Matthew Philip Goetz, MD

  • 9485 Citations
  • 46 Scopus h-Index
20022020

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A combinatorial biomarker predicts pathologic complete response to neoadjuvant lapatinib and trastuzumab without chemotherapy in patients with HER2+ breast cancer

Veeraraghavan, J., De Angelis, C., Mao, R., Wang, T., Herrera, S., Pavlick, A. C., Contreras, A., Nuciforo, P., Mayer, I. A., Forero, A., Nanda, R., Goetz, M. P., Chang, J. C., Wolff, A. C., Krop, I. E., Fuqua, S. A. W., Prat, A., Hilsenbeck, S. G., Weigelt, B., Reis-Filho, J. S. & 4 others, Gutierrez, C., Osborne, C. K., Rimawi, M. F. & Schiff, R., Jun 1 2019, In : Annals of Oncology. 30, 6, p. 927-933 7 p., mdz076.

Research output: Contribution to journalArticle

14 Scopus citations

A comprehensive analysis of breast cancer microbiota and host gene expression

Thompson, K. J., Ingle, J. N., Tang, X., Chia, N., Jeraldo, P. R., Walther-Antonio, M. R., Kandimalla, K. K., Johnson, S., Yao, J. Z., Harrington, S. C., Suman, V. J., Wang, L., Weinshilboum, R. L., Boughey, J. C., Kocher, J. P., Nelson, H., Goetz, M. P. & Kalari, K. R., Nov 2017, In : PloS one. 12, 11, e0188873.

Research output: Contribution to journalArticle

23 Scopus citations

Activation of PI3K/Akt/mTOR signaling in the tumor stroma drives endocrine therapy-dependent breast tumor regression

Polo, M. L., Riggio, M., May, M., Rodríguez, M. J., Perrone, M. C., Stallings-Mann, M., Kaen, D., Frost, M., Goetz, M., Boughey, J., Lanari, C., Radisky, D. & Novaro, V., 2015, In : Oncotarget. 6, 26, p. 22081-22097 17 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Adjuvant chemotherapy guided by a 21-gene expression assay in breast cancer

Sparano, J. A., Gray, R. J., Makower, D. F., Pritchard, K. I., Albain, K. S., Hayes, D. F., Geyer, C. E., Dees, E. C., Goetz, M. P., Olson, J. A., Lively, T., Badve, S. S., Saphner, T. J., Wagner, L. I., Whelan, T. J., Ellis, M. J., Paik, S., Wood, W. C., Ravdin, P. M., Keane, M. M. & 10 others, Gomez Moreno, H. L., Reddy, P. S., Goggins, T. F., Mayer, I. A., Brufsky, A. M., Toppmeyer, D. L., Kaklamani, V. G., Berenberg, J. L., Abrams, J. & Sledge, G. W., Jul 12 2018, In : New England Journal of Medicine. 379, 2, p. 111-121 11 p.

Research output: Contribution to journalArticle

498 Scopus citations

A first-in-human phase i study of the oral p38 MAPK inhibitor, ralimetinib (LY2228820 Dimesylate), in patients with advanced cancer

Patnaik, A., Haluska, P., Tolcher, A. W., Erlichman, C., Papadopoulos, K. P., Lensing, J. L., Beeram, M., Molina, J. R., Rasco, D. W., Arcos, R. R., Kelly, C. S., Wijayawardana, S. R., Zhang, X., Stancato, L. F., Bell, R., Shi, P., Kulanthaivel, P., Pitou, C., Mulle, L. B., Farrington, D. L. & 2 others, Chan, E. M. & Goetz, M. P., Mar 1 2016, In : Clinical Cancer Research. 22, 5, p. 1095-1102 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

A multidisciplinary approach to the management of breast cancer, part 1: Prevention and diagnosis

Pruthi, S., Brandt, K. R., Degnim, A. C., Goetz, M. P., Perez, E. A., Reynolds, C. A., Schomberg, P. J., Dy, G. K. & Ingle, J. N., Aug 2007, In : Mayo Clinic proceedings. 82, 8, p. 999-1012 14 p.

