• 9976 Citations
  • 47 Scopus h-Index
1990 …2020
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1990 2019

Filter
Article
2019
2 Citations (Scopus)

Cloning, function, and localization of human, canine, and Drosophila ZIP10 (SLC39A10), a Zn2+ transporter

Landry, G. M., Furrow, E., Holmes, H. L., Hirata, T., Kato, A., Williams, P., Strohmaier, K., Gallo, C. J. R., Chang, M., Pandey, M., Jiang, H., Bansal, A., Franz, M. C., Montalbetti, N., Alexander, M. P., Cabrero, P., Dow, J. A. T., DeGrado, T. R. & Romero, M. F., Feb 1 2019, In : American journal of physiology. Renal physiology. 316, 2, p. F263-F273

Research output: Contribution to journalArticle

Drosophila
Canidae
Organism Cloning
Kidney
Malpighian Tubules

Regulation of renal naDC1 expression and citrate excretion by NBCe1-a

Osis, G., Webster, K. L., Harris, A. N., Lee, H. W., Chen, C., Fang, L., Romero, M. F., Khattri, R. B., Merritt, M. E., Verlander, J. W. & Weiner, I. D., Aug 2019, In : American Journal of Physiology - Renal Physiology. 317, 2, p. F489-F501

Research output: Contribution to journalArticle

Citric Acid
Kidney
Hypokalemia
Acidosis
Acids

Targeted renal knockdown of Na+/H+ exchanger regulatory factor Sip1 produces uric acid nephrolithiasis in Drosophila

Ghimire, S., Terhzaz, S., Cabrero, P., Romero, M. F., Davies, S. A. & Dow, J. A. T., Oct 1 2019, In : American journal of physiology. Renal physiology. 317, 4, p. F930-F940

Research output: Contribution to journalArticle

Nephrolithiasis
Uric Acid
Drosophila
Kidney
Sodium-Hydrogen Antiporter
2018
4 Citations (Scopus)

Expression of the B splice variant of NBCe1 (SLC4A4) in the mouse kidney

Fang, L., Lee, H. W., Chen, C., Harris, A. N., Romero, M. F., Verlander, J. W. & Weiner, I. D., Sep 1 2018, In : American Journal of Physiology - Renal Physiology. 315, 3, p. F417-F428

Research output: Contribution to journalArticle

Sodium-Bicarbonate Symporters
Kidney
Messenger RNA
Acids
Antibodies
6 Citations (Scopus)

Geobiology reveals how human kidney stones dissolve in vivo

Sivaguru, M., Saw, J. J., Williams, J. C., Lieske, J. C., Krambeck, A. E., Romero, M. F., Chia, N. D., Schwaderer, A. L., Alcalde, R. E., Bruce, W. J., Wildman, D. E., Fried, G. A., Werth, C. J., Reeder, R. J., Yau, P. M., Sanford, R. A. & Fouke, B. W., Dec 1 2018, In : Scientific Reports. 8, 1, 13731.

Research output: Contribution to journalArticle

Calcium Oxalate
Kidney Calculi
Minerals
Geology
Kidney
5 Citations (Scopus)

NBCe1-a regulates proximal tubule ammonia metabolism under basal conditions and in response to metabolic acidosis

Lee, H. W., Osis, G., Harris, A. N., Fang, L., Romero, M. F., Handlogten, M. E., Verlander, J. W. & Weiner, I. D., Apr 1 2018, In : Journal of the American Society of Nephrology. 29, 4, p. 1182-1197 16 p.

Research output: Contribution to journalArticle

Basal Metabolism
Acidosis
Ammonia
Acids
Kidney
3 Citations (Scopus)

Prostatic collagen architecture in neutered and intact canines

Ruetten, H., Wegner, K. A., Romero, M. F., Wood, M. W., Marker, P. C., Strand, D., Colopy, S. A. & Vezina, C. M., Aug 1 2018, In : Prostate. 78, 11, p. 839-848 10 p.

