• 321 Citations
  • 10 Scopus h-Index
20032020

Research output per year

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Research Output

2020

Broad-Spectrum Profiling of Drug Safety via Learning Complex Network

Liu, K., Ding, R. F., Xu, H., Qin, Y. M., He, Q. S., Du, F., Zhang, Y., Yao, L. X., You, P., Xiang, Y. P. & Ji, Z. L., Jun 1 2020, In : Clinical pharmacology and therapeutics. 107, 6, p. 1373-1382 10 p.

Research output: Contribution to journalArticle

Open Access

Integrative Omics Approach to Identifying Genes Associated with Atrial Fibrillation

Wang, B., Lunetta, K. L., Dupuis, J., Lubitz, S. A., Trinquart, L., Yao, L., Ellinor, P. T., Benjamin, E. J. & Lin, H., 2020, (Accepted/In press) In : Circulation research. p. 350-360 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Patient experiences and perceptions associated with the use of desiccated thyroid extract

Toloza, F. J. K., Suarez, N. R. E., El Kawkgi, O., Golembiewski, E. H., Ponce, O. J., Yao, L., Maraka, S., Ospina, N. M. S. & Brito, J. P., Apr 2020, In : Medicina (Lithuania). 56, 4, 161.

Research output: Contribution to journalArticle

Open Access

Recent advances and challenges of the drugs acting on monoamine transporters

Xue, W., Fu, T., Zheng, G., Tu, G., Zhang, Y., Yang, F., Tao, L., Yao, L. & Zhu, F., 2020, In : Current Medicinal Chemistry. 27, 23, p. 3830-3876 47 p.

Research output: Contribution to journalReview article

3 Scopus citations
2019

Detecting Serendipitous Drug Usage in Social Media with Deep Neural Network Models

Ru, B., Li, D. & Yao, L., Jan 21 2019, Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018. Schmidt, H., Griol, D., Wang, H., Baumbach, J., Zheng, H., Callejas, Z., Hu, X., Dickerson, J. & Zhang, L. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 1083-1090 8 p. 8621252. (Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
Open Access

Facilitating accurate health provider directories using natural language processing

Cook, M. J., Yao, L. & Wang, X., Apr 4 2019, In : BMC Medical Informatics and Decision Making. 19, 80.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Openhi: Open platform for histopathological image annotation

Puttapirat, P., Zhang, H., Deng, J., Dong, Y., Shi, J., Lou, P., Wang, C., Yao, L., Zhang, X. & Li, C., Jan 1 2019, In : International Journal of Data Mining and Bioinformatics. 22, 4, p. 328-349 22 p.

Research output: Contribution to journalArticle

1 Scopus citations

OpenHI - An open source framework for annotating histopathological image

Puttapirat, P., Zhang, H., Lian, Y., Wang, C., Zhang, X., Yao, L. & Li, C., Jan 21 2019, Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018. Schmidt, H., Griol, D., Wang, H., Baumbach, J., Zheng, H., Callejas, Z., Hu, X., Dickerson, J. & Zhang, L. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 1076-1082 7 p. 8621393. (Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Serendipity - A Machine-Learning Application for Mining Serendipitous Drug Usage from Social Media

Ru, B., Li, D., Hu, Y. & Yao, L., Jul 2019, In : IEEE Transactions on Nanobioscience. 18, 3, p. 324-334 11 p., 8681431.

Research output: Contribution to journalArticle

1 Scopus citations

Simultaneous Improvement in the Precision, Accuracy, and Robustness of Label-free Proteome Quantification by Optimizing Data Manipulation Chains

Tang, J., Fu, J., Wang, Y., Luo, Y., Yang, Q., Li, B., Tu, G., Hong, J., Cui, X., Chen, Y., Yao, L., Xue, W. & Zhu, F., Jan 1 2019, In : Molecular and Cellular Proteomics. 18, 8, p. 1683-1699 17 p.

