Mitesh J Borad, MD

Research output

Research output per year 2003 2021

• 12219 Citations
• 49 Scopus h-Index
• 121 Article
• 18 Review article
• 5 Comment/debate
• 4 Chapter
• 5 More
  • 3 Letter
  • 1 Editorial
  • 1 Short survey

Research output per year

Research output per year

Search results

• 2021

  Aspirin and statin use and the risk of gallbladder cancer

  Prasai, K., Tella, S. H., Yadav, S., Kommalapati, A., Mara, K., Mady, M., Hassan, M. A., Wongjarupong, N., Rodriguez‐payan, N., Borad, M. J., Patel, T., Roberts, L. R. & Mahipal, A., Mar 1 2021, In: Cancers. 13, 5, p. 1-10 10 p., 1186.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gallbladder Neoplasms
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Aspirin
  • Odds Ratio
  • Logistic Models

• Circulating Tumor DNA-Based Testing and Actionable Findings in Patients with Advanced and Metastatic Pancreatic Adenocarcinoma

  Botrus, G., Kosirorek, H., Sonbol, M. B., Kusne, Y., Uson Junior, P. L. S., Borad, M. J., Ahn, D. H., Pashtoon, K. M., Drusbosky, L. M., Dada, H., Surapaneni, P. K., Starr, J., Ritter, A., McMillan, J., Wylie, N., Mody, K. & Bekaii-Saab, T. S., 2021, (Accepted/In press) In: Oncologist.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Circulating Tumor DNA
  • DNA Fingerprinting
  • Adenocarcinoma
  • Genes
  • Molecular Pathology

• Phase IB study of sorafenib and evofosfamide in patients with advanced hepatocellular and renal cell carcinomas (NCCTG N1135, Alliance)

  Tran, N. H., Foster, N. R., Mahipal, A., Byrne, T. J., Hubbard, J., Silva, A., Mody, K., Alberts, S. & Borad, M. J., 2021, (Accepted/In press) In: Investigational New Drugs.

  Research output: Contribution to journal › Article › peer-review

  • TH 302
  • Sorafenib
  • Renal Cell Carcinoma
  • Hepatocellular Carcinoma
  • Maximum Tolerated Dose
• 2020

  BL-8040, a CXCR4 antagonist, in combination with pembrolizumab and chemotherapy for pancreatic cancer: the COMBAT trial

  Bockorny, B., Semenisty, V., Macarulla, T., Borazanci, E., Wolpin, B. M., Stemmer, S. M., Golan, T., Geva, R., Borad, M. J., Pedersen, K. S., Park, J. O., Ramirez, R. A., Abad, D. G., Feliu, J., Muñoz, A., Ponz-Sarvise, M., Peled, A., Lustig, T. M., Bohana-Kashtan, O., Shaw, S. M. & 6 others, Sorani, E., Chaney, M., Kadosh, S., Vainstein Haras, A., Von Hoff, D. D. & Hidalgo, M., Jun 1 2020, In: Nature Medicine. 26, 6, p. 878-885 8 p.

  Research output: Contribution to journal › Article › peer-review

  • 4-fluorobenzoyl-TN-14003
  • Chemotherapy
  • pembrolizumab
  • CXCR4 Receptors
  • Disease control
  28 Scopus citations

• Evaluation of NUC-1031: a first-in-class ProTide in biliary tract cancer

  Arora, M., Bogenberger, J. M., Abdelrahman, A., Leiting, J. L., Chen, X., Egan, J. B., Kasimsetty, A., Lenkiewicz, E., Malasi, S., Uson, P. L. S., Nagalo, B. M., Zhou, Y., Salomao, M. A., Kosiorek, H. E., Braggio, E., Barrett, M. T., Truty, M. J. & Borad, M. J., Jun 1 2020, In: Cancer chemotherapy and pharmacology. 85, 6, p. 1063-1078 16 p.

