office of Rare Diseases conference

Gunay-Aygun, M., Avner, E. D., Bacallao, R. L., Choyke, P. L., Flynn, J. T., Germino, G. G., Guay-Woodford, L., Harris, P. C., Heller, T., Ingelfinger, J., Kaskel, F., Kleta, R., La Russo, N. F., Mohan, P., Pazour, G. J., Shneider, B. L., Torres, V., Wilson, P., Zak, C., Zhou, J. & 1 others, Gahl, W. A., Aug 2006, In : Journal of Pediatrics. 149, 2, p. 159-164 6 p.

Research output: Contribution to journalArticle

Autosomal Recessive Polycystic Kidney
Distal Kidney Tubule
Anticholesteremic Agents
Proximal Kidney Tubule
Phosphoric Diester Hydrolases
175 Citations (Scopus)

Bcl-2-dependent oxidation of pyruvate dehydrogenase-E2, a primary biliary cirrhosis autoantigen, during apoptosis

Odin, J. A., Huebert, R. C., Casciola-Rosen, L., La Russo, N. F. & Rosen, A., 2001, In : Journal of Clinical Investigation. 108, 2, p. 223-232 10 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Autoantigens
Pyruvic Acid
Oxidoreductases
Autoantibodies
104 Citations (Scopus)

Bcl-2 is overexpressed and alters the threshold for apoptosis in a cholangiocarcinoma cell line

Harnois, D., Que, F., Celli, A., La Russo, N. F. & Gores, G. J., Oct 1997, In : Hepatology. 26, 4, p. 884-890 7 p.

Research output: Contribution to journalArticle

B-Cell Leukemia
Cholangiocarcinoma
B-Cell Lymphoma
Apoptosis
Cell Line
Ice
ice
apoptosis
Chemical activation
Apoptosis
74 Citations (Scopus)

Bilary excretion of iron from hepatocyte lysosomes in the rat. A major excretory pathway in experimental iron overload

LeSage, G. D., Kost, L. J., Barham, S. S. & La Russo, N. F., 1986, In : Journal of Clinical Investigation. 77, 1, p. 90-97 8 p.

Research output: Contribution to journalArticle

Iron Overload
Lysosomes
Hepatocytes
Iron
Bile
19 Citations (Scopus)

Biliary and renal excretion, hepatic metabolism, and hepatic subcellular distribution of metronidazole in the rat

La Russo, N. F., Lindmark, D. G. & Müller, M., 1978, In : Biochemical Pharmacology. 27, 18, p. 2247-2254 8 p.

Research output: Contribution to journalArticle

Metronidazole
Metabolism
Rats
Liver
Bile
91 Citations (Scopus)

Biliary copper excretion by hepatocyte lysosomes in the rat. Major excretory pathway in experimental copper overload

Gross, J. B., Myers, B. M., Kost, L. J., Kuntz, S. M. & La Russo, N. F., 1989, In : Journal of Clinical Investigation. 83, 1, p. 30-39 10 p.

Research output: Contribution to journalArticle

Lysosomes
Copper
Hepatocytes
Hepatobiliary Elimination
Liver
75 Citations (Scopus)

Biliary dysgenesis in the PCK rat, an orthologous model of autosomal recessive polycystic kidney disease

Masyuk, T. V., Huang, B. Q., Masyuk, A. I., Ritman, E. L., Torres, V., Wang, X., Harris, P. C. & La Russo, N. F., Nov 2004, In : American Journal of Pathology. 165, 5, p. 1719-1730 12 p.

Research output: Contribution to journalArticle

Autosomal Recessive Polycystic Kidney
Cilia
Liver
Bile Ducts
Cysts
14 Citations (Scopus)
Apolipoproteins B
LDL Lipoproteins
Bile
Lipoproteins
Lipids
145 Citations (Scopus)

Biliary exosomes influence cholangiocyte regulatory mechanisms and proliferation through interaction with primary cilia

Masyuk, A. I., Huang, B. Q., Ward, C. J., Gradilone, S. A., Banales, J. M., Masyuk, T. V., Radtke, B., Splinter, P. L. & La Russo, N. F., Oct 2010, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 299, 4

Research output: Contribution to journalArticle

Exosomes
Cilia
Bile
Intrahepatic Bile Ducts
Immunoelectron Microscopy
55 Citations (Scopus)

Biliary proteins: Assessment of quantitative techniques and comparison in gallstone and nongallstone subjects

Yamazaki, K., Powers, S. P. & La Russo, N. F., 1988, In : Journal of Lipid Research. 29, 8, p. 1055-1063 9 p.

Research output: Contribution to journalArticle

Gallstones
Bile
Fluorescamine
Proteins
Assays
23 Citations (Scopus)

Biliary secretion of copper in healthy man. Quantitation by an intestinal perfusion technique

van Berge Henegouwen, G. P., Tangedahl, T. N., Hofmann, A. F., Northfield, T. C., La Russo, N. F. & McCall, J. T., 1977, In : Gastroenterology. 72, 6, p. 1228-1231 4 p.

Research output: Contribution to journalArticle

Copper
Perfusion
Bile
Bile Acids and Salts
Gallbladder
2 Citations (Scopus)

Biliary tract physiology

Prall, R. T. & La Russo, N. F., 2000, In : Current Opinion in Gastroenterology. 16, 5, p. 432-436 5 p.

Research output: Contribution to journalArticle

Biliary Tract
Bile
Bile Ducts
Bile Acids and Salts
Nervous System
5 Citations (Scopus)

Biliary tract physiology

Prall, R. T. & La Russo, N. F., 1999, In : Current Opinion in Gastroenterology. 15, 5, p. 423-429 7 p.

Research output: Contribution to journalArticle

Biliary Tract
Bile
Bile Ducts
Bile Acids and Salts
Electrolytes
17 Citations (Scopus)

Biological characteristics of primary cultures of human gallbladder epithelial cells

Hoerl, B. J., Vroman, B. T., Kasperbauer, J., La Russo, N. F. & Scott, R. E., 1992, In : Laboratory Investigation. 66, 2, p. 243-250 8 p.

Research output: Contribution to journalArticle

Gallbladder
Epithelial Cells
Cell Culture Techniques
Keratin-19
Collagen Type IV
1 Citation (Scopus)

B-type natriuretic peptide overexpression ameliorates hepatorenal fibrocystic disease in a rat model of polycystic kidney disease

Holditch, S. J., Schreiber, C. A., Harris, P. C., La Russo, N. F., Ramirez-Alvarado, M., Cataliotti, A., Torres, V. & Ikeda, Y. H., Jul 22 2016, (Accepted/In press) In : Kidney International.

Research output: Contribution to journalArticle

Polycystic Kidney Diseases
Brain Natriuretic Peptide
Vasopressins
Disease Progression
Kidney