• 26904 Citations
  • 93 Scopus h-Index
1973 …2019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1973 2019

Filter
Article
3 Citations (Scopus)

Calcium signaling in cilia and ciliary-mediated intracellular calcium signaling: Are they independent or coordinated molecular events?

Masyuk, A. I., Gradilone, S. A. & La Russo, N. F., Nov 1 2014, In : Hepatology. 60, 5, p. 1783-1785 3 p.

Research output: Contribution to journalArticle

Calcium Signaling
Cilia
38 Citations (Scopus)

Cdc42 and the Actin-Related Protein/Neural Wiskott-Aldrich Syndrome Protein Network Mediate Cellular Invasion by Cryptosporidium parvum

Chen, X. M., Huang, B. Q., Splinter, P. L., Orth, J. D., Billadeau, D. D., Mc Niven, M. A. & La Russo, N. F., May 2004, In : Infection and Immunity. 72, 5, p. 3011-3021 11 p.

Research output: Contribution to journalArticle

Wiskott-Aldrich Syndrome Protein
Cryptosporidium parvum
Actins
Proteins
Parasites
228 Citations (Scopus)

Cellular and subcellular localization of the ARPKD protein; fibrocystin is expressed on primary cilia

Ward, C. J., Yuan, D., Masyuk, T. V., Wang, X., Punyashthiti, R., Whelan, S., Bacallao, R., Torra, R., La Russo, N. F., Torres, V. & Harris, P. C., Oct 15 2003, In : Human Molecular Genetics. 12, 20, p. 2703-2710 8 p.

Research output: Contribution to journalArticle

Autosomal Recessive Polycystic Kidney
Cilia
Proteins
Kidney
Monoclonal Antibodies
8 Citations (Scopus)

Centers, institutes, and the future of clinical departments: Part II.

Crist, T. B., La Russo, N. F., Meyers, F. J., Clayton, C. P. & Ibrahim, T., Dec 15 2003, In : The American journal of medicine. 115, 9, p. 745-747 3 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Centers, Institutes, and the future of clinical departments: part I.

Ibrahim, T., O'Connell, J. B., La Russo, N. F., Meyers, F. J. & Crist, T. B., Sep 2003, In : The American journal of medicine. 115, 4, p. 337-341 5 p.

Research output: Contribution to journalArticle

Interdepartmental Relations
Hospital Departments
Internal Medicine
Decision Making
13 Citations (Scopus)

Centrosomal abnormalities characterize human and rodent cystic cholangiocytes and are associated with Cdc25A overexpression

Masyuk, T. V., Lee, S. O., Radtke, B. N., Stroope, A. J., Huang, B., Banales, J. M., Masyuk, A. I., Splinter, P. L., Gradilone, S. A., Gajdos, G. B. & La Russo, N. F., Jan 2014, In : American Journal of Pathology. 184, 1, p. 110-121 12 p.

Research output: Contribution to journalArticle

Centrosome
Cilia
Rodentia
Cell Cycle
Cysts
19 Citations (Scopus)

Channel-mediated water movement across enclosed or perfused mouse intrahepatic bile duct units

Gong, A. Y., Masyuk, A. I., Splinter, P. L., Huebert, R. C., Tietz, P. S. & La Russo, N. F., 2002, In : American Journal of Physiology - Cell Physiology. 283, 1 52-1

Research output: Contribution to journalArticle

Water Movements
Intrahepatic Bile Ducts
Ducts
Water
Aquaporins
13 Citations (Scopus)
Intrahepatic Bile Ducts
Ducts
Rats
Epithelial Cells
Cells
23 Citations (Scopus)

Characterization of apical and basolateral plasma membrane domains derived from cultured rat cholangiocytes

Tietz, P., Levine, S., Holman, R., Fretham, C. & La Russo, N. F., Dec 15 1997, In : Analytical Biochemistry. 254, 2, p. 192-199 8 p.

Research output: Contribution to journalArticle

Cell membranes
Rats
Cell Membrane
Isopycnic Centrifugation
Intrahepatic Bile Ducts
39 Citations (Scopus)

Characterization of cultured cholangiocytes isolated from livers of patients with primary sclerosing cholangitis

Tabibian, J. H., Trussoni, C. E., O'Hara, S. P., Splinter, P. L., Heimbach, J. K. & La Russo, N. F., Jan 1 2014, In : Laboratory Investigation. 94, 10, p. 1126-1133 8 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Liver
Electric Impedance
Cell Adhesion
Epithelial Cells
187 Citations (Scopus)

Characterization of PKD protein-positive exosome-like vesicles

Hogan, M. C., Manganelli, L., Woollard, J. R., Masyuk, A. I., Masyuk, T. V., Tammachote, R., Huang, B. Q., Leontovich, A. A., Beito, T. G., Madden, B. J., Charlesworth, M. C., Torres, V., La Russo, N. F., Harris, P. C. & Ward, C. J., Feb 2009, In : Journal of the American Society of Nephrology. 20, 2, p. 278-288 11 p.

