Research output

Research output per year 2007 2017 2020 2022 2023 2023

• 33 Article
• 6 Review article
• 2 Comment/debate

Research output per year

Research output per year

Search results

• 2023

  APOE2 Exacerbates TDP-43 Related Toxicity in the Absence of Alzheimer Pathology

  Meneses, A. D., Koga, S., Li, Z., O'Leary, J., Li, F., Chen, K., Murakami, A., Qiao, W., Kurti, A., Heckman, M. G., White, L., Xie, M., Chen, Y., Finch, N. A., Lim, M. J., Delenclos, M., DeTure, M. A., Linares, C., Martin, N. B., Ikezu, T. C., & 8 othersvan Blitterswijk, M. M., Wu, L. J., McLean, P. J., Rademakers, R., Ross, O. A., Dickson, D. W., Bu, G. & Zhao, N., Apr 2023, In: Annals of neurology. 93, 4, p. 830-843 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Pathology 100%
  • ApoE Knockout Mice 85%
  • Alzheimer Disease 81%
  • Frontotemporal Lobar Degeneration 74%
  • Motor Neuron Disease 66%

• A TREM2 antibody energizes microglia

  Zhao, N. & Bu, G., Mar 2023, In: Nature Neuroscience. 26, 3, p. 366-368 3 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• Correction: Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology (Molecular Neurodegeneration, (2023), 18, 1, (8), 10.1186/s13024-023-00599-3)

  Qiao, W., Chen, Y., Zhong, J., Madden, B. J., Charlesworth, C. M., Martens, Y. A., Liu, C. C., Knight, J., Ikezu, T. C., Aishe, K., Zhu, Y., Meneses, A., Rosenberg, C. L., Kuchenbecker, L. A., Vanmaele, L. K., Li, F., Chen, K., Shue, F., Dacquel, M. V., Fryer, J., & 3 othersPandey, A., Zhao, N. & Bu, G., Dec 2023, In: Molecular neurodegeneration. 18, 1, 28.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Molecular Pathology 100%
  • Amyloid 82%

• Deconvolution reveals cell-type-specific transcriptomic changes in the aging mouse brain

  Ren, Y., Wang, X., Zhang, S., Hu, H., Quicksall, Z., Lee, S., Morganti, J. M., Johnson, L. A., Asmann, Y. W. & Zhao, N., Dec 2023, In: Scientific reports. 13, 1, 16855.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gene Regulatory Networks 100%
  • Brain 75%
  • Oligodendroglia 50%
  • Microglia 46%
  • Blood Vessels 36%

• Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of Alzheimer’s disease related proteins

  for the Alzheimer's Disease Neuroimaging Initiative, Dec 2023, In: Molecular neurodegeneration. 18, 1, 2.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Genome-Wide Association Study 100%
  • Alzheimer Disease 74%
  • Phenotype 57%
  • Brain 46%
  • Proteins 35%

• Standardized immunoprecipitation protocol for efficient isolation of native apolipoprotein E particles utilizing HJ15.4 monoclonal antibody

  O'Leary, J., Raulin, A. C., Li, Z., Martens, Y., Inoue, Y., Strickland, M. R., Han, X., Holtzman, D. M., Bu, G. & Zhao, N., Jun 16 2023, In: STAR Protocols. 4, 2, 102271.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apolipoproteins E 100%
  • Immunoprecipitation 91%
  • Monoclonal Antibodies 68%
  • Protein 38%
  • Proteins 34%

• Suppression of Wnt/β-Catenin Signaling Is Associated with Downregulation of Wnt1, PORCN, and Rspo2 in Alzheimer’s Disease

  Macyczko, J. R., Wang, N., Zhao, J., Ren, Y., Lu, W., Ikezu, T. C., Zhao, N., Liu, C. C., Bu, G. & Li, Y., Jan 2023, In: Molecular Neurobiology. 60, 1, p. 26-35 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Porcupines 100%
  • Catenins 74%
  • Alzheimer Disease 45%
  • Down-Regulation 41%
  • Brain 21%

• Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology

  Qiao, W., Chen, Y., Zhong, J., Madden, B. J., Charlesworth, C. M., Martens, Y. A., Liu, C. C., Knight, J., Ikezu, T. C., Aishe, K., Zhu, Y., Meneses, A., Rosenberg, C. L., Kuchenbecker, L. A., Vanmaele, L. K., Li, F., Chen, K., Shue, F., Dacquel, M. V., Fryer, J., & 3 othersPandey, A., Zhao, N. & Bu, G., Dec 2023, In: Molecular neurodegeneration. 18, 1, 8.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Myeloid Cells 100%
  • Amyloid 92%
  • Pathology 61%
  • Alzheimer Disease 23%
  • Mutation 13%
• 2022

  APOE4 exacerbates α-synuclein seeding activity and contributes to neurotoxicity in Alzheimer’s disease with Lewy body pathology

  Jin, Y., Li, F., Sonoustoun, B., Kondru, N. C., Martens, Y. A., Qiao, W., Heckman, M. G., Ikezu, T. C., Li, Z., Burgess, J. D., Amerna, D., O’Leary, J., DeTure, M. A., Zhao, J., McLean, P. J., Dickson, D. W., Ross, O. A., Bu, G. & Zhao, N., Jun 2022, In: Acta neuropathologica. 143, 6, p. 641-662 22 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Synucleins 100%
  • Lewy Bodies 85%
  • Alzheimer Disease 51%
  • Pathology 41%
  • Autopsy 11%

• ApoE Cascade Hypothesis in the pathogenesis of Alzheimer's disease and related dementias

  Martens, Y. A., Zhao, N., Liu, C. C., Kanekiyo, T., Yang, A. J., Goate, A. M., Holtzman, D. M. & Bu, G., Apr 20 2022, In: Neuron. 110, 8, p. 1304-1317 14 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Apolipoproteins E 100%
  • Dementia 78%
  • Alzheimer Disease 73%
  • Apolipoprotein E4 64%
  • Protein Isoforms 37%

• Clinicopathologic Factors Associated With Reversion to Normal Cognition in Patients With Mild Cognitive Impairment

  Li, Z., Heckman, M. G., Kanekiyo, T., Martens, Y. A., Day, G. S., Vassilaki, M., Liu, C. C., Bennett, D. A., Petersen, R. C., Zhao, N. & Bu, G., May 17 2022, In: Neurology. 98, 20, p. E2036-E2045

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cognitive Dysfunction 100%
  • Cognition 96%
  • Memory 71%
  • Amyloid 46%
  • Glucose 46%

• Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia

  Zhao, N., Qiao, W., Li, F., Ren, Y., Zheng, J., Martens, Y. A., Wang, X., Li, L., Liu, C. C., Chen, K., Zhu, Y., Ikezu, T. C., Li, Z., Meneses, A. D., Jin, Y., Knight, J. A., Chen, Y., Bastea, L., Linares, C., Sonustun, B., & 11 othersJob, L., Smith, M. L., Xie, M., Liu, Y. U., Umpierre, A. D., Haruwaka, K., Quicksall, Z. S., Storz, P., Asmann, Y. W., Wu, L. J. & Bu, G., Dec 5 2022, In: Journal of Experimental Medicine. 219, 12, e20212479.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Microglia 100%
  • Amyloid 93%
  • Alzheimer Disease 76%
  • RNA Sequence Analysis 22%
  • Antigen Presentation 21%

• LRP1 is a neuronal receptor for α-synuclein uptake and spread

  Chen, K., Martens, Y. A., Meneses, A., Ryu, D. H., Lu, W., Raulin, A. C., Li, F., Zhao, J., Chen, Y., Jin, Y., Linares, C., Goodwin, M., Li, Y., Liu, C. C., Kanekiyo, T., Holtzman, D. M., Golde, T. E., Bu, G. & Zhao, N., Dec 2022, In: Molecular neurodegeneration. 17, 1, 57.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Synucleins 100%
  • Lipoprotein Receptors 94%
  • Proteins 24%
  • Neurons 18%
  • Lysine 14%

• Network approaches for omics studies of neurodegenerative diseases

  Zhao, N., Quicksall, Z., Asmann, Y. W. & Ren, Y., Sep 16 2022, In: Frontiers in Genetics. 13, 984338.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Neurodegenerative Diseases 100%
  • Lipidomics 78%
  • Big Data 78%
  • Metabolomics 63%
  • Brain Diseases 54%

