Michael John Ackerman, MD, PhD, FACC

  • 37462 Citations
  • 106 Scopus h-Index
1991 …2020

Research output per year

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Research Output

2015

Phenotype of Children with QT Prolongation Identified Using an Institution-Wide QT Alert System

Anderson, H. N., Bos, J. M., Haugaa, K. H., Morlan, B. W., Tarrell, R. F., Caraballo, P. & Ackerman, M. J., Oct 22 2015, In : Pediatric Cardiology. 36, 7, p. 1350-1356 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Population-based study of QT interval prolongation in patients with rheumatoid arthritis

Chauhan, K., Ackerman, M. J., Crowson, C., Matteson, E. L. & Gabriel, S. E., 2015, In : Clinical and Experimental Rheumatology. 33, 1, p. 84-89 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Post-mortem Whole Exome Sequencing with Gene-Specific Analysis for Autopsy-Negative Sudden Unexplained Death in the Young: A Case Series

Narula, N., Tester, D. J., Paulmichl, A., Maleszewski, J. J. & Ackerman, M. J., Mar 19 2015, In : Pediatric Cardiology. 36, 4, p. 768-778 11 p.

Research output: Contribution to journalArticle

41 Scopus citations
3 Scopus citations

Reply to the editor - Detection of long QT syndrome in the community

Saul, J. P., Schwartz, P. J., Ackerman, M. J. & Triedman, J. K., Jul 1 2015, In : Heart Rhythm. 12, 7, p. e67-e68

Research output: Contribution to journalArticle

1 Scopus citations

Role of common and rare variants in SCN10A: Results from the Brugada syndrome QRS locus gene discovery collaborative study

Behr, E. R., Savio-Galimberti, E., Barc, J., Holst, A. G., Petropoulou, E., Prins, B. P., Jabbari, J., Torchio, M., Berthet, M., Mizusawa, Y., Yang, T., Nannenberg, E. A., Dagradi, F., Weeke, P., Bastiaenan, R., Ackerman, M. J., Haunso, S., Leenhardt, A., Kääb, S., Probst, V. & 12 others, Redon, R., Sharma, S., Wilde, A., Tfelt-Hansen, J., Schwartz, P., Roden, D. M., Bezzina, C. R., Olesen, M., Darbar, D., Guicheney, P., Crotti, L. & Jamshidi, Y., Jun 1 2015, In : Cardiovascular research. 106, 3, p. 520-529 10 p.

Research output: Contribution to journalArticle

66 Scopus citations

Stimulant therapy in children with attention-deficit/hyperactivity disorder and concomitant long QT syndrome: A safe combination?

Rohatgi, R. K., Bos, J. M. & Ackerman, M. J., Aug 1 2015, In : Heart Rhythm. 12, 8, p. 1807-1812 6 p.

Research output: Contribution to journalArticle

7 Scopus citations
5 Scopus citations

Sudden cardiac death in athletes

Semsarian, C., Sweeting, J. & Ackerman, M. J., Aug 1 2015, In : British Journal of Sports Medicine. 49, 15, p. 1017-1023 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Sudden cardiac death in athletes

Semsarian, C., Sweeting, J. & Ackerman, M. J., Mar 18 2015, In : BMJ (Online). 350, h1218.

Research output: Contribution to journalArticle

15 Scopus citations

Surgical Ventricular Septal Myectomy for Patients with Noonan Syndrome and Symptomatic Left Ventricular Outflow Tract Obstruction

Poterucha, J. T., Johnson, J. N., O'Leary, P. W., Connolly, H. M., Niaz, T., Maleszewski, J., Ackerman, M. J., Cetta, F., Dearani, J. A. & Eidem, B. W., Oct 1 2015, In : American Journal of Cardiology. 116, 7, p. 1116-1121 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Ventricular fibrillation after elective surgery in an adolescent with long QT syndrome

Kim, S. J., Pundi, K. N., Bos, J. M. & Ackerman, M. J., Nov 26 2015, In : BMJ Case Reports. 2015, A1719.

