Nathan W Cummins, MD

  • 617 Citations
  • 14 Scopus h-Index
20082020

Research output per year

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Research Output

2020

COVID-19 Ethics and Research

Meagher, K. M., Cummins, N. W., Bharucha, A. E., Badley, A. D., Chlan, L. L. & Wright, R. S., Jun 2020, In : Mayo Clinic proceedings. 95, 6, p. 1119-1123 5 p.

Research output: Contribution to journalShort survey

Open Access
1 Scopus citations

Mechanisms of Human Immunodeficiency Virus-Associated Lymphocyte Regulated Cell Death

Paim, A. C., Badley, A. D. & Cummins, N. W., Feb 2020, In : AIDS Research and Human Retroviruses. 36, 2, p. 101-115 15 p.

Research output: Contribution to journalReview article

The role of the BCL-2 family of proteins in HIV-1 pathogenesis and persistence

Chandrasekar, A. P., Cummins, N. W. & Badleya, A. D., Jan 2020, In : Clinical Microbiology Reviews. 33, 1, e00107-19.

Research output: Contribution to journalArticle

1 Scopus citations
2019

HIV elite control is associated with reduced TRAILshort expression

Paim, A. C., Cummins, N. W., Natesampillai, S., Garcia-Rivera, E., Kogan, N., Neogi, U., Sönnerborg, A., Sperk, M., Bren, G. D., Deeks, S., Polley, E. & Badley, A. D., Sep 1 2019, In : AIDS. 33, 11, p. 1757-1763 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Trailshort protects against CD4 T cell death during acute HIV infection

Natesampillai, S., Paim, A. C., Cummins, N. W., Chandrasekar, A. P., Bren, G. D., Lewin, S. R., Kiem, H. P. & Badley, A. D., Aug 1 2019, In : Journal of Immunology. 203, 3, p. 718-724 7 p.

Research output: Contribution to journalArticle

2018

Allogeneic stem cell transplantation alone is unlikely to provide the HIV-1 cure

Cummins, N. W. & Badley, A. D., Jan 1 2018, In : Future Virology. 13, 5, p. 307-308 2 p.

Research output: Contribution to journalEditorial

An advanced BLT-humanized mouse model for extended HIV-1 cure studies

Lavender, K. J., Pace, C., Sutter, K., Messer, R. J., Pouncey, D. L., Cummins, N. W., Natesampillai, S., Zheng, J., Goldsmith, J., Widera, M., Van Dis, E. S., Phillips, K., Race, B., Dittmer, U., Kukolj, G. & Hasenkrug, K. J., Jan 2 2018, In : AIDS. 32, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Both HIV-Infected and uninfected cells express TRAILshort, which confers TRAIL resistance upon bystander cells within the microenvironment

Nie, Z., Aboulnasr, F., Natesampillai, S., Burke, S. P., Krogman, A., Bren, G. D., Chung, T. D. Y., Anderson, J. R., Smart, M. K., Katzmann, D. J., Rajagopalan, G., Cummins, N. W. & Badley, A. D., Feb 1 2018, In : Journal of Immunology. 200, 3, p. 1110-1123 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Corrections: Both HIV-infected and uninfected cells express TRAILshort, which confers TRAIL resistance upon bystander cells within the microenvironment (Journal of Immunology (2008) 200 (1110-1123) DOI: 10.4049/jimmunol.1701113)

Nie, Z., Aboulnasr, F., Natesampillai, S., Burke, S. P., Krogman, A., Bren, G. D., Chung, T. D. Y., Anderson, J. R., Smart, M. K., Katzmann, D. J., Rajagopalan, G., Cummins, N. W. & Badley, A. D., Feb 1 2018, In : Journal of Immunology. 201, 5, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

HIV protease-generated Casp8p41, when bound and inactivated by Bcl2, is degraded by the proteasome

Natesampillai, S., Cummins, N. W., Nie, Z., Sampath, R., Baker, J. V., Henry, K., Pinzone, M., O'Doherty, U., Polley, E. C., Bren, G. D., Katzmann, D. J. & Badley, A. D., Jul 1 2018, In : Journal of virology. 92, 13, e00037-18.

Research output: Contribution to journalArticle

5 Scopus citations

Risk of suicidal behavior with use of efavirenz: Results from the strategic timing of antiretroviral treatment trial

Arenas-Pinto, A., Grund, B., Sharma, S., Martinez, E., Cummins, N., Fox, J., Klingman, K. L., Sedlacek, D., Collins, S., Flynn, P. M., Chasanov, W. M., Kedem, E., Katlama, C., Sierra-Madero, J., Afonso, C., Brouwers, P. & Cooper, D. A., Jul 18 2018, In : Clinical Infectious Diseases. 67, 3, p. 420-429 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Transient Loss of HIV-1 DNA in an HIV-1 Positive Patient After Kidney Transplantation: A Case Report

Paim, A. C., Rizza, S., Badley, A. D., Prieto, M., Taler, S. J., Chong, P. P. & Cummins, N. W., Jan 1 2018, (Accepted/In press) In : American Journal of Medicine.

