Neill R Graff Radford, MD

  • 32870 Citations
  • 95 Scopus h-Index
1981 …2020

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2012

C9ORF72 repeat expansions and other FTD gene mutations in a clinical AD patient series from Mayo Clinic

Wojtas, A., Heggeli, K. A., Finch, N. C., Baker, M., DeJesus-Hernandez, M., Younkin, S. G., Dickson, D. W., Graff Radford, N. R. & Rademakers, R. V., 2012, In : American Journal of Neurodegenerative Diseases. 1, 1, p. 107-118 12 p.

Research output: Contribution to journalArticle

42 Scopus citations
231 Scopus citations

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

Whitcomb, D. C., LaRusch, J., Krasinskas, A. M., Klei, L., Smith, J. P., Brand, R. E., Neoptolemos, J. P., Lerch, M. M., Tector, M., Sandhu, B. S., Guda, N. M., Orlichenko, L., Alkaade, S., Amann, S. T., Anderson, M. A., Baillie, J., Banks, P. A., Conwell, D., Coté, G. A., Cotton, P. B. & 178 others, DiSario, J., Farrer, L. A., Forsmark, C. E., Johnstone, M., Gardner, T. B., Gelrud, A., Greenhalf, W., Haines, J. L., Hartman, D. J., Hawes, R. A., Lawrence, C., Lewis, M., Mayerle, J., Mayeux, R., Melhem, N. M., Money, M. E., Muniraj, T., Papachristou, G. I., Pericak-Vance, M. A., Romagnuolo, J., Schellenberg, G. D., Sherman, S., Simon, P., Singh, V. P., Slivka, A., Stolz, D., Sutton, R., Weiss, F. U., Wilcox, C. M., Zarnescu, N. O., Wisniewski, S. R., O'Connell, M. R., Kienholz, M. L., Roeder, K., Barmada, M. M., Yadav, D., Devlin, B., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Baldwin, C. T., Barber, R., Barnes, L. L., Beach, T. G., Beecham, G. W., Beekly, D., Bennett, D. A., Bigio, E. H., Bird, T. D., Blacker, D., Boxer, A., Burke, J. R., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Cruchaga, C., DeCarli, C., Demirci, F. Y., Dick, M., Dickson, D. W., Duara, R., Ertekin-Taner, N., Faber, K. M., Fallon, K. B., Farlow, M. R., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Goate, A. M., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton-Nelson, K. L., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jicha, G. A., Jin, L. W., Jun, G., Kamboh, M. I., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., Kukul, W. A., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lin, C. F., Lieberman, A. P., Lopez, O. L., Lunetta, K. L., Lyketsos, C. G., MacK, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Murrel, J. R., Naj, A. C., Olichney, J. M., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rosen, H. J., Rosenberg, R. N., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Valladares, O., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsatte, J. P., Wang, L. S., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L., Dec 1 2012, In : Nature Genetics. 44, 12, p. 1349-1354 6 p.

Research output: Contribution to journalArticle

154 Scopus citations

Diagnostic validity of age and education corrections for the mini-mental state examination in older African Americans

Pedraza, O., Clark, J. H., O'Bryant, S. E., Smith, G. E., Ivnik, R. J., Graff-Radford, N. R., Willis, F. B., Petersen, R. C. & Lucas, J. A., Feb 1 2012, In : Journal of the American Geriatrics Society. 60, 2, p. 328-331 4 p.

Research output: Contribution to journalArticle

22 Scopus citations

Evaluation of the role of SNCA variants in survival without neurological disease

Heckman, M. G., Soto-Ortolaza, A. I., Diehl, N. N., Carrasquillo, M. M., Uitti, R. J., Wszolek, Z. K., Graff-Radford, N. R. & Ross, O. A., Aug 13 2012, In : PloS one. 7, 8, e42877.

Research output: Contribution to journalArticle

6 Scopus citations

Evidence for a role of the rare p.A152T variant in mapt in increasing the risk for FTD-spectrum and Alzheimer's diseases

