Matthew Philip Goetz, MD

  • 9038 Citations
  • 45 Scopus h-Index
20022020

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2014

Aurora-A mitotic kinase induces endocrine resistance through down-regulation of ERα expression in initially ERα+ breast cancer cells

Opyrchal, M., Salisbury, J. L., Zhang, S., McCubrey, J., Hawse, J., Goetz, M. P., Lomberk, G. A., Haddad, T., Degnim, A., Lange, C., Ingle, J. N., Galanis, E. & D'Assoro, A. B., May 9 2014, In : PloS one. 9, 5, e96995.

Research output: Contribution to journalArticle

14 Scopus citations

Comparative Uterotrophic Effects of Endoxifen and Tamoxifen in Ovariectomized Sprague-Dawley Rats

Schweikart, K. M., Eldridge, S. R., Safgren, S. L., Parman, T., Reid, J. M., Ames, M. M., Goetz, M. P. & Davis, M. A., Dec 2014, In : Toxicologic Pathology. 42, 8, p. 1188-1196 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

CYP2D6 Genotype and Adjuvant Tamoxifen: Meta-Analysis of Heterogeneous Study Populations

Province, M. A., Goetz, M. P., Brauch, H., Flockhart, D. A., Hebert, J. M., Whaley, R., Suman, V. J., Schroth, W., Winter, S., Zembutsu, H., Mushiroda, T., Newman, W. G., Lee, M. T. M., Ambrosone, C. B., Beckmann, M. W., Choi, J. Y., Dieudonné, A. S., Fasching, P. A., Ferraldeschi, R., Gong, L. & 44 others, Haschke-Becher, E., Howell, A., Jordan, L. B., Hamann, U., Kiyotani, K., Krippl, P., Lambrechts, D., Latif, A., Langsenlehner, U., Lorizio, W., Neven, P., Nguyen, A. T., Park, B. W., Purdie, C. A., Quinlan, P., Renner, W., Schmidt, M., Schwab, M., Shin, J. G., Stingl, J. C., Wegman, P., Wingren, S., Wu, A. H. B., Ziv, E., Zirpoli, G., Thompson, A. M., Jordan, V. C., Nakamura, Y., Altman, R. B., Ames, M. M., Weinshilboum, R. M., Eichelbaum, M., Ingle, J. N., Klein, T. E., Boländer, J., Ulmer, H. U., Fischer-Bosch, M., Fritz, P., Simon, W., Bryan, Y., Strick, R., Koelbl, H., Ambrosone, C. A. & H, E. Z., Feb 1 2014, In : Clinical pharmacology and therapeutics. 95, 2, p. 216-227 12 p.

Research output: Contribution to journalArticle

116 Scopus citations

ERβ1: Characterization, prognosis, and evaluation of treatment strategies in ERα-positive and -negative breast cancer

Reese, J. M., Suman, V. J., Subramaniam, M., Wu, X., Negron, V., Gingery, A., Pitel, K. S., Shah, S. S., Cunliffe, H. E., McCullough, A. E., Pockaj, B. A., Couch, F. J., Olson, J. E., Reynolds, C., Lingle, W. L., Spelsberg, T. C., Goetz, M. P., Ingle, J. N. & Hawse, J. R., Oct 7 2014, In : BMC cancer. 14, 1, 749.

Research output: Contribution to journalArticle

27 Scopus citations

Estrogens and their precursors in postmenopausal women with early breast cancer receiving anastrozole

Ingle, J. N., Kalari, K. R., Buzdar, A. U., Robson, M. E., Goetz, M. P., Desta, Z., Barman, P., Dudenkov, T. T., Northfelt, D. W., Perez, E. A., Flockhart, D. A., Williard, C. V., Wang, L. M. & Weinshilboum, R. M., May 1 2014, (Accepted/In press) In : Steroids.

