• 26897 Citations
  • 93 Scopus h-Index
1973 …2019
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Research Output 1973 2019

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71 Citations (Scopus)

MicroRNAs: Key Modulators of Posttranscriptional Gene Expression

O'Hara, S. P., Mott, J. L., Splinter, P. L., Gores, G. J. & La Russo, N. F., Jan 2009, In : Gastroenterology. 136, 1, p. 17-25 9 p.

Research output: Contribution to journalArticle

Gastrointestinal Neoplasms
Gene Expression Regulation
MicroRNAs
Cell Differentiation
Cell Cycle
10 Citations (Scopus)

MicroRNAs and benign biliary tract diseases

Gradilone, S. A., O'Hara, S. P., Masyuk, T. V., Pisarello, M. J. L. & La Russo, N. F., Feb 1 2015, In : Seminars in Liver Disease. 35, 1, p. 26-35 10 p.

Research output: Contribution to journalArticle

Biliary Tract Diseases
MicroRNAs
Biliary Tract
Small Untranslated RNA
Bile
17 Citations (Scopus)

MicroRNAs in cholangiociliopathies

Masyuk, T., Masyuk, A. & La Russo, N. F., May 1 2009, In : Cell Cycle. 8, 9, p. 1324-1328 5 p.

Research output: Contribution to journalArticle

MicroRNAs
Cell Cycle
Fluids and Secretions
Calcium Signaling
Liver
21 Citations (Scopus)

Microtubule modulation of biliary excretion of endogenous and exogenous hepatic lysosomal constituents.

Sewell, R. B., Barham, S. S., Zinsmeister, A. R. & La Russo, N. F., Jan 1984, In : The American journal of physiology. 246, 1 Pt 1

Research output: Contribution to journalArticle

Colchicine
Microtubules
Lysosomes
Vinblastine
Hepatocytes
11 Citations (Scopus)

Milder disease stage in patients with primary biliary cholangitis over a 44-year period: A changing natural history

on behalf of the GLOBAL PBC Study Group, May 1 2018, In : Hepatology. 67, 5, p. 1920-1930 11 p.

Research output: Contribution to journalArticle

Cholangitis
Natural History
Ursodeoxycholic Acid
Paris
Gastroenterology
26 Citations (Scopus)

Modified culture conditions enhance expression of differentiated phenotypic properties of normal rat cholangiocytes

Salter, K. D., Roman, R. M., La Russo, N. F., Fitz, J. G. & Doctor, R. B., 2000, In : Laboratory Investigation. 80, 11, p. 1775-1778 4 p.

Research output: Contribution to journalArticle

Bile Ducts
Culture Media
Cell Differentiation
Phenotype
Cell Line
116 Citations (Scopus)

Molecular and functional heterogeneity of cholangiocytes from rat liver after bile duct ligation

Alpini, G., Ulrich, C., Roberts, S., Phillips, J. O., Ueno, Y., Podila, P. V., Colegio, O., LeSage, G. D., Miller, L. J. & La Russo, N. F., Feb 1997, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 272, 2 35-2

Research output: Contribution to journalArticle

Bile Ducts
Ligation
Cystic Fibrosis Transmembrane Conductance Regulator
Liver
Biliary Tract
42 Citations (Scopus)

Molecular studies of ceruloplasmin deficiency in Wilson's disease

Czaja, M. J., Weiner, F. R., Schwarzenberg, S. J., Sternlieb, I., Scheinberg, I. H., Van Thiel, D. H., La Russo, N. F., Giambrone, M. A., Kirschner, R., Koschinsky, M. L., MacGillivray, R. T. A. & Zern, M. A., 1987, In : Journal of Clinical Investigation. 80, 4, p. 1200-1204 5 p.

Research output: Contribution to journalArticle

Hepatolenticular Degeneration
Ceruloplasmin
Messenger RNA
Serum
Familial apoceruloplasmin deficiency
100 Citations (Scopus)

Monooctanoin, a dissolution agent for retained cholesterol bile duct stones: Physical properties and clinical application

Thistle, J. L., Carlson, G. L., Hofmann, A. F., La Russo, N. F., MacCarty, R. L., Flynn, G. L., Higuchi, W. I. & Babayan, V. K., 1980, In : Gastroenterology. 78, 5 PART 1, p. 1016-1022 7 p.

