Mitesh J Borad

2022

A multicenter phase 1/2 study investigating the safety, pharmacokinetics, pharmacodynamics and efficacy of a small molecule antimetabolite, RX-3117, plus nab-paclitaxel in pancreatic adenocarcinoma

Babiker, H., Schlegel, P. J., Hicks, L. G., Bullock, A. J., Burhani, N., Mahadevan, D., Elquza, E., Borad, M. J., Benaim, E., Peterson, C., Heaton, C. & Ocean, A. J., Feb 2022, In: Investigational New Drugs. 40, 1, p. 81-90 10 p.

Research output: Contribution to journal › Article › peer-review

A pilot study of Pan-FGFR inhibitor ponatinib in patients with FGFR-altered advanced cholangiocarcinoma

Ahn, D. H., Uson Junior, P. L. S., Masci, P., Kosiorek, H., Halfdanarson, T. R., Mody, K., Babiker, H., DeLeon, T., Sonbol, M. B., Gores, G., Smoot, R., Bekaii-Saab, T., Mahipal, A., Mansfield, A., Tran, N. H., Hubbard, J. M. & Borad, M. J., Feb 2022, In: Investigational New Drugs. 40, 1, p. 134-141 8 p.

Research output: Contribution to journal › Article › peer-review

Aspirin, Statins, Non-aspirin NSAIDs, Metformin, and the Risk of Biliary Cancer: A Swedish Population-Based Cohort Study

Marcano-Bonilla, L., Schleck, C. D., Harmsen, W. S., Sadr-Azodi, O., Borad, M. J., Patel, T., Petersen, G. M., Therneau, T. M., Roberts, L. R. & Brusselaers, N., Apr 2022, In: Cancer Epidemiology Biomarkers and Prevention. 31, 4, p. 804-810 7 p.

Research output: Contribution to journal › Article › peer-review

Circulating Cell-Free Tumor DNA in Advanced Pancreatic Adenocarcinoma Identifies Patients With Worse Overall Survival

Botrus, G., Uson Junior, P. L. S., Raman, P., Kaufman, A. E., Kosiorek, H., Yin, J., Fu, Y., Majeed, U., Sonbol, M. B., Ahn, D. H., Chang, I. W., Drusbosky, L. M., Dada, H., Starr, J., Borad, M., Mody, K. & Bekaii-Saab, T. S., Jan 10 2022, In: Frontiers in Oncology. 11, 794009.

Research output: Contribution to journal › Article › peer-review

Open Access

Clinical outcomes for hilar and extrahepatic cholangiocarcinoma with adjuvant, definitive, or liver transplant-based neoadjuvant chemoradiotherapy strategies: a single-center experience

Laughlin, B. S., Petersen, M. M., Yu, N. Y., Anderson, J. D., Rule, W. G., Borad, M. J., Aqel, B. A., Sonbol, M. B., Mathur, A. K., Moss, A. A., Bekaii-Saab, T. S., Ahn, D. H., DeWees, T. A., Sio, T. T. & Ashman, J. B., Feb 2022, In: Journal of Gastrointestinal Oncology. 13, 1, p. 288-297 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

FGFR2-IIIb Expression by Immunohistochemistry Has High Specificity in Cholangiocarcinoma with FGFR2 Genomic Alterations

Uson Junior, P. L. S., DeLeon, T. T., Bogenberger, J. M., Pai, R. K., Kosiorek, H. E., Yin, J., Ahn, D. H., Sonbol, M. B., Bekaii-Saab, T., Mansfield, A. S., Buetow, K., Gores, G. J., Smoot, R., Vasmatzis, G., Kipp, B. R., Mahipal, A., Baker, A. T., Babiker, H., Barro, O., Dumbauld, C., & 11 othersZhou, Y., Aslam, F. N., Barrett, M., Jacobs, B., Meurice, N., Arora, M., Petit, J., Elliott, N., Nagalo, B., Salomao, M. A. & Borad, M. J., Aug 2022, In: Digestive diseases and sciences. 67, 8, p. 3797-3805 9 p.