Research output: Contribution to journalArticle

25 Scopus citations

Inhibition of Cdk2 kinase activity selectively targets the CD44 +/CD24-/Low stem-like subpopulation and restores chemosensitivity of SUM149PT triple-negative breast cancer cells

Opyrchal, M., Salisbury, J. L., Iankov, I., Goetz, M. P., McCubrey, J., Gambino, M. W., Malatino, L., Puccia, G., Ingle, J. N., Galanis, E. & D'Assoro, A. B., Sep 2014, In : International journal of oncology. 45, 3, p. 1193-1199 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Once-daily radiation therapy for inflammatory breast cancer

Brown, L., Harmsen, W., Blanchard, M., Goetz, M., Jakub, J., Mutter, R., Petersen, I., Rooney, J., Stauder, M., Yan, E. & Laack, N., Aug 1 2014, In : International Journal of Radiation Oncology Biology Physics. 89, 5, p. 997-1003 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Pharmacokinetics of endoxifen and tamoxifen in female mice: Implications for comparative in vivo activity studies

Reid, J. M., Goetz, M. P., Buhrow, S. A., Walden, C., Safgren, S. L., Kuffel, M. J., Reinicke, K. E., Suman, V., Haluska, P., Hou, X. & Ames, M. M., Oct 9 2014, In : Cancer chemotherapy and pharmacology. 74, 6, p. 1271-1278 8 p.

Research output: Contribution to journalArticle

14 Scopus citations
16 Scopus citations

The effects of a novel hormonal breast cancer therapy, endoxifen, on the mouse skeleton

Gingery, A., Subramaniam, M., Pitel, K. S., Reese, J. M., Cicek, M., Lindenmaier, L. B., Ingle, J. N., Goetz, M. P., Turner, R. T., Iwaniec, U. T., Spelsberg, T. C. & Hawse, J. R., May 22 2014, In : PloS one. 9, 5, e98219.

Research output: Contribution to journalArticle

4 Scopus citations
2015

Activation of PI3K/Akt/mTOR signaling in the tumor stroma drives endocrine therapy-dependent breast tumor regression

Polo, M. L., Riggio, M., May, M., Rodríguez, M. J., Perrone, M. C., Stallings-Mann, M., Kaen, D., Frost, M., Goetz, M., Boughey, J., Lanari, C., Radisky, D. & Novaro, V., 2015, In : Oncotarget. 6, 26, p. 22081-22097 17 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2

Vachon, C. M., Schaid, D. J., Ingle, J. N., Wickerham, D. L., Kubo, M., Mushiroda, T., Goetz, M. P., Carlson, E. E., Paik, S., Wolmark, N., Nakamura, Y., Wang, L., Weinshilboum, R. & Couch, F. J., Jan 1 2015, In : Breast Cancer Research and Treatment. 149, 2, p. 517-523 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Breast cancer, version 1.2016 featured updates to the NCCN guidelines

Gradishar, W. J., Anderson, B. O., Balassanian, R., Blair, S. L., Burstein, H. J., Cyr, A., Elias, A. D., Farrar, W. B., Forero, A., Giordano, S. H., Goetz, M., Goldstein, L. J., Hudis, C. A., Isakoff, S. J., Marcom, P. K., Mayer, I. A., McCormick, B., Moran, M., Patel, S. A., Pierce, L. J. & 11 others, Reed, E. C., Salerno, K. E., Schwartzberg, L. S., Smith, K. L., Smith, M. L., Soliman, H., Somlo, G., Telli, M., Ward, J. H., Shead, D. A. & Kumar, R., Dec 1 2015, In : JNCCN Journal of the National Comprehensive Cancer Network. 13, 12, p. 1475-1485 11 p.

Research output: Contribution to journalArticle

Open Access
103 Scopus citations

Evaluation of CYP2D6 enzyme activity using a 13C-dextromethorphan breath test in women receiving adjuvant tamoxifen

Safgren, S. L., Suman, V. J., Kosel, M. L., Gilbert, J. A., Buhrow, S. A., Black, J. L., Northfelt, D. W., Modak, A. S., Rosen, D., Ingle, J. N., Ames, M. M., Reid, J. M. & Goetz, M. P., Mar 27 2015, In : Pharmacogenetics and genomics. 25, 4, p. 157-163 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Exome sequencing reveals frequent deleterious germline variants in cancer susceptibility genes in women with invasive breast cancer undergoing neoadjuvant chemotherapy

Ellingson, M. S., Hart, S. N., Kalari, K. R., Suman, V., Schahl, K. A., Dockter, T. J., Felten, S. J., Sinnwell, J. P., Thompson, K. J., Tang, X., Vedell, P. T., Barman, P., Sicotte, H., Eckel-Passow, J. E., Northfelt, D. W., Gray, R. J., McLaughlin, S. A., Moreno-Aspitia, A., Ingle, J. N., Moyer, A. M. & 9 others, Visscher, D. W., Jones, K., Conners, A., McDonough, M., Wieben, E. D., Wang, L., Weinshilboum, R., Boughey, J. C. & Goetz, M. P., Sep 7 2015, In : Breast Cancer Research and Treatment. 153, 2, p. 435-443 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Landscape of Neoadjuvant Therapy for Breast Cancer