Research output: Contribution to journalArticle

Exosomes
Cilia
Proteomics
Proteins
Autosomal Recessive Polycystic Kidney
4 Citations (Scopus)

Charcoal hemoperfusion in the treatment of medically refractory pruritus in cholestatic liver disease

Kittanamongkolchai, W., El-Zoghby, Z. M., Eileen Hay, J., Wiesner, R. H., Kamath, P. S., La Russo, N. F., Watt, K. D., Cramer, C. H. & Leung, N., Dec 8 2016, (Accepted/In press) In : Hepatology International. p. 1-6 6 p.

Research output: Contribution to journalArticle

Hemoperfusion
Charcoal
Pruritus
Liver Diseases
Therapeutics
303 Citations (Scopus)

Cholangiocarcinoma complicating primary sclerosing cholangitis

Rosen, C. B., Nagorney, D. M., Wiesner, R. H., Coffey, R. J. & La Russo, N. F., 1991, In : Annals of Surgery. 213, 1, p. 21-25 5 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangiocarcinoma
Jaundice
Liver Transplantation
Weight Loss
102 Citations (Scopus)

Cholangiocarcinoma complicating primary sclerosing cholangitis: Cholangiographic appearances

MacCarty, R. L., La Russo, N. F., May, G. R., Bender, C. E., Wiesner, R. H., King, J. E. & Coffey, R. J., 1985, In : Radiology. 156, 1, p. 43-46 4 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangiocarcinoma
Dilatation
Carcinoma
Pathologic Constriction
65 Citations (Scopus)

Cholangiocarcinomas express Fas ligand and disable the Fas receptor

Que, F., Phan, V. A., Phan, V. H., Celli, A., Batts, K., La Russo, N. F. & Gores, G. J., 1999, In : Hepatology. 30, 6, p. 1398-1404 7 p.

Research output: Contribution to journalArticle

CD95 Antigens
Fas Ligand Protein
Cholangiocarcinoma
Apoptosis
Cell Death
59 Citations (Scopus)

Cholangiociliopathies: Genetics, molecular mechanisms and potential therapies

Masyuk, T., Masyuk, A. & La Russo, N. F., May 2009, In : Current Opinion in Gastroenterology. 25, 3, p. 265-271 7 p.

Research output: Contribution to journalArticle

Molecular Biology
Cysts
Liver
MicroRNAs
Therapeutics
6 Citations (Scopus)

Cholangiocyte autophagy contributes to hepatic cystogenesis in polycystic liver disease and represents a potential therapeutic target

Masyuk, A. I., Masyuk, T. V., Lorenzo Pisarello, M. J., Ding, J. F., Loarca, L., Huang, B. Q. & La Russo, N. F., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Autophagy
Liver
Hydroxychloroquine
Polycystic Kidney Diseases
Therapeutics
5 Citations (Scopus)

Cholangiocyte bile salt transporters in cholesterol gallstone-susceptible and resistant inbred mouse strains

Liu, J. J., Glickman, J. N., Masyuk, A. I. & La Russo, N. F., 2008, In : Journal of Gastroenterology and Hepatology (Australia). 23, 10, p. 1596-1602 7 p.

Research output: Contribution to journalArticle

Inbred Strains Mice
Gallstones
Bile Acids and Salts
Cholesterol
Inbred AKR Mouse
1 Citation (Scopus)

Cholangiocyte biology

Tietz, P. & La Russo, N. F., May 2003, In : Current Opinion in Gastroenterology. 19, 3, p. 264-269 6 p.

Research output: Contribution to journalArticle

Ion Transport
Gene Silencing
Cytoskeleton
Knockout Mice
Liver Diseases
3 Citations (Scopus)

Cholangiocyte biology

Tietz, P. S. & La Russo, N. F., May 2004, In : Current Opinion in Gastroenterology. 20, 3, p. 270-274 5 p.

Research output: Contribution to journalArticle

Cholestasis
Bile
Theoretical Models
Technology
Animal Disease Models
2 Citations (Scopus)

Cholangiocyte biology

Tietz, P. S. & La Russo, N. F., May 2005, In : Current Opinion in Gastroenterology. 21, 3, p. 337-343 7 p.

