Martin E Fernandez-Zapico, MD

  • 7877 Citations
  • 40 Scopus h-Index
19982019

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2019

Biology and prognostic impact of clonal plasmacytoid dendritic cells in chronic myelomonocytic leukemia

Lucas, N., Duchmann, M., Rameau, P., Noël, F., Michea, P., Saada, V., Kosmider, O., Pierron, G., Fernandez-Zapico, M. E., Howard, M. T., King, R., Niyongere, S., Diop, M. K., Fenaux, P., Itzykson, R., Willekens, C., Ribrag, V., Fontenay, M., Padron, E., Soumelis, V. & 3 others, Droin, N., Patnaik, M. M. & Solary, E., Jan 1 2019, In : Leukemia.

Research output: Contribution to journalArticle

10 Scopus citations

Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation

Maurel, M., Obacz, J., Avril, T., Ding, Y. P., Papadodima, O., Treton, X., Daniel, F., Pilalis, E., Hörberg, J., Hou, W., Beauchamp, M. C., Tourneur-Marsille, J., Cazals-Hatem, D., Sommerova, L., Samali, A., Tavernier, J., Hrstka, R., Dupont, A., Fessart, D., Delom, F. & 9 others, Fernandez-Zapico, M. E., Jansen, G., Eriksson, L. A., Thomas, D. Y., Jerome-Majewska, L., Hupp, T., Chatziioannou, A., Chevet, E. & Ogier-Denis, E., Jun 2019, In : EMBO Molecular Medicine. 11, 6, e10120.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Derivation of adult canine intestinal organoids for translational research in gastroenterology

Chandra, L., Borcherding, D. C., Kingsbury, D., Atherly, T., Ambrosini, Y. M., Bourgois-Mochel, A., Yuan, W., Kimber, M., Qi, Y., Wang, Q., Wannemuehler, M., Ellinwood, N. M., Snella, E., Martin, M., Skala, M., Meyerholz, D., Estes, M., Fernandez-Zapico, M. E., Jergens, A. E., Mochel, J. P. & 1 others, Allenspach, K., Apr 11 2019, In : BMC Biology. 17, 1, 33.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Direct repression of anoctamin 1 (ANO1) gene transcription by Gli proteins

Mazzone, A., Gibbons, S. J., Eisenman, S. T., Strege, P. R., Zheng, T., D'Amato, M., Ordog, T., Fernandez-Zapico, M. E. & Farrugia, G., May 1 2019, In : FASEB Journal. 33, 5, p. 6632-6642 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming

Koutsioumpa, M., Hatziapostolou, M., Polytarchou, C., Tolosa, E. J., Almada, L. L., Mahurkar-Joshi, S., Williams, J., Tirado-Rodriguez, A. B., Huerta-Yepez, S., Karavias, D., Kourea, H., Poultsides, G. A., Struhl, K., Dawson, D. W., Donahue, T. R., Fernández-Zapico, M. E. & Iliopoulos, D., Jul 1 2019, In : Gut. 68, 7, p. 1271-1286 16 p.

Research output: Contribution to journalArticle

5 Scopus citations

ZIP4 Promotes Muscle Wasting and Cachexia in Mice With Orthotopic Pancreatic Tumors by Stimulating RAB27B-Regulated Release of Extracellular Vesicles From Cancer Cells

Yang, J., Zhang, Z., Zhang, Y., Ni, X., Zhang, G., Cui, X., Liu, M., Xu, C., Zhang, Q., Zhu, H., Yan, J., Zhu, V. F., Luo, Y., Hagan, J. P., Li, Z., Fang, J., Jatoi, A., Fernandez-Zapico, M. E., Zheng, L., Edil, B. H. & 4 others, Bronze, M. S., Houchen, C. W., Li, Y. P. & Li, M., Feb 1 2019, In : Gastroenterology. 156, 3, p. 722-734.e6

Research output: Contribution to journalArticle

17 Scopus citations
2018

CDKN2A germline rare coding variants and risk of pancreatic cancer in minority populations

Mc Williams, R. R., Wieben, E. D., Chaffee, K. G., Antwi, S., Raskin, L., Olopade, O. I., Li, D., Highsmith, W. E. J., Colon-Otero, G., Khanna, L. G., Permuth, J. B., Olson, J. E., Frucht, H., Genkinger, J., Zheng, W., Blot, W. J., Wu, L., Almada, L. L., Fernandez-Zapico, M. E., Sicotte, H. & 2 others, Pedersen, K. S. & Petersen, G. M., Nov 1 2018, In : Cancer Epidemiology Biomarkers and Prevention. 27, 11, p. 1364-1370 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Epigenetics of gastrointestinal diseases: notes from a workshop

