Michael John Ackerman, MD, PhD, FACC

  • 37105 Citations
  • 106 Scopus h-Index
1991 …2020

Research output per year

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Research Output

2002

Epinephrine-induced QT interval prolongation: A gene-specific paradoxical response in congenital long QT syndrome

Ackerman, M. J., Khositseth, A., Tester, D. J., Hejlik, J. B., Shen, W. K. & Porter, C. B. J., Jan 1 2002, In : Mayo Clinic proceedings. 77, 5, p. 413-421 9 p., 62209.

Research output: Contribution to journalArticle

162 Scopus citations

Interaction with GM130 during HERG ion channel trafficking: Disruption by type 2 congenital long QT syndrome mutations

Roti Roti, E. C., Myers, C. D., Ayers, R. A., Boatman, D. E., Delfosse, S. A., Chan, E. K. L., Ackerman, M. J., January, C. T. & Robertson, G. A., Dec 6 2002, In : Journal of Biological Chemistry. 277, 49, p. 47779-47785 7 p.

Research output: Contribution to journalArticle

61 Scopus citations

Prevalence and age-dependence of malignant mutations in the beta-myosin heavy chain and troponin T genes in hypertrophic cardiomyopathy: A comprehensive outpatient perspective

Ackerman, M. J., VanDriest, S. L., Ommen, S. R., Will, M. L., Nishimura, R. A., Tajik, A. J. & Gersh, B. J., Jun 19 2002, In : Journal of the American College of Cardiology. 39, 12, p. 2042-2048 7 p.

Research output: Contribution to journalArticle

198 Scopus citations

Prevalence and severity of "benign" mutations in the β-myosin heavy chain, cardiac troponin T, and α-tropomyosin genes in hypertrophic cardiomyopathy

Van Driest, S. L., Ackerman, M. J., Ommen, S. R., Shakur, R., Will, M. L., Nishimura, R. A., Tajik, A. J. & Gersh, B. J., Dec 10 2002, In : Circulation. 106, 24, p. 3085-3090 6 p.

Research output: Contribution to journalArticle

151 Scopus citations

Role of transvenous implantable cardioverter-defibrillators in preventing sudden cardiac death in children, adolescents, and young adults

Chatrath, R., Porter, C. B. J. & Ackerman, M. J., Jan 1 2002, In : Mayo Clinic proceedings. 77, 3, p. 226-231 6 p., 62353.

Research output: Contribution to journalArticle

66 Scopus citations

SCN5A is expressed in human jejunal circular smooth muscle cells

Ou, Y., Gibbons, S. J., Miller, S. M., Strege, P. R., Rich, A., Distad, M. A., Ackerman, M. J., Rae, J. L., Szurszewski, J. H. & Farrugia, G., Nov 6 2002, In : Neurogastroenterology and Motility. 14, 5, p. 477-486 10 p.

Research output: Contribution to journalArticle

59 Scopus citations

Sex-selective QT prolongation during rapid eye movement sleep

Lanfranchi, P. A., Shamsuzzaman, A. S. M., Ackerman, M. J., Kara, T., Jurak, P., Wolk, R. & Somers, V. K., Sep 17 2002, In : Circulation. 106, 12, p. 1488-1492 5 p.

Research output: Contribution to journalArticle

36 Scopus citations
2001

Cardiac sodium channel gene mutations and sudden infant death syndrome: Confirmation of proof of concept?

Towbin, J. A. & Ackerman, M. J., Sep 4 2001, In : Circulation. 104, 10, p. 1092-1093 2 p.

Research output: Contribution to journalEditorial

12 Scopus citations

Diagnostic accuracy of screening electrocardiograms in long QT syndrome I

Miller, M. D., Porter, C. B. J. & Ackerman, M. J., Jul 11 2001, In : Pediatrics. 108, 1, p. 8-12 5 p.

Research output: Contribution to journalArticle

38 Scopus citations

Molecular autopsy of sudden unexplained death in the young

Ackerman, M. J., Tester, D. J. & Driscoll, D. J., Jun 11 2001, In : American Journal of Forensic Medicine and Pathology. 22, 2, p. 105-111 7 p.

Research output: Contribution to journalArticle

108 Scopus citations

Postmortem molecular analysis of SCN5A defects in sudden infant death syndrome

Ackerman, M. J., Siu, B. L., Sturner, W. Q., Tester, D. J., Valdivia, C. R., Makielski, J. C. & Towbin, J. A., Nov 14 2001, In : Journal of the American Medical Association. 286, 18, p. 2264-2269 6 p.

Research output: Contribution to journalArticle

Open Access
381 Scopus citations

Pulmonary atresia with ventricular septal defect and persistent airway hyperresponsiveness

Ackerman, M. J., Wylam, M. E., Feldt, R. H., Porter, C. B. J., Dewald, G., Scanlon, P. D. & Driscoll, D. J., Jul 1 2001, In : Journal of Thoracic and Cardiovascular Surgery. 122, 1, p. 169-177 9 p.

