• 17340 Citations
  • 69 Scopus h-Index
1991 …2019
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Research Output 1991 2019

  • 17340 Citations
  • 69 Scopus h-Index
  • 302 Article
  • 3 Review article
  • 2 Comment/debate
  • 1 Chapter
2019

A phenome-wide association study to discover pleiotropic effects of PCSK9, APOB, and LDLR

Safarova, M. S., Satterfield, B. A., Fan, X., Austin, E. E., Ye, Z., Bastarache, L., Zheng, N., Ritchie, M. D., Borthwick, K. M., Williams, M. S., Larson, E. B., Scrol, A., Jarvik, G. P., Crosslin, D. R., Leppig, K., Rasmussen-Torvik, L. J., Pendergrass, S. A., Sturm, A. C., Namjou, B., Shah, A. S. & 12 others, Carroll, R. J., Chung, W. K., Wei, W. Q., Feng, Q. P., Stein, C. M., Roden, D. M., Manolio, T. A., Schaid, D. J., Denny, J. C., Hebbring, S. J., De Andrade, M. & Kullo, I. J., Dec 1 2019, In : npj Genomic Medicine. 4, 1, 3.

Research output: Contribution to journalArticle

Open Access
Electronic Health Records
Precision Medicine
Genetic Models
Myopia
Linkage Disequilibrium
10 Citations (Scopus)

Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection

DISCO Consortium & CARDIoGRAMPlusC4D Study Group, Jan 8 2019, In : Journal of the American College of Cardiology. 73, 1, p. 58-66 9 p.

Research output: Contribution to journalArticle

Genetic Loci
Endothelin-1
Fibromuscular Dysplasia
Odds Ratio
Confidence Intervals
2 Citations (Scopus)

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

Kraja, A. T., Liu, C., Fetterman, J. L., Graff, M., Have, C. T., Gu, C., Yanek, L. R., Feitosa, M. F., Arking, D. E., Chasman, D. I., Young, K., Ligthart, S., Hill, W. D., Weiss, S., Luan, J., Giulianini, F., Li-Gao, R., Hartwig, F. P., Lin, S. J., Wang, L. & 132 others, Richardson, T. G., Yao, J., Fernandez, E. P., Ghanbari, M., Wojczynski, M. K., Lee, W. J., Argos, M., Armasu, S. M., Barve, R. A., Ryan, K. A., An, P., Baranski, T. J., Bielinski, S. J., Bowden, D. W., Broeckel, U., Christensen, K., Chu, A. Y., Corley, J., Cox, S. R., Uitterlinden, A. G., Rivadeneira, F., Cropp, C. D., Daw, E. W., van Heemst, D., de las Fuentes, L., Gao, H., Tzoulaki, I., Ahluwalia, T. S., de Mutsert, R., Emery, L. S., Erzurumluoglu, A. M., Perry, J. A., Fu, M., Forouhi, N. G., Gu, Z., Hai, Y., Harris, S. E., Hemani, G., Hunt, S. C., Irvin, M. R., Jonsson, A. E., Justice, A. E., Kerrison, N. D., Larson, N., Lin, K. H., Love-Gregory, L. D., Mathias, R. A., Lee, J. H., Nauck, M., Noordam, R., Ong, K. K., Pankow, J., Patki, A., Pattie, A., Petersmann, A., Qi, Q., Ribel-Madsen, R., Rohde, R., Sandow, K., Schnurr, T. M., Sofer, T., Starr, J. M., Taylor, A. M., Teumer, A., Timpson, N. J., de Haan, H. G., Wang, Y., Weeke, P. E., Williams, C., Wu, H., Yang, W., Zeng, D., Witte, D. R., Weir, B. S., Wareham, N. J., Vestergaard, H., Turner, S. T., Torp-Pedersen, C., Stergiakouli, E., Sheu, W. H. H., Rosendaal, F. R., Ikram, M. A., Franco, O. H., Ridker, P. M., Perls, T. T., Pedersen, O., Nohr, E. A., Newman, A. B., Linneberg, A., Langenberg, C., Kilpeläinen, T. O., Kardia, S. L. R., Jørgensen, M. E., Jørgensen, T., Sørensen, T. I. A., Homuth, G., Hansen, T., Goodarzi, M. O., Deary, I. J., Christensen, C., Chen, Y. D. I., Chakravarti, A., Brandslund, I., Bonnelykke, K., Taylor, K. D., Wilson, J. G., Rodriguez, S., Davies, G., Horta, B. L., Thyagarajan, B., Rao, D. C., Grarup, N., Davila-Roman, V. G., Hudson, G., Guo, X., Arnett, D. K., Hayward, C., Vaidya, D., Mook-Kanamori, D. O., Tiwari, H. K., Levy, D., Loos, R. J. F., Dehghan, A., Elliott, P., Malik, A. N., Scott, R. A., Becker, D. M., De Andrade, M., Province, M. A., Meigs, J. B., Rotter, J. I. & North, K. E., Jan 3 2019, In : American Journal of Human Genetics. 104, 1, p. 112-138 27 p.

Research output: Contribution to journalArticle

Mitochondrial Genes
Mitochondria
Mitochondrial DNA
Genes
Waist-Hip Ratio
1 Citation (Scopus)

Immune Cell Infiltration May Be a Key Determinant of Long-Term Survival in Small Cell Lung Cancer

Muppa, P., Parrilha Terra, S. B. S., Sharma, A., Mansfield, A., Aubry, M. C., Bhinge, K., Asiedu, M. K., De Andrade, M., Janaki, N., Murphy, S. J., Nasir, A., Van Keulen, V., Vasmatzis, G., Wigle, D. A., Yang, P., Yi, E. S., Peikert, T. D. & Kosari, F., Jul 1 2019, In : Journal of Thoracic Oncology. 14, 7, p. 1286-1295 10 p.

Research output: Contribution to journalArticle

Open Access
Small Cell Lung Carcinoma
Tumor Microenvironment
Survival Rate
Survivors
Survival

Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region

Hung, R. J., Spitz, M. R., Houlston, R. S., Schwartz, A. G., Field, J. K., Ying, J., Li, Y., Han, Y., Ji, X., Chen, W., Wu, X., Gorlov, I. P., Na, J., De Andrade, M., Liu, G., Brhane, Y., Diao, N., Wenzlaff, A., Davies, M. P. A., Liloglou, T. & 46 others, Timofeeva, M., Muley, T., Rennert, H., Saliba, W., Ryan, B. M., Bowman, E., Barros-Dios, J. M., Pérez-Ríos, M., Morgenstern, H., Zienolddiny, S., Skaug, V., Ugolini, D., Bonassi, S., van der Heijden, E. H. F. M., Tardon, A., Bojesen, S. E., Landi, M. T., Johansson, M., Bickeböller, H., Arnold, S., Le Marchand, L., Melander, O., Andrew, A., Grankvist, K., Caporaso, N., Teare, M. D., Schabath, M. B., Aldrich, M. C., Kiemeney, L. A., Wichmann, H. E., Lazarus, P., Mayordomo, J., Neri, M., Haugen, A., Zhang, Z. F., Ruano-Raviña, A., Brenner, H., Harris, C. C., Orlow, I., Rennert, G., Risch, A., Brennan, P., Christiani, D. C., Amos, C. I., Yang, P. & Gorlova, O. Y., Jan 1 2019, In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

Open Access
Lung Neoplasms
Genome-Wide Association Study
Odds Ratio
Confidence Intervals
Gene-Environment Interaction
2018

Age-related DNA methylation and hemostatic factors

De Andrade, M., Oct 25 2018, In : Blood. 132, 17, 1 p.