Research output: Contribution to journalArticle

Bile Ducts
Cholesterol
Emulsifying Agents
Sodium Cholate
Biliary Tract
180 Citations (Scopus)

Morphological, molecular, and functional heterogeneity of cholangiocytes from normal rat liver

Alpini, G., Roberts, S., Kuntz, S. M., Ueno, Y., Gubba, S., Podila, P. V., LeSage, G. & La Russo, N. F., 1996, In : Gastroenterology. 110, 5, p. 1636-1643 8 p.

Research output: Contribution to journalArticle

Biliary Tract
Bile Ducts
Chloride-Bicarbonate Antiporters
Secretin
Liver
35 Citations (Scopus)

Morphologic demonstration of receptor-mediated endocytosis of epidermal growth factor by isolated bile duct epithelial cells

Ishii, M., Vroman, B. & La Russo, N. F., 1990, In : Gastroenterology. 98, 5 PART 1, p. 1284-1291 8 p.

Research output: Contribution to journalArticle

Endocytosis
Bile Ducts
Epidermal Growth Factor
Epithelial Cells
Gold Colloid
273 Citations (Scopus)

Morphologic features of chronic hepatitis associated with primary sclerosing cholangitis and chronic ulcerative colitis

Ludwig, J., Barham, S. S., La Russo, N. F., Elveback, L. R., Wiesner, R. H. & McCall, J. T., 1981, In : Hepatology. 1, 6, p. 632-640 9 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Chronic Hepatitis
Ulcerative Colitis
Bile Ducts
Copper
16 Citations (Scopus)

Morphology, physiology, and biochemistry of biliary epithelia

La Russo, N. F., Jan 1996, In : Toxicologic Pathology. 24, 1, p. 84-89 6 p.

Research output: Contribution to journalArticle

Biochemistry
Physiology
Pathology
Epithelium
147 Citations (Scopus)

Multiple TLRs are expressed in human cholangiocytes and mediate host epithelial defense responses to Cryptosporidium parvum via activation of NF-κB

Chen, X. M., O'Hara, S. P., Nelson, J. B., Splinter, P. L., Small, A. J., Tietz, P. S., Limper, A. H. & La Russo, N. F., Dec 1 2005, In : Journal of Immunology. 175, 11, p. 7447-7456 10 p.

Research output: Contribution to journalArticle

Cryptosporidium parvum
Defensins
Infection
Parasites
Proteins
280 Citations (Scopus)

Neutrophil cytoplasmic antibodies: A link between primary sclerosing cholangitis and ulcerative colitis

Duerr, R. H., Targan, S. R., Landers, C. J., La Russo, N. F., Lindsay, K. L., Wiesner, R. H. & Shanahan, F., 1991, In : Gastroenterology. 100, 5 PART 1, p. 1385-1391 7 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Ulcerative Colitis
Neutrophils
Antibodies
Serum
82 Citations (Scopus)

NFκB p50-CCAAT/enhancer-binding protein β (C/EBPβ)-mediated transcriptional repression of microRNA let-7i following microbial infection

O'Hara, S. P., Splinter, P. L., Gajdos, G. B., Trussoni, C. E., Fernandez-Zapico, M. E., Chen, X. M. & La Russo, N. F., Jan 1 2010, In : Journal of Biological Chemistry. 285, 1, p. 216-225 10 p.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Proteins
MicroRNAs
Infection
Cryptosporidium parvum
Toll-Like Receptor 4
231 Citations (Scopus)
Nitric Oxide
Carcinogenesis
Epithelial Cells
Inflammation
Neoplasms
150 Citations (Scopus)

Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes

Jaiswal, M., La Russo, N. F., Shapiro, R. A., Billiar, T. R. & Gores, G. J., 2001, In : Gastroenterology. 120, 1, p. 190-199 10 p.

Research output: Contribution to journalArticle

DNA Repair
DNA Damage
Nitric Oxide
Nitric Oxide Synthase Type II
Biliary Tract Diseases
81 Citations (Scopus)

Nonoperative dilatation of dominant strictures in primary sclerosing cholangitis

May, G. R., Bender, C. E., La Russo, N. F. & Wiesner, R. H., 1985, In : American Journal of Roentgenology. 145, 5, p. 1061-1064 4 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Dilatation
Pathologic Constriction
Cholangitis
Jaundice
190 Citations (Scopus)
Octreotide
Polycystic Kidney Diseases
Adenosine
Rodentia
Autosomal Recessive Polycystic Kidney
42 Citations (Scopus)

Opisthorchis viverrini excretory/secretory products induce toll-like receptor 4 upregulation and production of interleukin 6 and 8 in cholangiocyte

Ninlawan, K., O'Hara, S. P., Splinter, P. L., Yongvanit, P., Kaewkes, S., Surapaitoon, A., La Russo, N. F. & Sripa, B., Dec 2010, In : Parasitology International. 59, 4, p. 616-621 6 p.