Haddad, T. C. & Goetz, M. P., May 1 2015, In : Annals of Surgical Oncology. 22, 5, p. 1408-1415 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Loss of heterozygosity at the CYP2D6 locus in breast cancer: Implications for germline pharmacogenetic studies

Goetz, M. P., Sun, J. X., Suman, V. J., Silva, G. O., Perou, C. M., Nakamura, Y., Cox, N. J., Stephens, P. J., Miller, V. A., Ross, J. S., Chen, D., Safgren, S. L., Kuffel, M. J., Ames, M. M., Kalari, K. R., Gomez, H. L., Gonzalez-Angulo, A. M., Burgues, O., Brauch, H. B., Ingle, J. N. & 2 others, Ratain, M. J. & Yelensky, R., Feb 1 2015, In : Journal of the National Cancer Institute. 107, 2, dju401.

Research output: Contribution to journalArticle

34 Scopus citations

TBCRC 008: Early change in 18F-FDG uptake on PET predicts response to preoperative systemic therapy in human epidermal growth factor receptor 2-negative primary operable breast cancer

Connolly, R. M., Leal, J. P., Goetz, M. P., Zhang, Z., Zhou, X. C., Jacobs, L. K., Mhlanga, J., Joo, H. O., Carpenter, J., Storniolo, A. M., Watkins, S., Fetting, J. H., Miller, R. S., Sideras, K., Jeter, S. C., Walsh, B., Powers, P., Zorzi, J., Boughey, J. C., Davidson, N. E. & 6 others, Carey, L. A., Wolff, A. C., Khouri, N., Gabrielson, E., Wahl, R. L. & Stearns, V., Jan 1 2015, In : Journal of Nuclear Medicine. 56, 1, p. 31-37 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

Use of biomarkers to guide decisions on systemic therapy for women with metastatic breast cancer: American Society of Clinical Oncology clinical practice guideline

Van Poznak, C., Somerfield, M. R., Bast, R. C., Cristofanilli, M., Goetz, M. P., Gonzalez-Angulo, A. M., Hicks, D. G., Hill, E. G., Liu, M. C., Lucas, W., Mayer, I. A., Mennel, R. G., Symmans, W. F., Hayes, D. F. & Harris, L. N., Aug 20 2015, In : Journal of Clinical Oncology. 33, 24, p. 2695-2704 10 p.

Research output: Contribution to journalArticle

153 Scopus citations
2016

A first-in-human phase i study of the oral p38 MAPK inhibitor, ralimetinib (LY2228820 Dimesylate), in patients with advanced cancer

Patnaik, A., Haluska, P., Tolcher, A. W., Erlichman, C., Papadopoulos, K. P., Lensing, J. L., Beeram, M., Molina, J. R., Rasco, D. W., Arcos, R. R., Kelly, C. S., Wijayawardana, S. R., Zhang, X., Stancato, L. F., Bell, R., Shi, P., Kulanthaivel, P., Pitou, C., Mulle, L. B., Farrington, D. L. & 2 others, Chan, E. M. & Goetz, M. P., Mar 1 2016, In : Clinical Cancer Research. 22, 5, p. 1095-1102 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Clonal expansion of antitumor T cells in breast cancer correlates with response to neoadjuvant chemotherapy

Park, J. H., Jang, M., Tarhan, Y. E., Katagiri, T., Sasa, M., Miyoshi, Y., Kalari, K. R., Suman, V. J., Weinshilboum, R., Wang, L., Boughey, J. C., Goetz, M. P. & Nakamura, Y., Aug 2016, In : International journal of oncology. 49, 2, p. 471-478 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Estrogen, SNP-dependent chemokine expression and selective estrogen receptor modulator regulation

Ho, M. F., Bongartz, T., Liu, M., Kalari, K. R., Goss, P. E., Shepherd, L. E., Goetz, M. P., Kubo, M., Ingle, J. N., Wang, L. & Weinshilboum, R. M., Mar 2016, In : Molecular Endocrinology. 30, 3, p. 382-398 17 p.

