• 27361 Citations
  • 94 Scopus h-Index
1973 …2020

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Article
2004

The cholangiopathies: Disorders of biliary epithelia

Lazaridis, K. N., Strazzabosco, M. & La Russo, N. F., Nov 2004, In : Gastroenterology. 127, 5, p. 1565-1577 13 p.

Research output: Contribution to journalArticle

261 Scopus citations
2003

Agonist-induced coordinated trafficking of functionally related transport proteins for water and ions in cholangiocytes

Tietz, P. S., Marinelli, R. A., Chen, X. M., Huang, B., Cohn, J., Kole, J., Mc Niven, M. A., Alper, S. & La Russo, N. F., May 30 2003, In : Journal of Biological Chemistry. 278, 22, p. 20413-20419 7 p.

Research output: Contribution to journalArticle

97 Scopus citations

ATP binding cassette transporter gene expression in rat liver progenitor cells

Ros, J. E., Roskams, T. A. D., Geuken, M., Havinga, R., Splinter, P. L., Petersen, B. E., La Russo, N. F., Van Der Kolk, D. M., Kuipers, F., Faber, K. N., Müller, M. & Jansen, P. L. M., Jul 1 2003, In : Gut. 52, 7, p. 1060-1067 8 p.

Research output: Contribution to journalArticle

50 Scopus citations

Cellular and subcellular localization of the ARPKD protein; fibrocystin is expressed on primary cilia

Ward, C. J., Yuan, D., Masyuk, T. V., Wang, X., Punyashthiti, R., Whelan, S., Bacallao, R., Torra, R., La Russo, N. F., Torres, V. & Harris, P. C., Oct 15 2003, In : Human Molecular Genetics. 12, 20, p. 2703-2710 8 p.

Research output: Contribution to journalArticle

232 Scopus citations

Centers, institutes, and the future of clinical departments: Part II.

Crist, T. B., La Russo, N. F., Meyers, F. J., Clayton, C. P. & Ibrahim, T., Dec 15 2003, In : The American journal of medicine. 115, 9, p. 745-747 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

Centers, Institutes, and the future of clinical departments: part I.

Ibrahim, T., O'Connell, J. B., La Russo, N. F., Meyers, F. J. & Crist, T. B., Sep 2003, In : The American journal of medicine. 115, 4, p. 337-341 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Cholangiocyte biology

Tietz, P. & La Russo, N. F., May 2003, In : Current Opinion in Gastroenterology. 19, 3, p. 264-269 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Cryptosporidium parvum invasion of biliary epithelia requires host cell tyrosine phosphorylation of cortactin via c-Src

Chen, X. M., Huang, B. Q., Splinter, P. L., Cao, H., Zhu, G., Mc Niven, M. A. & La Russo, N. F., Jul 1 2003, In : Gastroenterology. 125, 1, p. 216-228 13 p.

Research output: Contribution to journalArticle

56 Scopus citations

Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes

Spirlì, C., Fabris, L., Duner, E., Fiorotto, R., Ballardini, G., Roskams, T., La Russo, N. F., Sonzogni, A., Okolicsanyi, L. & Strazzabosco, M., Mar 1 2003, In : Gastroenterology. 124, 3, p. 737-753 17 p.

Research output: Contribution to journalArticle

102 Scopus citations

Defects in Cholangiocyte Fibrocystin Expression and Ciliary Structure in the PCK Rat

Masyuk, T. V., Huang, B. Q., Ward, C. J., Masyuk, A. I., Yuan, D., Splinter, P. L., Punyashthiti, R., Ritman, E. L., Torres, V., Harris, P. C. & La Russo, N. F., Nov 2003, In : Gastroenterology. 125, 5, p. 1303-1310 8 p.

Research output: Contribution to journalArticle

140 Scopus citations

Glucagon induces the plasma membrane insertion of functional aquaporin-8 water channels in isolated rat hepatocytes

Gradilone, S. A., García, F., Huebert, R. C., Tietz, P. S., Larocca, M. C., Kierbel, A., Carreras, F. I., La Russo, N. F. & Marinelli, R. A., Jun 1 2003, In : Hepatology. 37, 6, p. 1435-1441 7 p.

