• 27361 Citations
  • 94 Scopus h-Index
1973 …2020

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Opisthorchis viverrini excretory/secretory products induce toll-like receptor 4 upregulation and production of interleukin 6 and 8 in cholangiocyte

Ninlawan, K., O'Hara, S. P., Splinter, P. L., Yongvanit, P., Kaewkes, S., Surapaitoon, A., La Russo, N. F. & Sripa, B., Dec 2010, In : Parasitology International. 59, 4, p. 616-621 6 p.

Research output: Contribution to journalArticle

44 Scopus citations
196 Scopus citations

Nonoperative dilatation of dominant strictures in primary sclerosing cholangitis

May, G. R., Bender, C. E., La Russo, N. F. & Wiesner, R. H., 1985, In : American Journal of Roentgenology. 145, 5, p. 1061-1064 4 p.

Research output: Contribution to journalArticle

81 Scopus citations

Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes

Jaiswal, M., La Russo, N. F., Shapiro, R. A., Billiar, T. R. & Gores, G. J., 2001, In : Gastroenterology. 120, 1, p. 190-199 10 p.

Research output: Contribution to journalArticle

152 Scopus citations
232 Scopus citations

NFκB p50-CCAAT/enhancer-binding protein β (C/EBPβ)-mediated transcriptional repression of microRNA let-7i following microbial infection

O'Hara, S. P., Splinter, P. L., Gajdos, G. B., Trussoni, C. E., Fernandez-Zapico, M. E., Chen, X. M. & La Russo, N. F., Jan 1 2010, In : Journal of Biological Chemistry. 285, 1, p. 216-225 10 p.

Research output: Contribution to journalArticle

81 Scopus citations

Neutrophil cytoplasmic antibodies: A link between primary sclerosing cholangitis and ulcerative colitis

Duerr, R. H., Targan, S. R., Landers, C. J., La Russo, N. F., Lindsay, K. L., Wiesner, R. H. & Shanahan, F., 1991, In : Gastroenterology. 100, 5 PART 1, p. 1385-1391 7 p.

Research output: Contribution to journalArticle

280 Scopus citations

Multiple TLRs are expressed in human cholangiocytes and mediate host epithelial defense responses to Cryptosporidium parvum via activation of NF-κB

Chen, X. M., O'Hara, S. P., Nelson, J. B., Splinter, P. L., Small, A. J., Tietz, P. S., Limper, A. H. & La Russo, N. F., Dec 1 2005, In : Journal of Immunology. 175, 11, p. 7447-7456 10 p.

Research output: Contribution to journalArticle

147 Scopus citations

Morphology, physiology, and biochemistry of biliary epithelia

La Russo, N. F., Jan 1996, In : Toxicologic Pathology. 24, 1, p. 84-89 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Morphologic features of chronic hepatitis associated with primary sclerosing cholangitis and chronic ulcerative colitis

Ludwig, J., Barham, S. S., La Russo, N. F., Elveback, L. R., Wiesner, R. H. & McCall, J. T., 1981, In : Hepatology. 1, 6, p. 632-640 9 p.

Research output: Contribution to journalArticle

277 Scopus citations

Morphologic demonstration of receptor-mediated endocytosis of epidermal growth factor by isolated bile duct epithelial cells

Ishii, M., Vroman, B. & La Russo, N. F., 1990, In : Gastroenterology. 98, 5 PART 1, p. 1284-1291 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Morphological, molecular, and functional heterogeneity of cholangiocytes from normal rat liver

Alpini, G., Roberts, S., Kuntz, S. M., Ueno, Y., Gubba, S., Podila, P. V., LeSage, G. & La Russo, N. F., 1996, In : Gastroenterology. 110, 5, p. 1636-1643 8 p.

Research output: Contribution to journalArticle

182 Scopus citations

Monooctanoin, a dissolution agent for retained cholesterol bile duct stones: Physical properties and clinical application

Thistle, J. L., Carlson, G. L., Hofmann, A. F., La Russo, N. F., MacCarty, R. L., Flynn, G. L., Higuchi, W. I. & Babayan, V. K., 1980, In : Gastroenterology. 78, 5 PART 1, p. 1016-1022 7 p.