Research output: Contribution to journalArticle

2017

Epidemiology, risk factors, and outcomes of infections in patients undergoing liver transplantation for hilar cholangiocarcinoma

Ramanan, P., Cummins, N. W., Wilhelm, M. P., Heimbach, J. K., Dierkhising, R., Kremers, W. K., Rosen, C. B., Gores, G. J. & Razonable, R. R., 2017, (Accepted/In press) In : Clinical Transplantation.

Research output: Contribution to journalArticle

3 Scopus citations

Extensive virologic and immunologic characterization in an HIV-infected individual following allogeneic stem cell transplant and analytic cessation of antiretroviral therapy: A case study

Cummins, N. W., Rizza, S., Litzow, M. R., Hua, S., Lee, G. Q., Einkauf, K., Chun, T. W., Rhame, F., Baker, J. V., Busch, M. P., Chomont, N., Dean, P. G., Fromentin, R., Haase, A. T., Hampton, D., Keating, S. M., Lada, S. M., Lee, T. H., Natesampillai, S., Richman, D. D. & 7 others, Schacker, T. W., Wietgrefe, S., Yu, X. G., Yao, J. D., Zeuli, J., Lichterfeld, M. & Badley, A. D., Nov 2017, In : PLoS Medicine. 14, 11, e1002461.

Research output: Contribution to journalArticle

23 Scopus citations

Increasing procaspase 8 expression using repurposed drugs to induce HIV infected cell death in ex vivo patient cells

Sampath, R., Cummins, N. W., Natesampillai, S., Bren, G. D., Chung, T. D., Baker, J., Henry, K., Pagliuzza, A. & Badley, A. D., Jun 2017, In : PloS one. 12, 6, e0179327.

Research output: Contribution to journalArticle

2 Scopus citations

Lysinibacillus massiliensis panniculitis masquerading as erythema nodosum: A case report

Jin, J. J., Keith, P. J., Cummins, N. W., Kane, S. V., Pritt, B. S. & Sanchez, J. L., Mar 1 2017, In : Open Forum Infectious Diseases. 4, 2, ofx072.

Research output: Contribution to journalArticle

Maintenance of the HIV reservoir is antagonized by selective BCL2 inhibition

Cummins, N. W., Sainski-Nguyen, A. M., Natesampillai, S., Aboulnasr, F., Kaufmann, S. H. & Badley, A. D., Jun 1 2017, In : Journal of Virology. 91, 11, e00012-17.

Research output: Contribution to journalArticle

25 Scopus citations
2016

23rd conference on retroviruses and opportunistic infections (CROI 2016) Boston, Massachusetts, USA - February 22-25, 2016

Rizza, S. A., Cummins, N., Hoffman-Therry, M. & Temesgen, Z., Mar 2016, In : Drugs of the Future. 41, 3, p. 203-212 10 p.

Research output: Contribution to journalArticle

Casp8p41: The protean mediator of death in CD4 T-cells that replicate HIV

Sampath, R., Cummins, N. W. & Badley, A. D., Sep 27 2016, In : Journal of Cell Death. 9, p. 9-17 9 p.

Research output: Contribution to journalReview article

Is abnormal urine protein/osmolality ratio associated with abnormal renal function in patients receiving tenofovir disoproxil fumarate?

Marcelin, J. R., Berg, M. L., Tan, E. M., Amer, H., Cummins, N. W. & Rizza, S. A., Feb 2016, In : PloS one. 11, 2, e0149562.

Research output: Contribution to journalArticle

Prime, shock, and kill: Priming CD4 T cells from HIV patients with a BCL-2 antagonist before HIV reactivation reduces HIV reservoir size

Cummins, N. W., Sainski, A. M., Dai, H., Natesampillai, S., Pang, Y-P., Bren, G. D., De Araujo Correia, M. C. M., Sampath, R., Rizza, S., O'Brien, D., Yao, J. D., Kaufmann, S. H. & Badley, A. D., Apr 1 2016, In : Journal of Virology. 90, 8, p. 4032-4048 17 p.

Research output: Contribution to journalArticle

41 Scopus citations
2015

Can HIV be cured and should we try?

Cummins, N. W. & Badley, A. D., Jun 1 2015, In : Mayo Clinic Proceedings. 90, 6, p. 705-709 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Casp8p41 and HIV

Cummins, N. W. & Badley, A. D., 2015, In : Oncotarget. 6, 27, p. 23042-23043 2 p.