Coppola, G., Chinnathambi, S., Lee, J. J. Y., Dombroski, B. A., Baker, M. C., Soto-ortolaza, A. I., Lee, S. E., Klein, E., Huang, A. Y., Sears, R., Lane, J. R., Karydas, A. M., Kenet, R. O., Biernat, J., Wang, L. S., Cotman, C. W., Decarli, C. S., Levey, A. I., Ringman, J. M., Mendez, M. F. & 210 others, Chui, H. C., Le ber, I., Brice, A., Lupton, M. K., Preza, E., Lovestone, S., Powell, J., Graff-radford, N., Petersen, R. C., Boeve, B. F., Lippa, C. F., Bigio, E. H., Mackenzie, I., Finger, E., Kertesz, A., Caselli, R. J., Gearing, M., Juncos, J. L., Ghetti, B., Spina, S., Bordelon, Y. M., Tourtellotte, W. W., Frosch, M. P., Vonsattel, J. P. G., Zarow, C., Beach, T. G., Albin, R. L., Lieberman, A. P., Lee, V. M., Trojanowski, J. Q., Van deerlin, V. M., Bird, T. D., Galasko, D. R., Masliah, E., White, C. L., Troncoso, J. C., Hannequin, D., Boxer, A. L., Geschwind, M. D., Kumar, S., Mandelkow, E. M., Wszolek, Z. K., Uitti, R. J., Dickson, D. W., Haines, J. L., Mayeux, R., Pericak-vance, M. A., Farrer, L. A., Apostolova, L. G., Arnold, S. E., Baldwin, C. T., Barber, R., Barmada, M. M., Beach, T., Beecham, G. W., Beekly, D., Bennett, D. A., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Buros, J., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cotman, C. W., Crane, P. K., Cruchaga, C., Cummings, J. L., De Jager, P. L., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Diaz-Arrastia, R., Dick, M., Dickson, D. W., Dombroski, B. A., Duara, R., Ellis, W. G., Ertekin-Taner, N. N., Evans, D., Faber, K. M., Fallon, K. B., Farlow, M. R., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Gallins, P. J., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Giordani, B., Glass, J. D., Goate, A. M., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hardy, J., Harrell, L. E., Head, E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Johnson, N., Jun, G., Kamboh, M. I., Karlawish, J., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, P., Kukull, W. A., Lah, J. J., Larson, E. B., Levey, A. I., Lieberman, A. P., Lopez, O. L., Lunetta, K. L., Mack, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Myers, A. J., Naj, A. C., Nowotny, P., Parisi, J. E., Perl, D. P., Peskind, E., Petersen, R. C., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Rajbhandary, R. A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosenberg, R. N., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W., Shelanski, M. L., Slifer, M. A., Smith, C. D., Sonnen, J. A., Spina, S., George-Hyslop, P. S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Wang, L. S., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Younkin, S. G., Ross, O. A., Rademakers, R., Schellenberg, G. D., Miller, B. L., Mandelkow, E. & Geschwind, D. H., Aug 2012, In : Human molecular genetics. 21, 15, p. 3500-3512 13 p.

Research output: Contribution to journalArticle

135 Scopus citations

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus

the Genetic and Environmental Risk for Alzheimer’s Disease (GERAD1) Consortium, the Translational Genomics Research Institute (TGen) Consortium & the European Alzheimer Disease Initiative (EADI), Aug 1 2012, In : Neurobiology of aging. 33, 8, p. 1848.e1-1848.e13

Research output: Contribution to journalArticle

4 Scopus citations

Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory

Barral, S., Bird, T., Goate, A., Farlow, M. R., Diaz-Arrastia, R., Bennett, D. A., Graff-Radford, N., Boeve, B. F., Sweet, R. A., Stern, Y., Wilson, R. S., Foroud, T., Ott, J. & Mayeux, R., May 8 2012, In : Neurology. 78, 19, p. 1464-1471 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

Glutathione S-transferase omega genes in Alzheimer and Parkinson disease risk, age-at-diagnosis and brain gene expression: An association study with mechanistic implications

Allen, M., Zou, F., Chai, H. S., Younkin, C. S., Miles, R., Nair, A. A., Crook, J. E., Pankratz, V. S., Carrasquillo, M. M., Rowley, C. N., Nguyen, T., Ma, L., Malphrus, K. G., Bisceglio, G., Ortolaza, A. I., Palusak, R., Middha, S., Maharjan, S., Georgescu, C., Schultz, D. & 14 others, Rakhshan, F., Kolbert, C. P., Jen, J., Sando, S. B., Aasly, J. O., Barcikowska, M., Uitti, R. J., Wszolek, Z. K., Ross, O. A., Petersen, R. C., Graff-Radford, N. R., Dickson, D. W., Younkin, S. G. & Ertekin-Taner, N., Apr 12 2012, In : Molecular neurodegeneration. 7, 1, 13.

Research output: Contribution to journalArticle

44 Scopus citations

Length of normal alleles of C9ORF72 GGGGCC repeat do not influence disease phenotype

Rutherford, N. J., Heckman, M. G., DeJesus-Hernandez, M., Baker, M. C., Soto-Ortolaza, A. I., Rayaprolu, S., Stewart, H., Finger, E., Volkening, K., Seeley, W. W., Hatanpaa, K. J., Lomen-Hoerth, C., Kertesz, A., Bigio, E. H., Lippa, C., Knopman, D. S., Kretzschmar, H. A., Neumann, M., Caselli, R. J., White, C. L. & 12 others, Mackenzie, I. R., Petersen, R. C., Strong, M. J., Miller, B. L., Boeve, B. F., Uitti, R. J., Boylan, K. B., Wszolek, Z. K., Graff-Radford, N. R., Dickson, D. W., Ross, O. A. & Rademakers, R., Dec 2012, In : Neurobiology of aging. 33, 12, p. 2950.e5-2950.e7

Research output: Contribution to journalArticle

65 Scopus citations

Maternal transmission of alzheimer disease

Heggeli, K. A., Crook, J., Thomas, C. & Graff-Radford, N., Oct 1 2012, In : Alzheimer disease and associated disorders. 26, 4, p. 364-366 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids

Rademakers, R., Baker, M., Nicholson, A. M., Rutherford, N. J., Finch, N., Soto-Ortolaza, A., Lash, J., Wider, C., Wojtas, A., Dejesus-Hernandez, M., Adamson, J., Kouri, N., Sundal, C., Shuster, E. A., Aasly, J., MacKenzie, J., Roeber, S., Kretzschmar, H. A., Boeve, B. F., Knopman, D. S. & 18 others, Petersen, R. C., Cairns, N. J., Ghetti, B., Spina, S., Garbern, J., Tselis, A. C., Uitti, R., Das, P., Van Gerpen, J. A., Meschia, J. F., Levy, S., Broderick, D. F., Graff-Radford, N., Ross, O. A., Miller, B. B., Swerdlow, R. H., Dickson, D. W. & Wszolek, Z. K., Feb 1 2012, In : Nature Genetics. 44, 2, p. 200-205 6 p.