Marks, D. L., Olson, R. L., Urrutia, R., Billadeau, D. D., Roy, N., Calin, G. A., Fabbri, M., Koutsioumpa, M., Iliopoulos, D., Ordog, T., Huebert, R. C., Sarmento, O., Bamidele, A. O., Faubion, W. A., Lomberk, G. L., Siveke, J., Ahuja, N., Iovanna, J., Hlady, R. A., Robertson, K. D. & 3 others, Kisiel, J. B., Pin, C. L. & Fernandez-Zapico, M. E., Apr 3 2018, In : Epigenetics. 13, 4, p. 449-457 9 p.

Research output: Contribution to journalArticle

Stromal Gli signaling regulates the activity and differentiation of prostate stem and progenitor cells

Li, Q., Alsaidan, O. A., Rai, S., Wu, M., Shen, H., Beharry, Z., Almada, L. L., Fernandez-Zapico, M. E., Wang, L. & Cai, H., Jul 6 2018, In : Journal of Biological Chemistry. 293, 27, p. 10547-10560 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

ZIP4 promotes pancreatic cancer progression by repressing ZO-1 and claudin-1 through a ZEB1-dependent transcriptional mechanism

Liu, M., Yang, J., Zhang, Y., Zhou, Z., Cui, X., Zhang, L., Fung, K. M., Zheng, W., Allard, F. D., Yee, E. U., Ding, K., Wu, H., Liang, Z., Zheng, L., Fernandez-Zapico, M. E., Li, Y. P., Bronze, M. S., Morris, K. T., Postier, R. G., Houchen, C. W. & 2 others, Yang, J. & Li, M., Jul 1 2018, In : Clinical Cancer Research. 24, 13, p. 3186-3196 11 p.

Research output: Contribution to journalArticle

11 Scopus citations
2017

Experience with precision genomics and tumor board, indicates frequent target identification, but barriers to delivery

Bryce, A. H., Egan, J. B., Borad, M. J., Keith Stewart, A., Nowakowski, G. S., Chanan-Khan, A., Patnaik, M. M., Ansell, S. M., Banck, M. S., Robinson, S. I., Mansfield, A. S., Klee, E. W., Oliver, G. R., McCormick, J. B., Huneke, N. E., Tagtow, C. M., Jenkins, R. B., Rumilla, K. M., Kerr, S. E., Kocher, J. P. A. & 5 others, Beck, S. A., Fernandez-Zapico, M. E., Farrugia, G., Lazaridis, K. N. & McWilliams, R. R., Jan 1 2017, In : Oncotarget. 8, 16, p. 27145-27154 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

IKBKE is required during KRAS-induced pancreatic tumorigenesis

Rajurkar, M., Dang, K., Fernandez-Barrena, M. G., Liu, X., Fernandez-Zapico, M. E., Lewis, B. C. & Mao, J., Jan 15 2017, In : Cancer Research. 77, 2, p. 320-329 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Transcriptional activation of HIF-1 by a ROSERK axis underlies the resistance to photodynamic therapy

Lamberti, M. J., Pansa, M. F., Vera, R. E., Fernandez-Zapico, M. E., Vittar, N. B. R. & Rivarola, V. A., May 1 2017, In : PLoS One. 12, 5, 0177801.

Research output: Contribution to journalArticle

15 Scopus citations

Transcriptional Induction of Periostin by a Sulfatase 2-TGFb1-SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma

Chen, G., Nakamura, I., Dhanasekaran, R., Iguchi, E., Tolosa, E. J., Romecin, P. A., Vera, R. E., Almada, L. L., Miamen, A. G., Chaiteerakij, R., Zhou, M., Asiedu, M. K., Moser, C. D., Han, S., Hu, C., Banini, B. A., Oseini, A. M., Chen, Y., Fang, Y., Yang, D. & 10 others, Shaleh, H. M., Wang, S., Wu, D., Song, T., Lee, J. S., Thorgeirsson, S. S., Chevet, E., Shah, V., Fernandez-Zapico, M. E. & Roberts, L. R., Feb 1 2017, In : Cancer Research. 77, 3, p. 632-645 14 p.