Research output: Contribution to journalArticle

1 Scopus citations
12 Scopus citations
2014

A CACNA1C variant associated with reduced voltage-dependent inactivation, increased CaV1.2 channel window current, and arrhythmogenesis

Hennessey, J. A., Boczek, N. J., Jiang, Y. H., Miller, J. D., Patrick, W., Pfeiffer, R., Sutphin, B. S., Tester, D. J., Barajas-Martinez, H., Ackerman, M. J., Antzelevitch, C., Kanter, R. & Pitt, G. S., 2014, In : PloS one. 9, 9, e106982.

Research output: Contribution to journalArticle

23 Scopus citations

A KCNQ1 mutation contributes to the concealed type 1 long QT phenotype by limiting the Kv7.1 channel conformational changes associated with protein kinase A phosphorylation

Bartos, D. C., Giudicessi, J. R., Tester, D. J., Ackerman, M. J., Ohno, S., Horie, M., Gollob, M. H., Burgess, D. E. & Delisle, B. P., Mar 1 2014, In : Heart rhythm. 11, 3, p. 459-468 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Association of common variants in NOS1AP gene with sudden unexplained nocturnal death syndrome in the southern Chinese Han population

Huang, L., Yu, Y., Chen, Y., Tester, D. J., Tang, S., Ackerman, M. J., Yuan, Z. & Cheng, J., Jan 1 2014, In : International Journal of Legal Medicine. 128, 6, p. 933-938 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Atypical atrioventricular nodal reentry tachycardia in a child with polyvalvular dysplasia

Johnson, J. N., Ackerman, M. J. & Cannon, B. C., May 9 2014, In : Cardiology in the Young. 96

Research output: Contribution to journalArticle

Beta-blockers in the treatment of congenital long QT syndrome: Is one beta-blocker superior to another?

Wilde, A. A. M. & Ackerman, M. J., Sep 30 2014, In : Journal of the American College of Cardiology. 64, 13, p. 1359-1361 3 p.

Research output: Contribution to journalEditorial

15 Scopus citations

Cardiac channelopathies and the molecular autopsy

Tester, D. J. & Ackerman, M. J., Mar 1 2014, Forensic Pathology of Infancy and Childhood. Springer New York, p. 899-942 44 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Characterization of a phenotype-based genetic test prediction score for unrelated patients with hypertrophic cardiomyopathy

Bos, J. M., Will, M. L., Gersh, B. J., Kruisselbrink, T. M., Ommen, S. R. & Ackerman, M. J., Jun 2014, In : Mayo Clinic proceedings. 89, 6, p. 727-737 11 p.

Research output: Contribution to journalArticle

66 Scopus citations

Characterization of SEMA3A-encoded semaphorin as a naturally occurring Kv4.3 protein inhibitor and its contribution to Brugada syndrome

Boczek, N. J., Ye, D., Johnson, E. K., Wang, W., Crotti, L., Tester, D. J., Dagradi, F., Mizusawa, Y., Torchio, M., Alders, M., Giudicessi, J. R., Wilde, A. A. M., Schwartz, P. J., Nerbonne, J. M. & Ackerman, M. J., Aug 1 2014, In : Circulation research. 115, 4, p. 460-469 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Compound heterozygous mutations in the SCN5A-encoded Nav1.5 cardiac sodium channel resulting in atrial standstill and His-Purkinje system disease

Baskar, S., Ackerman, M. J., Clements, D., Mayuga, K. A. & Aziz, P. F., Nov 1 2014, In : Journal of Pediatrics. 165, 5, p. 1050-1052 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

Computer-based early warning system for potentially life-threatening QT prolongation

Bos, J. M., Caraballo, P. J. & Ackerman, M. J., Apr 2014, In : Hospital Medicine Clinics. 3, 2, p. e235-e244

Research output: Contribution to journalReview article

1 Scopus citations

Confirmation of cause and manner of death via a comprehensive cardiac autopsy including whole exome next-generation sequencing

Loporcaro, C. G., Tester, D. J., Maleszewski, J. J., Kruisselbrink, T. & Ackerman, M. J., Aug 2014, In : Archives of Pathology and Laboratory Medicine. 138, 8, p. 1083-1089 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

Congenital long QT syndrome and concomitant early repolarization pattern: A benign association or an ICD-worthy one?

