Michael John Ackerman, MD, PhD, FACC

  • 37897 Citations
  • 107 Scopus h-Index
1991 …2020

Research output per year

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Research Output

Outcomes of lead extraction without subsequent device reimplantation

Al-Hijji, M. A., Killu, A. M., Yousefian, O., Hodge, D. O., Park, J. Y., Hebsur, S., El Sabbagh, A., Pretorius, V. G., Ackerman, M. J., Friedman, P. A., Birgersdotter-Green, U. & Cha, Y-M., 2017, In : Europace. 19, 9, p. 1527-1534 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
48 Scopus citations

Pathogeneses of sudden cardiac death in national collegiate athletic association athletes

Harmon, K. G., Drezner, J. A., Maleszewski, J. J., Lopez-Anderson, M., Owens, D., Prutkin, J. M., Asif, I. M., Klossner, D. & Ackerman, M. J., Apr 2014, In : Circulation: Arrhythmia and Electrophysiology. 7, 2, p. 198-204 7 p.

Research output: Contribution to journalArticle

87 Scopus citations

Pathogenesis of unexplained drowning: New insights from a molecular autopsy

Tester, D. J., Kopplin, L. J., Creighton, W., Burke, A. P. & Ackerman, M. J., May 2005, In : Mayo Clinic proceedings. 80, 5, p. 596-600 5 p.

Research output: Contribution to journalArticle

64 Scopus citations

Pediatric-Onset Arrhythmogenic Cardiomyopathy: Look Right, Look Left, Look Both Ways

Ackerman, M. J. & Giudicessi, J. R., Jul 23 2019, In : Journal of the American College of Cardiology. 74, 3, p. 359-361 3 p.

Research output: Contribution to journalEditorial

Pediatric sudden cardiac arrest

Campbell, R., Berger, S., Ackerman, M. J., Morrow, W. R., Jenkins, K., Minich, L. L. A., Rosenthal, G. L., Snyder, C. S. & Twedell, J., Apr 2012, In : Pediatrics. 129, 4, p. e1094-e1102

Research output: Contribution to journalReview article

31 Scopus citations

Perioperative management of patients with congenital or acquired disorders of the QT interval

O'Hare, M., Maldonado, Y., Munro, J., Ackerman, M. J., Ramakrishna, H. & Sorajja, D., Apr 1 2018, In : British Journal of Anaesthesia. 120, 4, p. 629-644 16 p.

Research output: Contribution to journalReview article

5 Scopus citations

Personalized medicine: genetic diagnosis for inherited cardiomyopathies/channelopathies

Ackerman, M. J., Marcou, C. A. & Tester, D. J., Apr 1 2013, In : Revista Espanola de Cardiologia. 66, 4, p. 298-307 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Pharmacogenetic issues in thorough QT trials

Judson, R. S., Salisbury, B. A., Reed, C. R. & Ackerman, M. J., Jan 1 2006, In : Molecular Diagnosis and Therapy. 10, 3, p. 153-162 10 p.

Research output: Contribution to journalReview article

10 Scopus citations

Phenotype of Children with QT Prolongation Identified Using an Institution-Wide QT Alert System

Anderson, H. N., Bos, J. M., Haugaa, K. H., Morlan, B. W., Tarrell, R. F., Caraballo, P. & Ackerman, M. J., Oct 22 2015, In : Pediatric Cardiology. 36, 7, p. 1350-1356 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Phylogenetic and physicochemical analyses enhance the classification of rare nonsynonymous single nucleotide variants in type 1 and 2 long-QT syndrome

Giudicessi, J. R., Kapplinger, J. D., Tester, D. J., Alders, M., Salisbury, B. A., Wilde, A. A. M. & Ackerman, M. J., Oct 2012, In : Circulation: Cardiovascular Genetics. 5, 5, p. 519-528 10 p.

Research output: Contribution to journalArticle

45 Scopus citations

Physiological properties of hERG 1a/1b heteromeric currents and a hERG 1b-specific mutation associated with long-QT syndrome

Sale, H., Wang, J., O'Hara, T. J., Tester, D. J., Phartiyal, P., He, J. Q., Rudy, Y., Ackerman, M. J. & Robertson, G. A., Sep 26 2008, In : Circulation research. 103, 7, p. e81-e95

Research output: Contribution to journalArticle

85 Scopus citations

Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm

Cerrone, M., Montnach, J., Lin, X., Zhao, Y. T., Zhang, M., Agullo-Pascual, E., Leo-Macias, A., Alvarado, F. J., Dolgalev, I., Karathanos, T. V., Malkani, K., Van Opbergen, C. J. M., Van Bavel, J. J. A., Yang, H. Q., Vasquez, C., Tester, D., Fowler, S., Liang, F., Rothenberg, E., Heguy, A. & 7 others, Morley, G. E., Coetzee, W. A., Trayanova, N. A., Ackerman, M. J., Van Veen, T. A. B., Valdivia, H. H. & Delmar, M., Dec 1 2017, In : Nature communications. 8, 1, 106.