Research output: Contribution to journalArticle

23 Scopus citations
2016

4EBP1/c-MYC/PUMA and NF-kB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells

Yun, S., Vincelette, N. D., Knorr, K. L. B., Almada, L. L., Schneider, P. A., Peterson, K. L., Flatten, K. S., Dai, H., Pratz, K. W., Hess, A. D., Smith, B. D., Karp, J. E., Wahner Hendrickson, A. E., Fernandez-Zapico, M. E. & Kaufmann, S. H., Jun 2 2016, In : Blood. 127, 22, p. 2711-2722 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

Gli transcription factors mediate the oncogenic transformation of prostate basal cells induced by a Kras-androgen receptor axis

Wu, M., Ingram, L., Tolosa, E. J., Vera, R. E., Li, Q., Kim, S., Ma, Y., Spyropoulos, D. D., Beharry, Z., Huang, J., Fernandez-Zapico, M. E. & Cai, H., Dec 2 2016, In : Journal of Biological Chemistry. 291, 49, p. 25749-25760 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Hedgehog signaling overcomes an EZH2-Dependent epigenetic barrier to promote cholangiocyte expansion

Jalan-Sakrikar, N., De Assuncao, T. M., Lu, J., Almada, L. L., Lomberk, G., Fernandez-Zapico, M. E., Urrutia, R. & Huebert, R. C., Dec 1 2016, In : PLoS One. 11, 12, e0168266.

Research output: Contribution to journalArticle

7 Scopus citations

Nuclear factor of activated T cells-dependent downregulation of the transcription factor glioma-associated protein 1 (GLI1) underlies the growth inhibitory properties of arachidonic acid

Comba, A., Almada, L. L., Tolosa, E. J., Iguchi, E., Marks, D. L., Messler, M. V., Silva, R., Fernandez-Barrena, M. G., Enriquez-Hesles, E., Vrabel, A. L., Botta, B., Di Marcotulio, L., Ellenrieder, V., Eynard, A. R., Pasqualini, M. E. & Fernandez-Zapico, M. E., Jan 22 2016, In : Journal of Biological Chemistry. 291, 4, p. 1933-1947 15 p.

Research output: Contribution to journalArticle

7 Scopus citations

Pancreatic cancer microenvironment, to target or not to target?

Carr, R. M. & Fernandez-Zapico, M. E., Feb 1 2016, In : EMBO Molecular Medicine. 8, 2, p. 80-82 3 p.

Research output: Contribution to journalArticle

20 Scopus citations

Poly(ADP-Ribose) polymerases new players in the pathogenesis of exocrine pancreatic diseases

Martínez-Bosch, N., Fernandez-Zapico, M. E., Navarro, P. & Yélamos, J., Feb 1 2016, In : American Journal of Pathology. 186, 2, p. 234-241 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Regulation of GLI underlies a role for BET bromodomains in pancreatic cancer growth and the tumor microenvironment

Huang, Y., Nahar, S., Nakagawa, A., Fernandez-Barrena, M. G., Mertz, J. A., Bryant, B. M., Adams, C. E., Mino-Kenudson, M., Von Alt, K. N., Chang, K., Conery, A. R., Hatton, C., Sims, R. J., Fernandez-Zapico, M. E., Wang, X., Lillemoe, K. D., Castillo, C. F. D., Warshaw, A. L., Thayer, S. P. & Liss, A. S., Aug 15 2016, In : Clinical Cancer Research. 22, 16, p. 4259-4270 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes Kras(G12D)-mediated pancreatic cancer initiation

Loncle, C., Molejon, M. I., Lac, S., Tellechea, J. I., Lomberk, G., Gramatica, L., Fernandez-Zapico, M. E., Dusetti, N., Urrutia, R. & Iovanna, J. L., Jul 14 2016, In : Cell death & disease. 7, p. e2295

Research output: Contribution to journalArticle

11 Scopus citations

The Structure-Specific Recognition Protein 1 Associates with Lens Epithelium-Derived Growth Factor Proteins and Modulates HIV-1 Replication

Lopez, A. P., Kugelman, J. R., Garcia-Rivera, J., Urias, E., Salinas, S. A., Fernandez-Zapico, M. E. & Llano, M., Jul 17 2016, In : Journal of Molecular Biology. 428, 14, p. 2814-2831 18 p.

