Matthew Philip Goetz, MD

  • 9276 Citations
  • 46 Scopus h-Index
20022020

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2020

Anastrozole has an association between degree of estrogen suppression and outcomes in early breast cancer and is a ligand for estrogen receptor

Ingle, J. N., Cairns, J., Suman, V. J., Shepherd, L. E., Fasching, P. A., Hoskin, T. L., Singh, R. J., Desta, Z., Kalari, K. R., Ellis, M. J., Goss, P. E., Chen, B. E., Volz, B., Barman, P., Carlson, E. E., Haddad, T., Goetz, M. P., Goodnature, B., Cuellar, M. E., Walters, M. A. & 4 others, Correia, C., Kaufmann, S. H., Weinshilboum, R. M. & Wang, L., Jun 15 2020, In : Clinical Cancer Research. 26, 12, p. 2986-2996 11 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Antitumor activity of Z-endoxifen in aromatase inhibitor-sensitive and aromatase inhibitor-resistant estrogen receptor-positive breast cancer

Jayaraman, S., Hou, X., Kuffel, M. J., Suman, V. J., Hoskin, T. L., Reinicke, K. E., Monroe, D. G., Kalari, K. R., Tang, X., Zeldenrust, M. A., Cheng, J., Bruinsma, E. S., Buhrow, S. A., McGovern, R. M., Safgren, S. L., Walden, C. A., Carter, J. M., Reid, J. M., Ingle, J. N., Ames, M. M. & 2 others, Hawse, J. R. & Goetz, M. P., May 19 2020, In : Breast Cancer Research. 22, 1, 51.

Research output: Contribution to journalArticle

Open Access

A transcriptionally definable subgroup of triple-negative breast and ovarian cancer samples shows sensitivity to Hsp90 inhibition

Shee, K., Wells, J. D., Ung, M., Hampsch, R. A., Traphagen, N. A., Yang, W., Liu, S. C., Zeldenrust, M. A., Wang, L., Kalari, K. R., Yu, J., Boughey, J. C., Demidenko, E., Kettenbach, A. N., Cheng, C., Goetz, M. P. & Miller, T. W., Jan 1 2020, In : Clinical Cancer Research. 26, 1, p. 159-170 12 p.

Research output: Contribution to journalArticle

Baseline estrogen levels in postmenopausal women participating in the MAP.3 breast cancer chemoprevention trial

MAP.3 Investigators, Jun 1 2020, In : Menopause (New York, N.Y.). 27, 6, p. 693-700 8 p.

Research output: Contribution to journalArticle

Breast cancer, version 3.2020

Gradishar, W. J., Anderson, B. O., Abraham, J., Aft, R., Agnese, D., Allison, K. H., Blair, S. L., Burstein, H. J., Dang, C., Elias, A. D., Giordano, S. H., Goetz, M. P., Goldstein, L. J., Isakoff, S. J., Krishnamurthy, J., Lyons, J., Marcom, P. K., Matro, J., Mayer, I. A., Moran, M. S. & 15 others, Mortimer, J., O’Regan, R. M., Patel, S. A., Pierce, L. J., Rugo, H. S., Sitapati, A., Smith, K. L., Smith, M. L., Soliman, H., Stringer-Reasor, E. M., Telli, M. L., Ward, J. H., Young, J. S., Burns, J. L. & Kumar, R., Apr 2020, In : JNCCN Journal of the National Comprehensive Cancer Network. 18, 4, p. 452-478 27 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Clinical Outcomes in Early Breast Cancer with a High 21-Gene Recurrence Score of 26 to 100 Assigned to Adjuvant Chemotherapy Plus Endocrine Therapy: A Secondary Analysis of the TAILORx Randomized Clinical Trial

Sparano, J. A., Gray, R. J., Makower, D. F., Albain, K. S., Saphner, T. J., Badve, S. S., Wagner, L. I., Kaklamani, V. G., Keane, M. M., Gomez, H. L., Reddy, P. S., Goggins, T. F., Mayer, I. A., Toppmeyer, D. L., Brufsky, A. M., Goetz, M. P., Berenberg, J. L., Mahalcioiu, C., Desbiens, C., Hayes, D. F. & 9 others, Dees, E. C., Geyer, C. E., Olson, J. A., Wood, W. C., Lively, T., Paik, S., Ellis, M. J., Abrams, J. & Sledge, G. W., Mar 2020, In : JAMA Oncology. 6, 3, p. 367-374 8 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Concordance between predicted HLA type using next generation sequencing data generated for non-HLA purposes and clinical HLA type