• Peripheral apoE4 enhances Alzheimer’s pathology and impairs cognition by compromising cerebrovascular function

  Liu, C. C., Zhao, J., Fu, Y., Inoue, Y., Ren, Y., Chen, Y., Doss, S. V., Shue, F., Jeevaratnam, S., Bastea, L., Wang, N., Martens, Y. A., Qiao, W., Wang, M., Zhao, N., Jia, L., Yamazaki, Y., Yamazaki, A., Rosenberg, C. L., Wang, Z., & 20 othersKong, D., Li, Z., Kuchenbecker, L. A., Trottier, Z. A., Felton, L., Rogers, J., Quicksall, Z. S., Linares, C., Knight, J., Chen, Y., Kurti, A., Kanekiyo, T., Fryer, J. D., Asmann, Y. W., Storz, P., Wang, X., Peng, J., Zhang, B., Kim, B. Y. S. & Bu, G., Aug 2022, In: Nature Neuroscience. 25, 8, p. 1020-1033 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apolipoprotein E4 100%
  • Apolipoproteins E 78%
  • Cognition 58%
  • Pathology 46%
  • Apolipoprotein E3 36%

• TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration

  Xie, M., Liu, Y. U., Zhao, S., Zhang, L., Bosco, D. B., Pang, Y. P., Zhong, J., Sheth, U., Martens, Y. A., Zhao, N., Liu, C. C., Zhuang, Y., Wang, L., Dickson, D. W., Mattson, M. P., Bu, G. & Wu, L. J., Jan 2022, In: Nature Neuroscience. 25, 1, p. 26-38 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • DNA-Binding Proteins 100%
  • Neuroprotection 93%
  • Myeloid Cells 91%
  • Microglia 33%
  • human TDP-43 protein 22%
• 2021

  APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia

  Liu, C. C., Murray, M. E., Li, X., Zhao, N., Wang, N., Heckman, M. G., Shue, F., Martens, Y., Li, Y., Raulin, A. C., Rosenberg, C. L., Doss, S. V., Zhao, J., Wren, M. C., Jia, L., Ren, Y., Ikezu, T. C., Lu, W., Fu, Y., Caulfield, T., & 27 othersTrottier, Z. A., Knight, J., Chen, Y., Linares, C., Wang, X., Kurti, A., Asmann, Y. W., Wszolek, Z. K., Smith, G. E., Vemuri, P., Kantarci, K., Knopman, D. S., Lowe, V. J., Jack, C. R., Parisi, J. E., Ferman, T. J., Boeve, B. F., Graff-Radford, N. R., Petersen, R. C., Younkin, S. G., Fryer, J. D., Wang, H., Han, X., Frieden, C., Dickson, D. W., Ross, O. A. & Bu, G., Sep 29 2021, In: Science translational medicine. 13, 613, eabc9375.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dementia 100%
  • Alzheimer Disease 92%
  • Lewy Bodies 66%
  • Apolipoproteins E 54%
  • Brain 25%

• A water pill against Alzheimer’s disease

  Li, Z. & Zhao, N., Oct 2021, In: Nature Aging. 1, 10, p. 868-869 2 p.

  Research output: Contribution to journal › Article › peer-review

• TDP-43 Pathology in Alzheimer’s Disease

  Meneses, A., Koga, S., O’Leary, J., Dickson, D. W., Bu, G. & Zhao, N., Dec 2021, In: Molecular neurodegeneration. 16, 1, 84.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Alzheimer Disease 100%
  • Pathology 81%
  • Inclusion Bodies 49%
  • Frontotemporal Lobar Degeneration 30%
  • Apolipoprotein E4 29%
• 2020

  Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways

  Zhao, N., Ren, Y., Yamazaki, Y., Qiao, W., Li, F., Felton, L. M., Mahmoudiandehkordi, S., Kueider-Paisley, A., Sonoustoun, B., Arnold, M., Shue, F., Zheng, J., Attrebi, O. N., Martens, Y. A., Li, Z., Bastea, L., Meneses, A. D., Chen, K., Thompson, J. W., St John-Williams, L., & 12 othersTachibana, M., Aikawa, T., Oue, H., Job, L., Yamazaki, A., Liu, C. C., Storz, P., Asmann, Y. W., Ertekin-Taner, N., Kanekiyo, T., Kaddurah-Daouk, R. & Bu, G., Jun 3 2020, In: Neuron. 106, 5, p. 727-742.e6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Drive 100%
  • Metabolome 72%
  • Genotype 69%
  • Alzheimer Disease 50%
  • Apolipoprotein E2 49%
  17 Scopus citations

• APOE2: protective mechanism and therapeutic implications for Alzheimer’s disease

  Li, Z., Shue, F., Zhao, N., Shinohara, M. & Bu, G., Dec 1 2020, In: Molecular neurodegeneration. 15, 1, 63.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Apolipoprotein E2 100%
  • Alzheimer Disease 51%
  • Apolipoprotein E4 22%
  • Cerebrovascular Disorders 17%
  • Apolipoprotein E3 12%
  3 Scopus citations

• APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid

  Zhao, N., Attrebi, O. N., Ren, Y., Qiao, W., Sonustun, B., Martens, Y. A., Meneses, A. D., Li, F., Shue, F., Zheng, J., van Ingelgom, A. J., Davis, M. D., Kurti, A., Knight, J. A., Linares, C., Chen, Y., Delenclos, M., Liu, C. C., Fryer, J. D., Asmann, Y. W., & 4 othersMcLean, P. J., Dickson, D. W., Ross, O. A. & Bu, G., Feb 5 2020, In: Science translational medicine. 12, 529, eaay1809.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Synucleins 100%
  • Amyloid 62%
  • Pathology 41%
  • Dementia 18%
  • Human ApoE protein 17%
  24 Scopus citations

• Clinicopathologic and genetic features of multiple system atrophy with Lewy body disease

  Koga, S., Li, F., Zhao, N., Roemer, S. F., Ferman, T. J., Wernick, A. I., Walton, R. L., Faroqi, A. H., Graff-Radford, N. R., Cheshire, W. P., Ross, O. A. & Dickson, D. W., Jul 1 2020, In: Brain Pathology. 30, 4, p. 766-778 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Multiple System Atrophy 100%
  • Synucleins 11%
  • Pathology 7%
  • Dementia 6%
  • Synucleinopathies 5%

• Tau and apolipoprotein E modulate cerebrovascular tight junction integrity independent of cerebral amyloid angiopathy in Alzheimer's disease

  Liu, C. C., Yamazaki, Y., Heckman, M. G., Martens, Y. A., Jia, L., Yamazaki, A., Diehl, N. N., Zhao, J., Zhao, N., DeTure, M., Davis, M. D., Felton, L. M., Qiao, W., Li, Y., Li, H., Fu, Y., Wang, N., Wren, M., Aikawa, T., Holm, M. L., & 10 othersOue, H., Linares, C., Allen, M., Carrasquillo, M. M., Murray, M. E., Petersen, R. C., Ertekin-Taner, N., Dickson, D. W., Kanekiyo, T. & Bu, G., Oct 1 2020, In: Alzheimer's and Dementia. 16, 10, p. 1372-1383 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cerebral Amyloid Angiopathy 100%
  • Tight Junctions 79%
  • Apolipoproteins E 75%
  • dementia 71%
  • integrity 60%
  5 Scopus citations
• 2019

  Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies

  Yamazaki, Y., Zhao, N., Caulfield, T. R., Liu, C. C. & Bu, G., Sep 1 2019, In: Nature Reviews Neurology. 15, 9, p. 501-518 18 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Apolipoproteins E 100%
  • Alzheimer Disease 73%
  • Apolipoprotein E4 51%
  • Alleles 41%
  • Pathology 35%
  149 Scopus citations
• 2018