Research output: Contribution to journal › Article › peer-review

Germline Cancer Susceptibility Gene Testing in Unselected Patients With Colorectal Adenocarcinoma: A Multicenter Prospective Study

Uson, P. L. S., Riegert-Johnson, D., Boardman, L., Kisiel, J., Mountjoy, L., Patel, N., Lizaola-Mayo, B., Borad, M. J., Ahn, D., Sonbol, M. B., Jones, J., Leighton, J. A., Gurudu, S., Singh, H., Klint, M., Kunze, K. L., Golafshar, M. A., Esplin, E. D., Nussbaum, R. L., Stewart, A. K., & 2 othersBekaii-Saab, T. S. & Jewel Samadder, N., Mar 2022, In: Clinical Gastroenterology and Hepatology. 20, 3, p. e508-e528

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Germline Cancer Susceptibility Gene Testing in Unselected Patients with Hepatobiliary Cancers: A Multi-Center Prospective Study

Uson, P. L. S., Kunze, K. L., Golafshar, M. A., Riegert-Johnson, D., Boardman, L., Borad, M. J., Ahn, D., Sonbol, M. B., Faigel, D. O., Fukami, N., Pannala, R., Barrus, K., Mountjoy, L., Esplin, E. D., Nussbaum, R. L., Stewart, A. K., Bekaii-Saab, T. & Samadder, N. J., Feb 2022, In: Cancer Prevention Research. 15, 2, p. 121-128 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Germline Cancer Testing in Unselected Patients with Gastric and Esophageal Cancers: A Multi-center Prospective Study

Uson, P. L. S., Kunze, K. L., Golafshar, M. A., Botrus, G., Riegert-Johnson, D., Boardman, L., Borad, M. J., Ahn, D., Sonbol, M. B., Kahn, A., Klint, M., Esplin, E. D., Nussbaum, R. L., Stewart, A. K., Bekaii-Saab, T. & Samadder, N. J., 2022, (Accepted/In press) In: Digestive diseases and sciences.

Research output: Contribution to journal › Article › peer-review

Open Access

Impact of FGFR2 gene fusions on survival of patients with intrahepatic cholangiocarcinoma following curative intent resection

Buckarma, E. LN., De La Cruz, G., Truty, M., Nagorney, D., Cleary, S., Kendrick, M., Borad, M., Graham, R., Gores, G. & Smoot, R., 2022, (Accepted/In press) In: HPB.

Research output: Contribution to journal › Article › peer-review

Isocitrate Dehydrogenase–Mutated Cholangiocarcinoma: Natural History and Clinical Outcomes

Wintheiser, G., Zemla, T., Shi, Q., Tran, N., Prasai, K., Tella, S. H., Mody, K., Ahn, D., Borad, M., Bekaii-Saab, T. & Mahipal, A., 2022, In: JCO Precision Oncology. 6, e2100156.

Research output: Contribution to journal › Article › peer-review

Outcomes following FGFR Inhibitor Therapy in Patients with Cholangiocarcinoma

Gile, J. J., Wookey, V., Zemla, T. J., Shi, Q., Jin, Z., Alberts, S. R., McWilliams, R. R., Ma, W. W., Borad, M., Bekaii-Saab, T. S., Tran, N. H. & Mahipal, A., 2022, (Accepted/In press) In: Targeted Oncology.