Moyer, A. M., Dukek, B., Duellman, P., Schneider, B., Wakefield, L., Skierka, J. M., Avula, R., Bhagwate, A. V., Kalari, K. R., Kreuter, J. D., Goetz, M. P., Boughey, J. C., Black, J. L. & Gandhi, M. J., Aug 2020, In : Human Immunology. 81, 8, p. 423-429 7 p.

Research output: Contribution to journalArticle

Evaluation of germline genetic testing criteria in a hospital-based series of women with breast cancer

Yadav, S., Hu, C., Hart, S. N., Boddicker, N., Polley, E. C., Na, J., Gnanaolivu, R., Lee, K. Y., Lindstrom, T., Armasu, S., Fitz-Gibbon, P., Ghosh, K., Stan, D. L., Pruthi, S., Neal, L., Sandhu, N., Rhodes, D. J., Klassen, C., Peethambaram, P. P., Haddad, T. C. & 7 others, Olson, J. E., Hoskin, T. L., Goetz, M. P., Domchek, S. M., Boughey, J. C., Ruddy, K. J. & Couch, F. J., May 1 2020, In : Journal of Clinical Oncology. 38, 13, p. 1409-1418 10 p.

Research output: Contribution to journalArticle

Open Access

Folate receptor alpha expression associates with improved disease-free survival in triple negative breast cancer patients

Norton, N., Youssef, B., Hillman, D. W., Nassar, A., Geiger, X. J., Necela, B. M., Liu, H., Ruddy, K. J., Polley, M. Y. C., Ingle, J. N., Couch, F. J., Perez, E. A., Liu, M. C., Carter, J. M., Leon-Ferre, R. A., Boughey, J. C., Somers, E. B., Kalari, K. R., Visscher, D. W., Goetz, M. P. & 1 others, Knutson, K. L., Dec 1 2020, In : npj Breast Cancer. 6, 1, 4.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Health-Related Quality of Life in MONARCH 3: Abemaciclib plus an Aromatase Inhibitor as Initial Therapy in HR+, HER2− Advanced Breast Cancer

Goetz, M. P., Martin, M., Tokunaga, E., Park, I. H., Huober, J., Toi, M., Stoffregen, C., Shekarriz, S., Andre, V., Gainford, M. C., Price, G. L. & Johnston, S., Sep 1 2020, In : Oncologist. 25, 9, p. e1346-e1354

Research output: Contribution to journalArticle

Open Access

Multidisciplinary management of breast cancer with extensive regional nodal involvement

Smith, B. D., Goetz, M. P. & Boughey, J. C., Jul 10 2020, In : Journal of Clinical Oncology. 38, 20, p. 2290-2299 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Optimized immunohistochemical detection of estrogen receptor beta using two validated monoclonal antibodies confirms its expression in normal and malignant breast tissues

Hawse, J. R., Carter, J. M., Aspros, K. G. M., Bruinsma, E. S., Koepplin, J. W., Negron, V., Subramaniam, M., Ingle, J. N., Rech, K. L. & Goetz, M. P., Jan 1 2020, In : Breast Cancer Research and Treatment. 179, 1, p. 241-249 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Patient-Reported Cognitive Impairment among Women with Early Breast Cancer Randomly Assigned to Endocrine Therapy Alone Versus Chemoendocrine Therapy: Results from TAILORx

Wagner, L. I., Gray, R. J., Sparano, J. A., Whelan, T. J., Garcia, S. F., Yanez, B., Tevaarwerk, A. J., Carlos, R. C., Albain, K. S., Olson, J. A., Goetz, M. P., Pritchard, K. I., Hayes, D. F., Geyer, C. E., Dees, E. C., McCaskill-Stevens, W. J., Minasian, L. M., Sledge, G. W. & Cella, D., Apr 9 2020, In : Journal of Clinical Oncology. 38, 17, p. 1875-1886 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Pharmacogenomics of aromatase inhibitors in postmenopausal breast cancer and additional mechanisms of anastrozole action

