• 27577 Citations
  • 95 Scopus h-Index
1973 …2020

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Hepatic extraction of renin: Quantitation and characterization in the isolated perfused rat liver

Keiser, J. A., Romero, J. C., Kost, L. J. & Larusso, N. F., Jan 1 1987, In : Hepatology. 7, 6, p. 1254-1261 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Hepatic Drug Metabolism and Malignancy

Larusso, N. F., Oct 4 1976, In : JAMA: The Journal of the American Medical Association. 236, 14, p. 1612-1613 2 p.

Research output: Contribution to journalArticle

Hepatic cystogenesis is associated with abnormal expression and location of ion transporters and water channels in an animal model of autosomal recessive polycystic kidney disease

Banales, J. M., Masyuk, T. V., Bogert, P. S., Huang, B. Q., Gradilone, S. A., Lee, S. O., Stroope, A. J., Masyuk, A. I., Medina, J. F. & LaRusso, N. F., Dec 2008, In : American Journal of Pathology. 173, 6, p. 1637-1646 10 p.

Research output: Contribution to journalArticle

52 Scopus citations

Hepatic artery and portal vein remodeling in rat liver: Vascular response to selective cholangiocyte proliferation

Masyuk, T. V., Ritman, E. L. & LaRusso, N. F., Apr 1 2003, In : American Journal of Pathology. 162, 4, p. 1175-1182 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Health reform: A community experience using design research as a guide

Severson, M. A., Wood, D. L., Chastain, C. N., Lee, L. G., Rees, A. C., Agerter, D. C., Holtz, C. P., Broers, J. K., Savoleinen, K. H., Spurrier, B. R. & Larusso, N. F., Oct 2011, In : Mayo Clinic proceedings. 86, 10, p. 973-980 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

HDAC6 is overexpressed in cystic cholangiocytes and its inhibition reduces cystogenesis

Gradilone, S. A., Habringer, S., Masyuk, T. V., Howard, B. N., Masyuk, A. I. & Larusso, N. F., Mar 1 2014, In : American Journal of Pathology. 184, 3, p. 600-608 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

HDAC6 inhibition restores ciliary expression and decreases tumor growth

Gradilone, S. A., Radtke, B. N., Bogert, P. S., Huang, B. Q., Gajdos, G. B. & LaRusso, N. F., Apr 1 2013, In : Cancer research. 73, 7, p. 2259-2270 12 p.

Research output: Contribution to journalArticle

83 Scopus citations

Hail to the chief-Keith Lindor, our new AASLD president

Shah, V., Gores, G. J. & La Russo, N. F., Feb 1 2016, In : Hepatology. 63, 2, p. 357-359 3 p.

Research output: Contribution to journalArticle

GUDC inhibits cytochrome c release from human cholangiocyte mitochondria

Que, F. G., Phan, V. A., Phan, V. H., Larusso, N. F. & Gores, G. J., May 15 1999, In : Journal of Surgical Research. 83, 2, p. 100-105 6 p.

Research output: Contribution to journalArticle

24 Scopus citations
119 Scopus citations

Glucagon induces the plasma membrane insertion of functional aquaporin-8 water channels in isolated rat hepatocytes

Gradilone, S. A., García, F., Huebert, R. C., Tietz, P. S., Larocca, M. C., Kierbel, A., Carreras, F. I., LaRusso, N. F. & Marinelli, R. A., Jun 1 2003, In : Hepatology. 37, 6, p. 1435-1441 7 p.

Research output: Contribution to journalArticle

72 Scopus citations

Gene expression and polarized distribution of membrane acid/base carriers in a differentiated rat cholangiocyte cell line (NRC-1)

Spirli, C., Granato, A., Zsembery, A., Okolicsanyi, L., LaRusso, N. F. & Strazzabosco, M., Dec 1 1997, In : Italian Journal of Gastroenterology and Hepatology. 29, 1, 1 p.

Research output: Contribution to journalArticle

Gastroenterology's editors-in-chief: historical and personal perspectives of their editorships.

Fordtran, J. S., Goyal, R. K., Feldman, M., Soll, A. H., Trier, J. S., Ockner, R. K., Larusso, N. F., Podolsky, D. K., Brenner, D. A., Rustgi, A. K. & Omary, M. B., Jul 2013, In : Gastroenterology. 145, 1, p. 16-31 16 p.

