Nathan P Staff, MD, PhD

  • 2091 Citations
  • 23 Scopus h-Index
19962020

Research output per year

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Research Output

2020

Addressing heterogeneity in amyotrophic lateral sclerosis CLINICAL TRIALS

Goyal, N. A., Berry, J. D., Windebank, A., Staff, N. P., Maragakis, N. J., van den Berg, L. H., Genge, A., Miller, R., Baloh, R. H., Kern, R., Gothelf, Y., Lebovits, C. & Cudkowicz, M., Aug 1 2020, In : Muscle and Nerve. 62, 2, p. 156-166 11 p.

Research output: Contribution to journalReview article

Open Access

Cisplatin-associated neuropathy characteristics compared with those associated with other neurotoxic chemotherapy agents (Alliance A151724)

Albany, C., Dockter, T., Wolfe, E., Le-Rademacher, J., Wagner-Johnston, N., Einhorn, L., Lafky, J. M., Smith, E., Pachman, D., Staff, N., Ma, C., Loprinzi, C. L. & Costello, B. A., 2020, (Accepted/In press) In : Supportive Care in Cancer.

Research output: Contribution to journalArticle

Modeling chemotherapy induced peripheral neuropathy (CIPN) in vitro: Prospects and limitations

Lehmann, H. C., Staff, N. P. & Hoke, A., Apr 2020, In : Experimental Neurology. 326, 113140.

Research output: Contribution to journalReview article

Neuronal Protection for Chemotherapy Neuropathy Prevention?

Loprinzi, C. L., Hershman, D. L. & Staff, N., Jan 1 2020, In : Journal of the National Cancer Institute. 112, 1, p. 3-4 2 p.

Research output: Contribution to journalEditorial

Open Access

Pathogenesis of paclitaxel-induced peripheral neuropathy: A current review of in vitro and in vivo findings using rodent and human model systems

Staff, N. P., Fehrenbacher, J. C., Caillaud, M., Damaj, M. I., Segal, R. A. & Rieger, S., Feb 2020, In : Experimental Neurology. 324, 113121.

Research output: Contribution to journalReview article

11 Scopus citations

Postsurgical Neuropathy: A Descriptive Review

Laughlin, R. S., Johnson, R. L., Burkle, C. M. & Staff, N. P., Feb 2020, In : Mayo Clinic proceedings. 95, 2, p. 355-369 15 p.

Research output: Contribution to journalReview article

2019

Association between ALS and retroviruses: Evidence from bioinformatics analysis

Klein, J. P., Sun, Z. & Staff, N. P., Dec 20 2019, In : BMC bioinformatics. 20, 680.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Biological predictors of chemotherapy-induced peripheral neuropathy (CIPN): MASCC neurological complications working group overview

Chan, A., Hertz, D. L., Morales, M., Adams, E. J., Gordon, S., Tan, C. J., Staff, N. P., Kamath, J., Oh, J., Shinde, S., Pon, D., Dixit, N., D’Olimpio, J., Dumitrescu, C., Gobbo, M., Kober, K., Mayo, S., Pang, L., Subbiah, I., Beutler, A. S. & 3 others, Peters, K. B., Loprinzi, C. & Lustberg, M. B., Oct 1 2019, In : Supportive Care in Cancer. 27, 10, p. 3729-3737 9 p.

Research output: Contribution to journalReview article

5 Scopus citations

Case-Based Learning in Translational Biomedical Research Education: Providing Realistic and Adaptive Skills for Early-Career Scientists

Greenberg-Worisek, A. J., Campbell, K. A., Klee, E. W., Staff, N. P., Schimmenti, L. A., Weavers, K. M., Ekker, S. C. & Windebank, A. J., Feb 1 2019, In : Academic Medicine. 94, 2, p. 213-216 4 p.