Research output: Contribution to journalReview article

Hemostatics
DNA Methylation
Epigenomics
Blood
Aging of materials
Venous Thromboembolism
Medical Genetics
Random Allocation
Names
Obesity
12 Citations (Scopus)

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

NHLBI TOPMed Lipids Working Group, Dec 1 2018, In : Nature Communications. 9, 1, 3391.

Research output: Contribution to journalArticle

sequencing
genome
cholesterol
lipoproteins
blood
8 Citations (Scopus)

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

Zekavat, S. M., Ruotsalainen, S., Handsaker, R. E., Alver, M., Bloom, J., Poterba, T., Seed, C., Ernst, J., Chaffin, M., Engreitz, J., Peloso, G. M., Manichaikul, A., Yang, C., Ryan, K. A., Fu, M., Johnson, W. C., Tsai, M., Budoff, M., Ramachandran, V. S., Cupples, L. A. & 323 others, Rotter, J. I., Rich, S. S., Post, W., Mitchell, B. D., Correa, A., Metspalu, A., Wilson, J. G., Salomaa, V., Kellis, M., Daly, M. J., Neale, B. M., McCarroll, S., Surakka, I., Esko, T., Ganna, A., Ripatti, S., Kathiresan, S., Natarajan, P., Abe, N., Abecasis, G., Albert, C., Allred, N. P., Almasy, L., Alonso, A., Ament, S., Anderson, P., Anugu, P., Applebaum-Bowden, D., Arking, D., Arnett, D. K., Ashley-Koch, A., Aslibekyan, S., Assimes, T., Auer, P., Avramopoulos, D., Barnard, J., Barnes, K., Barr, R. G., Barron-Casella, E., Beaty, T., Becker, D., Becker, L., Beer, R., Begum, F., Beitelshees, A., Benjamin, E., Bezerra, M., Bielak, L., Bis, J., Blackwell, T., Blangero, J., Boerwinkle, E., Borecki, I., Bowler, R., Brody, J., Broeckel, U., Broome, J., Bunting, K., Burchard, E., Cardwell, J., Carty, C., Casaburi, R., Casella, J., Chang, C., Chasman, D., Chavan, S., Chen, B. J., Chen, W. M., Chen, Y. D. I., Cho, M., Choi, S. H., Chuang, L. M., Chung, M., Cornell, E., Crandall, C., Crapo, J., Curran, J., Curtis, J., Custer, B., Damcott, C., Darbar, D., Das, S., David, S., Davis, C., Daya, M., De Andrade, M., Debaun, M., Deka, R., Demeo, D., Devine, S., Do, R., Duan, Q., Duggirala, R., Durda, P., Dutcher, S., Eaton, C., Ekunwe, L., Ellinor, P., Emery, L., Farber, C., Farnam, L., Fingerlin, T., Flickinger, M., Fornage, M., Franceschini, N., Fullerton, S. M., Fulton, L., Gabriel, S., Gan, W., Gao, Y., Gass, M., Gelb, B., Geng, X., Germer, S., Gignoux, C., Gladwin, M., Glahn, D., Gogarten, S., Gong, D. W., Goring, H., Gu, C. C., Guan, Y., Guo, X., Haessler, J., Hall, M., Harris, D., Hawley, N., He, J., Heavner, B., Heckbert, S., Hernandez, R., Herrington, D., Hersh, C., Hidalgo, B., Hixson, J., Hokanson, J., Hong, E., Hoth, K., Hsiung, C., Huston, H., Hwu, C. M., Irvin, M. R., Jackson, R., Jain, D., Jaquish, C., Jhun, M. A., Johnsen, J., Johnson, A., Johnston, R., Jones, K., Kang, H. M., Kaplan, R., Kardia, S., Kaufman, L., Kelly, S., Kenny, E., Kessler, M., Khan, A., Kinney, G., Konkle, B., Kooperberg, C., Kramer, H., Krauter, S., Lange, C., Lange, E., Lange, L., Laurie, C., Laurie, C., Leboff, M., Lee, S. S., Lee, W. J., Lefaive, J., Levine, D., Levy, D., Lewis, J., Li, Y., Lin, H., Lin, K. H., Liu, S., Liu, Y., Loos, R., Lubitz, S., Lunetta, K., Luo, J., Mahaney, M., Make, B., Manson, J. A., Margolin, L., Martin, L., Mathai, S., Mathias, R., McArdle, P., McDonald, M. L., McFarland, S., McGarvey, S., Mei, H., Meyers, D. A., Mikulla, J., Min, N., Minear, M., Minster, R. L., Montasser, M. E., Musani, S., Mwasongwe, S., Mychaleckyj, J. C., Nadkarni, G., Naik, R., Nekhai, S., Nickerson, D., North, K., O'connell, J., O'connor, T., Ochs-Balcom, H., Pankow, J., Papanicolaou, G., Parker, M., Parsa, A., Penchev, S., Peralta, J. M., Perez, M., Perry, J., Peters, U., Peyser, P., Phillips, L., Phillips, S., Pollin, T., Becker, J. P., Boorgula, M. P., Preuss, M., Prokopenko, D., Psaty, B., Qasba, P., Qiao, D., Qin, Z., Rafaels, N., Raffield, L., Rao, D. C., Rasmussen-Torvik, L., Ratan, A., Redline, S., Reed, R., Regan, E., Reiner, A., Rice, K., Roden, D., Roselli, C., Ruczinski, I., Russell, P., Ruuska, S., Sakornsakolpat, P., Salimi, S., Salzberg, S., Sandow, K., Sankaran, V., Scheller, C., Schmidt, E., Schwander, K., Schwartz, D., Sciurba, F., Seidman, C., Sheehan, V., Shetty, A., Shetty, A., Sheu, W. H. H., Shoemaker, M. B., Silver, B., Silverman, E., Smith, J., Smith, J., Smith, N., Smith, T., Smoller, S., Snively, B., Sofer, T., Sotoodehnia, N., Stilp, A., Streeten, E., Sung, Y. J., Sylvia, J., Szpiro, A., Sztalryd, C., Taliun, D., Tang, H., Taub, M., Taylor, K., Taylor, S., Telen, M., Thornton, T. A., Tinker, L., Tirschwell, D., Tiwari, H., Tracy, R., Vaidya, D., Vandehaar, P., Vrieze, S., Walker, T., Wallace, R., Walts, A., Wan, E., Wang, F. F., Watson, K., Weeks, D. E., Weir, B., Weiss, S., Weng, L. C., Willer, C., Williams, K., Williams, L. K., Wilson, C., Wong, Q., Xu, H., Yanek, L., Yang, I., Yang, R., Zaghloul, N., Zhang, Y., Zhao, S. X., Zhao, W., Zheng, X., Zhi, D., Zhou, X., Zody, M. & Zoellner, S., Dec 1 2018, In : Nature Communications. 9, 1, 2606.