  Research output: Contribution to journal › Article › peer-review

  • NUC-1031
  • Biliary Tract Neoplasms
  • gemcitabine
  • Cytidine Deaminase
  • Cisplatin
  4 Scopus citations

• Genomic profiling reveals high frequency of DNA repair genetic aberrations in gallbladder cancer

  Abdel-Wahab, R., Yap, T. A., Madison, R., Pant, S., Cooke, M., Wang, K., Zhao, H., Bekaii-Saab, T., Karatas, E., Kwong, L. N., Meric-Bernstam, F., Borad, M. & Javle, M., Dec 2020, In: Scientific reports. 10, 1, 22087.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gallbladder Neoplasms
  • DNA Repair
  • Genes
  • Tumor Burden
  • Microsatellite Instability
  2 Scopus citations

• Integration of Comprehensive Genomic Analysis and Functional Screening of Affected Molecular Pathways to Inform Cancer Therapy

  Vasmatzis, G., Liu, M. C., Reganti, S., Feathers, R. W., Smadbeck, J., Johnson, S. H., Schaefer Klein, J. L., Harris, F. R., Yang, L., Kosari, F., Murphy, S. J., Borad, M. J., Thompson, E. A., Cheville, J. C. & Anastasiadis, P. Z., Feb 2020, In: Mayo Clinic proceedings. 95, 2, p. 306-318 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neoplasms
  • Mutation
  • Afatinib
  • Therapeutics
  • Data Visualization
  2 Scopus citations

• Ivosidenib in IDH1-mutant, chemotherapy-refractory cholangiocarcinoma (ClarIDHy): a multicentre, randomised, double-blind, placebo-controlled, phase 3 study

  Abou-Alfa, G. K., Macarulla, T., Javle, M. M., Kelley, R. K., Lubner, S. J., Adeva, J., Cleary, J. M., Catenacci, D. V., Borad, M. J., Bridgewater, J., Harris, W. P., Murphy, A. G., Oh, D. Y., Whisenant, J., Lowery, M. A., Goyal, L., Shroff, R. T., El-Khoueiry, A. B., Fan, B., Wu, B. & 6 others, Chamberlain, C. X., Jiang, L., Gliser, C., Pandya, S. S., Valle, J. W. & Zhu, A. X., Jun 2020, In: The Lancet Oncology. 21, 6, p. 796-807 12 p.

  Research output: Contribution to journal › Article › peer-review

  • ivosidenib
  • Isocitrate Dehydrogenase
  • Cholangiocarcinoma
  • Placebos
  • Drug Therapy
  78 Scopus citations

• Neutrophil to lymphocyte ratio as a prognostic marker in metastatic gallbladder cancer

  Mady, M., Prasai, K., Tella, S. H., Yadav, S., Hallemeier, C. L., Rakshit, S., Roberts, L., Borad, M. & Mahipal, A., Oct 2020, In: HPB. 22, 10, p. 1490-1495 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Gallbladder Neoplasms
  • Neutrophils
  • Lymphocytes
  • Survival
  • Drug Therapy
  2 Scopus citations

• Novel staging system using carbohydrate antigen (CA) 19-9 in extra-hepatic cholangiocarcinoma and its implications on overall survival: CA19-9 in the staging of extra-hepatic cholangiocarcinoma

  Tella, S. H., Kommalapati, A., Yadav, S., Bergquist, J. R., Goyal, G., Durgin, L., Borad, M., Cleary, S. P., Truty, M. J. & Mahipal, A., May 2020, In: European Journal of Surgical Oncology. 46, 5, p. 789-795 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Cholangiocarcinoma
  • Carbohydrates
  • Antigens
  • Survival
  • Liver
  3 Scopus citations

• Oncolytic Virus with Attributes of Vesicular Stomatitis Virus and Measles Virus in Hepatobiliary and Pancreatic Cancers

  Nagalo, B. M., Breton, C. A., Zhou, Y., Arora, M., Bogenberger, J. M., Barro, O., Steele, M. B., Jenks, N. J., Baker, A. T., Duda, D. G., Roberts, L. R., Russell, S. J., Peng, K. W. & Borad, M. J., Sep 25 2020, In: Molecular Therapy - Oncolytics. 18, p. 546-555 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oncolytic Viruses
  • Vesicular Stomatitis
  • Measles virus
  • Pancreatic Neoplasms
  • Hemagglutinins
  1 Scopus citations

• Pemigatinib for previously treated, locally advanced or metastatic cholangiocarcinoma: a multicentre, open-label, phase 2 study

  Abou-Alfa, G. K., Sahai, V., Hollebecque, A., Vaccaro, G., Melisi, D., Al-Rajabi, R., Paulson, A. S., Borad, M. J., Gallinson, D., Murphy, A. G., Oh, D. Y., Dotan, E., Catenacci, D. V., Van Cutsem, E., Ji, T., Lihou, C. F., Zhen, H., Féliz, L. & Vogel, A., May 2020, In: The Lancet Oncology. 21, 5, p. 671-684 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Cholangiocarcinoma
  • Fibroblast Growth Factor Receptors
  • Disease Progression
  • Abdominal Pain
  • Receptor, Fibroblast Growth Factor, Type 2
  129 Scopus citations

• Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours

  Hong, D. S., Kang, Y. K., Borad, M., Sachdev, J., Ejadi, S., Lim, H. Y., Brenner, A. J., Park, K., Lee, J. L., Kim, T. Y., Shin, S., Becerra, C. R., Falchook, G., Stoudemire, J., Martin, D., Kelnar, K., Peltier, H., Bonato, V., Bader, A. G., Smith, S. & 3 others, Kim, S., O’Neill, V. & Beg, M. S., May 26 2020, In: British journal of cancer. 122, 11, p. 1630-1637 8 p.

  Research output: Contribution to journal › Article › peer-review

  • MicroRNAs
  • Premedication
  • Neoplasms
  • Dexamethasone
  • Chills
  56 Scopus citations

• Phase 1 trial of Vismodegib and Erlotinib combination in metastatic pancreatic cancer

  McCleary-Wheeler, A. L., Carr, R. M., Palmer, S. R., Smyrk, T. C., Allred, J. B., Almada, L. L., Tolosa, E. J., Lamberti, M. J., Marks, D. L., Borad, M. J., Molina, J. R., Qi, Y., Lingle, W. L., Grothey, A., Pitot, H. C., Jatoi, A., Northfelt, D. W., Bryce, A. H., McWilliams, R. R., Okuno, S. H. & 10 others, Haluska, P., Kim, G. P., Colon-Otero, G., Lowe, V. J., Callstrom, M. R., Ma, W. W., Bekaii-Saab, T., Hung, M. C., Erlichman, C. & Fernandez-Zapico, M. E., Jan 2020, In: Pancreatology. 20, 1, p. 101-109 9 p.

  Research output: Contribution to journal › Article › peer-review

  • HhAntag691
  • Erlotinib Hydrochloride
  • Pancreatic Neoplasms
  • Hedgehogs
  • Adenocarcinoma
  3 Scopus citations

• Phase II Trial of Trifluridine/Tipiracil in Patients with Advanced, Refractory Biliary Tract Carcinoma

  Chakrabarti, S., Zemla, T. J., Ahn, D. H., Ou, F. S., Fruth, B., Borad, M. J., Hartgers, M. L., Wessling, J., Walkes, R. L., Alberts, S. R., McWilliams, R. R., Liu, M. C., Durgin, L. M., Bekaii-Saab, T. S. & Mahipal, A., May 1 2020, In: Oncologist. 25, 5, p. 380-e763

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • trifluridine tipiracil
  • Biliary Tract
  • Carcinoma
  • Progression-Free Survival
  • Confidence Intervals
  3 Scopus citations

• Targeting of the Hedgehog/GLI and mTOR pathways in advanced pancreatic cancer, a phase 1 trial of Vismodegib and Sirolimus combination

  Carr, R. M., Duma, N., McCleary-Wheeler, A. L., Almada, L. L., Marks, D. L., Graham, R. P., Smyrk, T. C., Lowe, V., Borad, M. J., Kim, G., Johnson, G. B., Allred, J. B., Yin, J., Lim, V. S., Bekaii-Saab, T., Ma, W. W., Erlichman, C., Adjei, A. A. & Fernandez-Zapico, M. E., Sep 2020, In: Pancreatology. 20, 6, p. 1115-1122 8 p.

  Research output: Contribution to journal › Article › peer-review

  • HhAntag691
  • Sirolimus
  • Pancreatic Neoplasms
  • Maximum Tolerated Dose
  • Thrombocytopenia
  1 Scopus citations

• The Role of Maintenance Strategies in Metastatic Colorectal Cancer: A Systematic Review and Network Meta-analysis of Randomized Clinical Trials

  Sonbol, M. B., Mountjoy, L. J., Firwana, B., Liu, A. J., Almader-Douglas, D., Mody, K., Hubbard, J., Borad, M., Ahn, D. H., Murad, M. H. & Bekaii-Saab, T., Mar 2020, In: JAMA Oncology. 6, 3

  Research output: Contribution to journal › Article › peer-review

  • Network Meta-Analysis
  • Bevacizumab
  • Colorectal Neoplasms
  • Systematic Reviews
  • Maintenance
  7 Scopus citations
• 2019

  A phase I study of the safety and tolerability of VLX600, an Iron Chelator, in patients with refractory advanced solid tumors

  Mody, K., Mansfield, A. S., Vemireddy, L., Nygren, P., Gulbo, J. & Borad, M., Aug 15 2019, In: Investigational New Drugs. 37, 4, p. 684-692 9 p.

