Nadia N Laack, MD

  • 2737 Citations
  • 28 Scopus h-Index
19962019

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2019

Anaplastic Ependymoma and Posterior Fossa Grouping in a Patient With H3K27ME3 Loss of Expression but Chromosomal Imbalance

Routman, D. M., Raghunathan, A., Giannini, C., Mahajan, A., Beltran, C., Nagib, M. G., Nageswara Rao, A. A., Skrypek, M. M. & Laack, N. N., Jan 1 2019, In : Advances in Radiation Oncology.

Research output: Contribution to journalArticle

Open Access

Biologic Dose and Imaging Changes in Pediatric Brain Tumor Patients Receiving Spot Scanning Proton Therapy

Roberts, K. W., Wan Chan Tseung, H. S., Eckel, L. J., Harmsen, W. S., Beltran, C. & Laack, N. N., Jan 1 2019, (Accepted/In press) In : International Journal of Radiation Oncology Biology Physics.

Research output: Contribution to journalArticle

1 Scopus citations

Desmoplastic Infantile Ganglioglioma: A MAPK Pathway-Driven and Microglia/Macrophage-Rich Neuroepithelial Tumor

Blessing, M. M., Blackburn, P. R., Krishnan, C., Harrod, V. L., Barr Fritcher, E. G., Zysk, C. D., Jackson, R. A., Milosevic, D., Nair, A. A., Davila, J. I., Balcom, J. R., Jenkins, R. B., Halling, K. C., Kipp, B. R., Nageswara Rao, A. A., Laack, N. N., Daniels, D. J., Macon, W. R. & Ida, C. M., Nov 1 2019, In : Journal of Neuropathology and Experimental Neurology. 78, 11, p. 1011-1021 11 p.

Research output: Contribution to journalArticle

Patterns of proton therapy use in pediatric cancer management in 2016: An international survey

Journy, N., Indelicato, D. J., Withrow, D. R., Akimoto, T., Alapetite, C., Araya, M., Chang, A., Chang, J. H. C., Chon, B., Confer, M. E., Demizu, Y., Dendale, R., Doyen, J., Ermoian, R., Gurtner, K., Hill-Kayser, C., Iwata, H., Kim, J. Y., Kwok, Y., Laack, N. N. & 26 others, Lee, C., Lim, D. H., Loredo, L., Mangona, V. S., Mansur, D. B., Murakami, M., Murayama, S., Ogino, T., Ondrová, B., Parikh, R. R., Paulino, A. C., Perkins, S., Ramakrishna, N. R., Richter, R., Rombi, B., Shibata, S., Shimizu, S., Timmermann, B., Vern-Gross, T., Wang, C. J., Weber, D. C., Wilkinson, J. B., Witt Nyström, P., Yock, T. I., Kleinerman, R. A. & Berrington de Gonzalez, A., Mar 2019, In : Radiotherapy and Oncology. 132, p. 155-161 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Pretreatment Volume of MRI-Determined White Matter Injury Predicts Neurocognitive Decline After Hippocampal Avoidant Whole-Brain Radiation Therapy for Brain Metastases: Secondary Analysis of NRG Oncology Radiation Therapy Oncology Group 0933

Bovi, J. A., Pugh, S. L., Sabsevitz, D., Robinson, C. G., Paulson, E., Mehta, M. P., Gondi, V., Kundapur, V., Shahin, M. S., Chao, S. T., Machtay, M., DeNittis, A. S., Laack, N. N., Greenspoon, J. N., Moore, K. N., Huang, J., Dominello, M. M. & Kachnic, L. A., Jan 1 2019, (Accepted/In press) In : Advances in Radiation Oncology.

Research output: Contribution to journalArticle

Open Access

Pseudoprogression after radiation therapies for low grade glioma in children and adults: A systematic review and meta-analysis

Lu, V. M., Welby, J. P., Laack, N. N., Mahajan, A. & Daniels, D., Jan 1 2019, (Accepted/In press) In : Radiotherapy and Oncology.

Research output: Contribution to journalArticle

2 Scopus citations

Reirradiation in Pediatric Patients With Recurrent Brain Tumors: A Last Hope, But One With Greatly Feared Consequences

Ermoian, R., MacDonald, S., Laack, N. N., Baldini, E. & Breneman, J., Jan 1 2019, In : International Journal of Radiation Oncology, Biology, Physics. 103, 1, p. 1-4 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Soft tissue sarcoma stiffness and perfusion evaluation by MRE and DCE-MRI for radiation therapy response assessment: A technical feasibility study

Pepin, K., Grimm, R., Kargar, S., Howe, B. M., Fritchie, K., Frick, M., Wenger, D., Okuno, S. H., Ehman, R. L., McGee, K. P., James, S., Laack, N. N., Herman, M. & Pafundi, D., May 2 2019, In : Biomedical Physics and Engineering Express. 5, 4, 047003.