Research output: Contribution to journalArticle

lipoproteins
Lipoprotein(a)
genome
Cardiovascular Diseases
Genes
document markup languages
lipoproteins
Lipoprotein(a)
HTML
genome
1 Citation (Scopus)

GAW20: Methods and strategies for the new frontiers of epigenetics and pharmacogenomics

Tintle, N. L., Fardo, D. W., De Andrade, M., Aslibekyan, S., Bailey, J. N., Bermejo, J. L., Cantor, R. M., Ghosh, S., Melton, P., Wang, X., MacCluer, J. W. & Almasy, L., Sep 17 2018, In : BMC Proceedings. 12, 26.

Research output: Contribution to journalArticle

Pharmacogenetics
DNA Methylation
Epigenomics
Nucleotides
Fenofibrate
3 Citations (Scopus)

Genome-wide association study of familial lung cancer

Byun, J., Schwartz, A. G., Lusk, C., Wenzlaff, A. S., De Andrade, M., Mandal, D., Gaba, C., Yang, P., You, M., Kupert, E. Y., Anderson, M. W., Han, Y., Li, Y., Qian, D., Stilp, A., Laurie, C., Nelson, S., Zheng, W., Hung, R. J., Gaborieau, V. & 11 others, Mckay, J., Brennan, P., Caporaso, N. E., Landi, M. T., Wu, X., McLaughlin, J. R., Brhane, Y., Bossé, Y., Pinney, S. M., Bailey-Wilson, J. E. & Amos, C. I., Jan 1 2018, In : Carcinogenesis. 39, 9, p. 1135-1140 6 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Lung Neoplasms
Chromosomes
Genome
Squamous Cell Carcinoma
1 Citation (Scopus)

Long-term risk of depressive and anxiety symptoms after early bilateral oophorectomy

Rocca, W. A., Grossardt, B. R., Geda, Y. E., Gostout, B. S., Bower, J. H., Maraganore, D. M., De Andrade, M. & Melton, L. J., Nov 1 2018, In : Menopause (New York, N.Y.). 25, 11, p. 1275-1285 11 p.

Research output: Contribution to journalArticle

Ovariectomy
Anxiety
Depression
Menopause
Interviews

Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer

Liu, Y., Lusk, C. M., Cho, M. H., Silverman, E. K., Qiao, D., Zhang, R., Scheurer, M. E., Kheradmand, F., Wheeler, D. A., Tsavachidis, S., Armstrong, G., Zhu, D., Wistuba, I. I., Chow, C. W. B., Behrens, C., Pikielny, C. W., Neslund-Dudas, C., Pinney, S. M., Anderson, M., Kupert, E. & 26 others, Bailey-Wilson, J., Gaba, C., Mandal, D., You, M., De Andrade, M., Yang, P., Field, J. K., Liloglou, T., Davies, M., Lissowska, J., Swiatkowska, B., Zaridze, D., Mukeriya, A., Janout, V., Holcatova, I., Mates, D., Milosavljevic, S., Scelo, G., Brennan, P., McKay, J., Liu, G., Hung, R. J., Christiani, D. C., Schwartz, A. G., Amos, C. I. & Spitz, M. R., Oct 1 2018, In : Journal of Thoracic Oncology. 13, 10, p. 1483-1495 13 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Genes
Lymphotoxin-beta
Confidence Intervals
Exome
1 Citation (Scopus)

SLCO1B1 genetic variation and hormone therapy in menopausal women

Moyer, A. M., De Andrade, M., Faubion, S. S., Kapoor, E., Dudenkov, T., Weinshilboum, R. M. & Miller, V. M., Aug 1 2018, In : Menopause (New York, N.Y.). 25, 8, p. 877-882 6 p.

Research output: Contribution to journalArticle

Hormones
Sweat
Estrogens
Genotype
Therapeutics
2 Citations (Scopus)

Targeted sequencing to identify novel genetic risk factors for deep vein thrombosis: a study of 734 genes

the INVENT consortium, Jan 1 2018, (Accepted/In press) In : Journal of Thrombosis and Haemostasis.

Research output: Contribution to journalArticle

Venous Thrombosis
Genes
Hemostasis
Thrombophilia
Gene Frequency

The challenge of detecting genotype-by-methylation interaction: GAW20 01 Mathematical Sciences 0104 Statistics

De Andrade, M., Warwick Daw, E., Kraja, A. T., Fisher, V., Wang, L., Hu, K., Li, J., Romanescu, R., Veenstra, J., Sun, R., Weng, H. & Zhou, W., Sep 17 2018, In : BMC Genetics. 19, 81.

Research output: Contribution to journalArticle

Methylation
Single Nucleotide Polymorphism
Cytosine
Guanine
Genotype
3 Citations (Scopus)
Electronic Health Records
Herpes Zoster
Genomics
Medical Records
Genotype
2017
2 Citations (Scopus)

An efficient test for gene-environment interaction in generalized linear mixed models with family data

Mazo Lopera, M. A., Coombes, B. J. & De Andrade, M., Sep 27 2017, In : International Journal of Environmental Research and Public Health. 14, 10, 1134.

Research output: Contribution to journalArticle

Gene-Environment Interaction
Linear Models
Genes
PPAR gamma
Linkage Disequilibrium
9 Citations (Scopus)

Assessing the causal relationship between obesity and venous thromboembolism through a Mendelian Randomization study

Lindström, S., Germain, M., Crous-Bou, M., Smith, E. N., Morange, P. E., van Hylckama Vlieg, A., de Haan, H. G., Chasman, D., Ridker, P., Brody, J., De Andrade, M., Heit, J. A., Tang, W., DeVivo, I., Grodstein, F., Smith, N. L., Tregouet, D., Kabrhel, C. & for the INVENT Consortium, T. INVENT. C., Jul 1 2017, In : Human Genetics. 136, 7, p. 897-902 6 p.

Research output: Contribution to journalArticle

Venous Thromboembolism
Random Allocation
Obesity
Body Mass Index
Single Nucleotide Polymorphism
26 Citations (Scopus)

Causal effect of plasminogen activator inhibitor type 1 on coronary heart disease

CHARGE Consortium Hemostatic Factor Working Group, ICBP Consortium & CHARGE Consortium Subclinical Working Group, Jun 1 2017, In : Journal of the American Heart Association. 6, 6, e004918.