Research output: Contribution to journal › Article › peer-review

Placental growth factor promotes tumour desmoplasia and treatment resistance in intrahepatic cholangiocarcinoma

Aoki, S., Inoue, K., Klein, S., Halvorsen, S., Chen, J., Matsui, A., Nikmaneshi, M. R., Kitahara, S., Hato, T., Chen, X., Kawakubo, K., Nia, H. T., Chen, I., Schanne, D. H., Mamessier, E., Shigeta, K., Kikuchi, H., Ramjiawan, R. R., Schmidt, T. C. E., Iwasaki, M., & 13 othersYau, T., Hong, T. S., Quaas, A., Plum, P. S., Dima, S., Popescu, I., Bardeesy, N., Munn, L. L., Borad, M. J., Sassi, S., Jain, R. K., Zhu, A. X. & Duda, D. G., Jan 1 2022, In: Gut. 71, 1, p. 185-193 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Somatic Genomic Testing in Patients With Metastatic or Advanced Cancer: ASCO Provisional Clinical Opinion

Chakravarty, D., Johnson, A., Sklar, J., Lindeman, N. I., Moore, K., Ganesan, S., Lovly, C. M., Perlmutter, J., Gray, S. W., Hwang, J., Lieu, C., André, F., Azad, N., Borad, M., Tafe, L., Messersmith, H., Robson, M. & Meric-Bernstam, F., Apr 10 2022, In: Journal of Clinical Oncology. 40, 11, p. 1231-1258 28 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Synergistic combination of cytotoxic chemotherapy and cyclin-dependent kinase 4/6 inhibitors in biliary tract cancers

Arora, M., Bogenberger, J. M., Abdelrahman, A. M., Yonkus, J., Alva-Ruiz, R., Leiting, J. L., Chen, X., Serrano Uson Junior, P. L., Dumbauld, C. R., Baker, A. T., Gamb, S. I., Egan, J. B., Zhou, Y., Nagalo, B. M., Meurice, N., Eskelinen, E. L., Salomao, M. A., Kosiorek, H. E., Braggio, E., Barrett, M. T., & 8 othersBuetow, K. H., Sonbol, M. B., Mansfield, A. S., Roberts, L. R., Bekaii-Saab, T. S., Ahn, D. H., Truty, M. J. & Borad, M. J., Jan 2022, In: Hepatology. 75, 1, p. 43-58 16 p.

Research output: Contribution to journal › Article › peer-review

Tilsotolimod: an investigational synthetic toll-like receptor 9 (TLR9) agonist for the treatment of refractory solid tumors and melanoma

Karime, C., Wang, J., Woodhead, G., Mody, K., Hennemeyer, C. T., Borad, M. J., Mahadevan, D., Chandana, S. R. & Babiker, H., 2022, In: Expert Opinion on Investigational Drugs. 31, 1, p. 1-13 13 p.

Research output: Contribution to journal › Article › peer-review

Tumor Junction Burden and Antigen Presentation as Predictors of Survival in Mesothelioma Treated With Immune Checkpoint Inhibitors

Kosari, F., Disselhorst, M., Yin, J., Peikert, T., Udell, J., Johnson, S., Smadbeck, J., Murphy, S., McCune, A., Karagouga, G., Desai, A., Schaefer-Klein, J., Borad, M. J., Cheville, J., Vasmatzis, G., Baas, P. & Mansfield, A. S., Mar 2022, In: Journal of Thoracic Oncology. 17, 3, p. 446-454 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Validation and Characterization of FGFR2 Rearrangements in Cholangiocarcinoma with Comprehensive Genomic Profiling

Silverman, I. M., Li, M., Murugesan, K., Krook, M. A., Javle, M. M., Kelley, R. K., Borad, M. J., Roychowdhury, S., Meng, W., Yilmazel, B., Milbury, C., Shewale, S., Feliz, L., Burn, T. C. & Albacker, L. A., Apr 2022, In: Journal of Molecular Diagnostics. 24, 4, p. 351-364 14 p.

Research output: Contribution to journal › Article › peer-review

2021

Aspirin and statin use and the risk of gallbladder cancer

Prasai, K., Tella, S. H., Yadav, S., Kommalapati, A., Mara, K., Mady, M., Hassan, M. A., Wongjarupong, N., Rodriguez‐payan, N., Borad, M., Patel, T., Roberts, L. R. & Mahipal, A., Mar 1 2021, In: Cancers. 13, 5, p. 1-10 10 p., 1186.