Research output: Contribution to journalArticle

21 Scopus citations

Technological innovations in disease management: Text mining US patent data from 1995 to 2017

Huang, M., Zolnoori, M., Balls-Berry, J. E., Brockman, T. A., Patten, C. A. & Yao, L., Apr 2019, In : Journal of medical Internet research. 21, 4, e13316.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Temporal sequence alignment in electronic health records for computable patient representation

Huang, M., Zolnoori, M., Shah, N. D. & Yao, L., Jan 21 2019, Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018. Schmidt, H., Griol, D., Wang, H., Baumbach, J., Zheng, H., Callejas, Z., Hu, X., Dickerson, J. & Zhang, L. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 1054-1061 8 p. 8621428. (Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Understanding the patient perspective of epilepsy treatment through text mining of online patient support groups

He, K., Hong, N., Lapalme-Remis, S., Lan, Y., Huang, M., Li, C. & Yao, L., May 1 2019, In : Epilepsy and Behavior. 94, p. 65-71 7 p.

Research output: Contribution to journalArticle

Open Access
2018

ADReCS-Target: Target profiles for aiding drug safety research and application

Huang, L. H., He, Q. S., Liu, K., Cheng, J., Zhong, M. D., Chen, L. S., Yao, L. X. & Ji, Z. L., Jan 1 2018, In : Nucleic acids research. 46, D1, p. D911-D917

Research output: Contribution to journalArticle

7 Scopus citations

A feasibility study on identifying drinking-related contents in Facebook through mining heterogeneous data

ElTayeby, O., Eaglin, T., Abdullah, M., Burlinson, D., Dou, W. & Yao, L., Jan 1 2018, (Accepted/In press) In : Health Informatics Journal.

Research output: Contribution to journalArticle

3 Scopus citations

A Natural Language Processing Approach to Acquire Accurate Health Provider Directory Information

Cook, M., Yao, L. & Wang, X., Jul 16 2018, Proceedings - 2018 IEEE International Conference on Healthcare Informatics Workshops, ICHI-W 2018. Institute of Electrical and Electronics Engineers Inc., p. 76-77 2 p. 8411813

Research output: Chapter in Book/Report/Conference proceedingConference contribution

A publication-based popularity index (PPI) for healthcare dataset ranking

Shi, J., Zheng, M., Yao, L. & Ge, Y., Jul 24 2018, Proceedings - 2018 IEEE International Conference on Healthcare Informatics, ICHI 2018. Institute of Electrical and Electronics Engineers Inc., p. 247-254 8 p. 8419368. (Proceedings - 2018 IEEE International Conference on Healthcare Informatics, ICHI 2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Characterizing Treatment Strategies of Intrahepatic Bile Duct Cancer by Literature Mining

Guo, H., Zhang, N., Hong, N., Yao, L., Duan, W. & Zhang, Z., Jul 16 2018, Proceedings - 2018 IEEE International Conference on Healthcare Informatics Workshops, ICHI-W 2018. Institute of Electrical and Electronics Engineers Inc., p. 43-48 6 p. 8411679

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Computational Advances in the Label-free Quantification of Cancer Proteomics Data

Tang, J., Zhang, Y., Fu, J., Wang, Y., Li, Y., Yang, Q., Yao, L., Xue, W. & Zhu, F., Jan 1 2018, In : Current Pharmaceutical Design. 24, 32, p. 3842-3858 17 p.

Research output: Contribution to journalArticle

8 Scopus citations

Developing a healthcare dataset information resource (DIR) based on Semantic Web

Shi, J., Zheng, M., Yao, L. & Ge, Y., Nov 20 2018, In : BMC Medical Genomics. 11, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Estimating disease burden using Internet data

Qiu, R., Hadzikadic, M., Yu, S. & Yao, L., Jan 1 2018, (Accepted/In press) In : Health Informatics Journal.

Research output: Contribution to journalArticle

2 Scopus citations

MfeCNN: Mixture feature embedding convolutional neural network for data mapping

Li, D., Huang, M., Li, X., Ruan, Y. & Yao, L., Jul 1 2018, In : IEEE Transactions on Nanobioscience. 17, 3, p. 165-171 7 p., 8368078.

Research output: Contribution to journalArticle

4 Scopus citations

Predicted Arabidopsis Interactome Resource and Gene Set Linkage Analysis: A Transcriptomic Analysis Resource

Yao, H., Wang, X., Chen, P., Hai, L., Jin, K., Yao, L., Mao, C. & Chen, X., May 1 2018, In : Plant Physiology. 177, 1, p. 422-433 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Prediction of GluN2B-CT1290-1310/DAPK1 interaction by protein–peptide docking and molecular dynamics simulation

Tu, G., Fu, T., Yang, F., Yao, L., Xue, W. & Zhu, F., Nov 19 2018, In : Molecules. 23, 11, 3018.

