Neill R Graff Radford, MD

  • 32870 Citations
  • 95 Scopus h-Index
1981 …2020

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2016

Comparing biological markers of Alzheimer's disease across blood fraction and platforms: Comparing apples to oranges

for the ISTAART Blood Based Biomarker Professional Interest Area, Jan 1 2016, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 3, p. 27-34 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Distribution and characteristics of transactive response DNA binding protein 43 kDa pathology in progressive supranuclear palsy

Koga, S., Sanchez-Contreras, M., Josephs, K. A., Uitti, R. J., Graff Radford, N. R., Van Gerpen, J. A., Cheshire, W. P., Wszolek, Z. K., Rademakers, R. V. & Dickson, D. W., 2016, (Accepted/In press) In : Movement Disorders.

Research output: Contribution to journalArticle

23 Scopus citations

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

The Alzheimer's Disease Neuroimaging Initiative, Jun 21 2016, In : Nature communications. 7, 11934.

Research output: Contribution to journalArticle

267 Scopus citations

Evaluating pathogenic dementia variants in posterior cortical atrophy

Carrasquillo, M. M., Barber, I., Lincoln, S. J., Murray, M. E., Camsari, G. B., Khan, Q. U. A., Nguyen, T., Ma, L., Bisceglio, G. D., Crook, J. E., Younkin, S. G., Dickson, D. W., Boeve, B. F., Graff-Radford, N. R., Morgan, K. & Ertekin-Taner, N., Jan 1 2016, In : Neurobiology of aging. 37, p. 38-44 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Expression and processing analyses of wild type and p.R47H TREM2 variant in Alzheimer's disease brains

Ma, L., Allen, M., Sakae, N., Ertekin-Taner, N., Graff-Radford, N. R., Dickson, D. W., Younkin, S. G. & Sevlever, D., Nov 25 2016, In : Molecular neurodegeneration. 11, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

FTDP-17 with Pick body-like inclusions associated with a novel tau mutation, p.E372G

Tacik, P., Deture, M., Carlomagno, Y., Lin, W. L., Murray, M. E., Baker, M. C., Josephs, K. A., Boeve, B. F., Wszolek, Z. K., Graff Radford, N. R., Parisi, J. E., Petrucelli, L., Rademakers, R. V., Isaacson, R. S., Heilman, K. M., Petersen, R. C., Dickson, D. W. & Kouri, N., 2016, (Accepted/In press) In : Brain Pathology.

Research output: Contribution to journalArticle

5 Scopus citations

Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease

Schott, J. M., Crutch, S. J., Carrasquillo, M. M., Uphill, J., Shakespeare, T. J., Ryan, N. S., Yong, K. X., Lehmann, M., Taner, N., Graff Radford, N. R., Boeve, B. F., Murray, M. E., Khan, Q. U. A., Petersen, R. C., Dickson, D. W., Knopman, D. S., Rabinovici, G. D., Miller, B. L., González, A. S., Gil-Néciga, E. & 24 others, Snowden, J. S., Harris, J., Pickering-Brown, S. M., Louwersheimer, E., van der Flier, W. M., Scheltens, P., Pijnenburg, Y. A., Galasko, D., Sarazin, M., Dubois, B., Magnin, E., Galimberti, D., Scarpini, E., Cappa, S. F., Hodges, J. R., Halliday, G. M., Bartley, L., Carrillo, M. C., Bras, J. T., Hardy, J., Rossor, M. N., Collinge, J., Fox, N. C. & Mead, S., Aug 1 2016, In : Alzheimer's and Dementia. 12, 8, p. 862-871 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases

International Parkinson's Disease Genomics Consortium (IPDGC), Oct 13 2016, In : Neurobiology of aging. 38, p. 214.e7-214.e10

Research output: Contribution to journalArticle

37 Scopus citations

Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk

Alzheimer Disease Genetics Consortium, Mar 1 2016, In : Alzheimer's and Dementia. 12, 3, p. 233-243 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases

Allen, M., Carrasquillo, M. M., Funk, C., Heavner, B. D., Zou, F., Younkin, C. S., Burgess, J. D., Chai, H. S., Crook, J., Eddy, J. A., Li, H., Logsdon, B., Peters, M. A., Dang, K. K., Wang, X., Serie, D., Wang, C., Nguyen, T., Lincoln, S., Malphrus, K. & 11 others, Bisceglio, G., Li, M., Golde, T. E., Mangravite, L. M., Asmann, Y., Price, N. D., Petersen, R. C., Graff Radford, N. R., Dickson, D. W., Younkin, S. G. & Taner, N., Oct 11 2016, In : Scientific data. 3, 160089.

Research output: Contribution to journalArticle

45 Scopus citations

Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts Completing the picture

Miller, Z. A., Sturm, V. E., Camsari, G. B., Karydas, A., Yokoyama, J. S., Grinberg, L. T., Boxer, A. L., Rosen, H. J., Rankin, K. P., Tempini, M. L. G., Coppola, G., Geschwind, D. H., Rademakers, R. V., Seeley, W. W., Graff Radford, N. R. & Miller, B. L., 2016, In : Neurology: Neuroimmunology and NeuroInflammation. 3, 6, e301.

Research output: Contribution to journalArticle

28 Scopus citations

LRRK2 variation and dementia with Lewy bodies

Heckman, M. G., Soto-Ortolaza, A. I., Sanchez Contreras, M. Y., Murray, M. E., Pedraza, O. D., Diehl, N. N., Walton, R., Labbé, C., Lorenzo-Betancor, O., Uitti, R. J., Van Gerpen, J. A., Taner, N., Smith, G. E., Kantarci, K. M., Savica, R., Jones, D. T., Graff-Radford, J., Knopman, D. S., Lowe, V., Jack, C. R. J. & 9 others, Petersen, R. C., Parisi, J. E., Rademakers, R. V., Wszolek, Z. K., Graff Radford, N. R., Ferman, T. J., Dickson, D. W., Boeve, B. F. & Ross, O. A., Oct 1 2016, In : Parkinsonism and Related Disorders. 31, p. 98-103 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

MAPT haplotype diversity in multiple system atrophy

Labbé, C., Heckman, M. G., Lorenzo-Betancor, O., Murray, M. E., Ogaki, K., Soto-Ortolaza, A. I., Walton, R. L., Fujioka, S., Koga, S., Uitti, R. J., Van Gerpen, J. A., Petersen, R. C., Graff Radford, N. R., Younkin, S. G., Boeve, B. F., Cheshire, W. P., Low, P. A., Sandroni, P., Coon, E., Singer, W. & 3 others, Wszolek, Z. K., Dickson, D. W. & Ross, O. A., Apr 14 2016, (Accepted/In press) In : Parkinsonism and Related Disorders.

Research output: Contribution to journalArticle

11 Scopus citations

MAPT haplotype H1G is associated with increased risk of dementia with Lewy bodies

Labbé, C., Heckman, M. G., Lorenzo-Betancor, O., Soto-Ortolaza, A. I., Walton, R. L., Murray, M. E., Allen, M., Uitti, R. J., Wszolek, Z. K., Smith, G. E., Kantarci, K. M., Knopman, D. S., Lowe, V., Jack, C. R. J., Taner, N., Hassan, A., Savica, R., Petersen, R. C., Parisi, J. E., Maraganore, D. M. & 5 others, Graff Radford, N. R., Ferman, T. J., Boeve, B. F., Dickson, D. W. & Ross, O. A., 2016, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

16 Scopus citations

Minimal clinically important worsening on the progressive supranuclear Palsy Rating Scale

on behalf of the AL-108-231 Investigators, Oct 1 2016, In : Movement Disorders. 31, 10, p. 1574-1577 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain

Jaeger, P. A., Lucin, K. M., Britschgi, M., Vardarajan, B., Huang, R. P., Kirby, E. D., Abbey, R., Boeve, B. F., Boxer, A. L., Farrer, L. A., Finch, N., Graff-Radford, N. R., Head, E., Hofree, M., Huang, R., Johns, H., Karydas, A., Knopman, D. S., Loboda, A., Masliah, E. & 10 others, Narasimhan, R., Petersen, R. C., Podtelezhnikov, A., Pradhan, S., Rademakers, R., Sun, C. H., Younkin, S. G., Miller, B. L., Ideker, T. & Wyss-Coray, T., Apr 26 2016, In : Molecular neurodegeneration. 11, 1, 31.

Research output: Contribution to journalArticle

15 Scopus citations
27 Scopus citations

Neuropathologic differences by race from the National Alzheimer's Coordinating Center

Graff-Radford, N. R., Besser, L. M., Crook, J. E., Kukull, W. A. & Dickson, D. W., Jun 1 2016, In : Alzheimer's and Dementia. 12, 6, p. 669-677 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Prosaposin is a regulator of progranulin levels and oligomerization

Nicholson, A. M., Finch, N. C. A., Almeida, M., Perkerson, R. B., Van Blitterswijk, M., Wojtas, A., Cenik, B., Rotondo, S., Inskeep, V., Almasy, L., Dyer, T., Peralta, J., Jun, G., Wood, A. R., Frayling, T. M., Fuchsberger, C., Fowler, S., Teslovich, T. M., Manning, A. K., Kumar, S. & 20 others, Curran, J., Lehman, D., Abecasis, G., Duggirala, R., Pottier, C., Zahir, H. A., Crook, J. E., Karydas, A., Mitic, L., Sun, Y., Dickson, D. W., Bu, G., Herz, J., Yu, G., Miller, B. L., Ferguson, S., Petersen, R. C., Graff-Radford, N., Blangero, J. & Rademakers, R., Jun 30 2016, In : Nature communications. 7, 11992.

Research output: Contribution to journalArticle

24 Scopus citations

RAB39B gene mutations are not a common cause of Parkinson's disease or dementia with Lewy bodies

Hodges, K., Brewer, S. S., Labbé, C., Soto-Ortolaza, A. I., Walton, R. L., Strongosky, A. J., Uitti, R. J., Van Gerpen, J. A., Taner, N., Kantarci, K. M., Lowe, V., Parisi, J. E., Savica, R., Graff-Radford, J., Jones, D. T., Knopman, D. S., Petersen, R. C., Murray, M. E., Graff Radford, N. R., Ferman, T. J. & 5 others, Dickson, D. W., Wszolek, Z. K., Boeve, B. F., Ross, O. A. & Lorenzo-Betancor, O., Sep 1 2016, In : Neurobiology of Aging. 45, p. 107-108 2 p.

Research output: Contribution to journalArticle

11 Scopus citations

Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts

Kramer, N. J., Carlomagno, Y., Zhang, Y., Almeida, S., Cook, C., Gendron, T. D., Prudencio, M., Van Blitterswijk, M., Belzil, V., Couthouis, J., Paul, J. W., Goodman, L. D., Daughrity, L., Chew, J., Garrett, A., Pregent, L., Jansen-West, K., Tabassian, L. J., Rademakers, R. V., Boylan, K. & 16 others, Graff Radford, N. R., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Boeve, B. F., Deng, N., Feng, Y., Cheng, T. H., Dickson, D. W., Cohen, S. N., Bonini, N. M., Link, C. D., Gao, F. B., Petrucelli, L. & Gitler, A. D., Aug 12 2016, In : Science. 353, 6300, p. 708-712 5 p.