Research output: Contribution to journalArticle

Opisthorchis
Toll-Like Receptor 4
Interleukin-8
Interleukin-6
Up-Regulation
13 Citations (Scopus)

Optimization of a research web environment for academic internal medicine faculty

Elkin, P. L., Sorensen, B., De Palo, D., Poland, G., Bailey, K. R., Wood, D. L. & La Russo, N. F., Sep 2002, In : Journal of the American Medical Informatics Association. 9, 5, p. 472-478 7 p.

Research output: Contribution to journalArticle

Internal Medicine
Research
Research Personnel
Informatics
Human Engineering
114 Citations (Scopus)

Oral budesonide in the treatment of primary sclerosing cholangitis

Angulo, P., Batts, K. P., Jorgensen, R. A., La Russo, N. F. & Lindor, K. D., 2000, In : American Journal of Gastroenterology. 95, 9, p. 2333-2337 5 p.

Research output: Contribution to journalArticle

Budesonide
Sclerosing Cholangitis
Therapeutics
Femur Neck
Gastroenterology
59 Citations (Scopus)

Oral nicotine in treatment of primary sclerosing cholangitis. A pilot study

Angulo, P., Bharucha, A. E., Jorgensen, R. A., DeSotel, C. K., Sandborn, W. J., La Russo, N. F. & Lindor, K. D., 1999, In : Digestive Diseases and Sciences. 44, 3, p. 602-607 6 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Nicotine
Cotinine
Therapeutics
Biochemistry
58 Citations (Scopus)

Pasireotide is more effective than octreotide in reducing hepatorenal cystogenesis in rodents with polycystic kidney and liver diseases

Masyuk, T. V., Radtke, B. N., Stroope, A. J., Banales, J. M., Gradilone, S. A., Huang, B., Masyuk, A. I., Hogan, M. C., Torres, V. & La Russo, N. F., Jul 2013, In : Hepatology. 58, 1, p. 409-421 13 p.

Research output: Contribution to journalArticle

Polycystic Kidney Diseases
Octreotide
Somatostatin Receptors
Rodentia
Cyclic AMP

Passing the torch: A look back at our editorship

La Russo, N. F., Phillips, S. F., Bloomer, J. R., Boland, C. R., Chang, E. B., DiMagno, E. P., Giannella, R. A., Gores, G. J., Malagelada, J. R., Miller, L. J., Rakela, J., Szurszewski, J. H., Binder, H. J., Clain, J. E., LaMont, J. T. & Link, A. M., 1996, In : Gastroenterology. 110, 5, p. 1336-1338 3 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Pathobiology of biliary epithelia

Roberts, S. K. & La Russo, N. F., 1994, In : Current Opinion in Gastroenterology. 10, 5, p. 526-533 8 p.

Research output: Contribution to journalArticle

Bile
Liver Diseases
Theoretical Models
Epithelium
Hormones
9 Citations (Scopus)

Pathobiology of biliary epithelia

Cheung, A. C., Lorenzo Pisarello, M. J. & La Russo, N. F., 2017, (Accepted/In press) In : Biochimica et Biophysica Acta - Molecular Basis of Disease.

Research output: Contribution to journalArticle

Biliary Tract
Cell Cycle Checkpoints
Bile Acids and Salts
Neurotransmitter Agents
Disease Progression
25 Citations (Scopus)

Pathobiology of biliary epithelia and cholangiocarcinoma: Proceedings of the Henry M. and Lillian Stratton Basic Research Single-Topic Conference

Sirica, A. E., Nathanson, M. H., Gores, G. J. & La Russo, N. F., 2008, In : Hepatology. 48, 6, p. 2040-2046 7 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Posters
Epithelium
Research
Critical Pathways
1 Citation (Scopus)

Patients, cells, and organelles: The intersection of science and serendipity

La Russo, N. F., May 2011, In : Hepatology. 53, 5, p. 1417-1426 10 p.

