Michael John Ackerman, MD, PhD, FACC

  • 35918 Citations
  • 105 Scopus h-Index
1991 …2020

Research output per year

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Research Output

2010

The prevalence and diagnostic/prognostic utility of sinus arrhythmia in the evaluation of congenital long QT syndrome

Johnson, J. N. & Ackerman, M. J., Dec 2010, In : Heart Rhythm. 7, 12, p. 1785-1789 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Transient QT interval prolongation in an infant with Simpson-Golabi-Behmel syndrome

Gertsch, E., Kirmani, S., Ackerman, M. J. & Babovic-Vuksanovic, D., Sep 2010, In : American Journal of Medical Genetics, Part A. 152, 9, p. 2379-2382 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Trigger-specific risk factors and response to therapy in long QT syndrome type 2

Kim, J. A., Lopes, C. M., Moss, A. J., McNitt, S., Barsheshet, A., Robinson, J. L., Zareba, W., Ackerman, M. J., Kaufman, E. S., Towbin, J. A., Vincent, M. & Goldenberg, I., Dec 2010, In : Heart Rhythm. 7, 12, p. 1797-1805 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Z-Disc Genes in Hypertrophic Cardiomyopathy. Stretching the Cardiomyopathies?

Bos, J. M. & Ackerman, M. J., Mar 16 2010, In : Journal of the American College of Cardiology. 55, 11, p. 1136-1138 3 p.

Research output: Contribution to journalArticle

25 Scopus citations
2011

Anesthetic management of patients with Brugada syndrome: A case series and literature review

Kloesel, B., Ackerman, M. J., Sprung, J., Narr, B. J. & Weingarten, T. N., Sep 2011, In : Canadian Journal of Anesthesia. 58, 9, p. 824-836 13 p.

Research output: Contribution to journalArticle

36 Scopus citations

Clinical spectrum in a family with tropomyosin-mediated hypertrophic cardiomyopathy and sudden death in childhood

Makhoul, M., Ackerman, M. J., Atkins, D. L. & Law, I. H., Feb 2011, In : Pediatric Cardiology. 32, 2, p. 215-220 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Disrupted junctional membrane complexes and hyperactive ryanodine receptors after acute junctophilin knockdown in mice

Van Oort, R. J., Garbino, A., Wang, W., Dixit, S. S., Landstrom, A. P., Gaur, N., De Almeida, A. C., Skapura, D. G., Rudy, Y., Burns, A. R., Ackerman, M. J. & Wehrens, X. H. T., Mar 8 2011, In : Circulation. 123, 9, p. 979-988 10 p.

Research output: Contribution to journalArticle

149 Scopus citations

Distinguishing arrhythmogenic right ventricular cardiomyopathy/dysplasia- associated mutations from background genetic noise

Kapplinger, J. D., Landstrom, A. P., Salisbury, B. A., Callis, T. E., Pollevick, G. D., Tester, D. J., Cox, M. G. P. J., Bhuiyan, Z., Bikker, H., Wiesfeld, A. C. P., Hauer, R. N. W., Van Tintelen, J. P., Jongbloed, J. D. H., Calkins, H., Judge, D. P., Wilde, A. A. M. & Ackerman, M. J., Jun 7 2011, In : Journal of the American College of Cardiology. 57, 23, p. 2317-2327 11 p.

Research output: Contribution to journalArticle

197 Scopus citations

Dysferlin, annexin A1, and mitsugumin 53 are upregulated in muscular dystrophy and localize to longitudinal tubules of the T-system with stretch

Waddell, L. B., Lemckert, F. A., Zheng, X. F., Tran, J., Evesson, F. J., Hawkes, J. M., Lek, A., Street, N. E., Lin, P., Clarke, N. F., Landstrom, A. P., Ackerman, M. J., Weisleder, N., Ma, J., North, K. N. & Cooper, S. T., Apr 2011, In : Journal of Neuropathology and Experimental Neurology. 70, 4, p. 302-313 12 p.

Research output: Contribution to journalArticle

53 Scopus citations

Electrocardiographic and oximetric changes during partial complex and generalized seizures

Moseley, B. D., Wirrell, E. C., Nickels, K. C., Johnson, J. N., Ackerman, M. J. & Britton, J., Aug 2011, In : Epilepsy Research. 95, 3, p. 237-245 9 p.