Research output: Contribution to journalArticle

40 Scopus citations

A multidisciplinary approach to the management of breast cancer, part 2: Therapeutic considerations

Pruthi, S., Boughey, J. C., Brandt, K. R., Degnim, A. C., Dy, G. K., Goetz, M. P., Perez, E. A., Reynolds, C. A., Schomberg, P. J. & Ingle, J. N., Sep 2007, In : Mayo Clinic proceedings. 82, 9, p. 1131-1140 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2

Dudenkov, T. M., Liu, D., Cairns, J., Devarajan, S., Zhuang, Y., Ingle, J. N., Buzdar, A. U., Robson, M. E., Kubo, M., Batzler, A., Barman, P., Jenkins, G. D., Carlson, E. E., Goetz, M. P., Northfelt, D. W., Moreno-Aspitia, A., Desta, Z., Reid, J. M., Kalari, K. R., Wang, L. & 1 others, Weinshilboum, R. M., Jul 2019, In : Clinical pharmacology and therapeutics. 106, 1, p. 219-227 9 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Anastrozole has an association between degree of estrogen suppression and outcomes in early breast cancer and is a ligand for estrogen receptor

Ingle, J. N., Cairns, J., Suman, V. J., Shepherd, L. E., Fasching, P. A., Hoskin, T. L., Singh, R. J., Desta, Z., Kalari, K. R., Ellis, M. J., Goss, P. E., Chen, B. E., Volz, B., Barman, P., Carlson, E. E., Haddad, T., Goetz, M. P., Goodnature, B., Cuellar, M. E., Walters, M. A. & 4 others, Correia, C., Kaufmann, S. H., Weinshilboum, R. M. & Wang, L., Jun 15 2020, In : Clinical Cancer Research. 26, 12, p. 2986-2996 11 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Androgen receptor-positive triple negative breast cancer: A unique breast cancer subtype

McGhan, L. J., McCullough, A. E., Protheroe, C. A., Dueck, A. C., Lee, J. J., Nunez-Nateras, R., Castle, E. P., Gray, R. J., Wasif, N., Goetz, M. P., Hawse, J. R., Henry, T. J., Barrett, M. T., Cunliffe, H. E. & Pockaj, B. A., Feb 1 2014, In : Annals of surgical oncology. 21, 2, p. 361-367 7 p.

Research output: Contribution to journalArticle

80 Scopus citations

Antitumor activity of Z-endoxifen in aromatase inhibitor-sensitive and aromatase inhibitor-resistant estrogen receptor-positive breast cancer

Jayaraman, S., Hou, X., Kuffel, M. J., Suman, V. J., Hoskin, T. L., Reinicke, K. E., Monroe, D. G., Kalari, K. R., Tang, X., Zeldenrust, M. A., Cheng, J., Bruinsma, E. S., Buhrow, S. A., McGovern, R. M., Safgren, S. L., Walden, C. A., Carter, J. M., Reid, J. M., Ingle, J. N., Ames, M. M. & 2 others, Hawse, J. R. & Goetz, M. P., May 19 2020, In : Breast Cancer Research. 22, 1, 51.