  Research output: Contribution to journal › Article › peer-review

  • VLX600
  • Chelating Agents
  • Iron
  • Safety
  • Maximum Tolerated Dose
  8 Scopus citations

• Association between treatment facility volume, therapy types and overall survival in patients with intrahepatic cholangiocarcinoma

  Kommalapati, A., Tella, S. H., Goyal, G., Borad, M., Alberts, S. R., Roberts, L., Hubbard, J. M., Durgin, L., Cleary, S. & Mahipal, A., Mar 2019, In: HPB. 21, 3, p. 379-386 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Cholangiocarcinoma
  • Survival
  • Liver
  • Therapeutics
  • Insurance
  2 Scopus citations

• Clinicopathological features and outcomes of fibrolamellar hepatocellular carcinoma

  Chakrabarti, S., Tella, S. H., Kommalapati, A., Huffman, B. M., Yadav, S., Riaz, I. B., Goyal, G., Mody, K., Borad, M., Cleary, S., Smoot, R. L. & Mahipal, A., 2019, In: Journal of Gastrointestinal Oncology. 10, 3, p. 554-561 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Fibrolamellar hepatocellular carcinoma
  • Survival
  • Sorafenib
  • Recurrence
  • Nivolumab
  10 Scopus citations

• Decline in the seroprevalence of syphilis markers among first-time blood donors in Libreville (Gabon) between 2004 and 2016

  Bisseye, C., Eko Mba, J. M., Ntsame Ndong, J. M., Kosiorek, H. E., Butterfield, R. J., Mombo, L. E., M'Batchi, B., Borad, M. J., Nagalo, B. M. & Allain, J. P., Feb 8 2019, In: BMC Public Health. 19, 1, 167.

  Research output: Contribution to journal › Article › peer-review

  • Gabon
  • Syphilis
  • Seroepidemiologic Studies
  • Blood Donors
  • Odds Ratio

• E6201, an intravenous MEK1 inhibitor, achieves an exceptional response in BRAF V600E-mutated metastatic malignant melanoma with brain metastases

  Babiker, H. M., Byron, S. A., Hendricks, W. P. D., Elmquist, W. F., Gampa, G., Vondrak, J., Aldrich, J., Cuyugan, L., Adkins, J., De Luca, V., Tibes, R., Borad, M. J., Marceau, K., Myers, T. J., Paradiso, L. J., Liang, W. S., Korn, R. L., Cridebring, D., Von Hoff, D. D., Carpten, J. D. & 3 others, Craig, D. W., Trent, J. M. & Gordon, M. S., Aug 15 2019, In: Investigational New Drugs. 37, 4, p. 636-645 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Melanoma
  • Neoplasm Metastasis
  • Brain
  • Whole Exome Sequencing
  • Blood-Brain Barrier
  10 Scopus citations

• Feasibility of circulating tumor DNA testing in hepatocellular carcinoma

  Mody, K., Kasi, P. M., Yang, J. D., Surapaneni, P. K., Ritter, A., Roberts, A., Nagy, R. & Borad, M. J., 2019, In: Journal of Gastrointestinal Oncology. 10, 4, p. 745-750 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Circulating Tumor DNA
  • Hepatocellular Carcinoma
  • Neoplasms
  • Biliary Tract Neoplasms
  • Technology
  5 Scopus citations

• Gemcitabine, Cisplatin, and nab-Paclitaxel for the Treatment of Advanced Biliary Tract Cancers: A Phase 2 Clinical Trial

  Shroff, R. T., Javle, M. M., Xiao, L., Kaseb, A. O., Varadhachary, G. R., Wolff, R. A., Raghav, K. P. S., Iwasaki, M., Masci, P., Ramanathan, R. K., Ahn, D. H., Bekaii-Saab, T. S. & Borad, M. J., Jun 2019, In: JAMA Oncology. 5, 6, p. 824-830 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Albumin-Bound Paclitaxel
  • Biliary Tract Neoplasms
  • gemcitabine
  • Nanoparticles
  • Cisplatin
  73 Scopus citations