Cairns, J., Ingle, J. N., Dudenkov, T. M., Kalari, K. R., Carlson, E. E., Na, J., Buzdar, A. U., Robson, M. E., Ellis, M. J., Goss, P. E., Shepherd, L. E., Goodnature, B., Goetz, M. P., Weinshilboum, R. M., Li, H., Bari, M. G. & Wang, L., Aug 20 2020, In : JCI Insight. 5, 16

Research output: Contribution to journalArticle

Open Access

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

the International Immuno-Oncology Biomarker Working Group, Dec 1 2020, In : npj Breast Cancer. 6, 1, 17.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Regulation of sister chromatid cohesion by nuclear PD-L1

Yu, J., Qin, B., Moyer, A. M., Nowsheen, S., Tu, X., Dong, H., Boughey, J. C., Goetz, M. P., Weinshilboum, R., Lou, Z. & Wang, L., Jul 1 2020, In : Cell Research. 30, 7, p. 590-601 12 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

TBCRC023: A randomized phase II neoadjuvant trial of lapatinib plus trastuzumab without chemotherapy for 12 versus 24 weeks in patients with HER2-positive breast cancer

on behalf of the Translational Breast Cancer Research Consortium, Feb 15 2020, In : Clinical Cancer Research. 26, 4, p. 821-827 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
2019

A combinatorial biomarker predicts pathologic complete response to neoadjuvant lapatinib and trastuzumab without chemotherapy in patients with HER2+ breast cancer

Veeraraghavan, J., De Angelis, C., Mao, R., Wang, T., Herrera, S., Pavlick, A. C., Contreras, A., Nuciforo, P., Mayer, I. A., Forero, A., Nanda, R., Goetz, M. P., Chang, J. C., Wolff, A. C., Krop, I. E., Fuqua, S. A. W., Prat, A., Hilsenbeck, S. G., Weigelt, B., Reis-Filho, J. S. & 4 others, Gutierrez, C., Osborne, C. K., Rimawi, M. F. & Schiff, R., Jun 1 2019, In : Annals of Oncology. 30, 6, p. 927-933 7 p., mdz076.

Research output: Contribution to journalArticle

14 Scopus citations

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2

Dudenkov, T. M., Liu, D., Cairns, J., Devarajan, S., Zhuang, Y., Ingle, J. N., Buzdar, A. U., Robson, M. E., Kubo, M., Batzler, A., Barman, P., Jenkins, G. D., Carlson, E. E., Goetz, M. P., Northfelt, D. W., Moreno-Aspitia, A., Desta, Z., Reid, J. M., Kalari, K. R., Wang, L. & 1 others, Weinshilboum, R. M., Jul 2019, In : Clinical pharmacology and therapeutics. 106, 1, p. 219-227 9 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
1 Scopus citations

Breast cancer, version 3.2018 featured updates to the NCCN guidelines

Goetz, M. P., Gradishar, W. J., Anderson, B. O., Abraham, J., Aft, R., Allison, K. H., Blair, S. L., Burstein, H. J., Dang, C., Elias, A. D., Farrar, W. B., Giordano, S. H., Goldstein, L. J., Isakoff, S. J., Lyons, J., Kelly Marcom, P., Mayer, I. A., Moran, M. S., Mortimer, J., O’Regan, R. M. & 13 others, Patel, S. A., Pierce, L. J., Reed, E. C., Rugo, H. S., Sitapati, A., Smith, K. L., Smith, M. L., Soliman, H., Telli, M. L., Ward, J. H., Young, J. S., Shead, D. A. & Kumar, R., Feb 2019, In : JNCCN Journal of the National Comprehensive Cancer Network. 17, 2, p. 118-126 9 p.

