• 4111 Citations
  • 35 Scopus h-Index
20002019

Research output per year

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Research Output

2012

Detailed structural-functional analysis of the Krüppel-like factor 16 (KLF16) transcription factor reveals novel mechanisms for silencing Sp/KLF sites involved in metabolism and endocrinology

Daftary, G. S., Lomberk, G. A., Buttar, N. S., Allen, T. W., Grzenda, A., Zhang, J., Zheng, Y., Mathison, A. J., Gada, R. P., Calvo, E., Iovanna, J. L., Billadeau, D. D., Prendergast, F. G. & Urrutia, R., Mar 2 2012, In : Journal of Biological Chemistry. 287, 10, p. 7010-7025 16 p.

Research output: Contribution to journalArticle

25 Scopus citations

Distribution of Body Fat and Its Influence on Esophageal Inflammation and Dysplasia in Patients With Barrett's Esophagus

Nelsen, E. M., Kirihara, Y., Takahashi, N., Shi, Q. D., Lewis, J. T., Namasivayam, V., Buttar, N. S., Dunagan, K. T. & Iyer, P. G., Jul 2012, In : Clinical Gastroenterology and Hepatology. 10, 7, p. 728-734 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Krüppel-like factor 11 differentially couples to histone acetyltransferase and histone methyltransferase chromatin remodeling pathways to transcriptionally regulate dopamine D2 receptor in neuronal cells

Seo, S., Lomberk, G., Mathison, A., Buttar, N. S., Podratz, J., Calvo, E., Iovanna, J., Brimijoin, W. S., Windebank, A. J. & Urrutia, R., Apr 13 2012, In : Journal of Biological Chemistry. 287, 16, p. 12723-12735 13 p.

Research output: Contribution to journalArticle

26 Scopus citations

Medical and endoscopic management of high-grade dysplasia in Barrett's esophagus

Wang, K. K. N., Tian, J. M., Gorospe, E., Penfield, J., Iyer, P. G., Goddard, T., Wongkeesong, M., Buttar, N. S., Lutzke, L. & Krishnadath, S., May 2012, In : Diseases of the Esophagus. 25, 4, p. 349-355 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Placement of a covered stent for palliation of a cavitated colon cancer by using a novel over-the-scope technique (with video)

Samadder, N. J., Bonin, E. A., Buttar, N. S., Baron, T. H., Gostout, C. J., Topazian, M. & Wong Kee Song, L. M., Dec 2012, In : Gastrointestinal Endoscopy. 76, 6, p. 1175-1177 3 p.

Research output: Contribution to journalArticle

Placement of a covered stent for palliation of a cavitated colon cancer by using a novel over-the-scope technique (with video).

Samadder, N. J., Bonin, E. A., Buttar, N. S., Baron, T. H., Gostout, C. J., Topazian, M. & Song, L. M. W. K., Dec 2012, In : Gastrointestinal Endoscopy. 76, 6, p. 1275-1277 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Sequence-specific recruitment of heterochromatin protein 1 via interaction with Krüppel-like factor 11, a human transcription factor involved in tumor suppression and metabolic diseases

Lomberk, G., Mathison, A. J., Grzenda, A., Seo, S., DeMars, C. J., Rizvi, S., Bonilla-Velez, J., Calvo, E., Fernandez-Zapico, M. E., Iovanna, J., Buttar, N. S. & Urrutia, R., Apr 13 2012, In : Journal of Biological Chemistry. 287, 16, p. 13026-13039 14 p.

Research output: Contribution to journalArticle

38 Scopus citations

The Crosstalk of mTOR/S6K1 and Hedgehog Pathways

Wang, Y., Ding, Q., Yen, C. J., Xia, W., Izzo, J. G., Lang, J. Y., Li, C. W., Hsu, J. L., Miller, S. A., Wang, X., Lee, D. F., Hsu, J. M., Huo, L., LaBaff, A. M., Liu, D., Huang, T. H., Lai, C. C., Tsai, F. J., Chang, W. C., Chen, C. H. & 7 others, Wu, T. T., Buttar, N. S., Wang, K. K. N., Wu, Y., Wang, H., Ajani, J. & Hung, M. C., Mar 20 2012, In : Cancer Cell. 21, 3, p. 374-387 14 p.