Research output: Contribution to journalArticle

Chemotherapy-induced peripheral neurotoxicity: A multifaceted, still unsolved issue

on behalf of the Toxic Neuropathy Consortium of the Peripheral Nerve Society, Oct 1 2019, In : Journal of the Peripheral Nervous System. 24, S2, p. S6-S12

Research output: Contribution to journalReview article

5 Scopus citations

Clinical spectrum of neuropathy after primary total knee arthroplasty: A series of 54 cases

Speelziek, S. J. A., Staff, N. P., Johnson, R. L., Sierra, R. & Laughlin, R. S., Jun 2019, In : Muscle and Nerve. 59, 6, p. 679-682 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

DNA methylation patterns in human iPSC-derived sensory neuronal differentiation

Ankam, S., Rovini, A., Baheti, S., Hrstka, R., Wu, Y., Schmidt, K., Wang, H., Madigan, N., Koenig, L. S., Stelzig, K., Resch, Z., Klein, C. J., Sun, Z. & Staff, N. P., Sep 2 2019, In : Epigenetics. 14, 9, p. 927-937 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Dominant collagen XII mutations cause a distal myopathy

Mohassel, P., Liewluck, T., Hu, Y., Ezzo, D., Ogata, T., Saade, D., Neuhaus, S., Bolduc, V., Zou, Y., Donkervoort, S., Medne, L., Sumner, C. J., Dyck, P. J. B., Wierenga, K. J., Tennekoon, G., Finkel, R. S., Chen, J., Winder, T. L., Staff, N. P., Foley, A. R. & 2 others, Koch, M. & Bönnemann, C. G., Oct 1 2019, In : Annals of Clinical and Translational Neurology. 6, 10, p. 1980-1988 9 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Mesenchymal Stromal Cell Therapies for Neurodegenerative Diseases

Staff, N. P., Jones, D. T. & Singer, W., May 2019, In : Mayo Clinic proceedings. 94, 5, p. 892-905 14 p.

Research output: Contribution to journalReview article

Open Access
10 Scopus citations

NurOwn, phase 2, randomized, clinical trial in patients with ALS: Safety, clinical, and biomarker results

Berry, J. D., Cudkowicz, M. E., Windebank, A. J., Staff, N. P., Owegi, M., Nicholson, K., McKenna-Yasek, D., Levy, Y. S., Abramov, N., Kaspi, H., Mehra, M., Aricha, R., Gothelf, Y. & Brown, R. H., Dec 10 2019, In : Neurology. 93, 24, p. E2294-E2305

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

On the Association between Fluoroquinolones and Neuropathy

Staff, N. P. & Dyck, P. J. B., Jan 1 2019, In : JAMA neurology.

Research output: Contribution to journalEditorial

2 Scopus citations

Platinum-induced peripheral neurotoxicity: From pathogenesis to treatment

Staff, N. P., Cavaletti, G., Islam, B., Lustberg, M., Psimaras, D. & Tamburin, S., Oct 1 2019, In : Journal of the Peripheral Nervous System. 24, S2, p. S26-S39

Research output: Contribution to journalReview article

7 Scopus citations

Vinca alkaloids, thalidomide and eribulin-induced peripheral neurotoxicity: From pathogenesis to treatment

Islam, B., Lustberg, M., Staff, N. P., Kolb, N., Alberti, P. & Argyriou, A. A., Oct 1 2019, In : Journal of the Peripheral Nervous System. 24, S2, p. S63-S73

Research output: Contribution to journalReview article

3 Scopus citations
2018

Amyotrophic Lateral Sclerosis: An Update for 2018

Oskarsson, B., Gendron, T. D. & Staff, N. P., Jan 1 2018, (Accepted/In press) In : Mayo Clinic Proceedings.

Research output: Contribution to journalArticle

45 Scopus citations

A treatable hypertrophic neuropathy

Pinto, M. V., Spinner, R. & Staff, N. P., Jan 1 2018, (Accepted/In press) In : Practical Neurology.

Research output: Contribution to journalArticle

22 Scopus citations

Somatotopic heat pain thresholds and intraepidermal nerve fibers in health

Davies, J. L., Engelstad, J. K., E. Gove, L., Linbo, L. K., Carter, R. E., Lynch, C., Staff, N. P., Klein, C. J., Dyck, P. J. B., Herrmann, D. N. & Dyck, P. J., Oct 1 2018, In : Muscle and Nerve. 58, 4, p. 509-516 8 p.

Research output: Contribution to journalArticle

3 Scopus citations
2017

A pilot study of minocycline for the prevention of paclitaxel-associated neuropathy: ACCRU study RU221408I

Pachman, D. R., Dockter, T., Zekan, P. J., Fruth, B., Ruddy, K. J., Ta, L. E., Lafky, J. M., Dentchev, T., Le-Lindqwister, N. A., Sikov, W. M., Staff, N., Beutler, A. S. & Loprinzi, C. L., May 27 2017, (Accepted/In press) In : Supportive Care in Cancer. p. 1-10 10 p.