Research output: Contribution to journalArticle

5 Scopus citations

Public opinions toward diseases: Infodemiological study on news media data

Huang, M., ElTayeby, O., Zolnoori, M. & Yao, L., May 1 2018, In : Journal of Medical Internet Research. 20, 5, e10047.

Research output: Contribution to journalArticle

7 Scopus citations

Terminology enabled spatio-temporal analysis and visualization for preterm birth data in the US

Wang, K. & Yao, L., 2018, HEALTHINF 2018 - 11th International Conference on Health Informatics, Proceedings; Part of 11th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2018. Zwiggelaar, R., Gamboa, H., Fred, A. & Bermudez i Badia, S. (eds.). SciTePress, p. 510-518 9 p. (HEALTHINF 2018 - 11th International Conference on Health Informatics, Proceedings; Part of 11th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2018; vol. 5).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
2017

ADMETNet: The knowledge base of pharmacokinetics and toxicology network

Xu, Q., Liu, K., Lin, X., Qin, Y., Chen, L., Cheng, J., Zhong, M., He, Q., Li, Y., Wang, T., Pan, J., Peng, M., Yao, L. & Ji, Z., May 20 2017, In : Journal of Genetics and Genomics. 44, 5, p. 273-276 4 p.

Research output: Contribution to journalLetter

3 Scopus citations

Detecting drinking-related contents on social media by classifying heterogeneous data types

ElTayeby, O., Eaglin, T., Abdullah, M., Burlinson, D., Dou, W. & Yao, L., Jan 1 2017, Advances in Artificial Intelligence: From Theory to Practice - 30th International Conference on Industrial Engineering and Other Applications of Applied Intelligent Systems, IEA/AIE 2017, Proceedings. Ali, M., Benferhat, S. & Tabia, K. (eds.). Springer Verlag, p. 364-373 10 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10351 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

DIR-A semantic information resource for healthcare datasets

Shi, J., Zheng, M., Yao, L. & Ge, Y., Dec 15 2017, Proceedings - 2017 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2017. Yoo, I., Zheng, J. H., Gong, Y., Hu, X. T., Shyu, C-R., Bromberg, Y., Gao, J. & Korkin, D. (eds.). Institute of Electrical and Electronics Engineers Inc., Vol. 2017-January. p. 805-810 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Estimating disease burden using google trends and Wikipedia data

Qiu, R., Hadzikadic, M. & Yao, L., Jan 1 2017, Advances in Artificial Intelligence: From Theory to Practice - 30th International Conference on Industrial Engineering and Other Applications of Applied Intelligent Systems, IEA/AIE 2017, Proceedings. Ali, M., Benferhat, S. & Tabia, K. (eds.). Springer Verlag, p. 374-385 12 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10351 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Evaluation of the informatician perspective: Determining types of research papers preferred by clinicians

Ru, B., Wang, X. & Yao, L., Jul 5 2017, In : BMC Medical Informatics and Decision Making. 17, 74.

Research output: Contribution to journalReview article

2 Scopus citations

Identifying serendipitous drug usages in patient forum data a feasibility study

Ru, B., Warner-Hillard, C., Ge, Y. & Yao, L., Jan 1 2017, HEALTHINF 2017 - 10th International Conference on Health Informatics, Proceedings; Part of 10th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2017. Gamboa, H., Fred, A., van den Broek, E. L. & Vaz, M. (eds.). SciTePress, Vol. 5. p. 106-118 13 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Integration of Accountable Care Organization and Additional Hospital Data into CMS Referral Analytics System

Ru, B., Wu, Q., Wang, X., Yao, L. & Jia, Y., Sep 8 2017, Proceedings - 2017 IEEE International Conference on Healthcare Informatics, ICHI 2017. Cummins, M., Facelli, J., Meixner, G., Giraud-Carrier, C. & Nakajima, H. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 357-361 5 p. 8031174

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Preface

Wang, F., Yao, L. & Luo, G., Jan 1 2017, In : Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 10186 LNCS

Research output: Contribution to journalEditorial

Visual FHIR: An Interactive Browser to Navigate HL7 FHIR Specification

Hong, N., Wang, K., Yao, L. & Jiang, G. D., Sep 8 2017, Proceedings - 2017 IEEE International Conference on Healthcare Informatics, ICHI 2017. Institute of Electrical and Electronics Engineers Inc., p. 26-30 5 p. 8031128

