• 28618 Citations
  • 84 Scopus h-Index
1977 …2020

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2020

Diastolic Blood Pressure and Heart Rate Are Independently Associated With Mortality in Chronic Aortic Regurgitation

Yang, L. T., Pellikka, P. A., Enriquez-Sarano, M., Scott, C. G., Padang, R., Mankad, S. V., Schaff, H. V. & Michelena, H. I., Jan 7 2020, In : Journal of the American College of Cardiology. 75, 1, p. 29-39 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Mitral Regurgitation in Low-Flow, Low-Gradient Aortic Stenosis Patients Undergoing TAVR: Insights From the TOPAS-TAVI Registry

Freitas-Ferraz, A. B., Lerakis, S., Barbosa Ribeiro, H., Gilard, M., Cavalcante, J. L., Makkar, R., Herrmann, H. C., Windecker, S., Enriquez-Sarano, M., Cheema, A. N., Nombela-Franco, L., Amat-Santos, I., Muñoz-García, A. J., Garcia del Blanco, B., Zajarias, A., Lisko, J. C., Hayek, S., Babaliaros, V., Le Ven, F., Gleason, T. G. & 11 others, Chakravarty, T., Szeto, W. Y., Clavel, M. A., de Agustin, A., Serra, V., Schindler, J. T., Dahou, A., Annabi, M. S., Pelletier-Beaumont, E., Pibarot, P. & Rodés-Cabau, J., Mar 9 2020, In : JACC: Cardiovascular Interventions. 13, 5, p. 567-579 13 p.

Research output: Contribution to journalArticle

Mitral Valve Prolapse Patients with Less than Moderate Mitral Regurgitation Exhibit Early Cardiac Chamber Remodeling

Yang, L. T., Ahn, S. W., Li, Z., Benfari, G., Mankad, R., Takeuchi, M., Levine, R. A., Enriquez-Sarano, M. & Michelena, H. I., Jan 1 2020, (Accepted/In press) In : Journal of the American Society of Echocardiography.

Research output: Contribution to journalArticle

The bicuspid aortic valve raphe: an evolving structure

Yang, L. T., Enriquez-Sarano, M. & Michelena, H. I., May 1 2020, In : European heart journal cardiovascular Imaging. 21, 5, 1 p.

Research output: Contribution to journalArticle

2019

Atrial fibrillation is not an independent predictor of outcome in patients with aortic stenosis

Zhang, H., El-Am, E. A., Thaden, J. J., Pislaru, S. V., Scott, C. G., Krittanawong, C., Chahal, A. A., Breen, T. J., Eleid, M., Melduni, R., Greason, K. L., McCully, R. B., Sarano, M. E., Oh, J. K., Pellikka, P. & Nkomo, V. T., Jan 1 2019, (Accepted/In press) In : Heart.

Research output: Contribution to journalArticle

3 Scopus citations

AVIATOR: An open international registry to evaluate medical and surgical outcomes of aortic valve insufficiency and ascending aorta aneurysm

Aortic Valve Repair Research Network Investigators, Jun 2019, In : Journal of Thoracic and Cardiovascular Surgery. 157, 6, p. 2202-2211.e7

Research output: Contribution to journalArticle

4 Scopus citations

Burden of Tricuspid Regurgitation in Patients Diagnosed in the Community Setting

Topilsky, Y., Maltais, S., Medina Inojosa, J., Oguz, D., Michelena, H. I., Maalouf, J., Mahoney, D. W. & Sarano, M. E., Mar 1 2019, In : JACC: Cardiovascular Imaging. 12, 3, p. 433-442 10 p.

