Michael John Ackerman, MD, PhD, FACC

  • 34717 Citations
  • 103 Scopus h-Index
1991 …2020
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1991 2019

2012
38 Citations (Scopus)

Novel Mutations in the KCND3-Encoded Kv4.3 K+ Channel Associated with Autopsy-Negative Sudden Unexplained Death

Giudicessi, J. R., Ye, D., Kritzberger, C. J., Nesterenko, V. V., Tester, D. J., Antzelevitch, C. & Ackerman, M. J., Jun 2012, In : Human Mutation. 33, 6, p. 989-997 9 p.

Research output: Contribution to journalArticle

Sudden Infant Death
Sudden Death
Autopsy
Mutation
Brugada Syndrome
29 Citations (Scopus)

Pediatric sudden cardiac arrest

Campbell, R., Berger, S., Ackerman, M. J., Morrow, W. R., Jenkins, K., Minich, L. L., Rosenthal, G. L., Snyder, C. S. & Twedell, J., Apr 2012, In : Pediatrics. 129, 4

Research output: Contribution to journalArticle

Sudden Cardiac Death
Pediatrics
Brugada Syndrome
Community Health Services
Sudden Infant Death
44 Citations (Scopus)

Phylogenetic and physicochemical analyses enhance the classification of rare nonsynonymous single nucleotide variants in type 1 and 2 long-QT syndrome

Giudicessi, J. R., Kapplinger, J. D., Tester, D. J., Alders, M., Salisbury, B. A., Wilde, A. A. M. & Ackerman, M. J., Oct 2012, In : Circulation: Cardiovascular Genetics. 5, 5, p. 519-528 10 p.

Research output: Contribution to journalArticle

Romano-Ward Syndrome
Nucleotides
Long QT Syndrome
Cyclic Nucleotides
Computer Simulation
58 Citations (Scopus)

Potassium-channel mutations and cardiac arrhythmias - Diagnosis and therapy

Giudicessi, J. R. & Ackerman, M. J., Jun 2012, In : Nature Reviews Cardiology. 9, 6, p. 319-332 14 p.

Research output: Contribution to journalArticle

Potassium Channels
Action Potentials
Cardiac Arrhythmias
Mutation
Brugada Syndrome
4 Citations (Scopus)

Potential depot medroxyprogesterone acetate-triggered torsades de pointes in a case of congenital type 2 long QT syndrome

Giudicessi, J. R., Brost, B. C., Traynor, K. D. & Ackerman, M. J., Jul 2012, In : Heart Rhythm. 9, 7, p. 1143-1147 5 p.

Research output: Contribution to journalArticle

Cardiovascular Pregnancy Complications
Hypodermoclysis
Female Contraceptive Agents
Heart Conduction System
Prosthesis Failure
49 Citations (Scopus)

Ranolazine decreases mechanosensitivity of the voltage-gated sodium ion channel NaV1.5: A novel mechanism of drug action

Beyder, A., Strege, P. R., Reyes, S., Bernard, C. E., Terzic, A., Makielski, J., Ackerman, M. J. & Farrugia, G., Jun 5 2012, In : Circulation. 125, 22, p. 2698-2706 9 p.

Research output: Contribution to journalArticle

Voltage-Gated Sodium Channels
Sodium Channels
Pharmaceutical Preparations
Pressure
Lidocaine
15 Citations (Scopus)

Ranolazine inhibits shear sensitivity of endogenous Na+ current and spontaneous action potentials in HL-1 cells

Strege, P., Beyder, A., Bernard, C., Crespo-Diaz, R., Behfar, A., Terzic, A., Ackerman, M. J. & Farrugia, G., Nov 2012, In : Channels. 6, 6, p. 457-462 6 p.

Research output: Contribution to journalArticle

Action Potentials
Shear stress
Cardiac Myocytes
Baths
Cells
10 Citations (Scopus)

Repeat long QT syndrome genetic testing of phenotype-positive cases: Prevalence and etiology of detection misses

Medlock, M. M., Tester, D. J., Will, M. L., Bos, J. M. & Ackerman, M. J., Dec 2012, In : Heart Rhythm. 9, 12, p. 1977-1982 6 p.

