Melissa E Murray, PhD

  • 7055 Citations
  • 46 Scopus h-Index
20022019
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Research Output 2002 2019

2019

Antemortem volume loss mirrors TDP-43 staging in older adults with non-frontotemporal lobar degeneration

Bejanin, A., Murray, M. E., Martin, P., Botha, H., Tosakulwong, N., Schwarz, C. G., Senjem, M. L., Chételat, G., Kantarci, K., Jack, C. R., Boeve, B. F., Knopman, D. S., Petersen, R. C., Giannini, C., Parisi, J. E., Dickson, D. W., Whitwell, J. L. & Josephs, K. A., Nov 1 2019, In : Brain : a journal of neurology. 142, 11, p. 3621-3635 15 p.

Research output: Contribution to journalArticle

Temporal Lobe
Pathology
Alzheimer Disease
Frontotemporal Lobar Degeneration
Lewy Bodies
3 Citations (Scopus)

APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1

Tachibana, M., Holm, M. L., Liu, C-C., Shinohara, M., Aikawa, T., Oue, H., Yamazaki, Y., Martens, Y. A., Murray, M. E., Sullivan, P. M., Weyer, K., Glerup, S., Dickson, D. W., Bu, G. D. & Kanekiyo, T., Mar 1 2019, In : Journal of Clinical Investigation. 129, 3, p. 1272-1277 6 p.

Research output: Contribution to journalArticle

LDL Receptors
Amyloid
Apolipoprotein E4
Pathology
Alzheimer Disease
1 Citation (Scopus)

Association of MAPT H1 subhaplotypes with neuropathology of lewy body disease

Heckman, M. G., Kasanuki, K., Brennan, R. R., Labbé, C., Vargas, E. R., Soto, A. I., Murray, M. E., Koga, S., Dickson, D. W. & Ross, O. A., Jan 1 2019, In : Movement Disorders.

Research output: Contribution to journalArticle

Lewy Body Disease
Microtubule-Associated Proteins
Haplotypes
Tyrosine 3-Monooxygenase
Lewy Bodies
5 Citations (Scopus)

Association of MAPT Subhaplotypes with Risk of Progressive Supranuclear Palsy and Severity of Tau Pathology

Heckman, M. G., Brennan, R. R., Labbé, C., Soto, A. I., Koga, S., Deture, M., Murray, M. E., Petersen, R. C., Boeve, B. F., Van Gerpen, J. A., Uitti, R. J., Wszolek, Z. K., Rademakers, R. V., Dickson, D. W. & Ross, O. A., Jan 1 2019, In : JAMA neurology.

Research output: Contribution to journalArticle

Progressive Supranuclear Palsy
Microtubule-Associated Proteins
Pathology
Haplotypes
Odds Ratio
1 Citation (Scopus)
Tauopathies
DNA-Binding Proteins
Atrophy
Brain
Amygdala
1 Citation (Scopus)

Clinicopathologic subtype of Alzheimer's disease presenting as corticobasal syndrome

Sakae, N., Josephs, K. A., Litvan, I., Murray, M. E., Duara, R., Uitti, R. J., Wszolek, Z. K., van Gerpen, J., Graff Radford, N. R. & Dickson, D. W., Sep 1 2019, In : Alzheimer's and Dementia. 15, 9, p. 1218-1228 11 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Substantia Nigra
Pathology
Extremities
Apraxias

Corrigendum: Increased cytoplasmic TDP-43 reduces global protein synthesis by interacting with RACK1 on polyribosomes

Russo, A., Scardigli, R., La Regina, F., Murray, M. E., Romano, N., Dickson, D. W., Wolozin, B., Cattaneo, A. & Ceci, M., Apr 1 2019, In : Human molecular genetics. 28, 7, 1 p.