Research output: Contribution to journalArticle

37 Scopus citations

Causes and mechanisms of isolated mitral regurgitation in the community: Clinical context and outcome

Dziadzko, V., Dziadzko, M., Medina-Inojosa, J. R., Benfari, G., Michelena, H. I., Crestanello, J. A., Maalouf, J., Thapa, P. & Sarano, M. E., Jul 14 2019, In : European heart journal. 40, 27, p. 2194-2202 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Circulating Osteogenic Progenitor Cells in Mild, Moderate, and Severe Aortic Valve Stenosis

Al-Hijji, M., Narula, N., Go, J. L., Khosla, S., Sarano, M. E., Loeffler, D., Lennon, R., Lerman, L. O. & Lerman, A., Apr 1 2019, In : Mayo Clinic proceedings. 94, 4, p. 652-659 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Coexistent bicuspid aortic valve and mitral valve prolapse: Epidemiology, phenotypic spectrum, and clinical implications

Padang, R., Enriquez-Sarano, M., Pislaru, S. V., Maalouf, J. F., Nkomo, V. T., Mankad, S. V., Maltais, S., Suri, R. M., Schaff, H. V. & Michelena, H. I., Jun 1 2019, In : European heart journal cardiovascular Imaging. 20, 6, p. 677-686 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Diastolic Determinants of Excess Mortality in Heart Failure With Reduced Ejection Fraction

Benfari, G., Miller, W., Antoine, C., Rossi, A., Lin, G. D., Oh, J. K., Roger, V. L., Thapa, P. & Sarano, M. E., Sep 1 2019, In : JACC: Heart Failure. 7, 9, p. 808-817 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Excess Mortality Associated With Functional Tricuspid Regurgitation Complicating Heart Failure With Reduced Ejection Fraction

Benfari, G., Antoine, C., Miller, W., Thapa, P., Topilsky, Y., Rossi, A., Michelena, H. I., Pislaru, S. & Sarano, M. E., Jul 16 2019, In : Circulation. 140, 3, p. 196-206 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Galectin-3 Levels and Outcomes After Myocardial Infarction: A Population-Based Study

Asleh, R., Enriquez-Sarano, M., Jaffe, A. S., Manemann, S. M., Weston, S. A., Jiang, R. & Roger, V. L., May 14 2019, In : Journal of the American College of Cardiology. 73, 18, p. 2286-2295 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Long-Term Implications of Atrial Fibrillation in Patients With Degenerative Mitral Regurgitation

MIDA Investigators, Jan 29 2019, In : Journal of the American College of Cardiology. 73, 3, p. 264-274 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Outcomes from Transcatheter Aortic Valve Replacement in Patients with Low-Flow, Low-Gradient Aortic Stenosis and Left Ventricular Ejection Fraction Less Than 30%: A Substudy from the TOPAS-TAVI Registry

Maes, F., Lerakis, S., Barbosa Ribeiro, H., Gilard, M., Cavalcante, J. L., Makkar, R., Herrmann, H. C., Windecker, S., Enriquez-Sarano, M., Cheema, A. N., Nombela-Franco, L., Amat-Santos, I., Muñoz-García, A. J., Garcia Del Blanco, B., Zajarias, A., Lisko, J. C., Hayek, S., Babaliaros, V., Le Ven, F., Gleason, T. G. & 13 others, Chakravarty, T., Szeto, W., Clavel, M. A., De Agustin, A., Serra, V., Schindler, J. T., Dahou, A., Salah-Annabi, M., Pelletier-Beaumont, E., Côté, M., Puri, R., Pibarot, P. & Rodés-Cabau, J., Jan 2019, In : JAMA cardiology. 4, 1, p. 64-70 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Outcomes in Chronic Hemodynamically Significant Aortic Regurgitation and Limitations of Current Guidelines

Yang, L. T., Michelena, H. I., Scott, C. G., Sarano, M. E., Pislaru, S. V., Schaff, H. V. & Pellikka, P., Apr 16 2019, In : Journal of the American College of Cardiology. 73, 14, p. 1741-1752 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

