• 2396 Citations
  • 22 Scopus h-Index
19992020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 2396 Citations
  • 22 Scopus h-Index
  • 41 Article
  • 12 Review article
  • 2 Chapter
  • 2 Letter
2020

Alterations in levels of 8-Oxo-2'-deoxyguanosine and 8-Oxoguanine DNA glycosylase 1 during a current episode and after remission in unipolar and bipolar depression

Ceylan, D., Yılmaz, S., Tuna, G., Kant, M., Er, A., Ildız, A., Verim, B., Akış, M., Akan, P., İşlekel, H., Veldic, M., Frye, M. & Özerdem, A., Apr 2020, In : Psychoneuroendocrinology. 114, 104600.

Research output: Contribution to journalArticle

1 Scopus citations

Differential dorsolateral prefrontal cortex proteomic profiles of suicide victims with mood disorders

Cabello-Arreola, A., Ho, A. M. C., Ozerdem, A., Cuellar-Barboza, A. B., Kucuker, M. U., Heppelmann, C. J., Charlesworth, M. C., Ceylan, D., Stockmeier, C. A., Rajkowska, G., Frye, M. A., Choi, D. S. & Veldic, M., Mar 2020, In : Genes. 11, 3, 256.

Research output: Contribution to journalArticle

Open Access

Dissecting the epigenetic changes induced by non-antipsychotic mood stabilizers on schizophrenia and affective disorders: A systematic review

Gardea-Resendez, M., Kucuker, M. U., Blacker, C. J., Ho, A. M. C., Croarkin, P. E., Frye, M. A. & Veldic, M., Apr 22 2020, In : Frontiers in Pharmacology. 11, 467.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Label-free proteomics differences in the dorsolateral prefrontal cortex between bipolar disorder patients with and without psychosis

Ho, A. M. C., Cabello-Arreola, A., Markota, M., Heppelmann, C. J., Charlesworth, M. C., Ozerdem, A., Mahajan, G., Rajkowska, G., Stockmeier, C. A., Frye, M. A., Choi, D. S. & Veldic, M., Jun 1 2020, In : Journal of Affective Disorders. 270, p. 165-173 9 p.

Research output: Contribution to journalArticle

Open Access

Methylation of Brain Derived Neurotrophic Factor (BDNF) Val66Met CpG site is associated with early onset bipolar disorder

Nassan, M., Veldic, M., Winham, S., Frye, M. A., Larrabee, B., Colby, C., Biernacka, J., Bellia, F., Pucci, M., Terenius, L., Vukojevic, V. & D´Addario, C., Apr 15 2020, In : Journal of Affective Disorders. 267, p. 96-102 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Potential pharmacogenomic targets in bipolar disorder: considerations for current testing and the development of decision support tools to individualize treatment selection

Cuéllar-Barboza, A. B., McElroy, S. L., Veldic, M. D., Singh, B., Kung, S. M., Romo-Nava, F., Nunez, N. A., Cabello-Arreola, A., Coombes, B. J., Prieto, M., Betcher, H. K., Moore, K. M., Winham, S. J., Biernacka, J. M. & Frye, M. A., Dec 1 2020, In : International Journal of Bipolar Disorders. 8, 1, 23.

Research output: Contribution to journalReview article

Open Access

The relationship between DNA methylation and antidepressant medications: A systematic review

Webb, L. M., Phillips, K. E., Ho, M. C., Veldic, M. & Blacker, C. J., Feb 1 2020, In : International journal of molecular sciences. 21, 3, 826.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations
2019

A review of epigenetics of PTSD in comorbid psychiatric conditions

Blacker, C. J., Frye, M. A., Morava, E., Kozicz, T. & Veldic, M., Feb 2019, In : Genes. 10, 2, 140.

Research output: Contribution to journalReview article

Open Access
5 Scopus citations

Association of Cytomegalovirus and Toxoplasma gondii Antibody Titers with Bipolar Disorder

Frye, M. A., Coombes, B. J., McElroy, S. L., Jones-Brando, L., Bond, D. J., Veldic, M. D., Romo-Nava, F., Bobo, W. V., Singh, B., Colby, C., Skime, M. K., Biernacka, J. M. & Yolken, R., Jan 1 2019, (Accepted/In press) In : JAMA Psychiatry.

