Research Output per year
Research Output 2008 2020
2008
21
Citations
(Scopus)
Infected cell killing by HIV-1 protease promotes NF-κB dependent HIV-1 replication
Bren, G. D., Whitman, J., Cummins, N. W., Shepard, B., Rizz, S. A., Trushin, S. A. & Badley, A. D., May 7 2008, In : PLoS One. 3, 5, e2112.Research output: Contribution to journal › Article
Caspase 8
Human immunodeficiency virus 1
T-cells
HIV-1
proteinases
2009
43
Citations
(Scopus)
Deficiency of cytomegalovirus (CMV)-specific CD8+ T cells in patients presenting with late-onset CMV disease several years after transplantation
Cummins, N. W., Deziel, P. J., Abraham, R. S. & Razonable, R. R., Feb 2009, In : Transplant Infectious Disease. 11, 1, p. 20-27 8 p.Research output: Contribution to journal › Article
Cytomegalovirus
Transplantation
T-Lymphocytes
Mental Competency
Late Onset Disorders
28
Citations
(Scopus)
The TRAIL to viral pathogenesis: The good, the bad and the ugly
Cummins, N. W. & Badley, A. D., 2009, In : Current Molecular Medicine. 9, 4, p. 495-505 11 p.Research output: Contribution to journal › Article
Virus Diseases
Antiviral Agents
Apoptosis
Viruses
Cytokines
2010
4
Citations
(Scopus)
Casp8p41 expression in primary T cells induces a proinflammatory response
Taylor, J. A., Cummins, N. W., Bren, G. D., Rizza, S., Kolbert, C. P., Behrens, M. D., Knutson, K. L., Kahl, J. C., Asmann, Y. & Badley, A. D., Jun 1 2010, In : AIDS. 24, 9, p. 1251-1258 8 p.Research output: Contribution to journal › Article
HIV
T-Lymphocytes
NF-kappa B
Microarray Analysis
Cytokines
16
Citations
(Scopus)
How much Gp120 is there?
Cummins, N. W., Rizza, S. & Badley, A. D., Apr 15 2010, In : Journal of Infectious Diseases. 201, 8, p. 1273-1274 2 p.Research output: Contribution to journal › Article
HIV Envelope Protein gp120
Lymphoid Tissue
Tissue Distribution
HIV Infections
11
Citations
(Scopus)
Intracellular Casp8p41 content is inversely associated with CD4 T cell count
Cummins, N. W., Jiang, W., McGinty, J., Bren, G. D., Bosch, R. J., Landay, A., Deeks, S. G., Martin, J. N., Douek, D., Lederman, M. M., Brenchley, J. & Badley, A. D., Aug 1 2010, In : Journal of Infectious Diseases. 202, 3, p. 386-391 6 p.Research output: Contribution to journal › Article
CD4 Lymphocyte Count
T-Lymphocytes
HIV
Bacterial DNA
Caspase 8
119
Citations
(Scopus)
Mechanisms of HIV-associated lymphocyte apoptosis: 2010
Cummins, N. W. & Badley, A. D., Nov 2010, In : Cell Death and Disease. 1, 11, e99.Research output: Contribution to journal › Article
Virus Diseases
HIV
Lymphocytes
Apoptosis
Viral Proteins
12
Citations
(Scopus)
Patients with discordant responses to antiretroviral therapy have impaired killing of HIV-infected T cells
Natesampillai, S., Nie, Z., Cummins, N. W., Jochmans, D., Bren, G. D., Angel, J. B. & Badley, A. D., Nov 2010, In : PLoS Pathogens. 6, 11, e1001213.Research output: Contribution to journal › Article
HIV Protease
HIV
Cell Death
T-Lymphocytes
Peptide Hydrolases
5
Citations
(Scopus)
Polymorphism in tumor necrosis factor-related apoptosis-inducing ligand receptor 1 is associated with poor viral response to interferon-based hepatitis C virus therapy in HIV/hepatitis C virus-coinfected individuals
Rizza, S., Cummins, N. W., Rider, D. N., Saeed, S., Klein, M. B. & Badley, A. D., Nov 13 2010, In : AIDS. 24, 17, p. 2637-2644 8 p.Research output: Contribution to journal › Article