Research output: Contribution to journalArticle

47 Scopus citations

Plakophilin-2 Truncation Variants in Patients Clinically Diagnosed With Catecholaminergic Polymorphic Ventricular Tachycardia and Decedents With Exercise-Associated Autopsy Negative Sudden Unexplained Death in the Young

Tester, D. J., Ackerman, J. P., Giudicessi, J. R., Ackerman, N. C., Cerrone, M., Delmar, M. & Ackerman, M. J., Jan 2019, In : JACC: Clinical Electrophysiology. 5, 1, p. 120-127 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Platelet Function Analyzer 100 and Brain Natriuretic Peptide as Biomarkers in Obstructive Hypertrophic Cardiomyopathy

Blackshear, J. L., Safford, R. E., Thomas, C. S., Bos, J. M., Ackerman, M. J., Geske, J. B., Ommen, S. R., Shapiro, B. P. & Johns, G. S., Mar 15 2018, In : American Journal of Cardiology. 121, 6, p. 768-774 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

PLN-encoded phospholamban mutation in a large cohort of hypertrophic cardiomyopathy cases: Summary of the literature and implications for genetic testing

Landstrom, A. P., Adekola, B. A., Bos, J. M., Ommen, S. R. & Ackerman, M. J., Jan 2011, In : American heart journal. 161, 1, p. 165-171 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

Population-based study of QT interval prolongation in patients with rheumatoid arthritis

Chauhan, K., Ackerman, M. J., Crowson, C., Matteson, E. L. & Gabriel, S. E., 2015, In : Clinical and Experimental Rheumatology. 33, 1, p. 84-89 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Post hoc Analysis for Detecting Individual Rare Variant Risk Associations Using Probit Regression Bayesian Variable Selection Methods in Case-Control Sequencing Studies

Larson, N. B., McDonnell, S., Albright, L. C., Teerlink, C., Stanford, J., Ostrander, E. A., Isaacs, W. B., Xu, J., Cooney, K. A., Lange, E., Schleutker, J., Carpten, J. D., Powell, I., Bailey-Wilson, J., Cussenot, O., Cancel-Tassin, G., Giles, G., MacInnis, R., Maier, C., Whittemore, A. S. & 12 others, Hsieh, C. L., Wiklund, F., Catolona, W. J., Foulkes, W., Mandal, D., Eeles, R., Kote-Jarai, Z., Ackerman, M. J., Olson, T. M., Klein, C. J., Thibodeau, S. N. & Schaid, D. J., Sep 1 2016, In : Genetic epidemiology. 40, 6, p. 461-469 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Post-Mortem Cardiovascular Implantable Electronic Device Interrogation: Clinical Indications and Potential Benefits

Ackerman, M. J. & Giudicessi, J. R., Sep 20 2016, In : Journal of the American College of Cardiology. 68, 12, p. 1265-1267 3 p.

Research output: Contribution to journalEditorial

1 Scopus citations
70 Scopus citations

Postmortem Long QT Syndrome Genetic Testing for Sudden Unexplained Death in the Young

Tester, D. J. & Ackerman, M. J., Jan 16 2007, In : Journal of the American College of Cardiology. 49, 2, p. 240-246 7 p.

Research output: Contribution to journalArticle

287 Scopus citations

Postmortem molecular analysis of SCN5A defects in sudden infant death syndrome

Ackerman, M. J., Siu, B. L., Sturner, W. Q., Tester, D. J., Valdivia, C. R., Makielski, J. C. & Towbin, J. A., Nov 14 2001, In : Journal of the American Medical Association. 286, 18, p. 2264-2269 6 p.

Research output: Contribution to journalArticle

Open Access
382 Scopus citations

Post-mortem Whole Exome Sequencing with Gene-Specific Analysis for Autopsy-Negative Sudden Unexplained Death in the Young: A Case Series

Narula, N., Tester, D. J., Paulmichl, A., Maleszewski, J. J. & Ackerman, M. J., Mar 19 2015, In : Pediatric Cardiology. 36, 4, p. 768-778 11 p.

Research output: Contribution to journalArticle

42 Scopus citations

Potassium-channel mutations and cardiac arrhythmias - Diagnosis and therapy

Giudicessi, J. R. & Ackerman, M. J., Jun 2012, In : Nature Reviews Cardiology. 9, 6, p. 319-332 14 p.