Research output: Contribution to journalArticle

Canidae
Collagen
Prostate
Dogs
Castration
5 Citations (Scopus)

Reassessment of the Transport Mechanism of the Human Zinc Transporter SLC39A2

Franz, M. C., Pujol-Giménez, J., Montalbetti, N., Fernandez-Tenorio, M., DeGrado, T. R., Niggli, E., Romero, M. F. & Hediger, M. A., Jul 3 2018, In : Biochemistry. 57, 26, p. 3976-3986 11 p.

Research output: Contribution to journalArticle

Depolarization
Metal ions
Zinc
Screening
Experiments
5 Citations (Scopus)
Annexin A1
Annexins
Calcium Oxalate
Crystallization
Cell Adhesion
2017
1 Citation (Scopus)
Malpighian Tubules
Drosophila melanogaster
Epithelium
Ions
Tissue
2016
10 Citations (Scopus)

Effect of NBCe1 deletion on renal citrate and 2-oxoglutarate handling

Osis, G., Handlogten, M. E., Lee, H. W., Hering-Smith, K. S., Huang, W., Romero, M. F., Verlander, J. W. & Weiner, I. D., Apr 1 2016, In : Physiological Reports. 4, 8, e12778.

Research output: Contribution to journalArticle

Citric Acid
Acidosis
Kidney
Acids
glutamine-pyruvate aminotransferase
2 Citations (Scopus)

Functional and transport analyses of CLCN5 genetic changes identified in Dent disease patients

Tang, X., Brown, M. R., Cogal, A. G., Gauvin, D., Harris, P. C., Lieske, J. C., Romero, M. F. & Chang, M. H., Apr 1 2016, In : Physiological Reports. 4, 8, e12776.

Research output: Contribution to journalArticle

Dent Disease
Mutation
Endoplasmic Reticulum
Anions
HEK293 Cells
3 Citations (Scopus)

Insulin and SGK1 reduce the function of Na+/monocarboxylate transporter 1 (SMCT1/SLC5A8)

López-Barradas, A., González-Cid, T., Vázquez, N., Gavi-Maza, M., Reyes-Camacho, A., Velázquez-Villegas, L. A., Ramírez, V., Zandi-Nejad, K., Mount, D. B., Torres, N., Tovar, A. R., Romero, M. F., Gamba, G. & Plata, C., 2016, In : American Journal of Physiology - Cell Physiology. 311, 5, p. C720-C734

Research output: Contribution to journalArticle

Insulin
Pancreas
Messenger RNA
Oocytes
Complementary RNA
8 Citations (Scopus)

Na+/H+ exchange via the Drosophila vesicular glutamate transporter mediates activity-induced acid efflux from presynaptic terminals

Rossano, A. J., Kato, A., Minard, K. I., Romero, M. F. & Macleod, G. T., 2016, (Accepted/In press) In : Journal of Physiology.

Research output: Contribution to journalArticle

Vesicular Glutamate Transport Proteins
Presynaptic Terminals
Drosophila
Acids
Exocytosis
4 Citations (Scopus)

Sulfate transporters involved in sulfate secretion in the kidney are localized in the renal proximal tubule II of the elephant fish (Callorhinchus milii)

Hasegawa, K., Kato, A., Watanabe, T., Takagi, W., Romero, M. F., Bell, J. D., Toop, T., Donald, J. A. & Hyodo, S., Jul 1 2016, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 311, 1, p. R66-R78

Research output: Contribution to journalArticle

Proximal Kidney Tubule
Sulfates
Fishes
Kidney
Nephrons
2015
20 Citations (Scopus)

NBCe1 expression is required for normal renal ammonia metabolism

Handlogten, M. E., Osis, G., Lee, H. W., Romero, M. F., Verlander, J. W. & Weiner, I. D., Sep 1 2015, In : American Journal of Physiology - Renal Physiology. 309, 7, p. F658-F666

Research output: Contribution to journalArticle

Ammonia
Kidney
Gene Deletion
Bicarbonates
Glutaminase
9 Citations (Scopus)

