Michael John Ackerman, MD, PhD, FACC

  • 37462 Citations
  • 106 Scopus h-Index
1991 …2020

Research output per year

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Research Output

2005

Molecular autopsy vs postmortem genetic testing [3] (multiple letters)

Edwards, W. D. & Ackerman, M. J., Sep 2005, In : Mayo Clinic proceedings. 80, 9, p. 1234-1235 2 p.

Research output: Contribution to journalLetter

Open Access
2 Scopus citations

Pathogenesis of unexplained drowning: New insights from a molecular autopsy

Tester, D. J., Kopplin, L. J., Creighton, W., Burke, A. P. & Ackerman, M. J., May 2005, In : Mayo Clinic proceedings. 80, 5, p. 596-600 5 p.

Research output: Contribution to journalArticle

64 Scopus citations

Sarcomeric genotyping in hypertrophic cardiomyopathy

Van Driest, S. L., Ommen, S. R., Tajik, A. J., Gersh, B. J. & Ackerman, M. J., Apr 2005, In : Mayo Clinic proceedings. 80, 4, p. 463-469 7 p.

Research output: Contribution to journalArticle

128 Scopus citations

Spectrum and prevalence of cardiac ryanodine receptor (RyR2) mutations in a cohort of unrelated patients referred explicitly for long QT syndrome genetic testing

Tester, D. J., Kopplin, L. J., Will, M. L. & Ackerman, M. J., Oct 1 2005, In : Heart rhythm. 2, 10, p. 1099-1105 7 p.

Research output: Contribution to journalArticle

111 Scopus citations

Standard mutation nomenclature in hypertrophic cardiomyopathy: An urgent need [2] (multiple letters)

Hermida-Prieto, M., Laredo, R., Monserrat, L., Castro-Beiras, A., Van Driest, S. L., Vasile, V. C., Ommen, S. R., Will, M. L., Tajik, A. J., Gersh, B. J. & Ackerman, M. J., Jul 19 2005, In : Journal of the American College of Cardiology. 46, 2, p. 380-381 2 p.

Research output: Contribution to journalLetter

Sudden infant death syndrome: How significant are the cardiac channelopathies?

Tester, D. J. & Ackerman, M. J., Aug 15 2005, In : Cardiovascular research. 67, 3, p. 388-396 9 p.

Research output: Contribution to journalReview article

151 Scopus citations

Targeted mutational analysis of ankyrin-B in 541 consecutive, unrelated patients referred for long QT syndrome genetic testing and 200 healthy subjects

Sherman, J., Tester, D. J. & Ackerman, M. J., Nov 1 2005, In : Heart rhythm. 2, 11, p. 1218-1223 6 p.

Research output: Contribution to journalArticle

40 Scopus citations

Task force 4: HCM and other cardiomyopathies, mitral valve prolapse, myocarditis, and Marfan syndrome

Maron, B. J., Ackerman, M. J., Nishimura, R. A., Pyeritz, R. E., Towbin, J. A. & Udelson, J. E., Apr 19 2005, In : Journal of the American College of Cardiology. 45, 8, p. 1340-1345 6 p.

Research output: Contribution to journalArticle

202 Scopus citations

Task force 7: Arrhythmias

Zipes, D. P., Ackerman, M. J., Estes, N. A. M., Grant, A. O., Myerburg, R. J. & Van Hare, G., Apr 19 2005, In : Journal of the American College of Cardiology. 45, 8, p. 1354-1363 10 p.

Research output: Contribution to journalArticle

157 Scopus citations

The changing face of sudden cardiac death in the young

Ellsworth, E. G. & Ackerman, M. J., Dec 1 2005, In : Heart rhythm. 2, 12, p. 1283-1285 3 p.

Research output: Contribution to journalEditorial

22 Scopus citations

Volatile anesthetics and the long QT syndrome [6] (multiple letters)

Rasche, S., Hübler, M., Kies, S. J., Pabelick, C. M., Hurley, H. A., White, R. D. & Ackerman, M. J., Dec 2005, In : Anesthesiology. 103, 6, p. 1316-1317 2 p.

Research output: Contribution to journalLetter

3 Scopus citations

Yield of genetic testing in hypertrophic cardiomyopathy

Van Driest, S. L., Ommen, S. R., Tajik, A. J., Gersh, B. J. & Ackerman, M. J., Jun 2005, In : Mayo Clinic proceedings. 80, 6, p. 739-744 6 p.