Research output: Contribution to journalArticle

100 Scopus citations

Molecular studies of ceruloplasmin deficiency in Wilson's disease

Czaja, M. J., Weiner, F. R., Schwarzenberg, S. J., Sternlieb, I., Scheinberg, I. H., Van Thiel, D. H., La Russo, N. F., Giambrone, M. A., Kirschner, R., Koschinsky, M. L., MacGillivray, R. T. A. & Zern, M. A., 1987, In : Journal of Clinical Investigation. 80, 4, p. 1200-1204 5 p.

Research output: Contribution to journalArticle

43 Scopus citations

Molecular and functional heterogeneity of cholangiocytes from rat liver after bile duct ligation

Alpini, G., Ulrich, C., Roberts, S., Phillips, J. O., Ueno, Y., Podila, P. V., Colegio, O., LeSage, G. D., Miller, L. J. & La Russo, N. F., Feb 1997, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 272, 2 35-2

Research output: Contribution to journalArticle

116 Scopus citations

Modified culture conditions enhance expression of differentiated phenotypic properties of normal rat cholangiocytes

Salter, K. D., Roman, R. M., La Russo, N. F., Fitz, J. G. & Doctor, R. B., 2000, In : Laboratory Investigation. 80, 11, p. 1775-1778 4 p.

Research output: Contribution to journalArticle

26 Scopus citations

Milder disease stage in patients with primary biliary cholangitis over a 44-year period: A changing natural history

on behalf of the GLOBAL PBC Study Group, May 1 2018, In : Hepatology. 67, 5, p. 1920-1930 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Microtubule modulation of biliary excretion of endogenous and exogenous hepatic lysosomal constituents.

Sewell, R. B., Barham, S. S., Zinsmeister, A. R. & La Russo, N. F., Jan 1984, In : The American journal of physiology. 246, 1 Pt 1

Research output: Contribution to journalArticle

21 Scopus citations

MicroRNAs in cholangiociliopathies

Masyuk, T., Masyuk, A. & La Russo, N. F., May 1 2009, In : Cell Cycle. 8, 9, p. 1324-1328 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

MicroRNAs and benign biliary tract diseases

Gradilone, S. A., O'Hara, S. P., Masyuk, T. V., Pisarello, M. J. L. & La Russo, N. F., Feb 1 2015, In : Seminars in Liver Disease. 35, 1, p. 26-35 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

MicroRNAs: Key Modulators of Posttranscriptional Gene Expression

O'Hara, S. P., Mott, J. L., Splinter, P. L., Gores, G. J. & La Russo, N. F., Jan 2009, In : Gastroenterology. 136, 1, p. 17-25 9 p.

Research output: Contribution to journalArticle

72 Scopus citations

MicroRNA-513 regulates B7-H1 translation and is involved in IFN-γ-induced B7-H1 expression in cholangiocytes

Gong, A. Y., Zhou, R., Hu, G., Li, X., Splinter, P. L., O'Hara, S. P., La Russo, N. F., Soukup, G. A., Dong, H. M. & Chen, X. M., Feb 1 2009, In : Journal of Immunology. 182, 3, p. 1325-1333 9 p.

Research output: Contribution to journalArticle

129 Scopus citations

MicroRNA-506 promotes primary biliary cholangitis-like features in cholangiocytes and immune activation

Erice, O., Munoz-Garrido, P., Vaquero, J., Perugorria, M. J., Fernandez-Barrena, M. G., Saez, E., Santos-Laso, A., Arbelaiz, A., Jimenez-Agüero, R., Fernandez-Irigoyen, J., Santamaria, E., Torrano, V., Carracedo, A., Ananthanarayanan, M., Marzioni, M., Prieto, J., Beuers, U., Oude Elferink, R. P., La Russo, N. F., Bujanda, L. & 2 others, Marin, J. J. G. & Banales, J. M., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

19 Scopus citations

MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3

Selaru, F. M., Olaru, A. V., Kan, T., David, S., Cheng, Y., Mori, Y., Yang, J., Paun, B., Jin, Z., Agarwal, R., Hamilton, J. P., Abraham, J., Georgiades, C., Alvarez, H., Vivekanandan, P., Yu, W., Maitra, A., Torbenson, M., Thuluvath, P. J., Gores, G. J. & 3 others, La Russo, N. F., Hruban, R. & Meltzer, S. J., May 2009, In : Hepatology. 49, 5, p. 1595-1601 7 p.