Sulfate and thiosulfate inhibit oxalate transport via a dPrestin (Slc26a6)-dependent mechanism in an insect model of calcium oxalate nephrolithiasis

Landry, G. M., Hirata, T., Anderson, J. B., Cabrero, P., Gallo, C. J. R., Dow, J. A. T. & Romero, M. F., Nov 4 2015, In : American Journal of Physiology - Renal Physiology. 310, 2, p. F152-F159

Research output: Contribution to journalArticle

Thiosulfates
Oxalates
Calcium Oxalate
Sulfates
Insects
17 Citations (Scopus)

Transport proteins NHA1 and NHA2 are essential for survival, but have distinct transport modalities

Chintapalli, V. R., Kato, A., Henderson, L., Hirata, T., Woods, D. J., Overend, G., Davies, S. A., Romero, M. F. & Dow, J. A. T., Sep 15 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 37, p. 11720-11725 6 p.

Research output: Contribution to journalArticle

Sodium-Hydrogen Antiporter
Carrier Proteins
Gene Knockdown Techniques
Survival
Xenopus
2014
36 Citations (Scopus)

Chloride channels in stellate cells are essential for uniquely high secretion rates in neuropeptidestimulated Drosophila diuresis

Cabrero, P., Terhzaz, S., Romero, M. F., Davies, S. A., Blumenthal, E. M. & Dow, J. A. T., Sep 30 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 39, p. 14301-14306 6 p.

Research output: Contribution to journalArticle

Chloride Channels
Diuresis
Drosophila
Kinins
Malpighian Tubules
4 Citations (Scopus)

Identification and lateral membrane localization of cyclin M3, likely to be involved in renal Mg2+ handling in seawater fish

Islam, Z., Hayashi, N., Inoue, H., Umezawa, T., Kimura, Y., Doi, H., Romero, M. F., Hirose, S. & Kato, A., Sep 1 2014, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 307, 5

Research output: Contribution to journalArticle

Cyclins
Seawater
Takifugu
Fishes
Kidney
57 Citations (Scopus)

Investigation of the KIR4.1 potassium channel as a putative antigen in patients with multiple sclerosis: A comparative study

Brickshawana, A., Hinson, S. R., Romero, M. F., Lucchinetti, C. F., Guo, Y., Buttmann, M., McKeon, A. B., Pittock, S. J., Chang, M. H., Chen, A. P., Kryzer, T. J., Fryer, J. P., Jenkins, S. M., Cabre, P. & Lennon, V. A., 2014, In : The Lancet Neurology. 13, 8, p. 795-806 12 p.

Research output: Contribution to journalArticle

Potassium Channels
Multiple Sclerosis
Antigens
Immunoglobulin G
Serum
14 Citations (Scopus)
Sodium-Hydrogen Antiporter
Zebrafish
Xenopus
Oocytes
Butyrates
5 Citations (Scopus)

NBCe1A dimer assemble visualized by bimolecular fluorescence complementation

Chang, M. H., Chen, A. P. & Romero, M. F., Mar 15 2014, In : American Journal of Physiology - Renal Physiology. 306, 6

Research output: Contribution to journalArticle

Dimerization
Fluorescence
Proteins
Renal Tubular Acidosis
Mutation
48 Citations (Scopus)

The thellungiella salsuginea tonoplast aquaporin TsTIP1;2 functions in protection against multiple abiotic stresses

Wang, L. L., Chen, A. P., Zhong, N. Q., Liu, N., Wu, X. M., Wang, F., Yang, C. L., Romero, M. F. & Xia, G. X., Jan 2014, In : Plant and Cell Physiology. 55, 1, p. 148-161 14 p.

Research output: Contribution to journalArticle

Aquaporin 2
Aquaporins
aquaporins
tonoplast
abiotic stress
2013
26 Citations (Scopus)

Drosophila melanogaster as an emerging translational model of human nephrolithiasis

Miller, J., Chi, T., Kapahi, P., Kahn, A. J., Kim, M. S., Hirata, T., Romero, M. F., Dow, J. A. T. & Stoller, M. L., Nov 2013, In : Journal of Urology. 190, 5, p. 1648-1656 9 p.

