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1979 …2019
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Research Output 1990 2019

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2006
7 Citations (Scopus)

Review - 3D micro CT imaging of renal micro-structural changes

Gössl, M., Bentley, M. D. & Lerman, L. O., Mar 2006, In : Nephron - Clinical Practice. 103, 2

Research output: Contribution to journalArticle

Kidney
Nephrons
Chronic Renal Insufficiency
X-Ray Microtomography
Renal Hypertension
37 Citations (Scopus)

Role of oxidative stress in remodeling of the myocardial microcirculation in hypertension

Zhu, X. Y., Daghini, E., Chade, A. R., Rodriguez-Porcel, M. G., Napoli, C., Lerman, A. & Lerman, L. O., Aug 2006, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 26, 8, p. 1746-1752 7 p.

Research output: Contribution to journalArticle

Microcirculation
Oxidative Stress
Hypertension
Antioxidants
Microvessels
105 Citations (Scopus)

Simvastatin promotes angiogenesis and prevents microvascular remodeling in chronic renal ischemia

Chade, A. R., Zhu, X., Mushin, O. P., Napoli, C., Lerman, A. & Lerman, L. O., Aug 2006, In : FASEB Journal. 20, 10

Research output: Contribution to journalArticle

Renal Artery Obstruction
Simvastatin
ischemia
angiogenesis
Ischemia
21 Citations (Scopus)

The Porcine Remnant Kidney Model of Chronic Renal Insufficiency

Misra, S., Gordon, J. D., Fu, A. A., Glockner, J., Chade, A. R., Mandrekar, J., Lerman, L. O. & Mukhopadhyay, D., Oct 2006, In : Journal of Surgical Research. 135, 2, p. 370-379 10 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Swine
Kidney
Nephrectomy
Arterial Pressure
52 Citations (Scopus)

Vascular wall elasticity measurement by magnetic resonance imaging

Woodrum, D. A., Romano, A. J., Lerman, A., Pandya, U. H., Brosh, D., Rossman, P. J., Lerman, L. O. & Ehman, R. L., Sep 2006, In : Magnetic Resonance in Medicine. 56, 3, p. 593-600 8 p.

Research output: Contribution to journalArticle

Elasticity
Elasticity Imaging Techniques
Blood Vessels
Magnetic Resonance Imaging
Pathologic Constriction
2005
118 Citations (Scopus)

Animal models of hypertension: An overview

Lerman, L. O., Chade, A. R., Sica, V. & Napoli, C., Sep 2005, In : Journal of Laboratory and Clinical Medicine. 146, 3, p. 160-173 14 p.

Research output: Contribution to journalArticle

Animals
Animal Models
Hypertension
Theoretical Models
Blood pressure
65 Citations (Scopus)

Beneficial effects of concurrent autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the mouse hindlimb

Napoli, C., Williams-Ignarro, S., De Nigris, F., De Rosa, G., Lerman, L. O., Farzati, B., Matarazzo, A., Sica, G., Botti, C., Fiore, A., Byrns, R. E., Sumi, D., Sica, V. & Ignarro, L. J., Nov 22 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 47, p. 17202-17206 5 p.

Research output: Contribution to journalArticle

Hindlimb
Cell- and Tissue-Based Therapy
Bone Marrow Cells
Ischemia
Blood Vessels
113 Citations (Scopus)

Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthase activity at sites of perturbed shear stress

De Nigris, F., Williams-Ignarro, S., Lerman, L. O., Crimi, E., Botti, C., Mansueto, G., D'Armiento, F. P., De Rosa, G., Sica, V., Ignarro, L. J. & Napoli, C., Mar 29 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 13, p. 4896-4901 6 p.

Research output: Contribution to journalArticle

Punicaceae
Nitric Oxide Synthase Type III
Atherosclerosis
Genes
Nitric Oxide Synthase
46 Citations (Scopus)

Concurrent treatment with renin-angiotensin system blockers and acetylsalicylic acid reduces nuclear factor κB activation and C-reactive protein expression in human carotid artery plaques

Sattler, K. J. E., Woodrum, J. E., Galili, O., Olson, M., Samee, S., Meyer, F. B., Zhu, X. Y., Lerman, L. O. & Lerman, A., Jan 2005, In : Stroke. 36, 1, p. 14-20 7 p.