Research output: Contribution to journalArticle

17 Scopus citations

Gene expression profiling identifies responsive patients with cancer of unknown primary treated with carboplatin, paclitaxel, and everolimus: NCCTG N0871 (alliance)

Yoon, H. H., Foster, N. R., Meyers, J. P., Steen, P. D., Visscher, D. W., Pillai, R., Prow, D. M., Reynolds, C. M., Marchello, B. T., Mowat, R. B., Mattar, B. I., Erlichman, C. & Goetz, M. P., Feb 1 2016, In : Annals of Oncology. 27, 2, p. 339-344 6 p., mdv543.

Research output: Contribution to journalArticle

18 Scopus citations

Genetic polymorphisms in the long noncoding RNA MIR2052HG offer a pharmacogenomic basis for the response of breast cancer patients to aromatase inhibitor therapy

Ingle, J. N., Xie, F., Ellis, M. J., Goss, P. E., Shepherd, L. E., Chapman, J. A. W., Chen, B. E., Kubo, M., Furukawa, Y., Momozawa, Y., Stearns, V., Pritchard, K. I., Barman, P., Carlson, E. E., Goetz, M. P., Weinshilboum, R. M., Kalari, K. R. & Wang, L., Dec 1 2016, In : Cancer research. 76, 23, p. 7012-7023 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Phase i Study of Panobinostat (LBH589) and Letrozole in Postmenopausal Metastatic Breast Cancer Patients

Tan, W., Allred, J. B., Moreno Aspitia, A., Northfelt, D. W., Ingle, J. N., Goetz, M. P. & Perez, E. A., Apr 1 2016, In : Clinical Breast Cancer. 16, 2, p. 82-86 5 p.

Research output: Contribution to journalArticle

17 Scopus citations
2017

A comprehensive analysis of breast cancer microbiota and host gene expression

Thompson, K. J., Ingle, J. N., Tang, X., Chia, N., Jeraldo, P. R., Walther-Antonio, M. R., Kandimalla, K. K., Johnson, S., Yao, J. Z., Harrington, S. C., Suman, V. J., Wang, L., Weinshilboum, R. L., Boughey, J. C., Kocher, J. P., Nelson, H., Goetz, M. P. & Kalari, K. R., Nov 2017, In : PloS one. 12, 11, e0188873.

Research output: Contribution to journalArticle

18 Scopus citations

A phase II trial of neoadjuvant MK-2206, an AKT inhibitor, with anastrozole in clinical stage II or III PIK3CA-mutant ER-positive and HER2-negative breast cancer

Ma, C. X., Suman, V., Goetz, M. P., Northfelt, D., Burkard, M. E., Ademuyiwa, F., Naughton, M., Margenthaler, J., Aft, R., Gray, R., Tevaarwerk, A., Wilke, L., Haddad, T., Moynihan, T., Loprinzi, C., Hieken, T., Barnell, E. K., Skidmore, Z. L., Feng, Y. Y., Krysiak, K. & 14 others, Hoog, J., Guo, Z., Nehring, L., Wisinski, K. B., Mardis, E., Hagemann, I. S., Vij, K., Sanati, S., Al-Kateb, H., Griffith, O. L., Griffith, M., Doyle, L., Erlichman, C. & Ellis, M. J., Nov 15 2017, In : Clinical Cancer Research. 23, 22, p. 6823-6832 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

A phase I study of cilengitide and paclitaxel in patients with advanced solid tumors

Haddad, T., Qin, R., Lupu, R., Satele, D., Eadens, M., Goetz, M. P., Erlichman, C. & Molina, J., Jun 1 2017, In : Cancer Chemotherapy and Pharmacology. 79, 6, p. 1221-1227 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1

Liu, T., Yu, J., Deng, M., Yin, Y., Zhang, H., Luo, K., Qin, B., Li, Y., Wu, C., Ren, T., Han, Y., Yin, P., Kim, J. J., Lee, S. B., Lin, J., Zhang, L., Zhang, J., Nowsheen, S., Wang, L., Boughey, J. & 3 others, Goetz, M. P., Yuan, J. & Lou, Z., Jan 9 2017, In : Nature communications. 8, 13923.

