Nathan W Cummins, MD

  • 582 Citations
  • 14 Scopus h-Index
20082020

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23rd conference on retroviruses and opportunistic infections (CROI 2016) Boston, Massachusetts, USA - February 22-25, 2016

Rizza, S., Cummins, N. W., Hoffman-Therry, M. & Temesgen, Z., Mar 1 2016, In : Drugs of the Future. 41, 3, p. 203-212 10 p.

Research output: Contribution to journalArticle

An advanced BLT-humanized mouse model for extended HIV-1 cure studies

Lavender, K. J., Pace, C., Sutter, K., Messer, R. J., Pouncey, D. L., Cummins, N. W., Natesampillai, S., Zheng, J., Goldsmith, J., Widera, M., Van Dis, E. S., Phillips, K., Race, B., Dittmer, U., Kukolj, G. & Hasenkrug, K. J., Jan 2 2018, In : AIDS. 32, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Both HIV-Infected and uninfected cells express TRAILshort, which confers TRAIL resistance upon bystander cells within the microenvironment

Nie, Z., Aboulnasr, F., Natesampillai, S., Burke, S. P., Krogman, A., Bren, G. D., Chung, T. D. Y., Anderson, J. R., Smart, M. K., Katzmann, D. J., Rajagopalan, G., Cummins, N. W. & Badley, A. D., Feb 1 2018, In : Journal of Immunology. 200, 3, p. 1110-1123 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Can HIV be cured and should we try?

Cummins, N. W. & Badley, A. D., Jun 1 2015, In : Mayo Clinic Proceedings. 90, 6, p. 705-709 5 p.

Research output: Contribution to journalArticle

Casp8p41 and HIV

Cummins, N. W. & Badley, A. D., 2015, In : Oncotarget. 6, 27, p. 23042-23043 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Casp8p41 expression in primary T cells induces a proinflammatory response

Taylor, J. A., Cummins, N. W., Bren, G. D., Rizza, S. A., Kolbert, C. P., Behrens, M. D., Knutson, K. L., Kahl, J. C., Asmann, Y. W. & Badley, A. D., Jun 1 2010, In : AIDS. 24, 9, p. 1251-1258 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation

Sainski, A. M., Dai, H., Natesampillai, S., Pang, Y. P., Bren, G. D., Cummins, N. W., Correia, C., Meng, X. W., Tarara, J. E., Ramirez-Alvarado, M., Katzmann, D. J., Ochsenbauer, C., Kappes, J. C., Kaufmann, S. H. & Badley, A. D., Jan 1 2014, In : Journal of Cell Biology. 206, 7, p. 867-876 10 p.

Research output: Contribution to journalArticle

19 Scopus citations
44 Scopus citations

Epidemiology, risk factors, and outcomes of infections in patients undergoing liver transplantation for hilar cholangiocarcinoma

Ramanan, P., Cummins, N. W., Wilhelm, M. P., Heimbach, J. K., Dierkhising, R., Kremers, W. K., Rosen, C. B., Gores, G. J. & Razonable, R. R., 2017, (Accepted/In press) In : Clinical Transplantation.

Research output: Contribution to journalArticle

3 Scopus citations

Extensive virologic and immunologic characterization in an HIV-infected individual following allogeneic stem cell transplant and analytic cessation of antiretroviral therapy: A case study

Cummins, N. W., Rizza, S., Litzow, M. R., Hua, S., Lee, G. Q., Einkauf, K., Chun, T. W., Rhame, F., Baker, J. V., Busch, M. P., Chomont, N., Dean, P. G., Fromentin, R., Haase, A. T., Hampton, D., Keating, S. M., Lada, S. M., Lee, T. H., Natesampillai, S., Richman, D. D. & 7 others, Schacker, T. W., Wietgrefe, S., Yu, X. G., Yao, J. D., Zeuli, J., Lichterfeld, M. & Badley, A. D., Nov 1 2017, In : PLoS Medicine. 14, 11, e1002461.

Research output: Contribution to journalArticle

20 Scopus citations

Fever and cardiac arrest in a patient with a left ventricular assist device

Tan, E. M., Marcelin, J. R., Tande, A. J., Rizza, S. & Cummins, N. W., 2015, In : Open Forum Infectious Diseases. 2, 2, ofv033.

Research output: Contribution to journalArticle

Heme oxygenase-1 regulates the immune response to influenza virus infection and vaccination in aged mice

Cummins, N. W., Weaver, E. A., May, S. M., Croatt, A. J., Foreman, O., Kennedy, R. B., Poland, G. A., Barry, M. A., Nath, K. A. & Badley, A. D., Jul 1 2012, In : FASEB Journal. 26, 7, p. 2911-2918 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

HIV elite control is associated with reduced TRAILshort expression

Paim, A. C., Cummins, N. W., Natesampillai, S., Garcia-Rivera, E., Kogan, N., Neogi, U., Sönnerborg, A., Sperk, M., Bren, G. D., Deeks, S., Polley, E. & Badley, A. D., Sep 1 2019, In : AIDS. 33, 11, p. 1757-1763 7 p.

