• 4742 Citations
  • 40 Scopus h-Index
19952020

Research output per year

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Research Output

2020

Author Correction: Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer (Nature Medicine, (2019), 25, 4, (628-640), 10.1038/s41591-019-0368-8)

Bryant, K. L., Stalnecker, C. A., Zeitouni, D., Klomp, J. E., Peng, S., Tikunov, A. P., Gunda, V., Pierobon, M., Waters, A. M., George, S. D., Tomar, G., Papke, B., Hobbs, G. A., Yan, L., Hayes, T. K., Diehl, J. N., Goode, G. D., Chaika, N. V., Wang, Y., Zhang, G. F. & 11 others, Witkiewicz, A. K., Knudsen, E. S., Petricoin, E. F., Singh, P. K., Macdonald, J. M., Tran, N. L., Lyssiotis, C. A., Ying, H., Kimmelman, A. C., Cox, A. D. & Der, C. J., Jun 1 2020, In : Nature Medicine. 26, 6, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Decreased nonspecific adhesivity, receptor-targeted therapeutic nanoparticles for primary and metastatic breast cancer

Dancy, J. G., Wadajkar, A. S., Connolly, N. P., Galisteo, R., Ames, H. M., Peng, S., Tran, N. L., Goloubeva, O. G., Woodworth, G. F., Winkles, J. A. & Kim, A. J., 2020, In : Science Advances. 6, 3, eaax3931.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Genomic and phenotypic characterization of a broad panel of patient-derived xenografts reflects the diversity of glioblastoma

Vaubel, R. A., Tian, S., Remonde, D., Schroeder, M. A., Mladek, A. C., Kitange, G. J., Caron, A., Kollmeyer, T. M., Grove, R., Peng, S., Carlson, B. L., Ma, D. J., Sarkar, G., Evers, L., Decker, P. A., Yan, H., Dhruv, H. D., Berens, M. E., Wang, Q., Marin, B. M. & 14 others, Klee, E. W., Califano, A., LaChance, D. H., Eckel-Passow, J. E., Verhaak, R. G., Sulman, E. P., Burns, T. C., Meyer, F. B., O'Neill, B. P., Tran, N. L., Giannini, C., Jenkins, R. B., Parney, I. F. & Sarkaria, J. N., Mar 1 2020, In : Clinical Cancer Research. 26, 5, p. 1094-1104 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Localized metabolomic gradients in patient-derived xenograft models of glioblastoma

Randall, E. C., Lopez, B. G. C., Peng, S., Regan, M. S., Abdelmoula, W. M., Basu, S. S., Santagata, S., Yoon, H., Haigis, M. C., Agar, J. N., Tran, N. L., Elmquist, W. F., White, F. M., Sarkaria, J. N. & Agar, N. Y. R., Mar 15 2020, In : Cancer research. 80, 6, p. 1258-1267 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers

Ozkan-Dagliyan, I., Diehl, J. N., George, S. D., Schaefer, A., Papke, B., Klotz-Noack, K., Waters, A. M., Goodwin, C. M., Gautam, P., Pierobon, M., Peng, S., Gilbert, T. S. K., Lin, K. H., Dagliyan, O., Wennerberg, K., Petricoin, E. F., Tran, N. L., Bhagwat, S. V., Tiu, R. V., Peng, S. B. & 6 others, Herring, L. E., Graves, L. M., Sers, C., Wood, K. C., Cox, A. D. & Der, C. J., Jun 16 2020, In : Cell reports. 31, 11, 107764.

Research output: Contribution to journalArticle

Open Access
2019

Accurate patient-specific machine learning models of glioblastoma invasion using transfer learning

Hu, L. S., Yoon, H., Eschbacher, J. M., Baxter, L. C., Dueck, A. C., Nespodzany, A., Smith, K. A., Nakaji, P., Xu, Y., Wang, L., Karis, J. P., Hawkins-Daarud, A. J., Singleton, K. W., Jackson, P. R., Anderies, B. J., Bendok, B. R., Zimmerman, R. S., Quarles, C., Porter-Umphrey, A. B., Mrugala, M. M. & 11 others, Sharma, A., Hoxworth, J., Sattur, M. G., Sanai, N., Koulemberis, P. E., Krishna, C., Mitchell, J. R., Wu, T., Tran, N. L., Swanson, K. R. & Li, J., Jan 1 2019, In : American Journal of Neuroradiology. 40, 3, p. 418-425 8 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