Research output: Contribution to journalArticle

20 Scopus citations
36 Scopus citations

Chemotherapy-induced peripheral neuropathy: A current review

Staff, N. P., Grisold, A., Grisold, W. & Windebank, A. J., Jun 1 2017, In : Annals of Neurology. 81, 6, p. 772-781 10 p.

Research output: Contribution to journalReview article

102 Scopus citations

Comprehensive immune profiling reveals substantial immune system alterations in a subset of patients with amyotrophic lateral sclerosis

Gustafson, M. P., Staff, N. P., Bornschlegl, S., Butler, G. W., Maas, M. L., Kazamel, M., Zubair, A., Gastineau, D. A., Windebank, A. J. & Dietz, A. B., Jul 2017, In : PloS one. 12, 7, e0182002.

Research output: Contribution to journalArticle

15 Scopus citations

Fit for chemo: Nerves may thank you

Leon-Ferre, R., Ruddy, K. J., Staff, N. P. & Loprinzi, C. L., 2017, In : Journal of the National Cancer Institute. 109, 2

Research output: Contribution to journalEditorial

1 Scopus citations

Genome editing technologies and their potential to treat neurologic disease

Madigan, N. N., Staff, N. P., Windebank, A. J. & Benarroch, E. E., Oct 17 2017, In : Neurology. 89, 16, p. 1739-1748 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Neurological Complications Associated With Anti-Programmed Death 1 (PD-1) Antibodies

Kao, J. C., Liao, B., Markovic, S. N., Klein, C. J., Naddaf, E., Staff, N. P., Liewluck, T., Hammack, J. E., Sandroni, P., Finnes, H. & Mauermann, M. M., Oct 1 2017, In : JAMA Neurology. 74, 10, p. 1216-1222 7 p.

Research output: Contribution to journalArticle

104 Scopus citations
2016

Adult-onset respiratory insufficiency, scoliosis, and distal joint hyperlaxity in patients with multiminicore disease due to novel Megf10 mutations

Liewluck, T., Milone, M., Tian, X., Engel, A. G., Staff, N. P. & Wong, L. J., Jun 1 2016, In : Muscle and Nerve. 53, 6, p. 984-988 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Comparison of oxaliplatin and paclitaxel-induced neuropathy (Alliance A151505)

Pachman, D. R., Qin, R., Seisler, D., Smith, E. M. L., Kaggal, S., Novotny, P., Ruddy, K. J., Lafky, J. M., Ta, L. E., Beutler, A. S., Wagner-Johnston, N. D., Staff, N. P., Grothey, A. F., Dougherty, P. M., Cavaletti, G. & Loprinzi, C. L., Aug 18 2016, (Accepted/In press) In : Supportive Care in Cancer. p. 1-10 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Neurotoxicity to DRG neurons varies between rodent strains treated with cisplatin and bortezomib

Podratz, J. L., Kulkarni, A., Pleticha, J., Kanwar, R., Beutler, A. S., Staff, N. P. & Windebank, A. J., Mar 15 2016, In : Journal of the Neurological Sciences. 362, p. 131-135 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Safety of intrathecal autologous adipose-derived mesenchymal stromal cells in patients with ALS

Staff, N. P., Madigan, N. N., Morris, J., Jentoft, M., Sorenson, E. J., Butler, G., Gastineau, D., Dietz, A. B. & Windebank, A. J., Nov 22 2016, In : Neurology. 87, 21, p. 2230-2234 5 p.

Research output: Contribution to journalArticle

45 Scopus citations

The immune system continues to knock at the ALS door

Staff, N. P. & Appel, S. H., Jun 1 2016, In : Neuromuscular Disorders. 26, 6, p. 335-336 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

Variability in amyotrophic lateral sclerosis

Staff, N. P., Jul 1 2016, In : JAMA Neurology. 73, 7, p. 781-782 2 p.

Research output: Contribution to journalEditorial

2015

A safety study on intrathecal delivery of autologous mesenchymal stromal cells in rabbits directly supporting Phase I human trials

Chen, B. K., Staff, N. P., Knight, A. M., Nesbitt, J. J., Butler, G. W., Padley, D. J., Parisi, J. E., Dietz, A. B. & Windebank, A. J., May 1 2015, In : Transfusion. 55, 5, p. 1013-1020 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Autonomic system and amyotrophic lateral sclerosis

Piccione, E. A., Sletten, D. M., Staff, N. P. & Low, P. A., May 1 2015, In : Muscle and Nerve. 51, 5, p. 676-679 4 p.