Research output: Contribution to journalArticle

208 Scopus citations

MicroRNA15a modulates expression of the cell-cycle regulator Cdc25A and affects hepatic cystogenesis in a rat model of polycystic kidney disease

Lee, S. O., Masyuk, T., Splinter, P., Banales, J. M., Masyuk, A., Stroope, A. & La Russo, N. F., Nov 3 2008, In : Journal of Clinical Investigation. 118, 11, p. 3714-3724 11 p.

Research output: Contribution to journalArticle

124 Scopus citations

MicroRNA (miR)-433 and miR-22 dysregulations induce histone-deacetylase-6 overexpression and ciliary loss in cholangiocarcinoma

Mansini, A. P., Lorenzo Pisarello, M. J., Thelen, K. M., Cruz-Reyes, M., Peixoto, E., Jin, S., Howard, B. N., Trussoni, C. E., Gajdos, G. B., La Russo, N. F., Perugorria, M. J., Banales, J. M. & Gradilone, S. A., Aug 1 2018, In : Hepatology. 68, 2, p. 561-573 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Micro-computed tomography and nuclear magnetic resonance imaging for noninvasive, live-mouse cholangiography

Tabibian, J. H., Macura, S. I., O'Hara, S. P., Fidler, J. L., Glockner, J., Takahashi, N., Lowe, V., Kemp, B. J., Mishra, P. K., Tietz, P. S., Splinter, P. L., Trussoni, C. E. & La Russo, N. F., Jun 2013, In : Laboratory Investigation. 93, 6, p. 733-743 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Microbiome-immune interactions and liver disease

Tabibian, J. H., Varghese, C., O'Hara, S. P. & La Russo, N. F., Apr 1 2015, In : Clinical Liver Disease. 5, 4, p. 83-85 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Metabolomic profiling of portal blood and bile reveals metabolic signatures of primary sclerosing cholangitis

Tietz-Bogert, P. S., Kim, M., Cheung, A., Tabibian, J. H., Heimbach, J. K., Rosen, C. B., Nandakumar, M., Lazaridis, K. N., La Russo, N. F., Sung, J. & O’hara, S. P., Oct 16 2018, In : International Journal of Molecular Sciences. 19, 10, 3188.

Research output: Contribution to journalArticle

4 Scopus citations

Membrane microdomains in hepatocytes: Potential target areas for proteins involved in canalicular bile secretion

Tietz, P., Jefferson, J., Pagano, R. & La Russo, N. F., 2005, In : Journal of Lipid Research. 46, 7, p. 1426-1432 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Medical progress: Biliary tract cancers

De Groen, P. C., Gores, G. J., La Russo, N. F., Gunderson, L. L. & Nagorney, D. M., Oct 28 1999, In : New England Journal of Medicine. 341, 18, p. 1368-1378 11 p.

Research output: Contribution to journalArticle

789 Scopus citations

Manifestations of nonsuppurative cholangitis in chronic hepatobiliary diseases: Morphologic spectrum, clinical correlations and terminology

Ludwig, J., Czaja, A. J., Dickson, E. R., La Russo, N. F. & Wiesner, R. H., 1984, In : Liver. 4, 2, p. 105-116 12 p.

Research output: Contribution to journalArticle

103 Scopus citations

Magnetic resonance cholangiography in patients with biliary disease: Its role in primary sclerosing cholangitis

Angulo, P., Pearce, D. H., Johnson, C. D., Henry, J. J., La Russo, N. F., Petersen, B. T. & Lindor, K. D., 2000, In : Journal of Hepatology. 33, 4, p. 520-527 8 p.

Research output: Contribution to journalArticle

132 Scopus citations

Macrophages contribute to the pathogenesis of sclerosing cholangitis in mice

Guicciardi, M. E., Trussoni, C. E., Krishnan, A., Bronk, S. F., Lorenzo Pisarello, M. J., O'Hara, S. P., Splinter, P. L., Gao, Y., Vig, P., Revzin, A., La Russo, N. F. & Gores, G. J., Jan 1 2018, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

19 Scopus citations

Lysosomal enzymes in biological fluids. Physiologic and pathophysiologic significance

La Russo, N. F., 1979, In : Digestive Diseases and Sciences. 24, 3, p. 177-179 3 p.