Hepacivirus
Interferons
Tumor Necrosis Factor-alpha
HIV
Apoptosis
2011
6
Citations
(Scopus)
Human immunodeficiency virus envelope protein Gp120 induces proliferation but not apoptosis in osteoblasts at physiologic concentrations
Cummins, N. W., Klicpera, A., Sainski, A. M., Bren, G. D., Khosla, S., Westendorf, J. J. & Badley, A. D., Sep 12 2011, In : PLoS One. 6, 9, e24876.Research output: Contribution to journal › Article
Human Immunodeficiency Virus env Gene Products
osteoblasts
Osteoblasts
Human immunodeficiency virus
apoptosis
10
Citations
(Scopus)
Isolation of a TRAIL antagonist from the serum of HIV-infected patients
Schnepple, D. J., Shepard, B., Bren, G. D., Cummins, N. W., Natesampillai, S., Trushin, S., Algeciras-Schimnich, A., Meng, X. W., Sainski, A. M., Rizza, S., Kaufmann, S. H. & Badley, A. D., Oct 14 2011, In : Journal of Biological Chemistry. 286, 41, p. 35742-35754 13 p.Research output: Contribution to journal › Article
TNF-Related Apoptosis-Inducing Ligand
HIV
Serum
TNF-Related Apoptosis-Inducing Ligand Receptors
HIV Infections
15
Citations
(Scopus)
The HIV-1-specific protein Casp8p41 induces death of infected cells through Bax/Bak
Sainski, A. M., Natesampillai, S., Cummins, N. W., Bren, G. D., Taylor, J., Saenz, D. T., Poeschla, E. M. & Badley, A. D., Aug 2011, In : Journal of Virology. 85, 16, p. 7965-7975 11 p.Research output: Contribution to journal › Article
Human immunodeficiency virus 1
caspase-9
HIV-1
cell death
Cell Death
2012
25
Citations
(Scopus)
Heme oxygenase-1 regulates the immune response to influenza virus infection and vaccination in aged mice
Cummins, N. W., Weaver, E. A., May, S. M., Croatt, A. J., Foreman, O., Kennedy, R. B., Poland, G. A., Barry, M. A., Nath, K. A. & Badley, A. D., Jul 2012, In : FASEB Journal. 26, 7, p. 2911-2918 8 p.Research output: Contribution to journal › Article
Heme Oxygenase-1
Virus Diseases
Orthomyxoviridae
Viruses
Vaccination
3
Citations
(Scopus)
Multiple pyogenic liver abscesses caused by Eggerthella lenta treated with ertapenem: A case report
Elias, R. M., Khoo, S. Y., Pupaibool, J., Nienaber, J. H. & Cummins, N. W., 2012, In : Case Reports in Medicine. 2012, 718130.Research output: Contribution to journal › Article
Pyogenic Liver Abscess
Liver Abscess
Bacillus
Drainage
Infection
2013
Advances in the treatment of HIV and chronic hepatitis C virus infection: A report from the 20<sup>th</sup> conference on retroviruses and opportunistic infections (croi 2013)
Rizza, S., Cummins, N. W., El Atrouni, W., Badley, A. D., Dababneh, A. & Temesgen, Z., 2013, In : Drugs of the Future. 38, 5, p. 325-333 9 p.Research output: Contribution to journal › Article
Retroviridae Infections
Opportunistic Infections
Chronic Hepatitis C
Virus Diseases
Hepacivirus
13
Citations
(Scopus)
Anti-apoptotic mechanisms of HIV: Lessons and novel approaches to curing HIV
Cummins, N. W. & Badley, A. D., Sep 2013, In : Cellular and Molecular Life Sciences. 70, 18, p. 3355-3363 9 p.Research output: Contribution to journal › Article
HIV
Viral Cytopathogenic Effect
Cell Death
Viruses
Infection
31
Citations
(Scopus)
HIV replication alters the composition of extrinsic pathway coagulation factors and increases thrombin generation.