Research output: Contribution to journalArticle

Open Access
Polyribosomes
Proteins
corrigendum

Cross-sectional associations of tau-PET signal with cognition in cognitively unimpaired adults

Lowe, V. J., Bruinsma, T. J., Wiste, H. J., Min, H. K., Weigand, S. D., Fang, P., Senjem, M. L., Therneau, T. M., Boeve, B. F., Josephs, K. A., Pandey, M. K., Murray, M. E., Kantarci, K., Jones, D. T., Vemuri, P., Graff-Radford, J., Schwarz, C. G., Machulda, M. M., Mielke, M. M., Roberts, R. O. & 3 others, Knopman, D. S., Petersen, R. C. & Jack, C. R., Jul 2 2019, In : Neurology. 93, 1, p. e29-e39

Research output: Contribution to journalArticle

Entorhinal Cortex
Temporal Lobe
Cognition
Amyloid
Brain
5 Citations (Scopus)

Distinct cytokine profiles in human brains resilient to Alzheimer's pathology

Barroeta-Espar, I., Weinstock, L. D., Perez-Nievas, B. G., Meltzer, A. C., Siao Tick Chong, M., Amaral, A. C., Murray, M. E., Moulder, K. L., Morris, J. C., Cairns, N. J., Parisi, J. E., Lowe, V., Petersen, R. C., Kofler, J., Ikonomovic, M. D., López, O., Klunk, W. E., Mayeux, R. P., Frosch, M. P., Wood, L. B. & 1 others, Gomez-Isla, T., Jan 1 2019, In : Neurobiology of Disease. 121, p. 327-337 11 p.

Research output: Contribution to journalArticle

Pathology
Cytokines
Brain
Dementia
Interleukin-6
3 Citations (Scopus)

Ethnoracial differences in Alzheimer's disease from the FLorida Autopsied Multi-Ethnic (FLAME)cohort

Santos, O. A., Pedraza, O. D., Lucas, J. A., Duara, R., Greig-Custo, M. T., Hanna Al-Shaikh, F. S., Liesinger, A. M., Bieniek, K. F., Hinkle, K. M., Lesser, E. R., Crook, J., Carrasquillo, M. M., Ross, O. A., Taner, N., Graff Radford, N. R., Dickson, D. W. & Murray, M. E., May 1 2019, In : Alzheimer's and Dementia. 15, 5, p. 635-643 9 p.

Research output: Contribution to journalArticle

Open Access
Hispanic Americans
Alzheimer Disease
Sclerosis
Age of Onset
Lewy Body Disease

Evaluation of Associations of Alzheimer's Disease Risk Variants that Are Highly Expressed in Microglia with Neuropathological Outcome Measures

Sakae, N., Heckman, M. G., Vargas, E. R., Carrasquillo, M. M., Murray, M. E., Kasanuki, K., Ertekin-Taner, N., Younkin, S. G. & Dickson, D. W., Jan 1 2019, In : Journal of Alzheimer's Disease. 70, 3, p. 659-666 8 p.

Research output: Contribution to journalArticle

Microglia
Alzheimer Disease
Outcome Assessment (Health Care)
Cerebral Amyloid Angiopathy
Disease Susceptibility

Extensive transcriptomic study emphasizes importance of vesicular transport in C9orf72 expansion carriers

Dickson, D. W., Baker, M. C., Jackson, J. L., Dejesus-Hernandez, M., Finch, N. C. A., Tian, S., Heckman, M. G., Pottier, C., Gendron, T. F., Murray, M. E., Ren, Y., Reddy, J. S., Graff-Radford, N. R., Boeve, B. F., Petersen, R. C., Knopman, D. S., Josephs, K. A., Petrucelli, L., Oskarsson, B., Sheppard, J. W. & 3 others, Asmann, Y. W., Rademakers, R. & Van Blitterswijk, M., Oct 8 2019, In : Acta Neuropathologica Communications. 7, 1, 150.

Research output: Contribution to journalArticle

Open Access
Frontotemporal Lobar Degeneration
Motor Neuron Disease
Monomeric GTP-Binding Proteins
Dipeptides
GTP Phosphohydrolase Activators
6 Citations (Scopus)

