Neill R Graff Radford, MD

  • 32870 Citations
  • 95 Scopus h-Index
1981 …2020

Research output per year

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Research Output

2008

Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia

Rademakers, R., Eriksen, J. L., Baker, M., Robinson, T., Ahmed, Z., Lincoln, S. J., Finch, N., Rutherford, N. J., Crook, R. J., Josephs, K. A., Boeve, B. F., Knopman, D. S., Petersen, R. C., Parisi, J. E., Caselli, R. J., Wszolek, Z. K., Uitti, R. J., Feldman, H., Hutton, M. L., Mackenzie, I. R. & 2 others, Graff-Radford, N. R. & Dickson, D. W., Nov 19 2008, In : Human molecular genetics. 17, 23, p. 3631-3642 12 p.

Research output: Contribution to journalArticle

208 Scopus citations

Detecting dementia with the mini-mental state examination in highly educated individuals

O'Bryant, S. E., Humphreys, J. D., Smith, G. E., Ivnik, R. J., Graff-Radford, N. R., Petersen, R. C. & Lucas, J. A., Jul 1 2008, In : Archives of neurology. 65, 7, p. 963-967 5 p.

Research output: Contribution to journalArticle

340 Scopus citations

Development of methodology for conducting clinical trials in frontotemporal lobar degeneration

Knopman, D. S., Kramer, J. H., Boeve, B. F., Caselli, R. J., Graff-Radford, N. R., Mendez, M. F., Miller, B. L. & Mercaldo, N., Nov 1 2008, In : Brain. 131, 11, p. 2957-2968 12 p.

Research output: Contribution to journalArticle

181 Scopus citations

Early onset familial alzheimer disease with spastic paraparesis, dysarthria, and seizures and N135S mutation in PSEN1

Rudzinski, L. A., Fletcher, R. M., Dickson, D. W., Crook, R., Hutton, M. L., Adamson, J. & Graff-Radford, N. R., Jul 1 2008, In : Alzheimer disease and associated disorders. 22, 3, p. 299-307 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Frontotemporal lobar degeneration with ubiquitin-positive, but TDP-43-negative inclusions

Josephs, K. A., Lin, W. L., Ahmed, Z., Stroh, D. A., Graff-Radford, N. R. & Dickson, D. W., Aug 1 2008, In : Acta neuropathologica. 116, 2, p. 159-167 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

Longitudinal MRI findings from the vitamin E and donepezil treatment study for MCI

the Alzheimer’s Disease Cooperative Study (ADCS), Sep 1 2008, In : Neurobiology of aging. 29, 9, p. 1285-1295 11 p.

Research output: Contribution to journalArticle

109 Scopus citations

Novel mutations in TARDBP(TDP-43) in patients with familial amyotrophic lateral sclerosis

Rutherford, N. J., Zhang, Y. J., Baker, M., Gass, J. M., Finch, N. C. A., Xu, Y. F., Stewart, H., Kelley, B. J., Kuntz, K., Crook, R. J. P., Sreedharan, J., Vance, C., Sorenson, E., Lippa, C., Bigio, E. H., Geschwind, D. H., Knopman, D. S., Mitsumoto, H., Petersen, R. C., Cashman, N. R. & 11 others, Hutton, M., Shaw, C. E., Boylan, K. B., Boeve, B., Graff-Radford, N. R., Wszolek, Z. K., Caselli, R. J., Dickson, D. W., Mackenzie, I. R., Petrucelli, L. & Rademakers, R., Sep 1 2008, In : PLoS genetics. 4, 9, e1000193.

Research output: Contribution to journalArticle

301 Scopus citations

Plasma amyloid β protein is elevated in late-onset Alzheimer disease families

Ertekin-Taner, N., Younkin, L. H., Yager, D. M., Parfitt, F., Baker, M. C., Asthana, S., Hutton, M. L., Younkin, S. G. & Graff-Radford, N. R., Feb 2008, In : Neurology. 70, 8, p. 596-606 11 p.