Research output: Contribution to journalArticle

Nephrolithiasis
Drosophila melanogaster
Drosophila
Malpighian Tubules
Calcium Oxalate
11 Citations (Scopus)

Expression of a novel isoform of Na+/H+ exchanger 3 in the kidney and intestine of banded houndshark, Triakis scyllium

Li, S., Kato, A., Takabe, S., Chen, A. P., Romero, M. F., Umezawa, T., Nakada, T., Hyodo, S. & Hirose, S., 2013, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 304, 10

Research output: Contribution to journalArticle

Sodium-Hydrogen Antiporter
Intestines
Protein Isoforms
Elasmobranchii
Kidney
8 Citations (Scopus)

Identification and properties of a novel variant of NBC4 (Na +/HCO3 - co-transporter 4) that is predominantly expressed in the choroid plexus

Fukuda, H., Hirata, T., Nakamura, N., Kato, A., Kawahara, K., Wakabayashi, S., Chang, M. H., Romero, M. F. & Hirose, S., Feb 15 2013, In : Biochemical Journal. 450, 1, p. 179-187 9 p.

Research output: Contribution to journalArticle

Symporters
Choroid Plexus
Cerebrospinal fluid
Membranes
Sodium-Bicarbonate Symporters
9 Citations (Scopus)

Identification and proximal tubular localization of the Mg2+ transporter, Slc41a1, in a seawater fish

Islam, Z., Hayashi, N., Yamamoto, Y., Doi, H., Romero, M. F., Hirose, S. & Kato, A., May 8 2013, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 305, 4

Research output: Contribution to journalArticle

Takifugu
Seawater
Fishes
Tetraodontiformes
Kidney
148 Citations (Scopus)

The SLC4 family of bicarbonate (HCO3 -) transporters

Romero, M. F., Chen, A. P., Parker, M. D. & Boron, W. F., Apr 2013, In : Molecular Aspects of Medicine. 34, 2-3, p. 159-182 24 p.

Research output: Contribution to journalArticle

Bicarbonates
Erythrocyte Anion Exchange Protein 1
Protein Transport
Cell Size
Membrane Proteins
2012
18 Citations (Scopus)

Euryhaline pufferfish NBCe1 differs from nonmarine species NBCe1 physiology

Chang, M. H., Plata, C., Kurita, Y., Kato, A., Hirose, S. & Romero, M. F., Apr 15 2012, In : American Journal of Physiology - Cell Physiology. 302, 8

Research output: Contribution to journalArticle

Takifugu
Tetraodontiformes
Seawater
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
Salts
14 Citations (Scopus)

Functional analysis of nonsynonymous single nucleotide polymorphisms in human SLC26A9

Chen, A. P., Chang, M. H. & Romero, M. F., Aug 2012, In : Human Mutation. 33, 8, p. 1275-1284 10 p.

Research output: Contribution to journalArticle

Single Nucleotide Polymorphism
Mutation
Anions
Electrodes
Chloride-Bicarbonate Antiporters
25 Citations (Scopus)

In vivo Drosophilia genetic model for calcium oxalate nephrolithiasis

Hirata, T., Cabrero, P., Berkholz, D. S., Bondeson, D. P., Ritman, E. L., Thompson, J. R., Dow, J. A. T. & Romero, M. F., Dec 1 2012, In : American Journal of Physiology - Renal Physiology. 303, 11

Research output: Contribution to journalArticle

Nephrolithiasis
Calcium Oxalate
Oxalates
Genetic Models
Diptera
20 Citations (Scopus)

Ion and solute transport by Prestin in Drosophila and Anopheles

Hirata, T., Czapar, A., Brin, L., Haritonova, A., Bondeson, D. P., Linser, P., Cabrero, P., Thompson, J., Dow, J. A. T. & Romero, M. F., Apr 2012, In : Journal of Insect Physiology. 58, 4, p. 563-569 7 p.