Research output: Contribution to journalArticle

21st Century History
20th Century History
Gastroenterology
Organelles
Biomedical Research
114 Citations (Scopus)

Patients with asymptomatic primary sclerosing cholangitis frequently have progressive disease

Porayko, M. K., Wiesner, R. H., La Russo, N. F., Ludwig, J., MacCarty, R. L., Steiner, B. L., Twomey, C. K. & Zinsmeister, A. R., 1990, In : Gastroenterology. 98, 6, p. 1594-1602 9 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Disease Progression
Cholangiography
Liver
Liver Failure
14 Citations (Scopus)

Perceived impact of duty hours limits on the fragmentation of patient care: Results from an academic health center

Keating, R. J., La Russo, N. F. & Kolars, J. C., Jul 2005, In : American Journal of Medicine. 118, 7, p. 788-793 6 p.

Research output: Contribution to journalArticle

Personnel Staffing and Scheduling
Physicians' Practice Patterns
Physician-Patient Relations
Job Satisfaction
Quality of Health Care
29 Citations (Scopus)

Performance of magnetic resonance elastography in primary sclerosing cholangitis

Eaton, J. E., Dzyubak, B., Venkatesh, S. K., Smyrk, T. C., Gores, G. J., Ehman, R. L., La Russo, N. F., Gossard, A. A. & Lazaridis, K. N., Jun 1 2016, In : Journal of Gastroenterology and Hepatology (Australia). 31, 6, p. 1184-1190 7 p.

Research output: Contribution to journalArticle

Elasticity Imaging Techniques
Sclerosing Cholangitis
Liver
Fibrosis
Alkaline Phosphatase
40 Citations (Scopus)

Perfused rat intrahepatic bile ducts secrete and absorb water, solute, and ions

Masyuk, A. I., Gong, A. Y., Kip, S., Burke, M. J. & La Russo, N. F., 2000, In : Gastroenterology. 119, 6, p. 1672-1680 9 p.

Research output: Contribution to journalArticle

Intrahepatic Bile Ducts
Ions
Taurocholic Acid
Water
Bile Acids and Salts
98 Citations (Scopus)

Peristomal varices after proctocolectomy in patients with primary sclerosing cholangitis

Wiesner, R. H., La Russo, N. F., Dozois, R. R. & Beaver, S. J., 1986, In : Gastroenterology. 90, 2, p. 316-322 7 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Varicose Veins
Ileostomy
Ulcerative Colitis
Hemorrhage
20 Citations (Scopus)

Pharmacologic perturbation of rat liver lysosomes: Effects on release of lysosomal enzymes and of lipids into bile

Sewell, R. B., Grinpukel, S. A., Zinsmeister, A. R. & La Russo, N. F., 1988, In : Gastroenterology. 95, 4, p. 1088-1098 11 p.

Research output: Contribution to journalArticle

Chloroquine
Lysosomes
Glucagon
Bile
Autophagy
38 Citations (Scopus)

Phosphatidylinositol 3-kinase and frabin mediate Cryptosporidium parvum cellular invasion via activation of Cdc42

Chen, X. M., Splinter, P. L., Tietz, P. S., Huang, B. Q., Billadeau, D. D. & La Russo, N. F., Jul 23 2004, In : Journal of Biological Chemistry. 279, 30, p. 31671-31678 8 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Cryptosporidium parvum
Chemical activation
Parasites
Actins
27 Citations (Scopus)

Physicochemical determinants in hepatic extraction of small peptides

Hunter, E. B., Powers, S. P., Kost, L. J., Pinon, D. I., Miller, L. J. & La Russo, N. F., Jul 1990, In : Hepatology. 12, 1, p. 76-82 7 p.

Research output: Contribution to journalArticle

Peptides
Liver
Hydrophobic and Hydrophilic Interactions
Cholecystokinin
Amino Acid Sequence
78 Citations (Scopus)

Physiology of cholangiocytes

Tabibian, J. H., Masyuk, A. I., Masyuk, T. V., O'Hara, S. P. & La Russo, N. F., 2013, In : Comprehensive Physiology. 3, 1, p. 541-565 25 p.