Research output: Contribution to journalArticle

52 Scopus citations

Study of LRRK2 variation in tauopathy: Progressive supranuclear palsy and corticobasal degeneration

Sanchez-Contreras, M., Heckman, M. G., Tacik, P., Diehl, N., Brown, P. H., Soto-Ortolaza, A. I., Christopher, E. A., Walton, R. L., Ross, O. A., Golbe, L. I., Graff Radford, N. R., Wszolek, Z. K., Dickson, D. W. & Rademakers, R. V., 2016, (Accepted/In press) In : Movement Disorders.

Research output: Contribution to journalArticle

12 Scopus citations

The presenilin 1 p.Gly206Ala mutation is a frequent cause of early-onset alzheimer’s disease in Hispanics in Florida

Ravenscroft, T. A., Pottier, C., Murray, M. E., Baker, M., Christopher, E., Levitch, D., Brown, P. H., Barker, W., Duara, R., Greig-Custo, M., Betancourt, A., English, M., Sun, X., Taner, N., Graff Radford, N. R., Dickson, D. W. & Rademakers, R. V., 2016, In : American Journal of Neurodegenerative Diseases. 5, 1, p. 94-101 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

The role of cardiovascular risk factors and stroke in familial Alzheimer disease

Tosto, G., Bird, T. D., Bennett, D. A., Boeve, B. F., Brickman, A. M., Cruchaga, C., Faber, K., Foroud, T. M., Farlow, M., Goate, A. M., Graff Radford, N. R., Lantigua, R., Manly, J., Ottman, R., Rosenberg, R., Schaid, D. J., Schupf, N., Stern, Y., Sweet, R. A. & Mayeux, R., Oct 1 2016, In : JAMA Neurology. 73, 10, p. 1231-1237 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

TYROBP genetic variants in early-onset Alzheimer's disease

Pottier, C., Ravenscroft, T. A., Brown, P. H., Finch, N. C. A., Baker, M., Parsons, M., Asmann, Y. W., Ren, Y., Christopher, E., Levitch, D., van Blitterswijk, M., Cruchaga, C., Campion, D., Nicolas, G., Richard, A. C., Guerreiro, R., Bras, J. T., Zuchner, S., Gonzalez, M. A., Bu, G. & 10 others, Younkin, S., Knopman, D. S., Josephs, K. A., Parisi, J. E., Petersen, R. C., Ertekin-Taner, N., Graff-Radford, N. R., Boeve, B. F., Dickson, D. W. & Rademakers, R., Dec 1 2016, In : Neurobiology of aging. 48, p. 222.e9-222.e15

Research output: Contribution to journalArticle

29 Scopus citations
2015

Association of long runs of homozygosity with Alzheimer disease among African American individuals

Ghani, M., Reitz, C., Cheng, R., Vardarajan, B. N., Jun, G., Sato, C., Naj, A., Rajbhandary, R., Wang, L. S., Valladares, O., Lin, C. F., Larson, E. B., Graff-Radford, N. R., Evans, D., De Jager, P. L., Crane, P. K., Buxbaum, J. D., Murrell, J. R., Raj, T., Ertekin-Taner, N. & 153 others, Logue, M., Baldwin, C. T., Green, R. C., Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P. A., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hendrie, H., Hall, K. S., Goate, A. M., Byrd, G. S., Kukull, W. A., Foroud, T. M., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Lee, J. H., Schellenberg, G. D., St. George-Hyslop, P., Mayeux, R., Rogaeva, E., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Barber, R., Barmada, M. M., Beach, T. G., Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cai, G., Cairns, N. J., Cao, C., Carlson, C. S., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Cruchaga, C., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Faber, K. M., Fallon, K. B., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Haroutunian, V., Harrell, L. E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., LaFerla, F. M., Lah, J. J., Lang-Walker, R., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Olichney, J. M., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Ringman, J. M., Roberson, E. D., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L., Nov 2015, In : JAMA neurology. 72, 11, p. 1313-1323 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study

Alzheimer’s Disease Genetics Consortium, The GERAD1 Consortium & EPIC-InterAct Consortium, Jun 1 2015, In : PLoS Medicine. 12, 6, e1001841.