Research output: Contribution to journalArticle

3 Scopus citations

“Enjoy glass of wine before eating:” a randomized trial to test the orexigenic effects of this advice in advanced cancer patients

Jatoi, A., Qin, R., Satele, D., Dakhil, S., Kumar, P., Johnson, D. B., Thomas, S. P., Stella, P. J., Castillo, J., Li, M. & Fernandez-Zapico, M., Sep 1 2016, In : Supportive Care in Cancer. 24, 9, p. 3739-3746 8 p.

Research output: Contribution to journalArticle

3 Scopus citations
2015

Activation of the transforming growth factor-β/SMAD transcriptional pathway underlies a novel tumor-promoting role of sulfatase 1 in hepatocellular carcinoma

Dhanasekaran, R., Nakamura, I., Hu, C., Chen, G., Oseini, A. M., Seven, E. S., Miamen, A. G., Moser, C. D., Zhou, W., van Kuppevelt, T. H., van Deursen, J. M., Mounajjed, T., Fernandez-Zapico, M. E. & Roberts, L. R., Apr 1 2015, In : Hepatology. 61, 4, p. 1269-1283 15 p.

Research output: Contribution to journalArticle

26 Scopus citations

A preoperative serum signature of CEA+/CA125+/ CA19-9≥1000 U/mL indicates poor outcome to pancreatectomy for pancreatic cancer

Liu, L., Xu, H., Wang, W., Wu, C., Chen, Y., Yang, J., Cen, P., Xu, J., Liu, C., Long, J., Guha, S., Fu, D., Ni, Q., Jatoi, A., Chari, S., McCleary-Wheeler, A. L., Fernandez-Zapico, M. E., Li, M. & Yu, X., May 1 2015, In : International Journal of Cancer. 136, 9, p. 2216-2227 12 p.

Research output: Contribution to journalArticle

57 Scopus citations

Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism

Bednar, F., Schofield, H. K., Collins, M. A., Yan, W., Zhang, Y., Shyam, N., Eberle, J. A., Almada, L. L., Olive, K. P., Bardeesy, N., Fernandez-Zapico, M. E., Nakada, D., Simeone, D. M., Morrison, S. J. & di Magliano, M. P., 2015, In : Carcinogenesis. 36, 7, p. 730-738 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Genome-wide screen identifies a novel p97/CDC-48-dependent pathway regulating ER-stress-induced gene transcription

Marza, E., Taouji, S., Barroso, K., Raymond, A. A., Guignard, L., Bonneu, M., Pallares-Lupon, N., Dupuy, J. W., Fernandez-Zapico, M. E., Rosenbaum, J., Palladino, F., Dupuy, D. & Chevet, E., Mar 1 2015, In : EMBO Reports. 16, 3, p. 332-340 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Identification and characterization of a novel promoter for the human ANO1 gene regulated by the transcription factor signal transducer and activator of transcription 6 (STAT6)

Mazzone, A., Gibbons, S. J., Bernard, C. E., Nowsheen, S., Middha, S., Almada, L. L., Ordog, T., Kendrick, M. L., Lombardo, KM. R., Shen, K. R., Galietta, L. J. V., Fernandez-Zapico, M. E. & Farrugia, G., Jan 1 2015, In : FASEB Journal. 29, 1, p. 152-163 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

Modulation of the IL-6 receptor a underlies GLI2-mediated regulation of Ig secretion in Waldenström macroglobulinemia cells

Jackson, D. A., Smith, T. D., Amarsaikhan, N., Han, W., Neil, M. S., Boi, S. K., Vrabel, A. M., Tolosa, E. J., Almada, L. L., Fernandez-Zapico, M. E. & Elsawa, S. F., Sep 15 2015, In : Journal of Immunology. 195, 6, p. 2908-2916 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Novel roles of the unfolded protein response in the control of tumor development and aggressiveness

Dejeans, N., Barroso, K., Fernandez-Zapico, M. E., Samali, A. & Chevet, E., Aug 1 2015, In : Seminars in Cancer Biology. 33, p. 67-73 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Overexpression of mutant Ptch in rhabdomyosarcomas is associated with promoter hypomethylation and increased Gli1 and H3K4me3 occupancy

Nitzki, F., Tolosa, E. J., Cuvelier, N., Frommhold, A., Salinas-Riester, G., Johnsen, S. A., Fernandez-Zapico, M. E. & Hahn, H., Jan 1 2015, In : Oncotarget. 6, 11, p. 9113-9124 12 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Sonic hedgehog is a chemotactic neural crest cell guide that is perturbed by ethanol exposure

Tolosa, E. J., Fernandez-Zapico, M. E., Battiato, N. L. & Rovasio, R. A., Jun 20 2015, (Accepted/In press) In : European Journal of Cell Biology.