Research output: Contribution to journalArticle

2 Scopus citations

Gallbladder disease in patients with primary sclerosing cholangitis

Brandt, D. J., MacCarty, R. L., Charboneau, J. W., LaRusso, N. F., Wiesner, R. H. & Ludwig, J., Jan 1 1988, In : American Journal of Roentgenology. 150, 3, p. 571-574 4 p.

Research output: Contribution to journalArticle

71 Scopus citations

Fusion innovation

La Russo, N. F., Spurrier, B. & Farrugia, G., Jan 1 2015, In : T and D. 69, 1

Research output: Contribution to journalArticle

Functional polarity of Na+/H+ and Cl-/HCO3/- exchangers in a rat cholangiocyte cell line

Spirlì, C., Granato, A., Zsembery, À., Anglani, F., Okolicsànyi, L., LaRusso, N. F., Crepaldi, G. & Strazzabosco, M., Dec 1 1998, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 275, 6 38-6, p. G1236-G1245

Research output: Contribution to journalArticle

40 Scopus citations
11 Scopus citations

Fluid-phase endocytosis by intrahepatic bile duct epithelial cells isolated from normal rat liver

Ishii, M., Vroman, B. & LaRusso, N. F., Jan 1 1990, In : Journal of Histochemistry and Cytochemistry. 38, 4, p. 515-524 10 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

Familial Occurrence of Primary Sclerosing Cholangitis and Ulcerative Colitis

Quigley, E. M. M., LaRusso, N. F., Ludwig, J., MacSween, R. N. M., Birnie, G. G. & Watkinson, G., Jan 1 1983, In : Gastroenterology. 85, 5, p. 1160-1165 6 p.

Research output: Contribution to journalArticle

Open Access
110 Scopus citations

Expression of aquaporin-4 water channels in rat cholangiocytes

Marinelli, R. A., Pham, L. D., Tietz, P. S. & LaRusso, N. F., Jan 1 2000, In : Hepatology. 31, 6, p. 1313-1317 5 p.

Research output: Contribution to journalArticle

50 Scopus citations

Expression and subcellular localization of aquaporin water channels in the polarized hepatocyte cell line, WIF-B

Gradilone, S. A., Tietz, P. S., Splinter, P. L., Marinelli, R. A. & LaRusso, N. F., Aug 18 2005, In : BMC Physiology. 5

Research output: Contribution to journalArticle

28 Scopus citations

Expression and localization of aquaporin water channels in rat hepatocytes. Evidence for a role in canalicular bile secretion

Huebert, R. C., Splinter, P. L., Garcia, F., Marinelli, R. A. & Larusso, N. F., Jun 21 2002, In : Journal of Biological Chemistry. 277, 25, p. 22710-22717 8 p.

Research output: Contribution to journalArticle

122 Scopus citations

Evidence suggesting lysosomes may modulate effects of estrogens on the liver

Lopez Del Pino, V., Kost, L. & LaRusso, N. F., Jan 1 1980, In : Gastroenterology. 78, 5 II, 1 p.

Research output: Contribution to journalArticle

ETS proto-oncogene 1 transcriptionally up-regulates the cholangiocyte senescence-associated protein cyclin-dependent kinase inhibitor 2A

O'Hara, S. P., Splinter, P. L., Trussoni, C. E., Lorenzo Pisarello, M. J., Loarca, L., Splinter, N. S., Schutte, B. F. & La Russo, N. F., Mar 24 2017, In : Journal of Biological Chemistry. 292, 12, p. 4833-4846 14 p.

Research output: Contribution to journalArticle

10 Scopus citations

Ethynylestradiol inhibits bile flow and biliary protein secretion but stimulates release of lysosomal enzymes into bile

Lopez del Pino, V., Carter, J. & LaRusso, N. F., Jan 1 1979, In : Gastroenterology. 76, 5 II, 1 p.

Research output: Contribution to journalArticle

Epigenetics in the Primary Biliary Cholangitis and Primary Sclerosing Cholangitis

Cheung, A. C., La Russo, N. F., Gores, G. J. & Lazaridis, K. N., May 1 2017, In : Seminars in Liver Disease. 37, 2, p. 159-174 16 p.