Research output: Contribution to journalArticle

Long QT Syndrome
Genetic Testing
High Pressure Liquid Chromatography
Phenotype
Mutation
14 Citations (Scopus)

Restricting sports for athletes with heart disease: Are we saving lives, avoiding lawsuits, or just promoting obesity and sedentary living?

Vaseghi, M., Ackerman, M. J. & Mandapati, R., Mar 2012, In : Pediatric Cardiology. 33, 3, p. 407-416 10 p.

Research output: Contribution to journalArticle

Athletes
Sports
Heart Diseases
Obesity
Cardiac Arrhythmias
128 Citations (Scopus)

Spectrum and prevalence of mutations involving BrS1- Through BrS12-susceptibility genes in a cohort of unrelated patients referred for brugada syndrome genetic testing: Implications for genetic testing

Crotti, L., Marcou, C. A., Tester, D. J., Castelletti, S., Giudicessi, J. R., Torchio, M., Medeiros-Domingo, A., Simone, S., Will, M. L., Dagradi, F., Schwartz, P. J. & Ackerman, M. J., Oct 9 2012, In : Journal of the American College of Cardiology. 60, 15, p. 1410-1418 9 p.

Research output: Contribution to journalArticle

Brugada Syndrome
Genetic Testing
Mutation
Genes
Calcium Channels
2 Citations (Scopus)

Surprise, surprise: Idiopathic, isolated complete atrioventricular block may be heritable

Cannon, B. C. & Ackerman, M. J., Sep 18 2012, In : Circulation. 126, 12, p. 1434-1435 2 p.

Research output: Contribution to journalArticle

NAV1.5 Voltage-Gated Sodium Channel
Mass Screening
Atrioventricular Block
Electrocardiography
Pregnancy
14 Citations (Scopus)

TGFβ-inducible early gene-1 (TIEG1) mutations in hypertrophic cardiomyopathy

Bos, J. M., Subramaniam, M., Hawse, J. R., Christiaans, I., Rajamannan, N. M., Maleszewski, J., Edwards, W. D., Wilde, A. A. M., Spelsberg, T. C. & Ackerman, M. J., Jun 2012, In : Journal of Cellular Biochemistry. 113, 6, p. 1896-1903 8 p.

Research output: Contribution to journalArticle

Hypertrophic Cardiomyopathy
Genes
Mutation
Heart Diseases
Up-Regulation
62 Citations (Scopus)

The molecular autopsy: Should the evaluation continue after the funeral?

Tester, D. J. & Ackerman, M. J., Mar 2012, In : Pediatric Cardiology. 33, 3, p. 461-470 10 p.

Research output: Contribution to journalArticle

Sudden Death
Autopsy
Sudden Cardiac Death
Channelopathies
Brugada Syndrome
19 Citations (Scopus)

The molecular autopsy: An indispensable step following sudden cardiac death in the young?

Boczek, N. J., Tester, D. J. & Ackerman, M. J., Sep 2012, In : Herzschrittmachertherapie und Elektrophysiologie. 23, 3, p. 167-173 7 p.

Research output: Contribution to journalArticle

Sudden Cardiac Death
Sudden Death
Autopsy
Channelopathies
Brugada Syndrome
29 Citations (Scopus)

Trigger-specific ion-channel mechanisms, risk factors, and response to therapy in type 1 long QT syndrome

Goldenberg, I., Thottathil, P., Lopes, C. M., Moss, A. J., McNitt, S., Jin, O. U., Robinson, J. L., Zareba, W., Ackerman, M. J., Kaufman, E. S., Towbin, J. A., Vincent, M. & Barsheshet, A., Jan 2012, In : Heart Rhythm. 9, 1, p. 49-56 8 p.