Research output: Contribution to journalArticle

56 Scopus citations

Electrocardiographic changes and arrhythmias following percutaneous atrial septal defect and patent foramen ovale device closure

Johnson, J. N., Marquardt, M. L., Ackerman, M. J., Asirvatham, S. J., Reeder, G. S., Cabalka, A. K., Cetta, F. & Hagler, D. J., Aug 1 2011, In : Catheterization and Cardiovascular Interventions. 78, 2, p. 254-261 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Genetic testing for potentially lethal, highly treatable inherited cardiomyopathies/channelopathies in clinical practice

Tester, D. J. & Ackerman, M. J., Mar 8 2011, In : Circulation. 123, 9, p. 1021-1037 17 p.

Research output: Contribution to journalArticle

142 Scopus citations

Genotype-specific QT correction for heart rate and the risk of life-threatening cardiac events in adolescents with congenital long-QT syndrome

Barsheshet, A., Peterson, D. R., Moss, A. J., Schwartz, P. J., Kaufman, E. S., McNitt, S., Polonsky, S., Buber, J., Zareba, W., Robinson, J. L., Ackerman, M. J., Benhorin, J., Towbin, J. A., Vincent, G. M., Zhang, L. & Goldenberg, I., Aug 2011, In : Heart Rhythm. 8, 8, p. 1207-1213 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Holter monitoring in the evaluation of congenital long QT syndrome

Mauriello, D. A., Johnson, J. N. & Ackerman, M. J., Sep 2011, In : PACE - Pacing and Clinical Electrophysiology. 34, 9, p. 1100-1104 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies

Ackerman, M. J., Priori, S. G., Willems, S., Berul, C., Brugada, R., Calkins, H., Camm, A. J., Ellinor, P. T., Gollob, M., Hamilton, R., Hershberger, R. E., Judge, D. P., Le Marec, H., McKenna, W. J., Schulze-Bahr, E., Semsarian, C., Towbin, J. A., Watkins, H., Wilde, A., Wolpert, C. & 2 others, Zipes, D. P. & Olson, S., Aug 2011, In : Europace. 13, 8, p. 1077-1109 33 p.

Research output: Contribution to journalArticle

436 Scopus citations

HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies: This document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA)

Ackerman, M. J., Priori, S. G., Willems, S., Berul, C., Brugada, R., Calkins, H., Camm, A. J., Ellinor, P. T., Gollob, M., Hamilton, R., Hershberger, R. E., Judge, D. P., Le Marec, H., McKenna, W. J., Schulze-Bahr, E., Semsarian, C., Towbin, J. A., Watkins, H., Wilde, A., Wolpert, C. & 1 others, Zipes, D. P., Aug 2011, In : Heart Rhythm. 8, 8, p. 1308-1339 32 p.

Research output: Contribution to journalArticle

602 Scopus citations

HRS policy statement: Clinical cardiac electrophysiology fellowship curriculum: Update 2011

Link, M. S., Exner, D. V., Anderson, M., Ackerman, M. J., Al-Ahmad, A., Knight, B. P., Markowitz, S. M., Kaufman, E. S., Haines, D., Asirvatham, S. J., Callans, D. J., Mounsey, J. P., Bogun, F., Narayan, S. M., Krahn, A. D., Mittal, S., Singh, J., Fisher, J. D. & Chugh, S. S., Aug 2011, In : Heart Rhythm. 8, 8, p. 1340-1356 17 p.

Research output: Contribution to journalArticle

9 Scopus citations

Junctophilin-2 expression silencing causes cardiocyte hypertrophy and abnormal intracellular calcium-handling

Landstrom, A. P., Kellen, C. A., Dixit, S. S., Van Oort, R. J., Garbino, A., Weisleder, N., Ma, J., Wehrens, X. H. T. & Ackerman, M. J., Mar 2011, In : Circulation: Heart Failure. 4, 2, p. 214-223 10 p.

Research output: Contribution to journalArticle

62 Scopus citations

Left cardiac sympathetic denervation in a pediatric patient with hypertrophic cardiomyopathy and recurrent ventricular fibrillation

Johnson, J. N., Harris, K. M., Moir, C., Lau, Y. R. & Ackerman, M. J., Oct 2011, In : Heart Rhythm. 8, 10, p. 1591-1594 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Left ventricular noncompaction syndrome masquerading or misdiagnosed as congenital long QT syndrome: Remember QT prolongation does not equal long QT syndrome

Coleman, M. A., Bos, J. M., Phillips, S. D., Souza, J. J. & Ackerman, M. J., Sep 2011, In : Congenital Heart Disease. 6, 5, p. 492-498 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Loss-of-function mutations in the KCNJ8-Encoded Kir6.1 KATP channel and sudden infant death syndrome

Tester, D. J., Tan, B. H., Medeiros-Domingo, A., Song, C., Makielski, J. C. & Ackerman, M. J., Oct 2011, In : Circulation: Cardiovascular Genetics. 4, 5, p. 510-515 6 p.

Research output: Contribution to journalArticle

47 Scopus citations

Microvascular function is selectively impaired in patients with hypertrophic cardiomyopathy and sarcomere myofilament gene mutations

Olivotto, I., Girolami, F., Sciagr, R., Ackerman, M. J., Sotgia, B., Bos, J. M., Nistri, S., Sgalambro, A., Grifoni, C., Torricelli, F., Camici, P. G. & Cecchi, F., Aug 16 2011, In : Journal of the American College of Cardiology. 58, 8, p. 839-848 10 p.

Research output: Contribution to journalArticle

85 Scopus citations

Mutation and gender-specific risk in type 2 long QT syndrome: Implications for risk stratification for life-threatening cardiac events in patients with long QT syndrome

Migdalovich, D., Moss, A. J., Lopes, C. M., Costa, J., Ouellet, G., Barsheshet, A., McNitt, S., Polonsky, S., Robinson, J. L., Zareba, W., Ackerman, M. J., Benhorin, J., Kaufman, E. S., Platonov, P. G., Shimizu, W., Towbin, J. A., Vincent, G. M., Wilde, A. A. M. & Goldenberg, I., Oct 2011, In : Heart Rhythm. 8, 10, p. 1537-1543 7 p.

Research output: Contribution to journalArticle

73 Scopus citations

PLN-encoded phospholamban mutation in a large cohort of hypertrophic cardiomyopathy cases: Summary of the literature and implications for genetic testing

Landstrom, A. P., Adekola, B. A., Bos, J. M., Ommen, S. R. & Ackerman, M. J., Jan 2011, In : American Heart Journal. 161, 1, p. 165-171 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

Prevalence and clinical correlates of QT prolongation in patients with hypertrophic cardiomyopathy

Johnson, J. N., Grifoni, C., Bos, J. M., Saber-Ayad, M., Ommen, S. R., Nistri, S., Cecchi, F., Olivotto, I. & Ackerman, M. J., May 2011, In : European Heart Journal. 32, 9, p. 1114-1120 7 p.

Research output: Contribution to journalArticle

56 Scopus citations

QTc values among children and adolescents presenting to the emergency department

Van Dorn, C. S., Johnson, J. N., Taggart, N. W., Thorkelson, L. & Ackerman, M. J., Dec 2011, In : Pediatrics. 128, 6

Research output: Contribution to journalArticle

31 Scopus citations

R231C mutation in KCNQ1 causes long QT syndrome type 1 and familial atrial fibrillation

Bartos, D. C., Duchatelet, S., Burgess, D. E., Klug, D., Denjoy, I., Peat, R., Lupoglazoff, J. M., Fressart, V., Berthet, M., Ackerman, M. J., January, C. T., Guicheney, P. & Delisle, B. P., Jan 2011, In : Heart Rhythm. 8, 1, p. 48-55 8 p.

Research output: Contribution to journalArticle

45 Scopus citations

Risk factors for recurrent syncope and subsequent fatal or near-fatal events in children and adolescents with long QT syndrome

Liu, J. F., Jons, C., Moss, A. J., McNitt, S., Peterson, D. R., Qi, M., Zareba, W., Robinson, J. L., Barsheshet, A., Ackerman, M. J., Benhorin, J., Kaufman, E. S., Locati, E. H., Napolitano, C., Priori, S. G., Schwartz, P. J., Towbin, J., Vincent, M., Zhang, L. & Goldenberg, I., Feb 22 2011, In : Journal of the American College of Cardiology. 57, 8, p. 941-950 10 p.

Research output: Contribution to journalArticle

81 Scopus citations

Risk of recurrent cardiac events after onset of menopause in women with congenital long-QT syndrome types 1 and 2

Buber, J., Mathew, J., Moss, A. J., Hall, W. J., Barsheshet, A., McNitt, S., Robinson, J. L., Zareba, W., Ackerman, M. J., Kaufman, E. S., Luria, D., Eldar, M., Towbin, J. A., Vincent, M. & Goldenberg, I., Jun 21 2011, In : Circulation. 123, 24, p. 2784-2791 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Risk of syncope in family members who are genotype-negative for a family-associated Long-QT syndrome mutation

Barsheshet, A., Moss, A. J., McNitt, S., Polonsky, S., Lopes, C. M., Zareba, W., Robinson, J. L., Ackerman, M. J., Benhorin, J., Kaufman, E. S., Towbin, J. A., Vincent, G. M., Qi, M. & Goldenberg, I., Oct 2011, In : Circulation: Cardiovascular Genetics. 4, 5, p. 491-499 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Role of genetic testing for sudden death predisposing heart conditions in athletes

Landstrom, A. P., Tester, D. J. & Ackerman, M. J., 2011, Sports Cardiology Essentials: Evaluation, Management and Case Studies. Springer New York, p. 85-100 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

Slow QT interval adaptation to heart rate changes in normal ambulatory subjects

Razak, E., Buncová, M., Shusterman, V., Winter, B., Shen, W. K., Ackerman, M. J., Donovan, T., Lampert, R. & Němec, J., Apr 2011, In : Annals of Noninvasive Electrocardiology. 16, 2, p. 148-155 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
18 Scopus citations

The common African American polymorphism SCN5A-S1103Y interacts with mutation SCN5A-R680h to increase late Na current

Cheng, J., Tester, D. J., Tan, B. H., Valdivia, C. R., Kroboth, S., Ye, B., January, C. T., Ackerman, M. J. & Makielski, J. C., May 2011, In : Physiological Genomics. 43, 9, p. 461-466 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

The diagnostic utility of recovery phase QTc during treadmill exercise stress testing in the evaluation of long QT syndrome

Horner, J. M., Horner, M. M. & Ackerman, M. J., Nov 2011, In : Heart Rhythm. 8, 11, p. 1698-1704 7 p.

Research output: Contribution to journalArticle

71 Scopus citations

Transient outward current (I to) gain-of-function mutations in the KCND3-encoded Kv4.3 potassium channel and Brugada syndrome

Giudicessi, J. R., Ye, D., Tester, D. J., Crotti, L., Mugione, A., Nesterenko, V. V., Albertson, R. M., Antzelevitch, C., Schwartz, P. J. & Ackerman, M. J., Jul 2011, In : Heart Rhythm. 8, 7, p. 1024-1032 9 p.

Research output: Contribution to journalArticle

165 Scopus citations

Unexplained drownings and the cardiac channelopathies: A molecular autopsy series

Tester, D. J., Medeiros-Domingo, A., Will, M. L. & Ackerman, M. J., 2011, In : Mayo Clinic Proceedings. 86, 10, p. 941-947 7 p.

Research output: Contribution to journalArticle

54 Scopus citations
2012

A mutation in TNNC1-encoded cardiac troponin C, TNNC1-A31S, predisposes to hypertrophic cardiomyopathy and ventricular fibrillation

Parvatiyar, M. S., Landstrom, A. P., Figueiredo-Freitas, C., Potter, J. D., Ackerman, M. J. & Pinto, J. R., Sep 14 2012, In : Journal of Biological Chemistry. 287, 38, p. 31845-31855 11 p.

Research output: Contribution to journalArticle

29 Scopus citations

A novel disease gene for Brugada syndrome: Sarcolemmal membrane-associated protein gene mutations impair intracellular trafficking of hNav1.5

Ishikawa, T., Sato, A., Marcou, C. A., Tester, D. J., Ackerman, M. J., Crotti, L., Schwartz, P. J., On, Y. K., Park, J. E., Nakamura, K., Hiraoka, M., Nakazawa, K., Sakurada, H., Arimura, T., Makita, N. & Kimura, A., Dec 2012, In : Circulation: Arrhythmia and Electrophysiology. 5, 6, p. 1098-1107 10 p.