Research output: Contribution to journalArticle

Plasminogen Activator Inhibitor 1
Coronary Disease
Odds Ratio
Mendelian Randomization Analysis
Genome-Wide Association Study
3 Citations (Scopus)

EGFR mediates activation of RET in lung adenocarcinoma with neuroendocrine differentiation characterized by ASCL1 expression

Bhinge, K., Yang, L., Terra, S., Nasir, A., Muppa, P., Aubry, M. C., Yi, J., Janaki, N., Kovtun, I. V., Murphy, S. J., Halling, G., Rahi, H., Mansfield, A., De Andrade, M., Yang, P., Vasmatzis, G., Peikert, T. D. & Kosari, F., 2017, In : Oncotarget. 8, 16, p. 27155-27165 11 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Adenocarcinoma
Epidermal Growth Factor
Protein Isoforms
Phosphorylation
1 Citation (Scopus)

Elevated Levels of Adhesion Proteins Are Associated with Low Ankle-Brachial Index: Multi-Ethnic Study of Atherosclerosis

Berardi, C., Wassel, C. L., Decker, P. A., Larson, N., Kirsch, P. S., De Andrade, M., Tsai, M. Y., Pankow, J. S., Sale, M. M., Sicotte, H., Tang, W., Hanson, N. Q., McDermott, M. M., Criqui, M. H., Allison, M. A. & Bielinski, S. J., Apr 1 2017, In : Angiology. 68, 4, p. 322-329 8 p.

Research output: Contribution to journalArticle

Ankle Brachial Index
Atherosclerosis
Proteins
Peripheral Arterial Disease
Secretory Leukocyte Peptidase Inhibitor
7 Citations (Scopus)

Familial lung cancer: A brief history from the earliestwork to the most recent studies

Musolf, A. M., Simpson, C. L., De Andrade, M., Mandal, D., Gaba, C., Yang, P., Li, Y., You, M., Kupert, E. Y., Anderson, M. W., Schwartz, A. G., Pinney, S. M., Amos, C. I. & Bailey-Wilson, J. E., Jan 17 2017, In : Genes. 8, 1, 36.

Research output: Contribution to journalReview article

Lung Neoplasms
History
Alleles
Penetrance
Germ-Line Mutation
9 Citations (Scopus)

Genome-wide study of resistant hypertension identified from electronic health records

Dumitrescu, L., Ritchie, M. D., Denny, J. C., Rouby, N. M. E., McDonough, C. W., Bradford, Y., Ramirez, A. H., Bielinski, S. J., Basford, M. A., Chai, H. S., Peissig, P., Carrell, D., Pathak, J., Rasmussen, L. V., Wang, X., Pacheco, J. A., Kho, A. N., Hayes, M. G., Matsumoto, M., Smith, M. E. & 15 others, Li, R., Cooper-DeHoff, R. M., Kullo, I. J., Chute, C. G., Chisholm, R. L., Jarvik, G. P., Larson, E. B., Carey, D., McCarty, C. A., Williams, M. S., Roden, D. M., Bottinger, E., Johnson, J. A., De Andrade, M. & Crawford, D. C., Feb 1 2017, In : PLoS One. 12, 2, e0171745.

Research output: Contribution to journalArticle

Electronic Health Records
hypertension
electronics
Genes
Blood pressure
3 Citations (Scopus)

Hepatocyte growth factor demonstrates racial heterogeneity as a biomarker for coronary heart disease

Bielinski, S. J., Berardi, C., Decker, P. A., Larson, N., Bell, E. J., Pankow, J. S., Sale, M. M., Tang, W., Hanson, N. Q., Wassel, C. L., De Andrade, M., Budoff, M. J., Polak, J. F., Sicotte, H. & Tsai, M. Y., Aug 1 2017, In : Heart. 103, 15, p. 1185-1193 9 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Coronary Disease
Biomarkers
Hispanic Americans
African Americans
1 Citation (Scopus)

Identification of genetic interaction with risk factors using a time-to-event model

De Andrade, M., Armasu, S. M., McCauley, B. M., Petterson, T. M. & Heit, J. A., Oct 15 2017, In : International Journal of Environmental Research and Public Health. 14, 10, 1228.

Research output: Contribution to journalArticle

Venous Thromboembolism
Postpartum Period
Single Nucleotide Polymorphism
Pregnancy
Chromosomes, Human, Pair 9
4 Citations (Scopus)

Identification of unique venous thromboembolism-susceptibility variants in African-Americans

Heit, J. A., Armasu, S. M., McCauley, B. M., Kullo, I. J., Sicotte, H., Pathak, J., Chute, C. G., Gottesman, O., Bottinger, E. P., Denny, J. C., Roden, D. M., Li, R., Ritchie, M. D. & De Andrade, M., 2017, In : Thrombosis and Haemostasis. 117, 4, p. 758-768 11 p.

Research output: Contribution to journalArticle

Venous Thromboembolism
African Americans
Single Nucleotide Polymorphism
Electronic Health Records
Gene Expression
28 Citations (Scopus)

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci

Jones, G. T., Tromp, G., Kuivaniemi, H., Gretarsdottir, S., Baas, A. F., Giusti, B., Strauss, E., Van'T Hof, F. N. G., Webb, T. R., Erdman, R., Ritchie, M. D., Elmore, J. R., Verma, A., Pendergrass, S., Kullo, I. J., Ye, Z., Peissig, P. L., Gottesman, O., Verma, S. S., Malinowski, J. & 97 others, Rasmussen-Torvik, L. J., Borthwick, K. M., Smelser, DI. T., Crosslin, D. R., De Andrade, M., Ryer, E. J., McCarty, C. A., Böttinger, E. P., Pacheco, J. A., Crawford, D. C., Carrell, D. S., Gerhard, G. S., Franklin, D. P., Carey, D. J., Phillips, V. L., Williams, M. J. A., Wei, W., Blair, R., Hill, A. A., Vasudevan, T. M., Lewis, D. R., Thomson, I. A., Krysa, J., Hill, G. B., Roake, J., Merriman, T. R., Oszkinis, G., Galora, S., Saracini, C., Abbate, R., Pulli, R., Pratesi, C., Saratzis, A., Verissimo, A. R., Bumpstead, S., Badger, S. A., Clough, R. E., Cockerill, G., Hafez, H., Scott, D. J. A., Futers, T. S., Romaine, S. P. R., Bridge, K., Griffin, K. J., Bailey, M. A., Smith, A., Thompson, M. M., Van Bockxmeer, F. M., Matthiasson, S. E., Thorleifsson, G., Thorsteinsdottir, U., Blankensteijn, J. D., Teijink, J. A. W., Wijmenga, C., De Graaf, J., Kiemeney, L. A., Lindholt, J. S., Hughes, A., Bradley, D. T., Stirrups, K., Golledge, J., Norman, P. E., Powell, J. T., Humphries, S. E., Hamby, S. E., Goodall, A. H., Nelson, C. P., Sakalihasan, N., Courtois, A., Ferrell, R. E., Eriksson, P., Folkersen, L., Franco-Cereceda, A., Eicher, J. D., Johnson, A. D., Betsholtz, C., Ruusalepp, A., Franzén, O., Schadt, E. E., Björkegren, J. L. M., Lipovich, L., Drolet, A. M., Verhoeven, E. L., Zeebregts, C. J., Geelkerken, R. H., Van Sambeek, M. R., Van Sterkenburg, S. M., De Vries, J. P., Stefansson, K., Thompson, J. R., De Bakker, P. I. W., Deloukas, P., Sayers, R. D., Harrison, S. C., Van Rij, A. M., Samani, N. J. & Bown, M. J., Jan 20 2017, In : Circulation Research. 120, 2, p. 341-353 13 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Abdominal Aortic Aneurysm
Meta-Analysis
Validation Studies
Risk Management
3 Citations (Scopus)