Research output: Contribution to journalArticle

65 Scopus citations

Progressive aphasia secondary to Alzheimer disease vs FTLD pathology

Josephs, K. A., Whitwell, J. L., Duffy, J. R., Vanvoorst, W. A., Strand, E. A., Hu, W. T., Boeve, B. F., Graff-Radford, N. R., Parisi, J. E., Knopman, D. S., Dickson, D. W., Jack, C. R. & Petersen, R. C., Jan 2008, In : Neurology. 70, 1, p. 25-34 10 p.

Research output: Contribution to journalArticle

119 Scopus citations

Sex-dependent association of a common low-density lipoprotein receptor polymorphism with RNA splicing efficiency in the brain and Alzheimer's disease

Zou, F., Gopalraj, R. K., Lok, J., Zhu, H., Ling, I. F., Simpson, J. F., Tucker, H. M., Kelly, J. F., Younkin, S. G., Dickson, D. W., Petersen, R. C., Graff-Radford, N. R., Bennett, D. A., Crook, J. E., Younkin, S. G. & Estus, S., Apr 1 2008, In : Human molecular genetics. 17, 7, p. 929-935 7 p.

Research output: Contribution to journalArticle

44 Scopus citations
113 Scopus citations
2007

A plateau in pre-Alzheimer memory decline: Evidence for compensatory mechanisms?

Smith, G. E., Pankratz, V. S., Negash, S., Machulda, M. M., Petersen, R. C., Boeve, B. F., Knopman, D. S., Lucas, J. A., Ferman, T. J., Graff-Radford, N. & Ivnik, R. J., Jul 1 2007, In : Neurology. 69, 2, p. 133-139 7 p.

Research output: Contribution to journalArticle

50 Scopus citations
318 Scopus citations
20 Scopus citations

Frontotemporal dementia

Graff-Radford, N. R. & Woodruff, B. K., Feb 1 2007, In : Seminars in Neurology. 27, 1, p. 48-57 10 p.

Research output: Contribution to journalReview article

93 Scopus citations

Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500,288 single-nucleotide polymorphisms

Melquist, S., Craig, D. W., Huentelman, M. J., Crook, R., Pearson, J. V., Baker, M., Zismann, V. L., Gass, J., Adamson, J., Szelinger, S., Corneveaux, J., Cannon, A., Coon, K. D., Lincoln, S., Adler, C., Tuite, P., Calne, D. B., Bigio, E. H., Uitti, R. J., Wszolek, Z. K. & 8 others, Golbe, L. I., Caselli, R. J., Graff-Radford, N., Litvan, I., Farrer, M. J., Dickson, D. W., Hutton, M. & Stephan, D. A., Apr 2007, In : American journal of human genetics. 80, 4, p. 769-778 10 p.

Research output: Contribution to journalArticle

53 Scopus citations

Longitudinal tracking of FTLD: Toward developing clinical trial methodology

Knopman, D. S., Boeve, B. S., Caselli, R. J., Graff-Radford, N. R., Kramer, J. H., Mendez, M. F. & Miller, B. L., Oct 1 2007, In : Alzheimer disease and associated disorders. 21, 4, p. S58-S63

Research output: Contribution to journalArticle

14 Scopus citations

Neuropathologic features of frontotemporal lobar degeneration with ubiquitin-positive inclusions with progranulin gene (PGRN) mutations

Josephs, K. A., Ahmed, Z., Katsuse, O., Parisi, J. F., Boeve, B. F., Knopman, D. S., Petersen, R. C., Davies, P., Duara, R., Graff-Radford, N. R., Uitti, R. J., Rademakers, R., Adamson, J., Baker, M., Hutton, M. L. & Dickson, D. W., Feb 1 2007, In : Journal of Neuropathology and Experimental Neurology. 66, 2, p. 142-151 10 p.

Research output: Contribution to journalArticle

147 Scopus citations
34 Scopus citations

Normal pressure hydrocephalus

Graff-Radford, N. R., Apr 1 2007, In : CONTINUUM Lifelong Learning in Neurology. 13, 2, p. 144-164 21 p.

Research output: Contribution to journalReview article

2 Scopus citations

Normal Pressure Hydrocephalus

Graff-Radford, N. R., Aug 1 2007, In : Neurologic clinics. 25, 3, p. 809-832 24 p.