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD

Pottier, C., Ren, Y., Perkerson, R. B., Baker, M., Jenkins, G. D., van Blitterswijk, M., DeJesus-Hernandez, M., van Rooij, J. G. J., Murray, M. E., Christopher, E., McDonnell, S. K., Fogarty, Z., Batzler, A., Tian, S., Vicente, C. T., Matchett, B., Karydas, A. M., Hsiung, G. Y. R., Seelaar, H., Mol, M. O. & 85 others, Finger, E. C., Graff, C., Öijerstedt, L., Neumann, M., Heutink, P., Synofzik, M., Wilke, C., Prudlo, J., Rizzu, P., Simon-Sanchez, J., Edbauer, D., Roeber, S., Diehl-Schmid, J., Evers, B. M., King, A., Mesulam, M. M., Weintraub, S., Geula, C., Bieniek, K. F., Petrucelli, L., Ahern, G. L., Reiman, E. M., Woodruff, B. K., Caselli, R. J., Huey, E. D., Farlow, M. R., Grafman, J., Mead, S., Grinberg, L. T., Spina, S., Grossman, M., Irwin, D. J., Lee, E. B., Suh, E. R., Snowden, J., Mann, D., Ertekin-Taner, N., Uitti, R. J., Wszolek, Z. K., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Hodges, J. R., Piguet, O., Geier, E. G., Yokoyama, J. S., Rissman, R. A., Rogaeva, E., Keith, J., Zinman, L., Tartaglia, M. C., Cairns, N. J., Cruchaga, C., Ghetti, B., Kofler, J., Lopez, O. L., Beach, T. G., Arzberger, T., Herms, J., Honig, L. S., Vonsattel, J. P., Halliday, G. M., Kwok, J. B., White, C. L., Gearing, M., Glass, J., Rollinson, S., Pickering-Brown, S., Rohrer, J. D., Trojanowski, J. Q., Van Deerlin, V., Bigio, E. H., Troakes, C., Al-Sarraj, S., Asmann, Y., Miller, B. L., Graff-Radford, N. R., Boeve, B. F., Seeley, W. W., Mackenzie, I. R. A., van Swieten, J. C., Dickson, D. W., Biernacka, J. M. & Rademakers, R., Jan 1 2019, In : Acta neuropathologica.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Frontotemporal Dementia
Genome
Genes
Mutation
25 Citations (Scopus)

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report

Nelson, P. T., Dickson, D. W., Trojanowski, J. Q., Jack, C. R. J., Boyle, P. A., Arfanakis, K., Rademakers, R. V., Alafuzoff, I., Attems, J., Brayne, C., Coyle-Gilchrist, I. T. S., Chui, H. C., Fardo, D. W., Flanagan, M. E., Halliday, G., Hokkanen, S. R. K., Hunter, S., Jicha, G. A., Katsumata, Y., Kawas, C. H. & 15 others, Keene, C. D., Kovacs, G. G., Kukull, W. A., Levey, A. I., Makkinejad, N., Montine, T. J., Murayama, S., Murray, M. E., Nag, S., Rissman, R. A., Seeley, W. W., Sperling, R. A., White, C. L., Yu, L. & Schneider, J. A., Jun 1 2019, In : Brain : a journal of neurology. 142, 6, p. 1503-1527 25 p.

Research output: Contribution to journalArticle

Open Access
Brain Diseases
Consensus
TDP-43 Proteinopathies
Frontotemporal Lobar Degeneration
Brain

Microglia in frontotemporal lobar degeneration with progranulin or C9ORF72 mutations

Sakae, N., Roemer, S. F., Bieniek, K. F., Murray, M. E., Baker, M. C., Kasanuki, K., Graff Radford, N. R., Petrucelli, L., Van Blitterswijk, M., Rademakers, R. V. & Dickson, D. W., Jan 1 2019, (Accepted/In press) In : Annals of Clinical and Translational Neurology.

Research output: Contribution to journalArticle

Open Access
Frontotemporal Lobar Degeneration
Microglia
Mutation
Immunohistochemistry
Apraxias
8 Citations (Scopus)

Multisite study of the relationships between antemortem [11C]PIB-PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology

La Joie, R., Ayakta, N., Seeley, W. W., Borys, E., Boxer, A. L., DeCarli, C., Doré, V., Grinberg, L. T., Huang, E., Hwang, J. H., Ikonomovic, M. D., Jack, C. R. J., Jagust, W. J., Jin, L. W., Klunk, W. E., Kofler, J., Lesman-Segev, O. H., Lockhart, S. N., Lowe, V., Masters, C. L. & 15 others, Mathis, C. A., McLean, C. L., Miller, B. L., Mungas, D., O'Neil, J. P., Olichney, J. M., Parisi, J. E., Petersen, R. C., Rosen, H. J., Rowe, C. C., Spina, S., Vemuri, P. D., Villemagne, V. L., Murray, M. E. & Rabinovici, G. D., Feb 1 2019, In : Alzheimer's and Dementia. 15, 2, p. 205-216 12 p.