NFAT5 and SLC4A10 loci associate with plasma osmolality

Böger, C. A., Gorski, M., McMahon, G. M., Xu, H., Chang, Y. P. C., Van Der Most, P. J., Navis, G., Nolte, I. M., De Borst, M. H., Zhang, W., Lehne, B., Loh, M., Tan, S. T., Boerwinkle, E., Grams, M. E., Sekula, P., Li, M., Wilmot, B., Moon, J. G., Scheet, P. & 86 others, Cucca, F., Xiao, X., Lyytikäinen, L. P., Delgado, G., Grammer, T. B., Kleber, M. E., Sedaghat, S., Rivadeneira, F., Corre, T., Kutalik, Z., Bergmann, S., Nielson, C. M., Srikanth, P., Teumer, A., Müller-Nurasyid, M., Brockhaus, A. C., Pfeufer, A., Rathmann, W., Peters, A., Matsumoto, M., De Andrade, M., Atkinson, E. J., Robinson-Cohen, C., De Boer, I. H., Hwang, S. J., Heid, I. M., Gögele, M., Concas, M. P., Tanaka, T., Bandinelli, S., Nalls, M. A., Singleton, A., Tajuddin, S. M., Adeyemo, A., Zhou, J., Doumatey, A., McWeeney, S., Murabito, J., Franceschini, N., Flessner, M., Shlipak, M., Wilson, J. G., Chen, G., Rotimi, C. N., Zonderman, A. B., Evans, M. K., Ferrucci, L., Devuyst, O., Pirastu, M., Shuldiner, A., Hicks, A. A., Pramstaller, P. P., Kestenbaum, B., Kardia, S. L. R., Turner, S. T., Study, L. C., Briske, T. E., Gieger, C., Strauch, K., Meisinger, C., Meitinger, T., Völker, U., Nauck, M., Völzke, H., Vollenweider, P., Bochud, M., Waeber, G., Kähönen, M., Lehtimäki, T., März, W., Dehghan, A., Franco, O. H., Uitterlinden, A. G., Hofman, A., Taylor, H. A., Chambers, J. C., Kooner, J. S., Fox, C. S., Hitzemann, R., Orwoll, E. S., Pattaro, C., Schlessinger, D., Köttgen, A., Snieder, H., Parsa, A. & Cohen, D. M., Aug 1 2017, In : Journal of the American Society of Nephrology. 28, 8, p. 2311-2321 11 p.

Research output: Contribution to journalArticle

Osmolar Concentration
Meta-Analysis
Water
Sodium
Hypernatremia
1 Citation (Scopus)

Parametric Linkage Analysis Identifies Five Novel Genome-Wide Significant Loci for Familial Lung Cancer

Musolf, A. M., Simpson, C. L., De Andrade, M., Mandal, D., Gaba, C., Yang, P., Li, Y., You, M., Kupert, E. Y., Anderson, M. W., Schwartz, A. G., Pinney, S. M., Amos, C. I. & Bailey-Wilson, J. E., Aug 18 2017, (Accepted/In press) In : Human Heredity. p. 64-74 11 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Genome
Genetic Loci
Gene Frequency
Germ Cells
114 Citations (Scopus)

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

LifeLines Cohort study group, Feb 1 2017, In : The Lancet Diabetes and Endocrinology. 5, 2, p. 97-105 9 p.

Research output: Contribution to journalArticle

Random Allocation
LDL Cholesterol
Type 2 Diabetes Mellitus
Fasting
Waist-Hip Ratio
4 Citations (Scopus)

Stress hormones concentrations in the normal microenvironment predict risk for chemically induced cancer in rats

Valente, V. B., Verza, F. A., Lopes, F. Y. K., Ferreira, J. Z., dos Santos, P. S. P., Sundefeld, M. L. M. M., Biasoli, É. R., Miyahara, G. I., Soubhia, A. M. P., De Andrade, M., de Oliveira, S. H. P. & Bernabé, D. G., Jan 1 2017, (Accepted/In press) In : Psychoneuroendocrinology.

Research output: Contribution to journalArticle

Carcinogens
Hormones
Norepinephrine
Corticosterone
Brain-Derived Neurotrophic Factor
4 Citations (Scopus)

Taller height as a risk factor for venous thromboembolism: a Mendelian randomization meta-analysis

Roetker, N. S., Armasu, S. M., Pankow, J. S., Lutsey, P. L., Tang, W., Rosenberg, M. A., Palmer, T. M., MacLehose, R. F., Heckbert, S. R., Cushman, M., De Andrade, M. & Folsom, A. R., Jul 1 2017, In : Journal of Thrombosis and Haemostasis. 15, 7, p. 1334-1343 10 p.

Research output: Contribution to journalArticle

Mendelian Randomization Analysis
Venous Thromboembolism
Meta-Analysis
Odds Ratio
Confidence Intervals
7 Citations (Scopus)

Variations in primary sclerosing cholangitis across the age spectrum

Eaton, J. E., McCauley, B. M., Atkinson, E. J., Juran, B. D., Schlicht, E. M., De Andrade, M. & Lazaridis, K. N., Oct 1 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, 10, p. 1763-1768 6 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Delayed Diagnosis
Early Diagnosis
Confidence Intervals
Cholangiocarcinoma
2016
13 Citations (Scopus)

Adenocarcinoma in situ, minimally invasive adenocarcinoma, and invasive pulmonary adenocarcinoma - Analysis of interobserver agreement, survival, radiographic characteristics, and gross pathology in 296 nodules

Boland, J. M., Froemming, A. T., Wampfler, J. A., Maldonado, F., Peikert, T. D., Hyland, C., De Andrade, M., Aubry, M. C., Yang, P. & Yi, E. S., May 1 2016, In : Human Pathology. 51, p. 41-50 10 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Pathology
Survival
Adenocarcinoma in Situ
Adenocarcinoma of lung
2 Citations (Scopus)

Bayesian Variable Selection in Multilevel Item Response Theory Models with Application in Genomics

Fragoso, T. M., De Andrade, M., Pereira, A. C., Rosa, G. J. M. & Soler, J. M. P., Apr 1 2016, In : Genetic Epidemiology. 40, 3, p. 253-263 11 p.