Predictors of Progression in Patients With Stage B Aortic Regurgitation

Yang, L. T., Enriquez-Sarano, M., Michelena, H. I., Nkomo, V. T., Scott, C. G., Bailey, K. R., Oguz, D., Wajih Ullah, M. & Pellikka, P. A., Nov 19 2019, In : Journal of the American College of Cardiology. 74, 20, p. 2480-2492 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Prognostic Implications of Left Atrial Enlargement in Degenerative Mitral Regurgitation

Essayagh, B., Antoine, C., Benfari, G., Messika-Zeitoun, D., Michelena, H., Le Tourneau, T., Mankad, S., Tribouilloy, C. M., Thapa, P. & Enriquez-Sarano, M., Aug 20 2019, In : Journal of the American College of Cardiology. 74, 7, p. 858-870 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Screening for cardiac contractile dysfunction using an artificial intelligence–enabled electrocardiogram

Attia, Z. I., Kapa, S., Lopez-Jimenez, F., McKie, P. M., Ladewig, D. J., Satam, G., Pellikka, P. A., Enriquez-Sarano, M., Noseworthy, P. A., Munger, T. M., Asirvatham, S. J., Scott, C. G., Carter, R. E. & Friedman, P. A., Jan 1 2019, In : Nature Medicine. 25, 1, p. 70-74 5 p.

Research output: Contribution to journalArticle

57 Scopus citations

The unique mechanism of functional mitral regurgitation in acute myocardial infarction: A prospective dynamic 4D quantitative echocardiographic study

Kimura, T., Roger, V. L., Watanabe, N., Barros-Gomes, S., Topilsky, Y., Nishino, S., Shibata, Y. & Enriquez-Sarano, M., Apr 1 2019, In : European heart journal cardiovascular Imaging. 20, 4, p. 396-406 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Transcatheter Versus Medical Treatment of Patients With Symptomatic Severe Tricuspid Regurgitation

Taramasso, M., Benfari, G., van der Bijl, P., Alessandrini, H., Attinger-Toller, A., Biasco, L., Lurz, P., Braun, D., Brochet, E., Connelly, K. A., de Bruijn, S., Denti, P., Deuschl, F., Estevez-Loureiro, R., Fam, N., Frerker, C., Gavazzoni, M., Hausleiter, J., Ho, E., Juliard, J. M. & 38 others, Kaple, R., Besler, C., Kodali, S., Kreidel, F., Kuck, K. H., Latib, A., Lauten, A., Monivas, V., Mehr, M., Muntané-Carol, G., Nazif, T., Nickening, G., Pedrazzini, G., Philippon, F., Pozzoli, A., Praz, F., Puri, R., Rodés-Cabau, J., Schäfer, U., Schofer, J., Sievert, H., Tang, G. H. L., Thiele, H., Topilsky, Y., Rommel, K. P., Delgado, V., Vahanian, A., Von Bardeleben, R. S., Webb, J. G., Weber, M., Windecker, S., Winkel, M., Zuber, M., Leon, M. B., Hahn, R. T., Bax, J. J., Enriquez-Sarano, M. & Maisano, F., Dec 17 2019, In : Journal of the American College of Cardiology. 74, 24, p. 2998-3008 11 p.

Research output: Contribution to journalArticle

Treatment of Functional Mitral Regurgitation

Sarano, M. E., Michelena, H. I. & Grigioni, F., May 14 2019, In : Circulation. 139, 20, p. 2289-2291 3 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Clinical Outcome of Degenerative Mitral Regurgitation

Antoine, C., Benfari, G., Michelena, H. I., Maalouf, J. F., Nkomo, V. T., Thapa, P. & Sarano, M. E., Sep 25 2018, In : Circulation. 138, 13, p. 1317-1326 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Clinical presentation and outcome of tricuspid regurgitation in patients with systolic dysfunction

