Michael John Ackerman, MD, PhD, FACC

  • 35999 Citations
  • 105 Scopus h-Index
1991 …2020

Research output per year

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Research Output

Idiopathic Restrictive Cardiomyopathy in Children and Young Adults

Anderson, H. N., Cetta, F., Driscoll, D. J., Olson, T. M., Ackerman, M. J. & Johnson, J. N., Jan 1 2018, (Accepted/In press) In : American Journal of Cardiology.

Research output: Contribution to journalArticle

2 Scopus citations

Impact of clinical decision support preventing the use of QT-prolonging medications for patients at risk for torsade de pointes

Sorita, A., Bos, J. M., Morlan, B. W., Tarrell, R. F., Ackerman, M. J. & Caraballo, P., 2015, In : Journal of the American Medical Informatics Association. 22, e1, p. e21-e27

Research output: Contribution to journalArticle

17 Scopus citations

Impact of genetics on the clinical management of channelopathies

Schwartz, P. J., Ackerman, M. J., George, A. L. & Wilde, A. A. M., Jul 16 2013, In : Journal of the American College of Cardiology. 62, 3, p. 169-180 12 p.

Research output: Contribution to journalReview article

173 Scopus citations

Impact of Genotype on the Occurrence of Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy

Bongini, C., Ferrantini, C., Girolami, F., Coppini, R., Arretini, A., Targetti, M., Bardi, S., Castelli, G., Torricelli, F., Cecchi, F., Ackerman, M. J., Padeletti, L., Poggesi, C. & Olivotto, I., Sep 22 2015, (Accepted/In press) In : American Journal of Cardiology.

Research output: Contribution to journalArticle

8 Scopus citations

Impact of left ventricular hypertrophy on QT prolongation and associated mortality

Haugaa, K. H., Bos, J. M., Borkenhagen, E. J., Tarrell, R. F., Morlan, B. W., Caraballo, P. & Ackerman, M. J., Nov 1 2014, In : Heart Rhythm. 11, 11, p. 1957-1965 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Impact of Septal Myectomy on Left Atrial Volume and Left Ventricular Diastolic Filling Patterns: An Echocardiographic Study of Young Patients with Obstructive Hypertrophic Cardiomyopathy

Menon, S. C., Ackerman, M. J., Ommen, S. R., Cabalka, A. K., Hagler, D. J., O'Leary, P. W., Dearani, J. A., Cetta, F. & Eidem, B. W., Jun 1 2008, In : Journal of the American Society of Echocardiography. 21, 6, p. 684-688 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

Implantable cardioverter-defibrillator explantation for overdiagnosed or overtreated congenital long QT syndrome

Gaba, P., Martijn Bos, J., Cannon, B. C., Cha, Y-M., Friedman, P. A., Asirvatham, S. J. & Ackerman, M. J., Apr 1 2016, In : Heart Rhythm. 13, 4, p. 879-885 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Implantable cardioverter-defibrillators in previously undiagnosed patients with catecholaminergic polymorphic ventricular tachycardia resuscitated from sudden cardiac arrest

Van Der Werf, C., Lieve, K. V., Bos, J. M., Lane, C. M., Denjoy, I., Roses-Noguer, F., Aiba, T., Wada, Y., Ingles, J., Leren, I. S., Rudic, B., Schwartz, P. J., Maltret, A., Sacher, F., Skinner, J. R., Krahn, A. D., Roston, T. M., Tfelt-Hansen, J., Swan, H., Robyns, T. & 17 others, Ohno, S., Roberts, J. D., Van Den Berg, M. P., Kammeraad, J. A., Probst, V., Kannankeril, P. J., Blom, N. A., Behr, E. R., Borggrefe, M., Haugaa, K. H., Semsarian, C., Horie, M., Shimizu, W., Till, J. A., Leenhardt, A., Ackerman, M. J. & Wilde, A. A., Sep 14 2019, In : European heart journal. 40, 35, p. 2953-2961 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Implantable cardioverter defibrillator therapy for congenital long QT syndrome: A single-center experience

Horner, J. M., Kinoshita, M., Webster, T. L., Haglund, C. M., Friedman, P. A. & Ackerman, M. J., Nov 1 2010, In : Heart rhythm. 7, 11, p. 1616-1622 7 p.

