• 26904 Citations
  • 93 Scopus h-Index
1973 …2019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1973 2019

Filter
Article
41 Citations (Scopus)

Cryptosporidiosis and the pathogenesis of AIDS-cholangiopathy

Chen, X. M. & La Russo, N. F., Aug 2002, In : Seminars in Liver Disease. 22, 3, p. 277-289 13 p.

Research output: Contribution to journalArticle

Cryptosporidiosis
Acquired Immunodeficiency Syndrome
Cryptosporidium
Biliary Tract
Epithelium
93 Citations (Scopus)

Cryptosporidium parvum activates nuclear factor κB in biliary epithelia preventing epithelial cell apoptosis

Chen, X. M., Levine, S. A., Splinter, P. L., Tietz, P. S., Ganong, A. L., Jobin, C., Gores, G. J., Paya, C. V. & La Russo, N. F., 2001, In : Gastroenterology. 120, 7, p. 1774-1783 10 p.

Research output: Contribution to journalArticle

Cryptosporidium parvum
NF-kappa B
Epithelium
Epithelial Cells
Apoptosis
59 Citations (Scopus)

Cryptosporidium parvum attachment to and internalization by human biliary epithelia in vitro: A morphologic study

Huang, B. Q., Chen, X. M. & La Russo, N. F., Apr 2004, In : Journal of Parasitology. 90, 2, p. 212-221 10 p.

Research output: Contribution to journalArticle

Cryptosporidium parvum
parasite
Parasites
epithelium
Epithelium
83 Citations (Scopus)
Cryptosporidium parvum
Fas Ligand Protein
Epithelium
Apoptosis
Neutralizing Antibodies
28 Citations (Scopus)

Cryptosporidium parvum infects human cholangiocytes via sphingolipid-enriched membrane microdomains

Nelson, J. B., O'hara, S. P., Small, A. J., Tietz, P. S., Choudhury, A. K., Pagano, R. E., Chen, X. M. & La Russo, N. F., Dec 2006, In : Cellular Microbiology. 8, 12, p. 1932-1945 14 p.

Research output: Contribution to journalArticle

Membrane Microdomains
Cryptosporidium parvum
Sphingolipids
Membranes
Sphingomyelin Phosphodiesterase
56 Citations (Scopus)

Cryptosporidium parvum invasion of biliary epithelia requires host cell tyrosine phosphorylation of cortactin via c-Src

Chen, X. M., Huang, B. Q., Splinter, P. L., Cao, H., Zhu, G., Mc Niven, M. A. & La Russo, N. F., Jul 1 2003, In : Gastroenterology. 125, 1, p. 216-228 13 p.

Research output: Contribution to journalArticle

Cortactin
Cryptosporidium parvum
Tyrosine
Epithelium
Phosphorylation
68 Citations (Scopus)

Cryptosporidium parvum is cytopathic for cultured human biliary epithelia via an apoptotic mechanism

Chen, X. M., Levine, S. A., Tietz, P., Krueger, E., Mc Niven, M. A., Jefferson, D. M., Mahle, M. & La Russo, N. F., 1998, In : Hepatology. 28, 4 I, p. 906-913 8 p.

Research output: Contribution to journalArticle

Cryptosporidium parvum
Epithelium
Cryptosporidiosis
Sporozoites
Sclerosing Cholangitis
8 Citations (Scopus)

Current therapies and clinical controversies in the management of primary sclerosing cholangitis.

Prall, R. T., Lindor, K. D., Wiesner, R. H. & La Russo, N. F., Apr 2000, In : Current Gastroenterology Reports. 2, 2, p. 99-103 5 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Liver Transplantation
Intrahepatic Bile Ducts
Extrahepatic Bile Ducts
Cholangiocarcinoma
91 Citations (Scopus)

Cyclic AMP Regulates Bicarbonate Secretion in Cholangiocytes Through Release of ATP Into Bile

Minagawa, N., Nagata, J., Shibao, K., Masyuk, A. I., Gomes, D. A., Rodrigues, M. A., Lesage, G., Akiba, Y., Kaunitz, J. D., Ehrlich, B. E., La Russo, N. F. & Nathanson, M. H., Nov 2007, In : Gastroenterology. 133, 5, p. 1592-1602 11 p.