Research output: Contribution to journalArticle

210 Scopus citations
2011

A functional family-wide screening of SP/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growth

Fernandez-Zapico, M. E., Lomberk, G. A., Tsuji, S., DeMars, C. J., Bardsley, M. R., Lin, Y. H., Almada, L. L., Han, J. J., Mukhopadhyay, D., Ordog, T., Buttar, N. S. & Urrutia, R., Apr 15 2011, In : Biochemical Journal. 435, 2, p. 529-537 9 p.

Research output: Contribution to journalArticle

51 Scopus citations

Disruption of a novel krüppel-like transcription factor p300-regulated pathway for insulin biosynthesis revealed by studies of the c.-331 INS mutation found in neonatal diabetes mellitus

Bonnefond, A., Lomberk, G., Buttar, N. S., Busiah, K., Vaillant, E., Lobbens, S., Yengo, L., Dechaume, A., Mignot, B., Simon, A., Scharfmann, R., Neve, B., Tanyolaç, S., Hodoglugil, U., Pattou, F., Cavé, H., Iovanna, J., Stein, R., Polak, M., Vaxillaire, M. & 2 others, Froguel, P. & Urrutia, R., Aug 12 2011, In : Journal of Biological Chemistry. 286, 32, p. 28414-28424 11 p.

Research output: Contribution to journalArticle

52 Scopus citations

Endoscopic Evaluation and Advanced Imaging of Barrett's Esophagus

Wang, K. K. N., Okoro, N., Iyer, P. G., WongKeeSong, M., Buttar, N. S. & Tian, J., Jan 2011, In : Gastrointestinal Endoscopy Clinics of North America. 21, 1, p. 39-51 13 p.

Research output: Contribution to journalArticle

14 Scopus citations
2010

Combinatorial chemoprevention reveals a novel smoothened-independent role of GLI1 in esophageal carcinogenesis

Rizvi, S., DeMars, C. J., Comba, A., Gainullin, V. G., Rizvi, Z., Almada, L. L., Wang, K. K. N., Lomberk, G., Fernandez-Zapico, M. E. & Buttar, N. S., Sep 1 2010, In : Cancer Research. 70, 17, p. 6787-6796 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

Distinct role of kruppel-like factor 11 in the regulation of prostaglandin E2 biosynthesis

Buttar, N. S., DeMars, C. J., Lomberk, G., Rizvi, S., Bonilla-Velez, J., Achra, S., Rashtak, S., Wang, K. K. N., Fernandez-Zapico, M. E. & Urrutia, R., Apr 9 2010, In : Journal of Biological Chemistry. 285, 15, p. 11433-11444 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Molecular determinants of metaplastic and neoplastic transformation in the esophageal epithelium

Singh, A., Demars, C. & Buttar, N. S., 2010, In : Progress in Molecular Biology and Translational Science. 96, C, p. 63-92 30 p.

Research output: Contribution to journalArticle

Prevalence and predictors of recurrent neoplasia after ablation of Barrett's esophagus

Badreddine, R. J., Iyer, P. G., Wang, K. K. N., Wong Kee Song, L. M., Buttar, N. S., Dunagan, K. T., Lutzke, L. S. & Borkenhagen, L. S., Apr 2010, In : Gastrointestinal Endoscopy. 71, 4, p. 697-703 7 p.

Research output: Contribution to journalArticle

44 Scopus citations

Prognostic biomarkers for esophageal adenocarcinoma identified by analysis of tumor transcriptome

Kim, S. M., Park, Y. Y., Park, E. S., Cho, J. Y., Izzo, J. G., Zhang, D., Kim, S. B., Lee, J. H., Bhutani, M. S., Swisher, S. G., Wu, X., Coombes, K. R., Maru, D., Wang, K. K. N., Buttar, N. S., Ajani, J. A. & Lee, J. S., 2010, In : PLoS One. 5, 11, e15074.

Research output: Contribution to journalArticle

81 Scopus citations
2009

Chemoprevention in Barrett esophagus

Buttar, N. S., Oct 2009, In : Gastroenterology and Hepatology. 5, 10, p. 685-687 3 p.