Research output: Contribution to journalArticle

28 Scopus citations

Candidate pathway-based genetic association study of platinum and platinum-taxane related toxicity in a cohort of primary lung cancer patients

Johnson, C., Pankratz, V. S., Velazquez, A. I., Aakre, J. A., Loprinzi, C. L., Staff, N. P., Windebank, A. J. & Yang, P., Feb 15 2015, In : Journal of the neurological sciences. 349, 1-2, p. 124-128 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

Clinical course of oxaliplatin-induced neuropathy: Results from the randomized phase III trial N08CB (Alliance)

Pachman, D. R., Qin, R., Seisler, D. K., Smith, E. M. L., Beutler, A. S., Ta, L. E., Lafky, J. M., Wagner-Johnston, N. D., Ruddy, K. J., Dakhil, S., Staff, N. P., Grothey, A. & Loprinzi, C. L., Oct 20 2015, In : Journal of Clinical Oncology. 33, 30, p. 3416-3422 7 p.

Research output: Contribution to journalArticle

96 Scopus citations

Impairments and comorbidities of polyneuropathy revealed by population-based analyses

Hoffman, E. M., Staff, N. P., Robb, J. M., St. Sauver, J., Dyck, P. J. & Klein, C. J., Apr 21 2015, In : Neurology. 84, 16, p. 1644-1651 8 p.

Research output: Contribution to journalArticle

38 Scopus citations
21 Scopus citations

Neuropathies after surgery: Anatomical considerations of pathologic mechanisms

Johnson, R. L., Warner, M. E., Staff, N. P. & Warner, M. A., Jul 1 2015, In : Clinical Anatomy. 28, 5, p. 678-682 5 p.

Research output: Contribution to journalArticle

9 Scopus citations
2014

Breaking down translation barriers: Investigator's perspective

Staff, N. P., Runge, B. K. & Windebank, A. J., Sep 3 2014, In : Science translational medicine. 6, 252, 252cm7.

Research output: Contribution to journalComment/debate

7 Scopus citations

Chronic meralgia paresthetica and neurectomy: A clinical pathologic study

Berini, S. E., Spinner, R. J., Jentoft, M. E., Engelstad, J. N. K., Staff, N. P., Suanprasert, N., Dyck, P. J. B. & Klein, C. J., Apr 29 2014, In : Neurology. 82, 17, p. 1551-1555 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Ipsilateral inflammatory neuropathy after hip surgery

Laughlin, R. S., Dyck, P. J. B., Watson, J. C., Spinner, R. J., Amrami, K. K., Sierra, R. J., Trousdale, R. T. & Staff, N. P., Apr 2014, In : Mayo Clinic proceedings. 89, 4, p. 454-461 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Peripheral neuropathy due to vitamin deficiency, toxins, and medications

Staff, N. P. & Windebank, A. J., Oct 1 2014, In : Continuum (Minneapolis, Minn.). 20, 5 Peripheral Nervous System Disorders, p. 1293-1306 14 p.

Research output: Contribution to journalArticle

24 Scopus citations
2 Scopus citations
2013

An automated climbing apparatus to measure chemotherapy-induced neurotoxicity in Drosophila melanogaster

Podratz, J. L., Staff, N. P., Boesche, J. B., Giorno, N. J., Hainy, M. E., Herring, S. A., Klennert, M. T., Milaster, C., Nowakowski, S. E., Krug, R. G., Peng, Y. & Windebank, A. J., Jan 1 2013, In : Fly. 7, 3

Research output: Contribution to journalArticle

12 Scopus citations

Assessing decreased sensation and increased sensory phenomena in diabetic polyneuropathies

Dyck, P. J., Herrmann, D. N., Staff, N. P. & Dyck, P. J. B., Nov 1 2013, In : Diabetes. 62, 11, p. 3677-3686 10 p.

Research output: Contribution to journalReview article

33 Scopus citations

Bortezomib alters microtubule polymerization and axonal transport in rat dorsal root ganglion neurons

Staff, N. P., Podratz, J. L., Grassner, L., Bader, M., Paz, J., Knight, A. M., Loprinzi, C. L., Trushina, E. & Windebank, A. J., Dec 1 2013, In : NeuroToxicology. 39, p. 124-131 8 p.

Research output: Contribution to journalArticle

45 Scopus citations