Research output: Contribution to journalArticle

The association of health-related quality of life and cognitive function in patients receiving memantine for the prevention of cognitive dysfunction during whole-brain radiotherapy

Laack, N. N., Pugh, S. L., Brown, P. D., Fox, S., Wefel, J. S., Meyers, C., Choucair, A., Khuntia, D., Suh, J. H., Roberge, D., Wendland, M. M. & Bruner, D., Jul 27 2019, In : Neuro-Oncology Practice. 6, 4, p. 274-282 9 p., npy038.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Treatment of WHO Grade 2 and 3 Gliomas With Potentially Favorable Survival: Is Monotherapy Obsolete?

Soltys, S. G., Laack, N. N., Halasz, L. M., Minniti, G., Chan, M. D. & Kirkpatrick, J. P., Mar 1 2019, In : International journal of radiation oncology, biology, physics. 103, 3, p. 533-536 4 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

An update from the Pediatric Proton Consortium Registry

Hess, C. B., Indelicato, D. J., Paulino, A. C., Hartsell, W. F., Hill-Kayser, C. E., Perkins, S. M., Mahajan, A., Laack, N. N., Ermoian, R. P., Chang, A. L., Wolden, S. L., Mangona, V. S., Kwok, Y., Breneman, J. C., Perentesis, J. P., Gallotto, S. L., Weyman, E. A., Bajaj, B. V. M., Lawell, M. P., Yeap, B. Y. & 1 others, Yock, T. I., May 24 2018, In : Frontiers in Oncology. 8, MAY, 165.

Research output: Contribution to journalArticle

12 Scopus citations

Association of MGMT Promoter Methylation Status with Survival Outcomes in Patients with High-Risk Glioma Treated with Radiotherapy and Temozolomide: An Analysis from the NRG Oncology/RTOG 0424 Trial

Bell, E. H., Zhang, P., Fisher, B. J., Macdonald, D. R., McElroy, J. P., Lesser, G. J., Fleming, J., Chakraborty, A. R., Liu, Z., Becker, A. P., Fabian, D., Aldape, K. D., Ashby, L. S., Werner-Wasik, M., Walker, E. M., Bahary, J. P., Kwok, Y., Yu, H. M., Laack, N. N., Schultz, C. J. & 4 others, Gray, H. J., Robins, H. I., Mehta, M. P. & Chakravarti, A., Oct 2018, In : JAMA Oncology. 4, 10, p. 1405-1409 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

Data collection of patient outcomes: One institution's experience

Whitaker, T. J., Mayo, C. S., Ma, D. J., Haddock, M. G., Miller, R. C., Corbin, K. S., Neben-Wittich, M., Leenstra, J. L., Laack, N. N., Fatyga, M., Schild, S. E., Vargas, C. E., Tzou, K. S., Hadley, A. R., Buskirk, S. J. & Foote, R. L., Mar 1 2018, In : Journal of Radiation Research. 59, p. i19-i24

Research output: Contribution to journalArticle

Open Access

External beam radiation therapy for advanced/unresectable malignant paraganglioma and pheochromocytoma

Breen, W., Bancos, I., Young, W. F., Bible, K. C., Laack, N. N., Foote, R. L. & Hallemeier, C., Jan 1 2018, (Accepted/In press) In : Advances in Radiation Oncology.

Research output: Contribution to journalArticle

9 Scopus citations

Is the blood-brain barrier really disrupted in all glioblastomas? A critical assessment of existing clinical data

Sarkaria, J. N., Hu, L. S., Parney, I. F., Pafundi, D. H., Brinkmann, D. H., Laack, N. N., Giannini, C., Burns, T. C., Kizilbash, S. H., Laramy, J. K., Swanson, K. R., Kaufmann, T. J., Brown, P. D., Agar, N. Y. R., Galanis, E., Buckner, J. C. & Elmquist, W. F., Jan 22 2018, In : Neuro-oncology. 20, 2, p. 184-191 8 p.

Research output: Contribution to journalArticle

72 Scopus citations

Modern reirradiation for recurrent gliomas can safely delay tumor progression

Youland, R. S., Lee, J. Y., Kreofsky, C. R., Brown, P. D., Uhm, J. H. & Laack, N. N., Mar 2 2018, In : Neuro-Oncology Practice. 5, 1, p. 46-55 10 p.