Research output: Contribution to journalEditorial

3 Scopus citations

Fever and cardiac arrest in a patient with a left ventricular assist device

Tan, E. M., Marcelin, J. R., Tande, A. J., Rizza, S. A. & Cummins, N. W., 2015, In : Open Forum Infectious Diseases. 2, 2, ofv033.

Research output: Contribution to journalArticle

Investigation of Efavirenz Discontinuation in Multi-ethnic Populations of HIV-positive Individuals by Genetic Analysis

Cummins, N. W., Neuhaus, J., Chu, H., Neaton, J., Wyen, C., Rockstroh, J. K., Skiest, D. J., Boyd, M. A., Khoo, S., Rotger, M., Telenti, A., Weinshilboum, R. M. & Badley, A. D., Jul 1 2015, In : EBioMedicine. 2, 7, p. 706-712 7 p.

Research output: Contribution to journalArticle

14 Scopus citations
2014

Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation

Sainski, A. M., Dai, H., Natesampillai, S., Pang, Y. P., Bren, G. D., Cummins, N. W., Correia, C., Meng, X. W., Tarara, J. E., Ramirez-Alvarado, M., Katzmann, D. J., Ochsenbauer, C., Kappes, J. C., Kaufmann, S. H. & Badley, A. D., 2014, In : Journal of Cell Biology. 206, 7, p. 867-876 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Correction to Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation [Journal of Cell Biology, 206, 7, (2014), 867-876]

Sainski, A. M., Dai, H., Natesampillai, S., Pang, Y. P., Bren, G. D., Cummins, N. W., Correia, C., Wei Meng, X., Tarara, J. E., Ramirez-Alvarado, M., Katzmann, D. J., Ochsenbauer, C., Kappes, J. C., Kaufmann, S. H. & Badley, A. D., Jan 1 2014, In : Journal of Cell Biology. 207, 1, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Mucormycosis in patients with inflammatory bowel disease: Case series and review of the literature

Abidi, M. Z., Coelho-Prabhu, N., Hargreaves, J., Weiland, T., Van Dyken, I., Tande, A., Tosh, P. K., Walker, R. C. & Cummins, N. W., 2014, In : Case Reports in Medicine. 2014, 637492.

Research output: Contribution to journalReview article

4 Scopus citations

Short communication: CD4 T cell declines occurring during suppressive antiretroviral therapy reflect continued production of Casp8p41

Cummins, N. W., Neuhaus, J., Sainski, A. M., Strausbauch, M. A., Wettstein, P. J., Lewin, S. R., Plana, M., Rizza, S. A., Temesgen, Z., Touloumi, G., Freiberg, M., Neaton, J. & Badley, A. D., May 30 2014, In : AIDS Research and Human Retroviruses. 30, 5, p. 476-479 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Stability in the cumulative incidence, severity and mortality of 101 cases of invasive mucormycosis in high-risk patients from 1995 to 2011: A comparison of eras immediately before and after the availability of voriconazole and echinocandin-amphotericin combination therapies

Abidi, M. Z., Sohail, M. R., Cummins, N., Wilhelm, M., Wengenack, N., Brumble, L., Shah, H., Jane Hata, D., Mccullough, A., Wendel, A., Vikram, H. R., Kusne, S., Litzow, M., Letendre, L., Lahr, B. D., Poeschla, E. M. & Walker, R. C., Nov 1 2014, In : Mycoses. 57, 11, p. 687-698 12 p.

Research output: Contribution to journalArticle

31 Scopus citations
2013

Anti-apoptotic mechanisms of HIV: Lessons and novel approaches to curing HIV

Cummins, N. W. & Badley, A. D., Sep 1 2013, In : Cellular and Molecular Life Sciences. 70, 18, p. 3355-3363 9 p.

Research output: Contribution to journalReview article

13 Scopus citations

Cytomegalovirus, BK, and other viral infections of the kidney

Cummins, N. W. & Sohail, M. R., Jul 1 2013, Core Concepts in Parenchymal Kidney Disease. Springer New York, p. 229-240 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

HIV replication alters the composition of extrinsic pathway coagulation factors and increases thrombin generation.

