• 5189 Citations
  • 40 Scopus h-Index
1991 …2020

Research output per year

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Research Output

  • 5189 Citations
  • 40 Scopus h-Index
  • 177 Article
  • 3 Comment/debate
  • 1 Chapter
  • 1 Review article
2020

Better stress coping associated with lower tau in amyloid-positive cognitively unimpaired older adults

Arenaza-Urquijo, E. M., Przybelski, S. A., Machulda, M. M., Knopman, D. S., Lowe, V. J., Mielke, M. M., Reddy, A. L., Geda, Y. E., Jack, C. R., Petersen, R. C. & Vemuri, P., Apr 14 2020, In : Neurology. 94, 15, p. E1571-E1579

Research output: Contribution to journalArticle

Open Access

Brain amyloid, cortical thickness, and changes in activities of daily living

Vassilaki, M., Aakre, J. A., Kremers, W. K., Lesnick, T. G., Mielke, M. M., Geda, Y. E., Machulda, M. M., Knopman, D. S., Butler, L., Traber, M., Vemuri, P., Lowe, V. J., Jack, C. R., Roberts, R. O. & Petersen, R. C., Jan 1 2020, (Accepted/In press) In : Annals of Clinical and Translational Neurology.

Research output: Contribution to journalArticle

Open Access
Open Access

Cortical atrophy patterns of incident MCI subtypes in the Mayo Clinic Study of Aging

Machulda, M. M., Lundt, E. S., Albertson, S. M., Spychalla, A. J., Schwarz, C. G., Mielke, M. M., Jack, C. R., Kremers, W. K., Vemuri, P., Knopman, D. S., Jones, D. T., Bondi, M. W. & Petersen, R. C., Jan 1 2020, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Open Access

Imaging Biomarkers of Alzheimer Disease in Multiple Sclerosis

Zeydan, B., Lowe, V. J., Reichard, R. R., Przybelski, S. A., Lesnick, T. G., Schwarz, C. G., Senjem, M. L., Gunter, J. L., Parisi, J. E., Machulda, M. M., Vemuri, P., Mielke, M. M., Knopman, D. S., Petersen, R. C., Jack, C. R., Kantarci, O. H. & Kantarci, K., Apr 1 2020, In : Annals of neurology. 87, 4, p. 556-567 12 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Ioflupane 123I (DAT scan) SPECT identifies dopamine receptor dysfunction early in the disease course in progressive apraxia of speech

Seckin, Z. I., Whitwell, J. L., Utianski, R. L., Botha, H., Ali, F., Duffy, J. R., Clark, H. M., Machulda, M. M., Jordan, L. G., Min, H. K., Lowe, V. J. & Josephs, K. A., Jan 1 2020, (Accepted/In press) In : Journal of Neurology.

Research output: Contribution to journalArticle

Longitudinal amyloid-β PET in atypical Alzheimer's disease and frontotemporal lobar degeneration

Whitwell, J. L., Tosakulwong, N., Weigand, S. D., Graff-Radford, J., Duffy, J. R., Clark, H. M., Machulda, M. M., Botha, H., Utianski, R. L., Schwarz, C. G., Senjem, M. L., Strand, E., Ertekin-Taner, N., Jack, C. R., Lowe, V. J. & Josephs, K. A., Jan 1 2020, In : Journal of Alzheimer's Disease. 74, 1, p. 377-389 13 p.

Research output: Contribution to journalArticle

Open Access

Neuroanatomical correlates of phonologic errors in logopenic progressive aphasia

Petroi, D., Duffy, J. R., Borgert, A., Strand, E. A., Machulda, M. M., Senjem, M. L., Jack, C. R., Josephs, K. A. & Whitwell, J. L., May 2020, In : Brain and Language. 204, 104773.

Research output: Contribution to journalArticle

Pick’s disease: clinicopathologic characterization of 21 cases

Choudhury, P., Scharf, E. L., Paolini, M. A., Graff-Radford, J., Alden, E. C., Machulda, M. M., Jones, D. T., Fields, J. A., Murray, M. E., Graff-Radford, N. R., Constantopoulos, E., Reichard, R. R., Knopman, D. S., Duffy, J. R., Dickson, D. W., Parisi, J. E., Josephs, K. A., Petersen, R. C. & Boeve, B. F., Jan 1 2020, (Accepted/In press) In : Journal of Neurology.