Research output: Contribution to journalArticle

Open Access
53 Scopus citations

Clinical and genomic risk to guide the use of adjuvant therapy for breast cancer

Sparano, J. A., Gray, R. J., Ravdin, P. M., Makower, D. F., Pritchard, K. I., Albain, K. S., Hayes, D. F., Geyer, C. E., Dees, E. C., Goetz, M. P., Olson, J. A., Lively, T., Badve, S. S., Saphner, T. J., Wagner, L. I., Whelan, T. J., Ellis, M. J., Paik, S., Wood, W. C., Keane, M. M. & 10 others, Gomez Moreno, H. L., Reddy, P. S., Goggins, T. F., Mayer, I. A., Brufsky, A. M., Toppmeyer, D. L., Kaklamani, V. G., Berenberg, J. L., Abrams, J. & Sledge, G. W., Jun 20 2019, In : New England Journal of Medicine. 380, 25, p. 2395-2405 11 p.

Research output: Contribution to journalArticle

69 Scopus citations

Comparison of 99mTc-sestamibi molecular breast imaging and breast MRI in patients with invasive breast cancer receiving neoadjuvant chemotherapy

Hunt, K. N., Conners, A. L., Goetz, M. P., O’Connor, M. K., Suman, V., Kalari, K., Weinshilboum, R., Wang, L., Carter, J., McLaughlin, S. A., Aspitia, A. M., Gray, R. J., Northfelt, D. & Boughey, J. C., Jan 1 2019, In : American Journal of Roentgenology. 213, 4, p. 932-943 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Deep sequencing across germline genome-wide association study signals relating to breast cancer events in women receiving aromatase inhibitors for adjuvant therapy of early breast cancer

Ingle, J. N., Kalari, K. R., Momozawa, Y., Kubo, M., Furukawa, Y., Shepherd, L. E., Ellis, M. J., Goss, P. E., Barman, P., Carlson, E. E., Sinnwell, J. P., Tang, X., Goetz, M. P., Chen, B. E., Cairns, J., Weinshilboum, R. M. & Wang, L., Oct 1 2019, In : Pharmacogenetics and genomics. 29, 8, p. 183-191 9 p.

Research output: Contribution to journalArticle

Metaplastic breast cancer has a poor response to neoadjuvant systemic therapy

Al-Hilli, Z., Choong, G., Keeney, M. G., Visscher, D. W., Ingle, J. N., Goetz, M. P. & Jakub, J. W., Aug 15 2019, In : Breast Cancer Research and Treatment. 176, 3, p. 709-716 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

MONARCH 3 final PFS: a randomized study of abemaciclib as initial therapy for advanced breast cancer

Johnston, S., Martin, M., Di Leo, A., Im, S. A., Awada, A., Forrester, T., Frenzel, M., Hardebeck, M. C., Cox, J., Barriga, S., Toi, M., Iwata, H. & Goetz, M. P., Dec 1 2019, In : npj Breast Cancer. 5, 1, 5.

Research output: Contribution to journalArticle

Open Access
48 Scopus citations

Spontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall

Moyer, A. M., Yu, J., Sinnwell, J. P., Dockter, T. J., Suman, V. J., Weinshilboum, R. M., Boughey, J. C., Goetz, M. P., Visscher, D. W. & Wang, L., 2019, In : Oncotarget. 10, 39, p. 3924-3930 7 p.

Research output: Contribution to journalArticle

Open Access

The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1

Cairns, J., Ingle, J. N., Kalari, K. R., Shepherd, L. E., Kubo, M., Goetz, M. P., Weinshilboum, R. M. & Wang, L., Apr 3 2019, In : Breast Cancer Research. 21, 1, 47.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations
2018

Adjuvant chemotherapy guided by a 21-gene expression assay in breast cancer

Sparano, J. A., Gray, R. J., Makower, D. F., Pritchard, K. I., Albain, K. S., Hayes, D. F., Geyer, C. E., Dees, E. C., Goetz, M. P., Olson, J. A., Lively, T., Badve, S. S., Saphner, T. J., Wagner, L. I., Whelan, T. J., Ellis, M. J., Paik, S., Wood, W. C., Ravdin, P. M., Keane, M. M. & 10 others, Gomez Moreno, H. L., Reddy, P. S., Goggins, T. F., Mayer, I. A., Brufsky, A. M., Toppmeyer, D. L., Kaklamani, V. G., Berenberg, J. L., Abrams, J. & Sledge, G. W., Jul 12 2018, In : New England Journal of Medicine. 379, 2, p. 111-121 11 p.