Research output: Contribution to journalArticle

69 Scopus citations

A truncating SOD1 mutation, p.Gly141X, is associated with clinical and pathologic heterogeneity, including frontotemporal lobar degeneration

Nakamura, M., Bieniek, K. F., Lin, W. L., Graff-Radford, N. R., Murray, M. E., Castanedes-Casey, M., Desaro, P., Baker, M. C., Rutherford, N. J., Robertson, J., Rademakers, R., Dickson, D. W. & Boylan, K. B., Jul 17 2015, In : Acta neuropathologica. 130, 1, p. 145-157 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Cerebellar c9RAN proteins associate with clinical and neuropathological characteristics of C9ORF72 repeat expansion carriers

Gendron, T. F., van Blitterswijk, M., Bieniek, K. F., Daughrity, L. M., Jiang, J., Rush, B. K., Pedraza, O., Lucas, J. A., Murray, M. E., Desaro, P., Robertson, A., Overstreet, K., Thomas, C. S., Crook, J. E., Castanedes-Casey, M., Rousseau, L., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C. & 9 others, Boeve, B. F., Graff-Radford, N. R., Rademakers, R., Lagier-Tourenne, C., Edbauer, D., Cleveland, D. W., Dickson, D. W., Petrucelli, L. & Boylan, K. B., Oct 26 2015, In : Acta neuropathologica. 130, 4, p. 559-573 15 p.

Research output: Contribution to journalArticle

50 Scopus citations

Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease

Wang, F., Gordon, B. A., Ryman, D. C., Ma, S., Xiong, C., Hassenstab, J., Goate, A., Fagan, A. M., Cairns, N. J., Marcus, D. S., McDade, E., Ringman, J. M., Graff Radford, N. R., Ghetti, B., Farlow, M. R., Sperling, R., Salloway, S., Schofield, P. R., Masters, C. L., Martins, R. N. & 8 others, Rossor, M. N., Jucker, M., Danek, A., Förster, S., Lane, C. A. S., Morris, J. C., Benzinger, T. L. S. & Bateman, R. J., Sep 1 2015, In : Neurology. 85, 9, p. 790-798 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Chronic traumatic encephalopathy pathology in a neurodegenerative disorders brain bank

Bieniek, K. F., Ross, O. A., Cormier, K. A., Walton, R. L., Soto-Ortolaza, A., Johnston, A. E., DeSaro, P., Boylan, K. B., Graff-Radford, N. R., Wszolek, Z. K., Rademakers, R., Boeve, B. F., McKee, A. C. & Dickson, D. W., Dec 1 2015, In : Acta neuropathologica. 130, 6, p. 877-889 13 p.

Research output: Contribution to journalArticle

113 Scopus citations

Clinicopathologic and <sup>11</sup>C-Pittsburgh compound B implications of Thal amyloid phase across the Alzheimer's disease spectrum

Murray, M. E., Lowe, V., Graff Radford, N. R., Liesinger, A. M., Cannon, A., Przybelski, S. A., Rawal, B., Parisi, J. E., Petersen, R. C., Kantarci, K. M., Ross, O. A., Duara, R., Knopman, D. S., Jack, C. R. J. & Dickson, D. W., May 1 2015, In : Brain. 138, 5, p. 1370-1381 12 p.