Research output: Contribution to journalArticle

Romano-Ward Syndrome
Ion Channels
Arousal
Sleep
Exercise
569 Citations (Scopus)

Truncations of titin causing dilated cardiomyopathy

Herman, D. S., Lam, L., Taylor, M. R. G., Wang, L., Teekakirikul, P., Christodoulou, D., Conner, L., DePalma, S. R., McDonough, B., Sparks, E., Teodorescu, D. L., Cirino, A. L., Banner, N. R., Pennell, D. J., Graw, S., Merlo, M., Di Lenarda, A., Sinagra, G., Bos, J. M., Ackerman, M. J. & 9 others, Mitchell, R. N., Murry, C. E., Lakdawala, N. K., Ho, C. Y., Barton, P. J. R., Cook, S. A., Mestroni, L., Seidman, J. G. & Seidman, C. E., Feb 16 2012, In : New England Journal of Medicine. 366, 7, p. 619-628 10 p.

Research output: Contribution to journalArticle

Connectin
Dilated Cardiomyopathy
Mutation
Hypertrophic Cardiomyopathy
Lod Score
97 Citations (Scopus)

Variants in the 3′ untranslated region of the KCNQ1-encoded K v7.1 potassium channel modify disease severity in patients with type 1 long QT syndrome in an allele-specific manner

Amin, A. S., Giudicessi, J. R., Tijsen, A. J., Spanjaart, A. M., Reckman, Y. J., Klemens, C. A., Tanck, M. W., Kapplinger, J. D., Hofman, N., Sinner, M. F., Mller, M., Wijnen, W. J., Tan, H. L., Bezzina, C. R., Creemers, E. E., Wilde, A. A. M., Ackerman, M. J. & Pinto, Y. M., Mar 2012, In : European Heart Journal. 33, 6, p. 714-723 10 p.

Research output: Contribution to journalArticle

Romano-Ward Syndrome
Potassium Channels
3' Untranslated Regions
Single Nucleotide Polymorphism
Alleles
2011
36 Citations (Scopus)

Anesthetic management of patients with Brugada syndrome: A case series and literature review

Kloesel, B., Ackerman, M. J., Sprung, J., Narr, B. J. & Weingarten, T. N., Sep 2011, In : Canadian Journal of Anesthesia. 58, 9, p. 824-836 13 p.

Research output: Contribution to journalArticle

Brugada Syndrome
Anesthetics
Anesthesia
Propofol
Hyperkalemia
3 Citations (Scopus)

Clinical spectrum in a family with tropomyosin-mediated hypertrophic cardiomyopathy and sudden death in childhood

Makhoul, M., Ackerman, M. J., Atkins, D. L. & Law, I. H., Feb 2011, In : Pediatric Cardiology. 32, 2, p. 215-220 6 p.

Research output: Contribution to journalArticle

Tropomyosin
Hypertrophic Cardiomyopathy
Sudden Death
Hypertrophy
Shock
146 Citations (Scopus)

Disrupted junctional membrane complexes and hyperactive ryanodine receptors after acute junctophilin knockdown in mice

Van Oort, R. J., Garbino, A., Wang, W., Dixit, S. S., Landstrom, A. P., Gaur, N., De Almeida, A. C., Skapura, D. G., Rudy, Y., Burns, A. R., Ackerman, M. J. & Wehrens, X. H. T., Mar 8 2011, In : Circulation. 123, 9, p. 979-988 10 p.

Research output: Contribution to journalArticle

Ryanodine Receptor Calcium Release Channel
Membranes
Excitation Contraction Coupling
Sarcoplasmic Reticulum
junctophilin
190 Citations (Scopus)

Distinguishing arrhythmogenic right ventricular cardiomyopathy/dysplasia- associated mutations from background genetic noise

Kapplinger, J. D., Landstrom, A. P., Salisbury, B. A., Callis, T. E., Pollevick, G. D., Tester, D. J., Cox, M. G. P. J., Bhuiyan, Z., Bikker, H., Wiesfeld, A. C. P., Hauer, R. N. W., Van Tintelen, J. P., Jongbloed, J. D. H., Calkins, H., Judge, D. P., Wilde, A. A. M. & Ackerman, M. J., Jun 7 2011, In : Journal of the American College of Cardiology. 57, 23, p. 2317-2327 11 p.