Research output: Contribution to journalArticle

Bile
Technology
Theoretical Models
Cholestasis
Ion Transport
36 Citations (Scopus)

Cholangiocyte biology

Bogert, P. T. & La Russo, N. F., May 2007, In : Current Opinion in Gastroenterology. 23, 3, p. 299-305 7 p.

Research output: Contribution to journalArticle

Technology
Investigational Therapies
Cholestasis
Ion Transport
Gene Silencing
2 Citations (Scopus)

Cholangiocyte biology

Tietz, P. & La Russo, N. F., 2002, In : Current Opinion in Gastroenterology. 18, 3, p. 360-365 6 p.

Research output: Contribution to journalArticle

Bile Ducts
Biliary Tract
Bile
Theoretical Models
Software
17 Citations (Scopus)

Cholangiocyte biology

Tietz, P. S. & La Russo, N. F., May 2006, In : Current Opinion in Gastroenterology. 22, 3, p. 279-287 9 p.

Research output: Contribution to journalArticle

Technology
Cholestasis
Ion Transport
Gene Silencing
Bile
179 Citations (Scopus)

Cholangiocyte Cilia Detect Changes in Luminal Fluid Flow and Transmit Them Into Intracellular Ca2+ and cAMP Signaling

Masyuk, A. I., Masyuk, T. V., Splinter, P. L., Huang, B. Q., Stroope, A. J. & La Russo, N. F., Sep 2006, In : Gastroenterology. 131, 3, p. 911-920 10 p.

Research output: Contribution to journalArticle

Cilia
Intrahepatic Bile Ducts
Bile
Organelles
Protein Isoforms
127 Citations (Scopus)

Cholangiocyte cilia express TRPV4 and detect changes in luminal tonicity inducing bicarbonate secretion

Gradilone, S. A., Masyuk, A. I., Splinter, P. L., Banales, J. M., Huang, B. Q., Tietz, P. S., Masyuk, T. V. & La Russo, N. F., Nov 27 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 48, p. 19138-19143 6 p.

Research output: Contribution to journalArticle

Cilia
Bicarbonates
Bile
Adenosine Triphosphate
Intrahepatic Bile Ducts
9 Citations (Scopus)

Cholangiocyte myosin IIB is required for localized aggregation of sodium glucose cotransporter 1 to sites of Cryptosporidium parvum cellular invasion and facilitates parasite internalization

O'Hara, S. P., Gajdos, G. B., Trussoni, C. E., Splinter, P. L. & La Russo, N. F., Jul 2010, In : Infection and Immunity. 78, 7, p. 2927-2936 10 p.

Research output: Contribution to journalArticle

Sodium-Glucose Transporter 1
Nonmuscle Myosin Type IIB
Cryptosporidium parvum
Parasites
Cell Surface Extensions
42 Citations (Scopus)

Cholangiocyte N-Ras protein mediates lipopolysaccharide-induced interleukin 6 secretion and proliferation

O'Hara, S. P., Splinter, P. L., Trussoni, C. E., Gajdos, G. B., Lineswala, P. N. & La Russo, N. F., Sep 2 2011, In : Journal of Biological Chemistry. 286, 35, p. 30352-30360 9 p.

Research output: Contribution to journalArticle

ras Proteins
Toll-Like Receptors
Lipopolysaccharides
Interleukin-6
Chemical activation
105 Citations (Scopus)

Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptors

Masyuk, A. I., Gradilone, S. A., Banales, J. M., Huang, B. Q., Masyuk, T. V., Lee, S. O., Splinter, P. L., Stroope, A. J. & La Russo, N. F., Oct 2008, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 295, 4

Research output: Contribution to journalArticle

Purinergic P2Y12 Receptors
Cilia
Organelles
Nucleotides
Intrahepatic Bile Ducts
87 Citations (Scopus)

Cholangiocyte primary cilia in liver health and disease

Masyuk, A. I., Masyuk, T. V. & La Russo, N. F., Aug 2008, In : Developmental Dynamics. 237, 8, p. 2007-2012 6 p.

Research output: Contribution to journalArticle

Cilia
Liver Diseases
Health
Intrahepatic Bile Ducts
Mutation
7 Citations (Scopus)

Cholangiocytes and the environment in primary sclerosing cholangitis: Where is the link?