Research output: Contribution to journalArticle

52 Scopus citations

Efficacy of the PARP inhibitor veliparib with carboplatin or as a single agent in patients with germline BRCA1- or BRCA2-associated metastatic breast cancer: California Cancer Consortium trial NCT01149083

Somlo, G., Frankel, P. H., Arun, B. K., Ma, C. X., Garcia, A. A., Cigler, T., Cream, L. V., Harvey, H. A., Sparano, J. A., Nanda, R., Chew, H. K., Moynihan, T. J., Vahdat, L. T., Goetz, M. P., Beumer, J. H., Hurria, A., Mortimer, J., Piekarz, R., Sand, S., Herzog, J. & 7 others, Van Tongeren, L. R., Ferry-Galow, K. V., Chen, A. P., Ruel, C., Newman, E. M., Gandara, D. R. & Weitzel, J. N., Aug 1 2017, In : Clinical Cancer Research. 23, 15, p. 4066-4076 11 p.

Research output: Contribution to journalArticle

42 Scopus citations

ERβ inhibits cyclin dependent kinases 1 and 7 in triple negative breast cancer

Reese, J. M., Bruinsma, E. S., Monroe, D. G., Negron, V., Suman, V. J., Ingle, J. N., Goetz, M. P. & Hawse, J. R., 2017, In : Oncotarget. 8, 57, p. 96506-96521 16 p.

Research output: Contribution to journalArticle

9 Scopus citations

Establishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer study

Yu, J., Qin, B., Moyer, A. M., Sinnwell, J. P., Thompson, K. J., Copland, J. A., Marlow, L. A., Miller, J. L., Yin, P., Gao, B., Minter-Dykhouse, K., Tang, X., McLaughlin, S. A., Moreno-Aspitia, A., Schweitzer, A., Lu, Y., Hubbard, J., Northfelt, D. W., Gray, R. J., Hunt, K. & 10 others, Conners, A. L., Suman, V. J., Kalari, K. R., Ingle, J. N., Lou, Z., Visscher, D. W., Weinshilboum, R., Boughey, J. C., Goetz, M. P. & Wang, L., Dec 6 2017, In : Breast cancer research : BCR. 19, 1, 1 p.

Research output: Contribution to journalArticle

17 Scopus citations

Factors Influencing Use of Hormone Therapy for Ductal Carcinoma In Situ: A National Cancer Database Study

Nguyen, T. T., Hoskin, T. L., Day, C. N., Habermann, E. B., Goetz, M. P. & Boughey, J. C., Aug 1 2017, (Accepted/In press) In : Annals of Surgical Oncology. p. 1-10 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

First-in-human phase I Study of the tamoxifen metabolite Z-endoxifen in women with endocrine-refractory metastatic breast cancer

Goetz, M. P., Suman, V. J., Reid, J. M., Northfelt, D. W., Mahr, M. A., Ralya, A. T., Kuffel, M., Visscher, S. A., Kipp, B. R., Liu, M. C., Hawse, J. R., Ames, M. M., Ingle Buhrow, J. N., Safgren, S. L., McGovern, R. M., Black, J., Dockter, T., Haddad, T. C., Erlichman, C., Adjei, A. & 7 others, Collins, D., Streicher, H., Chalmers, Z. R., Frampton, G., Hawse, J. R., Doroshow, J. H. & Collins, J. M., Oct 20 2017, In : Journal of Clinical Oncology. 35, 30, p. 3391-3400 10 p.

Research output: Contribution to journalArticle

29 Scopus citations
13 Scopus citations

Impact of histopathology, tumor-infiltrating lymphocytes, and adjuvant chemotherapy on prognosis of triple-negative breast cancer

Leon-Ferre, R. A., Polley, M-Y., Liu, H., Gilbert, J. A., Cafourek, V., Hillman, D. W., Elkhanany, A., Akinhanmi, M., Lilyquist, J., Thomas, A., Negron, V., Boughey, J. C., Liu, M. C., Ingle, J. N., Kalari, K. R., Couch, F. J., Visscher, D. W. & Goetz, M. P., Sep 14 2017, (Accepted/In press) In : Breast Cancer Research and Treatment. p. 1-11 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Low PTEN levels and PIK3CA mutations predict resistance to neoadjuvant lapatinib and trastuzumab without chemotherapy in patients with HER2 over-expressing breast cancer