Research output: Contribution to journalArticle

Amyloid Plaques
Area Under Curve
Alzheimer Disease
Pathology
Sensitivity and Specificity
1 Citation (Scopus)

Neuroimaging correlates with neuropathologic schemes in neurodegenerative disease

Lowe, V., Lundt, E. S., Albertson, S. M., Przybelski, S. A., Senjem, M. L., Parisi, J. E., Kantarci, K. M., Boeve, B. F., Jones, D. T., Knopman, D. S., Jack, C. R. J., Dickson, D. W., Petersen, R. C. & Murray, M. E., Jan 1 2019, In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Neuroimaging
Neurodegenerative Diseases
Amyloid Plaques
Alzheimer Disease
Autopsy

Neuropathologic basis of frontotemporal dementia in progressive supranuclear palsy

Sakae, N., Josephs, K. A., Litvan, I., Murray, M. E., Duara, R., Uitti, R. J., Wszolek, Z. K., Graff Radford, N. R. & Dickson, D. W., Jan 1 2019, (Accepted/In press) In : Movement Disorders.

Research output: Contribution to journalArticle

Open Access
Progressive Supranuclear Palsy
Frontotemporal Dementia
Pathology
Neuroglia
5 Citations (Scopus)

Pathological, imaging and genetic characteristics support the existence of distinct TDP-43 types in non-FTLD brains

Josephs, K. A., Murray, M. E., Tosakulwong, N., Weigand, S. D., Serie, A. M., Perkerson, R. B., Matchett, B. J., Jack, C. R. J., Knopman, D. S., Petersen, R. C., Parisi, J. E., Petrucelli, L., Baker, M., Rademakers, R. V., Whitwell, J. L. & Dickson, D. W., Jan 1 2019, (Accepted/In press) In : Acta Neuropathologica.

Research output: Contribution to journalArticle

Amygdala
Frontotemporal Lobar Degeneration
Brain
Neuroimaging
Hippocampus
8 Citations (Scopus)

Perspectives on ethnic and racial disparities in Alzheimer's disease and related dementias: Update and areas of immediate need

International Society to Advance Alzheimer's Research and Treatment, Alzheimer's Association, Feb 1 2019, In : Alzheimer's and Dementia. 15, 2, p. 292-312 21 p.

Research output: Contribution to journalShort survey

Dementia
Alzheimer Disease
Research
Population

Reply: LATE to the PART-y

Nelson, P. T., Dickson, D. W., Trojanowski, J. Q., Jack, C. R., Boyle, P. A., Arfanakis, K., Rademakers, R., Alafuzoff, I., Attems, J., Brayne, C., Coyle-Gilchrist, I. T. S., Fardo, D. W., Flanagan, M. E., Halliday, G., Hunter, S., Jicha, G. A., Katsumata, Y., Kawas, C. H., Dirk Keene, C., Kovacs, G. G. & 10 others, Kukull, W. A., Levey, A. I., Makkinejad, N., Montine, T. J., Murray, M. E., Nag, S., Seeley, W. W., Sperling, R. A., White, C. L. & Schneider, J. A., Sep 1 2019, In : Brain. 142, 9, p. 1-3 3 p.

Research output: Contribution to journalLetter

4 Citations (Scopus)

Selective loss of cortical endothelial tight junction proteins during Alzheimer's disease progression

Yamazaki, Y., Shinohara, M., Shinohara, M., Yamazaki, A., Murray, M. E., Liesinger, A. M., Heckman, M. G., Lesser, E. R., Parisi, J. E., Petersen, R. C., Dickson, D. W., Kanekiyo, T. & Bu, G. D., Apr 1 2019, In : Brain : a journal of neurology. 142, 4, p. 1077-1092 16 p.

Research output: Contribution to journalArticle

Tight Junction Proteins
Disease Progression
Alzheimer Disease
Amyloid
Brain

Selective Vulnerability of the Nucleus Basalis of Meynert among Neuropathologic Subtypes of Alzheimer Disease

Hanna Al-Shaikh, F. S., Duara, R., Crook, J. E., Lesser, E. R., Schaeverbeke, J., Hinkle, K. M., Ross, O. A., Ertekin-Taner, N., Pedraza, O., Dickson, D. W., Graff-Radford, N. R. & Murray, M. E., Jan 1 2019, (Accepted/In press) In : JAMA neurology.