Desimone, C. V. & Ackerman, M. J., Sep 2014, In : Heart rhythm. 11, 9, p. 1639-1640 2 p.

Research output: Contribution to journalEditorial

Deformation patterns in genotyped patients with hypertrophic cardiomyopathy

Geske, J. B., Bos, J. M., Gersh, B. J., Ommen, S. R., Eidem, B. W. & Ackerman, M. J., Apr 2014, In : European heart journal cardiovascular Imaging. 15, 4, p. 456-465 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Device explantation following overdiagnosed and overtreated Jervell and Lange-Nielsen syndrome

Gaba, P., Bos, J. M., Shah, M. J. & Ackerman, M. J., Dec 1 2014, In : Heart rhythm. 11, 12, p. 2310-2313 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Distinguishing hypertrophic cardiomyopathy-associated mutations from background genetic noise

Kapplinger, J. D., Landstrom, A. P., Bos, J. M., Salisbury, B. A., Callis, T. E. & Ackerman, M. J., Apr 2014, In : Journal of cardiovascular translational research. 7, 3, p. 347-361 15 p.

Research output: Contribution to journalArticle

27 Scopus citations

Epilepsy misdiagnosed as long QT syndrome: It can go both ways

Medford, B. A., Bos, J. M. & Ackerman, M. J., Jan 1 2014, In : Congenital Heart Disease. 9, 4, p. E135-E139