• Hepatocytes direct the formation of a pro-metastatic niche in the liver

  Lee, J. W., Stone, M. L., Porrett, P. M., Thomas, S. K., Komar, C. A., Li, J. H., Delman, D., Graham, K., Gladney, W. L., Hua, X., Black, T. A., Chien, A. L., Majmundar, K. S., Thompson, J. C., Yee, S. S., O’Hara, M. H., Aggarwal, C., Xin, D., Shaked, A., Gao, M. & 9 others, Liu, D., Borad, M. J., Ramanathan, R. K., Carpenter, E. L., Ji, A., de Beer, M. C., de Beer, F. C., Webb, N. R. & Beatty, G. L., Mar 14 2019, In: Nature. 567, 7747, p. 249-252 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Hepatocytes
  • Liver
  • STAT3 Transcription Factor
  • Circulating Neoplastic Cells
  • Neoplasm Metastasis
  80 Scopus citations

• HSP90 Inhibition Drives Degradation of FGFR2 Fusion Proteins: Implications for Treatment of Cholangiocarcinoma

  Lamberti, D., Cristinziano, G., Porru, M., Leonetti, C., Egan, J. B., Shi, C. X., Buglioni, S., Amoreo, C. A., Castellani, L., Borad, M. J., Alemà, S., Anastasi, S. & Segatto, O., Jan 2019, In: Hepatology. 69, 1, p. 131-142 12 p.

  Research output: Contribution to journal › Article › peer-review

  • STA 9090
  • 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-(4-(4-ethylpiperazin-1-yl)-phenylamino)pyrimidin-4-yl)-1-methylurea
  • Receptor, Fibroblast Growth Factor, Type 2
  • HSP90 Heat-Shock Proteins
  • Cholangiocarcinoma
  9 Scopus citations

• MetaMarker: A pipeline for de novo discovery of novel metagenomic biomarkers

  Koohi-Moghadam, M., Borad, M. J., Tran, N. L., Swanson, K. R., Boardman, L. A., Sun, H. & Wang, J., Oct 1 2019, In: Bioinformatics. 35, 19, p. 3812-3814 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Biomarkers
  • Metagenomics
  • Colorectal Cancer
  • Pipelines
  • Colorectal Neoplasms
  1 Scopus citations

• Neoadjuvant vs. adjuvant chemotherapy for cholangiocarcinoma: A propensity score matched analysis

  Yadav, S., Xie, H., Bin-Riaz, I., Sharma, P., Durani, U., Goyal, G., Borah, B., Borad, M. J., Smoot, R. L., Roberts, L. R., Go, R. S., McWilliams, R. R. & Mahipal, A., Aug 2019, In: European Journal of Surgical Oncology. 45, 8, p. 1432-1438 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Cholangiocarcinoma
  • Adjuvant Chemotherapy
  • Drug Therapy
  • Survival
  • Databases
  14 Scopus citations

• Preclinical In Vitro and In Vivo Evidence of an Antitumor Effect of CX-4945, a Casein Kinase II Inhibitor, in Cholangiocarcinoma

  Zakharia, K., Miyabe, K., Wang, Y., Wu, D., Moser, C. D., Borad, M. J. & Roberts, L. R., Jan 2019, In: Translational Oncology. 12, 1, p. 143-153 11 p.

  Research output: Contribution to journal › Article › peer-review

  • 5-(3-chlorophenylamino)benzo(c)(2,6)naphthyridine-8-carboxylic acid
  • Casein Kinase II
  • Cholangiocarcinoma
  • gemcitabine
  • Cisplatin
  12 Scopus citations

• Prognostic subclass of intrahepatic cholangiocarcinoma by integrative molecular–clinical analysis and potential targeted approach

  Ahn, K. S., O’Brien, D., Kang, Y. N., Mounajjed, T., Kim, Y. H., Kim, T. S., Kocher, J. P. A., Allotey, L. K., Borad, M. J., Roberts, L. R. & Kang, K. J., Jul 1 2019, In: Hepatology International. 13, 4, p. 490-500 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cholangiocarcinoma
  • RNA Sequence Analysis
  • Pathology
  • Cholangitis
  • Carcinoembryonic Antigen
  5 Scopus citations

• Treating HER2-mutant advanced biliary tract cancer with neratinib: benefits of HER2-directed targeted therapy in the phase 2 SUMMIT 'basket' trial