Research output: Contribution to journalArticle

16 Scopus citations

Targeting pancreatic cancer metastasis by inhibition of Vav1, a Driver of Tumor Cell Invasion

Razidlo, G., Magnine, C., Sletten, A. C., Hurley, R. M., Almada, L. L., Fernandez-Zapico, M. E., Ji, B. D. & Mc Niven, M. A., Jul 15 2015, In : Cancer Research. 75, 14, p. 2907-2915 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

The oncogenic transcription factor IRF4 is regulated by a novel CD30/NF-kB positive feedback loop in peripheral T-cell lymphoma

Boddicker, R. L., Kip, N. S., Xing, X., Zeng, Y., Yang, Z. Z., Lee, J. H., Almada, L. L., Elsawa, S. F., Knudson, R. A., Law, M. E., Ketterling, R. P., Cunningham, J. M., Wu, Y., Maurer, M. J., O'Byrne, M. M., Cerhan, J. R., Slager, S. L., Link, B. K., Porcher, J. C., Grote, D. M. & 5 others, Jelinek, D. F., Dogan, A., Ansell, S. M., Fernandez-Zapico, M. E. & Feldman, A. L., Jan 1 2015, In : Blood. 125, 20, p. 3118-3127 10 p.

Research output: Contribution to journalArticle

29 Scopus citations
2014

Back to the drawing board: Re-thinking the role of GLI1 in pancreatic carcinogenesis

Fernandez-Zapico, M., Hogenson, T., Lauth, M. & Pasca diMagliano, M., Oct 8 2014, In : F1000Research. 3

Research output: Contribution to journalArticle

Endoplasmic reticulum stress-activated transcription factor ATF6α requires the disulfide isomerase PDIA5 to modulate chemoresistance

Higa, A., Taouji, S., Lhomond, S., Jensen, D., Fernandez-Zapico, M. E., Simpson, J. C., Pasquet, J. M., Schekman, R. & Chevet, E., May 2014, In : Molecular and cellular biology. 34, 10, p. 1839-1849 11 p.

Research output: Contribution to journalArticle

87 Scopus citations

Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and hedgehog signaling activation

Martínez-Bosch, N., Fern̊andez-Barrena, M. G., Moreno, M., Ortiz-Zapater, E., Munn̊e-Collado, J., Iglesias, M., Andr̊e, S., Gabius, H. J., Hwang, R. F., Coise Poirier, F., Navas, C., Guerra, C., Fern̊andez-Zapico, M. E. & Navarro, P., Jul 1 2014, In : Cancer research. 74, 13, p. 3512-3524 13 p.

Research output: Contribution to journalArticle

61 Scopus citations

Identification of novel non-coding RNA-based negative feedback regulating the expression of the oncogenic transcription factor GLI1

Villegas, V. E., Rahman, M. F. U., Fernandez-Barrena, M. G., Diao, Y., Liapi, E., Sonkoly, E., Ståhle, M., Pivarcsi, A., Annaratone, L., Sapino, A., Ramírez Clavijo, S., Bürglin, T. R., Shimokawa, T., Ramachandran, S., Kapranov, P., Fernandez-Zapico, M. E. & Zaphiropoulos, P. G., Jul 2014, In : Molecular Oncology. 8, 5, p. 912-926 15 p.

Research output: Contribution to journalArticle

16 Scopus citations

Inactivation of the transcription factor GLI1 accelerates pancreatic cancer progression

Mills, L. D., Zhang, L., Marler, R., Svingen, P., Fernandez-Barrena, M. G., Dave, M., Bamlet, W., McWilliams, R. R., Petersen, G. M., Faubion, W. & Fernandez-Zapico, M. E., Jun 6 2014, In : Journal of Biological Chemistry. 289, 23, p. 16516-16525 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Inflammation-Induced NFATc1-STAT3 transcription complex promotes pancreatic cancer initiation by KrasG12D

Baumgart, S., Chen, N. M., Siveke, J. T., König, A., Zhang, J. S., Singh, S. K., Wolf, E., Bartkuhn, M., Esposito, I., Heßmann, E., Reinecke, J., Nikorowitsch, J., Brunner, M., Singh, G., Fernandez-Zapico, M. E., Smyrk, T., Bamlet, W. R., Eilers, M., Neesse, A., Gress, T. M. & 4 others, Billadeau, D. D., Tuveson, D., Urrutia, R. & Ellenrieder, V., Jun 2014, In : Cancer discovery. 4, 6, p. 688-701 14 p.