Research output: Contribution to journalArticle

Endoscopic and Surgical Treatment of Mucosal (T1a) Esophageal Adenocarcinoma in Barrett's Esophagus

Iyer, P. G., Wu, T. T., Wigle, D. A., Buttar, N. S., Wongkeesong, L. M., Dunagan, K. T., Lutzke, L. S., Borkenhagen, L. S. & Wang, K. K. N., Sep 2009, In : Gastroenterology. 137, 3, p. 815-823 9 p.

Research output: Contribution to journalArticle

230 Scopus citations

Krüppel-like factor proteins and chromatin dynamics

Buttar, N. S., Lomberk, G. A., Daftary, G. S. & Urrutia, R. A., 2009, The Biology of Krüppel-like Factors. Springer Japan, p. 33-49 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
2008

Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma

Yen, C. J., Izzo, J. G., Lee, D. F., Guha, S., Wei, Y., Wu, T. T., Chen, C. T., Kuo, H. P., Hsu, J. M., Sun, H. L., Chou, C. K., Buttar, N. S., Wang, K. K. N., Huang, P., Ajani, J. & Hung, M. C., Apr 15 2008, In : Cancer Research. 68, 8, p. 2632-2640 9 p.

Research output: Contribution to journalArticle

46 Scopus citations

Correlation of histology with biomarker status after photodynamic therapy in barrett esophagus

Iyer, P. G., Wang, K. K. N., Halling, K. C., Buttar, N. S., Wongkeesong, L. M., Zinsmeister, A. R., Brankley, S. M., Westra, W. M., Lutzke, L. S., Borkenhagen, L. S. & Dunagan, K., Aug 1 2008, In : Cancer. 113, 3, p. 470-476 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Photodynamic therapy for Barrett's esophagus: Does light still have a role?

Wang, K. K. N., Lutzke, L., Borkenhagen, L., Westra, W., Song, M. W. K., Iyer, P. G. & Buttar, N. S., Dec 2008, In : Endoscopy. 40, 12, p. 1021-1025 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

Utility of Biomarkers in Prediction of Response to Ablative Therapy in Barrett's Esophagus

Iyer, P. G., Wang, K. K. N., Halling, K. C., Buttar, N. S., Wongkeesong, L. M., Zinsmeister, A. R., Brankley, S. M., Fritcher, E. G. B., Westra, W. M., Krishnadath, K. K., Lutzke, L. S. & Borkenhagen, L. S., Aug 2008, In : Gastroenterology. 135, 2, p. 370-379 10 p.

Research output: Contribution to journalArticle

61 Scopus citations
2007

Ablation of Barrett's Esophagus with Laser and Photodynamic Therapy

Wang, K. K. N. & Buttar, N. S., Oct 25 2007, Barrett's Esophagus and Esophageal Adenocarcinoma: Second Edition. Blackwell Publishing Ltd, p. 196-205 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

An ex vivo readout for evaluation of dendritic cell-induced autologous cytotoxic T lymphocyte responses against esophageal cancer

Milano, F., Rygiel, A. M., Buttar, N. S., Bergman, J. J. G. H. M., Sondermeijer, C., Van Baal, J. W. P. M., Ten Brinke, A., Kapsenberg, M., Van Ham, S. M., Peppelenbosch, M. P. & Krishnadath, K. K., Dec 2007, In : Cancer Immunology, Immunotherapy. 56, 12, p. 1967-1977 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Bone Morphogenetic Protein 4 Expressed in Esophagitis Induces a Columnar Phenotype in Esophageal Squamous Cells

Milano, F., van Baal, J. W. P. M., Buttar, N. S., Rygiel, A. M., de Kort, F., DeMars, C. J., Rosmolen, W. D., Bergman, J. J. G. H. M., van Marle, J., Wang, K. K. N., Peppelenbosch, M. P. & Krishnadath, K. K., Jun 2007, In : Gastroenterology. 132, 7, p. 2412-2421 10 p.