Research output: Contribution to journalArticle

Relationship Between Risk Factors and Brain Reserve in Late Middle Age: Implications for Cognitive Aging

Neth, B. J., Graff-Radford, J., Mielke, M. M., Przybelski, S. A., Lesnick, T. G., Schwarz, C. G., Reid, R. I., Senjem, M. L., Lowe, V. J., Machulda, M. M., Petersen, R. C., Jr, C. R. J., Knopman, D. S. & Vemuri, P., Jan 9 2020, In : Frontiers in Aging Neuroscience. 11, 355.

Research output: Contribution to journalArticle

Open Access

REM sleep atonia loss distinguishes synucleinopathy in older adults with cognitive impairment

McCarter, S. J., Tabatabai, G. M., Jong, H. Y., Sandness, D. J., Timm, P. C., Johnson, K. L., McCarter, A. R., Savica, R., Vemuri, P., Machulda, M. M., Kantarci, K., Mielke, M. M., Boeve, B. F., Silber, M. H. & St Louis, E. K., Jan 7 2020, In : Neurology. 94, 1, p. e15-e29

Research output: Contribution to journalArticle

1 Scopus citations
2019

Amyloid, Vascular, and Resilience Pathways Associated with Cognitive Aging

Vemuri, P., Lesnick, T. G., Knopman, D. S., Przybelski, S. A., Reid, R. I., Mielke, M. M., Graff-Radford, J., Lowe, V. J., Machulda, M. M., Petersen, R. C. & Jack, C. R., Jan 1 2019, (Accepted/In press) In : Annals of neurology.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

An Evaluation of the Progressive Supranuclear Palsy Speech/Language Variant

Whitwell, J. L., Stevens, C. A., Duffy, J. R., Clark, H. M., Machulda, M. M., Strand, E., Martin, P. R., Utianski, R. L., Botha, H., Spychalla, A. J., Senjem, M. L., Schwarz, C. G., Jack, C. R., Ali, F., Hassan, A. & Josephs, K. A., Jul 2019, In : Movement Disorders Clinical Practice. 6, 6, p. 452-461 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Association of non-exercise physical activity in mid- and late-life with cognitive trajectories and the impact of APOE ε4 genotype status: the Mayo Clinic Study of Aging

Krell-Roesch, J., Syrjanen, J. A., Vassilaki, M., Barisch-Fritz, B., Trautwein, S., Boes, K., Woll, A., Kremers, W. K., Machulda, M. M., Mielke, M. M., Knopman, D. S., Petersen, R. C. & Geda, Y. E., Dec 1 2019, In : European Journal of Ageing. 16, 4, p. 491-502 12 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Cardiometabolic Health and Longitudinal Progression of White Matter Hyperintensity: The Mayo Clinic Study of Aging

Scharf, E. L., Graff-Radford, J., Przybelski, S. A., Lesnick, T. G., Mielke, M. M., Knopman, D. S., Preboske, G. M., Schwarz, C. G., Senjem, M. L., Gunter, J. L., Machulda, M., Kantarci, K., Petersen, R. C., Jack, C. R. & Vemuri, P., Nov 1 2019, In : Stroke. 50, 11, p. 3037-3044 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Cerebrospinal fluid dynamics disorders: Relationship to Alzheimer biomarkers and cognition

Graff-Radford, J., Gunter, J. L., Jones, D. T., Przybelski, S. A., Schwarz, C. G., Huston, J., Lowe, V., Elder, B. D., MacHulda, M. M., Gunter, N. B., Petersen, R. C., Kantarci, K., Vemuri, P., Mielke, M. M., Knopman, D. S., Graff-Radford, N. R. & Jack, C. R., Dec 10 2019, In : Neurology. 93, 24, p. E2237-E2246

Research output: Contribution to journalArticle

Clinical and neuroimaging characteristics of clinically unclassifiable primary progressive aphasia

Utianski, R. L., Botha, H., Martin, P. R., Schwarz, C. G., Duffy, J. R., Clark, H. M., Machulda, M. M., Butts, A. M., Lowe, V. J., Jack, C. R., Senjem, M. L., Spychalla, A. J., Whitwell, J. L. & Josephs, K. A., Oct 1 2019, In : Brain and Language. 197, 104676.