Research output: Contribution to journalArticle

Open Access

A phase II trial of neoadjuvant MK-2206, an AKT inhibitor, with anastrozole in clinical stage II or III PIK3CA-mutant ER-positive and HER2-negative breast cancer

Ma, C. X., Suman, V., Goetz, M. P., Northfelt, D., Burkard, M. E., Ademuyiwa, F., Naughton, M., Margenthaler, J., Aft, R., Gray, R., Tevaarwerk, A., Wilke, L., Haddad, T., Moynihan, T., Loprinzi, C., Hieken, T., Barnell, E. K., Skidmore, Z. L., Feng, Y. Y., Krysiak, K. & 14 others, Hoog, J., Guo, Z., Nehring, L., Wisinski, K. B., Mardis, E., Hagemann, I. S., Vij, K., Sanati, S., Al-Kateb, H., Griffith, O. L., Griffith, M., Doyle, L., Erlichman, C. & Ellis, M. J., Nov 15 2017, In : Clinical Cancer Research. 23, 22, p. 6823-6832 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

A phase I study of cilengitide and paclitaxel in patients with advanced solid tumors

Haddad, T., Qin, R., Lupu, R., Satele, D., Eadens, M., Goetz, M. P., Erlichman, C. & Molina, J., Jun 1 2017, In : Cancer Chemotherapy and Pharmacology. 79, 6, p. 1221-1227 7 p.

Research output: Contribution to journalArticle

18 Scopus citations
1 Scopus citations

A phase i trial of the IGF-1R antibody Cixutumumab in combination with temsirolimus in patients with metastatic breast cancer

Ma, C. X., Suman, V. J., Goetz, M., Haluska, P., Moynihan, T., Nanda, R., Olopade, O., Pluard, T., Guo, Z., Chen, H. X., Erlichman, C., Ellis, M. J. & Fleming, G. F., May 2013, In : Breast Cancer Research and Treatment. 139, 1, p. 145-153 9 p.

Research output: Contribution to journalArticle

48 Scopus citations

A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2

Vachon, C. M., Schaid, D. J., Ingle, J. N., Wickerham, D. L., Kubo, M., Mushiroda, T., Goetz, M. P., Carlson, E. E., Paik, S., Wolmark, N., Nakamura, Y., Wang, L., Weinshilboum, R. & Couch, F. J., 2015, In : Breast Cancer Research and Treatment. 149, 2, p. 517-523 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen

Schroth, W., Goetz, M. P., Hamann, U., Fasching, P. A., Schmidt, M., Winter, S., Fritz, P., Simon, W., Suman, V. J., Ames, M. M., Safgren, S. L., Kuffel, M. J., Ulmer, H. U., Boländer, J., Strick, R., Beckmann, M. W., Koelbl, H., Weinshilboum, R. M., Ingle, J. N., Eichelbaum, M. & 2 others, Schwab, M. & Brauch, H., 2009, In : JAMA - Journal of the American Medical Association. 302, 13, p. 1429-1436 8 p.

Research output: Contribution to journalArticle

427 Scopus citations

A transcriptionally definable subgroup of triple-negative breast and ovarian cancer samples shows sensitivity to Hsp90 inhibition

Shee, K., Wells, J. D., Ung, M., Hampsch, R. A., Traphagen, N. A., Yang, W., Liu, S. C., Zeldenrust, M. A., Wang, L., Kalari, K. R., Yu, J., Boughey, J. C., Demidenko, E., Kettenbach, A. N., Cheng, C., Goetz, M. P. & Miller, T. W., Jan 1 2020, In : Clinical Cancer Research. 26, 1, p. 159-170 12 p.

Research output: Contribution to journalArticle

ATR inhibition is a promising radiosensitizing strategy for triple-negative breast cancer

Tu, X., Kahila, M. M., Zhou, Q., Yu, J., Kalari, K. R., Wang, L., Harmsen, W. S., Yuan, J., Boughey, J. C., Goetz, M. P., Sarkaria, J. N., Lou, Z. & Mutter, R. W., Nov 2018, In : Molecular cancer therapeutics. 17, 11, p. 2462-2472 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

A two-gene expression ratio of homeobox 13 and interleukin-17B receptor for prediction of recurrence and survival in women receiving adjuvant tamoxifen

Goetz, M. P., Suman, V. J., Ingle, J. N., Nibbe, A. M., Visscher, D. W., Reynolds, C. A., Lingle, W. L., Erlander, M., Ma, X. J., Sgroi, D. C., Perez, E. A. & Couch, F. J., Apr 1 2006, In : Clinical Cancer Research. 12, 7 I, p. 2080-2087 8 p.