Research output: Contribution to journalArticle

72 Scopus citations

Hepatic artery and portal vein remodeling in rat liver: Vascular response to selective cholangiocyte proliferation

Masyuk, T. V., Ritman, E. L. & La Russo, N. F., Apr 1 2003, In : American Journal of Pathology. 162, 4, p. 1175-1182 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Improving attendance at medical grand rounds (multiple letters)

Kuo, D., Klainer, A. S., Reinharth, D., Dhatariya, K., Mueller, P., Litin, S. C., Sowden, M. L., Habermann, T. M. & La Russo, N. F., Jul 1 2003, In : Mayo Clinic Proceedings. 78, 7, p. 922-923 2 p.

Research output: Contribution to journalArticle

6 Scopus citations

Rat hepatocyte aquaporin-8 water channels are down-regulated in extrahepatic cholestasis

Carreras, F. I., Gradilone, S. A., Mazzone, A., García, F., Huang, B. Q., Ochoa, J. E., Tietz, P. S., La Russo, N. F., Calamita, G. & Marinelli, R. A., May 1 2003, In : Hepatology. 37, 5, p. 1026-1033 8 p.

Research output: Contribution to journalArticle

57 Scopus citations

Somatostatin stimulates ductal bile absorption and inhibits ductal bile secretion in mice via SSTR2 on cholangiocytes

Gong, A. Y., Tietz, P. S., Muff, M. A., Splinter, P. L., Huebert, R. C., Strowski, M. Z., Chen, X. M. & La Russo, N. F., May 1 2003, In : American Journal of Physiology - Cell Physiology. 284, 5 53-5

Research output: Contribution to journalArticle

52 Scopus citations

Specific inhibition of AQP1 water channels in isolated rat intrahepatic bile duct units by small interfering RNAs

Splinter, P. L., Masyuk, A. I. & La Russo, N. F., Feb 21 2003, In : Journal of Biological Chemistry. 278, 8, p. 6268-6274 7 p.

Research output: Contribution to journalArticle

54 Scopus citations

Strategies for improving attendance at medical grand rounds at an Academic Medical Center

Mueller, P., Litin, S. C., Sowden, M. L., Habermann, T. M. & La Russo, N. F., May 1 2003, In : Mayo Clinic Proceedings. 78, 5, p. 549-553 5 p.

Research output: Contribution to journalArticle

21 Scopus citations

The "age" factor in adult medicine

Tefferi, A. & La Russo, N. F., Jul 1 2003, In : Mayo Clinic Proceedings. 78, 7, p. 913 1 p.

Research output: Contribution to journalArticle

4 Scopus citations

Water Transporting Properties of Hepatocyte Basolateral and Canalicular Plasma Membrane Domains

Marinelli, R. A., Tietz, P. S., Caride, A. J., Huang, B. Q. & La Russo, N. F., Oct 31 2003, In : Journal of Biological Chemistry. 278, 44, p. 43157-43162 6 p.

Research output: Contribution to journalArticle

58 Scopus citations
2002

A learner-centered academic career development curriculum.

McDonald, F. S., Schultz, H. J. & La Russo, N. F., May 2002, In : Academic medicine : journal of the Association of American Medical Colleges. 77, 5, p. 463 1 p.

Research output: Contribution to journalArticle

3 Scopus citations

A novel incentive system for faculty in an academic medical center

Brandt, T. L., Romme, C. R., La Russo, N. F. & Lindor, K. D., Nov 5 2002, In : Annals of Internal Medicine. 137, 9, p. 738-743 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Channel-mediated water movement across enclosed or perfused mouse intrahepatic bile duct units

Gong, A. Y., Masyuk, A. I., Splinter, P. L., Huebert, R. C., Tietz, P. S. & La Russo, N. F., 2002, In : American Journal of Physiology - Cell Physiology. 283, 1 52-1

Research output: Contribution to journalArticle

19 Scopus citations

Cholangiocyte biology

Tietz, P. & La Russo, N. F., 2002, In : Current Opinion in Gastroenterology. 18, 3, p. 360-365 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Cryptosporidiosis

Chen, X. M., Keithly, J. S., Paya, C. V. & La Russo, N. F., May 30 2002, In : New England Journal of Medicine. 346, 22, p. 1723-1731 9 p.