Research output: Contribution to journalArticle

HIV protease-generated Casp8p41, when bound and inactivated by Bcl2, is degraded by the proteasome

Natesampillai, S., Cummins, N. W., Nie, Z., Sampath, R., Baker, J. V., Henry, K., Pinzone, M., O'Doherty, U., Polley, E., Bren, G. D., Katzmann, D. J. & Badley, A. D., Jul 1 2018, In : Journal of Virology. 92, 13, e00037-18.

Research output: Contribution to journalArticle

4 Scopus citations

HIV replication alters the composition of extrinsic pathway coagulation factors and increases thrombin generation.

Baker, J. V., Brummel-Ziedins, K., Neuhaus, J., Duprez, D., Cummins, N., Dalmau, D., DeHovitz, J., Lehmann, C., Sullivan, A., Woolley, I., Kuller, L., Neaton, J. D., Tracy, R. P. & INSIGHT SMART Study Team, SMART. S. T., Aug 2013, In : Journal of the American Heart Association. 2, 4, p. e000264

Research output: Contribution to journalArticle

Open Access
31 Scopus citations

Human immunodeficiency virus envelope protein Gp120 induces proliferation but not apoptosis in osteoblasts at physiologic concentrations

Cummins, N. W., Klicpera, A., Sainski, A. M., Bren, G. D., Khosla, S., Westendorf, J. J. & Badley, A. D., Sep 12 2011, In : PloS one. 6, 9, e24876.

Research output: Contribution to journalArticle

6 Scopus citations

Increasing procaspase 8 expression using repurposed drugs to induce HIV infected cell death in ex vivo patient cells

Sampath, R., Cummins, N. W., Natesampillai, S., Bren, G. D., Chung, T. D., Baker, J., Henry, K., Pagliuzza, A. & Badley, A. D., Jun 1 2017, In : PLoS One. 12, 6, e0179327.

Research output: Contribution to journalArticle

2 Scopus citations

Infected cell killing by HIV-1 protease promotes NF-κB dependent HIV-1 replication

Bren, G. D., Whitman, J., Cummins, N., Shepard, B., Rizz, S. A., Trushin, S. A. & Badley, A. D., May 7 2008, In : PloS one. 3, 5, e2112.

Research output: Contribution to journalArticle

22 Scopus citations

Intracellular Casp8p41 content is inversely associated with CD4 T cell count

Cummins, N. W., Jiang, W., McGinty, J., Bren, G. D., Bosch, R. J., Landay, A., Deeks, S. G., Martin, J. N., Douek, D., Lederman, M. M., Brenchley, J. & Badley, A. D., Aug 1 2010, In : Journal of Infectious Diseases. 202, 3, p. 386-391 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Investigation of Efavirenz Discontinuation in Multi-ethnic Populations of HIV-positive Individuals by Genetic Analysis

Cummins, N. W., Neuhaus, J., Chu, H., Neaton, J., Wyen, C., Rockstroh, J. K., Skiest, D. J., Boyd, M. A., Khoo, S., Rotger, M., Telenti, A., Weinshilboum, R. M. & Badley, A. D., Jul 1 2015, In : EBioMedicine. 2, 7, p. 706-712 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Is abnormal urine protein/osmolality ratio associated with abnormal renal function in patients receiving tenofovir disoproxil fumarate?

Marcelin, J. R., Berg, M. L., Tan, E. M., Amer, H., Cummins, N. W. & Rizza, S., Feb 1 2016, In : PLoS One. 11, 2, e0149562.

Research output: Contribution to journalArticle

Isolation of a TRAIL antagonist from the serum of HIV-infected patients

Schnepple, D. J., Shepard, B., Bren, G. D., Cummins, N. W., Natesampillai, S., Trushin, S., Algeciras-Schimnich, A., Meng, X. W., Sainski, A. M., Rizza, S. A., Kaufmann, S. H. & Badley, A. D., Oct 14 2011, In : Journal of Biological Chemistry. 286, 41, p. 35742-35754 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Lysinibacillus massiliensis panniculitis masquerading as erythema nodosum: A case report

Jin, J. J., Keith, P. J., Cummins, N. W., Kane, S. V., Pritt, B. S. & Sanchez, J. L., Mar 1 2017, In : Open Forum Infectious Diseases. 4, 2, ofx072.

Research output: Contribution to journalArticle

Maintenance of the HIV reservoir is antagonized by selective BCL2 inhibition

Cummins, N. W., Sainski-Nguyen, A. M., Natesampillai, S., Aboulnasr, F., Kaufmann, S. H. & Badley, A. D., Jun 1 2017, In : Journal of Virology. 91, 11, e00012-17.

Research output: Contribution to journalArticle

21 Scopus citations

Multiple pyogenic liver abscesses caused by Eggerthella lenta treated with ertapenem: A case report

Elias, R. M., Khoo, S. Y., Pupaibool, J., Nienaber, J. H. & Cummins, N. W., Jan 1 2012, In : Case Reports in Medicine. 2012, 718130.