Research output: Contribution to journalArticle

2 Scopus citations
1 Scopus citations
1 Scopus citations

Comparison of variables associated with cerebrospinal fluid neurofilament, total-tau, and neurogranin

Mielke, M. M., Syrjanen, J. A., Blennow, K., Zetterberg, H., Skoog, I., Vemuri, P., Machulda, M. M., Graff-Radford, J., Knopman, D. S., Jack, C. R., Petersen, R. C. & Kern, S., Nov 2019, In : Alzheimer's and Dementia. 15, 11, p. 1437-1447 11 p.

Research output: Contribution to journalArticle

Cortical β-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging

Krell-Roesch, J., Vassilaki, M., Mielke, M. M., Kremers, W. K., Lowe, V. J., Vemuri, P., Machulda, M. M., Christianson, T. J., Syrjanen, J. A., Stokin, G. B., Butler, L. M., Traber, M., Jack, C. R., Knopman, D. S., Roberts, R. O., Petersen, R. C. & Geda, Y. E., Dec 1 2019, In : Translational psychiatry. 9, 1, 123.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Cross-sectional associations of tau-PET signal with cognition in cognitively unimpaired adults

Lowe, V. J., Bruinsma, T. J., Wiste, H. J., Min, H. K., Weigand, S. D., Fang, P., Senjem, M. L., Therneau, T. M., Boeve, B. F., Josephs, K. A., Pandey, M. K., Murray, M. E., Kantarci, K., Jones, D. T., Vemuri, P., Graff-Radford, J., Schwarz, C. G., Machulda, M. M., Mielke, M. M., Roberts, R. O. & 3 others, Knopman, D. S., Petersen, R. C. & Jack, C. R., Jul 2 2019, In : Neurology. 93, 1, p. e29-e39

Research output: Contribution to journalArticle

6 Scopus citations
18 Scopus citations
1 Scopus citations

Functional activity and neuropsychiatric symptoms in normal aging and mild cognitive impairment: The Mayo clinic study of aging

Krell-Roesch, J., Cerhan, L. P., MacHulda, M. M., Roberts, R. O., Mielke, M. M., Knopman, D. S., Syrjanen, J. A., Christianson, T. J., Petersen, R. C. & Geda, Y. E., Jan 1 2019, In : Alzheimer disease and associated disorders. 33, 1, p. 68-71 4 p.

Research output: Contribution to journalArticle

Informant-based hearing difficulties and the risk for mild cognitive impairment and dementia

Vassilaki, M., Aakre, J. A., Knopman, D. S., Kremers, W. K., Mielke, M. M., Geda, Y. E., Machulda, M. M., Al Fakir, R., Undavalli, C., Roberts, R. O. & Petersen, R. C., Nov 1 2019, In : Age and Ageing. 48, 6, p. 888-894 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Longitudinal tau-PET uptake and atrophy in atypical Alzheimer's disease

Sintini, I., Martin, P. R., Graff-Radford, J., Senjem, M. L., Schwarz, C. G., Machulda, M. M., Spychalla, A. J., Drubach, D. A., Knopman, D. S., Petersen, R. C., Lowe, V. J., Jack, C. R., Josephs, K. A. & Whitwell, J. L., 2019, In : NeuroImage: Clinical. 23, 101823.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2 Scopus citations

Plasma and CSF neurofilament light: Relation to longitudinal neuroimaging and cognitive measures

Mielke, M. M., Syrjanen, J. A., Blennow, K., Zetterberg, H., Vemuri, P., Skoog, I., Machulda, M. M., Kremers, W. K., Knopman, D. S., Jack, C., Petersen, R. C. & Kern, S., Jul 16 2019, In : Neurology. 93, 3, p. E252-E260

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Predicting Progression to Mild Cognitive Impairment

Petersen, R. C., Lundt, E. S., Therneau, T. M., Weigand, S. D., Knopman, D. S., Mielke, M. M., Roberts, R. O., Lowe, V., Machulda, M. M., Kremers, W. K., Geda, Y. E. & Jack, C. R. J., Jan 1 2019, In : Annals of Neurology. 85, 1, p. 155-160 6 p.

Research output: Contribution to journalArticle

10 Scopus citations
18 Scopus citations

Progressive agrammatic aphasia without apraxia of speech as a distinct syndrome

Tetzloff, K. A., Duffy, J. R., Clark, H. M., Utianski, R. L., Strand, E., Machulda, M. M., Botha, H., Martin, P. R., Schwarz, C. G., Senjem, M. L., Reid, R. I., Gunter, J. L., Spychalla, A. J., Knopman, D. S., Petersen, R. C., Jack, C. R., Lowe, V. J., Josephs, K. A. & Whitwell, J. L., Aug 1 2019, In : Brain. 142, 8, p. 2466-2482 17 p.