Research output: Contribution to journalArticle

Open Access
Basal Nucleus of Meynert
Alzheimer Disease
Neurofibrillary Tangles
Cholinergic Agents
Demography

Tau Subtypes of Alzheimer's Disease Determined in vivo Using Flortaucipir PET Imaging

Charil, A., Shcherbinin, S., Southekal, S., Devous, M. D., Mintun, M., Murray, M. E., Miller, B. B. & Schwarz, A. J., Jan 1 2019, In : Journal of Alzheimer's Disease. 71, 3, p. 1037-1048 12 p.

Research output: Contribution to journalArticle

Positron-Emission Tomography
Alzheimer Disease
Hippocampus
Neurofibrillary Tangles
Autopsy
5 Citations (Scopus)
alpha-Synuclein
Amyloid
Blood Vessels
Pathology
Apolipoprotein E4
2018
5 Citations (Scopus)

Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease

Hou, X., Fiesel, F., Truban, D., Castanedes Casey, M., Lin, W. L., Soto, A. I., Tacik, P., Rousseau, L. G., Diehl, N. N., Heckman, M. G., Lorenzo-Betancor, O., Ferrer, I., Arbelo, J. M., Steele, J. C., Farrer, M. J., Cornejo-Olivas, M., Torres, L., Mata, I. F., Graff Radford, N. R., Wszolek, Z. K. & 4 others, Ross, O. A., Murray, M. E., Dickson, D. W. & Springer, W., Jan 1 2018, (Accepted/In press) In : Autophagy.

Research output: Contribution to journalArticle

Mitochondrial Degradation
Lewy Body Disease
Ubiquitin
Parkinson Disease
Carbonyl Cyanide m-Chlorophenyl Hydrazone
12 Citations (Scopus)

APOE ε2 is associated with increased tau pathology in primary tauopathy

Zhao, N., Liu, C-C., Van Ingelgom, A. J., Linares, C., Kurti, A., Knight, J. A., Heckman, M. G., Diehl, N. N., Shinohara, M., Martens, Y. A., Attrebi, O. N., Petrucelli, L., Fryer, J. D., Wszolek, Z. K., Graff Radford, N. R., Caselli, R. J., Sanchez-Contreras, M. Y., Rademakers, R. V., Murray, M. E., Koga, S. & 3 others, Dickson, D. W., Ross, O. A. & Bu, G. D., Dec 1 2018, In : Nature Communications. 9, 1, 4388.

Research output: Contribution to journalArticle

Apolipoprotein E2
Tauopathies
pathology
Pathology
mice
17 Citations (Scopus)

APOE ε4 is associated with severity of Lewy body pathology independent of Alzheimer pathology

Dickson, D. W., Heckman, M. G., Murray, M. E., Soto, A. I., Walton, R. L., Diehl, N. N., Van Gerpen, J. A., Uitti, R. J., Wszolek, Z. K., Taner, N., Knopman, D. S., Petersen, R. C., Graff Radford, N. R., Boeve, B. F., Bu, G. D., Ferman, T. J. & Ross, O. A., Sep 18 2018, In : Neurology. 91, 12, p. e1182-e1195

Research output: Contribution to journalArticle

Lewy Bodies
Pathology
Alzheimer Disease
Dementia
Odds Ratio
9 Citations (Scopus)

Association between microinfarcts and blood pressure trajectories

Graff-Radford, J., Raman, M. R., Rabinstein, A., Przybelski, S. A., Lesnick, T. G., Boeve, B. F., Murray, M. E., Dickson, D. W., Ross Reichard, R., Parisi, J. E., Knopman, D. S., Petersen, R. C., Jack, C. R. J. & Kantarci, K. M., Feb 1 2018, In : JAMA Neurology. 75, 2, p. 212-218 7 p.

Research output: Contribution to journalArticle

Blood Pressure
Autopsy
Cohort Studies
Logistic Models
Regression Analysis
8 Citations (Scopus)

Association of Apolipoprotein e ϵ4 with Transactive Response DNA-Binding Protein 43

Wennberg, A. M., Tosakulwong, N., Lesnick, T. G., Murray, M. E., Whitwell, J. L., Liesinger, A. M., Petrucelli, L., Boeve, B. F., Parisi, J. E., Knopman, D. S., Petersen, R. C., Dickson, D. W. & Josephs, K. A., Jan 1 2018, (Accepted/In press) In : JAMA Neurology. p. E1-E8

Research output: Contribution to journalArticle

Apolipoproteins
DNA-Binding Proteins
Apolipoprotein E4
Alzheimer Disease
Apolipoproteins E
2 Citations (Scopus)
Lewy Body Disease
Single-Photon Emission-Computed Tomography
Dementia
Corpus Striatum
Putamen
7 Citations (Scopus)

Daytime sleepiness in dementia with Lewy bodies is associated with neuronal depletion of the nucleus basalis of Meynert

Kasanuki, K., Ferman, T. J., Murray, M. E., Heckman, M. G., Pedraza, O. D., Hanna Al-Shaikh, F. S., Mishima, T., Diehl, N. N., Van Gerpen, J. A., Uitti, R. J., Wszolek, Z. K., Graff Radford, N. R. & Dickson, D. W., Jan 1 2018, (Accepted/In press) In : Parkinsonism and Related Disorders.