O'Hara, S. P., Karlsen, T. H. & La Russo, N. F., Nov 1 2017, In : Gut. 66, 11, p. 1873-1877 5 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangiocarcinoma
Environmental Health
Epithelial Cells
87 Citations (Scopus)

Cholangiocyte senescence by way of N-Ras activation is a characteristic of primary sclerosing cholangitis

Tabibian, J. H., O'Hara, S. P., Splinter, P. L., Trussoni, C. E. & La Russo, N. F., 2014, In : Hepatology. 59, 6, p. 2263-2275 13 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Phenotype
Cholestanes
Secretory Component
Biliary Liver Cirrhosis
108 Citations (Scopus)

Cholangiocytes express the aquaporin CHIP and transport water via a channel-mediated mechanism

Roberts, S. K., Yano, M., Ueno, Y., Pham, L., Alpini, G., Agre, P. & La Russo, N. F., Dec 20 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 26, p. 13009-13013 5 p.

Research output: Contribution to journalArticle

Aquaporin 1
Water Movements
Aquaporins
Intrahepatic Bile Ducts
Mercuric Chloride

Cholangiocytes in health and disease: From basic science to novel treatments

Banales, J. M., Marzioni, M., La Russo, N. F. & Jansen, P., Jan 1 2018, (Accepted/In press) In : Biochimica et Biophysica Acta - Molecular Basis of Disease.

Research output: Contribution to journalArticle

Health
11 Citations (Scopus)

Cholangiocyte-specific rat liver proteins identified by establishment of a two-dimensional gel protein database

Tietz, P., De Groen, P. C., Anderson, N. L., Sims, C., Esquer-Blasco, R., Meheus, L., Raymackers, J., Dauwe, M. & La Russo, N. F., 1998, In : Electrophoresis. 19, 18, p. 3207-3212 6 p.

Research output: Contribution to journalArticle

Protein Databases
Liver
Rats
Gels
Proteins
97 Citations (Scopus)

Cholelitholysis using methyl tertiary butyl ether

Allen, M. J., Borody, T. J., Bugliosi, T. F., May, G. R., La Russo, N. F. & Thistle, J. L., Jan 1985, In : Gastroenterology. 88, 1 PART 1, p. 122-125 4 p.

Research output: Contribution to journalArticle

Ether
Gallstones
Gallbladder
Cholesterol
Dogs
60 Citations (Scopus)

Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling

Masyuk, A. I., Huang, B. Q., Radtke, B. N., Gajdos, G. B., Splinter, P. L., Masyuk, T. V., Gradilone, S. A. & La Russo, N. F., 2013, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 304, 11

Research output: Contribution to journalArticle

Bile Acids and Salts
Cilia
Nuclear Envelope
GTP-Binding Proteins
Rodentia
31 Citations (Scopus)

Circadian rhythms of biliary protein and lipid excretion in rats

Nakano, A., Tietz, P. S. & La Russo, N. F., 1990, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 258, 5 21-5

Research output: Contribution to journalArticle

Circadian Rhythm
Bile
Lipids
Bile Acids and Salts
Proteins
36 Citations (Scopus)

Clinicopathological correlates of aspartyl (asparaginyl) β-hydroxylase over-expression in cholangiocarcinoma

Maeda, T., Taguchi, K. I., Aishima, S. I., Shimada, M., Hintz, D., La Russo, N. F., Gores, G. J., Tsuneyoshi, M., Sugimachi, K., Wands, J. R. & Monte, S. M. D. L., 2004, In : Cancer Detection and Prevention. 28, 5, p. 313-318 6 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Mixed Function Oxygenases
Sclerosing Cholangitis
Neoplasms
Growth
482 Citations (Scopus)

Clinicopathologic features of the syndrome of primary sclerosing cholangitis

Wiesner, R. H. & La Russo, N. F., 1980, In : Gastroenterology. 79, 2, p. 200-206 7 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangiography
Cholestasis
Liver Failure
Liver
17 Citations (Scopus)

Cloning and expression of SLC10A4, a putative organic anion transport protein

Splinter, P. L., Lazaridis, K. N., Dawson, P. A. & La Russo, N. F., Nov 14 2006, In : World Journal of Gastroenterology. 12, 42, p. 6797-6805 9 p.

Research output: Contribution to journalArticle

Organic Anion Transporters
CHO Cells
Organism Cloning
Taurocholic Acid
Tissue Distribution
2 Citations (Scopus)

Combination of a Histone Deacetylase 6 Inhibitor and a Somatostatin Receptor Agonist Synergistically Reduces Hepatorenal Cystogenesis in an Animal Model of Polycystic Liver Disease

Lorenzo Pisarello, M., Masyuk, T. V., Gradilone, S. A., Masyuk, A. I., Ding, J. F., Lee, P. Y. & La Russo, N. F., Apr 1 2018, In : American Journal of Pathology. 188, 4, p. 981-994 14 p.