Research output: Contribution to journalArticle

Anopheles
Ion Transport
ion transport
Drosophila
Anions
165 Citations (Scopus)

Molecular outcomes of neuromyelitis optica (NMO)-IgG binding to aquaporin-4 in astrocytes

Hinson, S. R., Romero, M. F., Popescu, B. F. G., Lucchinetti, C. F., Fryer, J. P., Wolburg, H., Fallier-Becker, P., Noell, S. & Lennon, V. A., Jan 24 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 4, p. 1245-1250 6 p.

Research output: Contribution to journalArticle

Aquaporin 4
Neuromyelitis Optica
Astrocytes
Immunoglobulin G
Protein Isoforms
9 Citations (Scopus)

O 2-filled swimbladder employs monocarboxylate transporters for the generation of O 2 by lactate-induced root effect hemoglobin

Umezawa, T., Kato, A., Ogoshi, M., Ookata, K., Munakata, K., Yamamoto, Y., Islam, Z., Doi, H., Romero, M. F. & Hirose, S., Apr 4 2012, In : PLoS One. 7, 4, e34579.

Research output: Contribution to journalArticle

Air Sacs
swim bladder
lactic acid
lactates
transporters
15 Citations (Scopus)

Slc4-like anion transporters of the larval mosquito alimentary canal

Linser, P. J., Neira Oviedo, M., Hirata, T., Seron, T. J., Smith, K. E., Piermarini, P. M. & Romero, M. F., Apr 2012, In : Journal of Insect Physiology. 58, 4, p. 551-562 12 p.

Research output: Contribution to journalArticle

Carbonates
Bicarbonates
Culicidae
bicarbonates
digestive tract
22 Citations (Scopus)

Substrate- and pH-specific antifolate transport mediated by organic anion-transporting polypeptide 2B1 (OATP2B1-SLCO2B1)

Visentin, M., Chang, M. H., Romero, M. F., Zhao, R. & Goldman, I. D., Feb 2012, In : Molecular Pharmacology. 81, 2, p. 134-142 9 p.

Research output: Contribution to journalArticle

Folic Acid Antagonists
Pemetrexed
Anions
Peptides
Folic Acid
2011
18 Citations (Scopus)

ATP-sensitive potassium (K ATP) channel activation decreases intraocular pressure in the anterior chamber of the eye

Roy Chowdhury, U., Bahler, C. K., Hann, C. R., Chang, M., Resch, Z. T., Romero, M. F. & Fautsch, M. P., Aug 2011, In : Investigative Ophthalmology and Visual Science. 52, 9, p. 6435-6442 8 p.

Research output: Contribution to journalArticle

KATP Channels
Anterior Chamber
Intraocular Pressure
Adenosine Triphosphate
Trabecular Meshwork
5 Citations (Scopus)
Sodium-Calcium Exchanger
Seawater
Takifugu
Fishes
Kidney
2 Citations (Scopus)

Primers on molecular pathways: Bicarbonate transport by the pancreas

Sindić, A., Sussman, C. R. & Romero, M. F., Mar 2011, In : Pancreatology. 10, 6, p. 660-663 4 p.

Research output: Contribution to journalArticle

Inositol 1,4,5-Trisphosphate Receptors
Exocrine Pancreas
Cystic Fibrosis Transmembrane Conductance Regulator
Chloride Channels
Bicarbonates
76 Citations (Scopus)

Regulation of electroneutral NaCl absorption by the small intestine

Kato, A. & Romero, M. F., 2011, In : Annual Review of Physiology. 73, p. 261-281 21 p.