Research output: Contribution to journal › Article › peer-review

Open Access

ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome

Baker, A. T., Boyd, R. J., Sarkar, D., Teijeira-Crespo, A., Chan, C. K., Bates, E., Waraich, K., Vant, J., Wilson, E., Truong, C. D., Lipka-Lloyd, M., Fromme, P., Vermaas, J., Williams, D., Machiesky, L. A., Heurich, M., Nagalo, B. M., Coughlan, L., Umlauf, S., Chiu, P. L., & 5 othersRizkallah, P. J., Cohen, T. S., Parker, A. L., Singharoy, A. & Borad, M. J., Dec 2021, In: Science Advances. 7, 49, eabl8213.

Research output: Contribution to journal › Article › peer-review

Circulating Tumor DNA-Based Testing and Actionable Findings in Patients with Advanced and Metastatic Pancreatic Adenocarcinoma

Botrus, G., Kosirorek, H., Sonbol, M. B., Kusne, Y., Uson Junior, P. L. S., Borad, M. J., Ahn, D. H., Kasi, P. M., Drusbosky, L. M., Dada, H., Surapaneni, P. K., Starr, J., Ritter, A., McMillan, J., Wylie, N., Mody, K. & Bekaii-Saab, T. S., Jul 2021, In: Oncologist. 26, 7, p. 569-578 10 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Clinical Impact of Pathogenic Germline Variants in Pancreatic Cancer: Results From a Multicenter, Prospective, Universal Genetic Testing Study

Uson, P. L. S., Samadder, N. J., Riegert-Johnson, D., Boardman, L., Borad, M. J., Ahn, D., Sonbol, M. B., Faigel, D. O., Fukami, N., Pannala, R., Kunze, K., Golafshar, M., Klint, M., Esplin, E. D., Nussbaum, R. L., Stewart, A. K. & Bekaii-Saab, T., Oct 8 2021, In: Clinical and translational gastroenterology. 12, 10, p. e00414

Research output: Contribution to journal › Article › peer-review

Open Access

Combination Immunotherapy for Hepatocellular Carcinoma: Where Are We Currently?

Uson Junior, P. L. S., Nagalo, B. M., Ahn, D. H., Bekaii-Saab, T. & Borad, M. J., May 1 2021, In: Seminars in liver disease. 41, 2, p. 136-141 6 p.

Research output: Contribution to journal › Article › peer-review

FGFR2 fusion proteins drive oncogenic transformation of mouse liver organoids towards cholangiocarcinoma

Cristinziano, G., Porru, M., Lamberti, D., Buglioni, S., Rollo, F., Amoreo, C. A., Manni, I., Giannarelli, D., Cristofoletti, C., Russo, G., Borad, M. J., Grazi, G. L., Diodoro, M. G., Giordano, S., Sacconi, A., Forcato, M., Anastasi, S., Leonetti, C. & Segatto, O., Aug 2021, In: Journal of hepatology. 75, 2, p. 351-362 12 p.

Research output: Contribution to journal › Article › peer-review

Final Overall Survival Efficacy Results of Ivosidenib for Patients with Advanced Cholangiocarcinoma with IDH1 Mutation: The Phase 3 Randomized Clinical ClarIDHy Trial

Zhu, A. X., Macarulla, T., Javle, M. M., Kelley, R. K., Lubner, S. J., Adeva, J., Cleary, J. M., Catenacci, D. V. T., Borad, M. J., Bridgewater, J. A., Harris, W. P., Murphy, A. G., Oh, D. Y., Whisenant, J. R., Lowery, M. A., Goyal, L., Shroff, R. T., El-Khoueiry, A. B., Chamberlain, C. X., Aguado-Fraile, E., & 7 othersChoe, S., Wu, B., Liu, H., Gliser, C., Pandya, S. S., Valle, J. W. & Abou-Alfa, G. K., Nov 2021, In: JAMA Oncology. 7, 11, p. 1669-1677 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Infigratinib (BGJ398) in previously treated patients with advanced or metastatic cholangiocarcinoma with FGFR2 fusions or rearrangements: mature results from a multicentre, open-label, single-arm, phase 2 study