Research output: Contribution to journalArticle

127 Scopus citations
2004

A trafficking defective, Brugada syndrome-causing SCN5A mutation rescued by drugs

Valdivia, C. R., Tester, D. J., Rok, B. A., Porter, C. B. J., Munger, T. M., Jahangir, A., Makielski, J. C. & Ackerman, M. J., Apr 1 2004, In : Cardiovascular research. 62, 1, p. 53-62 10 p.

Research output: Contribution to journalArticle

103 Scopus citations

Cardiac channelopathies: It's in the genes

Ackerman, M. J., May 1 2004, In : Nature Medicine. 10, 5, p. 463-464 2 p.

Research output: Contribution to journalShort survey

130 Scopus citations

Characterization of a KCNQ1/KVLQT1 polymorphism in Asian families with LQT2: Implications for genetic testing

Sharma, D., Glatter, K. A., Timofeyev, V., Tuteja, D., Zhang, Z., Rodriguez, J., Tester, D. J., Low, R., Scheinman, M. M., Ackerman, M. J. & Chiamvimonvat, N., Jul 1 2004, In : Journal of Molecular and Cellular Cardiology. 37, 1, p. 79-89 11 p.

Research output: Contribution to journalArticle

31 Scopus citations

Comprehensive analysis of the beta-myosin heavy chain gene in 389 unrelated patients with hypertrophic cardiomyopathy

Van Driest, S. L., Jaeger, M. A., Ommen, S. R., Will, M. L., Gersh, B. J., Tajik, A. J. & Ackerman, M. J., Aug 4 2004, In : Journal of the American College of Cardiology. 44, 3, p. 602-610 9 p.

Research output: Contribution to journalArticle

149 Scopus citations

Excitability and Conduction

Ackerman, M. J. & Clapham, D. E., Mar 19 2004, Molecular Basis of Cardiovascular Disease: A Companion to Braunwald's Heart Disease. Elsevier Inc., p. 311-335 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

From malignant mutations to malignant domains: The continuing search for prognostic significance in the mutant genes causing hypertrophic cardiomyopathy

Van Driest, S. L., Maron, B. J. & Ackerman, M. J., Jan 2004, In : Heart. 90, 1, p. 7-8 2 p.

Research output: Contribution to journalEditorial

Open Access
35 Scopus citations

Heart rate dependence of the QT interval duration: Differences among congenital long QT syndrome subtypes

Němec, J., Buncová, M., Bůlková, V., Hejlik, J., Winter, B., Shen, W. K. & Ackerman, M. J., May 2004, In : Journal of cardiovascular electrophysiology. 15, 5, p. 550-556 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Identification of a common genetic substrate underlying postpartum cardiac events in congenital long QT syndrome

Khositseth, A., Tester, D. J., Will, M. L., Bell, C. M. & Ackerman, M. J., May 2004, In : Heart rhythm. 1, 1, p. 60-64 5 p.

Research output: Contribution to journalArticle

83 Scopus citations

Intracellular signaling and regulation of cardiac ion channels

Khositseth, A., Clapham, D. E. & Ackerman, M. J., Jan 1 2004, Cardiac Electrophysiology: From Cell to Bedside. Elsevier Inc., p. 33-41 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

13 Scopus citations

Molecular and functional characterization of common polymorphisms in HERG (KCNH2) potassium channels

Anson, B. D., Ackerman, M. J., Tester, D. J., Will, M. L., Delisle, B. P., Anderson, C. L. & January, C. T., Jun 1 2004, In : American Journal of Physiology - Heart and Circulatory Physiology. 286, 6 55-6, p. H2434-H2441

Research output: Contribution to journalArticle

110 Scopus citations

Molecular basis of congenital and acquired long QT syndromes

Ackerman, M. J., Oct 1 2004, In : Journal of Electrocardiology. 37, SUPPL., p. 1-6 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

My child just fainted: no big deal or sudden-death warning?

Tipton, M. L. & Ackerman, M. J., Jul 2004, In : Emergency medical services. 33, 7, p. 41-45 5 p.

Research output: Contribution to journalArticle

Myosin binding protein C mutations and compound heterozygosity in hypertrophic cardiomyopathy

Van Driest, S. L., Vasile, V. C., Ommen, S. R., Will, M. L., Tajik, A. J., Gersh, B. J. & Ackerman, M. J., Nov 2 2004, In : Journal of the American College of Cardiology. 44, 9, p. 1903-1910 8 p.