Research output: Contribution to journalArticle

Basal Nucleus of Meynert
Lewy Body Disease
Dementia
Hallucinations
Cholinergic Agents
10 Citations (Scopus)

Diffuse Lewy body disease manifesting as corticobasal syndrome: A rare form of Lewy body disease

Kasanuki, K., Josephs, K. A., Ferman, T. J., Murray, M. E., Koga, S., Konno, T., Sakae, N., Parks, A., Uitti, R. J., Van Gerpen, J. A., Graff Radford, N. R., Wszolek, Z. K. & Dickson, D. W., Jul 17 2018, In : Neurology. 91, 3, p. e268-e279

Research output: Contribution to journalArticle

Lewy Body Disease
Synucleins
Progressive Supranuclear Palsy
Lewy Bodies
Motor Cortex
5 Citations (Scopus)

Divergent brain gene expression patterns associate with distinct cell-specific tau neuropathology traits in progressive supranuclear palsy

Allen, M., Wang, X., Serie, D. J., Strickland, S. L., Burgess, J. D., Koga, S., Younkin, C. S., Nguyen, T. T., Malphrus, K. G., Lincoln, S. J., Alamprese, M., Zhu, K., Chang, R., Carrasquillo, M. M., Kouri, N., Murray, M. E., Reddy, J. S., Funk, C., Price, N. D., Golde, T. E. & 5 others, Younkin, S. G., Asmann, Y., Crook, J., Dickson, D. W. & Taner, N., Jan 1 2018, (Accepted/In press) In : Acta Neuropathologica.

Research output: Contribution to journalArticle

Progressive Supranuclear Palsy
Gene Expression
Brain
Pathology
Coiled Bodies
3 Citations (Scopus)
Temporal Lobe
Alzheimer Disease
Brain
Neurofibrillary Tangles
Tomography
10 Citations (Scopus)

FDG-PET in tau-negative amnestic dementia resembles that of autopsy-proven hippocampal sclerosis

Botha, H., Mantyh, W. G., Murray, M. E., Knopman, D. S., Przybelski, S. A., Wiste, H. J., Graff-Radford, J., Josephs, K. A., Schwarz, C., Kremers, W. K., Boeve, B. F., Petersen, R. C., Machulda, M. M., Parisi, J. E., Dickson, D. W., Lowe, V., Jack, C. R. J. & Jones, D. T., Apr 1 2018, In : Brain. 141, 4, p. 1201-1217 17 p.

Research output: Contribution to journalArticle

Sclerosis
Dementia
Autopsy
Amyloid
Fluorodeoxyglucose F18
2 Citations (Scopus)

Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity

Nicholson, A. M., Zhou, X., Perkerson, R. B., Parsons, T. M., Chew, J., Brooks, M., DeJesus-Hernandez, M., Finch, N. C. A., Matchett, B. J., Kurti, A., Jansen-West, K. R., Perkerson, E., Daughrity, L., Castanedes-Casey, M., Rousseau, L., Phillips, V., Hu, F., Gendron, T. D., Murray, M. E., Dickson, D. W. & 3 others, Fryer, J. D., Petrucelli, L. & Rademakers, R. V., May 31 2018, In : Acta Neuropathologica Communications. 6, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Frontotemporal Lobar Degeneration
Frontotemporal Dementia
Phenotype
Mutation
Dipeptides
14 Citations (Scopus)
Open Access
Frontotemporal Lobar Degeneration
Dipeptides
Brain Diseases
Motor Neuron Disease
Polymers
13 Citations (Scopus)