Research output: Contribution to journalReview article

35 Scopus citations

Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C→T (Arg493X) mutation: an international initiative

Rademakers, R., Baker, M., Gass, J., Adamson, J., Huey, E. D., Momeni, P., Spina, S., Coppola, G., Karydas, A. M., Stewart, H., Johnson, N., Hsiung, G. Y., Kelley, B., Kuntz, K., Steinbart, E., Wood, E. M. C., Yu, C. E., Josephs, K., Sorenson, E., Womack, K. B. & 30 others, Weintraub, S., Pickering-Brown, S. M., Schofield, P. R., Brooks, W. S., Van Deerlin, V. M., Snowden, J., Clark, C. M., Kertesz, A., Boylan, K., Ghetti, B., Neary, D., Schellenberg, G. D., Beach, T. G., Mesulam, M., Mann, D., Grafman, J., Mackenzie, I. R., Feldman, H., Bird, T., Petersen, R., Knopman, D., Boeve, B., Geschwind, D. H., Miller, B., Wszolek, Z., Lippa, C., Bigio, E. H., Dickson, D., Graff-Radford, N. & Hutton, M., Oct 2007, In : Lancet Neurology. 6, 10, p. 857-868 12 p.

Research output: Contribution to journalArticle

169 Scopus citations

Preface

Graff-Radford, N. R., Aug 1 2007, In : Neurologic clinics. 25, 3, p. xi-xii

Research output: Contribution to journalEditorial

Progranulin mutations and amyotrophic lateral sclerosis or amyotrophic lateral sclerosis-frontotemporal dementia phenotypes

Schymick, J. C., Yang, Y., Andersen, P. M., Vonsattel, J. P., Greenway, M., Momeni, P., Elder, J., Chiò, A., Restagno, G., Robberecht, W., Dahlberg, C., Mukherjee, O., Goate, A., Graff-Radford, N., Caselli, R. J., Hutton, M., Gass, J., Cannon, A., Rademakers, R., Singleton, A. B. & 4 others, Hardiman, O., Rothstein, J., Hardy, J. & Traynor, B. J., Jul 1 2007, In : Journal of Neurology, Neurosurgery and Psychiatry. 78, 7, p. 754-756 3 p.

Research output: Contribution to journalArticle

101 Scopus citations

Progranulin mutations in primary progressive aphasia: The PPA1 and PPA3 families

Mesulam, M., Johnson, N., Krefft, T. A., Gass, J. M., Cannon, A. D., Adamson, J. L., Bigio, E. H., Weintraub, S., Dickson, D. W., Hutton, M. L. & Graff-Radford, N. R., Jan 1 2007, In : Archives of neurology. 64, 1, p. 43-47 5 p.

Research output: Contribution to journalArticle

121 Scopus citations

Reliable change on the Dementia Rating Scale

Pedraza, O., Smith, G. E., Ivnik, R. J., Willis, F. B., Ferman, T. J., Petersen, R. C., Graff-Radford, N. R. & Lucas, J. A., Jul 2007, In : Journal of the International Neuropsychological Society. 13, 4, p. 716-720 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Safety, tolerability, pharmacokinetics, and Aβ levels after short-term administration of R-flurbiprofen in healthy elderly individuals

Galasko, D. R., Graff-Radford, N., May, S., Hendrix, S., Cottrell, B. A., Sagi, S. A., Mather, G., Laughlin, M., Zavitz, K. H., Swabb, E., Golde, T. E., Murphy, M. P. & Koo, E. H., Oct 1 2007, In : Alzheimer disease and associated disorders. 21, 4, p. 292-299 8 p.

Research output: Contribution to journalArticle

106 Scopus citations

TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease

Amador-Ortiz, C., Lin, W. L., Ahmed, Z., Personett, D., Davies, P., Duara, R., Graff-Radford, N. R., Hutton, M. L. & Dickson, D. W., May 1 2007, In : Annals of neurology. 61, 5, p. 435-445 11 p.