Research output: Contribution to journalArticle

342 Scopus citations

Cryptosporidiosis and the pathogenesis of AIDS-cholangiopathy

Chen, X. M. & La Russo, N. F., Aug 2002, In : Seminars in Liver Disease. 22, 3, p. 277-289 13 p.

Research output: Contribution to journalArticle

41 Scopus citations

Experimental models to study cholangiocyte biology

Tietz, P. S., Chen, X. M., Gong, A. Y., Huebert, R. C., Masyuk, A., Masyuk, T., Splinter, P. L. & La Russo, N. F., 2002, In : World Journal of Gastroenterology. 8, 1, p. 1-4 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Expression and localization of aquaporin water channels in rat hepatocytes. Evidence for a role in canalicular bile secretion

Huebert, R. C., Splinter, P. L., Garcia, F., Marinelli, R. A. & La Russo, N. F., Jun 21 2002, In : Journal of Biological Chemistry. 277, 25, p. 22710-22717 8 p.

Research output: Contribution to journalArticle

121 Scopus citations
3 Scopus citations

In primary sclerosing cholangitis, gallbladder polyps are frequently malignant

Buckles, D. C., Lindor, K. D., La Russo, N. F., Petrovic, L. M. & Gores, G. J., 2002, In : American Journal of Gastroenterology. 97, 5, p. 1138-1142 5 p.

Research output: Contribution to journalArticle

132 Scopus citations

Intrahepatic bile ducts transport water in response to absorbed glucose

Masyuk, A. I., Masyuk, T. V., Tietz, P. S., Splinter, P. L. & La Russo, N. F., Sep 2002, In : American Journal of Physiology - Cell Physiology. 283, 3 52-3

Research output: Contribution to journalArticle

35 Scopus citations

Optimization of a research web environment for academic internal medicine faculty

Elkin, P. L., Sorensen, B., De Palo, D., Poland, G., Bailey, K. R., Wood, D. L. & La Russo, N. F., Sep 2002, In : Journal of the American Medical Informatics Association. 9, 5, p. 472-478 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Pirfenidone in the treatment of primary sclerosing cholangitis

Angulo, P., MacCarty, R. L., Sylvestre, P. B., Jorgensen, R. A., Wiesner, R. H., La Russo, N. F. & Lindor, K. D., 2002, In : Digestive Diseases and Sciences. 47, 1, p. 157-161 5 p.

Research output: Contribution to journalArticle

49 Scopus citations

Regulation of Ca2+ signaling in rat bile duct epithelia by inositol 1,4,5-trisphosphate receptor isoforms

Hirata, K., Dufour, J. F., Shibao, K., Knickelbein, R., O'Neill, A. F., Bode, H. P., Cassio, D., St-Pierre, M. V., La Russo, N. F., Leite, M. F. & Nathanson, M. H., 2002, In : Hepatology. 36, 2, p. 284-296 13 p.

Research output: Contribution to journalArticle

59 Scopus citations

The pathobiology of biliary epithelia

Alpini, G., McGill, J. M. & La Russo, N. F., 2002, In : Hepatology. 35, 5, p. 1256-1268 13 p.

Research output: Contribution to journalArticle

114 Scopus citations

Water transport by epithelia of the digestive tract

Masyuk, A. I., Marinelli, R. A. & La Russo, N. F., 2002, In : Gastroenterology. 122, 2, p. 545-562 18 p.

Research output: Contribution to journalArticle

96 Scopus citations
2001

Bcl-2-dependent oxidation of pyruvate dehydrogenase-E2, a primary biliary cirrhosis autoantigen, during apoptosis

Odin, J. A., Huebert, R. C., Casciola-Rosen, L., La Russo, N. F. & Rosen, A., 2001, In : Journal of Clinical Investigation. 108, 2, p. 223-232 10 p.