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations
2016

A Content Analysis of Patient-Reported Medication Outcomes on Social Media

Ru, B., Harris, K. & Yao, L., Jan 29 2016, Proceedings - 15th IEEE International Conference on Data Mining Workshop, ICDMW 2015. Wu, X., Tuzhilin, A., Xiong, H., Dy, J. G., Aggarwal, C., Zhou, Z-H. & Cui, P. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 472-479 8 p. 7395706

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Pattern Genes Suggest Functional Connectivity of Organs

Qin, Y., Pan, J., Cai, M., Yao, L. & Ji, Z., May 26 2016, In : Scientific Reports. 6, 26501.

Research output: Contribution to journalArticle

3 Scopus citations
2015

30 Day hospital readmission analysis

Maddipatla, R. M., Hadzikadic, M., Misra, D. P. & Yao, L., Dec 22 2015, Proceedings - 2015 IEEE International Conference on Big Data, IEEE Big Data 2015. Luo, F., Ogan, K., Zaki, M. J., Haas, L., Ooi, B. C., Kumar, V., Rachuri, S., Pyne, S., Ho, H., Hu, X., Yu, S., Hsiao, M. H-I. & Li, J. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 2922-2924 3 p. 7364123

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations

Health ROI as a measure of misalignment of biomedical needs and resources

Yao, L., Li, Y., Ghosh, S., Evans, J. A. & Rzhetsky, A., Aug 7 2015, In : Nature biotechnology. 33, 8, p. 807-811 5 p.

Research output: Contribution to journalLetter

13 Scopus citations
2012

In silico search for drug targets of natural compounds

Yao, L., Jul 1 2012, In : Current Pharmaceutical Biotechnology. 13, 9, p. 1632-1639 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
2011

Benchmarking ontologies: Bigger or better?

Yao, L., Divoli, A., Mayzus, I., Evans, J. A. & Rzhetsky, A., Jan 2011, In : PLoS computational biology. 7, 1, e1001055.

Research output: Contribution to journalArticle

19 Scopus citations

Electronic health records: Implications for drug discovery

Yao, L., Zhang, Y., Li, Y., Sanseau, P. & Agarwal, P., Jul 1 2011, In : Drug Discovery Today. 16, 13-14, p. 594-599 6 p.

Research output: Contribution to journalReview article

27 Scopus citations
2010

Novel opportunities for computational biology and sociology in drug discovery

Yao, L., Evans, J. A. & Rzhetsky, A., Apr 1 2010, In : Trends in Biotechnology. 28, 4, p. 161-170 10 p.

Research output: Contribution to journalComment/debate

15 Scopus citations
2009

Novel opportunities for computational biology and sociology in drug discovery

Yao, L., Evans, J. A. & Rzhetsky, A., Sep 1 2009, In : Trends in Biotechnology. 27, 9, p. 531-540 10 p.

Research output: Contribution to journalReview article

12 Scopus citations
2008

Quantitative systems-level determinants of human genes targeted by successful drugs

Yao, L. & Rzhetsky, A., Feb 1 2008, In : Genome Research. 18, 2, p. 206-213 8 p.

Research output: Contribution to journalArticle

56 Scopus citations
2007

Does drug-target have a likeness?

Xu, H., Fang, Y., Yao, L., Chen, Y. & Chen, X., May 30 2007, In : Methods of Information in Medicine. 46, 3, p. 360-366 7 p.

Research output: Contribution to journalArticle

15 Scopus citations
2006

Internet resources related to drug action and human response: A review

Yao, L. X., Wu, Z. C., Ji, Z. L., Chen, Y. Z. & Chen, X., Aug 31 2006, In : Applied Bioinformatics. 5, 3, p. 131-139 9 p.

Research output: Contribution to journalReview article

5 Scopus citations
2003

Internet resources for proteins associated with drug therapeutic effects, adverse reactions and ADME

Ji, Z. L., Sun, L. Z., Chen, X., Zheng, C. J., Yao, L. X., Han, L. Y., Cao, Z. W., Wang, J. F., Yeo, W. K., Cai, C. Z. & Chen, Y. Z., Jun 15 2003, In : Drug Discovery Today. 8, 12, p. 526-529 4 p.

Research output: Contribution to journalShort survey

15 Scopus citations