Research output: Contribution to journalArticle

Arrhythmogenic Right Ventricular Dysplasia
Noise
Mutation
Missense Mutation
Genetic Background
53 Citations (Scopus)

Dysferlin, annexin A1, and mitsugumin 53 are upregulated in muscular dystrophy and localize to longitudinal tubules of the T-system with stretch

Waddell, L. B., Lemckert, F. A., Zheng, X. F., Tran, J., Evesson, F. J., Hawkes, J. M., Lek, A., Street, N. E., Lin, P., Clarke, N. F., Landstrom, A. P., Ackerman, M. J., Weisleder, N., Ma, J., North, K. N. & Cooper, S. T., Apr 2011, In : Journal of Neuropathology and Experimental Neurology. 70, 4, p. 302-313 12 p.

Research output: Contribution to journalArticle

Annexin A1
Muscular Dystrophies
Caveolin 3
Membranes
Muscles
54 Citations (Scopus)

Electrocardiographic and oximetric changes during partial complex and generalized seizures

Moseley, B. D., Wirrell, E. C., Nickels, K. C., Johnson, J. N., Ackerman, M. J. & Britton, J., Aug 2011, In : Epilepsy Research. 95, 3, p. 237-245 9 p.

Research output: Contribution to journalArticle

Seizures
Stroke
Sudden Death
Epilepsy
Sinus Tachycardia
32 Citations (Scopus)

Electrocardiographic changes and arrhythmias following percutaneous atrial septal defect and patent foramen ovale device closure

Johnson, J. N., Marquardt, M. L., Ackerman, M. J., Asirvatham, S. J., Reeder, G. S., Cabalka, A. K., Cetta, F. & Hagler, D. J., Aug 1 2011, In : Catheterization and Cardiovascular Interventions. 78, 2, p. 254-261 8 p.

Research output: Contribution to journalArticle

Patent Foramen Ovale
Atrial Heart Septal Defects
Cardiac Arrhythmias
Equipment and Supplies
Electrocardiography
138 Citations (Scopus)

Genetic testing for potentially lethal, highly treatable inherited cardiomyopathies/channelopathies in clinical practice

Tester, D. J. & Ackerman, M. J., Mar 8 2011, In : Circulation. 123, 9, p. 1021-1037 17 p.

Research output: Contribution to journalArticle

Channelopathies
Long QT Syndrome
Genetic Testing
Cardiomyopathies
Ion Channels
15 Citations (Scopus)

Genotype-specific QT correction for heart rate and the risk of life-threatening cardiac events in adolescents with congenital long-QT syndrome

Barsheshet, A., Peterson, D. R., Moss, A. J., Schwartz, P. J., Kaufman, E. S., McNitt, S., Polonsky, S., Buber, J., Zareba, W., Robinson, J. L., Ackerman, M. J., Benhorin, J., Towbin, J. A., Vincent, G. M., Zhang, L. & Goldenberg, I., Aug 2011, In : Heart Rhythm. 8, 8, p. 1207-1213 7 p.

Research output: Contribution to journalArticle

Long QT Syndrome
Heart Rate
Genotype
Romano-Ward Syndrome
Inborn Genetic Diseases
17 Citations (Scopus)

Holter monitoring in the evaluation of congenital long QT syndrome

Mauriello, D. A., Johnson, J. N. & Ackerman, M. J., Sep 2011, In : PACE - Pacing and Clinical Electrophysiology. 34, 9, p. 1100-1104 5 p.

Research output: Contribution to journalArticle

Long QT Syndrome
Ambulatory Electrocardiography
Channelopathies
Supraventricular Tachycardia
Ventricular Premature Complexes
583 Citations (Scopus)

HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies: This document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA)

Ackerman, M. J., Priori, S. G., Willems, S., Berul, C., Brugada, R., Calkins, H., Camm, A. J., Ellinor, P. T., Gollob, M., Hamilton, R., Hershberger, R. E., Judge, D. P., Le Marec, H., McKenna, W. J., Schulze-Bahr, E., Semsarian, C., Towbin, J. A., Watkins, H., Wilde, A., Wolpert, C. & 1 others, Zipes, D. P., Aug 2011, In : Heart Rhythm. 8, 8, p. 1308-1339 32 p.