Research output: Contribution to journalArticle

141 Scopus citations

Aurora-A mitotic kinase induces endocrine resistance through down-regulation of ERα expression in initially ERα+ breast cancer cells

Opyrchal, M., Salisbury, J. L., Zhang, S., McCubrey, J., Hawse, J., Goetz, M. P., Lomberk, G. A., Haddad, T., Degnim, A., Lange, C., Ingle, J. N., Galanis, E. & D'Assoro, A. B., May 9 2014, In : PloS one. 9, 5, e96995.

Research output: Contribution to journalArticle

15 Scopus citations

Automated discovery of drug treatment patterns for endocrine therapy of breast cancer within an electronic medical record

Savova, G. K., Olson, J. E., Murphy, S. P., Cafourek, V. L., Couch, F. J., Goetz, M. P., Ingle, J. N., Suman, V. J., Chute, C. G. & Weinshilboum, R. M., Jun 2012, In : Journal of the American Medical Informatics Association. 19, E1, p. e83-e89

Research output: Contribution to journalArticle

19 Scopus citations

Baseline estrogen levels in postmenopausal women participating in the MAP.3 breast cancer chemoprevention trial

MAP.3 Investigators, Jun 1 2020, In : Menopause (New York, N.Y.). 27, 6, p. 693-700 8 p.

Research output: Contribution to journalArticle

Breast cancer, version 1.2016 featured updates to the NCCN guidelines

Gradishar, W. J., Anderson, B. O., Balassanian, R., Blair, S. L., Burstein, H. J., Cyr, A., Elias, A. D., Farrar, W. B., Forero, A., Giordano, S. H., Goetz, M., Goldstein, L. J., Hudis, C. A., Isakoff, S. J., Marcom, P. K., Mayer, I. A., McCormick, B., Moran, M., Patel, S. A., Pierce, L. J. & 11 others, Reed, E. C., Salerno, K. E., Schwartzberg, L. S., Smith, K. L., Smith, M. L., Soliman, H., Somlo, G., Telli, M., Ward, J. H., Shead, D. A. & Kumar, R., Dec 1 2015, In : JNCCN Journal of the National Comprehensive Cancer Network. 13, 12, p. 1475-1485 11 p.

Research output: Contribution to journalArticle

Open Access
104 Scopus citations

Breast cancer, version 3.2018 featured updates to the NCCN guidelines

Goetz, M. P., Gradishar, W. J., Anderson, B. O., Abraham, J., Aft, R., Allison, K. H., Blair, S. L., Burstein, H. J., Dang, C., Elias, A. D., Farrar, W. B., Giordano, S. H., Goldstein, L. J., Isakoff, S. J., Lyons, J., Kelly Marcom, P., Mayer, I. A., Moran, M. S., Mortimer, J., O’Regan, R. M. & 13 others, Patel, S. A., Pierce, L. J., Reed, E. C., Rugo, H. S., Sitapati, A., Smith, K. L., Smith, M. L., Soliman, H., Telli, M. L., Ward, J. H., Young, J. S., Shead, D. A. & Kumar, R., Feb 2019, In : JNCCN Journal of the National Comprehensive Cancer Network. 17, 2, p. 118-126 9 p.