Research output: Contribution to journalArticle

Bicarbonates
Bile
Cyclic AMP
Intrahepatic Bile Ducts
Adenosine Triphosphate
100 Citations (Scopus)

Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes

Spirlì, C., Fabris, L., Duner, E., Fiorotto, R., Ballardini, G., Roskams, T., La Russo, N. F., Sonzogni, A., Okolicsanyi, L. & Strazzabosco, M., Mar 1 2003, In : Gastroenterology. 124, 3, p. 737-753 17 p.

Research output: Contribution to journalArticle

Adenylyl Cyclases
Cyclic AMP
Nitric Oxide
Cytokines
Cholestasis
24 Citations (Scopus)

Cytoskeletal and motor proteins facilitate trafficking of AQP1-containing vesicles in cholangiocytes

Tietz, P. S., Mc Niven, M. A., Splinter, P. L., Huang, B. Q. & La Russo, N. F., Jan 2006, In : Biology of the Cell. 98, 1, p. 43-52 10 p.

Research output: Contribution to journalArticle

Aquaporin 1
Cytoskeletal Proteins
Protein Transport
Dyneins
Kinesin
137 Citations (Scopus)

Defects in Cholangiocyte Fibrocystin Expression and Ciliary Structure in the PCK Rat

Masyuk, T. V., Huang, B. Q., Ward, C. J., Masyuk, A. I., Yuan, D., Splinter, P. L., Punyashthiti, R., Ritman, E. L., Torres, V., Harris, P. C. & La Russo, N. F., Nov 2003, In : Gastroenterology. 125, 5, p. 1303-1310 8 p.

Research output: Contribution to journalArticle

Cilia
Intrahepatic Bile Ducts
Small Interfering RNA
Polycystic Kidney Diseases
Cysts
1 Citation (Scopus)

Defining the relationship between antoimmune disease and primary sclerosing cholangitis

Talwalkar, J. A., La Russo, N. F. & Lindor, K. D., 2000, In : American Journal of Gastroenterology. 95, 11, p. 3024-3026 3 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
HLA Antigens
Inflammatory Bowel Diseases
Cellular Immunity
Autoimmune Diseases
1 Citation (Scopus)

Deoxycholic acid, but not chenodeoxycholic and cholic acids, inhibits intestinal absorption of cholesterol in man

Sama, C. & La Russo, N. F., 1980, In : Gastroenterology. 78, 5 II, p. 1250 1 p.

Research output: Contribution to journalArticle

Cholic Acids
Deoxycholic Acid
Intestinal Absorption
Cholesterol
72 Citations (Scopus)

Determinants of fasting and postprandial serum bile acid levels in healthy man

La Russo, N. F., Hoffman, N. E., Korman, M. G., Hofmann, A. F. & Cowen, A. E., May 1978, In : The American Journal of Digestive Diseases. 23, 5, p. 385-391 7 p.

Research output: Contribution to journalArticle

Bile Acids and Salts
Fasting
Serum
Glycocholic Acid
Enterohepatic Circulation
6 Citations (Scopus)

Development and application of methodology for assessing the role of lysosomes in experimental ulcerogenesis in the guinea pig

Nagorney, D. M., La Russo, N. F. & Dozois, R. R., 1983, In : Gastroenterology. 85, 3, p. 548-556 9 p.

Research output: Contribution to journalArticle

Lysosomes
Stomach
Guinea Pigs
Histamine
Gastric Mucosa
28 Citations (Scopus)

Development and characterization of a cholangiocyte cell line from the PCK rat, an animal model of Autosomal Recessive Polycystic Kidney Disease

Muff, M. A., Masyuk, T. V., Stroope, A. J., Huang, B. Q., Splinter, P. L., Lee, S. O. & La Russo, N. F., Sep 5 2006, In : Laboratory Investigation. 86, 9, p. 940-950 11 p.

Research output: Contribution to journalArticle

Autosomal Recessive Polycystic Kidney
Animal Models
Cell Line
Cysts
Cilia
33 Citations (Scopus)

Development and characterization of a rodent model of immune-mediated cholangitis

Ueno, Y., Phillips, J. O., Ludwig, J., Lichtman, S. N. & La Russo, N. F., Jan 9 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 1, p. 216-220 5 p.