Research output: Contribution to journalArticle

167 Scopus citations

DNAJC13 p.Asn855Ser mutation screening in Parkinson's disease and pathologically confirmed Lewy body disease patients

Lorenzo-Betancor, O., Ogaki, K., Soto-Ortolaza, A. I., Labbe, C., Walton, R. L., Strongosky, A. J., Van Gerpen, J. A., Uitti, R. J., McLean, P. J., Springer, W., Siuda, J., Opala, G., Krygowska-Wajs, A., Barcikowska, M., Czyzewski, K., Mccarthy, A., Lynch, T., Puschmann, A., Rektorova, I., Sanotsky, Y. & 10 others, Vilariño-Güell, C., Farrer, M. J., Ferman, T. J., Boeve, B. F., Petersen, R. C., Parisi, J. E., Graff Radford, N. R., Dickson, D. W., Wszolek, Z. K. & Ross, O. A., Sep 1 2015, In : European Journal of Neurology. 22, 9, p. 1323-1325 3 p.

Research output: Contribution to journalArticle

13 Scopus citations

Factors associated with the onset and persistence of post-lumbar puncture headache

Monserrate, A. E., Ryman, D. C., Ma, S., Xiong, C., Noble, J. M., Ringman, J. M., Morris, J. C., Danek, A., Müller-Sarnowski, F., Clifford, D. B., McDade, E. M., Brooks, W. S., Darby, D. G., Masters, C. L., Weston, P. S. J., Farlow, M. R., Graff Radford, N. R., Salloway, S. P., Fagan, A. M., Oliver, A. & 2 others, Bateman, R. J. & Dominantly Inherited Alzheimer Network, I. A. N., Mar 1 2015, In : JAMA Neurology. 72, 3, p. 325-332 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE

Alzheimer's Disease Neuroimaging Initiative, May 19 2015, In : Nature communications. 6, 6760.

Research output: Contribution to journalArticle

108 Scopus citations

Genetically-controlled Vesicle-Associated Membrane Protein 1 expression may contribute to Alzheimer's pathophysiology and susceptibility

Sevlever, D., Zou, F., Ma, L., Carrasquillo, S., Crump, M. G., Culley, O. J., Hunter, T. A., Bisceglio, G. D., Younkin, L., Allen, M., Carrasquillo, M. M., Sando, S. B., Aasly, J. O., Dickson, D. W., Graff-Radford, N. R., Petersen, R. C., Morgan, K. & Belbin, O., Apr 9 2015, In : Molecular neurodegeneration. 10, 1, 18.

Research output: Contribution to journalArticle

6 Scopus citations

Genetic variants associated with susceptibility to psychosis inlate-onset Alzheimer's disease families

NIA-LOAD/NCRAD Family Study Group, Apr 20 2015, (Accepted/In press) In : Neurobiology of Aging.

Research output: Contribution to journalArticle

6 Scopus citations

Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy

Kouri, N., Ross, O. A., Dombroski, B., Younkin, C. S., Serie, D. J., Soto-Ortolaza, A., Baker, M., Finch, N. C. A., Yoon, H., Kim, J., Fujioka, S., Mclean, C. A., Ghetti, B., Spina, S., Cantwell, L. B., Farlow, M. R., Grafman, J., Huey, E. D., Ryung Han, M., Beecher, S. & 34 others, Geller, E. T., Kretzschmar, H. A., Roeber, S., Gearing, M., Juncos, J. L., Vonsattel, J. P. G., Van Deerlin, V. M., Grossman, M., Hurtig, H. I., Gross, R. G., Arnold, S. E., Trojanowski, J. Q., Lee, V. M., Wenning, G. K., White, C. L., Höglinger, G. U., Müller, U., Devlin, B., Golbe, L. I., Crook, J., Parisi, J. E., Boeve, B. F., Josephs, K. A., Wszolek, Z. K., Uitti, R. J., Graff-Radford, N. R., Litvan, I., Younkin, S. G., Wang, L. S., Ertekin-Taner, N., Rademakers, R., Hakonarsen, H., Schellenberg, G. D. & Dickson, D. W., Jun 16 2015, In : Nature communications. 6, 7247.