Research output: Contribution to journalArticle

Open Access
56 Scopus citations

Breast cancer, version 3.2020

Gradishar, W. J., Anderson, B. O., Abraham, J., Aft, R., Agnese, D., Allison, K. H., Blair, S. L., Burstein, H. J., Dang, C., Elias, A. D., Giordano, S. H., Goetz, M. P., Goldstein, L. J., Isakoff, S. J., Krishnamurthy, J., Lyons, J., Marcom, P. K., Matro, J., Mayer, I. A., Moran, M. S. & 15 others, Mortimer, J., O’Regan, R. M., Patel, S. A., Pierce, L. J., Rugo, H. S., Sitapati, A., Smith, K. L., Smith, M. L., Soliman, H., Stringer-Reasor, E. M., Telli, M. L., Ward, J. H., Young, J. S., Burns, J. L. & Kumar, R., Apr 2020, In : JNCCN Journal of the National Comprehensive Cancer Network. 18, 4, p. 452-478 27 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

Breast medical oncologists' use of standard prognostic factors to predict a 21-gene recurrence score

Kamal, A. H., Loprinzi, C. L., Reynolds, C., Dueck, A. C., Geiger, X. J., Ingle, J. N., Carlson, R. W., Hobday, T. J., Winer, E. P. & Goetz, M. P., 2011, In : Oncologist. 16, 10, p. 1359-1366 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Carnitine Palmitoyltransferase 1A Has a Lysine Succinyltransferase Activity

Kurmi, K., Hitosugi, S., Wiese, E. K., Boakye-Agyeman, F., Gonsalves, W. I., Lou, Z., Karnitz, L. M., Goetz, M. P. & Hitosugi, T., Feb 6 2018, In : Cell reports. 22, 6, p. 1365-1373 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1

Liu, T., Yu, J., Deng, M., Yin, Y., Zhang, H., Luo, K., Qin, B., Li, Y., Wu, C., Ren, T., Han, Y., Yin, P., Kim, J. J., Lee, S. B., Lin, J., Zhang, L., Zhang, J., Nowsheen, S., Wang, L., Boughey, J. & 3 others, Goetz, M. P., Yuan, J. & Lou, Z., Jan 9 2017, In : Nature communications. 8, 13923.

Research output: Contribution to journalArticle

56 Scopus citations

Clinical and genomic risk to guide the use of adjuvant therapy for breast cancer

Sparano, J. A., Gray, R. J., Ravdin, P. M., Makower, D. F., Pritchard, K. I., Albain, K. S., Hayes, D. F., Geyer, C. E., Dees, E. C., Goetz, M. P., Olson, J. A., Lively, T., Badve, S. S., Saphner, T. J., Wagner, L. I., Whelan, T. J., Ellis, M. J., Paik, S., Wood, W. C., Keane, M. M. & 10 others, Gomez Moreno, H. L., Reddy, P. S., Goggins, T. F., Mayer, I. A., Brufsky, A. M., Toppmeyer, D. L., Kaklamani, V. G., Berenberg, J. L., Abrams, J. & Sledge, G. W., Jun 20 2019, In : New England Journal of Medicine. 380, 25, p. 2395-2405 11 p.

Research output: Contribution to journalArticle

77 Scopus citations

Clinical Outcomes in Early Breast Cancer with a High 21-Gene Recurrence Score of 26 to 100 Assigned to Adjuvant Chemotherapy Plus Endocrine Therapy: A Secondary Analysis of the TAILORx Randomized Clinical Trial

Sparano, J. A., Gray, R. J., Makower, D. F., Albain, K. S., Saphner, T. J., Badve, S. S., Wagner, L. I., Kaklamani, V. G., Keane, M. M., Gomez, H. L., Reddy, P. S., Goggins, T. F., Mayer, I. A., Toppmeyer, D. L., Brufsky, A. M., Goetz, M. P., Berenberg, J. L., Mahalcioiu, C., Desbiens, C., Hayes, D. F. & 9 others, Dees, E. C., Geyer, C. E., Olson, J. A., Wood, W. C., Lively, T., Paik, S., Ellis, M. J., Abrams, J. & Sledge, G. W., Mar 2020, In : JAMA Oncology. 6, 3, p. 367-374 8 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy

Goetz, M. P., Sangkuhl, K., Guchelaar, H. J., Schwab, M., Province, M., Whirl-Carrillo, M., Symmans, W. F., McLeod, H. L., Ratain, M. J., Zembutsu, H., Gaedigk, A., van Schaik, R. H., Ingle, J. N., Caudle, K. E. & Klein, T. E., May 2018, In : Clinical pharmacology and therapeutics. 103, 5, p. 770-777 8 p.

