• 27361 Citations
  • 94 Scopus h-Index
1973 …2020

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Article

Hormones and microtubular binding agents selectively alter biliary lysosomal protein excretion

Sewell, R. B., Kost, L. J., Carter, J. A. & La Russo, N. F., 1981, In : Gastroenterology. 80, 5 II, p. 1281 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Host cell actin remodeling in response to Cryptosporidium.

O'Hara, S. P., Small, A. J., Chen, X. M. & La Russo, N. F., 2008, In : Sub-Cellular Biochemistry. 47, p. 92-100 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Human cholangiocarcinomas express somatostatin receptors and respond to somatostatin with growth inhibition

Chee Kiat Tan, K. T., Podila, P. V., Taylor, J. E., Nagorney, D. M., Wiseman, G. A., Gores, G. J. & La Russo, N. F., 1995, In : Gastroenterology. 108, 6, p. 1908-1916 9 p.

Research output: Contribution to journalArticle

46 Scopus citations

Human intestinal and biliary cryptosporidiosis

Chen, X. M. & La Russo, N. F., Oct 1999, In : World Journal of Gastroenterology. 5, 5, p. 424-429 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Human Ogg1, a protein involved in the repair of 8-oxoguanine, is inhibited by nitric oxide

Jaiswal, M., La Russo, N. F., Nishioka, N., Nakabeppu, Y. & Gores, G. J., Aug 1 2001, In : Cancer Research. 61, 17, p. 6388-6393 6 p.

Research output: Contribution to journalArticle

154 Scopus citations

Idiopathic adulthood ductopenia. A cause of chronic cholestatic liver disease and biliary cirrhosis

Ludwig, J., Wiesner, R. H. & La Russo, N. F., 1988, In : Journal of Hepatology. 7, 2, p. 193-199 7 p.

Research output: Contribution to journalArticle

133 Scopus citations
25 Scopus citations

II. Effect of chenodeoxycholic acid treatment in gallstone subjects

Northfield, T. C., La Russo, N. F., Hofmann, A. F. & Thistle, J. L., 1975, In : Gut. 16, 1, p. 12-17 6 p.

Research output: Contribution to journalArticle

66 Scopus citations

Immortalized liver endothelial cells: A cell culture model for studies of motility and angiogenesis

Huebert, R. C., Jagavelu, K., Liebl, A. F., Huang, B. Q., Splinter, P. L., La Russo, N. F., Urrutia, R. A. & Shah, V., Dec 2010, In : Laboratory Investigation. 90, 12, p. 1770-1781 12 p.

Research output: Contribution to journalArticle

39 Scopus citations

Immunohistologic labeling as an indicator of liver allograft rejection

Perkins, J. D., Wiesner, R. H., Banks, P. M., La Russo, N. F., Ludwig, J. & Krom, R. A., 1987, In : Transplantation. 43, 1, p. 105-108 4 p.

Research output: Contribution to journalArticle

24 Scopus citations

Immunohistologic labeling of infiltrating T lymphocytes in hepatic allografts: a rejection indicator.

Perkins, J. D., Wiesner, R. H., Banks, P. M., La Russo, N. F. & Krom, R. A., Feb 1987, In : Transplantation Proceedings. 19, 1 Pt 3, p. 2474-2475 2 p.

Research output: Contribution to journalArticle

6 Scopus citations

Improving attendance at medical grand rounds (multiple letters)

Kuo, D., Klainer, A. S., Reinharth, D., Dhatariya, K., Mueller, P., Litin, S. C., Sowden, M. L., Habermann, T. M. & La Russo, N. F., Jul 1 2003, In : Mayo Clinic Proceedings. 78, 7, p. 922-923 2 p.

Research output: Contribution to journalArticle

6 Scopus citations

Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism

Jaiswal, M., La Russo, N. F., Burgart, L. J. & Gores, G. J., Jan 1 2000, In : Cancer Research. 60, 1, p. 184-190 7 p.

Research output: Contribution to journalArticle

499 Scopus citations

Inhibition of Cdc25A suppresses hepato-renal cystogenesis in rodent models of polycystic kidney and liver disease

Masyuk, T. V., Radtke, B. N., Stroope, A. J., Banales, J. M., Masyuk, A. I., Gradilone, S. A., Gajdos, G. B., Chandok, N., Bakeberg, J. L., Ward, C. J., Ritman, E. L., Kiyokawa, H. & La Russo, N. F., Mar 2012, In : Gastroenterology. 142, 3, p. 622-633 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

Inhibition of cholesterol crystal formation by apolipoproteins in supersaturated model bile

Kibe, A., Holzbach, R. T., La Russo, N. F. & Mao, S. J. T., 1984, In : Science. 225, 4661, p. 514-516 3 p.

Research output: Contribution to journalArticle

160 Scopus citations

Inhibition of metalloprotease hyperactivity in cystic cholangiocytes halts the development of polycystic liver diseases.

Urribarri, A. D., Munoz-Garrido, P., Perugorria, M. J., Erice, O., Merino-Azpitarte, M., Arbelaiz, A., Lozano, E., Hijona, E., Jiménez-Agüero, R., Fernandez-Barrena, M. G., Jimeno, J. P., Marzioni, M., Marin, J. J. G., Masyuk, T. V., La Russo, N. F., Prieto, J., Bujanda, L. & Banales, J. M., 2014, In : Gut. 63, 10, p. 1658-1667 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

In primary sclerosing cholangitis, gallbladder polyps are frequently malignant

Buckles, D. C., Lindor, K. D., La Russo, N. F., Petrovic, L. M. & Gores, G. J., 2002, In : American Journal of Gastroenterology. 97, 5, p. 1138-1142 5 p.

Research output: Contribution to journalArticle

132 Scopus citations

Insignificant effect of secretin in rodent models of polycystic kidney and liver disease

Wang, X., Ye, H., Ward, C. J., Chu, J. Y. S., Masyuk, T. V., La Russo, N. F., Harris, P. C., Chow, B. K. C. & Torres, V., Oct 1 2012, In : American Journal of Physiology - Renal Physiology. 303, 7

Research output: Contribution to journalArticle

9 Scopus citations

Interaction of metronidazole with nucleic acids in vitro

La Russo, N. F., Tomasz, M., Muller, M. & Lipman, R., 1977, In : Molecular Pharmacology. 13, 5, p. 872-882 11 p.

Research output: Contribution to journalArticle

94 Scopus citations

Interactions between chronic liver disease and inflammatory bowel disease

Loftus, Jr, E. V., Sandborn, W. J., Lindor, K. D. & La Russo, N. F., Dec 1997, In : Inflammatory Bowel Diseases. 3, 4, p. 288-302 15 p.

Research output: Contribution to journalArticle

52 Scopus citations

Intrahepatic bile ducts transport water in response to absorbed glucose

Masyuk, A. I., Masyuk, T. V., Tietz, P. S., Splinter, P. L. & La Russo, N. F., Sep 2002, In : American Journal of Physiology - Cell Physiology. 283, 3 52-3

Research output: Contribution to journalArticle

35 Scopus citations

Intrahepatic cholangiectases and large-duct obliteration in primary sclerosing cholangitis

Ludwig, J., MacCarty, R. L., La Russo, N. F., Krom, R. A. & Wiesner, R. H., 1986, In : Hepatology. 6, 4, p. 560-568 9 p.

Research output: Contribution to journalArticle

57 Scopus citations

Isolation and characterization of cholangiocyte primary cilia

Huang, B. Q., Masyuk, T. V., Muff, M. A., Tietz, P. S., Masyuk, A. I. & La Russo, N. F., 2006, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 291, 3

Research output: Contribution to journalArticle

62 Scopus citations

Isolation and characterization of lipid microdomains from apical and basolateral plasma membranes of rat hepatocytes

Mazzone, A., Tietz, P., Jefferson, J., Pagano, R. & La Russo, N. F., Feb 2006, In : Hepatology. 43, 2, p. 287-296 10 p.

Research output: Contribution to journalArticle

62 Scopus citations

Isolation and characterization of rat cholangiocyte vesicles enriched in apical or basolateral plasma membrane domains

Tietz, P. S., Holman, R. T., Miller, L. J. & La Russo, N. F., 1995, In : Biochemistry. 34, 47, p. 15436-15443 8 p.

Research output: Contribution to journalArticle

54 Scopus citations

Isolation and morphologic characterization of bile duct epithelial cells from normal rat liver

Ishii, M., Vroman, B. & La Russo, N. F., 1989, In : Gastroenterology. 97, 5, p. 1236-1247 12 p.

Research output: Contribution to journalArticle

177 Scopus citations

Isolation of primary cilia for morphological analysis.

Huang, B., Masyuk, T. & La Russo, N. F., 2009, In : Methods in Cell Biology. 94, p. 103-115 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Isolation of the microtubule-vesicle motor kinesin from rat liver: Selective inhibition by cholestatic bile acids

Marks, D. L., La Russo, N. F. & Mc Niven, M. A., 1995, In : Gastroenterology. 108, 3, p. 824-833 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Is primary sclerosing cholangitis a bad disease?

La Russo, N. F., Wiesner, R. H. & Ludwig, J., 1987, In : Gastroenterology. 92, 6, p. 2031-2033 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Is primary sclerosing cholangitis a progressive disease or not?

Wiesner, R. H., Grambsch, P., La Russo, N. F. & Dickson, E. R., Jul 1988, In : Hepatology. 8, 4, p. 970-972 3 p.

Research output: Contribution to journalArticle

17 Scopus citations
53 Scopus citations

Lack of metabolic effects of cholecystokinin on hepatocytes

Kost, L. J., Gores, G. J., Sayles, J. M., Miller, L. J., Lemasters, J. J., Herman, B. & La Russo, N. F., Aug 1990, In : Hepatology. 12, 2, p. 301-305 5 p.

Research output: Contribution to journalArticle

12 Scopus citations
93 Scopus citations

Liver transplantation for primary sclerosing cholangitis: Impact of risk factors on outcome

Wiesner, R. H., Porayko, M. K., Hay, J. E., La Russo, N. F., Steers, J. L., Krom, R. A. F. & Dickson, E. R., 1996, In : Liver Transplantation and Surgery. 2, 5 SUPPL. 1, p. 99-108 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Localized glucose and water influx facilitates Cryptosporidium parvum cellular invasion by means of modulation of host-cell membrane protrusion

Chen, X. M., O'Hara, S. P., Huang, B. Q., Splinter, P. L., Nelson, J. B. & La Russo, N. F., May 3 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 18, p. 6338-6343 6 p.

Research output: Contribution to journalArticle

69 Scopus citations

Long-term results of patients undergoing liver transplantation for primary sclerosing cholangitis

Graziadei, I. W., Wiesner, R. H., Marotta, P. J., Porayko, M. K., Eileen Hay, J., Charlton, M. R., Poterucha, J. J., Rosen, C. B., Gores, G. J., La Russo, N. F. & Krom, R. A. F., 1999, In : Hepatology. 30, 5, p. 1121-1127 7 p.

Research output: Contribution to journalArticle

269 Scopus citations

Lymphocyte subsets in primary sclerosing cholangitis

Lindor, K. D., Wiesner, R. H., Katzmann, J. A., La Russo, N. F. & Beaver, S. J., Jul 1987, In : Digestive Diseases and Sciences. 32, 7, p. 720-725 6 p.

Research output: Contribution to journalArticle

54 Scopus citations

Lysosomal enzymes in biological fluids. Physiologic and pathophysiologic significance

La Russo, N. F., 1979, In : Digestive Diseases and Sciences. 24, 3, p. 177-179 3 p.

Research output: Contribution to journalArticle

10 Scopus citations

Macrophages contribute to the pathogenesis of sclerosing cholangitis in mice

Guicciardi, M. E., Trussoni, C. E., Krishnan, A., Bronk, S. F., Lorenzo Pisarello, M. J., O'Hara, S. P., Splinter, P. L., Gao, Y., Vig, P., Revzin, A., La Russo, N. F. & Gores, G. J., Jan 1 2018, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

19 Scopus citations

Magnetic resonance cholangiography in patients with biliary disease: Its role in primary sclerosing cholangitis

Angulo, P., Pearce, D. H., Johnson, C. D., Henry, J. J., La Russo, N. F., Petersen, B. T. & Lindor, K. D., 2000, In : Journal of Hepatology. 33, 4, p. 520-527 8 p.

Research output: Contribution to journalArticle

132 Scopus citations

Manifestations of nonsuppurative cholangitis in chronic hepatobiliary diseases: Morphologic spectrum, clinical correlations and terminology

Ludwig, J., Czaja, A. J., Dickson, E. R., La Russo, N. F. & Wiesner, R. H., 1984, In : Liver. 4, 2, p. 105-116 12 p.

