• 12902 Citations
  • 59 Scopus h-Index
1982 …2020

Research output per year

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Research Output

  • 12902 Citations
  • 59 Scopus h-Index
  • 149 Article
  • 5 Chapter
  • 4 Review article
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Article
2020

The anti-viral dynamin family member MxB participates in mitochondrial integrity

Cao, H., Krueger, E. W., Chen, J., Drizyte-Miller, K., Schulz, M. E. & McNiven, M. A., Dec 1 2020, In : Nature communications. 11, 1, 1048.

Research output: Contribution to journalArticle

Open Access
2019
4 Scopus citations

Lipid Droplet Formation and Lipophagy in Fatty Liver Disease

Schulze, R. J. & Mc Niven, M. A., Jan 1 2019, In : Seminars in Liver Disease. 39, 3, p. 283-290 8 p.

Research output: Contribution to journalArticle

Lipid droplet size directs lipolysis and lipophagy catabolism in hepatocytes

Schott, M. B., Weller, S. G., Schulze, R. J., Krueger, E. W., Drizyte-Miller, K., Casey, C. A. & McNiven, M. A., Oct 7 2019, In : The Journal of cell biology. 218, 10, p. 3320-3335 16 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Pancreatic tumor cell metastasis is restricted by MT1-MMP binding protein MTCBP-1

Qiang, L., Cao, H., Chen, J., Weller, S. G., Krueger, E. W., Zhang, L., Razidlo, G. & Mc Niven, M. A., Jan 7 2019, In : The Journal of cell biology. 218, 1, p. 317-332 16 p.

Research output: Contribution to journalArticle

5 Scopus citations

RINT1 Bi-allelic Variations Cause Infantile-Onset Recurrent Acute Liver Failure and Skeletal Abnormalities

Cousin, M. A., Conboy, E., Wang, J. S., Lenz, D., Schwab, T. L., Williams, M., Abraham, R. S., Barnett, S., El-Youssef, M., Graham, R. P., Gutierrez Sanchez, L. H., Hasadsri, L., Hoffmann, G. F., Hull, N. C., Kopajtich, R., Kovacs-Nagy, R., Li, J. Q., Marx-Berger, D., McLin, V., McNiven, M. A. & 9 others, Mounajjed, T., Prokisch, H., Rymen, D., Schulze, R. J., Staufner, C., Yang, Y., Clark, K. J., Lanpher, B. C. & Klee, E. W., Jul 3 2019, In : American journal of human genetics. 105, 1, p. 108-121 14 p.

Research output: Contribution to journalArticle

3 Scopus citations

Small Interfering RNA Screening for the Small GTPase Rab Proteins Identifies Rab5B as a Major Regulator of Hepatitis B Virus Production

Inoue, J., Ninomiya, M., Umetsu, T., Nakamura, T., Kogure, T., Kakazu, E., Iwata, T., Takai, S., Sano, A., Fukuda, M., Watashi, K., Isogawa, M., Tanaka, Y., Shimosegawa, T., Mc Niven, M. A. & Masamune, A., Aug 1 2019, In : Journal of virology. 93, 15

Research output: Contribution to journalArticle

2 Scopus citations
2018

Fasting Inhibits the Recruitment of Kinesin-1 to Lipid Droplets and Stalls Hepatic Triglyceride Secretion

Schulze, R. J. & Mc Niven, M. A., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Interleukin-6 promotes pancreatic cancer cell migration by rapidly activating the small GTPase CDC42

Razidlo, G., Burton, K. M. & Mc Niven, M. A., Jan 1 2018, In : Journal of Biological Chemistry. 293, 28, p. 11143-11153 11 p.