Research output: Contribution to journalArticle

514 Scopus citations

The ability to pun may be retained in Alzheimer disease

Hawkins, D. B. & Graff-Radford, N., Feb 1 2007, In : Neurocase. 13, 1, p. 50-54 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

Rogaeva, E., Meng, Y., Lee, J. H., Gu, Y., Kawarai, T., Zou, F., Katayama, T., Baldwin, C. T., Cheng, R., Hasegawa, H., Chen, F., Shibata, N., Lunetta, K. L., Pardossi-Piquard, R., Bohm, C., Wakutani, Y., Cupples, L. A., Cuenco, K. T., Green, R. C., Pinessi, L. & 21 others, Rainero, I., Sorbi, S., Bruni, A., Duara, R., Friedland, R. P., Inzelberg, R., Hampe, W., Bujo, H., Song, Y. Q., Andersen, O. M., Willnow, T. E., Graff-Radford, N., Petersen, R. C., Dickson, D., Der, S. D., Fraser, P. E., Schmitt-Ulms, G., Younkin, S., Mayeux, R., Farrer, L. A. & St. George-Hyslop, P., Feb 1 2007, In : Nature Genetics. 39, 2, p. 168-177 10 p.

Research output: Contribution to journalArticle

760 Scopus citations
2006

A cost effective method of identifying and recruiting persons over 80 free of dementia or mild cognitive impairment

Graff-Radford, N. R., Ferman, T. J., Lucas, J. A., Johnson, H. K., Parfitt, F. C., Heckman, M. G., Todd, M., Sadowsky, C., Epstein, D. E. & Crook, J. E., Apr 1 2006, In : Alzheimer disease and associated disorders. 20, 2, p. 101-104 4 p.

Research output: Contribution to journalArticle

21 Scopus citations

Family history of dementia is a risk factor for Lewy body disease

Woodruff, B. K., Graff-Radford, N. R., Ferman, T. J., Dickson, D. W., Delucia, M. W., Crook, J. E., Arvanitakis, Z., Brassler, S., Waters, C., Barker, W. & Duara, R., Jun 1 2006, In : Neurology. 66, 12, p. 1949-1950 2 p.

Research output: Contribution to journalArticle

17 Scopus citations

Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration

Gass, J., Cannon, A., Mackenzie, I. R., Boeve, B., Baker, M., Adamson, J., Crook, R., Melquist, S., Kuntz, K., Petersen, R., Josephs, K., Pickering-Brown, S. M., Graff-Radford, N., Uitti, R., Dickson, D., Wszolek, Z., Gonzalez, J., Beach, T. G., Bigio, E., Johnson, N. & 10 others, Weintraub, S., Mesulam, M., White, C. L., Woodruff, B., Caselli, R., Hsiung, G. Y., Feldman, H., Knopman, D., Hutton, M. & Rademakers, R., Oct 15 2006, In : Human molecular genetics. 15, 20, p. 2988-3001 14 p.

Research output: Contribution to journalArticle

428 Scopus citations
118 Scopus citations

The Uniform Data Set (UDS): Clinical and cognitive variables and descriptive data from Alzheimer disease centers

Morris, J. C., Weintraub, S., Chui, H. C., Cummings, J., DeCarli, C., Ferris, S., Foster, N. L., Galasko, D., Graff-Radford, N., Peskind, E. R., Beekly, D., Ramos, E. M. & Kukull, W. A., Oct 1 2006, In : Alzheimer disease and associated disorders. 20, 4, p. 210-216 7 p.

Research output: Contribution to journalArticle

429 Scopus citations
2005

A brief report on WAIS-R normative data collection in Mayo's Older African Americans Normative Studies

Lucas, J. A., Ivnik, R. J., Smith, G. E., Ferman, T. J., Willis, F. B., Petersen, R. C. & Graff-Radford, N. R., Jun 1 2005, In : Clinical Neuropsychologist. 19, 2, p. 184-188 5 p.

Research output: Contribution to journalShort survey

18 Scopus citations

Different patterns of magnetic resonance imaging atrophy for frontotemporal lobar degeneration syndromes

Short, R. A., Broderick, D. F., Patton, A., Arvanitakis, Z. & Graff-Radford, N. R., Jul 1 2005, In : Archives of neurology. 62, 7, p. 1106-1110 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Elevated amyloid β protein (Aβ42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene

Ertekin-Taner, N., Roland, J., Feuk, L., Prince, J., Tucker, M., Younkin, L., Hella, M., Jain, S., Hackett, A., Scanlin, L., Kelly, J., Kihiko-Ehman, M., Neltner, M., Hersch, L., Kindy, M., Markesbery, W., Hutton, M., de Andrade, M., Petersen, R. C., Graff-Radford, N. & 3 others, Estus, S., Brookes, A. J. & Younkin, S. G., Feb 1 2005, In : Human molecular genetics. 14, 3, p. 447-460 14 p.