Research output: Contribution to journalArticle

7 Scopus citations

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

Arking, D. E., Pulit, S. L., Crotti, L., Van Der Harst, P., Munroe, P. B., Koopmann, T. T., Sotoodehnia, N., Rossin, E. J., Morley, M., Wang, X., Johnson, A. D., Lundby, A., Gudbjartsson, D. F., Noseworthy, P. A., Eijgelsheim, M., Bradford, Y., Tarasov, K. V., Dörr, M., Müller-Nurasyid, M., Lahtinen, A. M. & 210 others, Nolte, I. M., Smith, A. V., Bis, J. C., Isaacs, A., Newhouse, S. J., Evans, D. S., Post, W. S., Waggott, D., Lyytikäinen, L. P., Hicks, A. A., Eisele, L., Ellinghaus, D., Hayward, C., Navarro, P., Ulivi, S., Tanaka, T., Tester, D. J., Chatel, S., Gustafsson, S., Kumari, M., Morris, R. W., Naluai, A. T., Padmanabhan, S., Kluttig, A., Strohmer, B., Panayiotou, A. G., Torres, M., Knoflach, M., Hubacek, J. A., Slowikowski, K., Raychaudhuri, S., Kumar, R. D., Harris, T. B., Launer, L. J., Shuldiner, A. R., Alonso, A., Bader, J. S., Ehret, G., Huang, H., Kao, W. H. L., Strait, J. B., Macfarlane, P. W., Brown, M., Caulfield, M. J., Samani, N. J., Kronenberg, F., Willeit, J., Smith, J. G., Greiser, K. H., Zu Schwabedissen, H. M., Werdan, K., Carella, M., Zelante, L., Heckbert, S. R., Psaty, B. M., Rotter, J. I., Kolcic, I., Polašek, O., Wright, A. F., Griffin, M., Daly, M. J., Arnar, D. O., Hólm, H., Thorsteinsdottir, U., Denny, J. C., Roden, D. M., Zuvich, R. L., Emilsson, V., Plump, A. S., Larson, M. G., O'Donnell, C. J., Yin, X., Bobbo, M., D'Adamo, A. P., Iorio, A., Sinagra, G., Carracedo, A., Cummings, S. R., Nalls, M. A., Jula, A., Kontula, K. K., Marjamaa, A., Oikarinen, L., Perola, M., Porthan, K., Erbel, R., Hoffmann, P., Jöckel, K. H., Kälsch, H., Nöthen, M. M., Den Hoed, M., Loos, R. J. F., Thelle, D. S., Gieger, C., Meitinger, T., Perz, S., Peters, A., Prucha, H., Sinner, M. F., Waldenberger, M., De Boer, R. A., Franke, L., Van Der Vleuten, P. A., Beckmann, B. M., Martens, E., Bardai, A., Hofman, N., Wilde, A. A. M., Behr, E. R., Dalageorgou, C., Giudicessi, J. R., Medeiros-Domingo, A., Barc, J., Kyndt, F., Probst, V., Ghidoni, A., Insolia, R., Hamilton, R. M., Scherer, S. W., Brandimarto, J., Margulies, K., Moravec, C. E., Del Greco M, F., Fuchsberger, C., O'Connell, J. R., Lee, W. K., Watt, G. C. M., Campbell, H., Wild, S. H., El Mokhtari, N. E., Frey, N., Asselbergs, F. W., Leach, I. M., Navis, G., Van Den Berg, M. P., Van Veldhuisen, D. J., Kellis, M., Krijthe, B. P., Franco, O. H., Hofman, A., Kors, J. A., Uitterlinden, A. G., Witteman, J. C. M., Kedenko, L., Lamina, C., Oostra, B. A., Abecasis, G. R., Lakatta, E. G., Mulas, A., Orrú, M., Schlessinger, D., Uda, M., Markus, M. R. P., Völker, U., Snieder, H., Spector, T. D., Ärnlöv, J., Lind, L., Sundström, J., Syvänen, A. C., Kivimaki, M., Kähönen, M., Mononen, N., Raitakari, O. T., Viikari, J. S., Adamkova, V., Kiechl, S., Brion, M., Nicolaides, A. N., Paulweber, B., Haerting, J., Dominiczak, A. F., Nyberg, F., Whincup, P. H., Hingorani, A. D., Schott, J. J., Bezzina, C. R., Ingelsson, E., Ferrucci, L., Gasparini, P., Wilson, J. F., Rudan, I., Franke, A., Mühleisen, T. W., Pramstaller, P. P., Lehtimäki, T. J., Paterson, A. D., Parsa, A., Liu, Y., Van Duijn, C. M., Siscovick, D. S., Gudnason, V., Jamshidi, Y., Salomaa, V., Felix, S. B., Sanna, S., Ritchie, M. D., Stricker, B. H., Stefansson, K., Boyer, L. A., Cappola, T. P., Olsen, J. V., Lage, K., Schwartz, P. J., Kääb, S., Chakravarti, A., Ackerman, M. J., Pfeufer, A., De Bakker, P. I. W. & Newton-Cheh, C., Aug 2014, In : Nature Genetics. 46, 8, p. 826-836 11 p.

Research output: Contribution to journalArticle

130 Scopus citations

Genetics of long QT syndrome

Tester, D. J. & Ackerman, M. J., Jan 1 2014, In : Methodist DeBakey cardiovascular journal. 10, 1, p. 29-33 5 p.