Javle, M., Roychowdhury, S., Kelley, R. K., Sadeghi, S., Macarulla, T., Weiss, K. H., Waldschmidt, D. T., Goyal, L., Borbath, I., El-Khoueiry, A., Borad, M. J., Yong, W. P., Philip, P. A., Bitzer, M., Tanasanvimon, S., Li, A., Pande, A., Soifer, H. S., Shepherd, S. P., Moran, S., & 3 othersZhu, A. X., Bekaii-Saab, T. S. & Abou-Alfa, G. K., Oct 2021, In: The Lancet Gastroenterology and Hepatology. 6, 10, p. 803-815 13 p.

Research output: Contribution to journal › Article › peer-review

Inflation of tumor mutation burden by tumor-only sequencing in under-represented groups

Asmann, Y. W., Parikh, K., Bergsagel, P. L., Dong, H., Adjei, A. A., Borad, M. J. & Mansfield, A. S., Dec 2021, In: npj Precision Oncology. 5, 1, 22.

Research output: Contribution to journal › Article › peer-review

Open Access

Maintenance Therapy in First-Line Gastric and Gastroesophageal Junction Adenocarcinoma: A Retrospective Analysis

Walden, D., Sonbol, M. B., Buckner Petty, S., Yoon, H. H., Borad, M., Bekaii-Saab, T. S. & Ahn, D. H., Sep 10 2021, In: Frontiers in Oncology. 11, 641044.

Research output: Contribution to journal › Article › peer-review

Open Access

Oncogene Concatenated Enriched Amplicon Nanopore Sequencing for rapid, accurate, and affordable somatic mutation detection

Thirunavukarasu, D., Cheng, L. Y., Song, P., Chen, S. X., Borad, M. J., Kwong, L., James, P., Turner, D. J. & Zhang, D. Y., Dec 2021, In: Genome biology. 22, 1, 227.

Research output: Contribution to journal › Article › peer-review

Open Access

Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy

Kottke, T., Tonne, J., Evgin, L., Driscoll, C. B., van Vloten, J., Jennings, V. A., Huff, A. L., Zell, B., Thompson, J. M., Wongthida, P., Pulido, J., Schuelke, M. R., Samson, A., Selby, P., Ilett, E., McNiven, M., Roberts, L. R., Borad, M. J., Pandha, H., Harrington, K., & 2 othersMelcher, A. & Vile, R. G., Dec 1 2021, In: Nature communications. 12, 1, 1930.

Research output: Contribution to journal › Article › peer-review

Open Access

Pertuzumab and trastuzumab for HER2-positive, metastatic biliary tract cancer (MyPathway): a multicentre, open-label, phase 2a, multiple basket study

Javle, M., Borad, M. J., Azad, N. S., Kurzrock, R., Abou-Alfa, G. K., George, B., Hainsworth, J., Meric-Bernstam, F., Swanton, C., Sweeney, C. J., Friedman, C. F., Bose, R., Spigel, D. R., Wang, Y., Levy, J., Schulze, K., Cuchelkar, V., Patel, A. & Burris, H., Sep 2021, In: The Lancet Oncology. 22, 9, p. 1290-1300 11 p.

Research output: Contribution to journal › Article › peer-review

Phase IB study of sorafenib and evofosfamide in patients with advanced hepatocellular and renal cell carcinomas (NCCTG N1135, Alliance)

Tran, N. H., Foster, N. R., Mahipal, A., Byrne, T., Hubbard, J., Silva, A., Mody, K., Alberts, S. & Borad, M. J., Aug 2021, In: Investigational New Drugs. 39, 4, p. 1072-1080 9 p.