Research output: Contribution to journalArticle

80 Scopus citations

Clinical practice guidelines in oncology

Gradishar, W. J., Anderson, B. O., Balassanian, R., Blair, S. L., Burstein, H. J., Cyr, A., Elias, A. D., Farrar, W. B., Forero, A., Giordano, S. H., Goetz, M. P., Goldstein, L. J., Isakoff, S. J., Lyons, J., Kelly Marcom, P., Mayer, I. A., McCormick, B., Moran, M. S., O’Regan, R. M., Patel, S. A. & 13 others, Pierce, L. J., Reed, E. C., Salerno, K. E., Schwartzberg, L. S., Sitapati, A., Smith, K. L., Smith, M. L., Soliman, H., Somlo, G., Telli, M. L., Ward, J. H., Kumar, R. & Shead, D. A., Mar 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 3, p. 310-320 11 p.

Research output: Contribution to journalArticle

124 Scopus citations

Clinical trial designs for prospective validation of biomarkers

Mandrekar, S. J., Grothey, A., Goetz, M. P. & Sargent, D. J., Oct 17 2005, In : American Journal of PharmacoGenomics. 5, 5, p. 317-325 9 p.

Research output: Contribution to journalArticle

40 Scopus citations

Clonal expansion of antitumor T cells in breast cancer correlates with response to neoadjuvant chemotherapy

Park, J. H., Jang, M., Tarhan, Y. E., Katagiri, T., Sasa, M., Miyoshi, Y., Kalari, K. R., Suman, V. J., Weinshilboum, R., Wang, L., Boughey, J. C., Goetz, M. P. & Nakamura, Y., Aug 2016, In : International journal of oncology. 49, 2, p. 471-478 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Colonic polyposis and neoplasia in Cowden syndrome

Stanich, P. P., Owens, V. L., Sweetser, S., Khambatta, S., Smyrk, T. C., Richardson, R. L., Goetz, M. P. & Patnaik, M. M., Jun 2011, In : Mayo Clinic proceedings. 86, 6, p. 489-492 4 p.

Research output: Contribution to journalArticle

46 Scopus citations

Comparative Uterotrophic Effects of Endoxifen and Tamoxifen in Ovariectomized Sprague-Dawley Rats

Schweikart, K. M., Eldridge, S. R., Safgren, S. L., Parman, T., Reid, J. M., Ames, M. M., Goetz, M. P. & Davis, M. A., Dec 2014, In : Toxicologic Pathology. 42, 8, p. 1188-1196 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Comparison of 99mTc-sestamibi molecular breast imaging and breast MRI in patients with invasive breast cancer receiving neoadjuvant chemotherapy

Hunt, K. N., Conners, A. L., Goetz, M. P., O’Connor, M. K., Suman, V., Kalari, K., Weinshilboum, R., Wang, L., Carter, J., McLaughlin, S. A., Aspitia, A. M., Gray, R. J., Northfelt, D. & Boughey, J. C., Jan 1 2019, In : American Journal of Roentgenology. 213, 4, p. 932-943 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Concordance between predicted HLA type using next generation sequencing data generated for non-HLA purposes and clinical HLA type

Moyer, A. M., Dukek, B., Duellman, P., Schneider, B., Wakefield, L., Skierka, J. M., Avula, R., Bhagwate, A. V., Kalari, K. R., Kreuter, J. D., Goetz, M. P., Boughey, J. C., Black, J. L. & Gandhi, M. J., Aug 2020, In : Human Immunology. 81, 8, p. 423-429 7 p.