Research output: Contribution to journalReview article

58 Scopus citations

Potential depot medroxyprogesterone acetate-triggered torsades de pointes in a case of congenital type 2 long QT syndrome

Giudicessi, J. R., Brost, B. C., Traynor, K. D. & Ackerman, M. J., Jul 2012, In : Heart rhythm. 9, 7, p. 1143-1147 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Potentially modifiable factors of dofetilide-associated risk of torsades de pointes among hospitalized patients with atrial fibrillation

Naksuk, N., Sugrue, A. M., Padmanabhan, D., Kella, D., DeSimone, C. V., Kapa, S., Asirvatham, S. J., Lee, H. C., Ackerman, M. J. & Noseworthy, P., Jan 1 2018, (Accepted/In press) In : Journal of Interventional Cardiac Electrophysiology.

Research output: Contribution to journalArticle

3 Scopus citations

Precision Cardiovascular Medicine: State of Genetic Testing

Giudicessi, J. R., Kullo, I. J. & Ackerman, M. J., Apr 1 2017, In : Mayo Clinic proceedings. 92, 4, p. 642-662 21 p.

Research output: Contribution to journalReview article

23 Scopus citations

Prenatal molecular genetic diagnosis of congenital long QT syndrome by strategic genotyping

Tester, D. J., McCormack, J. & Ackerman, M. J., Mar 15 2004, In : American Journal of Cardiology. 93, 6, p. 788-791 4 p.

Research output: Contribution to journalArticle

20 Scopus citations

Prevalence, clinical significance, and natural history of left ventricular apical aneurysms in hypertrophic cardiomyopathy

Maron, M. S., Finley, J. J., Bos, J. M., Hauser, T. H., Manning, W. J., Haas, T. S., Lesser, J. R., Udelson, J. E., Ackerman, M. J. & Maron, B. J., Oct 7 2008, In : Circulation. 118, 15, p. 1541-1549 9 p.

Research output: Contribution to journalArticle

306 Scopus citations

Prevalence and age-dependence of malignant mutations in the beta-myosin heavy chain and troponin T genes in hypertrophic cardiomyopathy: A comprehensive outpatient perspective

Ackerman, M. J., VanDriest, S. L., Ommen, S. R., Will, M. L., Nishimura, R. A., Tajik, A. J. & Gersh, B. J., Jun 19 2002, In : Journal of the American College of Cardiology. 39, 12, p. 2042-2048 7 p.

Research output: Contribution to journalArticle

200 Scopus citations

Prevalence and clinical correlates of QT prolongation in patients with hypertrophic cardiomyopathy

Johnson, J. N., Grifoni, C., Bos, J. M., Saber-Ayad, M., Ommen, S. R., Nistri, S., Cecchi, F., Olivotto, I. & Ackerman, M. J., May 2011, In : European heart journal. 32, 9, p. 1114-1120 7 p.

Research output: Contribution to journalArticle

58 Scopus citations

Prevalence and clinical phenotype of concomitant long QT syndrome and arrhythmogenic bileaflet mitral valve prolapse

Giudicessi, J. R., Rohatgi, R. K., Bos, J. M. & Ackerman, M. J., Jan 1 2018, (Accepted/In press) In : International Journal of Cardiology.

Research output: Contribution to journalArticle

2 Scopus citations

Prevalence and electrophysiological phenotype of rare SCN5A genetic variants identified in unexplained sudden cardiac arrest survivors

Giudicessi, J. R., Ye, D., Stutzman, M. J., Zhou, W., Tester, D. J. & Ackerman, M. J., Apr 1 2020, In : Europace. 22, 4, p. 622-631 10 p.

Research output: Contribution to journalArticle

Prevalence and Outcome of High-Risk QT Prolongation Recorded in the Emergency Department from an Institution-Wide QT Alert System

Anderson, H. N., Bos, J. M., Haugaa, K. H., Morlan, B. W., Tarrell, R. F., Caraballo, P. & Ackerman, M. J., 2017, (Accepted/In press) In : Journal of Emergency Medicine.

Research output: Contribution to journalArticle

9 Scopus citations
33 Scopus citations

Prevalence and severity of "benign" mutations in the β-myosin heavy chain, cardiac troponin T, and α-tropomyosin genes in hypertrophic cardiomyopathy

Van Driest, S. L., Ackerman, M. J., Ommen, S. R., Shakur, R., Will, M. L., Nishimura, R. A., Tajik, A. J. & Gersh, B. J., Dec 10 2002, In : Circulation. 106, 24, p. 3085-3090 6 p.

Research output: Contribution to journalArticle

151 Scopus citations

Prevalence and spectrum of electroencephalogram-identified epileptiform activity among patients with long QT syndrome

Anderson, J. H., Bos, J. M., Cascino, G. D. & Ackerman, M. J., Jan 1 2014, In : Heart rhythm. 11, 1, p. 53-57 5 p.