Research output: Contribution to journalArticle

277 Scopus citations

Neuropathologically defined subtypes of Alzheimer's disease differ significantly from neurofibrillary tangle-predominant dementia

Janocko, N. J., Brodersen, K. A., Soto-Ortolaza, A. I., Ross, O. A., Liesinger, A. M., Duara, R., Graff-Radford, N. R., Dickson, D. W. & Murray, M. E., Nov 1 2012, In : Acta neuropathologica. 124, 5, p. 681-692 12 p.

Research output: Contribution to journalArticle

58 Scopus citations

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

Allen, M., Zou, F., Chai, H. S., Younkin, C. S., Crook, J., Shane Pankratz, V., Carrasquillo, M. M., Rowley, C. N., Nair, A. A., Middha, S., Maharjan, S., Nguyen, T., Ma, L., Malphrus, K. G., Palusak, R., Lincoln, S., Bisceglio, G., Georgescu, C., Schultz, D., Rakhshan, F. & 12 others, Kolbert, C. P., Jen, J., Haines, J. L., Mayeux, R., Pericak-Vance, M. A., Farrer, L. A., Schellenberg, G. D., Petersen, R. C., Graff-Radford, N. R., Dickson, D. W., Younkin, S. G. & Ertekin-Taner, N., Jul 17 2012, In : Neurology. 79, 3, p. 221-228 8 p.

Research output: Contribution to journalArticle

91 Scopus citations

Pathogenicity of exonic indels in fused in sarcoma in amyotrophic lateral sclerosis

Rutherford, N. J., Finch, N. A., DeJesus-Hernandez, M., Crook, R. J. P., Lomen-Hoerth, C., Wszolek, Z. K., Uitti, R. J., Graff-Radford, N. R. & Rademakers, R., Feb 2012, In : Neurobiology of aging. 33, 2, p. 424.e23-424.e24

Research output: Contribution to journalArticle

5 Scopus citations

Rare variants in APP, PSEN1 and PSEN2 increase risk for AD in late-onset Alzheimer's disease families

Cruchaga, C., Chakraverty, S., Mayo, K., Vallania, F. L. M., Mitra, R. D., Faber, K., Williamson, J., Bird, T., Diaz-Arrastia, R., Foroud, T. M., Boeve, B. F., Graff-Radford, N. R., St. Jean, P., Lawson, M., Ehm, M. G., Mayeux, R., Goate, A. M. & for the NIA-LOAD - NCRAD Family Study Consortium, T. NIA-LOAD. . NCRAD. F. S. C., Feb 1 2012, In : PloS one. 7, 2, e31039.

Research output: Contribution to journalArticle

172 Scopus citations

Reliable change on the Boston naming test

Sachs, B. C., Lucas, J. A., Smith, G. E., Ivnik, R. J., Petersen, R. C., Graff-Radford, N. R. & Pedraza, O., Mar 1 2012, In : Journal of the International Neuropsychological Society. 18, 2, p. 375-378 4 p.

Research output: Contribution to journalArticle

13 Scopus citations

Telephone-based, cognitive-behavioral therapy for african american dementia caregivers with depression: Initial findings

Glueckauf, R. L., Davis, W. S., Willis, F., Sharma, D., Gustafson, D. J., Hayes, J., Stutzman, M., Proctor, J., Kazmer, M. M., Murray, L., Shipman, J., McIntyre, V., Wesley, L., Schettini, G., Xu, J., Parfitt, F., Graff-Radford, N., Baxter, C., Burnett, K., Noël, L. T. & 2 others, Haire, K. & Springer, J., Dec 1 2012, In : Rehabilitation Psychology. 57, 2, p. 124-139 16 p.

Research output: Contribution to journalArticle

35 Scopus citations
2011

A blood-based screening tool for Alzheimer's disease that spans serum and plasma: Findings from TARC and ADNI

O'Bryant, S. E., Xiao, G., Barber, R., Huebinger, R., Wilhelmsen, K., Edwards, M., Graff-Radford, N., Doody, R. & Diaz-Arrastia, R., Dec 7 2011, In : PloS one. 6, 12, e28092.

Research output: Contribution to journalArticle

101 Scopus citations

Altered microRNA expression in frontotemporal lobar degeneration with TDP-43 pathology caused by progranulin mutations

Kocerha, J., Kouri, N., Baker, M., Finch, N. C., DeJesus-Hernandez, M., Gonzalez, J., Chidamparam, K., Josephs, K. A., Boeve, B. F., Graff-Radford, N. R., Crook, J., Dickson, D. W. & Rademakers, R., Oct 27 2011, In : BMC genomics. 12, 527.