Baker, J. V., Brummel-Ziedins, K., Neuhaus, J., Duprez, D., Cummins, N. W., Dalmau, D., DeHovitz, J., Lehmann, C., Sullivan, A., Woolley, I., Kuller, L., Neaton, J. D., Tracy, R. P. & INSIGHT SMART Study Team, SMART. S. T., Aug 2013, In : Journal of the American Heart Association. 2, 4Research output: Contribution to journal › Article
Blood Coagulation Factors
Thrombin
HIV
Antithrombins
Therapeutics
22
Citations
(Scopus)
The Association between Serum Biomarkers and Disease Outcome in Influenza A(H1N1)pdm09 Virus Infection: Results of Two International Observational Cohort Studies
Davey, R. T., Lynfield, R., Dwyer, D. E., Losso, M. H., Cozzi-Lepri, A., Wentworth, D., Lane, H. C., Dewar, R., Rupert, A., Metcalf, J. A., Pett, S. L., Uyeki, T. M., Bruguera, J. M., Angus, B., Cummins, N. W., Lundgren, J. & Neaton, J. D., Feb 27 2013, In : PLoS One. 8, 2, e57121.Research output: Contribution to journal › Article
H1N1 Subtype Influenza A Virus
Biomarkers
Virus Diseases
cohort studies
Viruses
2014
17
Citations
(Scopus)
Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation
Sainski, A. M., Dai, H., Natesampillai, S., Pang, Y-P., Bren, G. D., Cummins, N. W., Correia, C., Meng, X. W., Tarara, J. E., Ramirez-Alvarado, M., Katzmann, D. J., Ochsenbauer, C., Kappes, J. C., Kaufmann, S. H. & Badley, A. D., 2014, In : Journal of Cell Biology. 206, 7, p. 867-876 10 p.Research output: Contribution to journal › Article
Peptide Hydrolases
HIV
T-Lymphocytes
Caspase 8
Cell Death
1
Citation
(Scopus)
Correction to Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation [Journal of Cell Biology, 206, 7, (2014), 867-876]
Sainski, A. M., Dai, H., Natesampillai, S., Pang, Y-P., Bren, G. D., Cummins, N. W., Correia, C., Wei Meng, X., Tarara, J. E., Ramirez-Alvarado, M., Katzmann, D. J., Ochsenbauer, C., Kappes, J. C., Kaufmann, S. H. & Badley, A. D., 2014, In : Journal of Cell Biology. 207, 1, p. 159 1 p.Research output: Contribution to journal › Article
HIV Protease
Cell Biology
T-Lymphocytes
CORR Insights: Is synovial C-reactive protein a useful marker for periprosthetic joint infection?