Research output: Contribution to journalArticle

CYP2D6 Genotype and Adjuvant Tamoxifen: Meta-Analysis of Heterogeneous Study Populations

Province, M. A., Goetz, M. P., Brauch, H., Flockhart, D. A., Hebert, J. M., Whaley, R., Suman, V. J., Schroth, W., Winter, S., Zembutsu, H., Mushiroda, T., Newman, W. G., Lee, M. T. M., Ambrosone, C. B., Beckmann, M. W., Choi, J. Y., Dieudonné, A. S., Fasching, P. A., Ferraldeschi, R., Gong, L. & 44 others, Haschke-Becher, E., Howell, A., Jordan, L. B., Hamann, U., Kiyotani, K., Krippl, P., Lambrechts, D., Latif, A., Langsenlehner, U., Lorizio, W., Neven, P., Nguyen, A. T., Park, B. W., Purdie, C. A., Quinlan, P., Renner, W., Schmidt, M., Schwab, M., Shin, J. G., Stingl, J. C., Wegman, P., Wingren, S., Wu, A. H. B., Ziv, E., Zirpoli, G., Thompson, A. M., Jordan, V. C., Nakamura, Y., Altman, R. B., Ames, M. M., Weinshilboum, R. M., Eichelbaum, M., Ingle, J. N., Klein, T. E., Boländer, J., Ulmer, H. U., Fischer-Bosch, M., Fritz, P., Simon, W., Bryan, Y., Strick, R., Koelbl, H., Ambrosone, C. A. & H, E. Z., Feb 1 2014, In : Clinical pharmacology and therapeutics. 95, 2, p. 216-227 12 p.

Research output: Contribution to journalArticle

119 Scopus citations

CYP2D6 metabolism and patient outcome in the Austrian breast and colorectal cancer study group trial (ABCSG) 8

Goetz, M. P., Suman, V. J., Hoskin, T. L., Gnant, M., Filipits, M., Safgren, S. L., Kuffel, M., Jakesz, R., Rudas, M., Greil, R., Dietze, O., Lang, A., Offner, F., Reynolds, C. A., Weinshilboum, R. M., Ames, M. M. & Ingle, J. N., Jan 15 2013, In : Clinical Cancer Research. 19, 2, p. 500-507 8 p.

Research output: Contribution to journalArticle

82 Scopus citations

Cytochrome P450 2D6 and homeobox 13/interleukin-17B receptor: Combining inherited and tumor gene markers for prediction of tamoxifen resistance

Goetz, M. P., Suman, V. J., Couch, F. J., Ames, M. M., Rae, J. M., Erlander, M. G., Ma, X. J., Sgroi, D. C., Reynolds, C. A., Lingle, W. L., Weinshilboum, R. M., Flockhart, D. A., Desta, Z., Perez, E. A. & Ingle, J. N., Sep 15 2008, In : Clinical Cancer Research. 14, 18, p. 5864-5868 5 p.

Research output: Contribution to journalArticle

21 Scopus citations

Deep sequencing across germline genome-wide association study signals relating to breast cancer events in women receiving aromatase inhibitors for adjuvant therapy of early breast cancer

Ingle, J. N., Kalari, K. R., Momozawa, Y., Kubo, M., Furukawa, Y., Shepherd, L. E., Ellis, M. J., Goss, P. E., Barman, P., Carlson, E. E., Sinnwell, J. P., Tang, X., Goetz, M. P., Chen, B. E., Cairns, J., Weinshilboum, R. M. & Wang, L., Oct 1 2019, In : Pharmacogenetics and genomics. 29, 8, p. 183-191 9 p.

Research output: Contribution to journalArticle

Development, characterization, and applications of a novel estrogen receptor beta monoclonal antibody

Wu, X., Subramaniam, M., Negron, V., Cicek, M., Reynolds, C., Lingle, W. L., Goetz, M. P., Ingle, J. N., Spelsberg, T. C. & Hawse, J. R., Feb 2012, In : Journal of cellular biochemistry. 113, 2, p. 711-723 13 p.