Research output: Contribution to journalArticle

Necessity of multimodal treatment of acromegaly and outcomes

Donegan, D. M., Iñiguez-Ariza, N., Sharma, A., Nippoldt, T., Young, W. F., Van Gompel, J., Atkinson, J., Meyer, F., Pollock, B., Natt, N., Laack, N. N. & Erickson, D., Jul 1 2018, In : Endocrine Practice. 24, 7, p. 668-676 9 p.

Research output: Contribution to journalArticle

Preoperative stereotactic radiosurgery for brain metastases

Routman, D. M., Yan, E., Vora, S., Peterson, J., Mahajan, A., Chaichana, K. L., Laack, N. N., Brown, P. D., Parney, I. F., Burns, T. & Trifiletti, D., Nov 13 2018, In : Frontiers in Neurology. 9, NOV, 201800959.

Research output: Contribution to journalArticle

3 Scopus citations

Prospective trial evaluating the sensitivity and specificity of 3,4-dihydroxy-6-[18F]-fluoro-l-phenylalanine (18F-DOPA) PET and MRI in patients with recurrent gliomas

Youland, R. S., Pafundi, D. H., Brinkmann, D. H., Lowe, V. J., Morris, J. M., Kemp, B. J., Hunt, C. H., Giannini, C., Parney, I. F. & Laack, N. N., May 1 2018, In : Journal of neuro-oncology. 137, 3, p. 583-591 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Proton therapy for pediatric malignancies: Fact, figures and costs. A joint consensus statement from the pediatric subcommittee of PTCOG, PROS and EPTN

Weber, D. C., Habrand, J. L., Hoppe, B. S., Hill Kayser, C., Laack, N. N., Langendijk, J. A., MacDonald, S. M., McGovern, S. L., Pater, L., Perentesis, J. P., Thariat, J., Timmerman, B., Yock, T. I. & Mahajan, A., Jan 1 2018, (Accepted/In press) In : Radiotherapy and Oncology.

Research output: Contribution to journalArticle

13 Scopus citations

Provider views on the management of Ewing sarcoma of the spine and pelvis

Zhu, C., Olson, K. A., Roth, M., Geller, D. S., Gorlick, R. G., Gill, J., Laack, N. N. & Randall, R. L., Mar 1 2018, In : Journal of Surgical Oncology. 117, 3, p. 417-424 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Survivorship care planning in neuro-oncology

Leeper, H. E., Acquaye, A. A., Bell, S., Clarke, J. L., Forst, D., Laack, N. N., Link, M. J., Taylor, J. W. & Armstrong, T. S., Mar 2 2018, In : Neuro-Oncology Practice. 5, 1, p. 3-9 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
2017

Clinical efficacy and safety of a highly conformal, supine, hybrid forward and inverse planned intensity modulated radiation therapy technique for craniospinal irradiation

Ahmed, S. K., Kruse, J. J., Bradley, T. B., Beltran, C. J. & Laack, N. N., Nov 11 2017, (Accepted/In press) In : Acta Oncologica. p. 1-8 8 p.

Research output: Contribution to journalArticle

Gamma knife radiosurgery for the treatment of uveal melanoma and uveal metastases

Reynolds, M. M., Arnett, A. L., Parney, I. F., Kumar, R., Laack, N. N., Maloney, P. R., Kozelsky, T. F., Garces, Y. I., Foote, R. L. & Pulido, J. S., Jan 1 2017, In : International Journal of Retina and Vitreous. 3, 1, 17.

Research output: Contribution to journalArticle

5 Scopus citations

Gamma Knife Stereotactic Radiosurgery for the Treatment of Primary and Metastatic Ocular Malignancies

Arnett, A. L. H., Reynolds, M. M., Pulido, J. S., Parney, I. F. & Laack, N. N., Nov 4 2017, (Accepted/In press) In : Stereotactic and Functional Neurosurgery. p. 363-368 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Identification of Patients With Localized Ewing Sarcoma at Higher Risk for Local Failure: A Report From the Children's Oncology Group

Ahmed, S. K., Randall, R. L., DuBois, S. G., Harmsen, W. S., Krailo, M., Marcus, K. J., Janeway, K. A., Geller, D. S., Sorger, J. I., Womer, R. B., Granowetter, L., Grier, H. E., Gorlick, R. G. & Laack, N. N., 2017, (Accepted/In press) In : International Journal of Radiation Oncology Biology Physics.