Topilsky, Y., Inojosa, J. M., Benfari, G., Vaturi, O., Maltais, S., Michelena, H. I., Mankad, S. & Sarano, M. E., Oct 14 2018, In : European Heart Journal. 39, 39, p. 3584-3592 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Common phenotype in patients with mitral valve prolapse who experienced sudden cardiac death

Hourdain, J., Clavel, M. A., Deharo, J. C., Asirvatham, S., Avierinos, J. F., Habib, G., Franceschi, F., Probst, V., Sadoul, N., Martins, R., Leclercq, C., Chauvin, M., Pasquie, J. L., Maury, P., Laurent, G., Ackerman, M., Hodge, D. O. & Enriquez-Sarano, M., Jan 1 2018, In : Circulation. 138, 10, p. 1067-1069 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Comparative study of bicuspid vs. tricuspid aortic valve stenosis

Huntley, G. D., Thaden, J. J., Alsidawi, S., Michelena, H. I., Maleszewski, J., Edwards, W. D., Scott, C. G., Pislaru, S. V., Pellikka, P., Greason, K. L., Ammash, N. M., Malouf, J. F., Sarano, M. E. & Nkomo, V. T., Jan 1 2018, In : European Heart Journal Cardiovascular Imaging. 19, 1, p. 3-8 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Concomitant mitral regurgitation and aortic stenosis: One step further to low-flow preserved ejection fraction aortic stenosis

Benfari, G., Clavel, M. A., Nistri, S., Maffeis, C., Vassanelli, C., Sarano, M. E. & Rossi, A., May 1 2018, In : European Heart Journal Cardiovascular Imaging. 19, 5, p. 569-573 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Dobutamine Stress Echocardiography for Management of Low-Flow, Low-Gradient Aortic Stenosis

Annabi, M. S., Touboul, E., Dahou, A., Burwash, I. G., Bergler-Klein, J., Enriquez-Sarano, M., Orwat, S., Baumgartner, H., Mascherbauer, J., Mundigler, G., Cavalcante, J. L., Larose, É., Pibarot, P. & Clavel, M. A., Feb 6 2018, In : Journal of the American College of Cardiology. 71, 5, p. 475-485 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Low-Gradient Aortic Stenosis: Solving the Conundrum Using Multi-Modality Imaging

Messika-Zeitoun, D., Oh, J. K., Topilsky, Y., Burwash, I. G., Michelena, H. I. & Sarano, M. E., Jan 1 2018, (Accepted/In press) In : Progress in Cardiovascular Diseases.

Research output: Contribution to journalArticle

1 Scopus citations

Mitral Effective Regurgitant Orifice Area Predicts Pulmonary Artery Pressure Level in Patients with Aortic Valve Stenosis

Benfari, G., Nistri, S., Faggiano, P., Clavel, M. A., Maffeis, C., Sarano, M. E., Vassanelli, C. & Rossi, A., Jan 1 2018, (Accepted/In press) In : Journal of the American Society of Echocardiography.

Research output: Contribution to journalArticle

1 Scopus citations

Outcome and undertreatment of mitral regurgitation: a community cohort study

Dziadzko, V., Clavel, M. A., Dziadzko, M., Medina-Inojosa, J. R., Michelena, H. I., Maalouf, J., Nkomo, V. T., Thapa, P. & Sarano, M. E., Mar 10 2018, In : The Lancet. 391, 10124, p. 960-969 10 p.

Research output: Contribution to journalArticle

46 Scopus citations

Standardized Definition of Structural Valve Degeneration for Surgical and Transcatheter Bioprosthetic Aortic Valves

Dvir, D., Bourguignon, T., Otto, C. M., Hahn, R. T., Rosenhek, R., Webb, J. G., Treede, H., Sarano, M. E., Feldman, T., Wijeysundera, H. C., Topilsky, Y., Aupart, M., Reardon, M. J., Mackensen, G. B., Szeto, W. Y., Kornowski, R., Gammie, J. S., Yoganathan, A. P., Arbel, Y., Borger, M. A. & 13 others, Simonato, M., Reisman, M., Makkar, R. R., Abizaid, A., McCabe, J. M., Dahle, G., Aldea, G. S., Leipsic, J., Pibarot, P., Moat, N. E., Mack, M. J., Kappetein, A. P. & Leon, M. B., Jan 23 2018, In : Circulation. 137, 4, p. 388-399 12 p.