  Harding, J., Cleary, J., Shapiro, G., Braña, I., Moreno, V., Quinn, D., Borad, M., Loi, S., Spanggaard, I., Stemmer, S., Dujka, M., Cutler, R., Xu, F., Eli, L., Macia, S., Lalani, A., Bryce, R., Bernstam, F. M., Solit, D., Hyman, D. & 1 others, Piha-Paul, S., Jul 1 2019, In: Annals of oncology : official journal of the European Society for Medical Oncology. 30, p. iv127

  Research output: Contribution to journal › Article › peer-review
• 2018

  A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

  The Cancer Genome Atlas Research Network, Apr 9 2018, In: Cancer cell. 33, 4, p. 690-705.e9

  Research output: Contribution to journal › Article › peer-review

  • Atlases
  • Breast Neoplasms
  • Decision Trees
  • Long Noncoding RNA
  • Genome
  150 Scopus citations

• Adjuvant systemic therapy after resection of node positive gallbladder cancer: Time for a well-designed trial? (Results of a US-national retrospective cohort study)

  Bergquist, J. R., Shah, H. N., Habermann, E. B., Hernandez, M. C., Ivanics, T., Kendrick, M. L., Smoot, R. L., Nagorney, D. M., Borad, M. J., McWilliams, R. R. & Truty, M. J., Apr 2018, In: International Journal of Surgery. 52, p. 171-179 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Gallbladder Neoplasms
  • Cohort Studies
  • Retrospective Studies
  • Gallbladder
  • Adjuvant Chemotherapy
  20 Scopus citations

• An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

  The Cancer Genome Atlas Research Network, Apr 5 2018, In: Cell. 173, 2, p. 400-416.e11

  Research output: Contribution to journal › Article › peer-review

  • Atlases
  • Genes
  • Genome
  • Survival
  • Neoplasms
  523 Scopus citations

• A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples

  The Cancer Genome Atlas Research Network, Apr 5 2018, In: Cell. 173, 2, p. 386-399.e12

  Research output: Contribution to journal › Article › peer-review

  • Genes
  • Tumors
  • Neoplasms
  • Computational methods
  • Chemical activation
  82 Scopus citations

• A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily

  The Cancer Genome Atlas Research Network, Oct 24 2018, In: Cell Systems. 7, 4, p. 422-437.e7

  Research output: Contribution to journal › Article › peer-review

  • Transforming Growth Factors
  • Sequence Deletion
  • Neoplasms
  • Genes
  • Transforming Growth Factor-beta Type II Receptors
  43 Scopus citations

• A phase IIa trial to assess the safety and efficacy of BL-8040 and pembrolizumab in patients with metastatic pancreatic adenocarcinoma (PDAC)

  Hidalgo, M., Epelbaum, R., Wolpin, B. M., Stemmer, S. M., Geva, R., Golan, T., Borazanci, E., Borad, M., Pedersen, K. S., Park, J. O., Ramirez, R., Peled, A., Lustig, T. M., Bohana Kashtan, O., Rosenfeld, O., Sorani, E., Schlienger, K., Vainstein Haras, A. & Von Hoff, D. D., Oct 1 2018, In: Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. viii402

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

  The Cancer Genome Atlas Network, Apr 5 2018, In: Cell. 173, 2, p. 291-304.e6

  Research output: Contribution to journal › Article › peer-review

  • Tumors
  • Tissue
  • DNA Methylation
  • Methylation
  • Histology
  468 Scopus citations

• Chromoanasynthesis is a common mechanism that leads to ERBB2 amplifications in a cohort of early stage HER2 ⁺ breast cancer samples

  Vasmatzis, G., Wang, X., Smadbeck, J. B., Murphy, S. J., Geiersbach, K. B., Johnson, S. H., Gaitatzes, A. G., Asmann, Y. W., Kosari, F., Borad, M. J., Serie, D. J., McLaughlin, S. A., Kachergus, J. M., Necela, B. M. & Aubrey Thompson, E., Jul 13 2018, In: BMC cancer. 18, 1, 738.