Research output: Contribution to journalArticle

1 Scopus citations

Chronic caffeine exposure in adolescence promotes diurnal, biphasic mood-cycling and enhanced motivation for reward in adult mice

Hinton, D. J., Andres-Beck, L. G., Nett, K. E., Oliveros, A., Choi, S., Veldic, M. D. & Choi, D. S., Sep 16 2019, In : Behavioural Brain Research. 370, 111943.

Research output: Contribution to journalArticle

Cytochrome P450 2C19 poor metabolizer phenotype in treatment resistant depression: Treatment and diagnostic implications

Veldic, M., Ahmed, A. T., Blacker, C. J., Geske, J. R., Biernacka, J. M., Borreggine, K. L., Moore, K. M., Prieto, M. L., Vande Voort, J. L., Croarkin, P. E., Hoberg, A. A., Kung, S., Alarcon, R. D., Keeth, N., Singh, B., Bobo, W. V. & Frye, M. A., 2019, In : Frontiers in Pharmacology. 10, FEB, 83.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Efficacy and tolerability of adjunctive modafinil/armodafinil in bipolar depression: A meta-analysis of randomized controlled trials

Nunez, N. A., Singh, B., Romo-Nava, F., Joseph, B., Veldic, M., Cuellar-Barboza, A., Cabello Arreola, A., Vande Voort, J. L., Croarkin, P., Moore, K. M., Biernacka, J., McElroy, S. L. & Frye, M. A., Jan 1 2019, (Accepted/In press) In : Bipolar disorders.

Research output: Contribution to journalReview article

1 Scopus citations

Genetic variant in SLC1A2 is associated with elevated anterior cingulate cortex glutamate and lifetime history of rapid cycling

Veldic, M., Millischer, V., Port, J. D., Ho, A. M. C., Jia, Y. F., Geske, J. R., Biernacka, J. M., Backlund, L., McElroy, S. L., Bond, D. J., Villaescusa, J. C., Skime, M., Choi, D. S., Lavebratt, C., Schalling, M. & Frye, M. A., Dec 1 2019, In : Translational psychiatry. 9, 1, 149.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Genome-wide DNA methylomic differences between dorsolateral prefrontal and temporal pole cortices of bipolar disorder

Ho, A. M. C., Winham, S. J., Armasu, S. M., Blacker, C. J., Millischer, V., Lavebratt, C., Overholser, J. C., Jurjus, G. J., Dieter, L., Mahajan, G., Rajkowska, G., Vallender, E. J., Stockmeier, C. A., Robertson, K. D., Frye, M. A., Choi, D. S. & Veldic, M., Oct 1 2019, In : Journal of Psychiatric Research. 117, p. 45-54 10 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Increased plasma levels of 8-oxoguanine DNA glycosylase-1 in bipolar disorder

Ceylan, D., Yılmaz, S., Bora, U., Tuna, G., Ildız, A., Akan, P., Veldic, M., Frye, M. A. & Özerdem, A., Nov 1 2019, In : Psychiatry and Clinical Neurosciences. 73, 11, p. 719-720 2 p.

Research output: Contribution to journalLetter

4 Scopus citations

Type 1 equilibrative nucleoside transporter (ENT1) regulates sex-specific ethanol drinking during disruption of circadian rhythms

Jia, Y. F., Vadnie, C. A., Ho, A. M. C., Peyton, L., Veldic, M. D., Wininger, K., Matveyenko, A. V. & Choi, D. S., Jan 1 2019, In : Addiction Biology. e12801.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Association of schizophrenia polygenic risk score with manic and depressive psychosis in bipolar disorder

Markota, M., Coombes, B. J., Larrabee, B. R., McElroy, S. L., Bond, D. J., Veldic, M., Colby, C. L., Chauhan, M., Cuellar-Barboza, A. B., Fuentes, M., Kung, S. M., Prieto, M. L., Rummans, T. A., Bobo, W. V., Frye, M. A. & Biernacka, J. M., Dec 1 2018, In : Translational Psychiatry. 8, 1, 188.

Research output: Contribution to journalArticle

12 Scopus citations
2017

A genome wide association study suggests the association of muskelin with early onset bipolar disorder: Implications for a GABAergic epileptogenic neurogenesis model

Nassan, M., Li, Q., Croarkin, P. E., Chen, W., Colby, C. L., Veldic, M. D., McElroy, S. L., Jenkins, G. D., Ryu, E., Cunningham, J. M., Leboyer, M., Frye, M. A. & Biernacka, J. M., Jan 15 2017, In : Journal of Affective Disorders. 208, p. 120-129 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Differential SLC1A2 promoter methylation in bipolar disorder with or without addiction

Jia, Y. F., Choi, Y. B., Ayers-Ringler, J. R., Biernacka, J. M., Geske, J. R., Lindberg, D. R., McElroy, S. L., Frye, M. A., Choi, D. S. & Veldic, M., Jul 21 2017, In : Frontiers in Cellular Neuroscience. 11, 217.