Research output: Contribution to journalArticle

469 Scopus citations

ATR inhibition is a promising radiosensitizing strategy for triple-negative breast cancer

Tu, X., Kahila, M. M., Zhou, Q., Yu, J., Kalari, K. R., Wang, L., Harmsen, W. S., Yuan, J., Boughey, J. C., Goetz, M. P., Sarkaria, J. N., Lou, Z. & Mutter, R. W., Nov 2018, In : Molecular cancer therapeutics. 17, 11, p. 2462-2472 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Carnitine Palmitoyltransferase 1A Has a Lysine Succinyltransferase Activity

Kurmi, K., Hitosugi, S., Wiese, E. K., Boakye-Agyeman, F., Gonsalves, W. I., Lou, Z., Karnitz, L. M., Goetz, M. P. & Hitosugi, T., Feb 6 2018, In : Cell reports. 22, 6, p. 1365-1373 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy

Goetz, M. P., Sangkuhl, K., Guchelaar, H. J., Schwab, M., Province, M., Whirl-Carrillo, M., Symmans, W. F., McLeod, H. L., Ratain, M. J., Zembutsu, H., Gaedigk, A., van Schaik, R. H., Ingle, J. N., Caudle, K. E. & Klein, T. E., May 2018, In : Clinical pharmacology and therapeutics. 103, 5, p. 770-777 8 p.

Research output: Contribution to journalArticle

77 Scopus citations

Clinical practice guidelines in oncology

Gradishar, W. J., Anderson, B. O., Balassanian, R., Blair, S. L., Burstein, H. J., Cyr, A., Elias, A. D., Farrar, W. B., Forero, A., Giordano, S. H., Goetz, M. P., Goldstein, L. J., Isakoff, S. J., Lyons, J., Kelly Marcom, P., Mayer, I. A., McCormick, B., Moran, M. S., O’Regan, R. M., Patel, S. A. & 13 others, Pierce, L. J., Reed, E. C., Salerno, K. E., Schwartzberg, L. S., Sitapati, A., Smith, K. L., Smith, M. L., Soliman, H., Somlo, G., Telli, M. L., Ward, J. H., Kumar, R. & Shead, D. A., Mar 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 3, p. 310-320 11 p.

Research output: Contribution to journalArticle

120 Scopus citations

Discovery of a glucocorticoid receptor (gr) activity signature using selective gr antagonis in er-negative breast cancer

West, D. C., Kocherginsky, M., Tonsing-Carter, E. Y., Dolcen, D. N., Hosfield, D. J., Lastra, R. R., Sinnwell, J. P., Thompson, K. J., Bowie, K. R., Harkless, R. V., Skor, M. N., Pierce, C. F., Styke, S. C., Kim, C. R., De Wet, L., Greene, G. L., Boughey, J. C., Goetz, M. P., Kalari, K. R., Wang, L. & 3 others, Fleming, G. F., Gyorffy, B. & Conzen, S. D., Jul 15 2018, In : Clinical Cancer Research. 24, 14, p. 3433-3446 14 p.

Research output: Contribution to journalArticle

10 Scopus citations

DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine

Yu, J., Qin, B., Moyer, A. M., Nowsheen, S., Liu, T., Qin, S., Zhuang, Y., Liu, D., Lu, S. W., Kalari, K. R., Visscher, D. W., Copland, J. A., McLaughlin, S. A., Moreno-Aspitia, A., Northfelt, D. W., Gray, R. J., Lou, Z., Suman, V. J., Weinshilboum, R., Boughey, J. C. & 2 others, Goetz, M. P. & Wang, L., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2376-2388 13 p.

Research output: Contribution to journalArticle

34 Scopus citations

ERβ-mediated induction of cystatins results in suppression of TGFβ signaling and inhibition of triple-negative breast cancer metastasis

Reese, J. M., Bruinsma, E. S., Nelson, A. W., Chernukhin, I., Carroll, J. S., Li, Y., Subramaniam, M., Suman, V. J., Negron, V., Monroe, D. G., Ingle, J. N., Goetz, M. P. & Hawse, J. R., Oct 9 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 41, p. E9580-E9589

Research output: Contribution to journalArticle

12 Scopus citations

Germline genome-wide association studies in women receiving neoadjuvant chemotherapy with or without bevacizumab

Ingle, J. N., Kalari, K. R., Wickerham, D. L., Von Minckwitz, G., Fasching, P. A., Furukawa, Y., Mushiroda, T., Goetz, M. P., Barman, P., Carlson, E. E., Rastogi, P., Costantino, J. P., Cairns, J., Paik, S., Bear, H. D., Kubo, M., Wang, L., Wolmark, N. & Weinshilboum, R. M., 2018, In : Pharmacogenetics and genomics. 28, 6, p. 147-152 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Low PETN levels and PIK3CA mutations predict resistance to neoadjuvant lapatinib and trastuzumab without chemotherapy in patients with HER2 over-expressing breast cancer

Rimawi, M. F., de Angelis, C., Contreras, A., Pareja, F., Geyer, F. C., Burke, K. A., Herrera, S., Wang, T., Mayer, I. A., Forero, A., Nanda, R., Goetz, M. P., Chang, J. C., Krop, I. E., Wolff, A. C., Pavlick, A. C., Fuqua, S. A. W., Gutierrez, C., Hilsenbeck, S. G., Li, M. M. & 4 others, Weigelt, B., Reis-Filho, J. S., Osborne, C. K. & Schiff, R., Nov 7 2018, In : Breast Cancer Research and Treatment. 167, 3, p. 731-740 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Management of abemaciclib associated adverse events in patients with hormone receptor positive (HR+), HER2- advanced breast cancer: Analysis of the MONARCH trials

Rugo, H. S., Tolaney, S. M., Huober, J., Toi, M., André, V., Barriga, S., Forrester, T., Sledge, G. W. & Goetz, M. P., Oct 1 2018, In : Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. viii110-viii111

Research output: Contribution to journalArticle

Open Access

NOTCH3 expression is linked to breast cancer seeding and distant metastasis

Leontovich, A. A., Jalalirad, M., Salisbury, J. L., Mills, L., Haddox, C., Schroeder, M., Tuma, A., Guicciardi, M. E., Zammataro, L., Gambino, M. W., Amato, A., Di Leonardo, A., McCubrey, J., Lange, C. A., Liu, M., Haddad, T., Goetz, M., Boughey, J., Sarkaria, J., Wang, L. & 3 others, Ingle, J. N., Galanis, E. & D'Assoro, A. B., Sep 4 2018, In : Breast Cancer Research. 20, 1, 105.

Research output: Contribution to journalArticle

14 Scopus citations

PANOPLY: Omics-guided drug prioritization method tailored to an individual patient

Kalari, K. R., Sinnwell, J. P., Thompson, K. J., Tang, X., Carlson, E. E., Yu, J., Vedell, P. T., Ingle, J. N., Weinshilboum, R. M., Boughey, J. C., Wang, L., Goetz, M. P. & Suman, V., 2018, In : JCO Clinical Cancer Informatics. 2018, 2, p. 1-12 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

PATINA: A randomized, open label, phase III trial to evaluate the efficacy and safety of palbociclib + Anti-HER2 therapy + endocrine therapy (ET) vs. anti-HER2 therapy + ET after induction treatment for hormone receptor positive (HR+)/HER2-positive metastatic breast cancer (MBC)

Loibl, S., Metzger, O., Mandrekar, S. J., Mundhenke, C., Seiler, S., Valagussa, P., DeMichele, A., Lim, E., Tripathy, D., Winer, E. P., Huang, C., Carey, L., Francis, P., Miller, K. D., Goetz, M. P., Prat, A., Loi, S., Krop, I., Gianni, L. & Ciruelos, E. M., Oct 1 2018, In : Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. viii121

Research output: Contribution to journalArticle

Open Access

Phase i trial to evaluate the addition of alisertib to fulvestrant in women with endocrine-resistant, ER+ metastatic breast cancer

Haddad, T. C., D’Assoro, A., Suman, V., Opyrchal, M., Peethambaram, P., Liu, M. C., Goetz, M. P. & Ingle, J. N., Dec 30 2018, In : Breast Cancer Research and Treatment. 168, 3, p. 639-647 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Prognostic characteristics in hormone receptor-positive advanced breast cancer and characterization of abemaciclib efficacy