  Research output: Contribution to journal › Article › peer-review

  • Chromosomes, Human, Pair 8
  • Breast Neoplasms
  • Chromosomes, Human, Pair 17
  • Whole Exome Sequencing
  • Whole Genome Sequencing
  3 Scopus citations

• Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas

  The Cancer Genome Atlas Research Network, Apr 9 2018, In: Cancer cell. 33, 4, p. 721-735.e8

  Research output: Contribution to journal › Article › peer-review

  • Adenocarcinoma
  • Genome
  • Chromosomal Instability
  • Neoplasms
  • Rectum
  127 Scopus citations

• Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

  The Cancer Genome Atlas Research Network, Aug 13 2018, In: Cancer cell. 34, 2, p. 211-224.e6

  Research output: Contribution to journal › Article › peer-review

  • Alternative Splicing
  • Neoplasms
  • Exons
  • Peptides
  • Whole Exome Sequencing
  185 Scopus citations

• Comprehensive Characterization of Cancer Driver Genes and Mutations

  The MC3 Working Group & The Cancer Genome Atlas Research Network, Apr 5 2018, In: Cell. 173, 2, p. 371-385.e18

  Research output: Contribution to journal › Article › peer-review

  • Neoplasm Genes
  • Tumors
  • Genes
  • Mutation
  • Neoplasms
  509 Scopus citations

• Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer

  The Cancer Genome Atlas Research Network, Oct 30 2018, In: Cell reports. 25, 5, p. 1304-1317.e5

  Research output: Contribution to journal › Article › peer-review

  • Genes
  • Epithelial Cells
  • Neoplasms
  • Tumors
  • Squamous Cell Neoplasms
  81 Scopus citations

• Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

  The Fusion Analysis Working Group & The Cancer Genome Atlas Research Network, Apr 3 2018, In: Cell reports. 23, 1, p. 227-238.e3

  Research output: Contribution to journal › Article › peer-review

  • Human Development
  • Fusion reactions
  • Gene Fusion
  • Phosphotransferases
  • Neoplasms
  150 Scopus citations

• Evaluation of pre-analytical factors affecting plasma DNA analysis

  Markus, H., Contente-Cuomo, T., Farooq, M., Liang, W. S., Borad, M. J., Sivakumar, S., Gollins, S., Tran, N. L., Dhruv, H. D., Berens, M. E., Bryce, A., Sekulic, A., Ribas, A., Trent, J. M., Lorusso, P. M. & Murtaza, M., Dec 1 2018, In: Scientific reports. 8, 1, 7375.

  Research output: Contribution to journal › Article › peer-review

  • Cell-Free Nucleic Acids
  • DNA
  • Phlebotomy
  • Polymerase Chain Reaction
  • Edetic Acid
  48 Scopus citations

• Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

  The Cancer Genome Atlas Research Network, Apr 3 2018, In: Cell reports. 23, 1, p. 194-212.e6

  Research output: Contribution to journal › Article › peer-review

  • Epithelial Cells
  • Squamous Cell Carcinoma
  • MicroRNAs
  • Mutation
  • Ports and harbors
  86 Scopus citations

• Genomic and Functional Approaches to Understanding Cancer Aneuploidy

  The Cancer Genome Atlas Research Network, Apr 9 2018, In: Cancer cell. 33, 4, p. 676-689.e3

  Research output: Contribution to journal › Article › peer-review

  • Aneuploidy
  • Chromosomes
  • Neoplasms
  • Mutation Rate
  • Genome
  176 Scopus citations

• Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

  The Cancer Genome Atlas Research Network, Apr 3 2018, In: Cell reports. 23, 1, p. 239-254.e6

  Research output: Contribution to journal › Article › peer-review

  • DNA Repair-Deficiency Disorders
  • Atlases
  • Genes
  • DNA Damage
  • Repair
  210 Scopus citations

• HALO 110-101: Phase Ib study of PEGPH20 in combination with cisplatin + gemcitabine (PEGCISGEM) or atezolizumab (ATEZO) + CIS + GEM (PEGCISGEMATEZO) in patients with locally advanced/metastatic cholangiocarcinoma and gallbladder cancer

  Oh, D. Y., Park, J. O., Charoentum, C., Stein, S., Noel, M., Chung, V., Wu, W., Alton, R., Muhsin, M., Javle, M., Abou-Alfa, G. K. & Borad, M. J., Nov 1 2018, In: Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. ix66

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

  The Cancer Genome Atlas Research Network, Apr 3 2018, In: Cell reports. 23, 1, p. 213-226.e3

  Research output: Contribution to journal › Article › peer-review

  • Ubiquitin
  • Genes
  • Neoplasms
  • Tumors
  • Deubiquitinating Enzymes
  32 Scopus citations