Research output: Contribution to journalArticle

11 Scopus citations

Exploring hepsin functional genetic variation association with disease specific protein expression in bipolar disorder: Applications of a proteomic informed genomic approach

Nassan, M., Jia, Y. F., Jenkins, G., Colby, C., Feeder, S., Choi, D. S., Veldic, M. D., McElroy, S. L., Bond, D. J., Weinshilboum, R. M., Biernacka, J. M. & Frye, M. A., Dec 1 2017, In : Journal of Psychiatric Research. 95, p. 208-212 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Genetic risk score analysis in early-onset bipolar disorder

Croarkin, P. E., Luby, J. L., Cercy, K., Geske, J. R., Veldic, M. D., Simonson, M., Joshi, P. T., Wagner, K. D., Walkup, J. T., Nassan, M. M., Cuellar-Barboza, A. B., Casuto, L., McElroy, S. L., Jensen, P. S., Frye, M. A. & Biernacka, J. M., Nov 1 2017, In : Journal of Clinical Psychiatry. 78, 9, p. 1337-1343 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Metabotropic glutamate receptors as emerging research targets in bipolar disorder

Blacker, C. J., Lewis, C. P., Frye, M. A. & Veldic, M. D., Nov 1 2017, In : Psychiatry Research. 257, p. 327-337 11 p.

Research output: Contribution to journalReview article

9 Scopus citations
2016

Clinical features of bipolar spectrum with binge eating behaviour

McElroy, S. L., Crow, S., Blom, T. J., Cuellar-Barboza, A. B., Prieto, M. L., Veldic, M. D., Winham, S. J., Bobo, W. V., Geske, J., Seymour, L. R., Mori, N., Bond, D. J., Biernacka, J. M. & Frye, M. A., Sep 1 2016, In : Journal of Affective Disorders. 201, p. 95-98 4 p.

Research output: Contribution to journalArticle

15 Scopus citations

Prevalence and correlates of DSM-5 eating disorders in patients with bipolar disorder

McElroy, S. L., Crow, S., Blom, T. J., Biernacka, J. M., Winham, S. J., Geske, J., Cuellar-Barboza, A. B., Bobo, W. V., Prieto, M. L., Veldic, M. D., Mori, N., Seymour, L. R., Bond, D. J. & Frye, M. A., Feb 1 2016, In : Journal of Affective Disorders. 191, p. 216-221 6 p.

Research output: Contribution to journalArticle

34 Scopus citations
2015

Association of brain-derived neurotrophic factor (BDNF) Val66Met polymorphism with early-onset bipolar disorder

Nassan, M., Croarkin, P. E., Luby, J. L., Veldic, M. D., Joshi, P. T., Mcelroy, S. L., Post, R. M., Walkup, J. T., Cercy, K., Geske, J. R., Wagner, K. D., Cuellar-Barboza, A. B., Casuto, L., Lavebratt, C., Schalling, M., Jensen, P. S., Biernacka, J. M. & Frye, M. A., Sep 1 2015, In : Bipolar Disorders. 17, 6, p. 645-652 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Clinical risk factors and serotonin transporter gene variants associated with antidepressant-induced mania

Frye, M. A., McElroy, S. L., Prieto, M. L., Harper, K. L., Walker, D. L., Kung, S., Chauhan, M., Crow, S., Sutor, B., Galardy, C. W., Veldic, M. D., Palmer, B. A., Geske, J. R., Fuentes, M., Cuellar-Barboza, A. B., Seymour, L. R., Mori, N. & Biernacka, J. M., Feb 1 2015, In : The Journal of clinical psychiatry. 76, 2, p. 174-180 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Development of a bipolar disorder biobank: differential phenotyping for subsequent biomarker analyses

Frye, M. A., McElroy, S. L., Fuentes, M., Sutor, B., Schak, K. D., Galardy, C. W., Palmer, B. A., Prieto, M. L., Kung, S. M., Sola, C. L., Ryu, E., Veldic, M., Geske, J., Cuellar-Barboza, A., Seymour, L. R., Mori, N., Crowe, S., Rummans, T. A. & Biernacka, J. M., Dec 30 2015, In : International Journal of Bipolar Disorders. 3, 1, 14.