Research output: Contribution to journalArticle

2 Scopus citations

Quantity and quality of mental activities and the risk of incident mild cognitive impairment

Krell-Roesch, J., Syrjanen, J. A., Vassilaki, M., MacHulda, M. M., Mielke, M. M., Knopman, D. S., Kremers, W. K., Petersen, R. C. & Geda, Y. E., Aug 6 2019, In : Neurology. 93, 6, p. E548-E558

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Regional multimodal relationships between tau, hypometabolism, atrophy, and fractional anisotropy in atypical Alzheimer's disease

Sintini, I., Schwarz, C. G., Martin, P. R., Graff-Radford, J., Machulda, M. M., Senjem, M. L., Reid, R. I., Spychalla, A. J., Drubach, D. A., Lowe, V. J., Jack, C. R., Josephs, K. A. & Whitwell, J. L., Apr 1 2019, In : Human Brain Mapping. 40, 5, p. 1618-1631 14 p.

Research output: Contribution to journalArticle

8 Scopus citations

Sex-specific norms for verbal memory tests may improve diagnostic accuracy of amnestic MCI

Alzheimer's Disease Neuroimaging Initiative, Nov 12 2019, In : Neurology. 93, 20, p. e1881-e1889

Research output: Contribution to journalArticle

2 Scopus citations
Open Access
3 Scopus citations
Open Access
5 Scopus citations
Open Access
3 Scopus citations
16 Scopus citations

The influence of β-amyloid on [ 18 F]AV-1451 in semantic variant of primary progressive aphasia

Whitwell, J. L., Martin, P. R., Duffy, J. R., Clark, H., Machulda, M. M., Schwarz, C., Weigand, S. D., Sintini, I., Senjem, M. L., Taner, N., Botha, H., Utianski, R., Graff-Radford, J., Jones, D. T., Boeve, B. F., Knopman, D. S., Petersen, R. C., Jack, C. R. J., Lowe, V. & Josephs, K. A., Feb 12 2019, In : Neurology. 92, 7, p. e710-e722

Research output: Contribution to journalArticle

3 Scopus citations

The metabolic brain signature of cognitive resilience in the 80+: Beyond Alzheimer pathologies

Arenaza-Urquijo, E. M., Przybelski, S. A., Lesnick, T. L., Graff-Radford, J., MacHulda, M. M., Knopman, D. S., Schwarz, C. G., Lowe, V. J., Mielke, M. M., Petersen, R. C., Jack, C. R. & Vemuri, P., Jan 1 2019, In : Brain. 142, 4, p. 1134-1147 14 p.

Research output: Contribution to journalArticle

7 Scopus citations

The role of age on tau PET uptake and gray matter atrophy in atypical Alzheimer's disease

Whitwell, J. L., Martin, P., Graff-Radford, J., Machulda, M. M., Senjem, M. L., Schwarz, C. G., Weigand, S. D., Spychalla, A. J., Drubach, D. A., Jack, C. R., Lowe, V. J. & Josephs, K. A., May 2019, In : Alzheimer's and Dementia. 15, 5, p. 675-685 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

[18F]AV-1451 clustering of entorhinal and cortical uptake in Alzheimer's disease

Whitwell, J. L., Graff-Radford, J., Tosakulwong, N., Weigand, S. D., Machulda, M. M., Senjem, M. L., Schwarz, C., Spychalla, A. J., Jones, D. T., Drubach, D., Knopman, D. S., Boeve, B. F., Taner, N., Petersen, R. C., Lowe, V., Jack, C. R. J. & Josephs, K. A., Feb 1 2018, In : Annals of Neurology. 83, 2, p. 248-257 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

[18F]AV-1451 tau-PET and primary progressive aphasia

Josephs, K. A., Martin, P. R., Botha, H., Schwarz, C., Duffy, J. R., Clark, H., Machulda, M. M., Graff-Radford, J., Weigand, S. D., Senjem, M. L., Utianski, R., Drubach, D., Boeve, B. F., Jones, D. T., Knopman, D. S., Petersen, R. C., Jack, C. R. J., Lowe, V. & Whitwell, J. L., Jan 1 2018, (Accepted/In press) In : Annals of Neurology.

Research output: Contribution to journalArticle

20 Scopus citations