Research output: Contribution to journalArticle

8 Scopus citations
2017

Herpes simplex virus type 1 neuronal infection perturbs golgi apparatus integrity through activation of src tyrosine kinase and Dyn-2 GTPase

Martin, C., Leyton, L., Hott, M., Arancibia, Y., Spichiger, C., Mc Niven, M. A., Court, F. A., Concha, M. I., Burgos, P. V. & Otth, C., Aug 22 2017, In : Frontiers in cellular and infection microbiology. 7, AUG, 371.

Research output: Contribution to journalArticle

7 Scopus citations
26 Scopus citations

β-adrenergic induction of lipolysis in hepatocytes is inhibited by ethanol exposure

Schott, M. B., Rasineni, K., Weller, S. G., Schulze, R. J., Sletten, A. C., Casey, C. A. & Mc Niven, M. A., Jul 14 2017, In : Journal of Biological Chemistry. 292, 28, p. 11815-11828 14 p.

Research output: Contribution to journalArticle

13 Scopus citations
2016

A novel rab10-EHBP1-EHD2 complex essential for the autophagic engulfment of lipid droplets

Li, Z., Schulze, R. J., Weller, S. G., Krueger, E. W., Schott, M. B., Zhang, X., Casey, C. A., Liu, J., Stöckli, J., James, D. E. & Mc Niven, M. A., Dec 1 2016, In : Science advances. 2, 12, 1601470.

Research output: Contribution to journalArticle

37 Scopus citations

Integrated mate-pair and RNA sequencing identifies novel, targetable gene fusions in peripheral T-cell lymphoma

Luchtel, R., Razidlo, G., Dasari, S., Zeng, Y., Hu, G., Knudson, R. A., Greipp, P. T., Davila, J. I., Johnson, S. H., Porcher, J. C., Smadbeck, J., Eckloff, B. W., Billadeau, D. D., Kurtin, P. J., Mc Niven, M. A., Link, B. K., Ansell, S. M., Cerhan, J. R., Asmann, Y., Vasmatzis, G. & 1 others, Feldman, A. L., Sep 1 2016, In : Blood. 128, 9, p. 1234-1245 12 p.

Research output: Contribution to journalArticle

47 Scopus citations

Stromal fibroblasts facilitate cancer cell invasion by a novel invadopodia-independent matrix degradation process

Cao, H., Eppinga, R. D., Razidlo, G., Krueger, E. W., Chen, J., Qiang, L. & Mc Niven, M. A., Mar 3 2016, In : Oncogene. 35, 9, p. 1099-1110 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

The endocytic fate of the transferrin receptor is regulated by c-Abl kinase

Cao, H., Schroeder, B., Chen, J., Schott, M. B. & Mc Niven, M. A., Aug 5 2016, In : Journal of Biological Chemistry. 291, 32, p. 16424-16437 14 p.

Research output: Contribution to journalArticle

8 Scopus citations
2015

HBV secretion is regulated through the activation of endocytic and autophagic compartments mediated by Rab7 stimulation

Inoue, J., Krueger, E. W., Chen, J., Cao, H., Ninomiya, M. & Mc Niven, M. A., 2015, In : Journal of Cell Science. 128, 9, p. 1696-1706 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Hdac3 Deficiency Increases Marrow Adiposity and Induces Lipid Storage and Glucocorticoid Metabolism in Osteochondroprogenitor Cells

McGee-Lawrence, M. E., Carpio, L. R., Schulze, R. J., Pierce, J. L., Mc Niven, M. A., Farr, J., Khosla, S., Oursler, M. J. & Westendorf, J. J., 2015, (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Contribution to journalArticle

27 Scopus citations

Targeting pancreatic cancer metastasis by inhibition of Vav1, a Driver of Tumor Cell Invasion

Razidlo, G., Magnine, C., Sletten, A. C., Hurley, R. M., Almada, L. L., Fernandez-Zapico, M. E., Ji, B. D. & Mc Niven, M. A., Jul 15 2015, In : Cancer Research. 75, 14, p. 2907-2915 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

The small GTPase Rab7 as a central regulator of hepatocellular lipophagy

Schroeder, B., Schulze, R. J., Weller, S. G., Sletten, A. C., Casey, C. A. & Mc Niven, M. A., Jun 1 2015, In : Hepatology. 61, 6, p. 1896-1907 12 p.