Research output: Contribution to journalArticle

Restrictive Cardiomyopathy
Channelopathies
Brugada Syndrome
Hypertrophic Cardiomyopathy
Genetic Counseling
419 Citations (Scopus)

HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies

Ackerman, M. J., Priori, S. G., Willems, S., Berul, C., Brugada, R., Calkins, H., Camm, A. J., Ellinor, P. T., Gollob, M., Hamilton, R., Hershberger, R. E., Judge, D. P., Le Marec, H., McKenna, W. J., Schulze-Bahr, E., Semsarian, C., Towbin, J. A., Watkins, H., Wilde, A., Wolpert, C. & 2 others, Zipes, D. P. & Olson, S., Aug 2011, In : Europace. 13, 8, p. 1077-1109 33 p.

Research output: Contribution to journalArticle

Channelopathies
Medical Societies
Genetic Testing
Cardiomyopathies
8 Citations (Scopus)

HRS policy statement: Clinical cardiac electrophysiology fellowship curriculum: Update 2011

Link, M. S., Exner, D. V., Anderson, M., Ackerman, M. J., Al-Ahmad, A., Knight, B. P., Markowitz, S. M., Kaufman, E. S., Haines, D., Asirvatham, S. J., Callans, D. J., Mounsey, J. P., Bogun, F., Narayan, S. M., Krahn, A. D., Mittal, S., Singh, J., Fisher, J. D. & Chugh, S. S., Aug 2011, In : Heart Rhythm. 8, 8, p. 1340-1356 17 p.

Research output: Contribution to journalArticle

Artificial Cardiac Pacing
Cardiac Electrophysiology
Cardiac Electrophysiologic Techniques
Sudden Cardiac Death
Curriculum
60 Citations (Scopus)

Junctophilin-2 expression silencing causes cardiocyte hypertrophy and abnormal intracellular calcium-handling

Landstrom, A. P., Kellen, C. A., Dixit, S. S., Van Oort, R. J., Garbino, A., Weisleder, N., Ma, J., Wehrens, X. H. T. & Ackerman, M. J., Mar 2011, In : Circulation: Heart Failure. 4, 2, p. 214-223 10 p.

Research output: Contribution to journalArticle

Hypertrophy
Calcium
Hypertrophic Cardiomyopathy
Cardiomegaly
junctophilin
8 Citations (Scopus)

Left cardiac sympathetic denervation in a pediatric patient with hypertrophic cardiomyopathy and recurrent ventricular fibrillation

Johnson, J. N., Harris, K. M., Moir, C., Lau, Y. R. & Ackerman, M. J., Oct 2011, In : Heart Rhythm. 8, 10, p. 1591-1594 4 p.

Research output: Contribution to journalArticle

Heart Conduction System
Video-Assisted Thoracic Surgery
Sympathectomy
Hypertrophic Cardiomyopathy
Ventricular Fibrillation
2 Citations (Scopus)

Left ventricular noncompaction syndrome masquerading or misdiagnosed as congenital long QT syndrome: Remember QT prolongation does not equal long QT syndrome

Coleman, M. A., Bos, J. M., Phillips, S. D., Souza, J. J. & Ackerman, M. J., Sep 2011, In : Congenital Heart Disease. 6, 5, p. 492-498 7 p.

Research output: Contribution to journalArticle

Long QT Syndrome
Diagnostic Errors
Sympathectomy
Ventricular Fibrillation
Therapeutics
47 Citations (Scopus)

Loss-of-function mutations in the KCNJ8-Encoded Kir6.1 KATP channel and sudden infant death syndrome

Tester, D. J., Tan, B. H., Medeiros-Domingo, A., Song, C., Makielski, J. C. & Ackerman, M. J., Oct 2011, In : Circulation: Cardiovascular Genetics. 4, 5, p. 510-515 6 p.

Research output: Contribution to journalArticle

KATP Channels
Sudden Infant Death
Mutation
Pinacidil
Channelopathies
82 Citations (Scopus)

Microvascular function is selectively impaired in patients with hypertrophic cardiomyopathy and sarcomere myofilament gene mutations

Olivotto, I., Girolami, F., Sciagr, R., Ackerman, M. J., Sotgia, B., Bos, J. M., Nistri, S., Sgalambro, A., Grifoni, C., Torricelli, F., Camici, P. G. & Cecchi, F., Aug 16 2011, In : Journal of the American College of Cardiology. 58, 8, p. 839-848 10 p.

