• 28220 Citations
  • 83 Scopus h-Index
1977 …2020

Research output per year

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Research Output

2020

Can Aortic Regurgitation Evolve into Aortic Stenosis? New Insights on Mixed Aortic Valve Disease

Yang, L. T., Pellikka, P. A., Enriquez-Sarano, M., Luis, S. A., Padang, R., Daniels, B. K., Scott, C. G. & Michelena, H. I., Mar 2020, In : Journal of the American Society of Echocardiography. 33, 3, p. 406-408 3 p.

Research output: Contribution to journalLetter

Open Access

Diastolic Blood Pressure and Heart Rate Are Independently Associated With Mortality in Chronic Aortic Regurgitation

Yang, L. T., Pellikka, P. A., Enriquez-Sarano, M., Scott, C. G., Padang, R., Mankad, S. V., Schaff, H. V. & Michelena, H. I., Jan 7 2020, In : Journal of the American College of Cardiology. 75, 1, p. 29-39 11 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Anatomic Characterization of the Aortic Root in Patients With Bicuspid and Tricuspid Aortic Valve Stenosis: Does Fusion of Doppler-Echocardiography and Computed Tomography Resolve Discordant Severity Grading?

Arangalage, D., Laredo, M., Ou, P., Brochet, E., Cimadevilla, C., Sarano, M. E., Vahanian, A. & Messika-Zeitoun, D., Jan 1 2019, In : JACC: Cardiovascular Imaging. 12, 1, p. 210-212 3 p.

Research output: Contribution to journalLetter

6 Scopus citations

Aortic Valve Surgery in Nonelderly Patients: Insights Gained From AVIATOR

Aortic Valve Repair Research Network Investigators from the Heart Valve Society, Collaborators, Dec 1 2019, In : Seminars in thoracic and cardiovascular surgery. 31, 4, p. 643-649 7 p.

Research output: Contribution to journalReview article

Atrial fibrillation is not an independent predictor of outcome in patients with aortic stenosis

Zhang, H., El-Am, E. A., Thaden, J. J., Pislaru, S. V., Scott, C. G., Krittanawong, C., Chahal, A. A., Breen, T. J., Eleid, M., Melduni, R., Greason, K. L., McCully, R. B., Sarano, M. E., Oh, J. K., Pellikka, P. & Nkomo, V. T., Jan 1 2019, (Accepted/In press) In : Heart.

Research output: Contribution to journalArticle

1 Scopus citations

Burden of Tricuspid Regurgitation in Patients Diagnosed in the Community Setting

Topilsky, Y., Maltais, S., Medina Inojosa, J., Oguz, D., Michelena, H. I., Maalouf, J., Mahoney, D. W. & Sarano, M. E., Mar 1 2019, In : JACC: Cardiovascular Imaging. 12, 3, p. 433-442 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Causes and mechanisms of isolated mitral regurgitation in the community: Clinical context and outcome

Dziadzko, V., Dziadzko, M., Medina-Inojosa, J. R., Benfari, G., Michelena, H. I., Crestanello, J. A., Maalouf, J., Thapa, P. & Sarano, M. E., Jul 14 2019, In : European heart journal. 40, 27, p. 2194-2202 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Circulating Osteogenic Progenitor Cells in Mild, Moderate, and Severe Aortic Valve Stenosis

Al-Hijji, M., Narula, N., Go, J. L., Khosla, S., Sarano, M. E., Loeffler, D., Lennon, R., Lerman, L. O. & Lerman, A., Apr 1 2019, In : Mayo Clinic proceedings. 94, 4, p. 652-659 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Coexistent bicuspid aortic valve and mitral valve prolapse: epidemiology, phenotypic spectrum, and clinical implications

Padang, R., Sarano, M. E., Pislaru, S. V., Maalouf, J. F., Nkomo, V. T., Mankad, S. V., Maltais, S., Suri, R. M., Schaff, H. V. & Michelena, H. I., Jun 1 2019, In : European heart journal cardiovascular Imaging. 20, 6, p. 677-686 10 p.