Cummins, N. W., Dec 1 2014, In : Clinical Orthopaedics and Related Research. 472, 12, p. 4004-4005 2 p.Research output: Contribution to journal › Article
Prosthesis-Related Infections
Knee Prosthesis
Inflammation Mediators
Hip Prosthesis
Knee Replacement Arthroplasties
7
Citations
(Scopus)
Short communication: CD4 T cell declines occurring during suppressive antiretroviral therapy reflect continued production of Casp8p41
Cummins, N. W., Neuhaus, J., Sainski, A. M., Strausbauch, M. A., Wettstein, P. J., Lewin, S. R., Plana, M., Rizza, S., Temesgen, Z., Touloumi, G., Freiberg, M., Neaton, J. & Badley, A. D., May 30 2014, In : AIDS Research and Human Retroviruses. 30, 5, p. 476-479 4 p.Research output: Contribution to journal › Article
Communication
T-Lymphocytes
HIV
Therapeutics
CD4 Lymphocyte Count
29
Citations
(Scopus)
Stability in the cumulative incidence, severity and mortality of 101 cases of invasive mucormycosis in high-risk patients from 1995 to 2011: A comparison of eras immediately before and after the availability of voriconazole and echinocandin-amphotericin combination therapies
Abidi, M. Z., Sohail, M. R., Cummins, N. W., Wilhelm, M., Wengenack, N., Brumble, L., Shah, H., Jane Hata, D., Mccullough, A., Wendel, A., Vikram, H. R., Kusne, S., Litzow, M. R., Letendre, L., Lahr, B. D., Poeschla, E. & Walker, R. C., Nov 1 2014, In : Mycoses. 57, 11, p. 687-698 12 p.Research output: Contribution to journal › Article
Echinocandins
Mucormycosis
Amphotericin B
Mortality
Incidence
2015
Can HIV be cured and should we try?
Cummins, N. W. & Badley, A. D., Jun 1 2015, In : Mayo Clinic Proceedings. 90, 6, p. 705-709 5 p.Research output: Contribution to journal › Article
Virus Latency
Anti-Retroviral Agents
AIDS Vaccines
Viral Load
HIV Infections
3
Citations
(Scopus)
Casp8p41 and HIV
Cummins, N. W. & Badley, A. D., 2015, In : Oncotarget. 6, 27, p. 23042-23043 2 p.Research output: Contribution to journal › Article
Viral Drug Resistance
HIV Protease
CD4-Positive T-Lymphocytes
Enzyme Activation
Caspase 9
Fever and cardiac arrest in a patient with a left ventricular assist device
Tan, E. M., Marcelin, J. R., Tande, A. J., Rizza, S. & Cummins, N. W., 2015, In : Open Forum Infectious Diseases. 2, 2, ofv033.Research output: Contribution to journal › Article
Heart-Assist Devices
Heart Arrest
Fever
Deer
Anaplasma
12
Citations
(Scopus)
Investigation of Efavirenz Discontinuation in Multi-ethnic Populations of HIV-positive Individuals by Genetic Analysis
Cummins, N. W., Neuhaus, J., Chu, H., Neaton, J., Wyen, C., Rockstroh, J. K., Skiest, D. J., Boyd, M. A., Khoo, S., Rotger, M., Telenti, A., Weinshilboum, R. M. & Badley, A. D., Jul 1 2015, In : EBioMedicine. 2, 7, p. 706-712 7 p.Research output: Contribution to journal › Article
efavirenz
HIV
Population
Cytochrome P-450 CYP3A
Polymorphism
2016
23rd conference on retroviruses and opportunistic infections (CROI 2016) Boston, Massachusetts, USA - February 22-25, 2016
Rizza, S., Cummins, N. W., Hoffman-Therry, M. & Temesgen, Z., Mar 1 2016, In : Drugs of the Future. 41, 3, p. 203-212 10 p.Research output: Contribution to journal › Article
Retroviridae Infections
Opportunistic Infections
HIV
Anti-Retroviral Agents
Administrative Personnel
Is abnormal urine protein/osmolality ratio associated with abnormal renal function in patients receiving tenofovir disoproxil fumarate?