Research output: Contribution to journalArticle

116 Scopus citations

Chemoprevention in barrett's esophagus

Ilyas, S., Demars, C. J. & Buttar, N. S., Jan 2007, In : Journal of Gastrointestinal Cancer. 38, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

COX-2 induction by unconjugated bile acids involves reactive oxygen species-mediated signalling pathways in Barrett's oesophagus and oesophageal adenocarcinoma

Song, S., Guha, S., Liu, K., Buttar, N. S. & Bresalier, R. S., Nov 2007, In : Gut. 56, 11, p. 1512-1521 10 p.

Research output: Contribution to journalArticle

78 Scopus citations

Factors Associated With Increased Survival After Photodynamic Therapy for Cholangiocarcinoma

Iyer, P. G., Wang, K. K. N., Baron, T. H., Buttar, N. S., Wongkeesong, L. M., Roberts, L. R., LeRoy, A. J., Lutzke, L. S. & Borkenhagen, L. S., Jun 2007, In : Clinical Gastroenterology and Hepatology. 5, 6, p. 743-748 6 p.

Research output: Contribution to journalArticle

49 Scopus citations

Long-Term Survival Following Endoscopic and Surgical Treatment of High-Grade Dysplasia in Barrett's Esophagus

Iyer, P. G., Wang, K. K. N., Buttar, N. S., Wongkeesong, L. M., Krishnadath, K. K., Nichols, F. C., Lutzke, L. S. & Borkenhagen, L. S., Apr 2007, In : Gastroenterology. 132, 4, p. 1226-1233 8 p.

Research output: Contribution to journalArticle

213 Scopus citations

Predictors of stricture formation after photodynamic therapy for high-grade dysplasia in Barrett's esophagus{A figure is presented}

Iyer, P. G., Wang, K. K. N., Buttar, N. S., Wongkeesong, L. M., Lutzke, L. S. & Borkenhagen, L. S., Jan 2007, In : Gastrointestinal Endoscopy. 65, 1, p. 60-66 7 p.

Research output: Contribution to journalArticle

71 Scopus citations

Significance of neoplastic involvement of margins obtained by endoscopic mucosal resection in Barrett's esophagus

Iyer, P. G., Buttar, N. S., Wongkeesong, L. M., Lewis, J. T., Sanderson, S. O., Lutzke, L. S., Borkenhagen, L. S. & Wang, K. K. N., Nov 2007, In : American Journal of Gastroenterology. 102, 11, p. 2380-2386 7 p.

Research output: Contribution to journalArticle

64 Scopus citations
2006

Frozen section analysis of esophageal endoscopic mucosal resection specimens in the real-time management of Barrett's esophagus

Iyer, P. G., Wang, K. K. N., Lutzke, L. S., Lewis, J. T., Sanderson, S. O., Buttar, N. S., Wong Kee Song, L. M., Borkenhagen, L. S. & Burgart, L. J., Feb 2006, In : Clinical Gastroenterology and Hepatology. 4, 2, p. 173-178 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Frozen section analysis of esophageal endoscopic mucosal resection specimens in the real-time management of Barrett's esophagus

Iyer, P. G., Wang, K. K. N., Lutzke, L. S., Lewis, J. T., Sanderson, S. O., Buttar, N. S., Wong Kee Song, L. M., Borkenhagen, L. S. & Burgart, L. J., Feb 2006, In : Clinical Gastroenterology and Hepatology. 4, 2, p. 119-120 2 p.

Research output: Contribution to journalArticle

11 Scopus citations

Rodent endosonography to monitor esophageal cancer

Buttar, N. S., Wiersema, M. J., Wang, K. K. N., DeMars, C. J., Iyer, P. G. & Lutzke, L. S., Jun 2006, In : International Journal of Gastrointestinal Cancer. 37, 2-3, p. 84-90 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
2005
37 Scopus citations
68 Scopus citations

Direct percutaneous endoscopic jejunostomy: Outcomes in 307 consecutive attempts

Maple, J. T., Petersen, B. T., Baron, T. H., Gostout, C. J., Wong Kee Song, L. M. & Buttar, N. S., Dec 2005, In : American Journal of Gastroenterology. 100, 12, p. 2681-2688 8 p.