Research output: Contribution to journalArticle

Diastolic Determinants of Excess Mortality in Heart Failure With Reduced Ejection Fraction

Benfari, G., Miller, W., Antoine, C., Rossi, A., Lin, G. D., Oh, J. K., Roger, V. L., Thapa, P. & Sarano, M. E., Sep 1 2019, In : JACC: Heart Failure. 7, 9, p. 808-817 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Excess Mortality Associated With Functional Tricuspid Regurgitation Complicating Heart Failure With Reduced Ejection Fraction

Benfari, G., Antoine, C., Miller, W., Thapa, P., Topilsky, Y., Rossi, A., Michelena, H. I., Pislaru, S. & Sarano, M. E., Jul 16 2019, In : Circulation. 140, 3, p. 196-206 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Galectin-3 Levels and Outcomes After Myocardial Infarction: A Population-Based Study

Asleh, R., Sarano, M. E., Jaffe, A. S., Manemann, S. M., Weston, S. A., Jiang, R. & Roger, V. L., May 14 2019, In : Journal of the American College of Cardiology. 73, 18, p. 2286-2295 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

How Should Very Severe Aortic Stenosis Be Defined in Asymptomatic Individuals?

Tribouilloy, C., Rusinaru, D., Bohbot, Y., Maréchaux, S., Vanoverschelde, J. L. & Sarano, M. E., Feb 5 2019, In : Journal of the American Heart Association. 8, 3, p. e011724

Research output: Contribution to journalEditorial

Open Access
2 Scopus citations

Long-Term Implications of Atrial Fibrillation in Patients With Degenerative Mitral Regurgitation

MIDA Investigators, Jan 29 2019, In : Journal of the American College of Cardiology. 73, 3, p. 264-274 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Morphologic Types of Tricuspid Regurgitation: Characteristics and Prognostic Implications

Prihadi, E. A., Delgado, V., Leon, M. B., Sarano, M. E., Topilsky, Y. & Bax, J. J., Mar 1 2019, In : JACC: Cardiovascular Imaging. 12, 3, p. 491-499 9 p.

Research output: Contribution to journalReview article

6 Scopus citations

Outcomes from Transcatheter Aortic Valve Replacement in Patients with Low-Flow, Low-Gradient Aortic Stenosis and Left Ventricular Ejection Fraction Less Than 30%: A Substudy from the TOPAS-TAVI Registry

Maes, F., Lerakis, S., Barbosa Ribeiro, H., Gilard, M., Cavalcante, J. L., Makkar, R., Herrmann, H. C., Windecker, S., Sarano, M. E., Cheema, A. N., Nombela-Franco, L., Amat-Santos, I., Muñoz-García, A. J., Garcia Del Blanco, B., Zajarias, A., Lisko, J. C., Hayek, S., Babaliaros, V., Le Ven, F., Gleason, T. G. & 13 others, Chakravarty, T., Szeto, W., Clavel, M. A., De Agustin, A., Serra, V., Schindler, J. T., Dahou, A., Salah-Annabi, M., Pelletier-Beaumont, E., Côté, M., Puri, R., Pibarot, P. & Rodés-Cabau, J., Jan 1 2019, In : JAMA Cardiology. 4, 1, p. 64-70 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Outcomes in Chronic Hemodynamically Significant Aortic Regurgitation and Limitations of Current Guidelines

Yang, L. T., Michelena, H. I., Scott, C. G., Sarano, M. E., Pislaru, S. V., Schaff, H. V. & Pellikka, P., Apr 16 2019, In : Journal of the American College of Cardiology. 73, 14, p. 1741-1752 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Predictors of Progression in Patients With Stage B Aortic Regurgitation

Yang, L. T., Enriquez-Sarano, M., Michelena, H. I., Nkomo, V. T., Scott, C. G., Bailey, K. R., Oguz, D., Wajih Ullah, M. & Pellikka, P. A., Nov 19 2019, In : Journal of the American College of Cardiology. 74, 20, p. 2480-2492 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Prognostic Implications of Left Atrial Enlargement in Degenerative Mitral Regurgitation

Essayagh, B., Antoine, C., Benfari, G., Messika-Zeitoun, D., Michelena, H. I., Le Tourneau, T., Mankad, S., Tribouilloy, C. M., Thapa, P. & Sarano, M. E., Aug 20 2019, In : Journal of the American College of Cardiology. 74, 7, p. 858-870 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Screening for cardiac contractile dysfunction using an artificial intelligence–enabled electrocardiogram

Attia, Z. I., Kapa, S., Lopez-Jimenez, F., McKie, P., Ladewig, D. J., Satam, G., Pellikka, P., Sarano, M. E., Noseworthy, P., Munger, T. M., Asirvatham, S. J., Scott, C. G., Carter, R. E. & Friedman, P. A., Jan 1 2019, In : Nature Medicine. 25, 1, p. 70-74 5 p.