Marcelin, J. R., Berg, M. L., Tan, E. M., Amer, H., Cummins, N. W. & Rizza, S., Feb 1 2016, In : PLoS One. 11, 2, e0149562.Research output: Contribution to journal › Article
Tenofovir
renal function
osmolality
Osmolar Concentration
urine
34
Citations
(Scopus)
Prime, shock, and kill: Priming CD4 T cells from HIV patients with a BCL-2 antagonist before HIV reactivation reduces HIV reservoir size
Cummins, N. W., Sainski, A. M., Dai, H., Natesampillai, S., Pang, Y-P., Bren, G. D., De Araujo Correia, M. C. M., Sampath, R., Rizza, S., O'Brien, D., Yao, J. D., Kaufmann, S. H. & Badley, A. D., Apr 1 2016, In : Journal of Virology. 90, 8, p. 4032-4048 17 p.Research output: Contribution to journal › Article
antagonists
Shock
T-lymphocytes
HIV
T-Lymphocytes
2017
3
Citations
(Scopus)
Epidemiology, risk factors, and outcomes of infections in patients undergoing liver transplantation for hilar cholangiocarcinoma
Ramanan, P., Cummins, N. W., Wilhelm, M. P., Heimbach, J. K., Dierkhising, R., Kremers, W. K., Rosen, C. B., Gores, G. J. & Razonable, R. R., 2017, (Accepted/In press) In : Clinical Transplantation.Research output: Contribution to journal › Article
Klatskin Tumor
Liver Transplantation
Epidemiology
Infection
Pathologic Constriction
19
Citations
(Scopus)
Extensive virologic and immunologic characterization in an HIV-infected individual following allogeneic stem cell transplant and analytic cessation of antiretroviral therapy: A case study
Cummins, N. W., Rizza, S., Litzow, M. R., Hua, S., Lee, G. Q., Einkauf, K., Chun, T. W., Rhame, F., Baker, J. V., Busch, M. P., Chomont, N., Dean, P. G., Fromentin, R., Haase, A. T., Hampton, D., Keating, S. M., Lada, S. M., Lee, T. H., Natesampillai, S., Richman, D. D. & 7 others, , Nov 1 2017, In : PLoS Medicine. 14, 11, e1002461.Research output: Contribution to journal › Article
HIV-1
Stem Cells
HIV
Transplants
Stem Cell Transplantation
Increasing procaspase 8 expression using repurposed drugs to induce HIV infected cell death in ex vivo patient cells
Sampath, R., Cummins, N. W., Natesampillai, S., Bren, G. D., Chung, T. D., Baker, J., Henry, K., Pagliuzza, A. & Badley, A. D., Jun 1 2017, In : PLoS One. 12, 6, e0179327.Research output: Contribution to journal › Article
Drug Repositioning
Caspase 8
Cell death
cell death
Cell Death
Lysinibacillus massiliensis panniculitis masquerading as erythema nodosum: A case report
Jin, J. J., Keith, P. J., Cummins, N. W., Kane, S. V., Pritt, B. S. & Sanchez, J. L., Mar 1 2017, In : Open Forum Infectious Diseases. 4, 2, ofx072.Research output: Contribution to journal › Article
Panniculitis
Erythema Nodosum
Bacillus
Crohn Disease
Sepsis
17
Citations
(Scopus)
Maintenance of the HIV reservoir is antagonized by selective BCL2 inhibition
Cummins, N. W., Sainski-Nguyen, A. M., Natesampillai, S., Aboulnasr, F., Kaufmann, S. H. & Badley, A. D., Jun 1 2017, In : Journal of Virology. 91, 11, e00012-17.Research output: Contribution to journal › Article
Maintenance
HIV
cells
Infection
deterioration
2018
11
Citations
(Scopus)
An advanced BLT-humanized mouse model for extended HIV-1 cure studies
Lavender, K. J., Pace, C., Sutter, K., Messer, R. J., Pouncey, D. L., Cummins, N. W., Natesampillai, S., Zheng, J., Goldsmith, J., Widera, M., Van Dis, E. S., Phillips, K., Race, B., Dittmer, U., Kukolj, G. & Hasenkrug, K. J., Jan 2 2018, In : AIDS. 32, 1, p. 1-10 10 p.Research output: Contribution to journal › Article