Research output: Contribution to journalArticle

Sarcomeres
Myofibrils
Hypertrophic Cardiomyopathy
Mutation
Genotype
71 Citations (Scopus)

Mutation and gender-specific risk in type 2 long QT syndrome: Implications for risk stratification for life-threatening cardiac events in patients with long QT syndrome

Migdalovich, D., Moss, A. J., Lopes, C. M., Costa, J., Ouellet, G., Barsheshet, A., McNitt, S., Polonsky, S., Robinson, J. L., Zareba, W., Ackerman, M. J., Benhorin, J., Kaufman, E. S., Platonov, P. G., Shimizu, W., Towbin, J. A., Vincent, G. M., Wilde, A. A. M. & Goldenberg, I., Oct 2011, In : Heart Rhythm. 8, 10, p. 1537-1543 7 p.

Research output: Contribution to journalArticle

Long QT Syndrome
Mutation
Sudden Cardiac Death
Heart Arrest
Parturition
32 Citations (Scopus)

PLN-encoded phospholamban mutation in a large cohort of hypertrophic cardiomyopathy cases: Summary of the literature and implications for genetic testing

Landstrom, A. P., Adekola, B. A., Bos, J. M., Ommen, S. R. & Ackerman, M. J., Jan 2011, In : American Heart Journal. 161, 1, p. 165-171 7 p.

Research output: Contribution to journalArticle

Hypertrophic Cardiomyopathy
Genetic Testing
Mutation
Genetic Promoter Regions
phospholamban
55 Citations (Scopus)

Prevalence and clinical correlates of QT prolongation in patients with hypertrophic cardiomyopathy

Johnson, J. N., Grifoni, C., Bos, J. M., Saber-Ayad, M., Ommen, S. R., Nistri, S., Cecchi, F., Olivotto, I. & Ackerman, M. J., May 2011, In : European Heart Journal. 32, 9, p. 1114-1120 7 p.

Research output: Contribution to journalArticle

Hypertrophic Cardiomyopathy
Genotype
Ventricular Outflow Obstruction
Sudden Cardiac Death
Risk Management
30 Citations (Scopus)

QTc values among children and adolescents presenting to the emergency department

Van Dorn, C. S., Johnson, J. N., Taggart, N. W., Thorkelson, L. & Ackerman, M. J., Dec 2011, In : Pediatrics. 128, 6

Research output: Contribution to journalArticle

Hospital Emergency Service
Syncope
Electrocardiography
Long QT Syndrome
Hospital Distribution Systems
45 Citations (Scopus)

R231C mutation in KCNQ1 causes long QT syndrome type 1 and familial atrial fibrillation

Bartos, D. C., Duchatelet, S., Burgess, D. E., Klug, D., Denjoy, I., Peat, R., Lupoglazoff, J. M., Fressart, V., Berthet, M., Ackerman, M. J., January, C. T., Guicheney, P. & Delisle, B. P., Jan 2011, In : Heart Rhythm. 8, 1, p. 48-55 8 p.

Research output: Contribution to journalArticle

Romano-Ward Syndrome
Atrial Fibrillation
Mutation
Single Nucleotide Polymorphism
HEK293 Cells
80 Citations (Scopus)

Risk factors for recurrent syncope and subsequent fatal or near-fatal events in children and adolescents with long QT syndrome

Liu, J. F., Jons, C., Moss, A. J., McNitt, S., Peterson, D. R., Qi, M., Zareba, W., Robinson, J. L., Barsheshet, A., Ackerman, M. J., Benhorin, J., Kaufman, E. S., Locati, E. H., Napolitano, C., Priori, S. G., Schwartz, P. J., Towbin, J., Vincent, M., Zhang, L. & Goldenberg, I., Feb 22 2011, In : Journal of the American College of Cardiology. 57, 8, p. 941-950 10 p.