Research output: Contribution to journalArticle

Cholangitis
Rodentia
Bovine Serum Albumin
Hepatocytes
Bile Ducts
7 Citations (Scopus)

Development and characterization of cholangioids from normal and diseased human cholangiocytes as an in vitro model to study primary sclerosing cholangitis

Loarca, L., De Assuncao, T. M., Jalan-Sakrikar, N., Bronk, S., Krishnan, A., Huang, B., Morton, L., Trussoni, C., Bonilla, L. M., Krueger, E., O'Hara, S., Splinter, P., Shi, G., Pisarello, M. J. L., Gores, G. J., Huebert, R. C. & La Russo, N. F., Nov 1 2017, In : Laboratory Investigation. 97, 11, p. 1385-1396 12 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Macrophages
Bile Duct Diseases
Keratin-7
Keratin-19
105 Citations (Scopus)

Development and characterization of polarized primary cultures of rat intrahepatic bile duct epithelial cells

Vroman, B. & La Russo, N. F., Jan 1996, In : Laboratory Investigation. 74, 1, p. 303-313 11 p.

Research output: Contribution to journalArticle

Intrahepatic Bile Ducts
Epithelial Cells
Keratin-7
Keratin-19
Scanning Transmission Electron Microscopy
52 Citations (Scopus)
Rodentia
Apoptosis
Caspase 1
Peptide Hydrolases
In Vitro Techniques
58 Citations (Scopus)
Taurine
High performance liquid chromatography
Bile Acids and Salts
Bile
Glycine
34 Citations (Scopus)

Development of an intravenous bile acid tolerance test: plasma disappearance of cholylglycine in health

Korman, M. G., La Russo, N. F., Hoffman, N. E. & Hofmann, A. F., 1975, In : New England Journal of Medicine. 292, 23, p. 1205-1209 5 p.

Research output: Contribution to journalArticle

Glycocholic Acid
Bile Acids and Salts
Cholic Acid
Colic
Liver
53 Citations (Scopus)

Diagnosis and treatment of primary sclerosing cholangitis.

Wiesner, R. H., Ludwig, J., La Russo, N. F. & MacCarty, R. L., Aug 1985, In : Seminars in Liver Disease. 5, 3, p. 241-253 13 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Biliary Tract Surgical Procedures
Bile Duct Neoplasms
Avitaminosis
Therapeutics
184 Citations (Scopus)

Diagnostic role of serum CA 19-9 for cholangiocarcinoma in patients with primary sclerosing cholangitis

Nichols, J. C., Gores, G. J., La Russo, N. F., Wiesner, R. H., Nagorney, D. M. & Ritts, R. E., 1993, In : Mayo Clinic Proceedings. 68, 9, p. 874-879 6 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangiocarcinoma
Serum
Immunoradiometric Assay
Neoplasm Antigens
10 Citations (Scopus)

Differential expression of cholangiocyte and ileal bile acid transporters following bile acid supplementation and depletion

Kip, N. S., Lazaridis, K. N., Masyuk, A. I., Splinter, P. L., Huebert, R. C. & La Russo, N. F., May 15 2004, In : World Journal of Gastroenterology. 10, 10, p. 1440-1446 7 p.

Research output: Contribution to journalArticle

Taurocholic Acid
Bile Acids and Salts
Cholestyramine Resin
Diet
Intrahepatic Bile Ducts
30 Citations (Scopus)

Different susceptibility of mice to immune-mediated cholangitis induced by immunization with carbonic anhydrase II

Ueno, Y., Ishii, M., Takahashi, S., Igarashi, T., Toyota, T. & La Russo, N. F., May 1998, In : Laboratory Investigation. 78, 5, p. 629-637 9 p.

Research output: Contribution to journalArticle

Carbonic Anhydrase II
Cholangitis
Immunization
Inbred DBA Mouse
Bovine Serum Albumin
40 Citations (Scopus)

Differing effects of ursodeoxycholic or chenodeoxycholic acid on biliary cholesterol saturation and bile acid metabolism in man - A dose-response study

Thistle, J. L., La Russo, N. F., Hofmann, A. F., Turcotte, J., Carlson, G. L. & Ott, B. J., Feb 1982, In : Digestive Diseases and Sciences. 27, 2, p. 161-168 8 p.

Research output: Contribution to journalArticle

Chenodeoxycholic Acid
Ursodeoxycholic Acid
Bile Acids and Salts
Cholesterol
Gallstones
18 Citations (Scopus)

Dissociation of bile flow and biliary lipid secretion from biliary lysosomal enzyme output in experimental cholestasis

Lopez del Pino, V. H. & La Russo, N. F., 1981, In : Journal of Lipid Research. 22, 2, p. 229-235 7 p.