Research output: Contribution to journalArticle

65 Scopus citations

Implantable cardioverter-defibrillator use in catecholaminergic polymorphic ventricular tachycardia: A systematic review

Roston, T. M., Jones, K., Hawkins, N. M., Bos, J. M., Schwartz, P. J., Perry, F., Ackerman, M. J., Laksman, Z. W. M., Kaul, P., Lieve, K. V. V., Atallah, J., Krahn, A. D. & Sanatani, S., Dec 1 2018, In : Heart Rhythm. 15, 12, p. 1791-1799 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Importance of Variant Interpretation in Whole-Exome Molecular Autopsy: Population-Based Case Series

Shanks, G. W., Tester, D. J., Ackerman, J. P., Simpson, M. A., Behr, E. R., White, S. M. & Ackerman, M. J., Jun 19 2018, In : Circulation. 137, 25, p. 2705-2715 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Inaccurate diagnosis of Brugada syndrome in a healthy woman based on SCN5A mutation classification

Warring, S. K., Anderson, H. N., Bos, J. M. & Ackerman, M. J., 2017, (Accepted/In press) In : HeartRhythm Case Reports.

Research output: Contribution to journalArticle

2 Scopus citations

Incidence, cause, and comparative frequency of sudden cardiac death in national collegiate athletic association athletes a decade in review

Harmon, K. G., Asif, I. M., Maleszewski, J., Owens, D. S., Prutkin, J. M., Salerno, J. C., Zigman, M. L., Ellenbogen, R., Rao, A. L., Ackerman, M. J. & Drezner, J. A., 2015, In : Circulation. 132, 1, p. 10-19 10 p.

Research output: Contribution to journalArticle

172 Scopus citations

Incidence and Etiology of Sudden Cardiac Arrest and Death in High School Athletes in the United States

Harmon, K. G., Asif, I. M., Maleszewski, J., Owens, D. S., Prutkin, J. M., Salerno, J. C., Zigman, M. L., Ellenbogen, R., Rao, A. L., Ackerman, M. J. & Drezner, J. A., Nov 1 2016, In : Mayo Clinic Proceedings. 91, 11, p. 1493-1502 10 p.

Research output: Contribution to journalArticle

25 Scopus citations
2 Scopus citations

Inherited and de novo mutations in the cardiac actin gene cause hypertrophic cardiomyopathy

Olson, T. M., Doan, T. P., Kishimoto, N. Y., Whitby, F. G., Ackerman, M. J. & Fananapazir, L., Jan 1 2000, In : Journal of Molecular and Cellular Cardiology. 32, 9, p. 1687-1694 8 p.

Research output: Contribution to journalArticle

165 Scopus citations

Inherited arrhythmias: A National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affecting ion channel function

Lehnart, S. E., Ackerman, M. J., Benson, D. W., Brugada, R., Clancy, C. E., Donahue, J. K., George, A. L., Grant, A. O., Groft, S. C., January, C. T., Lathrop, D. A., Lederer, W. J., Makielski, J. C., Mohler, P. J., Moss, A., Nerbonne, J. M., Olson, T. M., Przywara, D. A., Towbin, J. A., Wang, L. H. & 1 others, Marks, A. R., Nov 1 2007, In : Circulation. 116, 20, p. 2325-2345 21 p.

Research output: Contribution to journalArticle

198 Scopus citations

In reply

Sheeler, R. D., Ackerman, M. J., Richelson, E., Nelson, T. K., Staab, J. P., Tangalos, E. G., Dieser, L. M. & Cunningham, J. L., Apr 2013, In : Mayo Clinic proceedings. 88, 4, 1 p.

Research output: Contribution to journalLetter

Institution-wide QT alert system identifies patients with a high risk of mortality

Haugaa, K. H., Bos, J. M., Tarrell, R. F., Morlan, B. W., Caraballo, P. J. & Ackerman, M. J., Apr 2013, In : Mayo Clinic proceedings. 88, 4, p. 315-325 11 p.

Research output: Contribution to journalArticle

76 Scopus citations

Interaction with GM130 during HERG ion channel trafficking: Disruption by type 2 congenital long QT syndrome mutations

Roti Roti, E. C., Myers, C. D., Ayers, R. A., Boatman, D. E., Delfosse, S. A., Chan, E. K. L., Ackerman, M. J., January, C. T. & Robertson, G. A., Dec 6 2002, In : Journal of Biological Chemistry. 277, 49, p. 47779-47785 7 p.

Research output: Contribution to journalArticle

61 Scopus citations

International criteria for electrocardiographic interpretation in athletes: Consensus statement

Drezner, J. A., Sharma, S., Baggish, A., Papadakis, M., Wilson, M. G., Prutkin, J. M., Gerche, A. L., Ackerman, M. J., Borjesson, M., Salerno, J. C., Asif, I. M., Owens, D. S., Chung, E. H., Emery, M. S., Froelicher, V. F., Heidbuchel, H., Adamuz, C., Asplund, C. A., Cohen, G., Harmon, K. G. & 13 others, Marek, J. C., Molossi, S., Niebauer, J., Pelto, H. F., Perez, M. V., Riding, N. R., Saarel, T., Schmied, C. M., Shipon, D. M., Stein, R., Vetter, V. L., Pelliccia, A. & Corrado, D., May 1 2017, In : British Journal of Sports Medicine. 51, 9, p. 704-731 28 p.

Research output: Contribution to journalArticle

67 Scopus citations

International recommendations for electrocardiographic interpretation in athletes

Sharma, S., Drezner, J. A., Baggish, A., Papadakis, M., Wilson, M. G., Prutkin, J. M., La Gerche, A., Ackerman, M. J., Borjesson, M., Salerno, J. C., Asif, I. M., Owens, D. S., Chung, E. H., Emery, M. S., Froelicher, V. F., Heidbuchel, H., Adamuz, C., Asplund, C. A., Cohen, G., Harmon, K. G. & 13 others, Marek, J. C., Molossi, S., Niebauer, J., Pelto, H. F., Perez, M. V., Riding, N. R., Saarel, T., Schmied, C. M., Shipon, D. M., Stein, R., Vetter, V. L., Pelliccia, A. & Corrado, D., Apr 21 2018, In : European Heart Journal. 39, 16, p. 1466-1480 15 p.

Research output: Contribution to journalArticle

59 Scopus citations

International Recommendations for Electrocardiographic Interpretation in Athletes

Sharma, S., Drezner, J. A., Baggish, A., Papadakis, M., Wilson, M. G., Prutkin, J. M., La Gerche, A., Ackerman, M. J., Borjesson, M., Salerno, J. C., Asif, I. M., Owens, D. S., Chung, E. H., Emery, M. S., Froelicher, V. F., Heidbuchel, H., Adamuz, C., Asplund, C. A., Cohen, G., Harmon, K. G. & 13 others, Marek, J. C., Molossi, S., Niebauer, J., Pelto, H. F., Perez, M. V., Riding, N. R., Saarel, T., Schmied, C. M., Shipon, D. M., Stein, R., Vetter, V. L., Pelliccia, A. & Corrado, D., Feb 28 2017, In : Journal of the American College of Cardiology. 69, 8, p. 1057-1075 19 p.

Research output: Contribution to journalReview article

95 Scopus citations

International Triadin Knockout Syndrome Registry

Clemens, D. J., Tester, D. J., Giudicessi, J. R., Bos, J. M., Rohatgi, R. K., Abrams, D. J., Balaji, S., Crotti, L., Faure, J., Napolitano, C., Priori, S. G., Probst, V., Rooryck-Thambo, C., Roux-Buisson, N., Sacher, F., Schwartz, P. J., Silka, M. J., Walsh, M. A. & Ackerman, M. J., Feb 1 2019, In : Circulation. Genomic and precision medicine. 12, 2, p. e002419

Research output: Contribution to journalArticle

3 Scopus citations

Intracellular Signaling and Regulation of Cardiac Ion Channels

Khositseth, A., Clapham, D. E. & Ackerman, M. J., Jun 2004, Cardiac Electrophysiology: Fourth Edition. Elsevier Inc., p. 33-41 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

13 Scopus citations

Intragenic suppression of trafficking-defective KCNH2 channels associated with long QT syndrome

Delisle, B. P., Slind, J. K., Kilby, J. A., Anderson, C. L., Anson, B. D., Balijepalli, R. C., Tester, D. J., Ackerman, M. J., Kamp, T. J. & January, C. T., Jul 1 2005, In : Molecular pharmacology. 68, 1, p. 233-240 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

In Vivo Analysis of Troponin C Knock-In (A8V) Mice: Evidence that TNNC1 Is a Hypertrophic Cardiomyopathy Susceptibility Gene

Martins, A. S., Parvatiyar, M. S., Feng, H. Z., Bos, J. M., Gonzalez-Martinez, D., Vukmirovic, M., Turna, R. S., Sanchez-Gonzalez, M. A., Badger, C. D., Zorio, D. A. R., Singh, R. K., Wang, Y., Jin, J. P., Ackerman, M. J. & Pinto, J. R., Oct 1 2015, In : Circulation: Cardiovascular Genetics. 8, 5, p. 653-664 12 p.

Research output: Contribution to journalArticle

22 Scopus citations

Irritable bowel syndrome patients have SCN5A channelopathies that lead to decreased Nav1.5 current and mechanosensitivity

Strege, P. R., Mazzone, A., Bernard, C. E., Neshatian, L., Gibbons, S. J., Saito Loftus, Y. A., Tester, D. J., Calvert, M. L., Mayer, E. A., Chang, L., Ackerman, M. J., Beyder, A. & Farrugia, G., Apr 1 2018, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 314, 4, p. G494-G503

Research output: Contribution to journalArticle

9 Scopus citations

Is sudden unexplained nocturnal death syndrome in Southern China a cardiac sodium channel dysfunction disorder?

Liu, C., Tester, D. J., Hou, Y., Wang, W., Lv, G., Ackerman, M. J., Makielski, J. C. & Cheng, J., Mar 1 2014, In : Forensic Science International. 236, p. 38-45 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Junctophilin-2 expression silencing causes cardiocyte hypertrophy and abnormal intracellular calcium-handling

Landstrom, A. P., Kellen, C. A., Dixit, S. S., Van Oort, R. J., Garbino, A., Weisleder, N., Ma, J., Wehrens, X. H. T. & Ackerman, M. J., Mar 1 2011, In : Circulation: Heart Failure. 4, 2, p. 214-223 10 p.

Research output: Contribution to journalArticle

62 Scopus citations

Junctophilin-2 is necessary for T-tubule maturation during mouse heart development

Reynolds, J. O., Chiang, D. Y., Wang, W., Beavers, D. L., Dixit, S. S., Skapura, D. G., Landstrom, A. P., Song, L. S., Ackerman, M. J. & Wehrens, X. H. T., Oct 1 2013, In : Cardiovascular research. 100, 1, p. 44-53 10 p.

Research output: Contribution to journalArticle

54 Scopus citations

J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge

Antzelevitch, C., Yan, G. X., Ackerman, M. J., Borggrefe, M., Corrado, D., Guo, J., Gussak, I., Hasdemir, C., Horie, M., Huikuri, H., Ma, C., Morita, H., Nam, G. B., Sacher, F., Shimizu, W., Viskin, S. & Wilde, A. A. M., Oct 1 2016, In : Journal of Arrhythmia. 32, 5, p. 315-339 25 p.

Research output: Contribution to journalArticle

56 Scopus citations

J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge

Antzelevitch, C., Yan, G. X., Ackerman, M. J., Borggrefe, M., Corrado, D., Guo, J., Gussak, I., Hasdemir, C., Horie, M., Huikuri, H., Ma, C., Morita, H., Nam, G. B., Sacher, F., Shimizu, W., Viskin, S. & Wilde, A. A. M., Apr 1 2017, In : Europace. 19, 4, p. 665-694 30 p.

Research output: Contribution to journalArticle

61 Scopus citations

J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge. Endorsed by the Asia Pacific Heart Rhythm Society (APHRS), the European Heart Rhythm Association (EHRA), the Heart Rhythm Society (HRS), and the Latin American Society of Cardiac Pacing and Electrophysiology (Sociedad Latinoamericana de Estimulación Cardíaca y Elect

Antzelevitch, C., Yan, G. X., Ackerman, M. J., Borggrefe, M., Corrado, D., Guo, J., Gussak, I., Hasdemir, C., Horie, M., Huikuri, H., Ma, C., Morita, H., Nam, G. B., Sacher, F., Shimizu, W., Viskin, S. & Wilde, A. A. M., 2016, (Accepted/In press) In : Heart Rhythm.

Research output: Contribution to journalArticle

94 Scopus citations

J wave syndrome-susceptibility mutations versus benign rare variants: How do we decide?

Kapplinger, J. D., Tester, D. J. & Ackerman, M. J., Jan 1 2016, J Wave Syndromes: Brugada and Early Repolarization Syndromes. Springer International Publishing, p. 91-120 30 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

KCNJ2 mutations in arrhythmia patients referred for LQT testing: A mutation T305A with novel effect on rectification properties

Eckhardt, L. L., Farley, A. L., Rodriguez, E., Ruwaldt, K., Hammill, D., Tester, D. J., Ackerman, M. J. & Makielski, J. C., Mar 1 2007, In : Heart rhythm. 4, 3, p. 323-329 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

KCNQ1 p.L353L affects splicing and modifies the phenotype in a founder population with long QT syndrome type 1

Kapplinger, J. D., Erickson, A., Asuri, S., Tester, D. J., McIntosh, S., Kerr, C. R., Morrison, J., Tang, A., Sanatani, S., Arbour, L. & Ackerman, M. J., Jun 1 2017, In : Journal of Medical Genetics. 54, 6, p. 390-398 9 p.