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study

Pottier, C., Zhou, X., Perkerson, R. B., Baker, M., Jenkins, G. D., Serie, D. J., Ghidoni, R., Benussi, L., Binetti, G., López de Munain, A., Zulaica, M., Moreno, F., Le Ber, I., Pasquier, F., Hannequin, D., Sánchez-Valle, R., Antonell, A., Lladó, A., Parsons, T. M., Finch, N. C. A. & 113 others, Finger, E. C., Lippa, C. F., Huey, E. D., Neumann, M., Heutink, P., Synofzik, M., Wilke, C., Rissman, R. A., Slawek, J., Sitek, E., Johannsen, P., Nielsen, J. E., Ren, Y., Van Blitterswijk, M., DeJesus-Hernandez, M., Christopher, E., Murray, M. E., Bieniek, K. F., Evers, B. M., Ferrari, C., Rollinson, S., Richardson, A., Scarpini, E., Fumagalli, G. G., Padovani, A., Hardy, J., Momeni, P., Ferrari, R., Frangipane, F., Maletta, R., Anfossi, M., Gallo, M., Petrucelli, L., Suh, E. R., Lopez, O. L., Wong, T. H., van Rooij, J. G. J., Seelaar, H., Mead, S., Caselli, R. J., Reiman, E. M., Noel Sabbagh, M., Kjolby, M., Nykjaer, A., Karydas, A. M., Boxer, A. L., Grinberg, L. T., Grafman, J., Spina, S., Oblak, A., Mesulam, M. M., Weintraub, S., Geula, C., Hodges, J. R., Piguet, O., Brooks, W. S., Irwin, D. J., Trojanowski, J. Q., Lee, E. B., Josephs, K. A., Parisi, J. E., Taner, N., Knopman, D. S., Nacmias, B., Piaceri, I., Bagnoli, S., Sorbi, S., Gearing, M., Glass, J., Beach, T. G., Black, S. E., Masellis, M., Rogaeva, E., Vonsattel, J. P., Honig, L. S., Kofler, J., Bruni, A. C., Snowden, J., Mann, D., Pickering-Brown, S., Diehl-Schmid, J., Winkelmann, J., Galimberti, D., Graff, C., Öijerstedt, L., Troakes, C., Al-Sarraj, S., Cruchaga, C., Cairns, N. J., Rohrer, J. D., Halliday, G. M., Kwok, J. B., van Swieten, J. C., White, C. L., Ghetti, B., Murell, J. R., Mackenzie, I. R. A., Hsiung, G. Y. R., Borroni, B., Rossi, G., Tagliavini, F., Wszolek, Z. K., Petersen, R. C., Bigio, E. H., Grossman, M., Van Deerlin, V. M., Seeley, W. W., Miller, B. L., Graff Radford, N. R., Boeve, B. F., Dickson, D. W., Biernacka, J. M. & Rademakers, R. V., Jun 1 2018, In : The Lancet Neurology. 17, 6, p. 548-558 11 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Inborn Genetic Diseases
Genome-Wide Association Study
Age of Onset
Meta-Analysis

Relationships between lewy and tau pathologies in 375 consecutive non-Alzheimer's olfactory bulbs

Kasanuki, K., Ross, O. A., Deture, M., Walton, R. L., Sanchez-Contreras, M., Koga, S., Murray, M. E., Rademakers, R. V. & Dickson, D. W., Jan 1 2018, (Accepted/In press) In : Movement Disorders.

Research output: Contribution to journalArticle

Lewy Body Disease
alpha-Synuclein
Olfactory Bulb
Immunohistochemistry
Pathology
13 Citations (Scopus)

Sex and age interact to determine clinicopathologic differences in Alzheimer’s disease

Liesinger, A. M., Graff Radford, N. R., Duara, R., Carter, R. E., Hanna Al-Shaikh, F. S., Koga, S., Hinkle, K. M., DiLello, S. K., Johnson, M. K. F., Aziz, A., Taner, N., Ross, O. A., Dickson, D. W. & Murray, M. E., Jan 1 2018, (Accepted/In press) In : Acta Neuropathologica.