Research output: Contribution to journalArticle

Acetylglucosaminidase
Ethinyl Estradiol
Glucuronidase
beta-Galactosidase
Liver
8 Citations (Scopus)

Distribution of Cryptosporidium parvum sporozoite apical organelles during attachment to and internalization by cultured biliary epithelial cells

O'Hara, S. P., Huang, B. Q., Chen, X. M., Nelson, J. & La Russo, N. F., Oct 2005, In : Journal of Parasitology. 91, 5, p. 995-999 5 p.

Research output: Contribution to journalArticle

Cryptosporidium parvum
Sporozoites
sporozoites
Organelles
organelles
54 Citations (Scopus)

Diurnal serum levels of primary conjugated bile acids. Assessment by specific radioimmunoassays for conjugates of cholic and chenodeoxycholic acid

Schalm, S. W., La Russo, N. F., Hofmann, A. F., Hoffman, N. E., van Berge-Henegouwen, G. P. & Korman, M. G., 1978, In : Gut. 19, 11, p. 1006-1014 9 p.

Research output: Contribution to journalArticle

Cholic Acid
Bile Acids and Salts
Radioimmunoassay
Serum
Enterohepatic Circulation
1 Citation (Scopus)

Doublecortin domain containing protein 2 (DCDC2) genetic variants in primary sclerosing cholangitis

Cheung, A. C., Juran, B. D., Moore, R. M., La Russo, N. F. & Lazaridis, K. N., 2017, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Protein Domains
30 Citations (Scopus)

Dynamic measurements of the acute and chronic effects of lysosomotropic agents on hepatocyte lysosomal pH using flow cytometry

Myers, B. M., Tietz, P. S., Tarara, J. E. & La Russo, N. F., 1995, In : Hepatology. 22, 5, p. 1519-1526 8 p.

Research output: Contribution to journalArticle

Hepatocytes
Flow Cytometry
Lysosomes
Chloroquine
Video Microscopy
132 Citations (Scopus)
Glycocholic Acid
Liver Circulation
Malabsorption Syndromes
Enterohepatic Circulation
Cholic Acid

Editorial: Hepatic drug metabolism and malignancy.

La Russo, N. F., Oct 4 1976, In : Journal of the American Medical Association. 236, 14, p. 1612-1613 2 p.

Research output: Contribution to journalArticle

Carbon Radioisotopes
N Demethylating Oxidoreductases
Aminopyrine
Breath Tests
Liver Neoplasms
14 Citations (Scopus)

Effective dissolution of biliary duct stones by intraductal infusion of mono octanoin

Thistle, J. L., Carlson, G. L., La Russo, N. F. & Hofmann, A. F., 1978, In : Gastroenterology. 74, 5 II, p. 1103 1 p.

Research output: Contribution to journalArticle

monooctanoin

Effect of acute administration of bile acids on biliary lipid secretion in man

Sama, C., La Russo, N. F., Lopez, V. & Thistle, J. L., 1981, In : Italian Journal of Gastroenterology. 13, 1, p. 73-74 2 p.

Research output: Contribution to journalArticle

Bile Acids and Salts
Lipids
33 Citations (Scopus)
Chloroquine
Lysosomes
Hepatocytes
Lipids
Liver
22 Citations (Scopus)
Cholic Acids
Intestinal Absorption
Cholesterol
Deoxycholic Acid
Gallstones
84 Citations (Scopus)

Effect of deoxycholic acid ingestion on bile acid metabolism and biliary lipid secretion in normal subjects

La Russo, N. F., Szczepanik, P. A. & Hofmann, A. F., 1977, In : Gastroenterology. 72, 1, p. 132-140 9 p.

Research output: Contribution to journalArticle

Deoxycholic Acid
Bile Acids and Salts
Lipid Metabolism
Eating
Cholesterol
25 Citations (Scopus)

Effect of litholytic bile acids on cholesterol absorption in gallstone patients

La Russo, N. F. & Thistle, J. L., 1983, In : Gastroenterology. 84, 2, p. 265-271 7 p.