Research output: Contribution to journalArticle

30 Scopus citations

Feasibility of investigating differential proteomic expression in depression: implications for biomarker development in mood disorders

Frye, M. A., Nassan, M., Jenkins, G. D., Kung, S., Veldic, M. D., Palmer, B. A., Feeder, S. E., Tye, S. J., Choi, D. S. & Biernacka, J. M., 2015, In : Translational Psychiatry. 5, p. e689

Research output: Contribution to journalArticle

22 Scopus citations

Feasibility of investigating differential proteomic expression in depression: Implications for biomarker development in mood disorders

Frye, M. A., Nassan, M., Jenkins, G. D., Kung, S., Veldic, M. D., Palmer, B. A., Feeder, S. E., Tye, S. J., Choi, D. S. & Biernacka, J. M., Dec 1 2015, In : Translational Psychiatry. 5, e687.

Research output: Contribution to journalArticle

5 Scopus citations
2014

Current landscape, unmet needs, and future directions for treatment of bipolar depression

Frye, M. A., Prieto, M. L., Bobo, W. V., Kung, S., Veldic, M., Alarcon, R. D., Moore, K. M., Choi, D. S., Biernacka, J. M. & Tye, S. J., Dec 1 2014, In : Journal of Affective Disorders. 169, S1, p. S17-S23

Research output: Contribution to journalReview article

25 Scopus citations
2013

DNA Methylation/Demethylation Network Expression in Psychotic Patients with a History of Alcohol Abuse

Guidotti, A., Dong, E., Gavin, D. P., Veldic, M., Zhao, W., Bhaumik, D. K., Pandey, S. C. & Grayson, D. R., Mar 1 2013, In : Alcoholism: Clinical and Experimental Research. 37, 3, p. 417-424 8 p.

Research output: Contribution to journalArticle

23 Scopus citations
2012

Pharmacogenomics of antidepressant induced mania: A review and meta-analysis of the serotonin transporter gene (5HTTLPR) association

Biernacka, J. M., McElroy, S. L., Crow, S., Sharp, A., Benitez, J., Veldic, M., Kung, S., Cunningham, J. M., Post, R. M., Mrazek, D. & Frye, M. A., Jan 1 2012, In : Journal of Affective Disorders. 136, 1-2, p. e21-e29

Research output: Contribution to journalReview article

22 Scopus citations
2010

L-methionine decreases dendritic spine density in mouse frontal cortex

Tueting, P., Davis, J. M., Veldic, M., Pibiri, F., Kadriu, B., Guidotti, A. & Costa, E., Jun 1 2010, In : NeuroReport. 21, 8, p. 543-548 6 p.

Research output: Contribution to journalArticle

14 Scopus citations
2009

An upregulation of DNA-methyltransferase 1 and 3a expressed in telencephalic GABAergic neurons of schizophrenia patients is also detected in peripheral blood lymphocytes

Zhubi, A., Veldic, M., Puri, N. V., Kadriu, B., Caruncho, H., Loza, I., Sershen, H., Lajtha, A., Smith, R. C., Guidotti, A., Davis, J. M. & Costa, E., Jun 1 2009, In : Schizophrenia Research. 111, 1-3, p. 115-122 8 p.

Research output: Contribution to journalArticle

92 Scopus citations

GABAergic promoter hypermethylation as a model to study the neurochemistry of schizophrenia vulnerability

Costa, E., Chen, Y., Dong, E., Grayson, D. R., Kundakovic, M., Maloku, E., Ruzicka, W., Satta, R., Veldic, M., Zhubi, A. & Guidotti, A., Jan 1 2009, In : Expert review of neurotherapeutics. 9, 1, p. 87-98 12 p.

Research output: Contribution to journalReview article

53 Scopus citations
2008

Reelin downregulation as a prospective treatment target for GABAergic dysfunction in schizophrenia

Costa, E., Chen, Y., Dong, E., Grayson, D. R., Guidotti, A. & Veldic, M., Jan 1 2008, Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease. Springer New York, p. 341-363 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
2007

Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder

Veldic, M., Kadriu, B., Maloku, E., Agis-Balboa, R. C., Guidotti, A., Davis, J. M. & Costa, E., Mar 1 2007, In : Schizophrenia Research. 91, 1-3, p. 51-61 11 p.