Research output: Contribution to journalArticle

314 Scopus citations

Prenatal molecular genetic diagnosis of congenital long QT syndrome by strategic genotyping

Tester, D. J., McCormack, J. & Ackerman, M. J., Mar 15 2004, In : American Journal of Cardiology. 93, 6, p. 788-791 4 p.

Research output: Contribution to journalArticle

20 Scopus citations

Recommendations for physical activity and recreational sports participation for young patients with genetic cardiovascular diseases

Maron, B. J., Chaitman, B. R., Ackerman, M. J., De Luna, A. B., Corrado, D., Crosson, J. E., Deal, B. J., Driscoll, D. J., Estes, N. A. M., Araújo, C. G. S., Liang, D. H., Mitten, M. J., Myerburg, R. J., Pelliccia, A., Thompson, P. D., Towbin, J. A. & Van Camp, S. P., Jun 8 2004, In : Circulation. 109, 22, p. 2807-2816 10 p.

Research output: Contribution to journalArticle

430 Scopus citations

Spectrum and frequency of cardiac channel defects in swimming-triggered arrhythmia syndromes

Choi, G., Kopplin, L. J., Tester, D. J., Will, M. L., Haglund, C. M. & Ackerman, M. J., Oct 12 2004, In : Circulation. 110, 15, p. 2119-2124 6 p.

Research output: Contribution to journalArticle

186 Scopus citations

Spectrum and prevalence of cardiac sodium channel variants among black, white, Asian, and Hispanic individuals: Implications for arrhythmogenic susceptibility and Brugada/long QT syndrome genetic testing

Ackerman, M. J., Splawski, I., Makielski, J. C., Tester, D. J., Will, M. L., Timothy, K. W., Keating, M. T., Jones, G., Chadha, M., Burrow, C. R., Stephens, J. C., Xu, C., Judson, R. & Curran, M. E., Nov 2004, In : Heart rhythm. 1, 5, p. 600-607 8 p.

Research output: Contribution to journalArticle

231 Scopus citations

Sudden cardiac death and channelopathies: A review of implantable defibrillator therapy

Choi, G. R., Porter, C. B. J. & Ackerman, M. J., Oct 1 2004, In : Pediatric Clinics of North America. 51, 5, p. 1289-1303 15 p.

Research output: Contribution to journalReview article

16 Scopus citations

Targeted mutational analysis of the RyR2-encoded cardiac ryanodine receptor in sudden unexplained death: A molecular autopsy of 49 medical examiner/coroner's cases

Tester, D. J., Spoon, D. B., Valdivia, H. H., Makielski, J. C. & Ackerman, M. J., Nov 2004, In : Mayo Clinic proceedings. 79, 11, p. 1380-1384 5 p.

Research output: Contribution to journalArticle

210 Scopus citations

β-blocker therapy failures in symptomatic probands with genotyped long-QT syndrome

Chatrath, R., Bell, C. M. & Ackerman, M. J., Sep 1 2004, In : Pediatric Cardiology. 25, 5, p. 459-465 7 p.

Research output: Contribution to journalArticle

57 Scopus citations
2003

A common human SCN5A polymorphism modifies expression of an arrhythmia causing mutation

Ye, B., Valdivia, C. R., Ackerman, M. J. & Makielski, J. C., Apr 2003, In : Physiological Genomics. 12, p. 187-193 7 p.

Research output: Contribution to journalArticle

142 Scopus citations

A Ubiquitous Splice Variant and a Common Polymorphism Affect Heterologous Expression of Recombinant Human SCN5A Heart Sodium Channels

Makielski, J. C., Ye, B., Valdivia, C. R., Pagel, M. D., Pu, J., Tester, D. J. & Ackerman, M. J., Oct 31 2003, In : Circulation research. 93, 9, p. 821-828 8 p.

Research output: Contribution to journalArticle

183 Scopus citations

Catecholamine-induced T-wave lability in congenital long QT syndrome: A novel phenomenon associated with syncope and cardiac arrest

Nemec, J., Hejlik, J. B., Shen, W. K. & Ackerman, M. J., Jan 1 2003, In : Mayo Clinic proceedings. 78, 1, p. 40-50 11 p.