Research output: Contribution to journalArticle

Small Intestine
Macromolecular Substances
Autonomic Pathways
Endocrine System
Intestinal Mucosa
50 Citations (Scopus)

Synthesis, biological, and antitumor activity of a highly potent 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitor with proton-coupled folate transporter and folate receptor selectivity over the reduced folate carrier that inhibits β-glycinamide ribonucleotide formyltransferase

Wang, L., Desmoulin, S. K., Cherian, C., Polin, L., White, K., Kushner, J., Fulterer, A., Chang, M. H., Mitchell-Ryan, S., Stout, M., Romero, M. F., Hou, Z., Matherly, L. H. & Gangjee, A., Oct 27 2011, In : Journal of Medicinal Chemistry. 54, 20, p. 7150-7164 15 p.

Research output: Contribution to journalArticle

Proton-Coupled Folate Transporter
Hydroxymethyl and Formyl Transferases
Reduced Folate Carrier Protein
Folic Acid Antagonists
Folic Acid
23 Citations (Scopus)

Two types of chloride transporters are required for GABA A receptor-mediated inhibition in C. elegans

Bellemer, A., Hirata, T., Romero, M. F. & Koelle, M. R., May 4 2011, In : EMBO Journal. 30, 9, p. 1852-1863 12 p.

Research output: Contribution to journalArticle

GABA-A Receptors
Chlorides
gamma-Aminobutyric Acid
Brain
Animals
2010
63 Citations (Scopus)
Drosophila
Kidney
Malpighian Tubules
Bartter Syndrome
Inwardly Rectifying Potassium Channel
31 Citations (Scopus)

Properties of the Arg376 residue of the proton-coupled folate transporter (PCFT-SLC46A1) and a glutamine mutant causing hereditary folate malabsorption

Mahadeo, K., Diop-Bove, N., Shin, D., Unal, E. S., Teo, J., Zhao, R., Chang, M. H., Fulterer, A., Romero, M. F. & Goldman, I. D., Nov 2010, In : American Journal of Physiology - Cell Physiology. 299, 5

Research output: Contribution to journalArticle

Proton-Coupled Folate Transporter
Pemetrexed
Leucovorin
Glutamine
Folic Acid

SNPs of metabolism, not stones

Romero, M. F., Oct 2010, In : American Journal of Physiology - Renal Physiology. 299, 4

Research output: Contribution to journalArticle

Sodium-Dependent Organic Anion Transporters
Dicarboxylic Acid Transporters
Symporters
Animal Disease Models
Nephrolithiasis
39 Citations (Scopus)

Targeting the proton-coupled folate transporter for selective delivery of 6-substituted pyrrolo[2,3-d]pyrimidine antifolate inhibitors of de novo purine biosynthesis in the chemotherapy of solid tumors

Desmoulin, S. K., Wang, Y., Wu, J., Stout, M., Hou, Z., Fulterer, A., Chang, M. H., Romero, M. F., Cherian, C., Gangjee, A. & Matherly, L. H., 2010, In : Molecular Pharmacology. 78, 4, p. 577-587 11 p.

Research output: Contribution to journalArticle

Proton-Coupled Folate Transporter
Folic Acid Antagonists
Hydroxymethyl and Formyl Transferases
Reduced Folate Carrier Protein
Drug Therapy
2009
18 Citations (Scopus)

Cloning, localization, and functional expression of the electrogenic Na+ bicarbonate cotransporter (NBCe1) from zebrafish

Sussman, C. R., Zhao, J., Plata, C., Lu, J., Daly, C., Angle, N., DiPiero, J., Drummond, I. A., Liang, J. O., Boron, W. F., Romero, M. F. & Chang, M. H., 2009, In : American Journal of Physiology - Cell Physiology. 297, 4

Research output: Contribution to journalArticle

Zebrafish
Bicarbonates
Organism Cloning
Water-Electrolyte Balance
Xenopus
27 Citations (Scopus)

Identification of renal transporters involved in sulfate excretion in marine teleost fish

Kato, A., Chang, M. H., Kurita, Y., Nakada, T., Ogoshi, M., Nakazato, T., Doi, H., Hirose, S. & Romero, M. F., Dec 2009, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 297, 6

Research output: Contribution to journalArticle

Seawater
Sulfates
Fishes
Takifugu
Kidney