Research output: Contribution to journalArticle

83 Scopus citations

Jump from Pre-mutation to Pathologic Expansion in C9orf72

Xi, Z., Van Blitterswijk, M., Zhang, M., McGoldrick, P., McLean, J. R., Yunusova, Y., Knock, E., Moreno, D., Sato, C., McKeever, P. M., Schneider, R., Keith, J., Petrescu, N., Fraser, P., Tartaglia, M. C., Baker, M. C., Graff Radford, N. R., Boylan, K. B., Dickson, D. W., Mackenzie, I. R. & 4 others, Rademakers, R. V., Robertson, J., Zinman, L. & Rogaeva, E., Mar 12 2015, (Accepted/In press) In : American Journal of Human Genetics.

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32 Scopus citations

Late-onset Alzheimer disease risk variants mark brain regulatory loci

Allen, M., Kachadoorian, M., Carrasquillo, M. M., Karhade, A., Manly, L., Burgess, J. D., Wang, C., Serie, D., Wang, X., Siuda, J., Zou, F., Chai, H. S., Younkin, C., Crook, J., Medway, C., Nguyen, T., Ma, L., Malphrus, K., Lincoln, S., Petersen, R. C. & 5 others, Graff-Radford, N. R., Asmann, Y. W., Dickson, D. W., Younkin, S. G. & Ertekin-Taner, N., Aug 2015, In : Neurology: Genetics. 1, 2, e15.

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25 Scopus citations

Late-onset Alzheimer's risk variants in memory decline, incident mild cognitive impairment, and Alzheimer's disease

Carrasquillo, M. M., Crook, J. E., Pedraza, O., Thomas, C. S., Pankratz, V. S., Allen, M., Nguyen, T., Malphrus, K. G., Ma, L., Bisceglio, G. D., Roberts, R. O., Lucas, J. A., Smith, G. E., Ivnik, R. J., Machulda, M. M., Graff-Radford, N. R., Petersen, R. C., Younkin, S. G. & Ertekin-Taner, N., Jan 1 2015, In : Neurobiology of aging. 36, 1, p. 60-67 8 p.

Research output: Contribution to journalArticle

55 Scopus citations

Mitochondrial targeting sequence variants of the CHCHD2 gene are a risk for Lewy body disorders

Ogaki, K., Koga, S., Heckman, M. G., Fiesel, F., Ando, M., Labbé, C., Lorenzo-Betancor, O., Moussaud-Lamodière, E. L., Soto-Ortolaza, A. I., Walton, R. L., Strongosky, A. J., Uitti, R. J., McCarthy, A., Lynch, T., Siuda, J., Opala, G., Rudzinska, M., Krygowska-Wajs, A., Barcikowska, M., Czyzewski, K. & 12 others, Puschmann, A., Nishioka, K., Funayama, M., Hattori, N., Parisi, J. E., Petersen, R. C., Graff Radford, N. R., Boeve, B. F., Springer, W., Wszolek, Z. K., Dickson, D. W. & Ross, O. A., Dec 8 2015, In : Neurology. 85, 23, p. 2016-2025 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Novel clinical associations with specific C9ORF72 transcripts in patients with repeat expansions in C9ORF72

van Blitterswijk, M., Gendron, T. F., Baker, M. C., DeJesus-Hernandez, M., Finch, N. C. A., Brown, P. H., Daughrity, L. M., Murray, M. E., Heckman, M. G., Jiang, J., Lagier-Tourenne, C., Edbauer, D., Cleveland, D. W., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Petrucelli, L., Boeve, B. F., Graff-Radford, N. R. & 3 others, Boylan, K. B., Dickson, D. W. & Rademakers, R., Dec 1 2015, In : Acta neuropathologica. 130, 6, p. 863-876 14 p.