Research output: Contribution to journalLetter

47 Scopus citations

Sex-Related Differences in Low-Gradient, Low–Ejection Fraction Aortic Stenosis: Results From the Multicenter TOPAS Study

Bartko, P. E., Clavel, M. A., Annabi, M. S., Dahou, A., Ristl, R., Goliasch, G., Baumgartner, H., Hengstenberg, C., Cavalcante, J. L., Burwash, I., Sarano, M. E., Bergler-Klein, J., Rodés-Cabau, J., Pibarot, P. & Mascherbauer, J., Jan 1 2019, In : JACC: Cardiovascular Imaging. 12, 1, p. 203-205 3 p.

Research output: Contribution to journalLetter

2 Scopus citations

The AVIATOR registry: The importance of evaluating long-term patient outcomes

On behalf of the Aortic Valve Repair Research Network Investigators, May 1 2019, In : Annals of Cardiothoracic Surgery. 8, 3, p. 393-395 3 p.

Research output: Contribution to journalEditorial

Open Access

The unique mechanism of functional mitral regurgitation in acute myocardial infarction: A prospective dynamic 4D quantitative echocardiographic study

Kimura, T., Roger, V. L., Watanabe, N., Barros-Gomes, S., Topilsky, Y., Nishino, S., Shibata, Y. & Sarano, M. E., Apr 1 2019, In : European heart journal cardiovascular Imaging. 20, 4, p. 396-406 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Treatment of Functional Mitral Regurgitation

Sarano, M. E., Michelena, H. I. & Grigioni, F., May 14 2019, In : Circulation. 139, 20, p. 2289-2291 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Tricuspid regurgitation is a public health crisis

Enriquez-Sarano, M., Messika-Zeitoun, D., Topilsky, Y., Tribouilloy, C., Benfari, G. & Michelena, H., Jan 1 2019, (Accepted/In press) In : Progress in Cardiovascular Diseases.

Research output: Contribution to journalReview article

2 Scopus citations
2018

AVIATOR: An open international registry to evaluate medical and surgical outcomes of aortic valve insufficiency and ascending aorta aneurysm

Aortic Valve Repair Research Network Investigators, Jan 1 2018, (Accepted/In press) In : Journal of Thoracic and Cardiovascular Surgery.

Research output: Contribution to journalArticle

4 Scopus citations

Clinical Outcome of Degenerative Mitral Regurgitation

Antoine, C., Benfari, G., Michelena, H. I., Maalouf, J. F., Nkomo, V. T., Thapa, P. & Sarano, M. E., Sep 25 2018, In : Circulation. 138, 13, p. 1317-1326 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Clinical presentation and outcome of tricuspid regurgitation in patients with systolic dysfunction

Topilsky, Y., Inojosa, J. M., Benfari, G., Vaturi, O., Maltais, S., Michelena, H. I., Mankad, S. & Sarano, M. E., Oct 14 2018, In : European Heart Journal. 39, 39, p. 3584-3592 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Common Phenotype in Patients With Mitral Valve Prolapse Who Experienced Sudden Cardiac Death

Hourdain, J., Clavel, M. A., Deharo, J. C., Asirvatham, S. J., Avierinos, J. F., Habib, G., Franceschi, F., Probst, V., Sadoul, N., Martins, R., Leclercq, C., Chauvin, M., Pasquie, J. L., Maury, P., Laurent, G., Ackerman, M. J., Hodge, D. O. & Sarano, M. E., Sep 4 2018, In : Circulation. 138, 10, p. 1067-1069 3 p.