Research output: Contribution to journalArticle

Carotid Stenosis
Renin-Angiotensin System
C-Reactive Protein
Aspirin
Cyclooxygenase 2
50 Citations (Scopus)
Adventitia
Hypercholesterolemia
Hypertension
Vasa Vasorum
Diet
38 Citations (Scopus)

Effects of proteasome inhibition on the kidney in experimental hypercholesterolemia

Chade, A. R., Herrmann, J., Zhu, X., Krier, J. D., Lerman, A. & Lerman, L. O., 2005, In : Journal of the American Society of Nephrology. 16, 4, p. 1005-1012 8 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Hypercholesterolemia
Proteasome Inhibitors
Kidney
Endothelins
30 Citations (Scopus)
Vasa Vasorum
Adventitia
Mammary Arteries
Hypercholesterolemia
Coronary Vessels
100 Citations (Scopus)

Kidney in early atherosclerosis

Chade, A. R., Lerman, A. & Lerman, L. O., Jun 2005, In : Hypertension. 45, 6, p. 1042-1049 8 p.

Research output: Contribution to journalArticle

Atherosclerosis
Kidney
Chronic Renal Insufficiency
Dyslipidemias
Premature Mortality
49 Citations (Scopus)

KLF11-mediated repression antagonizes Sp1/sterol-responsive element-binding protein-induced transcriptional activation of caveolin-1 in response to cholesterol signaling

Cao, S., Fernandez-Zapico, M. E., Jin, D., Puri, V., Cook, T. A., Lerman, L. O., Zhu, X. Y., Urrutia, R. & Shah, V., Jan 21 2005, In : Journal of Biological Chemistry. 280, 3, p. 1901-1910 10 p.

Research output: Contribution to journalArticle

Caveolin 1
Sterols
Transcriptional Activation
Carrier Proteins
Chemical activation
15 Citations (Scopus)

Non-invasive evaluation of bilateral renal regional blood flow and tubular dynamics during acute unilateral ureteral obstruction

Pelaez, L. I., Juncos, L. A., Stulak, J. M., Lerman, L. O. & Romero, J. C., Jan 2005, In : Nephrology Dialysis Transplantation. 20, 1, p. 83-88 6 p.

Research output: Contribution to journalArticle

Ureteral Obstruction
Renal Circulation
Regional Blood Flow
Hemodynamics
X Ray Computed Tomography
112 Citations (Scopus)

Oxidative stress in obstructive sleep apnoea

Svatikova, A., Wolk, R., Lerman, L. O., Juncos, L. A., Greene, E. L., McConnell, J. P. & Somers, V., Nov 2005, In : European Heart Journal. 26, 22, p. 2435-2439 5 p.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Oxidative Stress
Lipid Peroxidation
Isoprostanes
Continuous Positive Airway Pressure
55 Citations (Scopus)

Pathways of renal fibrosis and modulation of matrix turnover in experimental hypercholesterolemia

Chade, A. R., Mushin, O. P., Zhu, X., Rodriguez-Porcel, M. G., Grande, J. P., Textor, S. C., Lerman, A. & Lerman, L. O., Oct 2005, In : Hypertension. 46, 4, p. 772-779 8 p.

Research output: Contribution to journalArticle

Hypercholesterolemia
Fibrosis
Kidney
Diet
Matrix Metalloproteinases
9 Citations (Scopus)

The ubiquitin-proteasome system - Micro target for macro intervention?

Herrmann, J., Ciechanover, A., Lerman, L. O. & Lerman, A., 2005, In : International Journal of Cardiovascular Interventions. 7, 1, p. 5-13 9 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Ubiquitin
Biological Phenomena
Proteasome Inhibitors
Drug-Eluting Stents
2004
55 Citations (Scopus)

Adventitial vasa vasorum heterogeneity among different vascular beds

Galili, O., Herrmann, J., Woodrum, J., Sattler, K. J., Lerman, L. O. & Lerman, A., Sep 2004, In : Journal of Vascular Surgery. 40, 3, p. 529-535 7 p.

Research output: Contribution to journalArticle

Vasa Vasorum
Adventitia
Blood Vessels
Vascular Diseases
Femoral Artery
100 Citations (Scopus)

Antioxidant Intervention Attenuates Myocardial Neovascularization in Hypercholesterolemia

Zhu, X. Y., Rodriguez-Porcel, M. G., Bentley, M. D., Chade, A. R., Sica, V., Napoli, C., Caplice, N., Ritman, E. L., Lerman, A. & Lerman, L. O., May 4 2004, In : Circulation. 109, 17, p. 2109-2115 7 p.

Research output: Contribution to journalArticle

Hypercholesterolemia
Antioxidants
Hypoxia-Inducible Factor 1
Vascular Endothelial Growth Factor A
Microvessels
98 Citations (Scopus)

Antioxidant Intervention Blunts Renal Injury in Experimental Renovascular Disease

Chade, A. R., Rodriguez-Porcel, M. G., Herrmann, J., Zhu, X., Grande, J. P., Napoli, C., Lerman, A. & Lerman, L. O., Apr 2004, In : Journal of the American Society of Nephrology. 15, 4, p. 958-966 9 p.

Research output: Contribution to journalArticle

Nonpenetrating Wounds
Antioxidants
Kidney
Vitamins
Renal Circulation
60 Citations (Scopus)

Antioxidant intervention prevents renal neovascularization in hypercholesterolemic pigs

Chade, A. R., Bentley, M. D., Zhu, X., Rodriguez-Porcel, M. G., Niemeyer, S., Amores-Arriaga, B., Napoli, C., Ritman, E. L., Lerman, A. & Lerman, L. O., Jul 2004, In : Journal of the American Society of Nephrology. 15, 7, p. 1816-1825 10 p.

Research output: Contribution to journalArticle

Hypercholesterolemia
Swine
Antioxidants
Kidney
Vitamins
114 Citations (Scopus)

Blood oxygen level-dependent measurement of acute intra-renal ischemia

Juillard, L., Lerman, L. O., Kruger, D. G., Haas, J. A., Rucker, B. C., Polzin, J. A., Riederer, S. J. & Romero, J. C., Mar 2004, In : Kidney International. 65, 3, p. 944-950 7 p.

Research output: Contribution to journalArticle

Ischemia
Oxygen
Kidney
Renal Artery Obstruction
Renal Circulation
67 Citations (Scopus)

Comparison of acute and chronic antioxidant interventions in experimental renovascular disease

Chade, A. R., Krier, J. D., Rodriguez-Porcel, M. G., Breen, J. F., McKusick, M. A., Lerman, A. & Lerman, L. O., Jun 2004, In : American Journal of Physiology - Renal Physiology. 286, 6 55-6

Research output: Contribution to journalArticle

Antioxidants
Kidney
Vitamins
Oxidative Stress
Renal Circulation
117 Citations (Scopus)

Cortical microvascular remodeling in the stenotic kidney: Role of increased oxidative stress

Zhu, X. Y., Chade, A. R., Rodriguez-Porcel, M. G., Bentley, M. D., Ritman, E. L., Lerman, A. & Lerman, L. O., Oct 2004, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 24, 10, p. 1854-1859 6 p.

Research output: Contribution to journalArticle

Renal Artery Obstruction
Oxidative Stress
Kidney
Hypoxia-Inducible Factor 1
Antioxidants
1 Citation (Scopus)

Erratum: Long-term combined beneficial effects of physical training and metabolic treatment on atherosclerosis in hypercholesterolemic mice (Proceedings of the National Academy of Sciences of the United States of America (June 8, 2004) 101, 23 (8797-8802))

Napoli, C., Williams-Ignarro, S., De Nigris, F., Lerman, L. O., Rossi, L., Guarino, C., Mansueto, G., Di Tuoro, F., Pignalosa, O., De Rosa, G., Sica, V. & Ignarro, L. J., Dec 28 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 52, p. 18262 1 p.

Research output: Contribution to journalArticle

Atherosclerosis
1 Citation (Scopus)
Proteasome Endopeptidase Complex
Ubiquitin
Cardiovascular Diseases
Research
36 Citations (Scopus)

Long-Term Antioxidant Intervention Improves Myocardial Microvascular Function in Experimental Hypertension

Rodriguez-Porcel, M. G., Herrmann, J., Chade, A. R., Krier, J. D., Breen, J. F., Lerman, A. & Lerman, L. O., Feb 2004, In : Hypertension. 43, 2 II, p. 493-498 6 p.

Research output: Contribution to journalArticle

Antioxidants
Hypertension
Capillary Permeability
Perfusion
Dobutamine
87 Citations (Scopus)

Long-term combined beneficial effects of physical training and metabolic treatment on atherosclerosis in hypercholesterolemic mice

Napoli, C., Williams-Ignarro, S., De Nigris, F., Lerman, L. O., Rossi, L., Guarino, C., Mansueto, G., Di Tuoro, F., Pignalosa, O., De Rosa, G., Sica, V. & Ignarro, L. J., Jun 8 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 23, p. 8797-8802 6 p.

Research output: Contribution to journalArticle

Atherosclerosis
Exercise
Arginine
Antioxidants
Drinking Water
8 Citations (Scopus)

Relation of nonperfused myocardial volume and surface area to left ventricular performance in coronary microembolization

Malyar, N. M., Lerman, L. O., Gössl, M., Beighley, P. E. & Ritman, E. L., Oct 5 2004, In : Circulation. 110, 14, p. 1946-1952 7 p.

Research output: Contribution to journalArticle

Myocardium
Left Ventricular Dysfunction
Stroke Volume
Swine
X Ray Computed Tomography
145 Citations (Scopus)

The ubiquitin-proteasome system in cardiovascular diseases - A hypothesis extended

Herrmann, J., Ciechanover, A., Lerman, L. O. & Lerman, A., Jan 1 2004, In : Cardiovascular Research. 61, 1, p. 11-21 11 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Ubiquitin
Cardiovascular Diseases
Atherosclerosis
Proteasome Inhibitors
2003
20 Citations (Scopus)

Angiotensin II AT1 receptor blockade improves renal perfusion in hypercholesterolemia

Chade, A. R., Rodriguez-Porcel, M. G., Rippentrop, S. J., Lerman, A. & Lerman, L. O., Feb 1 2003, In : American Journal of Hypertension. 16, 2, p. 111-115 5 p.

Research output: Contribution to journalArticle

Angiotensin Type 1 Receptor
Hypercholesterolemia
Angiotensin II
Perfusion
Kidney
94 Citations (Scopus)

Beneficial effects of antioxidants and L-arginine on oxidation-sensitive gene expression and endothelial NO synthase activity at sites of disturbed shear stress

De Nigris, F., Lerman, L. O., Ignarro, S. W., Sica, G., Lerman, A., Palinski, W., Ignarro, L. J. & Napoli, C., Feb 4 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 3, p. 1420-1425 6 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase
Arginine
Atherosclerosis
Antioxidants
Gene Expression
61 Citations (Scopus)

Beneficial effects of antioxidant vitamins on the stenotic kidney

Chade, A. R., Rodriguez-Porcel, M. G., Herrmann, J., Krier, J. D., Zhu, X., Lerman, A. & Lerman, L. O., Oct 1 2003, In : Hypertension. 42, 4 I, p. 605-612 8 p.

Research output: Contribution to journalArticle

Renal Artery Obstruction
Vitamins
Antioxidants
Kidney
Oxidative Stress
34 Citations (Scopus)

c-Myc oncoprotein: cell cycle-related events and new therapeutic challenges in cancer and cardiovascular diseases.

de Nigris, F., Sica, V., Herrmann, J., Condorelli, G., Chade, A. R., Tajana, G., Lerman, A., Lerman, L. O. & Napoli, C., Jul 2003, In : Cell cycle (Georgetown, Tex.). 2, 4, p. 325-328 4 p.

Research output: Contribution to journalArticle

Oncogene Proteins
Atherosclerosis
Cell Cycle
Cardiovascular Diseases
Genes
1458 Citations (Scopus)

Endothelial dysfunction: A marker of atherosclerotic risk

Bonetti, P. O., Lerman, L. O. & Lerman, A., Feb 1 2003, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 23, 2, p. 168-175 8 p.

Research output: Contribution to journalArticle

Atherosclerosis
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Vascular Endothelium
Genetic Predisposition to Disease
Angiotensin-Converting Enzyme Inhibitors
42 Citations (Scopus)

Endothelin-1 receptor blockade prevents renal injury in experimental hypercholesterolemia

Chade, A. R., Best, P., Rodriguez-Porcel, M. G., Herrmann, J., Zhu, X., Sawamura, T., Napoli, C., Lerman, A. & Lerman, L. O., Sep 1 2003, In : Kidney International. 64, 3, p. 962-969 8 p.

Research output: Contribution to journalArticle

Endothelin A Receptors
Hypercholesterolemia
Endothelins
Kidney
Wounds and Injuries
9 Citations (Scopus)
Endothelin A Receptors
Hypercholesterolemia
Adenosine
Perfusion
Diet
Hypercholesterolemia
Blood Vessels
Antioxidants
Kidney
5 Citations (Scopus)

Glycoxidation of Low-Density Lipoprotein Increases TUNEL Positivity and CPP32 Activation in Human Coronary Cells

De Nigris, F., Tajana, G., Condorelli, M., D'Armiento, F. P., Sica, G., Lerman, L. O. & Napoli, C., 2003, In : Annals of the New York Academy of Sciences. 1010, p. 710-715 6 p.

Research output: Contribution to journalArticle

In Situ Nick-End Labeling
LDL Lipoproteins
Glycosylation
Chemical activation
Oxidation
69 Citations (Scopus)
Hypercholesterolemia
Hypertension
Oxidative Stress
Coronary Vessels
Diet
34 Citations (Scopus)

Hypertension exacerbates the effect of hypercholesterolemia on the myocardial microvasculature

Rodriguez-Porcel, M. G., Lerman, A., Herrmann, J., Schwartz, R. S., Sawamura, T., Condorelli, M., Napoli, C. & Lerman, L. O., May 1 2003, In : Cardiovascular Research. 58, 1, p. 213-221 9 p.

Research output: Contribution to journalArticle

Microvessels
Hypercholesterolemia
Hypertension
Blood Vessels
Oxidative Stress
53 Citations (Scopus)

Lipid-lowering-independent effects of simvastatin on the kidney in experimental hypercholesterolaemia

Wilson, S. H., Chade, A. R., Feldstein, A., Sawamura, T., Napoli, C., Lerman, A. & Lerman, L. O., Apr 1 2003, In : Nephrology Dialysis Transplantation. 18, 4, p. 703-709 7 p.

Research output: Contribution to journalArticle

Simvastatin
Hypercholesterolemia
Kidney
Lipids
Diet
126 Citations (Scopus)

Mechanisms of renal structural alterations in combined hypercholesterolemia and renal artery stenosis

Chade, A. R., Rodriguez-Porcel, M. G., Grande, J. P., Zhu, X., Sica, V., Napoli, C., Sawamura, T., Textor, S. C., Lerman, A. & Lerman, L. O., Jul 1 2003, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 23, 7, p. 1295-1301 7 p.

Research output: Contribution to journalArticle

Renal Artery Obstruction
Hypercholesterolemia
Kidney
Swine
Fibrosis
56 Citations (Scopus)

Microarray analysis: A novel research tool for cardiovascular scientists and physicians

Napoli, C., Lerman, L. O., Sica, V., Lerman, A., Tajana, G. & De Nigris, F., Jun 1 2003, In : Heart. 89, 6, p. 597-604 8 p.

Research output: Contribution to journalArticle

Microarray Analysis
Physicians
Gene Expression
Oligonucleotides
Cardiovascular Diseases
99 Citations (Scopus)

Oxidation-sensitive mechanisms, vascular apoptosis and atherosclerosis

De Nigris, F., Lerman, A., Ignarro, L. J., Williams-Ignarro, S., Sica, V., Baker, A. H., Lerman, L. O., Geng, Y. J. & Napoli, C., Aug 1 2003, In : Trends in Molecular Medicine. 9, 8, p. 351-359 9 p.

Research output: Contribution to journalArticle

Blood Vessels
Atherosclerosis
Apoptosis
Lipoproteins
Oxidative Stress
49 Citations (Scopus)
Oxidative stress
Ubiquitination
Proteasome Endopeptidase Complex
Ubiquitin
Atherosclerosis
4 Citations (Scopus)

Renal blood flow in hypercholesterolemic pigs is increased by chronic antioxidant treatment

De Nigris, F., Demontis, M. P., Rodriguez-Porcel, M. G., Anania, V., Lerman, L. O. & Napoli, C., Apr 2003, In : Journal of Veterinary Pharmacology and Therapeutics. 26, 2, p. 113-116 4 p.

Research output: Contribution to journalArticle

Renal Circulation
blood flow
Swine
Antioxidants
kidneys
412 Citations (Scopus)

Statin effects beyond lipid lowering - Are they clinically relevant?

Bonetti, P. O., Lerman, L. O., Napoli, C. & Lerman, A., Feb 2003, In : European Heart Journal. 24, 3, p. 225-248 24 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factors
Endothelial Growth Factors
Pathologic Neovascularization
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Biological Models