Research output: Contribution to journalArticle

10 Scopus citations

Lymphocyte subsets in primary sclerosing cholangitis

Lindor, K. D., Wiesner, R. H., Katzmann, J. A., La Russo, N. F. & Beaver, S. J., Jul 1987, In : Digestive Diseases and Sciences. 32, 7, p. 720-725 6 p.

Research output: Contribution to journalArticle

54 Scopus citations

Long-term results of patients undergoing liver transplantation for primary sclerosing cholangitis

Graziadei, I. W., Wiesner, R. H., Marotta, P. J., Porayko, M. K., Eileen Hay, J., Charlton, M. R., Poterucha, J. J., Rosen, C. B., Gores, G. J., La Russo, N. F. & Krom, R. A. F., 1999, In : Hepatology. 30, 5, p. 1121-1127 7 p.

Research output: Contribution to journalArticle

269 Scopus citations

Localized glucose and water influx facilitates Cryptosporidium parvum cellular invasion by means of modulation of host-cell membrane protrusion

Chen, X. M., O'Hara, S. P., Huang, B. Q., Splinter, P. L., Nelson, J. B. & La Russo, N. F., May 3 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 18, p. 6338-6343 6 p.

Research output: Contribution to journalArticle

69 Scopus citations

Liver transplantation for primary sclerosing cholangitis: Impact of risk factors on outcome

Wiesner, R. H., Porayko, M. K., Hay, J. E., La Russo, N. F., Steers, J. L., Krom, R. A. F. & Dickson, E. R., 1996, In : Liver Transplantation and Surgery. 2, 5 SUPPL. 1, p. 99-108 10 p.

Research output: Contribution to journalArticle

38 Scopus citations
93 Scopus citations

Lack of metabolic effects of cholecystokinin on hepatocytes

Kost, L. J., Gores, G. J., Sayles, J. M., Miller, L. J., Lemasters, J. J., Herman, B. & La Russo, N. F., Aug 1990, In : Hepatology. 12, 2, p. 301-305 5 p.

Research output: Contribution to journalArticle

12 Scopus citations
53 Scopus citations

Is primary sclerosing cholangitis a progressive disease or not?

Wiesner, R. H., Grambsch, P., La Russo, N. F. & Dickson, E. R., Jul 1988, In : Hepatology. 8, 4, p. 970-972 3 p.

Research output: Contribution to journalArticle

17 Scopus citations

Is primary sclerosing cholangitis a bad disease?

La Russo, N. F., Wiesner, R. H. & Ludwig, J., 1987, In : Gastroenterology. 92, 6, p. 2031-2033 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Isolation of the microtubule-vesicle motor kinesin from rat liver: Selective inhibition by cholestatic bile acids

Marks, D. L., La Russo, N. F. & Mc Niven, M. A., 1995, In : Gastroenterology. 108, 3, p. 824-833 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Isolation of primary cilia for morphological analysis.

Huang, B., Masyuk, T. & La Russo, N. F., 2009, In : Methods in Cell Biology. 94, p. 103-115 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Isolation and morphologic characterization of bile duct epithelial cells from normal rat liver

Ishii, M., Vroman, B. & La Russo, N. F., 1989, In : Gastroenterology. 97, 5, p. 1236-1247 12 p.

Research output: Contribution to journalArticle

177 Scopus citations

Isolation and characterization of rat cholangiocyte vesicles enriched in apical or basolateral plasma membrane domains

Tietz, P. S., Holman, R. T., Miller, L. J. & La Russo, N. F., 1995, In : Biochemistry. 34, 47, p. 15436-15443 8 p.

Research output: Contribution to journalArticle

54 Scopus citations

Isolation and characterization of lipid microdomains from apical and basolateral plasma membranes of rat hepatocytes

Mazzone, A., Tietz, P., Jefferson, J., Pagano, R. & La Russo, N. F., Feb 2006, In : Hepatology. 43, 2, p. 287-296 10 p.

Research output: Contribution to journalArticle

62 Scopus citations

Isolation and characterization of cholangiocyte primary cilia

Huang, B. Q., Masyuk, T. V., Muff, M. A., Tietz, P. S., Masyuk, A. I. & La Russo, N. F., 2006, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 291, 3

Research output: Contribution to journalArticle

62 Scopus citations