Research output: Contribution to journalArticle

Somatostatin Receptors
Histone Deacetylase Inhibitors
Polycystic Kidney Diseases
Histone Deacetylases
Animal Models
59 Citations (Scopus)

Comparison of surgical treatment of ulcerative colitis associated with primary sclerosing cholangitis: Ileal pouch-anal anastomosis versus Brooke ileostomy

Kartheuser, A. H., Dozois, R. R., La Russo, N. F., Wiesner, R. H., Ilstrup, D. M. & Schleck, C. D., 1996, In : Mayo Clinic Proceedings. 71, 8, p. 748-756 9 p.

Research output: Contribution to journalArticle

Colonic Pouches
Sclerosing Cholangitis
Ileostomy
Ulcerative Colitis
Therapeutics
171 Citations (Scopus)

Comparison of the clinicopathologic features of primary sclerosing cholangitis and primary biliary cirrhosis

Wiesner, R. H., La Russo, N. F., Ludwig, J. & Dickson, E. R., 1985, In : Gastroenterology. 88, 1 I, p. 108-114 7 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Biliary Liver Cirrhosis
Intrahepatic Bile Ducts
Extrahepatic Bile Ducts
Pruritus
48 Citations (Scopus)

Complications and risk factors after ileal pouch-anal anastomosis for ulcerative colitis associated with primary sclerosing cholangitis

Kartheuser, A. H., Dozois, R. R., Wiesner, R. H., La Russo, N. F., Ilstrup, D. M. & Schleck, C. D., 1993, In : Annals of Surgery. 217, 4, p. 314-320 7 p.

Research output: Contribution to journalArticle

Colonic Pouches
Sclerosing Cholangitis
Ulcerative Colitis
Hemorrhage
Ileostomy
1 Citation (Scopus)

COMPLICATIONS ET FACTEURS DE RISQUE DE L'ANASTOMOSE ILEO-ANALE AVEC RESERVOIR POUR RECTOCOLIE ULCERO-HEMORRAGIQUE ASSOCIEE A UNE CHOLANGITE SCLEROSANTE PRIMITIVE

Translated title of the contribution: Complications and risk factors after ileal pouch-anal anastomosis for ulcerative colitis associated with primary sclerosing cholangitisKartheuser, A. H., Dozois, R. R., Wiesner, R. H., La Russo, N. F., Ilstrup, D. M. & Schleck, C. D., 1993, In : Annales de Chirurgie. 47, 10, p. 1000-1008 9 p.

Research output: Contribution to journalArticle

Ileal Diseases
Restorative Proctocolectomy
Colonic Pouches
Sclerosing Cholangitis
Ileostomy
6 Citations (Scopus)

Computed tomography and peritoneoscopy for detection of liver metastases: Review of Mayo Clinic experience

Danielson, K. S., Sheedy, P. F., Stephens, D. H., Hattery, R. R. & La Russo, N. F., 1983, In : Journal of Computer Assisted Tomography. 7, 2, p. 230-234 5 p.

Research output: Contribution to journalArticle

Laparoscopy
Tomography
Neoplasm Metastasis
Liver
Biopsy
69 Citations (Scopus)

Coordinate secretion of acid hydrolases in rat bile. Hepatocyte exocytosis of lysosomal protein?

La Russo, N. F. & Fowler, S., 1979, In : Journal of Clinical Investigation. 64, 4, p. 948-954 7 p.

Research output: Contribution to journalArticle

Exocytosis
Hydrolases
Bile
Hepatocytes
Acids
1 Citation (Scopus)

Correspondence. Circulating Immune Complexes in Primary Sclerosing Cholangitis

Mihas, A. A., Volanakis, J. E., Schrohenloher, R. E., Mihas, T. A., Bodenheimer, H. C., La Russo, N. F., Thayer, W. R., Charland, C., Staples, P. J., Ludwig, J., Roggendorf, M., Deinhardt, F. & FrÖSner, G. G., 1984, In : Hepatology. 4, 2, p. 351-354 4 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Antigen-Antibody Complex
339 Citations (Scopus)

Cryptosporidiosis

Chen, X. M., Keithly, J. S., Paya, C. V. & La Russo, N. F., May 30 2002, In : New England Journal of Medicine. 346, 22, p. 1723-1731 9 p.

Research output: Contribution to journalArticle

AIDS-Related Opportunistic Infections
Cryptosporidiosis
Anti-HIV Agents
Cryptosporidium