Research output: Contribution to journalArticle

Long QT Syndrome
Syncope
Romano-Ward Syndrome
Genotype
Risk Reduction Behavior
41 Citations (Scopus)

Risk of recurrent cardiac events after onset of menopause in women with congenital long-QT syndrome types 1 and 2

Buber, J., Mathew, J., Moss, A. J., Hall, W. J., Barsheshet, A., McNitt, S., Robinson, J. L., Zareba, W., Ackerman, M. J., Kaufman, E. S., Luria, D., Eldar, M., Towbin, J. A., Vincent, M. & Goldenberg, I., Jun 21 2011, In : Circulation. 123, 24, p. 2784-2791 8 p.

Research output: Contribution to journalArticle

Romano-Ward Syndrome
Menopause
Syncope
Postmenopause
Long QT Syndrome
8 Citations (Scopus)

Risk of syncope in family members who are genotype-negative for a family-associated Long-QT syndrome mutation

Barsheshet, A., Moss, A. J., McNitt, S., Polonsky, S., Lopes, C. M., Zareba, W., Robinson, J. L., Ackerman, M. J., Benhorin, J., Kaufman, E. S., Towbin, J. A., Vincent, G. M., Qi, M. & Goldenberg, I., Oct 2011, In : Circulation: Cardiovascular Genetics. 4, 5, p. 491-499 9 p.

Research output: Contribution to journalArticle

Long QT Syndrome
Syncope
Genotype
Mutation
Sudden Cardiac Death
5 Citations (Scopus)

Role of genetic testing for sudden death predisposing heart conditions in athletes

Landstrom, A. P., Tester, D. J. & Ackerman, M. J., 2011, Sports Cardiology Essentials: Evaluation, Management and Case Studies. Springer New York, p. 85-100 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Genetic Testing
Sudden Death
Athletes
8 Citations (Scopus)

Slow QT interval adaptation to heart rate changes in normal ambulatory subjects

Razak, E., Buncová, M., Shusterman, V., Winter, B., Shen, W. K., Ackerman, M. J., Donovan, T., Lampert, R. & Němec, J., Apr 2011, In : Annals of Noninvasive Electrocardiology. 16, 2, p. 148-155 8 p.

Research output: Contribution to journalArticle

Heart Rate
Population
Linear Models
Healthy Volunteers
Nonlinear Dynamics
18 Citations (Scopus)
Genetic Testing
Noise
Mutation
Sudden Cardiac Death
Genetic Background
20 Citations (Scopus)

The common African American polymorphism SCN5A-S1103Y interacts with mutation SCN5A-R680h to increase late Na current

Cheng, J., Tester, D. J., Tan, B. H., Valdivia, C. R., Kroboth, S., Ye, B., January, C. T., Ackerman, M. J. & Makielski, J. C., May 2011, In : Physiological Genomics. 43, 9, p. 461-466 6 p.

Research output: Contribution to journalArticle

Sudden Death
African Americans
Acidosis
Mutation
Cardiac Arrhythmias
67 Citations (Scopus)

The diagnostic utility of recovery phase QTc during treadmill exercise stress testing in the evaluation of long QT syndrome

Horner, J. M., Horner, M. M. & Ackerman, M. J., Nov 2011, In : Heart Rhythm. 8, 11, p. 1698-1704 7 p.

Research output: Contribution to journalArticle

Long QT Syndrome
Exercise
Exercise Test
Genotype
159 Citations (Scopus)

Transient outward current (I to) gain-of-function mutations in the KCND3-encoded Kv4.3 potassium channel and Brugada syndrome

Giudicessi, J. R., Ye, D., Tester, D. J., Crotti, L., Mugione, A., Nesterenko, V. V., Albertson, R. M., Antzelevitch, C., Schwartz, P. J. & Ackerman, M. J., Jul 2011, In : Heart Rhythm. 8, 7, p. 1024-1032 9 p.

Research output: Contribution to journalArticle

Shal Potassium Channels
Brugada Syndrome
Mutation
Action Potentials
Genotype
50 Citations (Scopus)

Unexplained drownings and the cardiac channelopathies: A molecular autopsy series

Tester, D. J., Medeiros-Domingo, A., Will, M. L. & Ackerman, M. J., 2011, In : Mayo Clinic Proceedings. 86, 10, p. 941-947 7 p.

Research output: Contribution to journalArticle

Channelopathies
Autopsy
Mutation
Long QT Syndrome
Ryanodine Receptor Calcium Release Channel