Research output: Contribution to journal › Article › peer-review

Safety, Efficacy, and Pharmacodynamics of Tremelimumab Plus Durvalumab for Patients With Unresectable Hepatocellular Carcinoma: Randomized Expansion of a Phase I/II Study

Kelley, R. K., Sangro, B., Harris, W., Ikeda, M., Okusaka, T., Kang, Y. K., Qin, S., Tai, D. W. M., Lim, H. Y., Yau, T., Yong, W. P., Cheng, A. L., Gasbarrini, A., Damian, S., Bruix, J., Borad, M., Bendell, J., Kim, T. Y., Standifer, N., He, P., & 4 othersMakowsky, M., Negro, A., Kudo, M. & Abou-Alfa, G. K., Sep 20 2021, In: Journal of Clinical Oncology. 39, 27, p. 2991-3001 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Strategies to develop potent oncolytic viruses and enhance their therapeutic efficacy

Moaven, O., Mangieri, C. W., Stauffer, J. A., Anastasiadis, P. Z. & Borad, M. J., 2021, In: JCO Precision Oncology. 5, p. 733-743 11 p.

Research output: Contribution to journal › Article › peer-review

2020

BL-8040, a CXCR4 antagonist, in combination with pembrolizumab and chemotherapy for pancreatic cancer: the COMBAT trial

Bockorny, B., Semenisty, V., Macarulla, T., Borazanci, E., Wolpin, B. M., Stemmer, S. M., Golan, T., Geva, R., Borad, M. J., Pedersen, K. S., Park, J. O., Ramirez, R. A., Abad, D. G., Feliu, J., Muñoz, A., Ponz-Sarvise, M., Peled, A., Lustig, T. M., Bohana-Kashtan, O., Shaw, S. M., & 6 othersSorani, E., Chaney, M., Kadosh, S., Vainstein Haras, A., Von Hoff, D. D. & Hidalgo, M., Jun 1 2020, In: Nature Medicine. 26, 6, p. 878-885 8 p.

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

Characteristics of Patients With Chronic Hepatitis B Virus Infection With Genotype E Predominance in Burkina Faso

Wongjarupong, N., Yonli, A. T., Nagalo, B. M., Djigma, F. W., Somda, S. K., Hassan, M. A., Mohamed, E. A., Sorgho, A. P., Compaore, T. R., Soubeiga, S. T., Kiendrebeogo, I., Sanou, M., Diarra, B., Yang, H. I., Chen, C. J., Ouattara, A. K., Zohoncon, T. M., Martinson, J. J., Buetow, K., Chamcheu, J. C., & 4 othersAntwi, S. O., Borad, M. J., Simpore, J. & Roberts, L. R., Dec 2020, In: Hepatology Communications. 4, 12, p. 1781-1792 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Evaluation of NUC-1031: a first-in-class ProTide in biliary tract cancer

Arora, M., Bogenberger, J. M., Abdelrahman, A., Leiting, J. L., Chen, X., Egan, J. B., Kasimsetty, A., Lenkiewicz, E., Malasi, S., Uson, P. L. S., Nagalo, B. M., Zhou, Y., Salomao, M. A., Kosiorek, H. E., Braggio, E., Barrett, M. T., Truty, M. J. & Borad, M. J., Jun 1 2020, In: Cancer chemotherapy and pharmacology. 85, 6, p. 1063-1078 16 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Genomic and epigenomic landscaping defines new therapeutic targets for adenosquamous carcinoma of the pancreas