Research output: Contribution to journalArticle

9 Scopus citations

Epidermal growth factor protects the apical junctional complexes from hydrogen peroxide in bile duct epithelium

Guntaka, S. R., Samak, G., Seth, A., Larusso, N. F. & Rao, R., Sep 1 2011, In : Laboratory Investigation. 91, 9, p. 1396-1409 14 p.

Research output: Contribution to journalArticle

20 Scopus citations

Enzymatic determination of total 3αhydroxy bile acids in faeces: Validation in healthy subjects of a rapid method suitable for clinical routine purpose

Malchow-Møller, A., Arffmann, S., Larusso, N. F. & Krag, E., Jan 1 1982, In : Scandinavian Journal of Gastroenterology. 17, 3, p. 331-333 3 p.

Research output: Contribution to journalArticle

28 Scopus citations

Enhanced autoreactivity of T‐lymphocytes in primary sclerosing cholangitis

Lindor, K. D., Wiesner, R. H., Larusso, N. F. & Homburger, H. A., Jan 1 1987, In : Hepatology. 7, 5, p. 884-888 5 p.

Research output: Contribution to journalArticle

57 Scopus citations

Engineered measles virus as a novel oncolytic viral therapy system for hepatocellular carcinoma

Blechacz, B., Splinter, P. L., Greiner, S., Myers, R., Peng, K. W., Federspiel, M. J., Russell, S. J. & LaRusso, N. F., Dec 1 2006, In : Hepatology. 44, 6, p. 1465-1477 13 p.

Research output: Contribution to journalArticle

81 Scopus citations

Emerging pharmacologic therapies for primary sclerosing cholangitis

Cheung, A. C., Lazaridis, K. N., La Russo, N. F. & Gores, G. J., Mar 2 2017, (Accepted/In press) In : Current Opinion in Gastroenterology.

Research output: Contribution to journalArticle

6 Scopus citations

Elevated Circulating Immune Complexes in Primary Sclerosing Cholangitis

Bodenheimer, H. C., Larusso, N. F., Thayer, W. R., Charland, C., Staples, P. J. & Ludwig, J., 1983, In : Hepatology. 3, 2, p. 150-154 5 p.

Research output: Contribution to journalArticle

117 Scopus citations

Electropermeabilization: Getting inside the cell to study autophagy

Yamazaki, K. & Larusso, N. F., Jan 1 1988, In : Hepatology. 8, 2, p. 418-419 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Efficacy of 4 Years of Octreotide Long-Acting Release Therapy in Patients with Severe Polycystic Liver Disease

Hogan, M. C., Masyuk, T., Bergstralh, E., Li, B., Kremers, W. K., Vaughan, L. E., Ihrke, A., Severson, A. L., Irazabal Mira, M., Glockner, J., La Russo, N. F. & Torres, V., Aug 1 2015, In : Mayo Clinic Proceedings. 90, 8, p. 1030-1037 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Efficacy and safety of transarterial radioembolization versus chemoembolization in patients with hepatocellular carcinoma

Moreno-Luna, L. E., Yang, J. D., Sanchez, W., Paz-Fumagalli, R., Harnois, D. M., Mettler, T. A., Gansen, D. N., De Groen, P. C., Lazaridis, K. N., Narayanan Menon, K. V., Larusso, N. F., Alberts, S. R., Gores, G. J., Fleming, C. J., Slettedahl, S. W., Harmsen, W. S., Therneau, T. M., Wiseman, G. A., Andrews, J. C. & Roberts, L. R., Jun 1 2013, In : Cardiovascular and Interventional Radiology. 36, 3, p. 714-723 10 p.

Research output: Contribution to journalArticle

75 Scopus citations

Efficacy and safety of curcumin in primary sclerosing cholangitis: an open label pilot study

Eaton, J. E., Nelson, K. M., Gossard, A. A., Carey, E. J., Tabibian, J. H., Lindor, K. D. & LaRusso, N. F., May 4 2019, In : Scandinavian Journal of Gastroenterology. 54, 5, p. 633-639 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Effects of Acute Bile Acid Administration on Biliary Lipid Secretion in Healthy Volunteers

Sama, C., LaRusso, N. F., Lopez del Pino, V. & Thistle, J. L., Jan 1 1982, In : Gastroenterology. 82, 3, p. 515-525 11 p.