Research output: Contribution to journalArticle

Chenodeoxycholic Acid
Gallstones
Ursodeoxycholic Acid
Bile Acids and Salts
Cholesterol
110 Citations (Scopus)

Effect of primary bile acid ingestion on bile acid metabolism and biliary lipid secretion in gallstone patients

La Russo, N. F., Hoffman, N. E., Hofmann, A. F., Northfield, T. C. & Thistle, J. L., 1975, In : Gastroenterology. 69, 6, p. 1301-1314 14 p.

Research output: Contribution to journalArticle

Gallstones
Bile Acids and Salts
Lipid Metabolism
Chenodeoxycholic Acid
Eating
124 Citations (Scopus)

Effect of proctocolectomy for chronic ulcerative colitis on the natural history of primary sclerosing cholangitis

Cangemi, J. R., Wiesner, R. H., Beaver, S. J., Ludwig, J., MacCarty, R. L., Dozois, R. R., Zinsmeister, A. R. & La Russo, N. F., Jan 1 1989, In : Gastroenterology. 96, 3, p. 790-794 5 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Ulcerative Colitis
Liver
Hepatomegaly
Esophageal and Gastric Varices
33 Citations (Scopus)

Effects of acute bile acid administration on biliary lipid secretion in healthy volunteers

Sama, C., La Russo, N. F., Lopez del Pino, V. & Thistle, J. L., 1982, In : Gastroenterology. 82, 3, p. 515-525 11 p.

Research output: Contribution to journalArticle

Bile Acids and Salts
Healthy Volunteers
Phospholipids
Lipids
Cholesterol
1 Citation (Scopus)

Efficacy and safety of curcumin in primary sclerosing cholangitis: an open label pilot study

Eaton, J. E., Nelson, K. M., Gossard, A. A., Carey, E. J., Tabibian, J. H., Lindor, K. D. & La Russo, N. F., Jan 1 2019, In : Scandinavian Journal of Gastroenterology.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Curcumin
Alkaline Phosphatase
Safety
Serum
73 Citations (Scopus)

Efficacy and safety of transarterial radioembolization versus chemoembolization in patients with hepatocellular carcinoma

Moreno-Luna, L. E., Yang, J. D., Sanchez, W., Paz-Fumagalli, R., Harnois, D., Mettler, T. A., Gansen, D. N., De Groen, P. C., Lazaridis, K. N., Narayanan Menon, K. V., La Russo, N. F., Alberts, S. R., Gores, G. J., Fleming, C. J., Slettedahl, S. W., Harmsen, W. S., Therneau, T. M., Wiseman, G. A., Andrews, J. C. & Roberts, L. R., Jun 2013, In : CardioVascular and Interventional Radiology. 36, 3, p. 714-723 10 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Safety
Fatigue
Fever
Therapeutics
14 Citations (Scopus)

Efficacy of 4 Years of Octreotide Long-Acting Release Therapy in Patients with Severe Polycystic Liver Disease

Hogan, M. C., Masyuk, T., Bergstralh, E., Li, B., Kremers, W. K., Vaughan, L. E., Ihrke, A., Severson, A. L., Irazabal Mira, M., Glockner, J., La Russo, N. F. & Torres, V., Aug 1 2015, In : Mayo Clinic Proceedings. 90, 8, p. 1030-1037 8 p.

Research output: Contribution to journalArticle

Octreotide
Autosomal Dominant Polycystic Kidney
Quality of Life
Glomerular Filtration Rate
Therapeutics
1 Citation (Scopus)

Electropermeabilization: getting inside the cell to study autophagy.

Yamazaki, K. & La Russo, N. F., Mar 1988, In : Hepatology. 8, 2, p. 418-419 2 p.

Research output: Contribution to journalArticle

Cytological Techniques
Electroporation
Autophagy
Lysosomes
Phagocytosis
117 Citations (Scopus)

Elevated circulating immune complexes in primary sclerosing cholangitis

Bodenheimer, J. C., La Russo, N. F., Thayer, W. R., Charland, C., Staples, P. J. & Ludwig, J., 1983, In : Hepatology. 3, 2, p. 150-154 5 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Antigen-Antibody Complex
Inflammatory Bowel Diseases
Serum
Ulcerative Colitis
4 Citations (Scopus)

Emerging pharmacologic therapies for primary sclerosing cholangitis

Cheung, A. C., Lazaridis, K. N., La Russo, N. F. & Gores, G. J., Mar 2 2017, (Accepted/In press) In : Current Opinion in Gastroenterology.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Immunomodulation
Microbiota
Pharmaceutical Preparations
Liver Transplantation