Research output: Contribution to journalArticle

56 Scopus citations

A novel rare variant in SCN1Bb linked to Brugada syndrome and SIDS by combined modulation of Nav1.5 and Kv4.3 channel currents

Hu, D., Barajas-Martínez, H., Medeiros-Domingo, A., Crotti, L., Veltmann, C., Schimpf, R., Urrutia, J., Alday, A., Casis, O., Pfeiffer, R., Burashnikov, E., Caceres, G., Tester, D. J., Wolpert, C., Borggrefe, M., Schwartz, P., Ackerman, M. J. & Antzelevitch, C., May 2012, In : Heart Rhythm. 9, 5, p. 760-769 10 p.

Research output: Contribution to journalArticle

75 Scopus citations
25 Scopus citations

Call for a sudden cardiac death registry: Should reporting of sudden cardiac death be mandatory?

Campbell, R. M., Berger, S., Ackerman, M. J. & Batra, A. S., Mar 2012, In : Pediatric Cardiology. 33, 3, p. 471-473 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Cardiac channel molecular autopsy: Insights from 173 consecutive cases of autopsy-negative sudden unexplained death referred for postmortem genetic testing

Tester, D. J., Medeiros-Domingo, A., Will, M. L., Haglund, C. M. & Ackerman, M. J., 2012, In : Mayo Clinic Proceedings. 87, 6, p. 524-539 16 p.

Research output: Contribution to journalArticle

148 Scopus citations

Combined assessment of sex- and mutation-specific information for risk stratification in type 1 long QT syndrome

Costa, J., Lopes, C. M., Barsheshet, A., Moss, A. J., Migdalovich, D., Ouellet, G., McNitt, S., Polonsky, S., Robinson, J. L., Zareba, W., Ackerman, M. J., Benhorin, J., Kaufman, E. S., Platonov, P. G., Shimizu, W., Towbin, J. A., Vincent, G. M., Wilde, A. A. M. & Goldenberg, I., Jun 2012, In : Heart Rhythm. 9, 6, p. 892-898 7 p.

Research output: Contribution to journalArticle

37 Scopus citations

Competitive sports participation in athletes with congenital long QT syndrome

Johnson, J. N. & Ackerman, M. J., Aug 22 2012, In : JAMA - Journal of the American Medical Association. 308, 8, p. 764-765 2 p.

Research output: Contribution to journalArticle

62 Scopus citations

Concealed long QT syndrome and intractable partial epilepsy: A case report

Anderson, J. H., Bos, J. M., Meyer, F. B., Cascino, G. D. & Ackerman, M. J., Nov 2012, In : Mayo Clinic Proceedings. 87, 11, p. 1128-1131 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Congenital type 1 long QT syndrome unmasked by a highly caffeinated energy drink

Dufendach, K. A., Horner, J. M., Cannon, B. C. & Ackerman, M. J., Feb 2012, In : Heart Rhythm. 9, 2, p. 285-288 4 p.

Research output: Contribution to journalArticle

21 Scopus citations

Connexin43 mutation causes heterogeneous gap junction loss and sudden infant death

Van Norstrand, D. W., Asimaki, A., Rubinos, C., Dolmatova, E., Srinivas, M., Tester, D. J., Saffitz, J. E., Duffy, H. S. & Ackerman, M. J., Jan 24 2012, In : Circulation. 125, 3, p. 474-481 8 p.

Research output: Contribution to journalReview article

55 Scopus citations

Considerations on safety concerns about citalopram prescribing

Sheeler, R. D., Ackerman, M. J., Richelson, E., Nelson, T. K., Staab, J. P., Tangalos, E. G., Dieser, L. M. & Cunningham, J. L., Nov 2012, In : Mayo Clinic Proceedings. 87, 11, p. 1042-1045 4 p.

Research output: Contribution to journalArticle

20 Scopus citations

Denervation videoscopic left cardiac sympathetic denervation for patients with recurrent ventricular fibrillation/malignant ventricular arrhythmia syndromes besides congenital long-QT syndrome

Coleman, M. A., Bos, J. M., Johnson, J. N., Owen, H. J., Deschamps, C., Moir, C. & Ackerman, M. J., 2012, In : Circulation: Arrhythmia and Electrophysiology. 5, 4, p. 782-788 7 p.

Research output: Contribution to journalArticle

70 Scopus citations