Lenkiewicz, E., Malasi, S., Hogenson, T. L., Flores, L. F., Barham, W., Phillips, W. J., Roesler, A. S., Chambers, K. R., Rajbhandari, N., Hayashi, A., Antal, C. E., Downes, M., Grandgenett, P. M., Hollingsworth, M. A., Cridebring, D., Xiong, Y., Lee, J. H., Ye, Z., Yan, H., Hernandez, M. C., & 9 othersLeiting, J. L., Evans, R. M., Ordog, T., Truty, M. J., Borad, M. J., Reya, T., von Hoff, D. D., Fernandez-Zapico, M. E. & Barrett, M. T., Oct 15 2020, In: Cancer research. 80, 20, p. 4324-4334 11 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Genomic profiling reveals high frequency of DNA repair genetic aberrations in gallbladder cancer

Abdel-Wahab, R., Yap, T. A., Madison, R., Pant, S., Cooke, M., Wang, K., Zhao, H., Bekaii-Saab, T., Karatas, E., Kwong, L. N., Meric-Bernstam, F., Borad, M. & Javle, M., Dec 2020, In: Scientific reports. 10, 1, 22087.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Integration of Comprehensive Genomic Analysis and Functional Screening of Affected Molecular Pathways to Inform Cancer Therapy

Vasmatzis, G., Liu, M. C., Reganti, S., Feathers, R. W., Smadbeck, J., Johnson, S. H., Schaefer Klein, J. L., Harris, F. R., Yang, L., Kosari, F., Murphy, S. J., Borad, M. J., Thompson, E. A., Cheville, J. C. & Anastasiadis, P. Z., Feb 2020, In: Mayo Clinic proceedings. 95, 2, p. 306-318 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Ivosidenib in IDH1-mutant, chemotherapy-refractory cholangiocarcinoma (ClarIDHy): a multicentre, randomised, double-blind, placebo-controlled, phase 3 study

Abou-Alfa, G. K., Macarulla, T., Javle, M. M., Kelley, R. K., Lubner, S. J., Adeva, J., Cleary, J. M., Catenacci, D. V., Borad, M. J., Bridgewater, J., Harris, W. P., Murphy, A. G., Oh, D. Y., Whisenant, J., Lowery, M. A., Goyal, L., Shroff, R. T., El-Khoueiry, A. B., Fan, B., Wu, B., & 6 othersChamberlain, C. X., Jiang, L., Gliser, C., Pandya, S. S., Valle, J. W. & Zhu, A. X., Jun 2020, In: The Lancet Oncology. 21, 6, p. 796-807 12 p.

Research output: Contribution to journal › Article › peer-review

107 Scopus citations

Neutrophil to lymphocyte ratio as a prognostic marker in metastatic gallbladder cancer

Mady, M., Prasai, K., Tella, S. H., Yadav, S., Hallemeier, C. L., Rakshit, S., Roberts, L., Borad, M. & Mahipal, A., Oct 2020, In: HPB. 22, 10, p. 1490-1495 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Novel staging system using carbohydrate antigen (CA) 19-9 in extra-hepatic cholangiocarcinoma and its implications on overall survival: CA19-9 in the staging of extra-hepatic cholangiocarcinoma

Tella, S. H., Kommalapati, A., Yadav, S., Bergquist, J. R., Goyal, G., Durgin, L., Borad, M., Cleary, S. P., Truty, M. J. & Mahipal, A., May 2020, In: European Journal of Surgical Oncology. 46, 5, p. 789-795 7 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Oncolytic Virus with Attributes of Vesicular Stomatitis Virus and Measles Virus in Hepatobiliary and Pancreatic Cancers

Nagalo, B. M., Breton, C. A., Zhou, Y., Arora, M., Bogenberger, J. M., Barro, O., Steele, M. B., Jenks, N. J., Baker, A. T., Duda, D. G., Roberts, L. R., Russell, S. J., Peng, K. W. & Borad, M. J., Sep 25 2020, In: Molecular Therapy - Oncolytics. 18, p. 546-555 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Pemigatinib for previously treated, locally advanced or metastatic cholangiocarcinoma: a multicentre, open-label, phase 2 study

Abou-Alfa, G. K., Sahai, V., Hollebecque, A., Vaccaro, G., Melisi, D., Al-Rajabi, R., Paulson, A. S., Borad, M. J., Gallinson, D., Murphy, A. G., Oh, D. Y., Dotan, E., Catenacci, D. V., Van Cutsem, E., Ji, T., Lihou, C. F., Zhen, H., Féliz, L. & Vogel, A., May 2020, In: The Lancet Oncology. 21, 5, p. 671-684 14 p.