Research output: Contribution to journalArticle

3 Scopus citations

Patients with discordant responses to antiretroviral therapy have impaired killing of HIV-infected T cells

Natesampillai, S., Nie, Z., Cummins, N. W., Jochmans, D., Bren, G. D., Angel, J. B. & Badley, A. D., Nov 1 2010, In : PLoS pathogens. 6, 11, e1001213.

Research output: Contribution to journalArticle

12 Scopus citations
5 Scopus citations

Prime, shock, and kill: Priming CD4 T cells from HIV patients with a BCL-2 antagonist before HIV reactivation reduces HIV reservoir size

Cummins, N. W., Sainski, A. M., Dai, H., Natesampillai, S., Pang, Y-P., Bren, G. D., De Araujo Correia, M. C. M., Sampath, R., Rizza, S., O'Brien, D., Yao, J. D., Kaufmann, S. H. & Badley, A. D., Apr 1 2016, In : Journal of Virology. 90, 8, p. 4032-4048 17 p.

Research output: Contribution to journalArticle

39 Scopus citations

Risk of suicidal behavior with use of efavirenz: Results from the strategic timing of antiretroviral treatment trial

Arenas-Pinto, A., Grund, B., Sharma, S., Martinez, E., Cummins, N. W., Fox, J., Klingman, K. L., Sedlacek, D., Collins, S., Flynn, P. M., Chasanov, W. M., Kedem, E., Katlama, C., Sierra-Madero, J., Afonso, C., Brouwers, P. & Cooper, D. A., Jul 18 2018, In : Clinical Infectious Diseases. 67, 3, p. 420-429 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Short communication: CD4 T cell declines occurring during suppressive antiretroviral therapy reflect continued production of Casp8p41

Cummins, N. W., Neuhaus, J., Sainski, A. M., Strausbauch, M. A., Wettstein, P. J., Lewin, S. R., Plana, M., Rizza, S. A., Temesgen, Z., Touloumi, G., Freiberg, M., Neaton, J. & Badley, A. D., May 30 2014, In : AIDS Research and Human Retroviruses. 30, 5, p. 476-479 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Stability in the cumulative incidence, severity and mortality of 101 cases of invasive mucormycosis in high-risk patients from 1995 to 2011: A comparison of eras immediately before and after the availability of voriconazole and echinocandin-amphotericin combination therapies

Abidi, M. Z., Sohail, M. R., Cummins, N., Wilhelm, M., Wengenack, N., Brumble, L., Shah, H., Jane Hata, D., Mccullough, A., Wendel, A., Vikram, H. R., Kusne, S., Litzow, M., Letendre, L., Lahr, B. D., Poeschla, E. & Walker, R. C., Nov 1 2014, In : Mycoses. 57, 11, p. 687-698 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

The Association between Serum Biomarkers and Disease Outcome in Influenza A(H1N1)pdm09 Virus Infection: Results of Two International Observational Cohort Studies

Davey, R. T., Lynfield, R., Dwyer, D. E., Losso, M. H., Cozzi-Lepri, A., Wentworth, D., Lane, H. C., Dewar, R., Rupert, A., Metcalf, J. A., Pett, S. L., Uyeki, T. M., Bruguera, J. M., Angus, B., Cummins, N., Lundgren, J. & Neaton, J. D., Feb 27 2013, In : PloS one. 8, 2, e57121.

Research output: Contribution to journalArticle

23 Scopus citations

The HIV-1-specific protein Casp8p41 induces death of infected cells through Bax/Bak

Sainski, A. M., Natesampillai, S., Cummins, N. W., Bren, G. D., Taylor, J., Saenz, D. T., Poeschla, E. M. & Badley, A. D., Aug 2011, In : Journal of virology. 85, 16, p. 7965-7975 11 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

The role of the BCL-2 family of proteins in HIV-1 pathogenesis and persistence

Chandrasekar, A. P., Cummins, N. W. & Badleya, A. D., Jan 2020, In : Clinical Microbiology Reviews. 33, 1, e00107-19.

Research output: Contribution to journalArticle

1 Scopus citations

Trailshort protects against CD4 T cell death during acute HIV infection

Natesampillai, S., Paim, A. C., Cummins, N. W., Chandrasekar, A. P., Bren, G. D., Lewin, S. R., Kiem, H. P. & Badley, A. D., Aug 1 2019, In : Journal of Immunology. 203, 3, p. 718-724 7 p.

Research output: Contribution to journalArticle

Transient Loss of HIV-1 DNA in an HIV-1 Positive Patient After Kidney Transplantation: A Case Report

Paim, A. C., Rizza, S., Badley, A. D., Prieto, M., Taler, S. J., Chong, P. P. & Cummins, N. W., Jan 1 2018, (Accepted/In press) In : American Journal of Medicine.

Research output: Contribution to journalArticle