Di Leo, A., O’Shaughnessy, J., Sledge, G. W., Martin, M., Lin, Y., Frenzel, M., Hardebeck, M. C., Smith, I. C., Llombart-Cussac, A., Goetz, M. P. & Johnston, S., Dec 1 2018, In : npj Breast Cancer. 4, 1, 41.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Tailoring adjuvant endocrine therapy for premenopausal breast cancer

Francis, P. A., Pagani, O., Fleming, G. F., Walley, B. A., Colleoni, M., Láng, I., Gómez, H. L., Tondini, C., Ciruelos, E., Burstein, H. J., Bonnefoi, H. R., Bellet, M., Martino, S., Geyer, C. E., Goetz, M. P., Stearns, V., Pinotti, G., Puglisi, F., Spazzapan, S., Climent, M. A. & 16 others, Pavesi, L., Ruhstaller, T., Davidson, N. E., Coleman, R., Debled, M., Buchholz, S., Ingle, J. N., Winer, E. P., Maibach, R., Rabaglio-Poretti, M., Ruepp, B., Di Leo, A., Coates, A. S., Gelber, R. D., Goldhirsch, A. & Regan, M. M., Jul 12 2018, In : New England Journal of Medicine. 379, 2, p. 122-137 16 p.

Research output: Contribution to journalArticle

121 Scopus citations

Tumor and serum DNA methylation in women receiving preoperative chemotherapy with or without vorinostat in TBCRC008

Connolly, R. M., Fackler, M. J., Zhang, Z., Zhou, X. C., Goetz, M. P., Boughey, J. C., Walsh, B., Carpenter, J. T., Storniolo, A. M., Watkins, S. P., Gabrielson, E. W., Stearns, V. & Sukumar, S., Jan 1 2018, In : Breast Cancer Research and Treatment. 167, 1, p. 107-116 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway

Kurmi, K., Hitosugi, S., Yu, J., Boakye-Agyeman, F., Wiese, E. K., Larson, T. R., Dai, Q., Machida, Y. J., Lou, Z., Wang, L., Boughey, J. C., Kaufmann, S. H., Goetz, M. P., Karnitz, L. M. & Hitosugi, T., Dec 4 2018, In : Cell Metabolism. 28, 6, p. 833-847.e8

Research output: Contribution to journalArticle

8 Scopus citations
2017

A comprehensive analysis of breast cancer microbiota and host gene expression

Thompson, K. J., Ingle, J. N., Tang, X., Chia, N., Jeraldo, P. R., Walther-Antonio, M. R., Kandimalla, K. K., Johnson, S., Yao, J. Z., Harrington, S. C., Suman, V. J., Wang, L., Weinshilboum, R. L., Boughey, J. C., Kocher, J. P., Nelson, H., Goetz, M. P. & Kalari, K. R., Nov 2017, In : PloS one. 12, 11, e0188873.

Research output: Contribution to journalArticle

20 Scopus citations

A phase II trial of neoadjuvant MK-2206, an AKT inhibitor, with anastrozole in clinical stage II or III PIK3CA-mutant ER-positive and HER2-negative breast cancer

Ma, C. X., Suman, V., Goetz, M. P., Northfelt, D., Burkard, M. E., Ademuyiwa, F., Naughton, M., Margenthaler, J., Aft, R., Gray, R., Tevaarwerk, A., Wilke, L., Haddad, T., Moynihan, T., Loprinzi, C., Hieken, T., Barnell, E. K., Skidmore, Z. L., Feng, Y. Y., Krysiak, K. & 14 others, Hoog, J., Guo, Z., Nehring, L., Wisinski, K. B., Mardis, E., Hagemann, I. S., Vij, K., Sanati, S., Al-Kateb, H., Griffith, O. L., Griffith, M., Doyle, L., Erlichman, C. & Ellis, M. J., Nov 15 2017, In : Clinical Cancer Research. 23, 22, p. 6823-6832 10 p.

Research output: Contribution to journalArticle

34 Scopus citations