Research output: Contribution to journalArticle

47 Scopus citations

Catecholamine-provoked microvoltage T wave alternans in genotyped long QT syndrome

Nemec, J., Ackerman, M. J., Tester, D. J., Hejlik, J. & Shen, W. K., Aug 1 2003, In : PACE - Pacing and Clinical Electrophysiology. 26, 8, p. 1660-1667 8 p.

Research output: Contribution to journalArticle

22 Scopus citations
6 Scopus citations

Effect of phenylephrine provocation on dispersion of repolarization in congenital long QT syndrome

Khositseth, A., Nemec, J., Hejlik, J., Shen, W. K. & Ackerman, M. J., Jul 1 2003, In : Annals of Noninvasive Electrocardiology. 8, 3, p. 208-214 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Ethnic Differences in Cardiac Potassium Channel Variants: Implications for Genetic Susceptibility to Sudden Cardiac Death and Genetic Testing for Congenital Long QT Syndrome

Ackerman, M. J., Tester, D. J., Jones, G. S., Will, M. L., Burrow, C. R. & Curran, M. E., Dec 2003, In : Mayo Clinic proceedings. 78, 12, p. 1479-1487 9 p.

Research output: Contribution to journalArticle

249 Scopus citations
6 Scopus citations

Prevalence and spectrum of thin filament mutations in an outpatient referral population with hypertrophic cardiomyopathy

Van Driest, S. L., Ellsworth, E. G., Ommen, S. R., Tajik, A. J., Gersh, B. J. & Ackerman, M. J., Jul 29 2003, In : Circulation. 108, 4, p. 445-451 7 p.

Research output: Contribution to journalArticle

170 Scopus citations

Primer on medical genomics part VI: Genomics and molecular genetics in clinical practice

Ansell, S. M., Ackerman, M. J., Black, J. L., Roberts, L. R. & Tefferi, A., Mar 1 2003, In : Mayo Clinic proceedings. 78, 3, p. 307-317 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Primer on medical genomics part VIII: Essentials of medical genetics for the practicing physician

Ensenauer, R. E., Reinke, S. S., Ackerman, M. J., Tester, D. J., Whiteman, D. A. H. & Tefferi, A., Jul 1 2003, In : Mayo Clinic proceedings. 78, 7, p. 846-857 12 p.

Research output: Contribution to journalReview article

14 Scopus citations

Sudden unexplained death: Evaluation of those left behind

Lee, A. & Ackerman, M. J., Nov 1 2003, In : Lancet. 362, 9394, p. 1429-1431 3 p.

Research output: Contribution to journalComment/debate

11 Scopus citations

Sympathetic nerve activity in the congenital long-QT syndrome

Shamsuzzaman, A. S. M., Ackerman, M. J., Kara, T., Lanfranchi, P. & Somers, V. K., Apr 15 2003, In : Circulation. 107, 14, p. 1844-1847 4 p.

Research output: Contribution to journalArticle

16 Scopus citations

Syncope in children and adolescents and the congenital long QT syndrome

Khositseth, A., Martinez, M. W., Driscoll, D. J. & Ackerman, M. J., Sep 15 2003, In : American Journal of Cardiology. 92, 6, p. 746-749 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Syntrophin γ2 regulates SCN5A gating by a PDZ domain-mediated interaction

Ou, Y., Strege, P., Miller, S. M., Makielski, J., Ackerman, M., Gibbons, S. J. & Farrugia, G., Jan 17 2003, In : Journal of Biological Chemistry. 278, 3, p. 1915-1923 9 p.

Research output: Contribution to journalArticle

91 Scopus citations
2002

A novel SCN5A arrhythmia mutation, M1766L, with expression defect rescued by mexiletine

Valdivia, C. R., Ackerman, M. J., Tester, D. J., Wada, T., McCormack, J., Ye, B. & Makielski, J. C., Jul 25 2002, In : Cardiovascular research. 55, 2, p. 279-289 11 p.

Research output: Contribution to journalArticle

75 Scopus citations

A novel TPM1 mutation in a family with hypertrophic cardiomyopathy and sudden cardiac death in childhood

Van Driest, S. L., Will, M. L., Atkins, D. L. & Ackerman, M. J., Nov 15 2002, In : American Journal of Cardiology. 90, 10, p. 1123-1127 5 p.

Research output: Contribution to journalArticle

28 Scopus citations