Research output: Contribution to journalReview article

64 Scopus citations

Heart-Rate-Corrected QT Interval Evolution in Premature Infants During the First Week of Life

Ulrich, T. J. B., Ellsworth, M. A., Carey, W. A., Zubair, A. S., MacQueen, B. C., Colby, C. E. & Ackerman, M. J., 2014, In : Pediatric Cardiology. 35, 8, p. 1363-1369 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Impact of left ventricular hypertrophy on QT prolongation and associated mortality

Haugaa, K. H., Bos, J. M., Borkenhagen, E. J., Tarrell, R. F., Morlan, B. W., Caraballo, P. & Ackerman, M. J., Nov 1 2014, In : Heart Rhythm. 11, 11, p. 1957-1965 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Is sudden unexplained nocturnal death syndrome in Southern China a cardiac sodium channel dysfunction disorder?

Liu, C., Tester, D. J., Hou, Y., Wang, W., Lv, G., Ackerman, M. J., Makielski, J. C. & Cheng, J., Mar 1 2014, In : Forensic Science International. 236, p. 38-45 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Loss-of-function of the voltage-gated sodium channel NaV1.5 (Channelopathies) in patients with irritable bowel syndrome

Beyder, A., Mazzone, A., Strege, P. R., Tester, D. J., Saito, Y. A., Bernard, C. E., Enders, F. T., Ek, W. E., Schmidt, P. T., Dlugosz, A., Lindberg, G., Karling, P., Ohlsson, B., Gazouli, M., Nardone, G., Cuomo, R., Usai-Satta, P., Galeazzi, F., Neri, M., Portincasa, P. & 8 others, Bellini, M., Barbara, G., Camilleri, M., Locke, G. R., Talley, N. J., D'Amato, M., Ackerman, M. J. & Farrugia, G., Jun 2014, In : Gastroenterology. 146, 7, p. 1659-1668 10 p.

Research output: Contribution to journalArticle

65 Scopus citations

Pathogeneses of sudden cardiac death in national collegiate athletic association athletes

Harmon, K. G., Drezner, J. A., Maleszewski, J. J., Lopez-Anderson, M., Owens, D., Prutkin, J. M., Asif, I. M., Klossner, D. & Ackerman, M. J., Apr 2014, In : Circulation: Arrhythmia and Electrophysiology. 7, 2, p. 198-204 7 p.

Research output: Contribution to journalArticle

83 Scopus citations

Prevalence and spectrum of electroencephalogram-identified epileptiform activity among patients with long QT syndrome

Anderson, J. H., Bos, J. M., Cascino, G. D. & Ackerman, M. J., Jan 1 2014, In : Heart rhythm. 11, 1, p. 53-57 5 p.

Research output: Contribution to journalArticle

41 Scopus citations

Rationale and objectives for ECG screening in infancy

Saul, J. P., Schwartz, P. J., Ackerman, M. J. & Triedman, J. K., Dec 1 2014, In : Heart rhythm. 11, 12, p. 2316-2321 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Reduced junctional Na+/Ca2+-exchanger activity contributes to sarcoplasmic reticulum Ca2+ leak in junctophilin-2-deficient mice

Wang, W., Landstrom, A. P., Wang, Q., Munro, M. L., Beavers, D., Ackerman, M. J., Soeller, C. & Wehrens, X. H. T., Nov 1 2014, In : American Journal of Physiology - Heart and Circulatory Physiology. 307, 9, p. H1317-H1326

Research output: Contribution to journalArticle

19 Scopus citations

Response to letters regarding article, "stroke or transient ischemic attack in patients with transvenous pacemaker or defibrillator and echocardiographically detected patent foramen ovale"

DeSimone, C. V., Friedman, P. A., Noheria, A., Ackerman, M. J., Asirvatham, S. J., DeSimone, D. C., Aakre, C. A. & Vaidya, V. R., Jul 8 2014, In : Circulation. 130, 2, p. e13-e14

Research output: Contribution to journalLetter

1 Scopus citations
4 Scopus citations

Surgical myectomy improves pulmonary hypertension in obstructive hypertrophic cardiomyopathy

Geske, J. B., Konecny, T., Ommen, S. R., Nishimura, R. A., Sorajja, P., Schaff, H. V., Ackerman, M. J. & Gersh, B. J., Aug 7 2014, In : European heart journal. 35, 30, p. 2032-2039 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Sympathetic nerve activity and simulated diving in healthy humans

Shamsuzzaman, A., Ackerman, M. J., Kuniyoshi, F. S., Accurso, V., Davison, D., Amin, R. S. & Somers, V. K., Jan 1 2014, In : Autonomic Neuroscience: Basic and Clinical. 181, 1, p. 74-78 5 p.