Research output: Contribution to journalArticle

87 Scopus citations
2014
6 Scopus citations

Importance of endocytic pathways in liver function and disease

Schroeder, B. & Mc Niven, M. A., Oct 1 2014, In : Comprehensive Physiology. 4, 4, p. 1403-1417 15 p.

Research output: Contribution to journalArticle

9 Scopus citations

Preclinical evaluation of the supercritical extract of azadirachta indica (neem) leaves in vitro and in vivo on inhibition of prostate cancer tumor growth

Wu, Q., Kohli, M., Bergen, H. R. B. III., Cheville, J. C., Karnes, R. J., Cao, H., Young, C. Y. F., Tindall, D. J., Mc Niven, M. A. & Donkena, K. V., 2014, In : Molecular Cancer Therapeutics. 13, 5, p. 1067-1077 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Rab GTPases Associate with Isolated Lipid Droplets (LDs) and Show Altered Content After Ethanol Administration: Potential Role in Alcohol-Impaired LD Metabolism

Rasineni, K., Mcvicker, B. L., Tuma, D. J., Mc Niven, M. A. & Casey, C. A., Feb 2014, In : Alcoholism: Clinical and Experimental Research. 38, 2, p. 327-335 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Vav1 as a central regulator of invadopodia assembly

Razidlo, G., Schroeder, B., Chen, J., Billadeau, D. D. & Mc Niven, M. A., Jan 6 2014, In : Current Biology. 24, 1, p. 86-93 8 p.

Research output: Contribution to journalArticle

33 Scopus citations
2013

Breaking away: Matrix remodeling from the leading edge

Mc Niven, M. A., Jan 2013, In : Trends in Cell Biology. 23, 1, p. 16-21 6 p.

Research output: Contribution to journalArticle

45 Scopus citations

Dynamin 2 Potentiates Invasive Migration of Pancreatic Tumor Cells through Stabilization of the Rac1 GEF Vav1

Razidlo, G., Wang, Y., Chen, J., Krueger, E. W., Billadeau, D. D. & Mc Niven, M. A., Mar 25 2013, In : Developmental Cell. 24, 6, p. 573-585 13 p.

Research output: Contribution to journalArticle

37 Scopus citations
2012

CIN85 phosphorylation is essential for EGFR ubiquitination and sorting into multivesicular bodies

Schroeder, B., Srivatsan, S., Shaw, A., Billadeau, D. D. & Mc Niven, M. A., Sep 15 2012, In : Molecular Biology of the Cell. 23, 18, p. 3602-3611 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Increased expression of the large GTPase dynamin 2 potentiates metastatic migration and invasion of pancreatic ductal carcinoma

Eppinga, R. D., Krueger, E. W., Weller, S. G., Zhang, L., Cao, H. & Mc Niven, M. A., Mar 8 2012, In : Oncogene. 31, 10, p. 1228-1241 14 p.

Research output: Contribution to journalArticle

31 Scopus citations

Invasive matrix degradation at focal adhesions occurs via protease recruitment by a FAK-p130Cas complex

Wang, Y. & Mc Niven, M. A., Feb 6 2012, In : Journal of Cell Biology. 196, 3, p. 375-385 11 p.

Research output: Contribution to journalArticle

133 Scopus citations
2011

Calcineurin selectively docks with the dynamin Ixb splice variant to regulate activity-dependent bulk endocytosis

Xue, J., Graham, M. E., Novelle, A. E., Sue, N., Gray, N., Mc Niven, M. A., Smillie, K. J., Cousin, M. A. & Robinson, P. J., Sep 2 2011, In : Journal of Biological Chemistry. 286, 35, p. 30295-30303 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Growth cone morphology and spreading are regulated by a dynamin-cortactin complex at point contacts in hippocampal neurons

Kurklinsky, S., Chen, J. & Mc Niven, M. A., Apr 2011, In : Journal of Neurochemistry. 117, 1, p. 48-60 13 p.