Research output: Contribution to journalArticle

Bile
Peptide Hormones
Biliary Tract
Neurotransmitter Agents
Hepatocytes
49 Citations (Scopus)

Pirfenidone in the treatment of primary sclerosing cholangitis

Angulo, P., MacCarty, R. L., Sylvestre, P. B., Jorgensen, R. A., Wiesner, R. H., La Russo, N. F. & Lindor, K. D., 2002, In : Digestive Diseases and Sciences. 47, 1, p. 157-161 5 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Biochemistry
Liver
Therapeutics
Cholangiography
5 Citations (Scopus)

Plasmaperfusion and studies of copper metabolism in benign recurrent cholestasis. Novel procedures in a rare syndrome

La Russo, N. F., Dickson, E. R. & Pineda, A. A., 1980, In : Mayo Clinic Proceedings. 55, 7, p. 450-454 5 p.

Research output: Contribution to journalArticle

Cholestasis
Pruritus
Copper
Jaundice
Therapeutics
83 Citations (Scopus)

Polarized expression and function of P2Y ATP receptors in rat bile duct epithelia

Dranoff, J. A., Masyuk, A. I., Kruglov, E. A., La Russo, N. F. & Nathanson, M. H., 2001, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 281, 4 44-4

Research output: Contribution to journalArticle

Purinergic P2 Receptors
Bile Ducts
Bile
Intrahepatic Bile Ducts
Epithelium
30 Citations (Scopus)

Polycystic liver disease: New insights into disease pathogenesis

Masyuk, T. & La Russo, N. F., May 2006, In : Hepatology. 43, 5, p. 906-908 3 p.

Research output: Contribution to journalArticle

Cysts
Liver Diseases
Polycystic liver disease

Polycystic liver disease: The interplay of genes causative for hepatic and renal cystogenesis

Masyuk, T. V., Masyuk, A. I. & La Russo, N. F., Jun 1 2018, In : Hepatology. 67, 6, p. 2462-2464 3 p.

Research output: Contribution to journalArticle

Kidney
Liver
Genes
Polycystic liver disease
32 Citations (Scopus)

Polycystic liver diseases: Advanced insights into the molecular mechanisms

Perugorria, M. J., Masyuk, T. V., Marin, J. J., Marzioni, M., Bujanda, L., La Russo, N. F. & Banales, J. M., Dec 11 2014, In : Nature Reviews Gastroenterology and Hepatology. 11, 12, p. 750-761 12 p.

Research output: Contribution to journalArticle

Cysts
Choledochal Cyst
Inborn Genetic Diseases
Liver
Therapeutics
29 Citations (Scopus)

Polymicrobial cholangitis and kaposi's sarcoma in blood product transfusion-related acquired immune deficiency syndrome

Cockerill, F. R., Hurley, D. V., Malagelada, J. R., La Russo, N. F., Edson, R. S., Katzmann, J. A., Banks, P. M., Wiltsie, J. C., Davis, J. P., Lack, E. E., Ishak, K. G. & Van Scoy, R. E., 1986, In : The American journal of medicine. 80, 6, p. 1237-1241 5 p.

Research output: Contribution to journalArticle

Cholangitis
Kaposi's Sarcoma
Blood Transfusion
Acquired Immunodeficiency Syndrome
Mycobacterium avium-intracellulare Infection
12 Citations (Scopus)
Microsatellite Instability
Tumor Suppressor Genes
Carcinogenesis
393 Citations (Scopus)

Pouchitis after ileal pouch-anal anastomosis for ulcerative colitis occurs with increased frequency in patients with associated primary sclerosing cholangitis

Penna, C., Dozois, R., Tremaine, W., Sandborn, W., La Russo, N. F., Schleck, C. & Ilstrup, D., 1996, In : Gut. 38, 2, p. 234-239 6 p.

Research output: Contribution to journalArticle

Pouchitis
Colonic Pouches
Sclerosing Cholangitis
Ulcerative Colitis
Liver Diseases
2 Citations (Scopus)

Primär sklerosierende Cholangitis.

Translated title of the contribution: Primary sclerosing cholangitisLa Russo, N. F. & Ludwig, J., Aug 15 1986, In : Deutsche Medizinische Wochenschrift. 111, 33, p. 1263 1 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangitis
Sclerosis
275 Citations (Scopus)

Primary sclerosing cholangitis: Findings on cholangiography and pancreatography

MacCarty, R. L., La Russo, N. F., Wiesner, R. H. & Ludwig, J., 1983, In : Radiology. 149, 1, p. 39-44 6 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangiography
Pathologic Constriction
Diverticulum
Bile Ducts