Research output: Contribution to journalArticle

10 Scopus citations

Management of GBM: a problem of local recurrence

Kirkpatrick, J. P., Laack, N. N., Shih, H. A. & Gondi, V., Apr 4 2017, (Accepted/In press) In : Journal of Neuro-Oncology. p. 1-7 7 p.

Research output: Contribution to journalArticle

7 Scopus citations
5 Scopus citations

Patterns of care and treatment outcomes in older adults with low grade glioma: a 50-year experience

Youland, R. S., Schomas, D. A., Brown, P. D., Parney, I. F. & Laack, N. N., Apr 21 2017, (Accepted/In press) In : Journal of Neuro-Oncology. p. 1-8 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Pelvis Ewing sarcoma: Local control and survival in the modern era

Ahmed, S. K., Robinson, S., Arndt, C. A. S., Petersen, I. A., Haddock, M., Rose, P. S. & Laack, N. N., 2017, (Accepted/In press) In : Pediatric Blood and Cancer.

Research output: Contribution to journalArticle

5 Scopus citations

Photon and Proton Radiation Therapy Utilization in a Population of More Than 100 Million Commercially Insured Patients

Waddle, M. R., Sio, T. T., Van Houten, H. K., Foote, R. L., Keole, S. R., Schild, S. E., Laack, N. N., Daniels, T. B., Crown, W., Shah, N. D. & Miller, R. C., 2017, (Accepted/In press) In : International Journal of Radiation Oncology Biology Physics.

Research output: Contribution to journalArticle

8 Scopus citations

Postoperative stereotactic radiosurgery compared with whole brain radiotherapy for resected metastatic brain disease (NCCTG N107C/CEC·3): a multicentre, randomised, controlled, phase 3 trial

Brown, P. D., Ballman, K. V., Cerhan, J. H., Anderson, S. K., Carrero, X. W., Whitton, A. C., Greenspoon, J., Parney, I. F., Laack, N. N., Ashman, J. B., Bahary, J. P., Hadjipanayis, C. G., Urbanic, J. J., Barker, F. G., Farace, E., Khuntia, D., Giannini, C., Buckner, J. C., Galanis, E. & Roberge, D., Aug 1 2017, In : The Lancet Oncology. 18, 8, p. 1049-1060 12 p.

Research output: Contribution to journalArticle

233 Scopus citations

The impact of adjuvant therapy for patients with high-risk diffuse WHO grade II glioma

Youland, R. S., Kreofsky, C. R., Schomas, D. A., Brown, P. D., Buckner, J. C. & Laack, N. N., Aug 23 2017, (Accepted/In press) In : Journal of Neuro-Oncology. p. 1-9 9 p.

Research output: Contribution to journalArticle

12 Scopus citations
2016

Comparison of clinical features and outcomes in patients with extraskeletal versus skeletal localized Ewing sarcoma: A report from the Children's Oncology Group

Cash, T., McIlvaine, E., Krailo, M. D., Lessnick, S. L., Lawlor, E. R., Laack, N., Sorger, J., Marina, N., Grier, H. E., Granowetter, L., Womer, R. B. & DuBois, S. G., Oct 1 2016, In : Pediatric Blood and Cancer. 63, 10, p. 1771-1779 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Dosimetric analysis of varying cord planning organ at risk volume in spine stereotactic body radiation therapy

Owen, D., Mayo, C. S., Song, L., Ahmed, K., Laack, N. & Olivier, K., Jan 1 2016, In : Advances in Radiation Oncology. 1, 1, p. 76-81 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Gamma Knife radiosurgery for neurofibromatosis type 2-associated meningiomas: a 22-year patient series

Birckhead, B., Sio, T. T., Pollock, B. E., Link, M. J. & Laack, N. N., Dec 1 2016, In : Journal of Neuro-Oncology. 130, 3, p. 553-560 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Local Control Modality and Outcome for Ewing Sarcoma of the Femur: A Report From the Children’s Oncology Group

Daw, N. C., Laack, N. N., McIlvaine, E. J., Krailo, M., Womer, R. B., Granowetter, L., Grier, H. E., Marina, N. M., Bernstein, M. L., Gebhardt, M. C., Marcus, K. J., Advani, S. M., Healey, J. H., Letson, G. D., Gorlick, R. G. & Randall, R. L., Oct 1 2016, In : Annals of surgical oncology. 23, 11, p. 3541-3547 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Patterns of failure and optimal radiotherapy target volumes in primary intradural extramedullary Ewing sarcoma

Chihak, M. A., Ahmed, S. K., Lachance, D. H., Nageswara Rao, A. A. & Laack, N. N., Mar 7 2016, (Accepted/In press) In : Acta Oncologica. p. 1-5 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Pilot Study of Adding Vincristine, Topotecan, and Cyclophosphamide to Interval-Compressed Chemotherapy in Newly Diagnosed Patients With Localized Ewing Sarcoma: A Report From the Children's Oncology Group

Mascarenhas, L., Felgenhauer, J. L., Bond, M. C., Villaluna, D., Femino, J. D., Laack, N. N., Ranganathan, S., Meyer, J., Womer, R. B., Gorlick, R., Krailo, M. D. & Marina, N., Mar 1 2016, In : Pediatric Blood and Cancer. 63, 3, p. 493-498 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Post-WBRT cognitive impairment and hippocampal neuronal depletion measured by in vivo metabolic MR spectroscopy: Results of prospective investigational study

Pospisil, P., Kazda, T., Hynkova, L., Bulik, M., Dobiaskova, M., Burkon, P., Laack, N. N., Slampa, P. & Jancalek, R., Feb 14 2016, (Accepted/In press) In : Radiotherapy and Oncology.

Research output: Contribution to journalArticle

18 Scopus citations
2015

Double-blind, placebo-controlled pilot study of processed ultra emu oil versus placebo in the prevention of radiation dermatitis

Rollmann, D. C., Novotny, P. J., Petersen, I. A., Garces, Y. I., Bauer, H. J., Yan, E. S., Wahner-Roedler, D., Vincent, A., Sloan, J. A. & Laack, N. N., Jul 1 2015, In : International Journal of Radiation Oncology Biology Physics. 92, 3, p. 650-658 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Establishment of practice standards in nomenclature and prescription to enable construction of software and databases for knowledge-based practice review

Mayo, C. S., Pisansky, T. M., Petersen, I. A., Yan, E. S., Davis, B. J., Stafford, S. L., Garces, Y. I., Miller, R. C., Martenson, J. A., Mutter, R., Choo, R., Hallemeier, C., Laack, N. N., Park, S. S., Ma, D. J., Olivier, K. R., Keole, S. R., Fatyga, M., Foote, R. L. & Haddock, M., May 3 2015, (Accepted/In press) In : Practical Radiation Oncology.

Research output: Contribution to journalArticle

17 Scopus citations
5 Scopus citations

Health related quality of life (HRQOL) in long-term survivors of pediatric low grade gliomas (LGGs)

Nwachukwu, C. R., Youland, R. S., Chioreso, C., Wetjen, N., NageswaraRao, A., Keating, G. & Laack, N. N., Jan 1 2015, In : Journal of neuro-oncology. 121, 3, p. 599-607 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Injury to Insult: Infarction after Radiotherapy in the Treatment of Pediatric Brain Tumor

Elwood, K., Laack, N. N., Warad, D. M., Keating, G., Eckel, L. & Nageswara Rao, A. A., May 1 2015, In : Pediatric Neurology. 52, 5, p. 552-553 2 p.

Research output: Contribution to journalArticle

Is Less, More? the Evolving Role of Radiation Therapy for Brain Metastases

Soltys, S. G., Kirkpatrick, J. P., Laack, N. N., Kavanagh, B. D., Breneman, J. C. & Shih, H. A., Aug 1 2015, In : International Journal of Radiation Oncology Biology Physics. 92, 5, p. 963-966 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Outcomes following myxopapillary ependymoma resection: The importance of capsule integrity

Abdulaziz, M., Mallory, G. W., Bydon, M., Ramos, R. D. L. G., Ellis, J. A., Laack, N. N., Marsh, W. R., Krauss, W. E., Jallo, G., Gokaslan, Z. L. & Clarke, M. J., Jan 1 2015, In : Neurosurgical focus. 39, 2, p. E8

Research output: Contribution to journalArticle

18 Scopus citations

Patient-Reported Functional and Quality of Life Outcomes in a Large Cohort of Long-Term Survivors of Ewing Sarcoma

Stish, B. J., Ahmed, S. K., Rose, P. S., Arndt, C. A. S. & Laack, N. N., Dec 1 2015, In : Pediatric Blood and Cancer. 62, 12, p. 2189-2196 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Phase II trial of pre-irradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: long term results of RTOG BR0131

Vogelbaum, M. A., Hu, C., Peereboom, D. M., Macdonald, D. R., Giannini, C., Suh, J. H., Jenkins, R. B., Laack, N. N., Brachman, D. G., Shrieve, D. C., Souhami, L. & Mehta, M. P., Jun 19 2015, In : Journal of Neuro-Oncology. 124, 3, p. 413-420 8 p.

Research output: Contribution to journalArticle

9 Scopus citations