Research output: Contribution to journalArticle

32 Scopus citations

Association of common KIBRA variants with episodic memory and AD risk

Burgess, J. D., Pedraza, O., Graff-Radford, N. R., Hirpa, M., Zou, F., Miles, R., Nguyen, T., Li, M., Lucas, J. A., Ivnik, R. J., Crook, J., Pankratz, V. S., Dickson, D. W., Petersen, R. C., Younkin, S. G. & Ertekin-Taner, N., Mar 2011, In : Neurobiology of aging. 32, 3, p. 557.e1-557.e9

Research output: Contribution to journalArticle

36 Scopus citations

Association of plasma β-amyloid level and cognitive reserve with subsequent cognitive decline

Yaffe, K., Weston, A., Graff-Radford, N. R., Satterfield, S., Simonsick, E. M., Younkin, S. G., Younkin, L. H., Kuller, L., Ayonayon, H. N., Ding, J. & Harris, T. B., Jan 19 2011, In : JAMA - Journal of the American Medical Association. 305, 3, p. 261-266 6 p.

Research output: Contribution to journalArticle

142 Scopus citations

Ataxin-2 repeat-length variation and neurodegeneration

Ross, O. A., Rutherford, N. J., Baker, M., Soto-Ortolaza, A. I., Carrasquillo, M. M., DeJesus-Hernandez, M., Adamson, J., Li, M., Volkening, K., Finger, E., Seeley, W. W., Hatanpaa, K. J., Lomen-Hoerth, C., Kertesz, A., Bigio, E. H., Lippa, C., Woodruff, B. K., Knopman, D. S., White, C. L., Van Gerpen, J. A. & 13 others, Meschia, J. F., Mackenzie, I. R., Boylan, K., Boeve, B. F., Miller, B. L., Strong, M. J., Uitti, R. J., Younkin, S. G., Graff-Radford, N. R., Petersen, R. C., Wszolek, Z. K., Dickson, D. W. & Rademakers, R., Aug 2011, In : Human molecular genetics. 20, 16, p. 3207-3212 6 p.

Research output: Contribution to journalArticle

112 Scopus citations

A yeast functional screen predicts new candidate ALS disease genes

Couthouisa, J., Harta, M. P., Shorter, J., DeJesus-Hernandez, M., Erion, R., Oristano, R., Liu, A. X., Ramos, D., Jethava, N., Hosangadi, D., Epstein, J., Chiang, A., Diaz, Z., Nakaya, T., Ibrahim, F., Kim, H. J., Solski, J. A., Williams, K. L., Mojsilovic-Petrovic, J., Ingre, C. & 21 others, Boylan, K., Graff-Radford, N. R., Dickson, D. W., Clay-Falcone, D., Elman, L., McCluskey, L., Greene, R., Kalb, R. G., Lee, V. M. Y., Trojanowski, J. Q., Ludolph, A., Robberecht, W., Andersen, P. M., Nicholson, G. A., Blair, I. P., King, O. D., Bonini, N. M., Van, V. D., Rademakers, R., Mourelatos, Z. & Gitler, A. D., Dec 27 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 52, p. 20881-20890 10 p.

Research output: Contribution to journalArticle

237 Scopus citations

Clinical and neuropathologic heterogeneity of c9FTD/ALS associated with hexanucleotide repeat expansion in C9ORF72

Murray, M. E., Dejesus-Hernandez, M., Rutherford, N. J., Baker, M., Duara, R., Graff-Radford, N. R., Wszolek, Z. K., Ferman, T. J., Josephs, K. A., Boylan, K. B., Rademakers, R. & Dickson, D. W., Dec 1 2011, In : Acta neuropathologica. 122, 6, p. 673-690 18 p.