Research output: Contribution to journalLetter

3 Scopus citations

Comparative study of bicuspid vs. tricuspid aortic valve stenosis

Huntley, G. D., Thaden, J. J., Alsidawi, S., Michelena, H. I., Maleszewski, J., Edwards, W. D., Scott, C. G., Pislaru, S. V., Pellikka, P., Greason, K. L., Ammash, N. M., Malouf, J. F., Sarano, M. E. & Nkomo, V. T., Jan 1 2018, In : European Heart Journal Cardiovascular Imaging. 19, 1, p. 3-8 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Concomitant mitral regurgitation and aortic stenosis: One step further to low-flow preserved ejection fraction aortic stenosis

Benfari, G., Clavel, M. A., Nistri, S., Maffeis, C., Vassanelli, C., Sarano, M. E. & Rossi, A., May 1 2018, In : European Heart Journal Cardiovascular Imaging. 19, 5, p. 569-573 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Corrigan's pulse and Quincke's pulse

Sacks, C. A., Michelena, H. I. & Sarano, M. E., Aug 2 2018, In : New England Journal of Medicine. 379, 5, p. e9

Research output: Contribution to journalComment/debate

2 Scopus citations

Dobutamine Stress Echocardiography for Management of Low-Flow, Low-Gradient Aortic Stenosis

Annabi, M. S., Touboul, E., Dahou, A., Burwash, I. G., Bergler-Klein, J., Sarano, M. E., Orwat, S., Baumgartner, H., Mascherbauer, J., Mundigler, G., Cavalcante, J. L., Larose, É., Pibarot, P. & Clavel, M. A., Feb 6 2018, In : Journal of the American College of Cardiology. 71, 5, p. 475-485 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Doppler-Echocardiographic Assessment of Tricuspid Regurgitation

Topilsky, Y., Michelena, H. I., Messika-Zeitoun, D. & Sarano, M. E., Nov 1 2018, In : Progress in Cardiovascular Diseases. 61, 5-6, p. 397-403 7 p.

Research output: Contribution to journalReview article

1 Scopus citations

Low-Gradient Aortic Stenosis: Solving the Conundrum Using Multi-Modality Imaging

Messika-Zeitoun, D., Oh, J. K., Topilsky, Y., Burwash, I. G., Michelena, H. I. & Sarano, M. E., Jan 1 2018, (Accepted/In press) In : Progress in Cardiovascular Diseases.

Research output: Contribution to journalArticle

1 Scopus citations

Mitral Effective Regurgitant Orifice Area Predicts Pulmonary Artery Pressure Level in Patients with Aortic Valve Stenosis

Benfari, G., Nistri, S., Faggiano, P., Clavel, M. A., Maffeis, C., Sarano, M. E., Vassanelli, C. & Rossi, A., Jan 1 2018, (Accepted/In press) In : Journal of the American Society of Echocardiography.

Research output: Contribution to journalArticle

1 Scopus citations

Outcome and undertreatment of mitral regurgitation: a community cohort study

Dziadzko, V., Clavel, M. A., Dziadzko, M., Medina-Inojosa, J. R., Michelena, H. I., Maalouf, J., Nkomo, V. T., Thapa, P. & Sarano, M. E., Mar 10 2018, In : The Lancet. 391, 10124, p. 960-969 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Pathophysiology of Degenerative Mitral Regurgitation: New 3-Dimensional Imaging Insights

Antoine, C., Mantovani, F., Benfari, G., Mankad, S. V., Maalouf, J. F., Michelena, H. I. & Sarano, M. E., Jan 1 2018, In : Circulation. Cardiovascular imaging. 11, 1, p. e005971

Research output: Contribution to journalReview article

Open Access
9 Scopus citations

Standardized Definition of Structural Valve Degeneration for Surgical and Transcatheter Bioprosthetic Aortic Valves

Dvir, D., Bourguignon, T., Otto, C. M., Hahn, R. T., Rosenhek, R., Webb, J. G., Treede, H., Sarano, M. E., Feldman, T., Wijeysundera, H. C., Topilsky, Y., Aupart, M., Reardon, M. J., Mackensen, G. B., Szeto, W. Y., Kornowski, R., Gammie, J. S., Yoganathan, A. P., Arbel, Y., Borger, M. A. & 13 others, Simonato, M., Reisman, M., Makkar, R. R., Abizaid, A., McCabe, J. M., Dahle, G., Aldea, G. S., Leipsic, J., Pibarot, P., Moat, N. E., Mack, M. J., Kappetein, A. P. & Leon, M. B., Jan 23 2018, In : Circulation. 137, 4, p. 388-399 12 p.