Bryant, K. L., Stalnecker, C. A., Zeitouni, D., Klomp, J. E., Peng, S., Tikunov, A. P., Gunda, V., Pierobon, M., Waters, A. M., George, S. D., Tomar, G., Papke, B., Hobbs, G. A., Yan, L., Hayes, T. K., Diehl, J. N., Goode, G. D., Chaika, N. V., Wang, Y., Zhang, G. F. & 11 others, Witkiewicz, A. K., Knudsen, E. S., Petricoin, E. F., Singh, P. K., Macdonald, J. M., Tran, N. L., Lyssiotis, C. A., Ying, H., Kimmelman, A. C., Cox, A. D. & Der, C. J., Apr 1 2019, In : Nature Medicine. 25, 4, p. 628-640 13 p.

Research output: Contribution to journalArticle

70 Scopus citations

Germline predisposition and copy number alteration in pre-stage lung adenocarcinomas presenting as ground-glass nodules

Ren, Y., Huang, S., Dai, C., Xie, D., Zheng, L., Xie, H., Zheng, H., She, Y., Zhou, F., Wang, Y., Li, P., Fei, K., Jiang, G., Zhang, Y., Su, B., Alejandro Sweet-Cordero, E., Tran, N. L., Yang, Y., Patel, J. N., Rolfo, C. & 7 others, Rocco, G., Cardona, A. F., Tuzi, A., Suter, M. B., Yang, P., Xu, W. & Chen, C., 2019, In : Frontiers in Oncology. 9, MAR, 288.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Inhibition of phosphatidylinositol 3-kinase by PX-866 suppresses temozolomide-induced autophagy and promotes apoptosis in glioblastoma cells

Harder, B. G., Peng, S., Sereduk, C. P., Sodoma, A. M., Kitange, G. J., Loftus, J. C., Sarkaria, J. N. & Tran, N. L., Nov 14 2019, In : Molecular Medicine. 25, 1, 49.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Leveraging spatial variation in tumor purity for improved somatic variant calling of archival tumor only samples

Halperin, R. F., Liang, W. S., Kulkarni, S., Tassone, E. E., Adkins, J., Enriquez, D., Tran, N. L., Hank, N. C., Newell, J., Kodira, C., Korn, R., Berens, M. E., Kim, S. & Byron, S. A., 2019, In : Frontiers in Oncology. 9, MAR

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

MetaMarker: A pipeline for de novo discovery of novel metagenomic biomarkers

Koohi-Moghadam, M., Borad, M. J., Tran, N. L., Swanson, K. R., Boardman, L. A., Sun, H. & Wang, J., Oct 1 2019, In : Bioinformatics. 35, 19, p. 3812-3814 3 p.

Research output: Contribution to journalArticle

2018

A Novel Signaling Complex between TROY and EGFR Mediates Glioblastoma Cell Invasion

Ding, Z., Roos, A., Kloss, J., Dhruv, H., Peng, S., Pirrotte, P., Eschbacher, J. M., Tran, N. & Loftus, J. C., Feb 1 2018, In : Molecular Cancer Research. 16, 2, p. 322-332 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Differential expression of the TWEAK receptor Fn14 in IDH1 wild-type and mutant gliomas

Hersh, D. S., Peng, S., Dancy, J. G., Galisteo, R., Eschbacher, J. M., Castellani, R. J., Heath, J. E., Legesse, T., Kim, A. J., Woodworth, G. F., Tran, N. L. & Winkles, J. A., Jun 1 2018, In : Journal of neuro-oncology. 138, 2, p. 241-250 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

EGFRvIII–Stat5 signaling enhances glioblastoma cell migration and survival

Roos, A., Dhruv, H. D., Peng, S., Inge, L. J., Tuncali, S., Pineda, M., Millard, N., Mayo, Z., Eschbacher, J. M., Loftus, J. C., Winkles, J. A. & Tran, N., Jul 1 2018, In : Molecular Cancer Research. 16, 7, p. 1185-1195 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Evaluation of pre-analytical factors affecting plasma DNA analysis

Markus, H., Contente-Cuomo, T., Farooq, M., Liang, W. S., Borad, M. J., Sivakumar, S., Gollins, S., Tran, N. L., Dhruv, H. D., Berens, M. E., Bryce, A., Sekulic, A., Ribas, A., Trent, J. M., Lorusso, P. M. & Murtaza, M., Dec 1 2018, In : Scientific reports. 8, 1, 7375.

Research output: Contribution to journalArticle

29 Scopus citations

Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma

Randall, E. C., Emdal, K. B., Laramy, J. K., Kim, M., Roos, A., Calligaris, D., Regan, M. S., Gupta, S. K., Mladek, A. C., Carlson, B. L., Johnson, A. J., Lu, F. K., Xie, X. S., Joughin, B. A., Reddy, R. J., Peng, S., Abdelmoula, W. M., Jackson, P. R., Kolluri, A., Kellersberger, K. A. & 8 others, Agar, J. N., Lauffenburger, D. A., Swanson, K. R., Tran, N. L., Elmquist, W. F., White, F. M., Sarkaria, J. N. & Agar, N. Y. R., Dec 1 2018, In : Nature communications. 9, 1, 4904.

Research output: Contribution to journalArticle

13 Scopus citations

PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival

Ding, Z., Dhruv, H., Kwiatkowska-Piwowarczyk, A., Ruggieri, R., Kloss, J., Symons, M., Pirrotte, P., Eschbacher, J. M., Tran, N. & Loftus, J. C., Oct 1 2018, In : Neoplasia (United States). 20, 10, p. 1045-1058 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Prospective Feasibility Trial for Genomics-Informed Treatment in Recurrent and Progressive Glioblastoma

Byron, S. A., Tran, N., Halperin, R. F., Phillips, J. J., Kuhn, J. G., De Groot, J. F., Colman, H., Ligon, K. L., Wen, P. Y., Cloughesy, T. F., Mellinghoff, I. K., Butowski, N. A., Taylor, J. W., Clarke, J. L., Chang, S. M., Berger, M. S., Molinaro, A. M., Maggiora, G. M., Peng, S., Nasser, S. & 6 others, Liang, W. S., Trent, J. M., Berens, M. E., Carpten, J. D., Craig, D. W. & Prados, M. D., Jan 15 2018, In : Clinical Cancer Research. 24, 2, p. 295-305 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

The TNF receptor family member Fn14 is highly expressed in recurrent glioblastoma and in GBM patient-derived xenografts with acquired temozolomide resistance

Hersh, D. S., Harder, B. G., Roos, A., Peng, S., Heath, J. E., Legesse, T., Kim, A. J., Woodworth, G. F., Tran, N. L. & Winkles, J. A., 2018, In : Neuro-oncology. 20, 10, p. 1321-1330 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
2017

Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells

Roos, A., Dhruv, H. D., Mathews, I. T., Inge, L. J., Tuncali, S., Hartman, L. K., Chow, D., Millard, N., Yin, H. H., Kloss, J., Loftus, J. C., Winkles, J. A., Berens, M. E. & Tran, N. L., 2017, In : Oncotarget. 8, 7, p. 12234-12246 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Integrated genomic analysis of survival outliers in glioblastoma

Peng, S., Dhruv, H., Armstrong, B., Salhia, B., Legendre, C., Kiefer, J., Parks, J., Virk, S., Sloan, A. E., Ostrom, Q. T., Barnholtz-Sloan, J. S., Tran, N. & Berens, M. E., 2017, In : Neuro-Oncology. 19, 6, p. 833-844 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Molecular and microenvironmental determinants of glioma stem-like cell survival and invasion

Roos, A., Ding, Z., Loftus, J. C. & Tran, N. L., Jun 16 2017, In : Frontiers in Oncology. 7, JUN, 120.

Research output: Contribution to journalReview article

48 Scopus citations

MTCTScan: A comprehensive platform for annotation and prioritization of mutations affecting drug sensitivity in cancers

Li, M. J., Yao, H., Huang, D., Liu, H., Liu, Z., Xu, H., Qin, Y., Prinz, J., Xia, W., Wang, P., Yan, B., Tran, N., Kocher, J-P., Sham, P. C. & Wang, J., Jul 3 2017, In : Nucleic Acids Research. 45, W1, p. W215-W221

Research output: Contribution to journalArticle

2 Scopus citations

Radiogenomics to characterize regional genetic heterogeneity in glioblastoma

Hu, L. S., Ning, S., Eschbacher, J. M., Baxter, L. C., Gaw, N., Ranjbar, S., Plasencia, J., Dueck, A., Peng, S., Smith, K. A., Nakaji, P., Karis, J. P., Quarles, C. C., Wu, T., Loftus, J. C., Jenkins, R. B., Sicotte, H., Kollmeyer, T. M., O'Neill, B. P., Elmquist, W. & 7 others, Hoxworth, J. M., Frakes, D., Sarkaria, J. N., Swanson, K., Tran, N., Li, J. & Mitchell, J. R., 2017, In : Neuro-Oncology. 19, 1, p. 128-137 10 p.

Research output: Contribution to journalArticle

66 Scopus citations

RNA sequencing and transcriptome arrays analyses show opposing results for alternative splicing in patient derived samples

Nazarov, P. V., Muller, A., Kaoma, T., Nicot, N., Maximo, C., Birembaut, P., Tran, N. L., Dittmar, G. & Vallar, L., Jun 6 2017, In : BMC genomics. 18, 1, 443.

Research output: Contribution to journalArticle

30 Scopus citations
2016

Pharmacological Inhibition of the Protein Kinase MRK/ZAK Radiosensitizes Medulloblastoma

Markowitz, D., Powell, C., Tran, N. L., Berens, M. E., Ryken, T. C., Vanan, M., Rosen, L., He, M., Sun, S., Symons, M., Al-Abed, Y. & Ruggieri, R., Aug 2016, In : Molecular cancer therapeutics. 15, 8, p. 1799-1808 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Propentofylline inhibits glioblastoma cell invasion and survival by targeting the TROY signaling pathway

Dhruv, H. D., Roos, A., Tomboc, P. J., Tuncali, S., Chavez, A., Mathews, I., Berens, M. E., Loftus, J. C. & Tran, N. L., Feb 1 2016, In : Journal of neuro-oncology. 126, 3, p. 397-404 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

SGEF is regulated via TWEAK/Fn14/NF-κB signaling and promotes survival by modulation of the DNA repair response to temozolomide

Fortin Ensign, S. P., Roos, A., Mathews, I. T., Dhruv, H. D., Tuncali, S., Sarkaria, J. N., Symons, M. H., Loftus, J. C., Berens, M. E. & Tran, N. L., Mar 2016, In : Molecular Cancer Research. 14, 3, p. 302-312 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

The TWEAK receptor Fn14 is a potential cell surface portal for targeted delivery of glioblastoma therapeutics

Perez, J. G., Tran, N., Rosenblum, M. G., Schneider, C. S., Connolly, N. P., Kim, A. J., Woodworth, G. F. & Winkles, J. A., Apr 28 2016, In : Oncogene. 35, 17, p. 2145-2155 11 p.

Research output: Contribution to journalReview article

28 Scopus citations

Tumor-targeted nanotherapeutics: Overcoming treatment barriers for glioblastoma

Wadajkar, A. S., Dancy, J. G., Hersh, D. S., Anastasiadis, P., Tran, N., Woodworth, G. F., Winkles, J. A. & Kim, A. J., 2016, (Accepted/In press) In : Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology.

Research output: Contribution to journalArticle

22 Scopus citations
2015

Multi-parametric MRI and texture analysis to visualize spatial histologic heterogeneity and tumor extent in glioblastoma

Hu, L. S., Ning, S., Eschbacher, J. M., Gaw, N., Dueck, A. C., Smith, K. A., Nakaji, P., Plasencia, J., Ranjbar, S., Price, S. J., Tran, N., Loftus, J., Jenkins, R., O'Neill, B. P., Elmquist, W., Baxter, L. C., Gao, F., Frakes, D., Karis, J. P., Zwart, C. & 5 others, Swanson, K. R., Sarkaria, J., Wu, T., Mitchell, J. R. & Li, J., Nov 1 2015, In : PloS one. 10, 11, e0141506.

Research output: Contribution to journalArticle

53 Scopus citations

Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein

Salanti, A., Clausen, T. M., Agerbæk, M. O., Al Nakouzi, N., Dahlbäck, M., Oo, H. Z., Lee, S., Gustavsson, T., Rich, J. R., Hedberg, B. J., Mao, Y., Barington, L., Pereira, M. A., LoBello, J., Endo, M., Fazli, L., Soden, J., Wang, C. K., Sander, A. F., Dagil, R. & 15 others, Thrane, S., Holst, P. J., Meng, L., Favero, F., Weiss, G. J., Nielsen, M. A., Freeth, J., Nielsen, T. O., Zaia, J., Tran, N., Trent, J., Babcook, J. S., Theander, T. G., Sorensen, P. H. & Daugaard, M., Oct 12 2015, In : Cancer Cell. 28, 4, p. 500-514 15 p., 2143.

Research output: Contribution to journalArticle

71 Scopus citations

The TWEAK receptor Fn14 is an Src-inducible protein and a positive regulator of Src-driven cell invasion

Cheng, E., Whitsett, T. G., Tran, N. L. & Winkles, J. A., Mar 1 2015, In : Molecular Cancer Research. 13, 3, p. 575-583 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Toward precision medicine in glioblastoma: The promise and the challenges

Prados, M. D., Byron, S. A., Tran, N. L., Phillips, J. J., Molinaro, A. M., Ligon, K. L., Wen, P. Y., Kuhn, J. G., Mellinghoff, I. K., De Groot, J. F., Colman, H., Cloughesy, T. F., Chang, S. M., Ryken, T. C., Tembe, W. D., Kiefer, J. A., Berens, M. E., Craig, D. W., Carpten, J. D. & Trent, J. M., 2015, In : Neuro-oncology. 17, 8, p. 1051-1063 13 p.

Research output: Contribution to journalReview article

103 Scopus citations
2014

Current approaches to the treatment of metastatic brain tumours

Owonikoko, T. K., Arbiser, J., Zelnak, A., Shu, H. K. G., Shim, H., Robin, A. M., Kalkanis, S. N., Whitsett, T. G., Salhia, B., Tran, N. L., Ryken, T., Moore, M. K., Egan, K. M. & Olson, J. J., Apr 25 2014, In : Nature Reviews Clinical Oncology. 11, 4, p. 203-222 20 p.

Research output: Contribution to journalReview article

134 Scopus citations

Development of human serine protease-based therapeutics targeting Fn14 and identification of Fn14 as a new target overexpressed in TNBC

Zhou, H., Mohamedali, K. A., Gonzalez-Angulo, A. M., Cao, Y., Migliorini, M., Cheung, L. H., LoBello, J., Lei, X., Qi, Y., Hittelman, W. N., Winkles, J. A., Tran, N. L. & Rosenblum, M. G., Nov 1 2014, In : Molecular cancer therapeutics. 13, 11, p. 2688-2705 18 p.

Research output: Contribution to journalArticle

11 Scopus citations

FN14 expression correlates with MET in NSCLC and promotes MET-driven cell invasion

Whitsett, T. G., Fortin Ensign, S. P., Dhruv, H. D., Inge, L. J., Kurywchak, P., Wolf, K. K., LoBello, J., Kingsley, C. B., Allen, J. W., Weiss, G. J. & Tran, N. L., Aug 2014, In : Clinical and Experimental Metastasis. 31, 6, p. 613-623 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

Guanine nucleotide exchange factor Dock7 mediates HGF-induced glioblastoma cell invasion via Rac activation

Murray, D. W., Didier, S., Chan, A., Paulino, V., Van Aelst, L., Ruggieri, R., Tran, N. L., Byrne, A. T. & Symons, M., Mar 4 2014, In : British journal of cancer. 110, 5, p. 1307-1315 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Integrated genomic and epigenomic analysis of breast cancer brain metastasis

Salhia, B., Kiefer, J., Ross, J. T. D., Metapally, R., Martinez, R. A., Johnson, K. N., DiPerna, D. M., Paquette, K. M., Jung, S., Nasser, S., Wallstrom, G., Tembe, W., Baker, A., Carpten, J., Resau, J., Ryken, T., Sibenaller, Z., Petricoin, E. F., Liotta, L. A., Ramanathan, R. K. & 2 others, Berens, M. E. & Tran, N. L., Jan 29 2014, In : PloS one. 9, 1, e85448.