Research output: Contribution to journalArticle

119 Scopus citations
2004
52 Scopus citations
2003

Combined endoscopic mucosal resection and photodynamic therapy versus esophagectomy for management of early adenocarcinoma in Barrett's esophagus

Pacifico, R. J., Wang, K. K. N., Wongkeesong, L. M., Buttar, N. S. & Lutzke, L. S., Jul 1 2003, In : Clinical Gastroenterology and Hepatology. 1, 4, p. 252-257 6 p.

Research output: Contribution to journalArticle

133 Scopus citations

Effects of Telomerase Expression on Photodynamic Therapy of Barrett's Esophagus

Wang, K. K. N., Anderson, M., Buttar, N. S., WongKeeSong, M., Borkenhagen, L. & Lutzke, L., 2003, Proceedings of SPIE - The International Society for Optical Engineering. Kessel, D. (ed.). Vol. 4952. p. 82-90 9 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2002

Chemoprevention of esophageal adenocarcinoma by COX-2 inhibitors in an animal model of Barrett's esophagus

Buttar, N. S., Wang, K. K. N., Leontovich, O., Westcott, J. Y., Pacifico, R. J., Anderson, M. A., Krishnadath, K. K., Lutzke, L. S. & Burgart, L. J., 2002, In : Gastroenterology. 122, 4, p. 1101-1112 12 p.

Research output: Contribution to journalArticle

325 Scopus citations

The effect of selective cyclooxygenase-2 inhibition in Barrett's esophagus epithelium: An in vitro study

Buttar, N. S., Wang, K. K. N., Anderson, M. A., Dierkhising, R. A., Pacifico, R. J., Krishnadath, K. K. & Lutzke, L. S., Mar 20 2002, In : Journal of the National Cancer Institute. 94, 6, p. 422-429 8 p.

Research output: Contribution to journalArticle

111 Scopus citations
2001

Combined endoscopic mucosal resection and photodynamic therapy for esophageal neoplasia within Barrett's esophagus

Buttar, N. S., Wang, K. K. N., Lutzke, L. S., Krishnadath, K. K. & Anderson, M. A., Dec 2001, In : Gastrointestinal Endoscopy. 54, 6, p. 682-688 7 p.

Research output: Contribution to journalArticle

Combined endoscopic mucosal resection and photodynamic therapy for esophageal neoplasia within Barrett's esophagus

Buttar, N. S., Wang, K. K. N., Lutzke, L. S., Krishnadath, K. K. & Anderson, M. A., Jan 1 2001, In : Gastrointestinal Endoscopy. 54, 6, p. 682-688 7 p.

Research output: Contribution to journalArticle

215 Scopus citations

Contribution of Intraoperative Enteroscopy in the Management of Obscure Gastrointestinal Bleeding

Kendrick, M. L., Buttar, N. S., Anderson, M. A., Lutzke, L. S., Peia, D., Wang, K. K. N. & Sarr, M. G., Mar 2001, In : Journal of Gastrointestinal Surgery. 5, 2, p. 162-167 6 p.

Research output: Contribution to journalArticle

48 Scopus citations

Extent of high-grade dysplasia in Barrett's esophagus correlates with risk of adenocarcinoma

Buttar, N. S., Wang, K. K. N., Sebo, T. J., Riehle, D. M., Krishnadath, K. K., Lutzke, L. S., Anderson, M. A., Petterson, T. M. & Burgart, L. J., 2001, In : Gastroenterology. 120, 7, p. 1630-1639 10 p.

Research output: Contribution to journalArticle

373 Scopus citations

Pathogenesis of gastroesophageal reflux and Barrett esophagus

Buttar, N. S. & Falk, G. W., 2001, In : Mayo Clinic Proceedings. 76, 2, p. 226-234 9 p.

Research output: Contribution to journalArticle

41 Scopus citations
2000

Endoscopic mucosal resection

Wang, K. K. N., Buttar, N. S. & Lutzke, L., Oct 2000, In : Techniques in Gastrointestinal Endoscopy. 2, 4, p. 209-213 5 p.

Research output: Contribution to journalArticle

3 Scopus citations