Research output: Contribution to journalArticle

72 Scopus citations

The Bicuspid Aortic Valve Condition: The Critical Role of Echocardiography and the Case for a Standard Nomenclature Consensus

Michelena, H. I., Chandrasekaran, K., Topilsky, Y., Messika-Zeitoun, D., Della Corte, A., Evangelista, A., Schäfers, H. J. & Sarano, M. E., Jan 1 2018, (Accepted/In press) In : Progress in Cardiovascular Diseases.

Research output: Contribution to journalArticle

1 Scopus citations

The MIDA Mortality Risk Score: Development and external validation of a prognostic model for early and late death in degenerative mitral regurgitation

Grigioni, F., Clavel, M. A., Vanoverschelde, J. L., Tribouilloy, C., Pizarro, R., Huebner, M., Avierinos, J. F., Barbieri, A., Suri, R., Pasquet, A., Rusinaru, D., Gargiulo, G. D., Oberti, P., Thdron, A., Bursi, F., Michelena, H. I., Lazam, S., Szymanski, C., Nkomo, V. T., Schumacher, M. & 2 others, Bacchi-Reggiani, L. & Sarano, M. E., Apr 14 2018, In : European Heart Journal. 39, 15, p. 1281-1291 11 p.

Research output: Contribution to journalArticle

12 Scopus citations
5 Scopus citations

Transcatheter Aortic Valve Replacement in Patients With Low-Flow, Low-Gradient Aortic Stenosis: The TOPAS-TAVI Registry

Ribeiro, H. B., Lerakis, S., Gilard, M., Cavalcante, J. L., Makkar, R., Herrmann, H. C., Windecker, S., Sarano, M. E., Cheema, A. N., Nombela-Franco, L., Amat-Santos, I., Muñoz-García, A. J., Garcia del Blanco, B., Zajarias, A., Lisko, J. C., Hayek, S., Babaliaros, V., Le Ven, F., Gleason, T. G., Chakravarty, T. & 11 others, Szeto, W. Y., Clavel, M. A., de Agustin, A., Serra, V., Schindler, J. T., Dahou, A., Puri, R., Pelletier-Beaumont, E., Côté, M., Pibarot, P. & Rodés-Cabau, J., Mar 27 2018, In : Journal of the American College of Cardiology. 71, 12, p. 1297-1308 12 p.

Research output: Contribution to journalArticle

39 Scopus citations
2017

Competing risks need to be considered in survival analysis models for cardiovascular outcomes

Huebner, M., Wolkewitz, M., Sarano, M. E. & Schumacher, M., Jun 1 2017, In : Journal of Thoracic and Cardiovascular Surgery. 153, 6, p. 1427-1431 5 p.

Research output: Contribution to journalEditorial

5 Scopus citations
7 Scopus citations

Echocardiographic approaches and protocols for comprehensive phenotypic characterization of valvular heart disease in mice

Casaclang-Verzosa, G., Sarano, M. E., Villaraga, H. R. & Miller, J. D., Feb 14 2017, In : Journal of Visualized Experiments. 2017, 120, e54110.

Research output: Contribution to journalArticle

3 Scopus citations

High sensitivity troponin and valvular heart disease

McCarthy, C. P., Donnellan, E., Phelan, D., Griffin, B. P., Sarano, M. E. & McEvoy, J. W., Jul 1 2017, In : Trends in Cardiovascular Medicine. 27, 5, p. 326-333 8 p.

Research output: Contribution to journalReview article

3 Scopus citations

Impact of Aortic Valve Calcification and Sex on Hemodynamic Progression and Clinical Outcomes in AS

Tastet, L., Sarano, M. E., Capoulade, R., Malouf, J., Araoz, P. A., Shen, M., Michelena, H. I., Larose, É., Arsenault, M., Bédard, É., Pibarot, P. & Clavel, M. A., Apr 25 2017, In : Journal of the American College of Cardiology. 69, 16, p. 2096-2098 3 p.

Research output: Contribution to journalLetter

9 Scopus citations