Research output: Contribution to journalArticle

18 Scopus citations
2013

Abnormal electrocardiographic findings in athletes: Recognising changes suggestive of primary electrical disease

Drezner, J. A., Ackerman, M. J., Cannon, B. C., Corrado, D., Heidbuchel, H., Prutkin, J. M., Salerno, J. C., Anderson, J., Ashley, E., Asplund, C. A., Baggish, A. L., Börjesson, M., DiFiori, J. P., Fischbach, P., Froelicher, V., Harmon, K. G., Marek, J., Owens, D. S., Paul, S., Pelliccia, A. & 5 others, Schmied, C. M., Sharma, S., Stein, R., Vetter, V. L. & Wilson, M. G., Feb 2013, In : British journal of sports medicine. 47, 3, p. 153-167 15 p.

Research output: Contribution to journalArticle

87 Scopus citations

Abnormal electrocardiographic findings in athletes: Recognising changes suggestive of cardiomyopathy

Drezner, J. A., Ashley, E., Baggish, A. L., Börjesson, M., Corrado, D., Owens, D. S., Patel, A., Pelliccia, A., Vetter, V. L., Ackerman, M. J., Anderson, J., Asplund, C. A., Cannon, B. C., DiFiori, J., Fischbach, P., Froelicher, V., Harmon, K. G., Heidbuchel, H., Marek, J., Paul, S. & 6 others, Prutkin, J. M., Salerno, J. C., Schmied, C. M., Sharma, S., Stein, R. & Wilson, M., Feb 2013, In : British journal of sports medicine. 47, 3, p. 137-152 16 p.

Research output: Contribution to journalArticle

103 Scopus citations

A KCNQ1 mutation causes a high penetrance for familial atrial fibrillation

Bartos, D. C., Anderson, J. B., Bastiaenen, R., Johnson, J. N., Gollob, M. H., Tester, D. J., Burgess, D. E., Homfray, T., Behr, E. R., Ackerman, M. J., Guicheney, P. & Delisle, B. P., May 2013, In : Journal of cardiovascular electrophysiology. 24, 5, p. 562-569 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Arrhythmia phenotype during fetal life suggests long-QT syndrome genotype: Risk stratification of perinatal long-QT syndrome

Cuneo, B. F., Etheridge, S. P., Horigome, H., Sallee, D., Moon-Grady, A., Weng, H. Y., Ackerman, M. J. & Woodrow Benson, D., Oct 1 2013, In : Circulation: Arrhythmia and Electrophysiology. 6, 5, p. 946-951 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Arrhythmia risk in long QT syndrome: Beyond the disease-causative mutation

Giudicessi, J. R. & Ackerman, M. J., Aug 1 2013, In : Circulation: Cardiovascular Genetics. 6, 4, p. 313-316 4 p.

Research output: Contribution to journalReview article

9 Scopus citations

Arrhythmias and arrhythmia management in hypertrophic cardiomyopathy

Bos, J. M., Ommen, S. R. & Ackerman, M. J., Jul 1 2013, Electrical Diseases of the Heart. Springer-Verlag London Ltd, Vol. 2. p. 7-24 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Arrhythmias and arrhythmia management in hypertrophic cardiomyopathy

Martijn Bos, J., Ommen, S. R. & Ackerman, M. J., Jan 1 2013, Electrical Diseases of the Heart: Volume 2: Diagnosis and Treatment, Second Edition. Springer-Verlag London Ltd, p. 7-24 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter