• 729 Citations
  • 11 Scopus h-Index
19972019

Research output per year

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Research Output

  • 729 Citations
  • 11 Scopus h-Index
  • 36 Article
  • 6 Letter
  • 1 Comment/debate
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Article
2019

Acute leukemias harboring KMT2A/MLLT10 fusion: a 10-year experience from a single genomics laboratory

Peterson, J. F., Sukov, W. R., Pitel, B. A., Smoley, S. A., Pearce, K. E., Meyer, R. G., Williamson, C. M., Smadbeck, J., Vasmatzis, G., Hoppman, N. L., Greipp, P. T., Baughn, L. & Ketterling, R. P., Jan 1 2019, In : Genes Chromosomes and Cancer.

Research output: Contribution to journalArticle

3 Scopus citations

A near-haploid clone harboring a BCR/ABL1 gene fusion in an adult patient with newly diagnosed B-lymphoblastic leukemia

Peterson, J. F., Ketterling, R. P., Huang, L., Finn, L. E., Shi, M., Hoppman, N. L., Greipp, P. T. & Baughn, L., Sep 1 2019, In : Genes Chromosomes and Cancer. 58, 9, p. 665-668 4 p.

Research output: Contribution to journalArticle

Characterization of a cryptic IGH/CCND1 rearrangement in a case of mantle cell lymphoma with negative CCND1 FISH studies

Peterson, J. F., Baughn, L. B., Ketterling, R. P., Pitel, B. A., Smoley, S. A., Vasmatzis, G., Smadbeck, J. B., Greipp, P. T., Mangaonkar, A. A., Thompson, C. A., Parikh, S. A., Chen, D. & Viswanatha, D. S., Jan 1 2019, In : Blood Advances. 3, 8, p. 1298-1302 5 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Characterization of a rarely reported STAT5B/RARA gene fusion in a young adult with newly diagnosed acute promyelocytic leukemia with resistance to ATRA therapy

Peterson, J. F., He, R. R., Nayer, H., Cuevo, R. S., Smadbeck, J., Vasmatzis, G., Greipp, P. T., Ketterling, R. P., Hoppman, N. L. & Baughn, L., Sep 1 2019, In : Cancer Genetics. 237, p. 51-54 4 p.

Research output: Contribution to journalArticle

Characterization of TCF3 rearrangements in pediatric B-lymphoblastic leukemia/lymphoma by mate-pair sequencing (MPseq) identifies complex genomic rearrangements and a novel TCF3/TEF gene fusion

Rowsey, R. A., Smoley, S. A., Williamson, C. M., Vasmatzis, G., Smadbeck, J. B., Ning, Y., Greipp, P. T., Hoppman, N. L., Baughn, L. B., Ketterling, R. P. & Peterson, J. F., Oct 1 2019, In : Blood cancer journal. 9, 10, 81.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Detection of a cryptic NUP214/ABL1 gene fusion by mate-pair sequencing (MPseq) in a newly diagnosed case of pediatric T-lymphoblastic leukemia

Peterson, J. F., Pitel, B. A., Smoley, S. A., Smadbeck, J., Johnson, S. H., Vasmatzis, G., Koon, S. J., Webley, M. R., McGrath, M., Bayerl, M. G., Baughn, L., Rowsey, R. A., Ketterling, R. P., Greipp, P. T. & Hoppman, N. L., Apr 1 2019, In : Cold Spring Harbor molecular case studies. 5, 2

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
Open Access
2 Scopus citations

Mate pair sequencing improves detection of genomic abnormalities in acute myeloid leukemia

Aypar, U., Smoley, S. A., Pitel, B. A., Pearce, K. E., Zenka, R. M., Vasmatzis, G., Johnson, S. H., Smadbeck, J., Peterson, J. F., Geiersbach, K. B., Van Dyke, D. L., Thorland, E. C., Jenkins, R. B., Ketterling, R. P., Greipp, P. T., Kearney, H. M., Hoppman, N. L. & Baughn, L., Jan 1 2019, In : European Journal of Haematology. 102, 1, p. 87-96 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Molecular signatures of multiple myeloma progression through single cell RNA-Seq

Jang, J. S., Li, Y., Mitra, A. K., Bi, L., Abyzov, A., van Wijnen, A. J., Baughn, L., Van Ness, B., Rajkumar, S. V., Kumar, S. K. & Jen, J., Jan 1 2019, In : Blood Cancer Journal. 9, 1, 2.

Research output: Contribution to journalArticle

9 Scopus citations

Rapid assessment of hyperdiploidy in plasma cell disorders using a novel multi-parametric flow cytometry method

Sidana, S., Jevremovic, D., Ketterling, R. P., Tandon, N., Dispenzieri, A., Gertz, M., Greipp, P. T., Baughn, L., Buadi, F. K., Lacy, M., Morice, W., Hanson, C., Timm, M., Dingli, D. M., Hayman, S. R., Gonsalves, W., Kapoor, P., Kyle, R. A., Leung, N., Go, R. S. & 3 others, Lust, J. A., Rajkumar, S. V. & Kumar, S. K., Jan 1 2019, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

4 Scopus citations

The future of myeloma precision medicine: integrating the compendium of known drug resistance mechanisms with emerging tumor profiling technologies

Harding, T., Baughn, L., Kumar, S. K. & Van Ness, B., Jan 1 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

8 Scopus citations

Use of mate-pair sequencing to characterize a complex cryptic BCR/ABL1 rearrangement observed in a newly diagnosed case of chronic myeloid leukemia

Peterson, J. F., Pitel, B. A., Smoley, S. A., Smadbeck, J., Johnson, S. H., Vasmatzis, G., Kearney, H. M., Greipp, P. T., Hoppman, N. L., Baughn, L. & Ketterling, R. P., Jan 1 2019, In : Human Pathology.

Research output: Contribution to journalArticle

3 Scopus citations

Whole Genome Mate-pair Sequencing of Plasma Cell Neoplasm as a Novel Diagnostic Strategy: A Case of Unrecognized t(2;11) Structural Variation

Peterson, J. F., Meyer, R. G., Smoley, S. A., Webley, M., Smadbeck, J., Vasmatzis, G., Pearce, K., Greipp, P. T., Ketterling, R. P., Craig, F. E., Stewart, A. K. & Baughn, L., Jan 1 2019, In : Clinical Lymphoma, Myeloma and Leukemia.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Constitutional chromosome rearrangements that mimic the 2017 world health organization “acute myeloid leukemia with recurrent genetic abnormalities”: A study of three cases and review of the literature

Peterson, J. F., Pitel, B. A., Smoley, S. A., Smadbeck, J., Johnson, S. H., Vasmatzis, G., Pearce, K. E., He, R., Kelemen, K., Al-Mondhiry, H. A. B., Lamparella, N. E., Hoppman, N. L., Kearney, H. M., Baughn, L., Ketterling, R. P. & Greipp, P. T., Jan 1 2018, (Accepted/In press) In : Cancer genetics.

Research output: Contribution to journalArticle

Core-binding factor acute myeloid leukemia with t(8;21): Risk factors and a novel scoring system (I-CBFit)

Ustun, C., Morgan, E., Moodie, E. E. M., Pullarkat, S., Yeung, C., Broesby-Olsen, S., Ohgami, R., Kim, Y., Sperr, W., Vestergaard, H., Chen, D., Kluin, P. M., Dolan, M., Mrózek, K., Czuchlewski, D., Horny, H. P., George, T. I., Kristensen, T. K., Ku, N. K., Yi, C. A. & 26 others, Møller, M. B., Marcucci, G., Baughn, L., Schiefer, A. I., Hilberink, J. R., Pullarkat, V., Shanley, R., Kohlschmidt, J., Coulombe, J., Salhotra, A., Soma, L., Cho, C., Linden, M. A., Akin, C., Gotlib, J., Hoermann, G., Hornick, J., Nakamura, R., Deeg, J., Bloomfield, C. D., Weisdorf, D., Litzow, M. R., Valent, P., Huls, G., Perales, M. A. & Borthakur, G., Sep 1 2018, In : Cancer Medicine. 7, 9, p. 4447-4455 9 p.

Research output: Contribution to journalArticle

6 Scopus citations
11 Scopus citations

KMT2A (MLL) rearrangements observed in pediatric/young adult T-lymphoblastic leukemia/lymphoma: A 10-year review from a single cytogenetic laboratory

Peterson, J. F., Baughn, L., Pearce, K. E., Williamson, C. M., Benevides Demasi, J. C., Olson, R. M., Goble, T. A., Meyer, R. G., Greipp, P. T. & Ketterling, R. P., Jan 1 2018, (Accepted/In press) In : Genes Chromosomes and Cancer.

Research output: Contribution to journalArticle

7 Scopus citations

Necrotizing enterocolitis in two siblings and an unrelated infant with overlapping chromosome 6q25 deletions

Esdal, H. C. D., Ghbeis, M. B., Saltzman, D. A., Hess, D., Hume, J. R., Reed, R. C., Berry, S. A., Hoggard, E., Hirsch, B., Baughn, L. & Schimmenti, L. A., May 1 2018, In : Molecular Syndromology. 9, 3, p. 141-148 8 p.

Research output: Contribution to journalArticle

SH2B3 aberrations enriched in iAMP21 B lymphoblastic leukemia

Baughn, L., Meredith, M. M., Oseth, L., Smolarek, T. A. & Hirsch, B., Oct 1 2018, In : Cancer genetics. 226-227, p. 30-35 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

The utilization of chromosomal microarray technologies for hematologic neoplasms: An ACLPS critical review

Peterson, J. F., Van Dyke, D. L., Hoppman, N. L., Kearney, H. M., Sukov, W. R., Greipp, P. T., Ketterling, R. P. & Baughn, L., Oct 1 2018, In : American Journal of Clinical Pathology. 150, 5, p. 375-384 10 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017

Buccal epithelial cells display somatic, bone marrow-derived CALR mutation

Gilles, S. R., Baughn, L. B., Schomaker, M. L., Courville, E. L., Nelson, A. C. & Sachs, Z., Nov 28 2017, In : Blood Advances. 1, 25, p. 2302-2306 5 p.

Research output: Contribution to journalArticle

Open Access

Functional convergence of histone methyltransferases EHMT1 and KMT2C involved in intellectual disability and autism spectrum disorder

Koemans, T. S., Kleefstra, T., Chubak, M. C., Stone, M. H., Reijnders, M. R. F., de Munnik, S., Willemsen, M. H., Fenckova, M., Stumpel, C. T. R. M., Bok, L. A., Sifuentes Saenz, M., Byerly, K. A., Baughn, L., Stegmann, A. P. A., Pfundt, R., Zhou, H., van Bokhoven, H., Schenck, A. & Kramer, J. M., Oct 1 2017, In : PLoS Genetics. 13, 10, e1006864.

Research output: Contribution to journalArticle

24 Scopus citations

Phenotypic and functional characterization of a bortezomib-resistant multiple myeloma cell line by flow and mass cytometry

Baughn, L., Sachs, Z., Noble-Orcutt, K. E., Mitra, A., Van Ness, B. G. & Linden, M. A., Aug 3 2017, In : Leukemia and Lymphoma. 58, 8, p. 1931-1940 10 p.

Research output: Contribution to journalArticle

6 Scopus citations
2016

CNV-RF Is a Random Forest–Based Copy Number Variation Detection Method Using Next-Generation Sequencing

Onsongo, G., Baughn, L., Bower, M., Henzler, C., Schomaker, M., Silverstein, K. A. T. & Thyagarajan, B., Nov 1 2016, In : Journal of Molecular Diagnostics. 18, 6, p. 872-881 10 p.

Research output: Contribution to journalArticle

9 Scopus citations
2015

Bosutinib, a Lyn/Btk inhibiting tyrosine kinase inhibitor, is ineffective in advanced systemic mastocytosis

Randall, N., Courville, E. L., Baughn, L., Afrin, L. & Ustun, C., Jan 1 2015, In : American Journal of Hematology. 90, 4, p. E74-E74

Research output: Contribution to journalArticle

8 Scopus citations

Integration of cytogenomic data for furthering the characterization of pediatric B-cell acute lymphoblastic leukemia: A multi-institution, multi-platform microarray study

Baughn, L., Biegel, J. A., South, S. T., Smolarek, T. A., Volkert, S., Carroll, A. J., Heerema, N. A., Rabin, K. R., Zweidler-McKay, P. A., Loh, M. & Hirsch, B., Jan 1 2015, In : Cancer genetics. 208, 1-2, p. 1-18 18 p.

Research output: Contribution to journalArticle

20 Scopus citations
2014

Utilization of translational bioinformatics to identify novel biomarkers of bortezomib resistance in multiple myeloma

Fall, D. J., Stessman, H., Patel, S. S., Sachs, Z., Van Ness, B. G., Baughn, L. & Linden, M. A., Jan 1 2014, In : Journal of Cancer. 5, 9, p. 720-727 8 p.

Research output: Contribution to journalArticle

16 Scopus citations
2013

Bortezomib resistance can be reversed by induced expression of plasma cell maturation markers in a mouse in vitro model of multiple myeloma.

Stessman, H. A. F., Mansoor, A., Zhan, F., Linden, M. A., Van Ness, B. & Baughn, L., Jan 1 2013, In : PLoS One. 8, 10

Research output: Contribution to journalArticle

12 Scopus citations

Profiling bortezomib resistance identifies secondary therapies in a mouse myeloma model

Stessman, H. A. F., Baughn, L., Sarver, A., Xia, T., Deshpande, R., Mansoor, A., Walsh, S. A., Sunderland, J. J., Dolloff, N. G., Linden, M. A., Zhan, F., Janz, S., Myers, C. L. & Van Ness, B. G., Jun 1 2013, In : Molecular Cancer Therapeutics. 12, 6, p. 1140-1150 11 p.

Research output: Contribution to journalArticle

42 Scopus citations
2011

Recombinase-mediated cassette exchange as a novel method to study somatic hypermutation in ramos cells

Baughn, L., Kalis, S. L., MacCarthy, T., Wei, L., Fan, M., Bergman, A. & Scharff, M. D., Sep 1 2011, In : mBio. 2, 5

Research output: Contribution to journalArticle

6 Scopus citations
2009

CDK2 phosphorylation of Smad2 disrupts TGF-β transcriptional regulation in resistant primary bone marrow myeloma cells

Baughn, L., Di Liberto, M., Niesvizky, R., Cho, H. J., Jayabalan, D., Lane, J., Liu, F. & Chen-Kiang, S., Feb 15 2009, In : Journal of Immunology. 182, 4, p. 1810-1817 8 p.

Research output: Contribution to journalArticle

27 Scopus citations
2006

A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6

Baughn, L., Di Liberto, M., Wu, K., Toogood, P. L., Louie, T., Gottschalk, R., Niesvizky, R., Cho, H., Ely, S., Moore, M. A. S. & Chen-Kiang, S., Aug 1 2006, In : Cancer Research. 66, 15, p. 7661-7667 7 p.

Research output: Contribution to journalArticle

165 Scopus citations
2005

Disruption of the Shc/Grb2 complex during Abelson virus transformation affects proliferation, but not apoptosis

Baughn, L. & Rosenberg, N., Feb 1 2005, In : Journal of Virology. 79, 4, p. 2325-2334 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Mutually exclusive cyclin-dependent kinase 4/cyclin D1 and cyclin-dependent kinase 6/cyclin D2 pairing inactivates retinoblastoma protein and promotes cell cycle dysregulation in multiple myeloma

Ely, S., Di Liberto, M., Niesvizky, R., Baughn, L., Cho, H. J., Hatada, E. N., Knowles, D. M., Lane, J. & Chen-Kiang, S., Dec 15 2005, In : Cancer Research. 65, 24, p. 11345-11353 9 p.

Research output: Contribution to journalArticle

87 Scopus citations
1998

Overexpression, purification, and characterization of the cloned metallo-β-lactamase L1 from Stenotrophomonas maltophilia

Crowder, M. W., Walsh, T. R., Baughn, L., Pettit, M. & Spencer, J., Apr 1 1998, In : Antimicrobial Agents and Chemotherapy. 42, 4, p. 921-926 6 p.

Research output: Contribution to journalArticle

140 Scopus citations
1997

Glyoxalase II from A. thialana requires Zn(II) for catalytic activity

Crowder, M. W., Maiti, M. K., Baughn, L. & Makaroff, C. A., Dec 1 1997, In : FEBS Letters. 418, 3, p. 351-354 4 p.

Research output: Contribution to journalArticle

48 Scopus citations