Research output: Contribution to journalArticle

61 Scopus citations

LKB1 inactivation sensitizes non-small cell lung cancer to pharmacological aggravation of ER stress

Inge, L. J., Friel, J. M., Richer, A. L., Fowler, A. J., Whitsett, T., Smith, M. A., Tran, N. L. & Bremner, R. M., Oct 1 2014, In : Cancer Letters. 352, 2, p. 187-195 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Mcl-1 mediates TWEAK/Fn14-induced non-small cell lung cancer survival and therapeutic response

Whitsett, T. G., Mathews, I. T., Cardone, M. H., Lena, R. J., Pierceall, W. E., Bittner, M., Sima, C., LoBello, J., Weiss, G. J. & Tran, N. L., Apr 2014, In : Molecular Cancer Research. 12, 4, p. 550-559 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Rho GTPases and their activators, guanine nucleotide exchange factors (GEFs): Their roles in glioma cell invasion

Hu, B., Symons, M., Salhia, B., Fortin, S. P., Tran, N. L., Rutka, J. & Cheng, S. Y., Jan 1 2014, Signaling Pathways and Molecular Mediators in Metastasis. Springer Netherlands, p. 143-169 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) promotes glioblastoma cell chemotaxis via Lyn activation

Dhruv, H. D., Whitsett, T. G., Jameson, N. M., Patel, F., Winkles, J. A., Berens, M. E. & Tran, N. L., Jan 2014, In : Carcinogenesis. 35, 1, p. 218-226 9 p.

Research output: Contribution to journalArticle

10 Scopus citations
2013

An integrated approach to identifying clinically relevant targets in pediatric gliomas

McEachron, T. A., Tomboc, P. & Tran, N. L., Jul 1 2013, In : CNS oncology. 2, 4, p. 303-306 4 p.

Research output: Contribution to journalEditorial

1 Scopus citations
6 Scopus citations

Implications of Rho GTPase signaling in glioma cell invasion and tumor progression

Fortin Ensign, S. P., Mathews, I. T., Symons, M. H., Berens, M. E. & Tran, N. L., 2013, In : Frontiers in Oncology. 3 OCT, Article 241.

Research output: Contribution to journalReview article

63 Scopus citations

IRS1 is highly expressed in localized breast tumors and regulates the sensitivity of breast cancer cells to chemotherapy, while IRS2 is highly expressed in invasive breast tumors

Porter, H. A., Perry, A., Kingsley, C., Tran, N. L. & Keegan, A. D., Sep 28 2013, In : Cancer Letters. 338, 2, p. 239-248 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Molecular determinants of lung cancer metastasis to the central nervous system

Whitsett, T. G., Inge, L. J., Dhruv, H. D., Cheung, P. Y., Weiss, G. J., Bremner, R. M., Winkles, J. A. & Tran, N., 2013, In : Translational Lung Cancer Research. 2, 4, p. 273-283 11 p.

Research output: Contribution to journalReview article

9 Scopus citations

New insights into the functional consequences of ephrin A3 mutations in non-small cell lung cancer

Whitsett, T. G., Loftus, J. C., Winkles, J. A. & Tran, N., 2013, In : Translational Lung Cancer Research. 2, 1, p. 3-5 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Reciprocal Activation of Transcription Factors Underlies the Dichotomy between Proliferation and Invasion of Glioma Cells

Dhruv, H. D., McDonough Winslow, W. S., Armstrong, B., Tuncali, S., Eschbacher, J., Kislin, K., Loftus, J. C., Tran, N. L. & Berens, M. E., Aug 15 2013, In : PloS one. 8, 8, e72134.

Research output: Contribution to journalArticle

30 Scopus citations