Research output: Contribution to journalArticle

19 Scopus citations
2000

Inherited and de novo mutations in the cardiac actin gene cause hypertrophic cardiomyopathy

Olson, T. M., Doan, T. P., Kishimoto, N. Y., Whitby, F. G., Ackerman, M. J. & Fananapazir, L., Jan 1 2000, In : Journal of Molecular and Cellular Cardiology. 32, 9, p. 1687-1694 8 p.

Research output: Contribution to journalArticle

166 Scopus citations

The long-QT syndrome [2] (multiple letters)

Allan, W. C., Ackerman, M. J. & Porter, C. B. J., Feb 17 2000, In : New England Journal of Medicine. 342, 7, p. 514-515 2 p.

Research output: Contribution to journalLetter

1 Scopus citations
1999

Molecular diagnosis of the inherited long-QT syndrome in a woman who died after near-drowning

Ackerman, M. J., Tester, D. J., Porter, C. B. J. & Edwards, W. D., Oct 7 1999, In : New England Journal of Medicine. 341, 15, p. 1121-1125 5 p.

Research output: Contribution to journalArticle

110 Scopus citations

Swimming, a gene-specific arrhythmogenic trigger for inherited long QT syndrome

Ackerman, M. J., Tester, D. J. & Porter, B. J., Jan 1 1999, In : Mayo Clinic proceedings. 74, 11, p. 1088-1094 7 p.

Research output: Contribution to journalArticle

196 Scopus citations
1998

A novel mutation in KVLQT1 is the molecular basis of inherited long QT syndrome in a near-drowning patient's family

Ackerman, M. J., Schroeder, J. J., Berry, R., Schaid, D. J., Porter, C. B. J., Michels, V. V. & Thibodeau, S. N., Aug 1998, In : Pediatric Research. 44, 2, p. 148-153 6 p.

Research output: Contribution to journalArticle

Open Access
41 Scopus citations

Identification of a family with inherited long QT syndrome after a pediatric near-drowning

Ackerman, M. J. & Porter, C. B. J., Feb 1998, In : Pediatrics. 101, 2, p. 306-308 3 p.

Research output: Contribution to journalArticle

26 Scopus citations

Long QT syndrome [1] (multiple letters)

Allan, W. C., Ackerman, M. J. & Porter, C. B. J., Jan 1 1998, In : Pediatrics. 102, 5, p. 1220-1221 2 p.

Research output: Contribution to journalLetter

3 Scopus citations

The long QT syndrome: Ion channel diseases of the heart

Ackerman, M. J., Jan 1 1998, In : Mayo Clinic proceedings. 73, 3, p. 250-269 20 p.

Research output: Contribution to journalReview article

Open Access
251 Scopus citations

The long QT syndrome.

Ackerman, M. J., Jul 1998, In : Pediatrics in review / American Academy of Pediatrics. 19, 7, p. 232-238 7 p.

Research output: Contribution to journalReview article

38 Scopus citations
1997

Mechanisms of disease: Ion channels - Basic science and clinical disease

Ackerman, M. J. & Clapham, D. E., Jun 14 1997, In : New England Journal of Medicine. 336, 22, p. 1575-1586 12 p.

Research output: Contribution to journalReview article

286 Scopus citations
1994

Characterization of a native swelling-induced chloride current, ICl.swell, and its regulatory protein, pICln, in Xenopus oocytes.

Ackerman, M. J., Krapivinsky, G. B., Gordon, E., Krapivinsky, L. & Clapham, D. C., 1994, In : The Japanese journal of physiology. 44 Suppl 2, p. S17-24

Research output: Contribution to journalArticle

14 Scopus citations

Hypotonicity activates a native chloride current in Xenopus oocytes

Ackerman, M. J., Wickman, K. D. & Clapham, D. E., Feb 1 1994, In : Journal of General Physiology. 103, 2, p. 153-179 27 p.

Research output: Contribution to journalArticle

Open Access
201 Scopus citations

Molecular characterization of a swelling-induced chloride conductance regulatory protein, plCIn

Krapivinsky, G. B., Ackerman, M. J., Gordon, E. A., Krapivinsky, L. D. & Clapham, D. E., Feb 11 1994, In : Cell. 76, 3, p. 439-448 10 p.

Research output: Contribution to journalArticle

182 Scopus citations
1993

Cardiac chloride channels

Ackerman, M. J. & Clapham, D. E., Jan 1 1993, In : Trends in cardiovascular medicine. 3, 1, p. 23-28 6 p.

Research output: Contribution to journalShort survey

52 Scopus citations
1992

New mammalian chloride channel identified by expression cloning

Paulmichl, M., Li, Y., Wickman, K., Ackerman, M., Peralta, E. & Clapham, D., Jan 1 1992, In : Nature. 356, 6366, p. 238-241 4 p.

Research output: Contribution to journalArticle

297 Scopus citations
1991

Two novel cardiac atrial K+ channels, IK.AA and IK.PC

Wallert, M. A., Ackerman, M. J., Kim, D. & Clapham, D. E., Nov 1 1991, In : Journal of General Physiology. 98, 5, p. 921-939 19 p.

Research output: Contribution to journalArticle

Open Access
25 Scopus citations