• 26904 Citations
  • 93 Scopus h-Index
1973 …2019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1973 2019

Filter
Article
9 Citations (Scopus)

Host cell actin remodeling in response to Cryptosporidium.

O'Hara, S. P., Small, A. J., Chen, X. M. & La Russo, N. F., 2008, In : Sub-Cellular Biochemistry. 47, p. 92-100 9 p.

Research output: Contribution to journalArticle

Cryptosporidium
Actins
Parasites
Host-Pathogen Interactions
Pathogens
46 Citations (Scopus)

Human cholangiocarcinomas express somatostatin receptors and respond to somatostatin with growth inhibition

Chee Kiat Tan, K. T., Podila, P. V., Taylor, J. E., Nagorney, D. M., Wiseman, G. A., Gores, G. J. & La Russo, N. F., 1995, In : Gastroenterology. 108, 6, p. 1908-1916 9 p.

Research output: Contribution to journalArticle

Somatostatin Receptors
Cholangiocarcinoma
Somatostatin
Growth
seglitide
6 Citations (Scopus)

Human intestinal and biliary cryptosporidiosis

Chen, X. M. & La Russo, N. F., Oct 1999, In : World Journal of Gastroenterology. 5, 5, p. 424-429 6 p.

Research output: Contribution to journalArticle

Cryptosporidium parvum
Cryptosporidiosis
152 Citations (Scopus)

Human Ogg1, a protein involved in the repair of 8-oxoguanine, is inhibited by nitric oxide

Jaiswal, M., La Russo, N. F., Nishioka, N., Nakabeppu, Y. & Gores, G. J., Aug 1 2001, In : Cancer Research. 61, 17, p. 6388-6393 6 p.

Research output: Contribution to journalArticle

DNA Repair
Nitric Oxide
Proteins
S-Nitrosothiols
Inflammation
133 Citations (Scopus)

Idiopathic adulthood ductopenia. A cause of chronic cholestatic liver disease and biliary cirrhosis

Ludwig, J., Wiesner, R. H. & La Russo, N. F., 1988, In : Journal of Hepatology. 7, 2, p. 193-199 7 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Liver Cirrhosis
Liver Diseases
Intrahepatic Bile Ducts
Inflammatory Bowel Diseases
24 Citations (Scopus)
Teaching Rounds
physician
Prospective Studies
food
Physicians
66 Citations (Scopus)

II. Effect of chenodeoxycholic acid treatment in gallstone subjects

Northfield, T. C., La Russo, N. F., Hofmann, A. F. & Thistle, J. L., 1975, In : Gut. 16, 1, p. 12-17 6 p.

Research output: Contribution to journalArticle

Chenodeoxycholic Acid
Gallstones
Bile Acids and Salts
Gallbladder
Cholesterol
37 Citations (Scopus)

Immortalized liver endothelial cells: A cell culture model for studies of motility and angiogenesis

Huebert, R. C., Jagavelu, K., Liebl, A. F., Huang, B. Q., Splinter, P. L., La Russo, N. F., Urrutia, R. A. & Shah, V., Dec 2010, In : Laboratory Investigation. 90, 12, p. 1770-1781 12 p.

Research output: Contribution to journalArticle

Endothelial Cells
Cell Culture Techniques
Liver
Pseudopodia
Endocytosis
24 Citations (Scopus)

Immunohistologic labeling as an indicator of liver allograft rejection

Perkins, J. D., Wiesner, R. H., Banks, P. M., La Russo, N. F., Ludwig, J. & Krom, R. A., 1987, In : Transplantation. 43, 1, p. 105-108 4 p.

Research output: Contribution to journalArticle

Helper-Inducer T-Lymphocytes
Allografts
Liver
Transplants
Cyclosporine
6 Citations (Scopus)

Immunohistologic labeling of infiltrating T lymphocytes in hepatic allografts: a rejection indicator.

Perkins, J. D., Wiesner, R. H., Banks, P. M., La Russo, N. F. & Krom, R. A., Feb 1987, In : Transplantation Proceedings. 19, 1 Pt 3, p. 2474-2475 2 p.

Research output: Contribution to journalArticle

Cyclosporins
Hepatic Artery
Homologous Transplantation
Cytomegalovirus Infections
Graft Rejection
6 Citations (Scopus)

Improving attendance at medical grand rounds (multiple letters)

Kuo, D., Klainer, A. S., Reinharth, D., Dhatariya, K., Mueller, P., Litin, S. C., Sowden, M. L., Habermann, T. M. & La Russo, N. F., Jul 1 2003, In : Mayo Clinic Proceedings. 78, 7, p. 922-923 2 p.

Research output: Contribution to journalArticle

492 Citations (Scopus)

Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism

Jaiswal, M., La Russo, N. F., Burgart, L. J. & Gores, G. J., Jan 1 2000, In : Cancer Research. 60, 1, p. 184-190 7 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
DNA Repair
DNA Damage
Nitric Oxide
Cytokines
25 Citations (Scopus)

Inhibition of Cdc25A suppresses hepato-renal cystogenesis in rodent models of polycystic kidney and liver disease

Masyuk, T. V., Radtke, B. N., Stroope, A. J., Banales, J. M., Masyuk, A. I., Gradilone, S. A., Gajdos, G. B., Chandok, N., Bakeberg, J. L., Ward, C. J., Ritman, E. L., Kiyokawa, H. & La Russo, N. F., Mar 2012, In : Gastroenterology. 142, 3, p. 622-633 12 p.

Research output: Contribution to journalArticle

Polycystic Kidney Diseases
Rodentia
Kidney
Cell Cycle
Vitamin K 3
160 Citations (Scopus)

Inhibition of cholesterol crystal formation by apolipoproteins in supersaturated model bile

Kibe, A., Holzbach, R. T., La Russo, N. F. & Mao, S. J. T., 1984, In : Science. 225, 4661, p. 514-516 3 p.

Research output: Contribution to journalArticle

Apolipoproteins
Bile
Cholesterol
Apolipoprotein A-I
varespladib methyl
21 Citations (Scopus)

Inhibition of metalloprotease hyperactivity in cystic cholangiocytes halts the development of polycystic liver diseases.

Urribarri, A. D., Munoz-Garrido, P., Perugorria, M. J., Erice, O., Merino-Azpitarte, M., Arbelaiz, A., Lozano, E., Hijona, E., Jiménez-Agüero, R., Fernandez-Barrena, M. G., Jimeno, J. P., Marzioni, M., Marin, J. J. G., Masyuk, T. V., La Russo, N. F., Prieto, J., Bujanda, L. & Banales, J. M., 2014, In : Gut. 63, 10, p. 1658-1667 10 p.

Research output: Contribution to journalArticle

Metalloproteases
Polycystic Kidney Diseases
Interleukin-6
Liver
Licensure
128 Citations (Scopus)

In primary sclerosing cholangitis, gallbladder polyps are frequently malignant

Buckles, D. C., Lindor, K. D., La Russo, N. F., Petrovic, L. M. & Gores, G. J., 2002, In : American Journal of Gastroenterology. 97, 5, p. 1138-1142 5 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Polyps
Gallbladder
Cholecystectomy
Gallbladder Neoplasms
9 Citations (Scopus)

Insignificant effect of secretin in rodent models of polycystic kidney and liver disease

Wang, X., Ye, H., Ward, C. J., Chu, J. Y. S., Masyuk, T. V., La Russo, N. F., Harris, P. C., Chow, B. K. C. & Torres, V., Oct 1 2012, In : American Journal of Physiology - Renal Physiology. 303, 7

Research output: Contribution to journalArticle

Polycystic Kidney Diseases
Secretin
Rodentia
Adenylyl Cyclases
Cyclic AMP
94 Citations (Scopus)

Interaction of metronidazole with nucleic acids in vitro

La Russo, N. F., Tomasz, M., Muller, M. & Lipman, R., 1977, In : Molecular Pharmacology. 13, 5, p. 872-882 11 p.

Research output: Contribution to journalArticle

Metronidazole
Nucleic Acids
Dithionite
Bacterial DNA
Cytosine
52 Citations (Scopus)

Interactions between chronic liver disease and inflammatory bowel disease

Loftus, Jr, E. V., Sandborn, W. J., Lindor, K. D. & La Russo, N. F., Dec 1997, In : Inflammatory Bowel Diseases. 3, 4, p. 288-302 15 p.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Liver Diseases
Chronic Disease
Inflammatory Bowel Disease 3
Inflammatory Bowel Disease 4
34 Citations (Scopus)

Intrahepatic bile ducts transport water in response to absorbed glucose

Masyuk, A. I., Masyuk, T. V., Tietz, P. S., Splinter, P. L. & La Russo, N. F., Sep 2002, In : American Journal of Physiology - Cell Physiology. 283, 3 52-3

Research output: Contribution to journalArticle

Intrahepatic Bile Ducts
Ducts
Glucose
Water
Bile
57 Citations (Scopus)

Intrahepatic cholangiectases and large-duct obliteration in primary sclerosing cholangitis

Ludwig, J., MacCarty, R. L., La Russo, N. F., Krom, R. A. & Wiesner, R. H., 1986, In : Hepatology. 6, 4, p. 560-568 9 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Bile Ducts
Cholangitis
Intrahepatic Bile Ducts
Superinfection
61 Citations (Scopus)

Isolation and characterization of cholangiocyte primary cilia

Huang, B. Q., Masyuk, T. V., Muff, M. A., Tietz, P. S., Masyuk, A. I. & La Russo, N. F., 2006, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 291, 3

Research output: Contribution to journalArticle

Cilia
Bile Ducts
Organelles
Far-Western Blotting
Liver
62 Citations (Scopus)

Isolation and characterization of lipid microdomains from apical and basolateral plasma membranes of rat hepatocytes

Mazzone, A., Tietz, P., Jefferson, J., Pagano, R. & La Russo, N. F., Feb 2006, In : Hepatology. 43, 2, p. 287-296 10 p.

Research output: Contribution to journalArticle

Hepatocytes
Cell Membrane
Lipids
Detergents
Caveolin 1
54 Citations (Scopus)

Isolation and characterization of rat cholangiocyte vesicles enriched in apical or basolateral plasma membrane domains

Tietz, P. S., Holman, R. T., Miller, L. J. & La Russo, N. F., 1995, In : Biochemistry. 34, 47, p. 15436-15443 8 p.

Research output: Contribution to journalArticle

Cell membranes
Rats
Cell Membrane
Transmission Electron Microscopy
Cystic Fibrosis Transmembrane Conductance Regulator
177 Citations (Scopus)

Isolation and morphologic characterization of bile duct epithelial cells from normal rat liver

Ishii, M., Vroman, B. & La Russo, N. F., 1989, In : Gastroenterology. 97, 5, p. 1236-1247 12 p.

Research output: Contribution to journalArticle

Intrahepatic Bile Ducts
Bile Ducts
Epithelial Cells
Liver
Isopycnic Centrifugation
6 Citations (Scopus)

Isolation of primary cilia for morphological analysis.

Huang, B., Masyuk, T. & La Russo, N. F., 2009, In : Methods in Cell Biology. 94, p. 103-115 13 p.

Research output: Contribution to journalArticle

Cilia
Cultured Cells
Epithelial Cells
Transmission Electron Microscopy
Confocal Microscopy
31 Citations (Scopus)

Isolation of the microtubule-vesicle motor kinesin from rat liver: Selective inhibition by cholestatic bile acids

Marks, D. L., La Russo, N. F. & Mc Niven, M. A., 1995, In : Gastroenterology. 108, 3, p. 824-833 10 p.

Research output: Contribution to journalArticle

Kinesin
Bile Acids and Salts
Microtubules
Liver
Adenosine Triphosphatases
6 Citations (Scopus)

Is primary sclerosing cholangitis a bad disease?

La Russo, N. F., Wiesner, R. H. & Ludwig, J., 1987, In : Gastroenterology. 92, 6, p. 2031-2033 3 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangitis
Sclerosis
17 Citations (Scopus)

Is primary sclerosing cholangitis a progressive disease or not?

Wiesner, R. H., Grambsch, P., La Russo, N. F. & Dickson, E. R., Jul 1988, In : Hepatology. 8, 4, p. 970-972 3 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangitis
Sclerosis
Natural History
Bilirubin
52 Citations (Scopus)
Sodium-Glucose Transport Proteins
Monosaccharides
Reverse Transcriptase Polymerase Chain Reaction
Glucose
Bile
12 Citations (Scopus)

Lack of metabolic effects of cholecystokinin on hepatocytes

Kost, L. J., Gores, G. J., Sayles, J. M., Miller, L. J., Lemasters, J. J., Herman, B. & La Russo, N. F., Aug 1990, In : Hepatology. 12, 2, p. 301-305 5 p.

Research output: Contribution to journalArticle

Cholecystokinin
Hepatocytes
Sincalide
Amino Acids
Liver
91 Citations (Scopus)
Tight Junctions
Lipopolysaccharides
Occludin
Genistein
Permeability
38 Citations (Scopus)

Liver transplantation for primary sclerosing cholangitis: Impact of risk factors on outcome

Wiesner, R. H., Porayko, M. K., Hay, J. E., La Russo, N. F., Steers, J. L., Krom, R. A. F. & Dickson, E. R., 1996, In : Liver Transplantation and Surgery. 2, 5 SUPPL. 1, p. 99-108 10 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Liver Transplantation
Theoretical Models
68 Citations (Scopus)

Localized glucose and water influx facilitates Cryptosporidium parvum cellular invasion by means of modulation of host-cell membrane protrusion

Chen, X. M., O'Hara, S. P., Huang, B. Q., Splinter, P. L., Nelson, J. B. & La Russo, N. F., May 3 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 18, p. 6338-6343 6 p.

Research output: Contribution to journalArticle

Cell Surface Extensions
Cryptosporidium parvum
Aquaporin 1
Actins
Glucose
266 Citations (Scopus)

Long-term results of patients undergoing liver transplantation for primary sclerosing cholangitis

Graziadei, I. W., Wiesner, R. H., Marotta, P. J., Porayko, M. K., Eileen Hay, J., Charlton, M. R., Poterucha, J. J., Rosen, C. B., Gores, G. J., La Russo, N. F. & Krom, R. A. F., 1999, In : Hepatology. 30, 5, p. 1121-1127 7 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Liver Transplantation
Graft Survival
Pathologic Constriction
Recurrence
54 Citations (Scopus)

Lymphocyte subsets in primary sclerosing cholangitis

Lindor, K. D., Wiesner, R. H., Katzmann, J. A., La Russo, N. F. & Beaver, S. J., Jul 1987, In : Digestive Diseases and Sciences. 32, 7, p. 720-725 6 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Lymphocyte Subsets
B-Lymphocytes
Obstructive Jaundice
gamma-Globulins
9 Citations (Scopus)

Lysosomal enzymes in biological fluids. Physiologic and pathophysiologic significance

La Russo, N. F., 1979, In : Digestive Diseases and Sciences. 24, 3, p. 177-179 3 p.

Research output: Contribution to journalArticle

Pancreatic Juice
Exocytosis
Body Fluids
Hydrolases
Lysosomes
13 Citations (Scopus)

Macrophages contribute to the pathogenesis of sclerosing cholangitis in mice

Guicciardi, M. E., Trussoni, C. E., Krishnan, A., Bronk, S. F., Lorenzo Pisarello, M. J., O'Hara, S. P., Splinter, P. L., Gao, Y., Vig, P., Revzin, A., La Russo, N. F. & Gores, G. J., Jan 1 2018, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Macrophages
Liver
Monocytes
Wounds and Injuries
132 Citations (Scopus)

Magnetic resonance cholangiography in patients with biliary disease: Its role in primary sclerosing cholangitis

Angulo, P., Pearce, D. H., Johnson, C. D., Henry, J. J., La Russo, N. F., Petersen, B. T. & Lindor, K. D., 2000, In : Journal of Hepatology. 33, 4, p. 520-527 8 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangiography
Magnetic Resonance Spectroscopy
Endoscopic Retrograde Cholangiopancreatography
Factor IX
103 Citations (Scopus)

Manifestations of nonsuppurative cholangitis in chronic hepatobiliary diseases: Morphologic spectrum, clinical correlations and terminology

Ludwig, J., Czaja, A. J., Dickson, E. R., La Russo, N. F. & Wiesner, R. H., 1984, In : Liver. 4, 2, p. 105-116 12 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangitis
Biliary Liver Cirrhosis
Sclerosis
Lymphoid Tissue
779 Citations (Scopus)

Medical progress: Biliary tract cancers

De Groen, P. C., Gores, G. J., La Russo, N. F., Gunderson, L. L. & Nagorney, D. M., Oct 28 1999, In : New England Journal of Medicine. 341, 18, p. 1368-1378 11 p.

Research output: Contribution to journalArticle

Biliary Tract Neoplasms
X Ray Computed Tomography
Cholangiography
Biliary Tract
46 Citations (Scopus)

Membrane microdomains in hepatocytes: Potential target areas for proteins involved in canalicular bile secretion

Tietz, P., Jefferson, J., Pagano, R. & La Russo, N. F., 2005, In : Journal of Lipid Research. 46, 7, p. 1426-1432 7 p.

Research output: Contribution to journalArticle

Membrane Microdomains
Sphingolipids
Bile
Hepatocytes
Membranes
2 Citations (Scopus)

Metabolomic profiling of portal blood and bile reveals metabolic signatures of primary sclerosing cholangitis

Tietz-Bogert, P. S., Kim, M., Cheung, A., Tabibian, J. H., Heimbach, J. K., Rosen, C. B., Nandakumar, M., Lazaridis, K. N., La Russo, N. F., Sung, J. & O’hara, S. P., Oct 16 2018, In : International Journal of Molecular Sciences. 19, 10, 3188.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Metabolomics
metabolites
Bile
serums
1 Citation (Scopus)

Microbiome-immune interactions and liver disease

Tabibian, J. H., Varghese, C., O'Hara, S. P. & La Russo, N. F., Apr 1 2015, In : Clinical Liver Disease. 5, 4, p. 83-85 3 p.

Research output: Contribution to journalArticle

Microbiota
Immune System Diseases
Liver Diseases
17 Citations (Scopus)

Micro-computed tomography and nuclear magnetic resonance imaging for noninvasive, live-mouse cholangiography

Tabibian, J. H., Macura, S. I., O'Hara, S. P., Fidler, J. L., Glockner, J., Takahashi, N., Lowe, V., Kemp, B. J., Mishra, P. K., Tietz, P. S., Splinter, P. L., Trussoni, C. E. & La Russo, N. F., Jun 2013, In : Laboratory Investigation. 93, 6, p. 733-743 11 p.

Research output: Contribution to journalArticle

Cholangiography
Magnetic Resonance Spectroscopy
Tomography
Magnetic Resonance Imaging
Sclerosing Cholangitis
7 Citations (Scopus)

MicroRNA (miR)-433 and miR-22 dysregulations induce histone-deacetylase-6 overexpression and ciliary loss in cholangiocarcinoma

Mansini, A. P., Lorenzo Pisarello, M. J., Thelen, K. M., Cruz-Reyes, M., Peixoto, E., Jin, S., Howard, B. N., Trussoni, C. E., Gajdos, G. B., La Russo, N. F., Perugorria, M. J., Banales, J. M. & Gradilone, S. A., Aug 1 2018, In : Hepatology. 68, 2, p. 561-573 13 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Cholangiocarcinoma
MicroRNAs
Karyopherins
Cilia
123 Citations (Scopus)

MicroRNA15a modulates expression of the cell-cycle regulator Cdc25A and affects hepatic cystogenesis in a rat model of polycystic kidney disease

Lee, S. O., Masyuk, T., Splinter, P., Banales, J. M., Masyuk, A., Stroope, A. & La Russo, N. F., Nov 3 2008, In : Journal of Clinical Investigation. 118, 11, p. 3714-3724 11 p.

Research output: Contribution to journalArticle

Polycystic Kidney Diseases
Cell Cycle
MicroRNAs
Liver
Cell Proliferation
206 Citations (Scopus)

MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3

Selaru, F. M., Olaru, A. V., Kan, T., David, S., Cheng, Y., Mori, Y., Yang, J., Paun, B., Jin, Z., Agarwal, R., Hamilton, J. P., Abraham, J., Georgiades, C., Alvarez, H., Vivekanandan, P., Yu, W., Maitra, A., Torbenson, M., Thuluvath, P. J., Gores, G. J. & 3 others, La Russo, N. F., Hruban, R. & Meltzer, S. J., May 2009, In : Hepatology. 49, 5, p. 1595-1601 7 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinase-3
Cholangiocarcinoma
MicroRNAs
Cell Death
Reverse Transcriptase Polymerase Chain Reaction
15 Citations (Scopus)

MicroRNA-506 promotes primary biliary cholangitis-like features in cholangiocytes and immune activation

Erice, O., Munoz-Garrido, P., Vaquero, J., Perugorria, M. J., Fernandez-Barrena, M. G., Saez, E., Santos-Laso, A., Arbelaiz, A., Jimenez-Agüero, R., Fernandez-Irigoyen, J., Santamaria, E., Torrano, V., Carracedo, A., Ananthanarayanan, M., Marzioni, M., Prieto, J., Beuers, U., Oude Elferink, R. P., La Russo, N. F., Bujanda, L. & 2 others, Marin, J. J. G. & Banales, J. M., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Cholangitis
MicroRNAs
Dihydrolipoyllysine-Residue Acetyltransferase
Chloride-Bicarbonate Antiporters
Cytokines
128 Citations (Scopus)

MicroRNA-513 regulates B7-H1 translation and is involved in IFN-γ-induced B7-H1 expression in cholangiocytes

Gong, A. Y., Zhou, R., Hu, G., Li, X., Splinter, P. L., O'Hara, S. P., La Russo, N. F., Soukup, G. A., Dong, H. M. & Chen, X. M., Feb 1 2009, In : Journal of Immunology. 182, 3, p. 1325-1333 9 p.

Research output: Contribution to journalArticle

MicroRNAs
3' Untranslated Regions
Transfection
Proteins
B7 Antigens