Thymus Gland
HIV-1
Bone Marrow
Liver
Therapeutics
5
Citations
(Scopus)
Both HIV-Infected and uninfected cells express TRAILshort, which confers TRAIL resistance upon bystander cells within the microenvironment
Nie, Z., Aboulnasr, F., Natesampillai, S., Burke, S. P., Krogman, A., Bren, G. D., Chung, T. D. Y., Anderson, J. R., Smart, M. K., Katzmann, D. J., Rajagopalan, G., Cummins, N. W. & Badley, A. D., Feb 1 2018, In : Journal of Immunology. 200, 3, p. 1110-1123 14 p.Research output: Contribution to journal › Article
TNF-Related Apoptosis-Inducing Ligand
Cellular Microenvironment
HIV
TNF-Related Apoptosis-Inducing Ligand Receptors
Proteasome Endopeptidase Complex
3
Citations
(Scopus)
HIV protease-generated Casp8p41, when bound and inactivated by Bcl2, is degraded by the proteasome
Natesampillai, S., Cummins, N. W., Nie, Z., Sampath, R., Baker, J. V., Henry, K., Pinzone, M., O'Doherty, U., Polley, E., Bren, G. D., Katzmann, D. J. & Badley, A. D., Jul 1 2018, In : Journal of Virology. 92, 13, e00037-18.Research output: Contribution to journal › Article
HIV Protease
proteasome endopeptidase complex
Proteasome Endopeptidase Complex
cell death
Cell Death
4
Citations
(Scopus)
Risk of suicidal behavior with use of efavirenz: Results from the strategic timing of antiretroviral treatment trial
Arenas-Pinto, A., Grund, B., Sharma, S., Martinez, E., Cummins, N. W., Fox, J., Klingman, K. L., Sedlacek, D., Collins, S., Flynn, P. M., Chasanov, W. M., Kedem, E., Katlama, C., Sierra-Madero, J., Afonso, C., Brouwers, P. & Cooper, D. A., Jul 18 2018, In : Clinical Infectious Diseases. 67, 3, p. 420-429 10 p.Research output: Contribution to journal › Article
efavirenz
Risk-Taking
Mental Disorders
Group Psychotherapy
Therapeutics
Transient Loss of HIV-1 DNA in an HIV-1 Positive Patient After Kidney Transplantation: A Case Report
Paim, A. C., Rizza, S., Badley, A. D., Prieto, M., Taler, S. J., Chong, P. P. & Cummins, N. W., Jan 1 2018, (Accepted/In press) In : American Journal of Medicine.Research output: Contribution to journal › Article
Kidney Transplantation
HIV-1
DNA
2019
HIV elite control is associated with reduced TRAILshort expression
Paim, A. C., Cummins, N. W., Natesampillai, S., Garcia-Rivera, E., Kogan, N., Neogi, U., Sönnerborg, A., Sperk, M., Bren, G. D., Deeks, S., Polley, E. & Badley, A. D., Sep 1 2019, In : AIDS. 33, 11, p. 1757-1763 7 p.Research output: Contribution to journal › Article
HIV-1
HIV
Blood Cells
Cell Death
HIV Infections
Trailshort protects against CD4 T cell death during acute HIV infection
Natesampillai, S., Paim, A. C., Cummins, N. W., Chandrasekar, A. P., Bren, G. D., Lewin, S. R., Kiem, H. P. & Badley, A. D., Aug 1 2019, In : Journal of Immunology. 203, 3, p. 718-724 7 p.Research output: Contribution to journal › Article
HIV Infections
Cell Death
T-Lymphocytes
HIV-1
Clustered Regularly Interspaced Short Palindromic Repeats
2020
The role of the BCL-2 family of proteins in HIV-1 pathogenesis and persistence
Chandrasekar, A. P., Cummins, N. W. & Badleya, A. D., Jan 2020, In : Clinical Microbiology Reviews. 33, 1, e00107-19.Research output: Contribution to journal › Article
HIV-1
Proteins
Therapeutics
Apoptosis
Infection