Research output: Contribution to journalArticle

46 Scopus citations

Rarity of the alzheimer disease-protective APP A673T variant in the United States

National Institute on Aging-Late-Onset Alzheimer's Disease (NIA-LOAD) Family Study & Alzheimer's Disease Genetics Consortium, Feb 1 2015, In : JAMA neurology. 72, 2, p. 209-216 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Role for the microtubule-associated protein tau variant p.A152T in risk of α-synucleinopathies

Labbé, C., Ogaki, K., Lorenzo-Betancor, O., Soto-Ortolaza, A. I., Walton, R. L., Rayaprolu, S., Fujioka, S., Murray, M. E., Heckman, M. G., Puschmann, A., McCarthy, A., Lynch, T., Siuda, J., Opala, G., Rudzinska, M., Krygowska-Wajs, A., Barcikowska, M., Czyzewski, K., Sanotsky, Y., Rektorová, I. & 16 others, McLean, P. J., Rademakers, R. V., Taner, N., Hassan, A., Ahlskog, J. E., Boeve, B. F., Petersen, R. C., Maraganore, D. M., Adler, C. H., Ferman, T. J., Parisi, J. E., Graff Radford, N. R., Uitti, R. J., Wszolek, Z. K., Dickson, D. W. & Ross, O. A., Nov 10 2015, In : Neurology. 85, 19, p. 1680-1686 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

TREM2 is associated with increased risk for Alzheimer's disease in African Americans

Jin, S. C., Carrasquillo, M. M., Benitez, B. A., Skorupa, T., Carrell, D., Patel, D., Lincoln, S., Krishnan, S., Kachadoorian, M., Reitz, C., Mayeux, R., Wingo, T. S., Lah, J. J., Levey, A. I., Murrell, J., Hendrie, H., Foroud, T., Graff-Radford, N. R., Goate, A. M., Cruchaga, C. & 1 others, Ertekin-Taner, N., Apr 10 2015, In : Molecular Neurodegeneration. 10, 1, 19.

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70 Scopus citations

Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease

Pottier, C., Bieniek, K. F., Finch, N. C., van de Vorst, M., Baker, M., Perkersen, R., Brown, P., Ravenscroft, T., van Blitterswijk, M., Nicholson, A. M., DeTure, M., Knopman, D. S., Josephs, K. A., Parisi, J. E., Petersen, R. C., Boylan, K. B., Boeve, B. F., Graff-Radford, N. R., Veltman, J. A., Gilissen, C. & 3 others, Murray, M. E., Dickson, D. W. & Rademakers, R., Jul 17 2015, In : Acta neuropathologica. 130, 1, p. 77-92 16 p.

Research output: Contribution to journalArticle

150 Scopus citations
2014

Abnormal daytime sleepiness in dementia with Lewy bodies compared to Alzheimer's disease using the Multiple Sleep Latency Test

Ferman, T. J., Smith, G. E., Dickson, D. W., Graff-Radford, N. R., Lin, S. C., Wszolek, Z., Van Gerpen, J. A., Uitti, R., Knopman, D. S., Petersen, R. C., Parisi, J. E., Silber, M. H. & Boeve, B. F., Jan 1 2014, In : Alzheimer's Research and Therapy. 6, 6, 76.

Research output: Contribution to journalArticle

29 Scopus citations

Age-specific incidence rates for dementia and alzheimer disease in NIA-LOAD/NCRAD and EFIGA families: National Institute on Aging Genetics Initiative for late-onset Alzheimer disease/National Cell Repository for Alzheimer disease (NIA-LOAD/NCRAD) and Estudio Familiar de Influencia Genetica en Alzheimer (EFIGA)

Vardarajan, B. N., Faber, K. M., Bird, T. D., Bennett, D. A., Rosenberg, R., Boeve, B. F., Graff-Radford, N. R., Goate, A. M., Farlow, M., Sweet, R. A., Lantigua, R., Medrano, M. Z., Ottman, R., Schaid, D. J., Foroud, T. M. & Mayeux, R., Mar 2014, In : JAMA neurology. 71, 3, p. 315-323 9 p.

Research output: Contribution to journalArticle

26 Scopus citations