Research output: Contribution to journalArticle

41 Scopus citations

Prevalence and spectrum of large deletions or duplications in the major long QT syndrome-susceptibility genes and implications for long QT syndrome genetic testing

Tester, D. J., Benton, A. J., Train, L., Deal, B., Baudhuin, L. M. & Ackerman, M. J., Oct 15 2010, In : American Journal of Cardiology. 106, 8, p. 1124-1128 5 p.

Research output: Contribution to journalArticle

48 Scopus citations

Prevalence and spectrum of thin filament mutations in an outpatient referral population with hypertrophic cardiomyopathy

Van Driest, S. L., Ellsworth, E. G., Ommen, S. R., Tajik, A. J., Gersh, B. J. & Ackerman, M. J., Jul 29 2003, In : Circulation. 108, 4, p. 445-451 7 p.

Research output: Contribution to journalArticle

171 Scopus citations

Prevalence of early-onset atrial fibrillation in congenital long QT syndrome

Johnson, J. N., Tester, D. J., Perry, J., Salisbury, B. A., Reed, C. R. & Ackerman, M. J., May 2008, In : Heart rhythm. 5, 5, p. 704-709 6 p.

Research output: Contribution to journalArticle

117 Scopus citations

Prevention of sudden cardiac death with implantable cardioverter- defibrillators in children and adolescents with hypertrophic cardiomyopathy

Maron, B. J., Spirito, P., Ackerman, M. J., Casey, S. A., Semsarian, C., Estes, N. A. M., Shannon, K. M., Ashley, E. A., Day, S. M., Pacileo, G., Formisano, F., Devoto, E., Anastasakis, A., Bos, J. M., Woo, A., Autore, C., Pass, R. H., Boriani, G., Garberich, R. F., Almquist, A. K. & 5 others, Russell, M. W., Boni, L., Berger, S., Maron, M. S. & Link, M. S., Apr 9 2013, In : Journal of the American College of Cardiology. 61, 14, p. 1527-1535 9 p.

Research output: Contribution to journalArticle

150 Scopus citations

Prevention of torsade de pointes in hospital settings: A scientific statement from the American heart association and the American college of cardiology foundation

Drew, B. J., Ackerman, M. J., Funk, M., Gibler, W. B., Kligfield, P., Menon, V., Philippides, G. J., Roden, D. M. & Zareba, W., Mar 2010, In : Circulation. 121, 8, p. 1047-1060 14 p.

Research output: Contribution to journalReview article

295 Scopus citations
186 Scopus citations

Primer on medical genomics part VI: Genomics and molecular genetics in clinical practice

Ansell, S. M., Ackerman, M. J., Black, J. L., Roberts, L. R. & Tefferi, A., Mar 1 2003, In : Mayo Clinic proceedings. 78, 3, p. 307-317 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Primer on medical genomics part VIII: Essentials of medical genetics for the practicing physician

Ensenauer, R. E., Reinke, S. S., Ackerman, M. J., Tester, D. J., Whiteman, D. A. H. & Tefferi, A., Jul 1 2003, In : Mayo Clinic proceedings. 78, 7, p. 846-857 12 p.

Research output: Contribution to journalReview article

14 Scopus citations

Prognostic implications of mutation-specific QTc standard deviation in congenital long QT syndrome

Mathias, A., Moss, A. J., Lopes, C. M., Barsheshet, A., McNitt, S., Zareba, W., Robinson, J. L., Locati, E. H., Ackerman, M. J., Benhorin, J., Kaufman, E. S., Platonov, P. G., Qi, M., Shimizu, W., Towbin, J. A., Michael Vincent, G., Wilde, A. A. M., Zhang, L. & Goldenberg, I., May 1 2013, In : Heart rhythm. 10, 5, p. 720-725 6 p.

Research output: Contribution to journalArticle

15 Scopus citations
3 Scopus citations

Promoting arrhythmia susceptibility

Bunch, T. J. & Ackerman, M. J., Jan 1 2006, In : Circulation. 113, 3, p. 330-332 3 p.

Research output: Contribution to journalEditorial

4 Scopus citations

Properties of WT and mutant hERG K+ channels expressed in neonatal mouse cardiomyocytes

Lin, E. C., Holzem, K. M., Anson, B. D., Moungey, B. M., Balijepalli, S. Y., Tester, D. J., Ackerman, M. J., Delisle, B. P., Balijepalli, R. C. & January, C. T., Jun 2010, In : American Journal of Physiology - Heart and Circulatory Physiology. 298, 6, p. H1842-H1849

Research output: Contribution to journalArticle

13 Scopus citations