Research output: Contribution to journalArticle

103 Scopus citations

Medical progress: Biliary tract cancers

De Groen, P. C., Gores, G. J., La Russo, N. F., Gunderson, L. L. & Nagorney, D. M., Oct 28 1999, In : New England Journal of Medicine. 341, 18, p. 1368-1378 11 p.

Research output: Contribution to journalArticle

789 Scopus citations

Membrane microdomains in hepatocytes: Potential target areas for proteins involved in canalicular bile secretion

Tietz, P., Jefferson, J., Pagano, R. & La Russo, N. F., 2005, In : Journal of Lipid Research. 46, 7, p. 1426-1432 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Metabolomic profiling of portal blood and bile reveals metabolic signatures of primary sclerosing cholangitis

Tietz-Bogert, P. S., Kim, M., Cheung, A., Tabibian, J. H., Heimbach, J. K., Rosen, C. B., Nandakumar, M., Lazaridis, K. N., La Russo, N. F., Sung, J. & O’hara, S. P., Oct 16 2018, In : International Journal of Molecular Sciences. 19, 10, 3188.

Research output: Contribution to journalArticle

4 Scopus citations

Microbiome-immune interactions and liver disease

Tabibian, J. H., Varghese, C., O'Hara, S. P. & La Russo, N. F., Apr 1 2015, In : Clinical Liver Disease. 5, 4, p. 83-85 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Micro-computed tomography and nuclear magnetic resonance imaging for noninvasive, live-mouse cholangiography

Tabibian, J. H., Macura, S. I., O'Hara, S. P., Fidler, J. L., Glockner, J., Takahashi, N., Lowe, V., Kemp, B. J., Mishra, P. K., Tietz, P. S., Splinter, P. L., Trussoni, C. E. & La Russo, N. F., Jun 2013, In : Laboratory Investigation. 93, 6, p. 733-743 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

MicroRNA (miR)-433 and miR-22 dysregulations induce histone-deacetylase-6 overexpression and ciliary loss in cholangiocarcinoma

Mansini, A. P., Lorenzo Pisarello, M. J., Thelen, K. M., Cruz-Reyes, M., Peixoto, E., Jin, S., Howard, B. N., Trussoni, C. E., Gajdos, G. B., La Russo, N. F., Perugorria, M. J., Banales, J. M. & Gradilone, S. A., Aug 1 2018, In : Hepatology. 68, 2, p. 561-573 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

MicroRNA15a modulates expression of the cell-cycle regulator Cdc25A and affects hepatic cystogenesis in a rat model of polycystic kidney disease

Lee, S. O., Masyuk, T., Splinter, P., Banales, J. M., Masyuk, A., Stroope, A. & La Russo, N. F., Nov 3 2008, In : Journal of Clinical Investigation. 118, 11, p. 3714-3724 11 p.

Research output: Contribution to journalArticle

124 Scopus citations

MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3

Selaru, F. M., Olaru, A. V., Kan, T., David, S., Cheng, Y., Mori, Y., Yang, J., Paun, B., Jin, Z., Agarwal, R., Hamilton, J. P., Abraham, J., Georgiades, C., Alvarez, H., Vivekanandan, P., Yu, W., Maitra, A., Torbenson, M., Thuluvath, P. J., Gores, G. J. & 3 others, La Russo, N. F., Hruban, R. & Meltzer, S. J., May 2009, In : Hepatology. 49, 5, p. 1595-1601 7 p.

Research output: Contribution to journalArticle

208 Scopus citations

MicroRNA-506 promotes primary biliary cholangitis-like features in cholangiocytes and immune activation

Erice, O., Munoz-Garrido, P., Vaquero, J., Perugorria, M. J., Fernandez-Barrena, M. G., Saez, E., Santos-Laso, A., Arbelaiz, A., Jimenez-Agüero, R., Fernandez-Irigoyen, J., Santamaria, E., Torrano, V., Carracedo, A., Ananthanarayanan, M., Marzioni, M., Prieto, J., Beuers, U., Oude Elferink, R. P., La Russo, N. F., Bujanda, L. & 2 others, Marin, J. J. G. & Banales, J. M., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

19 Scopus citations