Research output: Contribution to journalArticle

6 Scopus citations
Open Access
3 Scopus citations

Left axis deviation in children without previously known heart disease

Schneider, A. E., Cannon, B. C., Johnson, J. N., Ackerman, M. J. & Wackel, P. L., Mar 1 2018, In : Pediatrics. 141, 3, e20171970.

Research output: Contribution to journalArticle

1 Scopus citations

Left cardiac sympathetic denervation for recurrent ventricular tachyarrhythmias in children with congenital heart disease

Bonura, E. D., Moir, C., Ackerman, M. J. & Wackel, P., Jan 1 2019, In : HeartRhythm Case Reports.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Left cardiac sympathetic denervation for the treatment of long QT syndrome and catecholaminergic polymorphic ventricular tachycardia using video-assisted thoracic surgery

Collura, C. A., Johnson, J. N., Moir, C. & Ackerman, M. J., Jun 1 2009, In : Heart rhythm. 6, 6, p. 752-759 8 p.

Research output: Contribution to journalArticle

219 Scopus citations

Left cardiac sympathetic denervation in a pediatric patient with hypertrophic cardiomyopathy and recurrent ventricular fibrillation

Johnson, J. N., Harris, K. M., Moir, C., Lau, Y. R. & Ackerman, M. J., Oct 1 2011, In : Heart rhythm. 8, 10, p. 1591-1594 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Left cardiac sympathetic denervation in long QT syndrome: Analysis of therapeutic nonresponders

Bos, J. M., Bos, K. M., Johnson, J. N., Moir, C. & Ackerman, M. J., Aug 1 2013, In : Circulation: Arrhythmia and Electrophysiology. 6, 4, p. 705-711 7 p.

Research output: Contribution to journalArticle

48 Scopus citations

Left Ventricular Isovolumetric Relaxation Time Is Prolonged in Fetal Long-QT Syndrome

Clur, S. A. B., Vink, A. S., Etheridge, S. P., Robles De Medina, P. G., Rydberg, A., Ackerman, M. J., Wilde, A. A., Blom, N. A., Benson, D. W., Herberg, U., Donofrio, M. T. & Cuneo, B. F., Apr 1 2018, In : Circulation: Arrhythmia and Electrophysiology. 11, 4, e005797.

Research output: Contribution to journalArticle

1 Scopus citations

Left ventricular noncompaction syndrome masquerading or misdiagnosed as congenital long QT syndrome: Remember QT prolongation does not equal long QT syndrome

Coleman, M. A., Bos, J. M., Phillips, S. D., Souza, J. J. & Ackerman, M. J., Sep 1 2011, In : Congenital Heart Disease. 6, 5, p. 492-498 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
1 Scopus citations

Lidocaine attenuation testing: An in vivo investigation of putative LQT3-associated variants in the SCN5A-encoded sodium channel

Anderson, H. N., Bos, J. M., Kapplinger, J. D., Meskill, J. M., Ye, D. & Ackerman, M. J., 2017, (Accepted/In press) In : Heart Rhythm.

Research output: Contribution to journalArticle

6 Scopus citations

Linking the heart and the brain: Neurodevelopmental disorders in patients with catecholaminergic polymorphic ventricular tachycardia

Lieve, K. V. V., Verhagen, J. M. A., Wei, J., Bos, J. M., van der Werf, C., Rosés i Noguer, F., Mancini, G. M. S., Guo, W., Wang, R., van den Heuvel, F., Frohn-Mulder, I. M. E., Shimizu, W., Nogami, A., Horigome, H., Roberts, J. D., Leenhardt, A., Crijns, H. J. G., Blank, A. C., Aiba, T., Wiesfeld, A. C. P. & 7 others, Blom, N. A., Sumitomo, N., Till, J., Ackerman, M. J., Chen, S. R. W., van de Laar, I. M. B. H. & Wilde, A. A. M., Feb 1 2019, In : Heart Rhythm. 16, 2, p. 220-228 9 p.

Research output: Contribution to journalArticle

2 Scopus citations