Research output: Contribution to journalArticle

Open Access
33 Scopus citations

Effect of proctocolectomy for chronic ulcerative colitis on the natural history of primary sclerosing cholangitis

Cangemi, J. R., Wiesner, R. H., Beaver, S. J., Ludwig, J., MacCarty, R. L., Dozois, R. R., Zinsmeister, A. R. & La Russo, N. F., Jan 1 1989, In : Gastroenterology. 96, 3, p. 790-794 5 p.

Research output: Contribution to journalArticle

124 Scopus citations

Effect of primary bile acid ingestion on bile acid metabolism and biliary lipid secretion in gallstone patients

LaRusso, N. F., Hoffman, N. E., Hofmann, A. F., Northfield, T. C. & Thistle, J. L., Dec 1 1975, In : Gastroenterology. 69, 6, p. 1301-1314 14 p.

Research output: Contribution to journalArticle

110 Scopus citations

Effect of Litholytic Bile Acids on Cholesterol Absorption in Gallstone Patients

LaRusso, N. F. & Thistle, J. L., Jan 1 1983, In : Gastroenterology. 84, 2, p. 265-271 7 p.

Research output: Contribution to journalArticle

Open Access
25 Scopus citations

Effect of Deoxycholic Acid Ingestion on Bile Acid Metabolism and Biliary Lipid Secretion in Normal Subjects

LaRusso, N. F., Szczepanik, P. A. & Hofmann, A. F., Jan 1 1977, In : Gastroenterology. 72, 1, p. 132-140 9 p.

Research output: Contribution to journalArticle

Open Access
85 Scopus citations

Effect of deoxycholic, chenodeoxycholic, and cholic acids on intestinal absorption of cholesterol in humans

Sama, C. & LaRusso, N. F., Jan 1 1982, In : Mayo Clinic proceedings. 57, 1, p. 44-50 7 p.

Research output: Contribution to journalArticle

22 Scopus citations
Open Access
33 Scopus citations

Effect of acute administration of bile acids on biliary lipid secretion in man

Sama, C., La Russo, N. F., Lopez, V. & Thistle, J. L., Jan 1 1981, In : Italian Journal of Gastroenterology. 13, 1, p. 73-74 2 p.

Research output: Contribution to journalArticle

Effective dissolution of biliary duct stones by intraductal infusion of mono octanoin

Thistle, J. L., Carlson, G. L., LaRusso, N. F. & Hofmann, A. F., Jan 1 1978, In : Gastroenterology. 74, 5 II, 1 p.

Research output: Contribution to journalArticle

14 Scopus citations
134 Scopus citations

Dynamic measurements of the acute and chronic effects of lysosomotropic agents on hepatocyte lysosomal pH using flow cytometry

Myers, B. M., Tietz, P. S., Tarara, J. E. & Larusso, N. F., Nov 1995, In : Hepatology. 22, 5, p. 1519-1526 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Doublecortin domain containing protein 2 (DCDC2) genetic variants in primary sclerosing cholangitis

Cheung, A. C., Juran, B. D., Moore, R. M., La Russo, N. F. & Lazaridis, K. N., 2017, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

1 Scopus citations

Diurnal serum levels of primary conjugated bile acids. Assessment by specific radioimmunoassays for conjugates of cholic and chenodeoxycholic acid

Schalm, S. W., LaRusso, N. F., Hofmann, A. F., Hoffman, N. E., van Berge-Henegouwen, G. P. & Korman, M. G., Jan 1 1978, In : Unknown Journal. 19, 11, p. 1006-1014 9 p.

Research output: Contribution to journalArticle

Open Access
54 Scopus citations

Distribution of Cryptosporidium parvum sporozoite apical organelles during attachment to and internalization by cultured biliary epithelial cells

O'Hara, S. P., Huang, B. Q., Chen, X. M., Nelson, J. & LaRusso, N. F., Oct 1 2005, In : Journal of Parasitology. 91, 5, p. 995-999 5 p.

Research output: Contribution to journalArticle

8 Scopus citations