Research output: Contribution to journalArticle

176 Scopus citations

Cryptosporidium parvum activates nuclear factor κB in biliary epithelia preventing epithelial cell apoptosis

Chen, X. M., Levine, S. A., Splinter, P. L., Tietz, P. S., Ganong, A. L., Jobin, C., Gores, G. J., Paya, C. V. & La Russo, N. F., 2001, In : Gastroenterology. 120, 7, p. 1774-1783 10 p.

Research output: Contribution to journalArticle

94 Scopus citations

Erratum: Human Oggl, a protein involved in the repair of 8-oxoguanine, is inhibited by nitric oxide (Cancer Research (September 1, 2001) (6388-6393))

Jaiswal, M., La Russo, N. F., Nishioka, K., Nakabeppu, Y. & Gores, G. J., Oct 15 2001, In : Cancer Research. 61, 20, p. 7705 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

High-dose ursodeoxycholic acid as a therapy for patients with primary sclerosing cholangitis

Harnois, D., Angulo, P., Jorgensen, R. A., La Russo, N. F. & Lindor, K. D., May 2001, In : American Journal of Gastroenterology. 96, 5, p. 1558-1562 5 p.

Research output: Contribution to journalArticle

197 Scopus citations

Human Ogg1, a protein involved in the repair of 8-oxoguanine, is inhibited by nitric oxide

Jaiswal, M., La Russo, N. F., Nishioka, N., Nakabeppu, Y. & Gores, G. J., Aug 1 2001, In : Cancer Research. 61, 17, p. 6388-6393 6 p.

Research output: Contribution to journalArticle

154 Scopus citations
232 Scopus citations

Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes

Jaiswal, M., La Russo, N. F., Shapiro, R. A., Billiar, T. R. & Gores, G. J., 2001, In : Gastroenterology. 120, 1, p. 190-199 10 p.

Research output: Contribution to journalArticle

152 Scopus citations

Polarized expression and function of P2Y ATP receptors in rat bile duct epithelia

Dranoff, J. A., Masyuk, A. I., Kruglov, E. A., La Russo, N. F. & Nathanson, M. H., 2001, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 281, 4 44-4

Research output: Contribution to journalArticle

83 Scopus citations

Quantitative assessment of the rat intrahepatic biliary system by three-dimensional reconstruction

Masyuk, T. V., Ritman, E. L. & La Russo, N. F., 2001, In : American Journal of Pathology. 158, 6, p. 2079-2088 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

Stimulation of ATP secretion in the liver by therapeutic bile acids

Nathanson, M. H., Burgstahler, A. D., Masyuk, A. & La Russo, N. F., Aug 15 2001, In : Biochemical Journal. 358, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

62 Scopus citations

The Water Channel Aquaporin-8 is Mainly Intracellular in Rat Hepatocytes, and its Plasma Membrane Insertion is Stimulated by Cyclic AMP

García, F., Kierbel, A., Larocca, M. C., Gradilone, S. A., Splinter, P., La Russo, N. F. & Marinelli, R. A., Apr 13 2001, In : Journal of Biological Chemistry. 276, 15, p. 12147-12152 6 p.

Research output: Contribution to journalArticle

171 Scopus citations

Upregulation of secretin receptors on cholangiocytes after bile duct ligation

Tietz, P. S., Hadac, E. M., Miller, L. J. & La Russo, N. F., Feb 2 2001, In : Regulatory Peptides. 97, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Water movement across rat bile duct units is transcellular and channel-mediated

Cova, E., Gong, A. Y., Marinelli, R. A. & La Russo, N. F., 2001, In : Hepatology. 34, 3, p. 456-463 8 p.

Research output: Contribution to journalArticle

31 Scopus citations
2000

Academic internal medicine: challenges and opportunities - Part II

Costa, S. T., Brater, D. C., Coughlin, J. R., Danoff, D., Goode, L. D., Hazzard, W. R., La Russo, N. F., Matherlee, K. R., Spurrier, B. R. & Stolp-Smith, S. C., 2000, In : American Journal of Medicine. 108, 7, p. 601-608 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
98 Scopus citations