Research output: Contribution to journalArticle

212 Scopus citations

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

Hollingworth, P., Harold, D., Sims, R., Gerrish, A., Lambert, J. C., Carrasquillo, M. M., Abraham, R., Hamshere, M. L., Pahwa, J. S., Moskvina, V., Dowzell, K., Jones, N., Stretton, A., Thomas, C., Richards, A., Ivanov, D., Widdowson, C., Chapman, J., Lovestone, S., Powell, J. & 152 others, Proitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Brown, K. S., Passmore, P. A., Craig, D., McGuinness, B., Todd, S., Holmes, C., Mann, D., Smith, A. D., Beaumont, H., Warden, D., Wilcock, G., Love, S., Kehoe, P. G., Hooper, N. M., Vardy, E. R. L. C., Hardy, J., Mead, S., Fox, N. C., Rossor, M., Collinge, J., Maier, W., Jessen, F., Rüther, E., Schürmann, B., Heun, R., Kölsch, H., Van Den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Gallacher, J., Hüll, M., Rujescu, D., Giegling, I., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Sleegers, K., Bettens, K., Engelborghs, S., De Deyn, P. P., Van Broeckhoven, C., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Tsolaki, M., Singleton, A. B., Guerreiro, R., Mühleisen, T. W., Nöthen, M. M., Moebus, S., Jöckel, K. H., Klopp, N., Wichmann, H. E., Pankratz, V. S., Sando, S. B., Aasly, J. O., Barcikowska, M., Wszolek, Z. K., Dickson, D. W., Graff-Radford, N. R., Petersen, R. C., Van Duijn, C. M., Breteler, M. M. B., Ikram, M. A., Destefano, A. L., Fitzpatrick, A. L., Lopez, O., Launer, L. J., Seshadri, S., Berr, C., Campion, D., Epelbaum, J., Dartigues, J. F., Tzourio, C., Alpérovitch, A., Lathrop, M., Feulner, T. M., Friedrich, P., Riehle, C., Krawczak, M., Schreiber, S., Mayhaus, M., Nicolhaus, S., Wagenpfeil, S., Steinberg, S., Stefansson, H., Stefansson, K., SnÆdal, J., Björnsson, S., Jonsson, P. V., Chouraki, V., Genier-Boley, B., Hiltunen, M., Soininen, H., Combarros, O., Zelenika, D., Delepine, M., Bullido, M. J., Pasquier, F., Mateo, I., Frank-Garcia, A., Porcellini, E., Hanon, O., Coto, E., Alvarez, V., Bosco, P., Siciliano, G., Mancuso, M., Panza, F., Solfrizzi, V., Nacmias, B., Sorbi, S., Bossù, P., Piccardi, P., Arosio, B., Annoni, G., Seripa, D., Pilotto, A., Scarpini, E., Galimberti, D., Brice, A., Hannequin, D., Licastro, F., Jones, L., Holmans, P. A., Jonsson, T., Riemenschneider, M., Morgan, K., Younkin, S. G., Owen, M. J., O'Donovan, M., Amouyel, P. & Williams, J., May 2011, In : Nature Genetics. 43, 5, p. 429-436 8 p.

Research output: Contribution to journalArticle

1138 Scopus citations

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

Naj, A. C., Jun, G., Beecham, G. W., Wang, L. S., Vardarajan, B. N., Buros, J., Gallins, P. J., Buxbaum, J. D., Jarvik, G. P., Crane, P. K., Larson, E. B., Bird, T. D., Boeve, B. F., Graff-Radford, N. R., De Jager, P. L., Evans, D., Schneider, J. A., Carrasquillo, M. M., Ertekin-Taner, N., Younkin, S. G. & 135 others, Cruchaga, C., Kauwe, J. S. K., Nowotny, P., Kramer, P., Hardy, J., Huentelman, M. J., Myers, A. J., Barmada, M. M., Demirci, F. Y., Baldwin, C. T., Green, R. C., Rogaeva, E., George-Hyslop, P. S., Arnold, S. E., Barber, R., Beach, T., Bigio, E. H., Bowen, J. D., Boxer, A., Burke, J. R., Cairns, N. J., Carlson, C. S., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cotman, C. W., Cummings, J. L., Decarli, C., Dekosky, S. T., Diaz-Arrastia, R., Dick, M., Dickson, D. W., Ellis, W. G., Faber, K. M., Fallon, K. B., Farlow, M. R., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Giordani, B., Glass, J. D., Growdon, J. H., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jicha, G. A., Jin, L. W., Johnson, N., Karlawish, J., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Lah, J. J., Levey, A. I., Lieberman, A. P., Lopez, O. L., MacK, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Parisi, J. E., Perl, D. P., Peskind, E., Petersen, R. C., Poon, W. W., Quinn, J. F., Rajbhandary, R. A., Raskind, M., Reisberg, B., Ringman, J. M., Roberson, E. D., Rosenberg, R. N., Sano, M., Schneider, L. S., Seeley, W., Shelanski, M. L., Slifer, M. A., Smith, C. D., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Cantwell, L. B., Dombroski, B. A., Beekly, D., Lunetta, K. L., Martin, E. R., Kamboh, M. I., Saykin, A. J., Reiman, E. M., Bennett, D. A., Morris, J. C., Montine, T. J., Goate, A. M., Blacker, D., Tsuang, D. W., Hakonarson, H., Kukull, W. A., Foroud, T. M., Haines, J. L., Mayeux, R., Pericak-Vance, M. A., Farrer, L. A. & Schellenberg, G. D., May 1 2011, In : Nature Genetics. 43, 5, p. 436-443 8 p.

Research output: Contribution to journalArticle

1136 Scopus citations
30 Scopus citations

Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS

DeJesus-Hernandez, M., Mackenzie, I. R., Boeve, B. F., Boxer, A. L., Baker, M., Rutherford, N. J., Nicholson, A. M., Finch, N. C. A., Flynn, H., Adamson, J., Kouri, N., Wojtas, A., Sengdy, P., Hsiung, G. Y. R., Karydas, A., Seeley, W. W., Josephs, K. A., Coppola, G., Geschwind, D. H., Wszolek, Z. K. & 8 others, Feldman, H., Knopman, D. S., Petersen, R. C., Miller, B. L., Dickson, D. W., Boylan, K. B., Graff-Radford, N. R. & Rademakers, R., Oct 20 2011, In : Neuron. 72, 2, p. 245-256 12 p.

Research output: Contribution to journalArticle

2491 Scopus citations

Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration

Chen-Plotkin, A. S., Martinez-Lage, M., Sleiman, P. M. A., Hu, W., Greene, R., Wood, E. M. C., Bing, S., Grossman, M., Schellenberg, G. D., Hatanpaa, K. J., Weiner, M. F., White, C. L., Brooks, W. S., Halliday, G. M., Kril, J. J., Gearing, M., Beach, T. G., Graff-Radford, N. R., Dickson, D. W., Rademakers, R. & 35 others, Boeve, B. F., Pickering-Brown, S. M., Snowden, J., Van Swieten, J. C., Heutink, P., Seelaar, H., Murrell, J. R., Ghetti, B., Spina, S., Grafman, J., Kaye, J. A., Woltjer, R. L., Mesulam, M., Bigio, E., Lladó, A., Miller, B. L., Alzualde, A., Moreno, F., Rohrer, J. D., Mackenzie, I. R. A., Feldman, H. H., Hamilton, R. L., Cruts, M., Engelborghs, S., De Deyn, P. P., Van Broeckhoven, C., Bird, T. D., Cairns, N. J., Goate, A., Frosch, M. P., Riederer, P. F., Bogdanovic, N., Lee, V. M. Y., Trojanowski, J. Q. & Van Deerlin, V. M., Apr 1 2011, In : Archives of neurology. 68, 4, p. 488-497 10 p.

Research output: Contribution to journalArticle

76 Scopus citations

Heritability of different forms of memory in the late onset alzheimer's disease family study

Wilson, R. S., Barral, S., Lee, J. H., Leurgans, S. E., Foroud, T. M., Sweet, R. A., Graff-Radford, N., Bird, T. D., Mayeux, R. & Bennett, D. A., 2011, In : Journal of Alzheimer's Disease. 23, 2, p. 249-255 7 p.

Research output: Contribution to journalArticle

41 Scopus citations
56 Scopus citations

Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

Höglinger, G. U., Melhem, N. M., Dickson, D. W., Sleiman, P. M. A., Wang, L. S., Klei, L., Rademakers, R., De Silva, R., Litvan, I., Riley, D. E., Van Swieten, J. C., Heutink, P., Wszolek, Z. K., Uitti, R. J., Vandrovcova, J., Hurtig, H. I., Gross, R. G., Maetzler, W., Goldwurm, S., Tolosa, E. & 116 others, Borroni, B., Pastor, P., Cantwell, L. B., Han, M. R., Dillman, A., Van Der Brug, M. P., Gibbs, J. R., Cookson, M. R., Hernandez, D. G., Singleton, A. B., Farrer, M. J., Yu, C. E., Golbe, L. I., Revesz, T., Hardy, J., Lees, A. J., Devlin, B., Hakonarson, H., Müller, U., Schellenberg, G. D., Albin, R. L., Alonso, E., Antonini, A., Apfelbacher, M., Arnold, S. E., Avila, J., Beach, T. G., Beecher, S., Berg, D., Bird, T. D., Bogdanovic, N., Boon, A. J. W., Bordelon, Y., Brice, A., Budka, H., Canesi, M., Chiu, W. Z., Cilia, R., Colosimo, C., De Deyn, P. P., De Yebenes, J. G., Kaat, L. D., Duara, R., Durr, A., Engelborghs, S., Fabbrini, G., Finch, N. A., Flook, R., Frosch, M. P., Gaig, C., Galasko, D. R., Gasser, T., Gearing, M., Geller, E. T., Ghetti, B., Graff-Radford, N. R., Grossman, M., Hall, D. A., Hazrati, L. N., Höllerhage, M., Jankovic, J., Juncos, J. L., Karydas, A., Kretzschmar, H. A., Leber, I., Lee, V. M., Lieberman, A. P., Lyons, K. E., Mariani, C., Masliah, E., Massey, L. A., McLean, C. A., Meucci, N., Miller, B. L., Mollenhauer, B., Möller, J. C., Morris, H. R., Morris, C., O'Sullivan, S. S., Oertel, W. H., Ottaviani, D., Padovani, A., Pahwa, R., Pezzoli, G., Pickering-Brown, S., Poewe, W., Rabano, A., Rajput, A., Reich, S. G., Respondek, G., Roeber, S., Rohrer, J. D., Ross, O. A., Rossor, M. N., Sacilotto, G., Seeley, W. W., Seppi, K., Silveira-Moriyama, L., Spina, S., Srulijes, K., St. George-Hyslop, P., Stamelou, M., Standaert, D. G., Tesei, S., Tourtellotte, W. W., Trenkwalder, C., Troakes, C., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Vonsattel, J. P. G., Wenning, G. K., White, C. L., Winter, P., Zarow, C. & Zecchinelli, A. L., Jul 2011, In : Nature Genetics. 43, 7, p. 699-705 7 p.

Research output: Contribution to journalArticle

287 Scopus citations

Inclusion of RBD improves the diagnostic classification of dementia with Lewy bodies

Ferman, T. J., Boeve, B. F., Smith, G. E., Lin, S. C., Silber, M. H., Pedraza, O., Wszolek, Z., Graff-Radford, N. R., Uitti, R., Van Gerpen, J., Pao, W., Knopman, D., Pankratz, V. S., Kantarci, K., Boot, B., Parisi, J. E., Dugger, B. N., Fujishiro, H., Petersen, R. C. & Dickson, D. W., Aug 30 2011, In : Neurology. 77, 9, p. 875-882 8 p.

Research output: Contribution to journalArticle

166 Scopus citations

Investigating statistical epistasis in complex disorders

Turton, J. C., Bullock, J., Medway, C., Shi, H., Brown, K., Belbin, O., Kalsheker, N., Carrasquillo, M. M., Dickson, D. W., Graff-Radford, N. R., Petersen, R. C., Younkin, S. G. & Morgan, K., 2011, In : Journal of Alzheimer's Disease. 25, 4, p. 635-644 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Investigation of 15 of the top candidate genes for late-onset Alzheimer's disease

Belbin, O., Carrasquillo, M. M., Crump, M., Culley, O. J., Hunter, T. A., Ma, L., Bisceglio, G., Zou, F., Allen, M., Dickson, D. W., Graff-Radford, N. R., Petersen, R. C., Morgan, K. & Younkin, S. G., Mar 1 2011, In : Human genetics. 129, 3, p. 273-282 10 p.

Research output: Contribution to journalArticle

45 Scopus citations
71 Scopus citations
370 Scopus citations

Novel p.Ile151Val mutation in VCP in A patient of african american descent with sporadic ALS

DeJesus-Hernandez, M., Desaro, P., Johnston, A., Ross, O. A., Wszolek, Z. K., Ertekin-Taner, N., Graff-Radford, N. R., Rademakers, R. & Boylan, K., Sep 13 2011, In : Neurology. 77, 11, p. 1102-1103 2 p.

Research output: Contribution to journalArticle

36 Scopus citations

Replication of BIN1 association with Alzheimer's disease and evaluation of genetic interactions

Carrasquillo, M. M., Hunter, T. A., Ma, L., Bisceglio, G. D., Zou, F., Crook, J. E., Pankratz, V. S., Sando, S. B., Aasly, J. O., Barcikowska, M., Wszolek, Z. K., Dickson, D. W., Graff-Radford, N. R., Petersen, R. C., Morgan, K. & Younkin, S. G., 2011, In : Journal of Alzheimer's Disease. 24, 4, p. 751-758 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Replication of EPHA1 and CD33 associations with late-onset Alzheimer's disease: A multi-centre case-control study

Carrasquillo, M. M., Belbin, O., Hunter, T. A., Ma, L., Bisceglio, G. D., Zou, F., Crook, J. E., Pankratz, V., Sando, S. B., Aasly, J. O., Barcikowska, M., Wszolek, Z. K., Dickson, D. W., Graff-Radford, N. R., Petersen, R. C., Passmore, P., Morgan, K. & Younkin, S. G., Aug 22 2011, In : Molecular neurodegeneration. 6, 1, 54.

Research output: Contribution to journalArticle

50 Scopus citations

TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers

Finch, N., Carrasquillo, M. M., Baker, M., Rutherford, N. J., Coppola, G., Dejesus-Hernandez, M., Crook, R., Hunter, T., Ghidoni, R., Benussi, L., Crook, J., Finger, E., Hantanpaa, K. J., Karydas, A. M., Sengdy, P., Gonzalez, J., Seeley, W. W., Johnson, N., Beach, T. G., Mesulam, M. & 19 others, Forloni, G., Kertesz, A., Knopman, D. S., Uitti, R., White, C. L., Caselli, R., Lippa, C., Bigio, E. H., Wszolek, Z. K., Binetti, G., MacKenzie, I. R., Miller, B. L., Boeve, B. F., Younkin, S. G., Dickson, D. W., Petersen, R. C., Graff-Radford, N. R., Geschwind, D. H. & Rademakers, R., Feb 1 2011, In : Neurology. 76, 5, p. 467-474 8 p.

Research output: Contribution to journalArticle

132 Scopus citations

Validation of the Mayo Sleep Questionnaire to screen for REM sleep behavior disorder in an aging and dementia cohort

Boeve, B. F., Molano, J. R., Ferman, T. J., Smith, G. E., Lin, S. C., Bieniek, K., Haidar, W., Tippmann-Peikert, M., Knopman, D. S., Graff-Radford, N. R., Lucas, J. A., Petersen, R. C. & Silber, M. H., May 1 2011, In : Sleep Medicine. 12, 5, p. 445-453 9 p.

Research output: Contribution to journalArticle

148 Scopus citations
2010

A computerized technique to assess language use patterns in patients with frontotemporal dementia

Pakhomov, S. V. S., Smith, G. E., Marino, S., Birnbaum, A., Graff-Radford, N., Caselli, R., Boeve, B. & Knopman, D. S., Mar 1 2010, In : Journal of Neurolinguistics. 23, 2, p. 127-144 18 p.

Research output: Contribution to journalArticle

10 Scopus citations

Assessment and familial aggregation of psychosis in Alzheimer's disease from the National institute on aging late onset Alzheimer's disease family study

Sweet, R. A., Bennett, D. A., Graff-Radford, N. R. & Mayeux, R., Apr 1 2010, In : Brain. 133, 4, p. 1155-1162 8 p.