Research output: Contribution to journalArticle

48 Scopus citations

Mayo's older African American normative studies: Norms for the Mattis dementia rating scale

Rilling, L. M., Lucas, J. A., Ivnik, R. J., Smith, G. E., Willis, F. B., Ferman, T. J., Petersen, R. C. & Graff-Radford, N. R., Jun 1 2005, In : Clinical Neuropsychologist. 19, 2, p. 229-242 14 p.

Research output: Contribution to journalArticle

28 Scopus citations
22 Scopus citations
21 Scopus citations

Mayo's Older African Americans Normative Studies: Normative data for commonly used clinical neuropsychological measures

Lucas, J. A., Ivnik, R. J., Willis, F. B., Ferman, T. J., Smith, G. E., Parfitt, F. C., Petersen, R. C. & Graff-Radford, N. R., Jun 1 2005, In : Clinical Neuropsychologist. 19, 2, p. 162-183 22 p.

Research output: Contribution to journalArticle

61 Scopus citations

Mayo's Older African Americans Normative Studies: WMS-R norms for African American elders

Lucas, J. A., Ivnik, R. J., Smith, G. E., Ferman, T. J., Willis, F. B., Petersen, R. C. & Graff-Radford, N. R., Jun 1 2005, In : Clinical Neuropsychologist. 19, 2, p. 189-213 25 p.

Research output: Contribution to journalArticle

19 Scopus citations

Rate of progression differs in frontotemporal dementia and Alzheimer disease

Rascovsky, K., Salmon, D. P., Lipton, A. M., Leverenz, J. B., Decarli, C., Jagust, W. J., Clark, C. M., Mendez, M. F., Tang-Wai, D. F., Graff-Radford, N. R. & Galasko, D., Aug 9 2005, In : Neurology. 65, 3, p. 397-403 7 p.

Research output: Contribution to journalArticle

131 Scopus citations
2004

Clinical, genetic, and neuropathologic characteristics of posterior cortical atrophy

Tang-Wai, D. F., Graff-Radford, N. R., Boeve, B. F., Dickson, D. W., Parisi, J. E., Crook, R., Caselli, R. J., Knopman, D. S. & Petersen, R. C., Oct 12 2004, In : Neurology. 63, 7, p. 1168-1174 7 p.

Research output: Contribution to journalArticle

398 Scopus citations

Genetic Variants in a Haplotype Block Spanning IDE are Significantly Associated with Plasma Aβ42 Levels and Risk for Alzheimer Disease

Ertekin-Taner, N., Allen, M., Fadale, D., Scanlin, L., Younkin, L., Petersen, R. C., Graff-Radford, N. & Younkin, S. G., Apr 22 2004, In : Human mutation. 23, 4, p. 334-342 9 p.

Research output: Contribution to journalArticle

87 Scopus citations

Normal Pressure Hydrocephalus and Large Head Size

Krefft, T. A., Graff-Radford, N. R., Lucas, J. A. & Mortimer, J. A., Jan 1 2004, In : Alzheimer disease and associated disorders. 18, 1, p. 35-37 3 p.

Research output: Contribution to journalArticle

17 Scopus citations

Specific features that reliably differentiate DLB from AD and normal aging

Ferman, T. J., Smith, G. E., Boeve, B. F., Ivnik, R. J., Petersen, R. C., Knopman, D., Graff-Radford, N., Parisi, J. & Dickson, D. W., Jan 27 2004, In : Neurology. 62, 2, p. 181-187 7 p.

Research output: Contribution to journalArticle

262 Scopus citations
2003

Apolipoprotein ∈4 allele frequency in young Africans of Ugandan descent versus African Americans

Willis, F., Graff-Radford, N., Pinto, M., Lawson, L. S., Adamson, J., Epstein, D., Parfitt, F., Hutton, M. & O'Brien, P. C., Jan 1 2003, In : Journal of the National Medical Association. 95, 1, p. 71-76 6 p.

Research output: Contribution to journalReview article

7 Scopus citations