Research output: Contribution to journalArticle

84 Scopus citations

The Bicuspid Aortic Valve Condition: The Critical Role of Echocardiography and the Case for a Standard Nomenclature Consensus

Michelena, H. I., Chandrasekaran, K., Topilsky, Y., Messika-Zeitoun, D., Della Corte, A., Evangelista, A., Schäfers, H. J. & Sarano, M. E., Jan 1 2018, (Accepted/In press) In : Progress in Cardiovascular Diseases.

Research output: Contribution to journalArticle

1 Scopus citations

The MIDA Mortality Risk Score: Development and external validation of a prognostic model for early and late death in degenerative mitral regurgitation

Grigioni, F., Clavel, M. A., Vanoverschelde, J. L., Tribouilloy, C., Pizarro, R., Huebner, M., Avierinos, J. F., Barbieri, A., Suri, R., Pasquet, A., Rusinaru, D., Gargiulo, G. D., Oberti, P., Thdron, A., Bursi, F., Michelena, H. I., Lazam, S., Szymanski, C., Nkomo, V. T., Schumacher, M. & 2 others, Bacchi-Reggiani, L. & Sarano, M. E., Apr 14 2018, In : European Heart Journal. 39, 15, p. 1281-1291 11 p.

Research output: Contribution to journalArticle

12 Scopus citations
5 Scopus citations

Transcatheter Aortic Valve Replacement in Patients With Low-Flow, Low-Gradient Aortic Stenosis: The TOPAS-TAVI Registry

Ribeiro, H. B., Lerakis, S., Gilard, M., Cavalcante, J. L., Makkar, R., Herrmann, H. C., Windecker, S., Enriquez-Sarano, M., Cheema, A. N., Nombela-Franco, L., Amat-Santos, I., Muñoz-García, A. J., Garcia del Blanco, B., Zajarias, A., Lisko, J. C., Hayek, S., Babaliaros, V., Le Ven, F., Gleason, T. G., Chakravarty, T. & 11 others, Szeto, W. Y., Clavel, M. A., de Agustin, A., Serra, V., Schindler, J. T., Dahou, A., Puri, R., Pelletier-Beaumont, E., Côté, M., Pibarot, P. & Rodés-Cabau, J., Mar 27 2018, In : Journal of the American College of Cardiology. 71, 12, p. 1297-1308 12 p.

Research output: Contribution to journalArticle

42 Scopus citations
2017
9 Scopus citations

Echocardiographic approaches and protocols for comprehensive phenotypic characterization of valvular heart disease in mice

Casaclang-Verzosa, G., Sarano, M. E., Villaraga, H. R. & Miller, J. D., Feb 14 2017, In : Journal of Visualized Experiments. 2017, 120, e54110.

Research output: Contribution to journalArticle

3 Scopus citations
7 Scopus citations

Medulla Oblongata Hemorrhage and Reverse Takotsubo Cardiomyopathy

Gobeske, K. T., Sarano, M. E., Fugate, J. E. & Wijdicks, E. F., Dec 19 2017, (Accepted/In press) In : Neurocritical Care. p. 1-4 4 p.

Research output: Contribution to journalArticle

1 Scopus citations
7 Scopus citations

Mitral Regurgitation and Increased Risk of All-Cause and Cardiovascular Mortality in Patients with Type 2 Diabetes

Rossi, A., Zoppini, G., Benfari, G., Geremia, G., Bonapace, S., Bonora, E., Vassanelli, C., Sarano, M. E. & Targher, G., Jan 1 2017, In : American Journal of Medicine. 130, 1, p. 70-76.e1

Research output: Contribution to journalArticle

10 Scopus citations

Mitral Regurgitation in the 21st Century

Sarano, M. E. & Michelena, H. I., Jan 1 2017, (Accepted/In press) In : Progress in Cardiovascular Diseases.