Research output: Contribution to journalArticle

124 Scopus citations

Reviewing the role of DNA (cytosine-5) methyltransferase overexpression in the cortical GABAergic dysfunction associated with psychosis vulnerability

Costa, E., Dong, E., Grayson, D. R., Guidotti, A., Ruzicka, W. & Veldic, M., 2007, In : Epigenetics. 2, 1, p. 29-36 8 p.

Research output: Contribution to journalReview article

Open Access
76 Scopus citations

S-adenosyl methionine and DNA methyltransferase-1 mRNA overexpression in psychosis

Guidotti, A., Ruzicka, W., Grayson, D. R., Veldic, M., Pinna, G., Davis, J. M. & Costa, E., Jan 1 2007, In : NeuroReport. 18, 1, p. 57-60 4 p.

Research output: Contribution to journalArticle

82 Scopus citations

Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection

Ruzicka, W. B., Zhubi, A., Veldic, M., Grayson, D. R., Costa, E. & Guidotti, A., Apr 30 2007, In : Molecular Psychiatry. 12, 4, p. 385-397 13 p.

Research output: Contribution to journalArticle

136 Scopus citations
2006

Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis

Agís-Balboa, R. C., Pinna, G., Zhubi, A., Maloku, E., Veldic, M., Costa, E. & Guidotti, A., Sep 26 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 39, p. 14602-14607 6 p.

Research output: Contribution to journalArticle

248 Scopus citations

Epigenetic Targets in GABAergic Neurons to Treat Schizophrenia

Costa, E., Dong, E., Grayson, D. R., Ruzicka, W. B., Simonini, M. V., Veldic, M. & Guidotti, A., Dec 1 2006, GABA. Enna, S. J. (ed.). p. 95-117 23 p. (Advances in Pharmacology; vol. 54).

Research output: Chapter in Book/Report/Conference proceedingChapter

22 Scopus citations

The benzamide MS-275 is a potent, long-lasting brain region-selective inhibitor of histone deacetylases

Simonini, M. V., Camargo, L. M., Dong, E., Maloku, E., Veldic, M., Costa, E. & Guidotti, A., Jan 31 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 5, p. 1587-1592 6 p.

Research output: Contribution to journalArticle

175 Scopus citations
2005

DNA methyltransferase 1 regulates reelin mRNA expression in mouse primary cortical cultures

Jai, S. N., Sharma, R. P., Veldic, M., Salvacion, A. A., Jia, X., Chen, Y., Costa, E., Guidotti, A. & Grayson, D. R., Feb 1 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 5, p. 1749-1754 6 p.

Research output: Contribution to journalArticle

109 Scopus citations

GABAergic dysfunction in schizophrenia: New treatment strategies on the horizon

Guidotti, A., Auta, J., Davis, J. M., Dong, E., Grayson, D. R., Veldic, M., Zhang, X. & Costa, E., Jul 1 2005, In : Psychopharmacology. 180, 2, p. 191-205 15 p.

Research output: Contribution to journalArticle

217 Scopus citations

In psychosis, cortical interneurons overexpress DNA-methyltransferase 1

Veldic, M., Guidotti, A., Maloku, E., Davis, J. M. & Costa, E., Feb 8 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 6, p. 2152-2157 6 p.

Research output: Contribution to journalArticle

218 Scopus citations

Should allosteric positive modulators of GABA A receptors be tested in the treatment of schizophrenia? [1]

Costa, E., Guidotti, A. & Veldić, M., Mar 1 2005, In : Schizophrenia Research. 73, 2-3, p. 367-368 2 p.

Research output: Contribution to journalLetter

7 Scopus citations
2004

A GABAergic cortical deficit dominates schizophrenia pathophysiology

Costa, E., Davis, J. M., Dong, E., Grayson, D. R., Guidotti, A., Tremolizzo, L. & Veldic, M., Dec 15 2004, In : Critical reviews in neurobiology. 16, 1-2, p. 1-23 23 p.

Research output: Contribution to journalReview article

106 Scopus citations

DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains

Veldic, M., Caruncho, H. J., Liu, W. S., Davis, J., Satta, R., Grayson, D. R., Guidotti, A. & Costa, E., Jan 1 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 1, p. 348-353 6 p.

Research output: Contribution to journalArticle

241 Scopus citations