Research output: Contribution to journalArticle

35 Scopus citations

Discovery of a glucocorticoid receptor (gr) activity signature using selective gr antagonis in er-negative breast cancer

West, D. C., Kocherginsky, M., Tonsing-Carter, E. Y., Dolcen, D. N., Hosfield, D. J., Lastra, R. R., Sinnwell, J. P., Thompson, K. J., Bowie, K. R., Harkless, R. V., Skor, M. N., Pierce, C. F., Styke, S. C., Kim, C. R., De Wet, L., Greene, G. L., Boughey, J. C., Goetz, M. P., Kalari, K. R., Wang, L. & 3 others, Fleming, G. F., Gyorffy, B. & Conzen, S. D., Jul 15 2018, In : Clinical Cancer Research. 24, 14, p. 3433-3446 14 p.

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11 Scopus citations

DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine

Yu, J., Qin, B., Moyer, A. M., Nowsheen, S., Liu, T., Qin, S., Zhuang, Y., Liu, D., Lu, S. W., Kalari, K. R., Visscher, D. W., Copland, J. A., McLaughlin, S. A., Moreno-Aspitia, A., Northfelt, D. W., Gray, R. J., Lou, Z., Suman, V. J., Weinshilboum, R., Boughey, J. C. & 2 others, Goetz, M. P. & Wang, L., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2376-2388 13 p.

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37 Scopus citations

Efficacy of the PARP inhibitor veliparib with carboplatin or as a single agent in patients with germline BRCA1- or BRCA2-associated metastatic breast cancer: California Cancer Consortium trial NCT01149083

Somlo, G., Frankel, P. H., Arun, B. K., Ma, C. X., Garcia, A. A., Cigler, T., Cream, L. V., Harvey, H. A., Sparano, J. A., Nanda, R., Chew, H. K., Moynihan, T. J., Vahdat, L. T., Goetz, M. P., Beumer, J. H., Hurria, A., Mortimer, J., Piekarz, R., Sand, S., Herzog, J. & 7 others, Van Tongeren, L. R., Ferry-Galow, K. V., Chen, A. P., Ruel, C., Newman, E. M., Gandara, D. R. & Weitzel, J. N., Aug 1 2017, In : Clinical Cancer Research. 23, 15, p. 4066-4076 11 p.

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44 Scopus citations

Endoxifen's Molecular Mechanisms of Action Are Concentration Dependent and Different than That of Other Anti-Estrogens

Hawse, J. R., Subramaniam, M., Cicek, M., Wu, X., Gingery, A., Grygo, S. B., Sun, Z., Pitel, K. S., Lingle, W. L., Goetz, M. P., Ingle, J. N. & Spelsberg, T. C., Jan 28 2013, In : PloS one. 8, 1, e54613.

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34 Scopus citations

ERβ1: Characterization, prognosis, and evaluation of treatment strategies in ERα-positive and -negative breast cancer

Reese, J. M., Suman, V. J., Subramaniam, M., Wu, X., Negron, V., Gingery, A., Pitel, K. S., Shah, S. S., Cunliffe, H. E., McCullough, A. E., Pockaj, B. A., Couch, F. J., Olson, J. E., Reynolds, C., Lingle, W. L., Spelsberg, T. C., Goetz, M. P., Ingle, J. N. & Hawse, J. R., Oct 7 2014, In : BMC cancer. 14, 1, 749.

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30 Scopus citations

ERβ inhibits cyclin dependent kinases 1 and 7 in triple negative breast cancer

Reese, J. M., Bruinsma, E. S., Monroe, D. G., Negron, V., Suman, V. J., Ingle, J. N., Goetz, M. P. & Hawse, J. R., 2017, In : Oncotarget. 8, 57, p. 96506-96521 16 p.

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15 Scopus citations