Research output: Contribution to journalArticle

41 Scopus citations

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

Van Deerlin, V. M., Sleiman, P. M. A., Martinez-Lage, M., Chen-Plotkin, A., Wang, L. S., Graff-Radford, N. R., Dickson, D. W., Rademakers, R., Boeve, B. F., Grossman, M., Arnold, S. E., Mann, D. M. A., Pickering-Brown, S. M., Seelaar, H., Heutink, P., Van Swieten, J. C., Murrell, J. R., Ghetti, B., Spina, S., Grafman, J. & 80 others, Hodges, J., Spillantini, M. G., Gilman, S., Lieberman, A. P., Kaye, J. A., Woltjer, R. L., Bigio, E. H., Mesulam, M., Al-Sarraj, S., Troakes, C., Rosenberg, R. N., White, C. L., Ferrer, I., Lladó, A., Neumann, M., Kretzschmar, H. A., Hulette, C. M., Welsh-Bohmer, K. A., Miller, B. L., Alzualde, A., De Munain, A. L., McKee, A. C., Gearing, M., Levey, A. I., Lah, J. J., Hardy, J., Rohrer, J. D., Lashley, T., MacKenzie, I. R. A., Feldman, H. H., Hamilton, R. L., Dekosky, S. T., Van Der Zee, J., Kumar-Singh, S., Van Broeckhoven, C., Mayeux, R., Vonsattel, J. P. G., Troncoso, J. C., Kril, J. J., Kwok, J. B. J., Halliday, G. M., Bird, T. D., Ince, P. G., Shaw, P. J., Cairns, N. J., Morris, J. C., McLean, C. A., Decarli, C., Ellis, W. G., Freeman, S. H., Frosch, M. P., Growdon, J. H., Perl, D. P., Sano, M., Bennett, D. A., Schneider, J. A., Beach, T. G., Reiman, E. M., Woodruff, B. K., Cummings, J., Vinters, H. V., Miller, C. A., Chui, H. C., Alafuzoff, I., Hartikainen, P., Seilhean, D., Galasko, D., Masliah, E., Cotman, C. W., Tũón, M. T., Martínez, M. C. C., Munoz, D. G., Carroll, S. L., Marson, D., Riederer, P. F., Bogdanovic, N., Schellenberg, G. D., Hakonarson, H., Trojanowski, J. Q. & Lee, V. M. Y., Mar 1 2010, In : Nature Genetics. 42, 3, p. 234-239 6 p.

Research output: Contribution to journalArticle

294 Scopus citations

Computerized analysis of speech and language to identify psycholinguistic correlates of frontotemporal lobar degeneration

Pakhomov, S. V. S., Smith, G. E., Chacon, D., Feliciano, Y., Graff-Radford, N., Caselli, R. & Knopman, D. S., Sep 1 2010, In : Cognitive and Behavioral Neurology. 23, 3, p. 165-177 13 p.

Research output: Contribution to journalArticle

31 Scopus citations

Concordant association of Insulin Degrading Enzyme gene (IDE) Variants with IDE mRNA, Aß, and Alzheimer's disease

Carrasquillo, M. M., Belbin, O., Zou, F., Allen, M., Ertekin-Taner, N., Ansari, M., Wilcox, S. L., Kashino, M. R., Ma, L., Younkin, L. H., Younkin, S. G., Younkin, C. S., Dincman, T. A., Howard, M. E., Howell, C. C., Stanton, C. M., Watson, C. M., Crump, M., Vitart, V., Hayward, C. & 25 others, Hastie, N. D., Rudan, I., Campbell, H., Polasek, O., Brown, K., Passmore, P., Craig, D., McGuinness, B., Todd, S., Kehoe, P. G., Mann, D. M., Smith, A. D., Beaumont, H., Warden, D., Holmes, C., Heun, R., Kölsch, H., Kalsheker, N., Pankratz, V. S., Dickson, D. W., Graff-Radford, N. R., Petersen, R. C., Wright, A. F., Younkin, S. G. & Morgan, K., Jan 19 2010, In : PloS one. 5, 1, e8764.

Research output: Contribution to journalArticle

35 Scopus citations

De novo truncating FUS gene mutation as a cause of sporadic amyotrophic lateral sclerosis

DeJesus-Hernandez, M., Kocerha, J., Finch, N., Crook, R., Baker, M., Desaro, P., Johnston, A., Rutherford, N., Wojtas, A., Kennelly, K., Wszolek, Z. K., Graff-Radford, N., Boylan, K. & Rademakers, R., May 1 2010, In : Human mutation. 31, 5, p. E1377-E1389

Research output: Contribution to journalArticle

100 Scopus citations

FUS gene mutations in familial and sporadic amyotrophic lateral sclerosis

Rademakers, R., Stewart, H., Dejesus-Hernandez, M., Krieger, C., Graff-Radford, N., Fabros, M., Briemberg, H., Cashman, N., Eisen, A. & Mackenzie, I. R. A., Aug 1 2010, In : Muscle and Nerve. 42, 2, p. 170-176 7 p.

Research output: Contribution to journalArticle

73 Scopus citations