Research output: Contribution to journalArticle

27 Scopus citations

Hepatocytes internalize trophic receptors at large endocytic "Hot Spots"

Cao, H., Krueger, E. W. & Mc Niven, M. A., Nov 2011, In : Hepatology. 54, 5, p. 1819-1829 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Recycling of the epidermal growth factor receptor is mediated by a novel form of the clathrin adaptor protein Eps15

Chi, S., Cao, H., Wang, Y. & Mc Niven, M. A., Oct 7 2011, In : Journal of Biological Chemistry. 286, 40, p. 35196-35208 13 p.

Research output: Contribution to journalArticle

26 Scopus citations
2010

A Dyn2-CIN85 complex mediates degradative traffic of the EGFR by regulation of late endosomal budding

Schroeder, B., Weller, S. G., Chen, J., Billadeau, D. D. & Mc Niven, M. A., Sep 2010, In : EMBO Journal. 29, 18, p. 3039-3053 15 p.

Research output: Contribution to journalArticle

38 Scopus citations
30 Scopus citations

Nanoconjugation modulates the trafficking and mechanism of antibody induced receptor endocytosis

Bhattacharyya, S., Bhattacharya, R., Curley, S., Mc Niven, M. A. & Mukherjee, P., Aug 17 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 33, p. 14541-14546 6 p.

Research output: Contribution to journalArticle

102 Scopus citations

Src kinase regulates the integrity and function of the Golgi apparatus via activation of dynamin 2

Weller, S. G., Capitani, M., Cao, H., Micaroni, M., Luini, A., Sallese, M. & Mc Niven, M. A., Mar 30 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 13, p. 5863-5868 6 p.

Research output: Contribution to journalArticle

65 Scopus citations

Src-mediated phosphorylation of dynamin and cortactin regulates the "constitutive" endocytosis of transferrin

Cao, H., Chen, J., Krueger, E. W. & Mc Niven, M. A., Feb 2010, In : Molecular and Cellular Biology. 30, 3, p. 781-792 12 p.

Research output: Contribution to journalArticle

73 Scopus citations
2009

A stimulus needed for the study of membrane traffic in hepatocytes

Mc Niven, M. A., Wolkoff, A. W. & Hubbard, A., 2009, In : Hepatology. 50, 2, p. 345-348 4 p.

Research output: Contribution to journalArticle

7 Scopus citations
46 Scopus citations

Death Receptor 5 Internalization Is Required for Lysosomal Permeabilization by TRAIL in Malignant Liver Cell Lines

Akazawa, Y., Mott, J. L., Bronk, S. F., Werneburg, N. W., Kahraman, A., Guicciardi, M. E., Meng, X. W., Kohno, S., Shah, V., Kaufmann, S. H., Mc Niven, M. A. & Gores, G. J., Jun 2009, In : Gastroenterology. 136, 7

Research output: Contribution to journalArticle

49 Scopus citations
2008

Distinct phospho-forms of cortactin differentially regulate actin polymerization and focal adhesions

Kruchten, A. E., Krueger, E. W., Wang, Y. & Mc Niven, M. A., Nov 2008, In : American Journal of Physiology - Cell Physiology. 295, 5

Research output: Contribution to journalArticle

42 Scopus citations

Eps15 mediates vesicle trafficking from the trans-Golgi network via an interaction with the clathrin adaptor AP-1

Chi, S., Cao, H., Chen, J. & Mc Niven, M. A., Aug 2008, In : Molecular Biology of the Cell. 19, 8, p. 3564-3575 12 p.

Research output: Contribution to journalArticle

31 Scopus citations
29 Scopus citations