Research output: Contribution to journalArticle

Alzheimer Disease
Neurofibrillary Tangles
Age of Onset
Autopsy
Neurobehavioral Manifestations
5 Citations (Scopus)

Tau-negative amnestic dementia masquerading as Alzheimer disease dementia

Botha, H., Mantyh, W. G., Graff-Radford, J., Machulda, M. M., Przybelski, S. A., Wiste, H. J., Senjem, M. L., Parisi, J. E., Petersen, R. C., Murray, M. E., Boeve, B. F., Lowe, V., Knopman, D. S., Jack, C. R. J. & Jones, D. T., Mar 13 2018, In : Neurology. 90, 11, p. e940-e946

Research output: Contribution to journalArticle

Dementia
Alzheimer Disease
Amyloid
Biomarkers
Accidental Falls
3 Citations (Scopus)

TDP-43 and Alzheimer's Disease Pathologic Subtype in Non-Amnestic Alzheimer's Disease Dementia

Sahoo, A., Bejanin, A., Murray, M. E., Tosakulwong, N., Weigand, S. D., Serie, A. M., Senjem, M. L., Machulda, M. M., Parisi, J. E., Boeve, B. F., Knopman, D. S., Petersen, R. C., Dickson, D. W., Whitwell, J. L. & Josephs, K. A., Jan 1 2018, In : Journal of Alzheimer's Disease. 64, 4, p. 1227-1233 7 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Pathology
Neurofibrillary Tangles
Neocortex
Memory Disorders
21 Citations (Scopus)

The National Institute on Aging and the Alzheimer's Association Research Framework for Alzheimer's disease: Perspectives from the Research Roundtable

Knopman, D. S., Haeberlein, S. B., Carrillo, M. C., Hendrix, J. A., Kerchner, G., Margolin, R., Maruff, P., Miller, D. S., Tong, G., Tome, M. B., Murray, M. E., Nelson, P. T., Sano, M., Mattsson, N., Sultzer, D. L., Montine, T. J., Jack, C. R. J., Kolb, H., Petersen, R. C., Vemuri, P. D. & 8 others, Canniere, M. Z., Schneider, J. A., Resnick, S. M., Romano, G., van Harten, A. C., Wolk, D. A., Bain, L. J. & Siemers, E., Apr 1 2018, In : Alzheimer's and Dementia. 14, 4, p. 563-575 13 p.

Research output: Contribution to journalShort survey

National Institute on Aging (U.S.)
Alzheimer Disease
Research
Amyloid
Industry
46 Citations (Scopus)
Alzheimer Disease
Amyloid
Brain
Tauopathies
Neurofibrillary Tangles
2017
5 Citations (Scopus)

Abnormal expression of homeobox genes and transthyretin in C9ORF72 expansion carriers

Finch, N. A., Wang, X., Baker, M. C., Heckman, M. G., Gendron, T. D., Bieniek, K. F., Wuu, J., Dejesus-Hernandez, M., Brown, P. H., Chew, J., Jansen-West, K. R., Daughrity, L. M., Nicholson, A. M., Murray, M. E., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Petrucelli, L., Boeve, B. F. & 8 others, Graff Radford, N. R., Asmann, Y., Dickson, D. W., Benatar, M., Bowser, R., Boylan, K. B., Rademakers, R. V. & Van Blitterswijk, M., Jan 1 2017, In : Neurology: Genetics. 3, 4

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 9
Prealbumin
Homeobox Genes
Open Reading Frames
Up-Regulation
1 Citation (Scopus)

Amyloid PET scan: Staging beyond reading?

Chételat, G. & Murray, M. E., Jan 1 2017, In : Neurology. 89, 20, p. 2029-2030 2 p.

Research output: Contribution to journalEditorial

Amyloid
Positron-Emission Tomography
Reading
10 Citations (Scopus)

Approach to atypical Alzheimer’s disease and case studies of the major subtypes

Dickerson, B. C., McGinnis, S. M., Xia, C., Price, B. H., Atri, A., Murray, M. E., Mendez, M. F. & Wolk, D. A., Feb 15 2017, (Accepted/In press) In : CNS Spectrums. p. 1-11 11 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Phenotype
Biomarkers
Pathology
Amnesia
1 Citation (Scopus)

Brain tau deposition linked to systemic causes of death in normal elderly

Josephs, K. A., Tosakulwong, N., Weigand, S. D., Murray, M. E., Whitwell, J. L., Parisi, J. E., Dickson, D. W. & Petersen, R. C., Feb 1 2017, In : Neurobiology of Aging. 50, p. 163-166 4 p.

Research output: Contribution to journalArticle

Cause of Death
alpha-Synuclein
DNA-Binding Proteins
Brain
Amyloid beta-Peptides
18 Citations (Scopus)
Tauopathies
Frontotemporal Dementia
Chromosomes, Human, Pair 17
Microtubule-Associated Proteins
Parkinsonian Disorders