Research output: Contribution to journalArticle

Markov Chains
Genomics
Genetic Markers
6 Citations (Scopus)

Cohort profile: The Baependi Heart Study - A family-based, highly admixed cohort study in a rural Brazilian town

Egan, K. J., Von Schantz, M., Negrão, A. B., Santos, H. C., Horimoto, A. R. V. R., Duarte, N. E., Gonçalves, G. C., Soler, J. M. P., De Andrade, M., Lorenzi-Filho, G., Vallada, H., Taporoski, T. P., Pedrazzoli, M., Azambuja, A. P., De Oliveira, C. M., Alvim, R. O., Krieger, J. E. & Pereira, A. C., Oct 1 2016, In : BMJ Open. 6, 10, e011598.

Research output: Contribution to journalReview article

Sleep
Cohort Studies
Circadian Rhythm
Cardiovascular Diseases
Electricity
10 Citations (Scopus)

EMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants

Verma, A., Verma, S. S., Pendergrass, S. A., Crawford, D. C., Crosslin, D. R., Kuivaniemi, H., Bush, W. S., Bradford, Y., Kullo, I. J., Bielinski, S. J., Li, R., Denny, J. C., Peissig, P., Hebbring, S., De Andrade, M., Ritchie, M. D. & Tromp, G., Aug 12 2016, In : BMC Medical Genomics. 9, 32.

Research output: Contribution to journalArticle

International Classification of Diseases
Electronic Health Records
Genomics
Phenotype
Clinical Studies
14 Citations (Scopus)

Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium

eMERGE Network, NEIGHBOR Consortium, Heit, J. & Pathak, J., Sep 1 2016, In : PLoS Genetics. 12, 9, e1006186.

Research output: Contribution to journalArticle

Genetic Epistasis
glaucoma
Electronic Health Records
epistasis
Genomics
10 Citations (Scopus)

Focused analysis of exome sequencing data for rare germline mutations in familial and sporadic lung cancer

Liu, Y., Kheradmand, F., Davis, C. F., Scheurer, M. E., Wheeler, D., Tsavachidis, S., Armstrong, G., Simpson, C., Mandal, D., Kupert, E., Anderson, M., You, M., Xiong, D., Pikielny, C., Schwartz, A. G., Bailey-Wilson, J., Gaba, C., De Andrade, M., Yang, P., Pinney, S. M. & 2 others, Amos, C. I. & Spitz, M. R., 2016, In : Journal of Thoracic Oncology. 11, 1, p. 52-61 10 p.

Research output: Contribution to journalArticle

Exome
Germ-Line Mutation
Lung Neoplasms
Mutation
Genome-Wide Association Study
145 Citations (Scopus)