Rimawi, M. F., de Angelis, C., Contreras, A., Pareja, F., Geyer, F. C., Burke, K. A., Herrera, S., Wang, T., Mayer, I. A., Forero, A., Nanda, R., Goetz, M. P., Chang, J. C., Krop, I. E., Wolff, A. C., Pavlick, A. C., Fuqua, S. A. W., Gutierrez, C., Hilsenbeck, S. G., Li, M. M. & 4 others, Weigelt, B., Reis-Filho, J. S., Kent Osborne, C. & Schiff, R., Nov 7 2017, (Accepted/In press) In : Breast Cancer Research and Treatment. p. 1-10 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Molecular targeting of the Aurora-A/SMAD5 oncogenic axis restores chemosensitivity in human breast cancer cells

Opyrchal, M., Malgorzata, G., Salisbury, J. L., Goetz, M. P., Suman, V., Degnim, A., McCubrey, J., Haddad, T., Iankov, I., Kurokawa, C. B., Shumacher, N., Ingle, J. N., Galanis, E. & D'Assoro, A. B., 2017, In : Oncotarget. 8, 53, p. 91803-91816 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

MONARCH 3: Abemaciclib as initial therapy for advanced breast cancer

Goetz, M. P., Toi, M., Campone, M., Trédan, O., Bourayou, N., Sohn, J., Park, I. H., Paluch-Shimon, S., Huober, J., Chen, S. C., Manso, L., Barriga, S., Freedman, O. C., Jaliffe, G. G., Forrester, T., Frenzel, M., Smith, I. C. & Di Leo, A., Nov 10 2017, In : Journal of Clinical Oncology. 35, 32, p. 3638-3646 9 p.

Research output: Contribution to journalArticle

327 Scopus citations

NCCN Guidelines® insights breast cancer, version 1.2017: Featured updates to the NCCN Guidelines

Gradishar, W. J., Anderson, B. O., Balassanian, R., Blair, S. L., Burstein, H. J., Cyr, A., Elias, A. D., Farrar, W. B., Forero, A., Giordano, S. H., Goetz, M. P., Goldstein, L. J., Isakoff, S. J., Lyons, J., Kelly Marcom, P., Mayer, I. A., McCormick, B., Moran, M. S., O'Regan, R. M., Patel, S. A. & 13 others, Pierce, L. J., Reed, E. C., Salerno, K. E., Schwartzberg, L. S., Sitapati, A., Smith, K. L., Smith, M. L., Soliman, H., Somlo, G., Telli, M., Ward, J. H., Shead, D. A. & Kumar, R., Apr 1 2017, In : JNCCN Journal of the National Comprehensive Cancer Network. 15, 4, p. 433-451 19 p.

Research output: Contribution to journalArticle

Open Access
173 Scopus citations

NeoPalAna: Neoadjuvant palbociclib, a cyclin-dependent kinase 4/6 inhibitor, and anastrozole for clinical stage 2 or 3 estrogen receptor–positive breast cancer

Ma, C. X., Gao, F., Luo, J., Northfelt, D. W., Goetz, M. P., Forero, A., Hoog, J., Naughton, M., Ademuyiwa, F., Suresh, R., Anderson, K. S., Margenthaler, J., Aft, R., Hobday, T. J., Moynihan, T., Gillanders, W., Cyr, A., Eberlein, T. J., Hieken, T. J., Krontiras, H. & 14 others, Guo, Z., Lee, M. V., Spies, N. C., Skidmore, Z. L., Griffith, O. L., Griffith, M., Thomas, S., Bumb, C., Vij, K., Huang Bartlett, C., Koehler, M., Al-Kateb, H., Sanati, S. & Ellis, M. J., Aug 1 2017, In : Clinical Cancer Research. 23, 15, p. 4055-4065 11 p.

Research output: Contribution to journalArticle

96 Scopus citations

Neratinib efficacy and circulating tumor DNA detection of HER2 mutations in HER2 nonamplified metastatic breast cancer

Ma, C. X., Bose, R., Gao, F., Freedman, R. A., Telli, M. L., Kimmick, G., Winer, E., Naughton, M., Goetz, M. P., Russell, C., Tripathy, D., Cobleigh, M., Forero, A., Pluard, T. J., Anders, C., Niravath, P. A., Thomas, S., Anderson, J., Bumb, C., Banks, K. C. & 10 others, Lanman, R. B., Bryce, R., Lalani, A. S., Pfeifer, J., Hayes, D. F., Pegram, M., Blackwell, K., Bedard, P. L., Al-Kateb, H. & Ellis, M. J. C., Oct 1 2017, In : Clinical Cancer Research. 23, 19, p. 5687-5695 9 p.