  APOE ε2 is associated with increased tau pathology in primary tauopathy

  Zhao, N., Liu, C. C., Van Ingelgom, A. J., Linares, C., Kurti, A., Knight, J. A., Heckman, M. G., Diehl, N. N., Shinohara, M., Martens, Y. A., Attrebi, O. N., Petrucelli, L., Fryer, J. D., Wszolek, Z. K., Graff-Radford, N. R., Caselli, R. J., Sanchez-Contreras, M. Y., Rademakers, R., Murray, M. E., Koga, S., & 3 othersDickson, D. W., Ross, O. A. & Bu, G., Dec 1 2018, In: Nature communications. 9, 1, 4388.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apolipoprotein E2 100%
  • Tauopathies 89%
  • pathology 79%
  • mice 68%
  • Human ApoE protein 53%
  49 Scopus citations

• Apolipoprotein E, Receptors, and Modulation of Alzheimer's Disease

  Zhao, N., Liu, C. C., Qiao, W. & Bu, G., Feb 15 2018, In: Biological psychiatry. 83, 4, p. 347-357 11 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Low Density Lipoprotein Receptor-Related Protein-1 100%
  • Apolipoproteins E 72%
  • Alzheimer Disease 53%
  • Lipids 19%
  • Amyloid 18%
  137 Scopus citations
• 2017

  ApoE4 Accelerates Early Seeding of Amyloid Pathology

  Liu, C. C., Zhao, N., Fu, Y., Wang, N., Linares, C., Tsai, C. W. & Bu, G., Dec 6 2017, In: Neuron. 96, 5, p. 1024-1032.e3

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apolipoprotein E4 100%
  • Amyloid 69%
  • Pathology 46%
  • Apolipoprotein E3 32%
  • Apolipoproteins E 15%
  103 Scopus citations

• Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes

  Zhao, N., Liu, C. C., Van Ingelgom, A. J., Martens, Y. A., Linares, C., Knight, J. A., Painter, M. M., Sullivan, P. M. & Bu, G., Sep 27 2017, In: Neuron. 96, 1, p. 115-129.e5

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apolipoprotein E4 100%
  • Insulin Receptor 82%
  • Endosomes 82%
  • Insulin 50%
  • Alzheimer Disease 25%
  104 Scopus citations

• Astrocytic LRP1 mediates brain Aβ clearance and impacts amyloid deposition

  Liu, C. C., Hu, J., Zhao, N., Wang, J., Wang, N., Cirrito, J. R., Kanekiyo, T., Holtzman, D. M. & Bu, G., Apr 12 2017, In: Journal of Neuroscience. 37, 15, p. 4023-4031 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Lipoprotein Receptors 100%
  • Amyloid 66%
  • Astrocytes 64%
  • Alzheimer Disease 43%
  • Brain 34%
  86 Scopus citations

• Subacute ibuprofen treatment rescues the synaptic and cognitive deficits in advanced-aged mice

  Rogers, J. T., Liu, C. C., Zhao, N., Wang, J., Putzke, T., Yang, L., Shinohara, M., Fryer, J. D., Kanekiyo, T. & Bu, G., May 1 2017, In: Neurobiology of aging. 53, p. 112-121 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ibuprofen 100%
  • Cognition 50%
  • Neuronal Plasticity 40%
  • Astrocytes 39%
  • Anti-Inflammatory Agents 31%
  15 Scopus citations
• 2016

  Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer’s disease

  Shinohara, M., Murray, M. E., Frank, R. D., Shinohara, M., DeTure, M., Yamazaki, Y., Tachibana, M., Atagi, Y., Davis, M. D., Liu, C. C., Zhao, N., Painter, M. M., Petersen, R. C., Fryer, J. D., Crook, J. E., Dickson, D. W., Bu, G. & Kanekiyo, T., Aug 1 2016, In: Acta neuropathologica. 132, 2, p. 225-234 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cerebral Amyloid Angiopathy 100%
  • Alzheimer Disease 54%
  • Apolipoproteins E 28%
  • Detergents 11%
  • Amyloid 10%
  35 Scopus citations

• Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer's disease

  Liu, C. C., Zhao, N., Yamaguchi, Y., Cirrito, J. R., Kanekiyo, T., Holtzman, D. M. & Bu, G., Mar 30 2016, In: Science translational medicine. 8, 332, 332ra44.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Heparitin Sulfate 100%
  • Amyloid 77%
  • Alzheimer Disease 63%
  • Pathology 51%
  • Brain 40%
  60 Scopus citations
• 2015