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Pattaro, C., Teumer, A., Gorski, M., Chu, A. Y., Li, M., Mijatovic, V., Garnaas, M., Tin, A., Sorice, R., Li, Y., Taliun, D., Olden, M., Foster, M., Yang, Q., Chen, M. H., Pers, T. H., Johnson, A. D., Ko, Y. A., Fuchsberger, C., Tayo, B. & 678 others, Nalls, M., Feitosa, M. F., Isaacs, A., Dehghan, A., D'Adamo, P., Adeyemo, A., Dieffenbach, A. K., Zonderman, A. B., Nolte, I. M., Van Der Most, P. J., Wright, A. F., Shuldiner, A. R., Morrison, A. C., Hofman, A., Smith, A. V., Dreisbach, A. W., Franke, A., Uitterlinden, A. G., Metspalu, A., Tonjes, A., Lupo, A., Robino, A., Johansson, Å., Demirkan, A., Kollerits, B., Freedman, B. I., Ponte, B., Oostra, B. A., Paulweber, B., Krämer, B. K., Mitchell, B. D., Buckley, B. M., Peralta, C. A., Hayward, C., Helmer, C., Rotimi, C. N., Shaffer, C. M., Müller, C., Sala, C., Van Duijn, C. M., Saint-Pierre, A., Ackermann, D., Shriner, D., Ruggiero, D., Toniolo, D., Lu, Y., Cusi, D., Czamara, D., Ellinghaus, D., Siscovick, D. S., Ruderfer, D., Gieger, C., Grallert, H., Rochtchina, E., Atkinson, E. J., Holliday, E. G., Boerwinkle, E., Salvi, E., Bottinger, E. P., Murgia, F., Rivadeneira, F., Ernst, F., Kronenberg, F., Hu, F. B., Navis, G. J., Curhan, G. C., Ehret, G. B., Homuth, G., Coassin, S., Thun, G. A., Pistis, G., Gambaro, G., Malerba, G., Montgomery, G. W., Eiriksdottir, G., Jacobs, G., Li, G., Wichmann, H. E., Campbell, H., Schmidt, H., Wallaschofski, H., Völzke, H., Brenner, H., Kroemer, H. K., Kramer, H., Lin, H., Leach, I. M., Ford, I., Guessous, I., Rudan, I., Prokopenko, I., Borecki, I., Heid, I. M., Kolcic, I., Persico, I., Jukema, J. W., Wilson, J. F., Felix, J. F., Divers, J., Lambert, J. C., Stafford, J. M., Gaspoz, J. M., Smith, J. A., Faul, J. D., Wang, J. J., Ding, J., Hirschhorn, J. N., Attia, J., Whitfield, J. B., Chalmers, J., Viikari, J., Coresh, J., Denny, J. C., Karjalainen, J., Fernandes, J. K., Endlich, K., Butterbach, K., Keene, K. L., Lohman, K., Portas, L., Launer, L. J., Lyytikäinen, L. P., Yengo, L., Franke, L., Ferrucci, L., Rose, L. M., Kedenko, L., Rao, M., Struchalin, M., Kleber, M. E., Cavalieri, M., Haun, M., Cornelis, M. C., Ciullo, M., Pirastu, M., De Andrade, M., McEvoy, M. A., Woodward, M., Adam, M., Cocca, M., Nauck, M., Imboden, M., Waldenberger, M., Pruijm, M., Metzger, M., Stumvoll, M., Evans, M. K., Sale, M. M., Kähönen, M., Boban, M., Bochud, M., Rheinberger, M., Verweij, N., Bouatia-Naji, N., Martin, N. G., Hastie, N., Probst-Hensch, N., Soranzo, N., Devuyst, O., Raitakari, O., Gottesman, O., Franco, O. H., Polasek, O., Gasparini, P., Munroe, P. B., Ridker, P. M., Mitchell, P., Muntner, P., Meisinger, C., Smit, J. H., Abecasis, G. R., Adair, L. S., Alexander, M., Altshuler, D., Amin, N., Arking, D. E., Arora, P., Aulchenko, Y., Bakker, S. J. L., Bandinelli, S., Barroso, I., Beckmann, J. S., Beilby, J. P., Bergman, R. N., Bergmann, S., Bis, J. C., Boehnke, M., Bonnycastle, L. L., Bornstein, S. R., Bots, M. L., Bragg-Gresham, J. L., Brand, S. M., Brand, E., Braund, P. S., Brown, M. J., Burton, P. R., Casas, J. P., Caulfield, M. J., Chakravarti, A., Chambers, J. C., Chandak, G. R., Chang, Y. P. C., Charchar, F. J., Chaturvedi, N., Cho, Y. S., Clarke, R., Collins, F. S., Collins, R., Connell, J. M., Cooper, J. A., Cooper, M. N., Cooper, R. S., Corsi, A. M., Dörr, M., Dahgam, S., Danesh, J., Smith, G. D., Day, I. N. M., Deloukas, P., Denniff, M., Dominiczak, A. F., Dong, Y., Doumatey, A., Elliott, P., Elosua, R., Erdmann, J., Eyheramendy, S., Farrall, M., Fava, C., Forrester, T., Fowkes, F. G. R., Fox, E. R., Frayling, T. M., Galan, P., Ganesh, S. K., Garcia, M., Gaunt, T. R., Glazer, N. L., Go, M. J., Goel, A., Grässler, J., Grobbee, D. E., Groop, L., Guarrera, S., Guo, X., Hadley, D., Hamsten, A., Han, B. G., Hardy, R., Hartikainen, A. L., Heath, S., Heckbert, S. R., Hedblad, B., Hercberg, S., Hernandez, D., Hicks, A. A., Hilton, G., Hingorani, A. D., Hoffman Bolton, J. A., Hopewell, J. C., Howard, P., Humphries, S. E., Hunt, S. C., Hveem, K., Ikram, M. A., Islam, M., Iwai, N., Jarvelin, M. R., Jackson, A. U., Jafar, T. H., Janipalli, C. S., Johnson, T., Kathiresan, S., Khaw, K. T., Kim, H. L., Kinra, S., Kita, Y., Kivimaki, M., Kooner, J. S., Kumar, M. J. K., Kuh, D., Kulkarni, S. R., Kumari, M., Kuusisto, J., Kuznetsova, T., Laakso, M., Laan, M., Laitinen, J., Lakatta, E. G., Langefeld, C. D., Larson, M. G., Lathrop, M., Lawlor, D. A., Lawrence, R. W., Lee, J. Y., Lee, N. R., Levy, D., Li, Y., Longstreth, W. T., Luan, J., Lucas, G., Ludwig, B., Mangino, M., Mani, K. R., Marmot, M. G., Mattace-Raso, F. U. S., Matullo, G., McArdle, W. L., McKenzie, C. A., Meitinger, T., Melander, O., Meneton, P., Meschia, J. F., Miki, T., Milaneschi, Y., Mohlke, K. L., Mooser, V., Morken, M. A., Morris, R. W., Mosley, T. H., Najjar, S., Narisu, N., Newton-Cheh, C., Nguyen, K. D. H., Nilsson, P., Nyberg, F., O'Donnell, C. J., Ogihara, T., Ohkubo, T., Okamura, T., Ong, R. T. H., Ongen, H., Onland-Moret, N. C., O'Reilly, P. F., Org, E., Orru, M., Palmas, W., Palmen, J., Palmer, L. J., Palmer, N. D., Parker, A. N., Peden, J. F., Peltonen, L., Perola, M., Pihur, V., Platou, C. G. P., Plump, A., Prabhakaran, D., Psaty, B. M., Raffel, L. J., Rao, D. C., Rasheed, A., Ricceri, F., Rice, K. M., Rosengren, A., Rotter, J. I., Rudock, M. E., Sõber, S., Salako, T., Saleheen, D., Salomaa, V., Samani, N. J., Schwartz, S. M., Schwarz, P. E. H., Scott, L. J., Scott, J., Scuteri, A., Sehmi, J. S., Seielstad, M., Seshadri, S., Sharma, P., Shaw-Hawkins, S., Shi, G., Shrine, N. R. G., Sijbrands, E. J. G., Sim, X., Singleton, A., Sjögren, M., Smith, N. L., Artigas, M. S., Spector, T. D., Staessen, J. A., Stancakova, A., Steinle, N. I., Strachan, D. P., Stringham, H. M., Sun, Y. V., Swift, A. J., Tabara, Y., Tai, E. S., Talmud, P. J., Taylor, A., Terzic, J., Thelle, D. S., Tobin, M. D., Tomaszewski, M., Tripathy, V., Tuomilehto, J., Tzoulaki, I., Uda, M., Ueshima, H., Uiterwaal, C. S. P. M., Umemura, S., Van Der Harst, P., Van Der Schouw, Y. T., Van Gilst, W. H., Vartiainen, E., Vasan, R. S., Veldre, G., Verwoert, G. C., Viigimaa, M., Vinay, D. G., Vineis, P., Voight, B. F., Vollenweider, P., Wagenknecht, L. E., Wain, L. V., Wang, X., Wang, T. J., Wareham, N. J., Watkins, H., Weder, A. B., Whincup, P. H., Wiggins, K. L., Witteman, J. C. M., Wong, A., Wu, Y., Yajnik, C. S., Yao, J., Young, J. H., Zelenika, D., Zhai, G., Zhang, W., Zhang, F., Zhao, J. H., Zhu, H., Zhu, X., Zitting, P., Zukowska-Szczechowska, E., Okada, Y., Wu, J. Y., Gu, D., Takeuchi, F., Takahashi, A., Maeda, S., Tsunoda, T., Chen, P., Lim, S. C., Wong, T. Y., Liu, J., Young, T. L., Aung, T., Teo, Y. Y., Kim, Y. J., Kang, D., Chen, C. H., Tsai, F. J., Chang, L. C., Fann, S. J. C., Mei, H., Hixson, J. E., Chen, S., Katsuya, T., Isono, M., Albrecht, E., Yamamoto, K., Kubo, M., Nakamura, Y., Kamatani, N., Kato, N., He, J., Chen, Y. T., Tanaka, T., Reilly, M. P., Schunkert, H., Assimes, T. L., Hall, A., Hengstenberg, C., König, I. R., Laaksonen, R., McPherson, R., Thompson, J. R., Thorsteinsdottir, U., Ziegler, A., Absher, D., Chen, L., Cupples, L. A., Halperin, E., Li, M., Musunuru, K., Preuss, M., Schillert, A., Thorleifsson, G., Wells, G. A., Holm, H., Roberts, R., Stewart, A. F. R., Fortmann, S., Go, A., Hlatky, M., Iribarren, C., Knowles, J., Myers, R., Quertermous, T., Sidney, S., Risch, N., Tang, H., Blankenberg, S., Schnabel, R., Sinning, C., Lackner, K. J., Tiret, L., Nicaud, V., Cambien, F., Bickel, C., Rupprecht, H. J., Perret, C., Proust, C., Münzel, T. F., Barbalic, M., Chen, I. Y. D., Demissie-Banjaw, S., Folsom, A., Lumley, T., Marciante, K., Taylor, K. D., Volcik, K., Gretarsdottir, S., Gulcher, J. R., Kong, A., Stefansson, K., Thorgeirsson, G., Andersen, K., Fischer, M., Grosshennig, A., Linsel-Nitschke, P., Stark, K., Schreiber, S., Aherrahrou, Z., Bruse, P., Doering, A., Klopp, N., Diemert, P., Loley, C., Medack, A., Nahrstedt, J., Peters, A., Wagner, A. K., Willenborg, C., Böhm, B. O., Dobnig, H., Grammer, T. B., Hoffmann, M. M., Meinitzer, A., Winkelmann, B. R., Pilz, S., Renner, W., Scharnagl, H., Stojakovic, T., Tomaschitz, A., Winkler, K., Guiducci, C., Burtt, N., Gabriel, S. B., Dandona, S., Jarinova, O., Qu, L., Wilensky, R., Matthai, W., Hakonarson, H. H., Devaney, J., Burnett, M. S., Pichard, A. D., Kent, K. M., Satler, L., Lindsay, J. M., Waksman, R., Knouff, C. W., Waterworth, D. M., Walker, M. C., Epstein, S. E., Rader, D. J., Nelson, C. P., Wright, B. J., Balmforth, A. J., Ball, S. G., Loehr, L. R., Rosamond, W. D., Benjamin, E., Haritunians, T., Couper, D., Murabito, J., Wang, Y. A., Stricker, B. H., Chang, P. P., Willerson, J. T., Felix, S. B., Watzinger, N., Aragam, J., Zweiker, R., Lind, L., Rodeheffer, R. J., Greiser, K. H., Deckers, J. W., Stritzke, J., Ingelsson, E., Kullo, I. J., Haerting, J., Reffelmann, T., Redfield, M. M., Werdan, K., Mitchell, G. F., Arnett, D. K., Gottdiener, J. S., Blettner, M., Friedrich, N., Kovacs, P., Wild, P. S., Froguel, P., Rettig, R., Mägi, R., Biffar, R., Schmidt, R., Middelberg, R. P. S., Carroll, R. J., Penninx, B. W., Scott, R. J., Katz, R., Sedaghat, S., Wild, S. H., Kardia, S. L. R., Ulivi, S., Hwang, S. J., Enroth, S., Kloiber, S., Trompet, S., Stengel, B., Hancock, S. J., Turner, S. T., Rosas, S. E., Stracke, S., Harris, T. B., Zeller, T., Zemunik, T., Lehtimäki, T., Illig, T., Aspelund, T., Nikopensius, T., Esko, T., Tanaka, T., Gyllensten, U., Völker, U., Emilsson, V., Vitart, V., Aalto, V., Gudnason, V., Chouraki, V., Chen, W. M., Igl, W., März, W., Koenig, W., Lieb, W., Loos, R. J. F., Liu, Y., Snieder, H., Pramstaller, P. P., Parsa, A., O'Connell, J. R., Susztak, K., Hamet, P., Tremblay, J., De Boer, I. H., Böger, C. A., Goessling, W., Chasman, D. I., Köttgen, A., Kao, W. H. L. & Fox, C. S., Jan 21 2016, In : Nature Communications. 7, 10023.