Research output: Contribution to journal › Article › peer-review

165 Scopus citations

Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours

Hong, D. S., Kang, Y. K., Borad, M., Sachdev, J., Ejadi, S., Lim, H. Y., Brenner, A. J., Park, K., Lee, J. L., Kim, T. Y., Shin, S., Becerra, C. R., Falchook, G., Stoudemire, J., Martin, D., Kelnar, K., Peltier, H., Bonato, V., Bader, A. G., Smith, S., & 3 othersKim, S., O’Neill, V. & Beg, M. S., May 26 2020, In: British journal of cancer. 122, 11, p. 1630-1637 8 p.

Research output: Contribution to journal › Article › peer-review

78 Scopus citations

Phase 1 trial of Vismodegib and Erlotinib combination in metastatic pancreatic cancer

McCleary-Wheeler, A. L., Carr, R. M., Palmer, S. R., Smyrk, T. C., Allred, J. B., Almada, L. L., Tolosa, E. J., Lamberti, M. J., Marks, D. L., Borad, M. J., Molina, J. R., Qi, Y., Lingle, W. L., Grothey, A., Pitot, H. C., Jatoi, A., Northfelt, D. W., Bryce, A. H., McWilliams, R. R., Okuno, S. H., & 10 othersHaluska, P., Kim, G. P., Colon-Otero, G., Lowe, V. J., Callstrom, M. R., Ma, W. W., Bekaii-Saab, T., Hung, M. C., Erlichman, C. & Fernandez-Zapico, M. E., Jan 2020, In: Pancreatology. 20, 1, p. 101-109 9 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Phase II Trial of Trifluridine/Tipiracil in Patients with Advanced, Refractory Biliary Tract Carcinoma

Chakrabarti, S., Zemla, T. J., Ahn, D. H., Ou, F. S., Fruth, B., Borad, M. J., Hartgers, M. L., Wessling, J., Walkes, R. L., Alberts, S. R., McWilliams, R. R., Liu, M. C., Durgin, L. M., Bekaii-Saab, T. S. & Mahipal, A., May 1 2020, In: Oncologist. 25, 5, p. 380-e763

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

SARS-CoV-2 and Plasmodium falciparum common immunodominant regions may explain low COVID-19 incidence in the malaria-endemic belt

Iesa, M. A. M., Osman, M. E. M., Hassan, M. A., Dirar, A. I. A., Abuzeid, N., Mancuso, J. J., Pandey, R., Mohammed, A. A., Borad, M. J., Babiker, H. M. & Konozy, E. H. E., Nov 2020, In: New Microbes and New Infections. 38, 100817.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Targeting of the Hedgehog/GLI and mTOR pathways in advanced pancreatic cancer, a phase 1 trial of Vismodegib and Sirolimus combination

Carr, R. M., Duma, N., McCleary-Wheeler, A. L., Almada, L. L., Marks, D. L., Graham, R. P., Smyrk, T. C., Lowe, V., Borad, M. J., Kim, G., Johnson, G. B., Allred, J. B., Yin, J., Lim, V. S., Bekaii-Saab, T., Ma, W. W., Erlichman, C., Adjei, A. A. & Fernandez-Zapico, M. E., Sep 2020, In: Pancreatology. 20, 6, p. 1115-1122 8 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Mitesh J Borad, MD

Research output

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