Research output: Contribution to journalArticle

54 Scopus citations

North Central Cancer Treatment Group N0543 (Alliance): A phase 2 trial of pharmacogenetic-based dosing of irinotecan, oxaliplatin, and capecitabine as first-line therapy for patients with advanced small bowel adenocarcinoma

Mc Williams, R. R., Foster, N. R., Mahoney, M. R., Smyrk, T. C., Murray, J. A., Ames, M. M., Horvath, L. E., Schneider, D. J., Hobday, T. J., Jatoi, A., Meyers, J. P. & Goetz, M. P., 2017, (Accepted/In press) In : Cancer.

Research output: Contribution to journalArticle

15 Scopus citations
19 Scopus citations

Serum thymidine kinase 1 activity as a pharmacodynamic marker of cyclin-dependent kinase 4/6 inhibition in patients with early-stage breast cancer receiving neoadjuvant palbociclib

Bagegni, N., Thomas, S., Liu, N., Luo, J., Hoog, J., Northfelt, D. W., Goetz, M. P., Forero, A., Bergqvist, M., Karen, J., Neumüller, M., Suh, E. M., Guo, Z., Vij, K., Sanati, S., Ellis, M. & Ma, C. X., Nov 21 2017, In : Breast Cancer Research. 19, 1, 123.

Research output: Contribution to journalArticle

18 Scopus citations

Skeletal and uterotrophic effects of endoxifen in female rats

Gingery, A., Iwaniec, U. T., Subramaniam, M., Turner, R. T., Pitel, K. S., McGovern, R. M., Reid, J. M., Marler, R. J., Ingle, J. N., Goetz, M. P. & Hawse, J. R., Oct 1 2017, In : Endocrinology. 158, 10, p. 3354-3368 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway

Dudenkov, T. M., Ingle, J. N., Buzdar, A. U., Robson, M. E., Kubo, M., Ibrahim-zada, I., Batzler, A., Jenkins, G. D., Pietrzak, T. L., Carlson, E. E., Barman, P., Goetz, M. P., Northfelt, D. W., Moreno-Aspita, A., Williard, C. V., Kalari, K. R., Nakamura, Y., Wang, L. M. & Weinshilboum, R. M., Jul 1 2017, In : Breast Cancer Research and Treatment. 164, 1, p. 189-199 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Tumor and serum DNA methylation in women receiving preoperative chemotherapy with or without vorinostat in TBCRC008

Connolly, R. M., Fackler, M. J., Zhang, Z., Zhou, X. C., Goetz, M. P., Boughey, J. C., Walsh, B., Carpenter, J. T., Storniolo, A. M., Watkins, S. P., Gabrielson, E. W., Stearns, V. & Sukumar, S., Sep 16 2017, (Accepted/In press) In : Breast Cancer Research and Treatment. p. 1-10 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Tumor Sequencing and Patient-Derived Xenografts in the Neoadjuvant Treatment of Breast Cancer

Goetz, M. P., Kalari, K. R., Suman, V. J., Moyer, A. M., Yu, J., Visscher, D. W., Dockter, T. J., Vedell, P. T., Sinnwell, J. P., Tang, X., Thompson, K. J., McLaughlin, S. A., Moreno-Aspitia, A., Copland, J. A., Northfelt, D. W., Gray, R. J., Hunt, K., Conners, A., Weinshilboum, R., Wang, L. & 36 others, Boughey, J. C., Goetz, M. P., Kalari, K. R., Suman, V. J., Moyer, A. M., Yu, J., Visscher, D. W., Dockter, T. J., Vedell, P. T., Sinnwell, J. P., Tang, X., Thompson, K. J., Barman, P., Mahoney, D. W., Carlson, E., Hart, S. N., Yin, P., Qin, B., Felten, S. J., McLaughlin, S. A., Moreno-Aspitia, A., Copland, J. A., Northfelt, D. W., Gray, R. J., Hunt, K., Conners, A., Sicotte, H., Eckel-Passow, J. E., Kocher, J. P., Ingle, J. N., Ellingson, M. S., McDonough, M., Wieben, E. D., Weinshilboum, R., Wang, L. & Boughey, J. C., Jul 1 2017, In : Journal of the National Cancer Institute. 109, 7

Research output: Contribution to journalArticle

23 Scopus citations