Research output: Contribution to journalArticle

kidneys
loci
Glomerular Filtration Rate
Kidney
cells
49 Citations (Scopus)

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

The UK-PSC Consortium, The International IBD Genetics Consortium & The International PSC Study Group, Dec 19 2016, (Accepted/In press) In : Nature Genetics.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Genetic Loci
Genome-Wide Association Study
Inflammatory Bowel Diseases
Ulcerative Colitis
6 Citations (Scopus)

Impact of adiposity on cellular adhesion: The Multi-Ethnic Study of atherosclerosis (MESA)

Christoph, M. J., Allison, M. A., Pankow, J. S., Decker, P. A., Kirsch, P. S., Tsai, M. Y., Sale, M. M., De Andrade, M., Sicotte, H., Tang, W., Hanson, N. Q., Berardi, C., Wassel, C. L., Larson, N. & Bielinski, S. J., Jan 1 2016, In : Obesity. 24, 1, p. 223-230 8 p.

Research output: Contribution to journalArticle

Adiposity
Atherosclerosis
Intra-Abdominal Fat
Waist-Hip Ratio
Selectins
7 Citations (Scopus)
Menopause
Estrogens
Hormones
Conjugated (USP) Estrogens
Alleles
5 Citations (Scopus)

Is there still room for additional common susceptibility alleles for venous thromboembolism?

Trégouët, D. A., Delluc, A., Roche, A., Derbois, C., Olaso, R., Germain, M., De Andrade, M., Tang, W., Chasman, D. I., van Hylckama Vlieg, A., Reitsma, P. H., Kabrhel, C., Smith, N. & Morange, P. E., Sep 1 2016, In : Journal of Thrombosis and Haemostasis. 14, 9, p. 1798-1802 5 p.

Research output: Contribution to journalArticle

Venous Thromboembolism
Alleles
Single Nucleotide Polymorphism
Venous Thrombosis
Genome-Wide Association Study
18 Citations (Scopus)

Multiple-level validation identifies PARK2 in the development of lung cancer and chronic obstructive pulmonary disease

Lee, S. B., She, J., Deng, B., Kim, J. J., De Andrade, M., Na, J., Sun, Z. D., Wampfler, J. A., Cunningham, J. M., Wu, Y., Limper, A. H., Aubry, M. C., Wendt, C., Biterman, P., Yang, P. & Lou, Z., 2016, In : Oncotarget. 7, 28, p. 44211-44223 13 p.

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Lung Neoplasms
Genomic Instability
Inflammation
Chromosomal Instability
13 Citations (Scopus)

Pharmacogenomics of estrogens on changes in carotid artery intima-medial thickness and coronary arterial calcification: Kronos Early Estrogen Prevention Study

Miller, V. M., Jenkins, G. D., Biernacka, J. M., Heit, J. A., Huggins, G. S., Hodis, H. N., Budoff, M. J., Lobo, R. A., Taylor, H. S., Manson, J. E., Black, D. M., Naftolin, F., Mitchell Harman, S. & De Andrade, M., Jan 1 2016, In : Physiological Genomics. 48, 1, p. 33-41 9 p.

Research output: Contribution to journalArticle

Pharmacogenetics
Carotid Arteries
Estrogens
Innate Immunity
Hormones
16 Citations (Scopus)

Sex-specific genetic variants are associated with coronary endothelial dysfunction

Yoshino, S., Cilluffo, R., Prasad, M., Best, P., Atkinson, E. J., Aoki, T., Cunningham, J. M., De Andrade, M., Lerman, L. O. & Lerman, A., 2016, In : Journal of the American Heart Association. 5, 4, e002544.

Research output: Contribution to journalArticle

Single Nucleotide Polymorphism
Blood Vessels
Atherosclerosis
Coronary Vessels
Acetylcholine
9 Citations (Scopus)

Shared genetic risk factors of intracranial, abdominal, and thoracic aneurysms

Aneurysm Consortium, Vascular Research Consortium of New Zealand, Jul 1 2016, In : Journal of the American Heart Association. 5, 7, e002603.

Research output: Contribution to journalArticle

Abdominal Aortic Aneurysm
Thoracic Aortic Aneurysm
Intracranial Aneurysm
Aneurysm
Thorax