Research output: Contribution to journalArticle

51 Scopus citations

Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma

Rhim, A. D., Oberstein, P. E., Thomas, D. H., Mirek, E. T., Palermo, C. F., Sastra, S. A., Dekleva, E. N., Saunders, T., Becerra, C. P., Tattersall, I. W., Westphalen, C. B., Kitajewski, J., Fernandez-Barrena, M. G., Fernandez-Zapico, M. E., Iacobuzio-Donahue, C., Olive, K. P. & Stanger, B. Z., Jun 16 2014, In : Cancer cell. 25, 6, p. 735-747 13 p.

Research output: Contribution to journalArticle

781 Scopus citations

The transcription factor GLI1 interacts with SMAD proteins to modulate transforming growth factor β-induced gene expression in a p300/CREB-binding protein-associated factor (PCAF)-dependent manner

Nye, M. D., Almada, L. L., Fernandez-Barrena, M. G., Marks, D. L., Elsawa, S. F., Vrabel, A., Tolosa, E. J., Ellenrieder, V. & Fernandez-Zapico, M. E., May 30 2014, In : Journal of Biological Chemistry. 289, 22, p. 15495-15506 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

The transcription factor GLI1 modulates the inflammatory response during pancreatic tissue remodeling

Mathew, E., Collins, M. A., Fernandez-Barrena, M. G., Holtz, A. M., Yan, W., Hogan, J. O., Tata, Z., Allen, B. L., Fernandez-Zapico, M. E. & Di Magliano, M. P., Oct 3 2014, In : Journal of Biological Chemistry. 289, 40, p. 27727-27743 17 p.

Research output: Contribution to journalArticle

18 Scopus citations
2013

Activation of the transcription factor gli1 by wnt signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration

Nakamura, I., Fernandez-Barrena, M. G., Ortiz-Ruiz, M. C., Almada, L. L., Hu, C., Elsawa, S. F., Mills, L. D., Romecin, P. A., Gulaid, K. H., Moser, C. D., Han, J. J., Vrabel, A., Hanse, E. A., Akogyeram, N. A., Albrecht, J. H., Monga, S. P. S., Sanderson, S. O., Prieto, J., Roberts, L. R. & Fernandez-Zapico, M. E., Jul 19 2013, In : Journal of Biological Chemistry. 288, 29, p. 21389-21398 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth

Zhang, Y., Yang, J., Cui, X., Chen, Y., Zhu, V. F., Hagan, J. P., Wang, H., Yu, X., Hodges, S. E., Fang, J., Chiao, P. J., Logsdon, C. D., Fisher, W. E., Brunicardi, F. C., Chen, C., Yao, Q., Fernandez-Zapico, M. E. & Li, M., Sep 1 2013, In : EMBO Molecular Medicine. 5, 9, p. 1322-1334 13 p.

Research output: Contribution to journalArticle

57 Scopus citations

GLI1 finds a new role in cancer stem cell biology

Fernandez-Zapico, M. E., Apr 1 2013, In : EMBO Molecular Medicine. 5, 4, p. 483-485 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

Krüppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes of the young

Lomberk, G., Grzenda, A., Mathison, A., Escande, C., Zhang, J. S., Calvo, E., Miller, L. J., Iovanna, J., Chini, E. N., Fernandez-Zapico, M. E. & Urrutia, R., Jun 14 2013, In : Journal of Biological Chemistry. 288, 24, p. 17745-17758 14 p.

Research output: Contribution to journalArticle

15 Scopus citations

Loss of the transcription factor GLI1 identifies a signaling network in the tumor microenvironment mediating KRAS oncogene-induced transformation

Mills, L. D., Zhang, Y., Marler, R. J., Herreros-Villanueva, M., Zhang, L., Almada, L. L., Couch, F., Wetmore, C., Di Magliano, M. P. & Fernandez-Zapico, M. E., Apr 26 2013, In : Journal of Biological Chemistry. 288, 17, p. 11786-11794 9 p.

Research output: Contribution to journalArticle

66 Scopus citations