Baker, J. V., Brummel-Ziedins, K., Neuhaus, J., Duprez, D., Cummins, N., Dalmau, D., DeHovitz, J., Lehmann, C., Sullivan, A., Woolley, I., Kuller, L., Neaton, J. D., Tracy, R. P. & INSIGHT SMART Study Team, SMART. S. T., Aug 2013, In : Journal of the American Heart Association. 2, 4, p. e000264

Research output: Contribution to journalArticle

Open Access
34 Scopus citations

The Association between Serum Biomarkers and Disease Outcome in Influenza A(H1N1)pdm09 Virus Infection: Results of Two International Observational Cohort Studies

Davey, R. T., Lynfield, R., Dwyer, D. E., Losso, M. H., Cozzi-Lepri, A., Wentworth, D., Lane, H. C., Dewar, R., Rupert, A., Metcalf, J. A., Pett, S. L., Uyeki, T. M., Bruguera, J. M., Angus, B., Cummins, N., Lundgren, J. & Neaton, J. D., Feb 27 2013, In : PloS one. 8, 2, e57121.

Research output: Contribution to journalArticle

24 Scopus citations
2012

Heme oxygenase-1 regulates the immune response to influenza virus infection and vaccination in aged mice

Cummins, N. W., Weaver, E. A., May, S. M., Croatt, A. J., Foreman, O., Kennedy, R. B., Poland, G. A., Barry, M. A., Nath, K. A. & Badley, A. D., Jul 2012, In : FASEB Journal. 26, 7, p. 2911-2918 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Multiple pyogenic liver abscesses caused by Eggerthella lenta treated with ertapenem: A case report

Elias, R. M., Khoo, S. Y., Pupaibool, J., Nienaber, J. H. & Cummins, N. W., 2012, In : Case Reports in Medicine. 2012, 718130.

Research output: Contribution to journalArticle

3 Scopus citations
2011

Human immunodeficiency virus envelope protein Gp120 induces proliferation but not apoptosis in osteoblasts at physiologic concentrations

Cummins, N. W., Klicpera, A., Sainski, A. M., Bren, G. D., Khosla, S., Westendorf, J. J. & Badley, A. D., Sep 12 2011, In : PloS one. 6, 9, e24876.

Research output: Contribution to journalArticle

6 Scopus citations

Isolation of a TRAIL antagonist from the serum of HIV-infected patients

Schnepple, D. J., Shepard, B., Bren, G. D., Cummins, N. W., Natesampillai, S., Trushin, S., Algeciras-Schimnich, A., Meng, X. W., Sainski, A. M., Rizza, S. A., Kaufmann, S. H. & Badley, A. D., Oct 14 2011, In : Journal of Biological Chemistry. 286, 41, p. 35742-35754 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

The HIV-1-specific protein Casp8p41 induces death of infected cells through Bax/Bak

Sainski, A. M., Natesampillai, S., Cummins, N. W., Bren, G. D., Taylor, J., Saenz, D. T., Poeschla, E. M. & Badley, A. D., Aug 2011, In : Journal of virology. 85, 16, p. 7965-7975 11 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations
2010

Casp8p41 expression in primary T cells induces a proinflammatory response

Taylor, J. A., Cummins, N. W., Bren, G. D., Rizza, S. A., Kolbert, C. P., Behrens, M. D., Knutson, K. L., Kahl, J. C., Asmann, Y. W. & Badley, A. D., Jun 1 2010, In : AIDS. 24, 9, p. 1251-1258 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

How much Gp120 is there?

Cummins, N. W., Rizza, S. A. & Badley, A. D., Apr 15 2010, In : Journal of Infectious Diseases. 201, 8, p. 1273-1274 2 p.

Research output: Contribution to journalLetter

17 Scopus citations

Intracellular Casp8p41 content is inversely associated with CD4 T cell count

Cummins, N. W., Jiang, W., McGinty, J., Bren, G. D., Bosch, R. J., Landay, A., Deeks, S. G., Martin, J. N., Douek, D., Lederman, M. M., Brenchley, J. & Badley, A. D., Aug 1 2010, In : Journal of Infectious Diseases. 202, 3, p. 386-391 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Mechanisms of HIV-associated lymphocyte apoptosis: 2010

Cummins, N. W. & Badley, A. D., Nov 1 2010, In : Cell Death and Disease. 1, 11, e99.

Research output: Contribution to journalReview article

124 Scopus citations

Patients with discordant responses to antiretroviral therapy have impaired killing of HIV-infected T cells

Natesampillai, S., Nie, Z., Cummins, N. W., Jochmans, D., Bren, G. D., Angel, J. B. & Badley, A. D., Nov 2010, In : PLoS pathogens. 6, 11, e1001213.

Research output: Contribution to journalArticle

12 Scopus citations
5 Scopus citations
2009
45 Scopus citations

The TRAIL to viral pathogenesis: The good, the bad and the ugly

Cummins, N. & Badley, A., Aug 14 2009, In : Current Molecular Medicine. 9, 4, p. 495-505 11 p.

Research output: Contribution to journalReview article

30 Scopus citations