  Single-nucleotide polymorphisms and haplotypes of non-coding area in the CP gene are correlated with Parkinson’s disease

  Zhao, N., Xiao, J., Zheng, Z., Fei, G., Zhang, F., Jin, L. & Zhong, C., Apr 1 2015, In: Neuroscience Bulletin. 31, 2, p. 245-256 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ceruloplasmin 100%
  • Haplotypes 73%
  • Single Nucleotide Polymorphism 65%
  • Genes 31%
  • Luciferases 14%
• 2014

  Beneficial synergistic effects of microdose lithium with pyrroloquinoline quinone in an Alzheimer's disease mouse model

  Zhao, L., Gong, N., Liu, M., Pan, X., Sang, S., Sun, X., Yu, Z., Fang, Q., Zhao, N., Fei, G., Jin, L., Zhong, C. & Xu, T., Dec 1 2014, In: Neurobiology of aging. 35, 12, p. 2736-2745 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • PQQ Cofactor 100%
  • Lithium 62%
  • Alzheimer Disease 44%
  • Amyloid 18%
  • Transgenic Mice 17%

• Serum microRNA-133b is associated with low ceruloplasmin levels in Parkinson's disease

  Zhao, N., Jin, L., Fei, G., Zheng, Z. & Zhong, C., Nov 1 2014, In: Parkinsonism and Related Disorders. 20, 11, p. 1177-1180 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Ceruloplasmin 100%
  • MicroRNAs 65%
  • Serum 35%
  • Phenotype 6%
  • Polymerase Chain Reaction 6%
• 2013

  Spinal cord ependymoma presenting as acute paraplegia and subarachnoid hemorrhage: A case report and review of literature

  Zhao, N., Chang, J., Shao, Y. & Wei, W., Dec 2013, In: Neurology Asia. 18, 4, p. 431-434 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Ependymoma 100%
  • Paraplegia 89%
  • Subarachnoid Hemorrhage 80%
  • Spinal Cord 63%
  • Hemorrhage 37%
• 2012

  Benfotiamine prevents increased β-amyloid production in HEK cells induced by high glucose

  Sun, X. J., Zhao, L., Zhao, N., Pan, X. L., Fei, G. Q., Jin, L. R. & Zhong, C. J., Oct 2012, In: Neuroscience Bulletin. 28, 5, p. 561-566 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • benphothiamine 100%
  • Glycogen Synthase Kinase 3 53%
  • Amyloid 52%
  • Glucose 34%
  • HEK293 Cells 25%

• Nigral iron deposition occurs across motor phenotypes of Parkinson's disease

  Jin, L., Wang, J., Jin, H., Fei, G., Zhang, Y., Chen, W., Zhao, L., Zhao, N., Sun, X., Zeng, M. & Zhong, C., Jul 2012, In: European Journal of Neurology. 19, 7, p. 969-976 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Substantia Nigra 100%
  • Ceruloplasmin 95%
  • Iron 77%
  • Tremor 59%
  • Phenotype 56%
• 2008

  Impaired hippocampal neurogenesis is involved in cognitive dysfunction induced by thiamine deficiency at early pre-pathological lesion stage

  Zhao, N., Zhong, C., Wang, Y., Zhao, Y., Gong, N., Zhou, G., Xu, T. & Hong, Z., Feb 2008, In: Neurobiology of Disease. 29, 2, p. 176-185 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Thiamine Deficiency 100%
  • Neurogenesis 73%
  • Cognitive Dysfunction 56%
  • Thiamine 21%
  • Learning 19%
• 2007

  Decreased hippocampal neurogenesis is involved in cognitive dysfunction induced by thiamine deficiency

  Zhao, N., Zhong, C. J., Wang, Y., Zhao, Y. L., Zhou, G. M. & Hong, Z., May 2007, In: Chinese Journal of Neurology. 40, 5, p. 302-305 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Thiamine Deficiency 100%
  • Neurogenesis 73%
  • Cognitive Dysfunction 56%
  • Bromodeoxyuridine 55%
  • Learning 50%