Research output: Contribution to journalArticle

3 Scopus citations

Prognostic Value of Soluble ST2 After Myocardial Infarction: A Community Perspective

Jenkins, W. S., Roger, V. L., Jaffe, A. S., Weston, S. A., Abou Ezzeddine, O., Jiang, R., Manemann, S. M. & Sarano, M. E., 2017, (Accepted/In press) In : American Journal of Medicine.

Research output: Contribution to journalArticle

22 Scopus citations

Recommendations for Noninvasive Evaluation of Native Valvular Regurgitation: A Report from the American Society of Echocardiography Developed in Collaboration with the Society for Cardiovascular Magnetic Resonance

Zoghbi, W. A., Adams, D., Bonow, R. O., Enriquez-Sarano, M., Foster, E., Grayburn, P. A., Hahn, R. T., Han, Y., Hung, J., Lang, R. M., Little, S. H., Shah, D. J., Shernan, S., Thavendiranathan, P., Thomas, J. D. & Weissman, N. J., Apr 1 2017, In : Journal of the American Society of Echocardiography. 30, 4, p. 303-371 69 p.

Research output: Contribution to journalArticle

531 Scopus citations

Transthoracic Echocardiography versus Computed Tomography for Ascending Aortic Measurements in Patients with Bicuspid Aortic Valve

Park, J. Y., Foley, T. A., Bonnichsen, C. R., Maurer, M. J., Goergen, K. M., Nkomo, V. T., Sarano, M. E., Williamson, E. E. & Michelena, H. I., 2017, (Accepted/In press) In : Journal of the American Society of Echocardiography.

Research output: Contribution to journalArticle

17 Scopus citations

Twenty-Year Outcome after Mitral Repair Versus Replacement for Severe Degenerative Mitral Regurgitation: Analysis of a Large, Prospective, Multicenter, International Registry

Lazam, S., Vanoverschelde, J. L., Tribouilloy, C., Grigioni, F., Suri, R. M., Avierinos, J. F., Meester, C. D., Barbieri, A., Rusinaru, D., Russo, A., Pasquet, A., Michelena, H. I., Huebner, M., Maalouf, J., Clavel, M. A., Szymanski, C. & Enriquez-Sarano, M., Jan 31 2017, In : Circulation. 135, 5, p. 410-422 13 p.

Research output: Contribution to journalArticle

56 Scopus citations
2016

Association of B-Type Natriuretic Peptide With Survival in Patients With Degenerative Mitral Regurgitation

Clavel, M. A., Tribouilloy, C., Vanoverschelde, J. L., Pizarro, R., Suri, R. M., Szymanski, C., Lazam, S., Oberti, P., Michelena, H. I., Jaffe, A. S. & Sarano, M. E., Sep 20 2016, In : Journal of the American College of Cardiology. 68, 12, p. 1297-1307 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Atherosclerotic burden and heart failure after myocardial infarction

Gerber, Y., Weston, S. A., Sarano, M. E., Manemann, S. M., Chamberlain, A., Jiang, R. & Roger, V. L., May 1 2016, In : JAMA Cardiology. 1, 2, p. 156-162 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Comprehensive Imaging in Women with Organic Mitral Regurgitation Implications for Clinical Outcome

Mantovani, F., Clavel, M. A., Michelena, H. I., Suri, R. M., Schaff, H. V. & Sarano, M. E., Apr 1 2016, In : JACC: Cardiovascular Imaging. 9, 4, p. 388-396 9 p.

Research output: Contribution to journalArticle

12 Scopus citations